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Bacteriophage that infects Escherichia coli
Lambda phage, also known as λ phage, (coliphage λ, scientific name Lambdavirus lambda) is a bacterial virus, or bacteriophage, that infects the bacterial
Lambda_phage
Species of virus
undergoing a lysogenic cycle the phage genome exists as a plasmid in the bacterium unlike other phages (e.g. the lambda phage) that integrate into the host
P1_phage
InterPro Family
important transcription factor in the life cycle of lambda phage. It is encoded in the lambda phage genome by the 291 base pair cII gene. cII plays a key
CII_protein
Process of virus reproduction
a bacterium. Temperate phages (such as lambda phage) can reproduce using both the lytic and the lysogenic cycle. How a phage decides which cycle to enter
Lysogenic_cycle
Type of hybrid plasmid
A cosmid is a type of hybrid plasmid that contains a Lambda phage cos sequence. Often used as cloning vectors in genetic engineering, cosmids can be used
Cosmid
Virus that infects bacteria
186 phage λ phage Φ6 phage Φ29 phage ΦX174 Bacteriophage φCb5 G4 phage M13 phage MS2 phage (23–28 nm in size) N4 phage P1 phage P2 phage P4 phage R17
Bacteriophage
Genus of viruses
Originally a group of all so-called lambdoid phages (synonyms Lambda-like viruses, Lambda-like phages, Lambda phage group), its scope has narrowed significantly
Lambdavirus
well as phage packaging in cells. The article discusses the transfer of genetic information from E. coli to Salmonella cells (via lambda phage) and how
Integration_host_factor
American microbiologist (1922–2006)
a pioneer of bacterial genetics. She discovered the bacterial virus lambda phage and the bacterial fertility factor F, devised the first implementation
Esther_Lederberg
DNA experiment
1972 when he combined DNA from the monkey virus SV40 with that of the lambda phage. Experiments on hereditary material during the time of the Hershey–Chase
Hershey–Chase_experiment
American biochemist
Department of Biology at Stanford University. His pioneering work on Lambda phage helped to advance molecular biology in the late 20th century. An important
Allan_M._Campbell
Collection of the total genomic DNA from a single organism
After a genomic library is constructed with a viral vector, such as lambda phage, the titer of the library can be determined. Calculating the titer allows
Genomic_library
Molecular biology method for cloning DNA fragments
sites from the lambda/phage chromosome (attP) and the bacteria (attB). As a result of recombination between the attP and attB sites, the phage integrates
Gateway_Technology
Therapeutic use of bacteriophages to treat bacterial infections
Phage therapy, viral phage therapy, or phagotherapy is the therapeutic use of bacteriophages for the treatment of pathogenic bacterial infections. This
Phage_therapy
found in the Transporter Classification Database. Lambda holin S (Lysis protein S of phage lambda, holin S105; TC# 1.E.2.1.1) is the prototype for class
Lambda_holin_family
Molecule that carries genetic information
(December 1976). "Construction of hybrid viruses containing SV40 and lambda phage DNA segments and their propagation in cultured monkey cells". Cell. 9
DNA
Site-specific recombinase technology
starvation. Phages like the lambda phage use their site specific recombinases to integrate their DNA into the host genome during lysogeny. P1 phage DNA on
Cre-Lox_recombination
Manipulation of an organism's genome
into DNA of Simian Virus 40: circular SV40 DNA molecules containing lambda phage genes and the galactose operon of Escherichia coli". Proceedings of the
Genetic_engineering
DNA-based cloning vector
Filamentous phages retard bacterial growth but, contrasting with the lambda phage and the T7 phage, are not generally lytic. Helper phages are usually
Phagemid
Chemical compound
infection of E. coli by bacteriophage lambda, with subunit ManY and ManZ being sufficient for proper lambda phage infection. MANXYZ possesses four domains
Mannose
Topics referred to by the same term
series Lambda Lambda Lambda, an American fraternity inspired by the fictional fraternity Lambda Legal, an American civil rights organization Lambda phage, a
Lambda_(disambiguation)
Family of glycoside hydrolases
17). This family includes lambda phage lysozyme and Escherichia coli T4 phage endolysin. Lysozyme helps to release mature phage particles from the cell
Glycoside_hydrolase_family_24
Process of determining the nucleic acid sequence
current sequencing schemes, were used to sequence the cohesive ends of lambda phage DNA. Between 1970 and 1973, Wu, scientist Radha Padmanabhan and colleagues
DNA_sequencing
Bias against acknowledging the achievements of women scientists
Furthermore, she did not receive recognition for her discovery of the lambda phage or for her studies on the F fertility factor that created a foundation
Matilda_effect
American microbiologist
lambda phage was successful for the arabinose operon in her testing. Gottesman's later research at the National Institutes of Health used this lambda
Susan_Gottesman
Class of enzymes
peptidoglycan matrix. The prototypical holin is the lambda phage S protein, which assists the lambda phage R protein (lysin). All holins embed themselves in
Lysin
DNA pattern affecting anatomy development
structural similarity to prokaryotic transcription factors, such as lambda phage proteins that alter the expression of genes in prokaryotes. The HTH motif
Homeobox
Kinetochore Klinefelter syndrome Knockout Lac operon Lagging strand Lambda phage Lateral inhibition Leader peptide gene Leader sequence (mRNA) Leading
Index_of_genetics_articles
Biotechnology for gene delivery
Paul Berg developed the first viral vector, incorporating DNA from the lambda phage into the polyomavirus SV40 to infect kidney cells maintained in culture
Viral_vector
American molecular biologist, biochemist and geneticist
American molecular biologist, biochemist, and geneticist, whose work on the lambda phage advanced the understanding of viral infections and gene regulation inside
Harrison_Echols
Simple model of a polymer
persistence length increases. Experimental data from the stretching of Lambda phage DNA is shown to the right, with force measurements determined by analysis
Worm-like_chain
Genetic transcription mechanism in prokaryotes
Antitermination is used by some phages to regulate progression from one stage of gene expression to the next. The lambda gene N, codes for an antitermination
Antitermination
Species of virus
into DNA of Simian Virus 40: circular SV40 DNA molecules containing lambda phage genes and the galactose operon of Escherichia coli". Proceedings of the
Genetically_modified_virus
Method of bacterial gene transfer
(conjugative replication similar to the rolling circle replication of lambda phage). Conjugative replication may require a second nick before successful
Bacterial_conjugation
Protein and protein family produced by a bacterial virus
encoded by NgoPhi2), when expressed in E. coli, could substitute for the phage lambda S gene. Holin Lysin Transporter Classification Database Piekarowicz,
Pseudomonas_phage_F116_holin
Organism altered by genetic engineering
into DNA of Simian Virus 40: circular SV40 DNA molecules containing lambda phage genes and the galactose operon of Escherichia coli". Proceedings of the
Genetically_modified_organism
Caenorhabditis elegans – mouse – Saccharomyces cerevisiae – Escherichia coli – Lambda phage – Xenopus – chicken – zebrafish – Ciona intestinalis – amphioxus Techniques:
Outline_of_biology
Topics referred to by the same term
organization or Clinical Research Organization, for pharmaceuticals cro, a Lambda phage repressor protein Civil restraint order, against vexatious litigation
CRO
Cycle of viral reproduction
is the late genes. The following refers to the well-studied temperate phage lambda of E. coli.[citation needed] Immediate early genes: These genes are expressed
Lytic_cycle
American geneticist
Institute of Technology (MIT), where he studied the molecular biology of the lambda phage. Herskowitz worked with Ethan Signer, whose other students include Nancy
Ira_Herskowitz
into DNA of Simian Virus 40: Circular SV40 DNA Molecules Containing Lambda Phage Genes and the Galactose Operon of Escherichia coli". PNAS. 69 (10): 2904–09
History of genetic engineering
History_of_genetic_engineering
DNA molecules formed by human agency at a molecular level generating novel DNA sequences
into DNA of Simian Virus 40: Circular SV40 DNA molecules containing lambda phage genes and the galactose operon of Escherichia coli". Proceedings of the
Recombinant_DNA
kwashiorkor Lac repressor – lactic acid autotroph – lagging strand – lambda phage – larva – leading strand – leaf – White blood cells – lichen – life form
Index_of_biology_articles
exhibiting 3 putative transmembrane segments (TMSs). When cloned into lambda phage devoid of the S holin, it caused very late cell lysis, beginning 80 min
Hol118_family
Genetics as a theme in fiction
into DNA of Simian Virus 40: Circular SV40 DNA Molecules Containing Lambda Phage Genes and the Galactose Operon of Escherichia coli". PNAS. 69 (10): 2904–2909
Genetics_in_fiction
Bacteria
into pathogenic bacteria that is capable of producing harmful toxins. Lambda phage lysogenic cycle Lwoff, André (December 1953). "Lysogeny". Bacteriological
Lysogen
American biochemist, physicist and Nobel laureate (born 1932)
PMC 220206. PMID 16591435. Ptashne, Mark (February 1967). "Isolation of the lambda phage repressor". PNAS. 57 (2): 306–313. Bibcode:1967PNAS...57..306P. doi:10
Walter_Gilbert
Microbiologist
in bacteria, the lysis/lysogeny switch in lambda phage, the organization of the bacterial nucleoid, and phage therapy. Adhya was born in Kolkata, India
Sankar_Adhya
Biological method of DNA extraction and purification
L (2011). "A one-step miniprep for the isolation of plasmid DNA and lambda phage particles". PLOS ONE. 6 (8) e23457. Bibcode:2011PLoSO...623457L. doi:10
Plasmid_preparation
pioneer of bacterial genetics; contributions include the discovery of lambda phage, the transfer of genes between bacteria by specialized transduction,
List of Stanford University alumni
List_of_Stanford_University_alumni
Molecular mechanism
acids has also been shown. A classical example is the binding of the lambda phage repressor to its operators, which occurs cooperatively. Other examples
Cooperative_binding
missing link in phage lysis of gram-positive bacteria: gene 14 of Bacillus subtilis phage phi 29 encodes the functional homolog of lambda S protein". Journal
Phi29_holin_family
DNA replication in prokaryotes
(conjugative replication similar to the rolling circle replication of lambda phage). Conjugative replication may require a second nick before successful
Prokaryotic_DNA_replication
Small DNA molecule within a cell
clone DNA fragments of up to 15 kbp. To clone longer lengths of DNA, lambda phage with lysogeny genes deleted, cosmids, bacterial artificial chromosomes
Plasmid
DNA strand exchange
recombinases, lambda phage integrase (using attP/B recognition sites), differs from the now well-known enzymes such as Cre (from the P1 phage) and FLP (from
Site-specific_recombination
American biologist
is a biologist and geneticist, noted for her pioneering research on lambda phage, a virus that infects bacteria; discovery of the master control gene
Barbara_J._Meyer
American microbiologist and NASA astronaut
Technologies to determine the DNA sequences of mouse, E. coli bacteria, and lambda phage virus. It was a part of the Biomolecule Sequencer experiment, the goal
Kathleen_Rubins
Foods produced from organisms that have had changes introduced into their DNA
into DNA of Simian Virus 40: Circular SV40 DNA Molecules Containing Lambda Phage Genes and the Galactose Operon of Escherichia coli". Proceedings of the
Genetically_modified_food
Cell response to DNA damage
microscopy[citation needed] (top right of image). Induction of lysis in lambda phage Little, John W.; Mount, David W. (May 1982). "The SOS regulatory system
SOS_response
Indian geneticist
microbial genetical genomics, especially the studies on Escherichia coli and Lambda phage as well as on the mutants of Rhizobium. He was a former director of the
Sushil_Kumar_(biologist)
Species of virus
Bacteriophage 186 is often compared to the more extensively studied lambda phage as both their prophages respond to DNA damage in the host, more commonly
Escherichia_virus_186
Lab procedure detecting 5-methylcytosines in DNA
by including an internal control in the sequencing library, such as lambda phage DNA (which is known to be unmethylated) or by aligning bisulfite sequencing
Bisulfite_sequencing
Gram-negative gammaproteobacterium
the passages it lost its O antigen and in 1953 was cured first of its lambda phage (W1485, ATCC 12435; by UV by Joshua Lederberg and colleagues) and then
Escherichia coli in molecular biology
Escherichia_coli_in_molecular_biology
Calendar year
into DNA of Simian Virus 40: Circular SV40 DNA Molecules Containing Lambda Phage Genes and the Galactose Operon of Escherichia coli". Proceedings of the
1972
Set of methods in molecular biology
into DNA of Simian Virus 40: circular SV40 DNA molecules containing lambda phage genes and the galactose operon of Escherichia coli". Proceedings of the
Molecular_cloning
Intermediate DNA structure in viral replication
"[Substrate of a UV-induced repair system providing for W-reactivation of lambda phage]". Genetika (in Russian). 12 (8): 131–8. PMID 1001892. Kunisada, T.;
CccDNA
Animal that has been genetically modified
into DNA of Simian Virus 40: circular SV40 DNA molecules containing lambda phage genes and the galactose operon of Escherichia coli". Proceedings of the
Genetically_modified_animal
Biological particle which transfers genetic material between cells
molecular cloning, a vector is any particle (e.g., plasmids, cosmids, Lambda phages) used as a vehicle to artificially carry a foreign nucleic sequence
Vector_(molecular_biology)
American molecular biologist (1925–2008)
transduction. The research in specialized transduction focused upon lambda phage infection of E. coli. Transduction and specialized transduction explained
Joshua_Lederberg
Biological cell regulation mechanisms
and late phase, using collinear systems regulated by anti-terminators (lambda phage) or splicing modulators (HIV).[citation needed] Gal4 is a transcriptional
Regulation_of_gene_expression
Type of vaccine
into DNA of Simian Virus 40: circular SV40 DNA molecules containing lambda phage genes and the galactose operon of Escherichia coli". Proceedings of the
Viral_vector_vaccine
organisms used in scientific research. Phages (infecting prokaryotes): Escherichia virus Lambda (Phage lambda) Phi X 174, the first DNA genome ever to
List_of_model_organisms
Exodeoxyribonuclease (lambda-induced) (EC 3.1.11.3, lambda exonuclease, phage lambda-induced exonuclease, Escherichia coli exonuclease IV, E. coli exonuclease
Exodeoxyribonuclease (lambda-induced)
Exodeoxyribonuclease_(lambda-induced)
Bacteriophage genome that is integrated into a bacterial cell
A prophage is a bacteriophage (often shortened to "phage") genome that is integrated into the circular bacterial chromosome or exists as an extrachromosomal
Prophage
American geneticist and molecular biologist (born 1930)
could be answered by examining phage particles derived from co-infection of bacteria with genetically marked Lambda phages that were labeled with heavy
Matthew_Meselson
American biologist (1927–2020)
first examples of self-regulation of a gene (cI, the repressor gene of lambda phage) and later did pioneering work on molecular chaperones. Some of the methods
A._Dale_Kaiser
sequence (target site overlap). Filamentous helper phage and the DNA from lambda phage are utilised in phage display. Due to limitations in the size of libraries
Zinc_finger_chimera
Species of virus
prototypic phage for all the speA-carrying phages of Streptococcus pyogenes, meaning that its genome is the prototype for the genomes of all such phages of S
Bacteriophage_T12
Use of viruses as a source of nanoparticles for biomedical purposes
Goff, S (1976). "Construction of hybrid viruses containing SV40 and $lambda; phage DNA segments and their propagation in cultured monkey cells". Cell.
Virus_nanotechnology
Swiss molecular biologist (1919-2011)
Kellenberger took on an increasingly important role in the study of lambda phage and its mutations at the University of Geneva. Her collaboration with
Grete_Kellenberger-Gujer
American biochemist and geneticist
biology of a model bacteriophage (a virus that infects bacteria) known as lambda phage. He was particularly interested in mechanisms of DNA recombination and
Howard_Nash
British molecular biologist
bioscience firm BigDNA, which designs and develops vaccines based on the lambda phage carrying DNA-based vaccines. The Noreen and Kenneth Murray Library was
Noreen_Murray
Mobile genetic elements
representative example of ICE integrases is the integrase encoded by lambda phage. The transfer of an integrated ICE element from the donor to recipient
Integrative and conjugative element
Integrative_and_conjugative_element
InterPro Family
Griffiths AJ, Miller JH, Suzuki DT, Lewontin RC, Gelbart WM (2000). "Lambda phage: a complex of operons". An Introduction to Genetic Analysis. (7th ed
GrpE
prohead of Bacillus subtilis phage φ29. Catalano, C. E.; Cue, D.; Feiss, M. (1995). "Virus DNA packaging: the strategy used by phage λ". Molecular Microbiology
Prohead
into DNA of Simian Virus 40: Circular SV40 DNA Molecules Containing Lambda Phage Genes and the Galactose Operon of Escherichia coli". Proceedings of the
1972_in_science
Fully infectious extracellular virus particle
and minor tail proteins (MTP and mTP), as seen in the Enterobacteria phage lambda. In addition, there may be a tail spike protein (TSP) or tail fiber protein
Virion
one of the most influential founders of bacterial and bacteriophage (Lambda phage) genetics. From 1946 to 1966 Hollaender was the director of the Biology
Alexander_Hollaender
American biophysicist
2008. Englander, S. Walter. X-Radiation Studies on the Lambda Phage and a Method for Measuring Phage Nucleic Acid. Thesis (M.S.)--University of Pittsburgh
S._Walter_Englander
threat to biodiversity. The genetic information can be stored within lambda phage and plasma vectors. The National Institute of Agrobiological Sciences
DNA_bank
Bacteriophage (phage) are viruses of bacteria and arguably are the most numerous "organisms" on Earth. The history of phage study is captured, in part
Phage_monographs
Month of 1972
into DNA of Simian Virus 40: Circular SV40 DNA Molecules Containing Lambda Phage Genes and the Galactose Operon of Escherichia coli. Proceedings of the
October_1972
Enzymes that catalyze DNA formation
synthesis in a living cell was first determined as the rate of phage T4 DNA elongation in phage infected E. coli. During the period of exponential DNA increase
DNA_polymerase
Single-molecule imaging technique
double-stranded DNA (dsDNA) and single-stranded DNA (ssDNA) can be used. Lambda phage DNA is commonly used as a dsDNA substrate because it is commercially
DNA_curtain
Family of repressor proteins in bacteriophage lambda
such as Enterobacteria phage P22 Cro and Bacteriophage 434 Cro, have an all-alpha structure that is thought to be ancestral to lambda Cro, where the fourth
Cro_repressor_family
To model other biological regulatory networks (BRNs) like toy gene, lambda phage (Ahmad and Roux, 2008), Pseudomonas aeruginosa and circadian rhythm.
Kinetic_logic
Scientific research area
Goff, S P (1976). "Construction of Hybrid Viruses Containing Sv40 and Lambda Phage DNA Segments and Their Propagation in Cultured Monkey Cells" (PDF). Cell
Intracellular_delivery
Species of virus
bacterial virus (bacteriophage) that infects Salmonella typhimurium. Like many phages, it has been used in molecular biology to induce mutations in cultured bacteria
Lederbergvirus_P22
biotin-based capture system to select for full length cDNA, a novel lambda phage vector that minimized biases when delivering cDNA into a plasmid, and
FANTOM
Protein-coding gene in the species Homo sapiens
Maruyama IN (October 2000). "Affinity selection of cDNA libraries by lambda phage surface display". Gene. 256 (1–2): 229–236. doi:10.1016/S0378-1119(00)00348-6
ABCA7
LAMBDA PHAGE
LAMBDA PHAGE
Girl/Female
Indian
Dark lipped
Female
Spanish
Feminine form of Spanish Amado, AMADA means "beloved."
Girl/Female
Muslim
Praiseworthy, Praiser of Allah
Surname or Lastname
English
English : habitational name from Lambden in Berwickshire.
Female
Native American
Native American Indian name ALAMEDA means "grove of cottonwood."
Girl/Female
Muslim
Ambitious
Female
Italian
Italian form of English Amber, AMBRA means "amber."
Girl/Female
Indian
Praiseworthy, Praiser of Allah
Girl/Female
Muslim
Soft to touch
Boy/Male
Indian
Jaws.
Girl/Female
Muslim
Dark lipped
Girl/Female
Indian
Soft to touch
Surname or Lastname
English
English : from a pet form of Lamb 1 and 2.English : from an Old Norse personal name Lambi, from lamb ‘lamb’.
Surname or Lastname
English
English : from Middle English lamb, a nickname for a meek and inoffensive person, or a metonymic occupational name for a keeper of lambs. See also Lamm.English : from a short form of the personal name Lambert.Irish : reduced Anglicized form of Gaelic Ó Luain (see Lane 3). MacLysaght comments: ‘The form Lamb(e), which results from a more than usually absurd pseudo-translation (uan ‘lamb’), is now much more numerous than O’Loan itself.’Possibly also a translation of French agneau.
Boy/Male
Hindu
Lord Ganesh, The huge bellied Lord
Girl/Female
Indian
Ambitious
Girl/Female
Muslim
Flame
Female
Greek
(Λαμία) Greek myth name of an evil spirit who abducts and devours children, LAMIA means "large shark." The name means "vampire" in Latin and "fiend" in Arabic.
Girl/Female
Indian
Flame
Girl/Female
Arabic, Indian, Muslim, Pashtun, Sanskrit
Flame; Large; Spacious; Tall; Another Name for Durga and Lakshmi
LAMBDA PHAGE
LAMBDA PHAGE
Girl/Female
Tamil
Cotton
Girl/Female
Indian
Obstinate
Boy/Male
Biblical
A grape, a knot.
Boy/Male
Biblical
Well beloved, amiable.
Boy/Male
Biblical
The pressing; the meditation of God.
Boy/Male
Tamil
Brihadeesh | பà¯à®°à¯€à®¹à®¾à®¤à®¿à®·Â
Lord Shiva
Girl/Female
Tamil
Being near, The Lord Saibaba message
Boy/Male
Bengali, Gujarati, Hindu, Indian, Kannada, Malayalam, Marathi, Telugu
Lord of the Sacrificial Fire; Lord Fo the Sacrificial Fire
Boy/Male
Hindu, Indian
Quite New
Female
English
Variant spelling of French Oriane, possibly ORIANNE means "golden."
LAMBDA PHAGE
LAMBDA PHAGE
LAMBDA PHAGE
LAMBDA PHAGE
LAMBDA PHAGE
pl.
of Lamina
a.
Shaped like the Greek letter lambda (/); as, the lambdoid suture between the occipital and parietal bones of the skull.
n.
The blade of a leaf; the broad, expanded portion of a petal or sepal of a flower.
n.
The name of the Greek letter /, /, corresponding with the English letter L, l.
n.
A lamb.
pl.
of Lamina
v. i.
To bring forth a lamb or lambs, as sheep.
n.
The point of junction of the sagittal and lambdoid sutures of the skull.
n.
Any person who is as innocent or gentle as a lamb.
n.
A thin plate or scale; specif., one of the thin, flat processes composing the vane of a feather.
n.
A viola da gamba.
n.
A thin plate or scale; a layer or coat lying over another; -- said of thin plates or platelike substances, as of bone or minerals.
n.
The lamb's-quarters (Chenopodium album).
a.
Lamed; lame; disabled; impeded.
n.
A thin plate or lamina.
n.
A lamp or candlestick.
imp. & p. p.
of Lamb
p. pr. & vb. n.
of Lamb
n.
A lamb.
n.
A monster capable of assuming a woman's form, who was said to devour human beings or suck their blood; a vampire; a sorceress; a witch.