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Cell response to DNA damage
The SOS response is a global transcriptional response to DNA damage in prokaryotes, in which the cell cycle is arrested and DNA repair mechanisms (error-free
SOS_response
Cellular mechanism
The SOS response is the changes in gene expression in Escherichia coli and other bacteria in response to extensive DNA damage. The prokaryotic SOS system
DNA_repair
changing environment microorganisms were exposed to. The SOS response in E. coli is a response to DNA damage that must be repaired. The normal cell cycle
Adaptive_mutation
Class of enzymes
TLS (translesion DNA synthesis) polymerase in E. coli as part of the SOS response to DNA damage. When DNA is damaged regular DNA synthesis polymerases
DNA_polymerase_V
International Morse code distress signal for help
SOS Audio of SOS in Morse code Problems playing this file? See media help. SOS is a Morse code distress signal ( ▄ ▄ ▄ ▄▄▄ ▄▄▄ ▄▄▄ ▄ ▄ ▄ ), used internationally
SOS
addition of S9 microsomal rat liver extract. The SOS response plays a central role in the response of E. coli to genotoxic compounds because it responds
SOS_chromotest
Bacteriophage that infects Escherichia coli
the SOS response of the cell, as detailed in the section on induction. The former will also be affected by this; a cell undergoing an SOS response will
Lambda_phage
coli-like SOS system for repair of DNA since they code for genes central to the E. coli SOS response such as lexA (regulation of the SOS system) and
Bacterial_stress_response
Prokaryotic protein
sensitivity A) is a transcriptional repressor (EC 3.4.21.88) that represses SOS response genes coding primarily for error-prone DNA polymerases, DNA repair enzymes
LexA_repressor
Topics referred to by the same term
up SOS or sos in Wiktionary, the free dictionary. SOS is the common name of the international Morse code distress signal. SOS may also refer to: Sos, Nagorno-Karabakh
SOS_(disambiguation)
2022 studio album by SZA
SOS is the second studio album by American singer-songwriter SZA. It was released on December 9, 2022, by Top Dawg Entertainment (TDE) and RCA Records
SOS_(SZA_album)
Bacterial DNA damage response pathway
independently of the SOS response. Bacteria such as Escherichia coli exposed to sub-lethal doses of methylation damage activate the Ada response pathway. This
Adaptive_response
Concept in toxicology
The SOS/umu assay test evaluates the ability of a substance to induce DNA damage; it is based on the alterations in the induction of the SOS response due
Genotoxicity
Health and security service firm
International SOS is a health and security service firm. As of 2024, the company takes over 3.2 million assistance calls every year, and has approximately
International_SOS
Indian hip hop duo
2025. Trivedi, Aaryaman (June 26, 2024). "Seedhe Maut Release 6-Minute SOS Response Diss 'TT / Shutdown'". Rolling Stone India. Retrieved June 26, 2025.
Seedhe_Maut
Enzymes that catalyze DNA formation
polymerase V (Pol V) is a Y-family DNA polymerase that is involved in SOS response and translesion synthesis DNA repair mechanisms. Transcription of Pol
DNA_polymerase
American geneticist (1921–2023)
the SOS response until her retirement. The SOS response to DNA damage was a seminal discovery because it was the first coordinated stress response to be
Evelyn_M._Witkin
Biochemical process related to DNA damage
toxin-antitoxin system which is induced by the SOS response in response to DNA damage. IstR sRNA (inhibitor of SOS-induced toxicity by RNA) is a family of non-coding
TisB-IstR toxin-antitoxin system
TisB-IstR_toxin-antitoxin_system
Type of bacteria growth
fluoroquinolones, novobiocin) induce filamentation via the SOS response. The SOS response inhibits septum formation until the DNA can be repaired, this
Filamentation
Biological process
Transcriptional Responses to Ciprofloxacin in Acinetobacter baumannii: Acquired Resistance Alleles Modulate Drug-Induced SOS Response and Prophage Replication"
Mutagenesis
DNA repair protein
heteroduplex formation steps of recombinational repair. In the bacterial SOS response, it functions as a co-protease in the autocatalytic cleavage of the LexA
RecA
Damage in DNA which occurs naturally
damages (called the SOS response in Escherichia coli) has been found in many bacterial species. E. coli RecA, a key enzyme in the SOS response pathway, is the
DNA damage (naturally occurring)
DNA_damage_(naturally_occurring)
Feature of bacterial genomes
integrase was controlled by the bacterial SOS response, thus coupling this adaptive apparatus to the stress response in bacteria. In 2025 two groups found
Integron
Austria-based international children's non-governmental organization
SOS Children's Villages (German: SOS-Kinderdorf) is an independent, non-governmental international organization headquartered in Vienna, Austria. Founded
SOS_Children's_Villages
2006 single by Rihanna
May 2011, and referred to Rihanna and writing "SOS" in his response, saying: I did Rihanna's song “SOS” and it wasn't her first song, but it was her first
SOS_(Rihanna_song)
an overlap between oxidative stress response and other regulatory networks like heat shock response, SOS response. The defenses against deleterious effects
Oxidation_response
Type of physical variation in bacteria
the SOS response. During repair of DNA damage, the SOS response aids bacterial propagation by inhibiting cell division. DNA damage induces the SOS response
Bacterial morphological plasticity
Bacterial_morphological_plasticity
Type of bacteriocin produced by and toxic to some strains of Escherichia coli
the colicin structural gene. The colicin itself is repressed by the SOS response and may be regulated in other ways as well. Retaining the colicin plasmid
Colicin
Spanish computational biologist
primarily on the study of transcription regulatory networks. Working on the SOS response as a model network, Erill developed RCGScanner and later CGB to analyze
Ivan_Erill
Melanin-producing cells of the skin
cells by thymidine dinucleotides: evidence for a p53-mediated mammalian SOS response". Proceedings of the National Academy of Sciences of the United States
Melanocyte
Transfer of genes from unrelated organisms
element (ICE) Bs1 has been reported for its role in the global DNA damage SOS response of the gram positive Bacillus subtilis. Furthermore, it has been linked
Horizontal_gene_transfer
DNA sequence recognized by LexA
SOS box is the operator to which the LexA repressor binds to repress the transcription of SOS-induced proteins. SOS boxes are found near the promoter
SOS_box
Topics referred to by the same term
language of Indonesia Sula people, an ethnic group in Indonesia SulA, an SOS response protein Sula, a 1969 children's novel by Lavinia Derwent, with three
Sula
Technology company
Cove, Simplisafe, SiriusXM and MedicAlert to facilitate emergency response. RapidSOS was founded in 2012 by Michael Martin and Nicholas Horelik to address
RapidSOS
Somatic cells Somatic mutation Somatic mutations Somatostatin SOS box SOS repair SOS response Southern blot Southern blotting Spacer DNA Speciation Speciation
Index_of_genetics_articles
Topics referred to by the same term
de facto global IT and digital skills framework SfiA, a.k.a. SulA, an SOS response protein Science & Futurism with Isaac Arthur This disambiguation page
SFIA
Protein family
includes DNA-damage-inducible protein I (DinI) and related proteins. The SOS response, a set of cellular phenomena exhibited by eubacteria, is initiated by
DinI-like_protein_family
Bacterial toxin-antitoxin system
type I TA system is induced by the bacterial DNA damage response system known as the SOS response system. dinQ, DNA-damage-inducible protein Q produces
DinQ-agrB toxin-antitoxin system
DinQ-agrB_toxin-antitoxin_system
the majority of observed switch events, stressors - such as the cell's SOS response (due to DNA damage) or a change in nutrients - induces the switch. Temperate
Temperateness_(virology)
Biological assay to assess the genotoxic potential of chemical compounds
umuC gene is essentially involved in bacterial mutagenesis through the SOS response. This test uses an operon fusion placing the lac operon (responsible
Umu_Chromotest
Dormant, persistent state of a bacterial population
number of different stress responses such as the SOS response, the envelope stress response, and the starvation response have also been associated with
Persister_cells
Type of organic compound
In addition, polyamine participate in initiating the expression of SOS response of Colicin E7 operon and down-regulate proteins that are essential for
Polyamine
Croatian biologist
with Evelyn M. Witkin set the basis for the discovery of the SOS response. The SOS response hypothesis was put forward by Radman in 1970 in a letter sent
Miroslav_Radman
Antibiotic
toxin-producing Escherichia coli: the role of antibiotics and the bacterial SOS response". Emerging Infectious Diseases. 6 (5): 458–465. doi:10.3201/eid0605.000503
Trimethoprim
American singer-songwriter (born 1989)
SZA her first Grammy Award. SZA's acclaimed and multi-genre second album SOS (2022) became the first by a woman to spend 100 weeks within the Billboard
SZA
American politician (born 1977)
of Vote" (PDF). sos.ca.gov. Sacramento: Secretary of State of California. 2012. p. 107. General election: "Statement of Vote" (PDF). sos.ca.gov. Sacramento:
Adam_Gray
New Zealand abortion service in the 1970s
1980s. It was founded in response to the restrictions imposed by the Contraception, Sterlisation, and Abortion Act 1977. SOS arranged for women from all
Sisters_Overseas_Service
India, incorporating emergency disaster response during natural disasters such as earthquakes and cyclones. SOS Children's Villages India conducts its
SOS_Children's_Villages_India
Biological process
Altuvia S (December 2004). "The small RNA IstR inhibits synthesis of an SOS-induced toxic peptide". Current Biology. 14 (24): 2271–6. Bibcode:2004CBio
Toxin-antitoxin_system
Alteration in the nucleotide sequence of a genome
times been named as adaptive mutagenesis mechanisms, and include the SOS response in bacteria, ectopic intrachromosomal recombination and other chromosomal
Mutation
Conversion of DNA single-stranded gaps
PRR enzymes is regulated by the SOS response in bacteria and may be controlled by the postreplication checkpoint response in eukaryotes. The elucidation
Postreplication_repair
Genus of bacteria
that regulates an SOS response system, probably a system like the well-studied E. coli SOS system that is employed in the response to DNA damage. Ancestors
Prochlorococcus
Type of DNA damage
at sites of pyrimidine dimers. This occurs in prokaryotes through the SOS response to mutagenesis and in eukaryotes through other methods. As thymine–thymine
Pyrimidine_dimer
Klyne-Prelog system Vladimir Prelog Puretic power block Mario Puratić SOS response Miroslav Radman Randić's molecular connectivity index Milan Randić Synthesis
List of Croatian inventions and discoveries
List_of_Croatian_inventions_and_discoveries
1979 single by the Police
island who sends out a message in a bottle to seek love. Having received no response for a year, he despairs, believing that he is destined to be alone. The
Message in a Bottle (The Police song)
Message_in_a_Bottle_(The_Police_song)
Genus of bacteria
that regulates an SOS response system, that is likely similar to the well-studied E. coli SOS system that is employed in the response to DNA damage. Synechococcus
Synechococcus
with a response time of 48 hours. SOS Amitié Internet is an organization founded under the 1901 law and affiliated with the Federation SOS Amitié France
SOS_Amitié
1975 single by Retta Young
"Sending Out An S.O.S." is a 1975 song for singer Retta Young. It charted in the US on the Billboard and Cash Box charts. It charted also in the UK where
Sending_Out_An_S.O.S.
Special mission military aircraft
North Carolina, (redesignated 318th SOS in 1971 and 8th SOS in 1974). The 15th SOS was redesignated the 90th SOS on 23 October 1970, relocated to Cam
Lockheed_MC-130
School shooting in Örebro, Sweden
for the victims. The ambassador of Bosnia and Herzegovina to Sweden Bojan Sosic laid flowers outside of the school in honor of the Bosnian victim of the
Örebro_school_shooting
Species of virus
prophages respond to DNA damage in the host, more commonly known as the SOS response, even though the two bacteriophages are evolutionarily distinct. International
Escherichia_virus_186
DNA mutation involving an increase in number of trinucleotide repeats
(November 2005). "Roles of the Escherichia coli RecA Protein and the Global SOS Response in Effecting DNA Polymerase Selection In Vivo". Journal of Bacteriology
Trinucleotide repeat expansion
Trinucleotide_repeat_expansion
Biological process
inactivation by AMPylation leads to the activation of SOS response, which is the cellular response to DNA damage. The activity of FicT AMPylation is reversible
Adenylylation
American molecular biologist, biochemist and geneticist
interested in factors controlling fidelity of DNA replication and the SOS response caused by DNA damage. He spent a sabbatical year in 1981–1982 in Arthur
Harrison_Echols
DNA sequence whose position in the genome is variable
the ICEBs1 is well-characterized for its role in the global DNA damage SOS response of Bacillus subtilis and also its potential link to the radiation and
Mobile_genetic_elements
Satellite communications device brand
coverage. All inReach devices feature texting, remote location tracking, and SOS via satellite. Newer devices feature Weather. Some devices have offline maps
Garmin_inReach
"The small 6C RNA of Corynebacterium glutamicum is involved in the SOS response". RNA Biol. 13 (9): 848–60. doi:10.1080/15476286.2016.1205776. PMC 5014011
RNA_motif
2020 Indian Bengali action-thriller film
SOS Kolkata is a 2020 Indian Bengali-language action thriller film written and directed by Anshuman Pratyush and produced by Jarek Entertainment and Pratyush
SOS_Kolkata
19th episode of the 2nd season of Lost
"S.O.S." is the 19th episode of the second season of Lost and the 44th episode overall. The episode was directed by Eric Laneuville, and written by Steven
S.O.S._(Lost)
Japanese politician (born 1974)
which was formed by Hatoyama. He also became the leader of the Food SOS Response Project, which was launched by the Consumer Affairs Agency to address
Kenta_Izumi
navigating umbrella to attract a star. But instead of a star, Nobita catches an SOS capsule and helps the person stuck in space. He gets a video game in return
List of Doraemon (1979 TV series) episodes (1987–2005)
List_of_Doraemon_(1979_TV_series)_episodes_(1987–2005)
Class of enzymes
mispairings. This amount can be increased upon the inducement of the SOS response, which upregulates the polB gene so the amount of Polymerase II increases
DNA_polymerase_II
involved in stress response regulation. They are expressed under stress conditions such as cold shock, iron depletion, onset of the SOS response and sugar stress
Bacterial_small_RNA
2003 film by Masaaki Tezuka
Godzilla: Tokyo S.O.S. (ゴジラ×モスラ×メカゴジラ 東京SOS, Gojira Mosura Mekagojira Tōkyō Esu-Ō-Esu) is a 2003 Japanese kaiju film and the direct sequel to Godzilla
Godzilla:_Tokyo_S.O.S.
American emeritus microbiologist
Jordi; Penadés, José R. (April 2006). "β-Lactam Antibiotics Induce the SOS Response and Horizontal Transfer of Virulence Factors in Staphylococcus aureus"
Richard_P._Novick
American geneticist
the search for RNA viruses by Tim Loeb (1961), to the discovery of the SOS response in bacteria by Miroslav Radman (1976), and to the development of techniques
Maurice_Sanford_Fox
American molecular biologist
career, and identified a secondary DNA damage response that is independent of the well-documented SOS response. Lovett identified many of the enzymes involves
Susan_Lovett
Non-profit network of autonomous addiction recovery groups
Secular Organizations for Sobriety (SOS), also known as Save Our Selves, was a non-profit network of autonomous addiction recovery groups. The program
Secular Organizations for Sobriety
Secular_Organizations_for_Sobriety
2024 song by SZA
song by American singer-songwriter SZA from SOS Deluxe: Lana (2024), the reissue of her second studio album SOS (2022). It is an R&B love song, with a musical
Diamond_Boy_(DTM)
US nonprofit organization
Boat People SOS (BPSOS) is a 501(c)(3) nonprofit organization devoted to Vietnamese-American civic and political activism. It is headquartered in Falls
Boat_People_SOS
2023 American film
SOS - The San Onofre Syndrome: Nuclear Power’s Legacy is a documentary film that investigates the management of radioactive waste at the San Onofre Nuclear
SOS:_The_San_Onofre_Syndrome
Class of enzyme that catalyzes the degradation of RNA
plant origin, which modulates SOS responses in bacteria, for a response to the stress of DNA damage by activation of the SOS mechanism by the RecA/LexA dependent
Ribonuclease
American christian music superduo
Records and has been active since 2025. They released their debut single, "SOS" on March 27, 2026. Their debut studio album, Dawn Patrol, was released on
Party_Wave_(band)
studied the chemistry of DNA repair and the mechanisms of the cellular SOS response to DNA damage. She was particularly intrigued by the life cycle of the
Nancy_Craig
Young adult novel series by Colin Bateman
The SOS Adventures series is a trilogy of young adult novels written by Northern Irish author Colin Bateman, released between June 2010 and March 2011
SOS_Adventures
Irish presenter and media personality (born 1985)
announced as the host of a new virtual reality show called Send Nudes: Body SOS, about peoples' decisions relating to planned plastic surgery, which ran
Vogue_Williams
voyage before retirement, which seems uneventful, until they pick up on an SOS from a capsized fisher boat. The captain orders his ship to the rescue, but
List_of_Candy_Candy_episodes
Swiss biologist (1901–1968)
system. The induction of DNA damage-response genes in bacteria has come to be known as the SOS response. This response includes DNA damage inducible mutagenesis
Jean_Weigle
American politician (born 1980)
original on February 13, 2023. Retrieved June 25, 2025. https://elections.cdn.sos.ca.gov/sov/2024-general/sov/25-us-rep-congress.pdf (PDF). California Secretary
Eric_Swalwell
American politician (born 1973)
sos.ca.gov. Sacramento: Secretary of State of California. 2010. p. 12. Retrieved November 13, 2022. Primary election: "Statement of Vote" (PDF). sos.ca
Alex_Padilla
Acronym invented to fit an existing word
backronym of "council-housed and violent". Similarly, the distress signal SOS is often believed to be an abbreviation for "save our ship" or "save our
Backronym
Category 5 Atlantic hurricane in 2017
Daniella Silva and Sandra Lilley (September 27, 2017). "Mayor Issues 'S.O.S.' as Puerto Ricans Scramble to Help Most Vulnerable". NBC News. Archived
Hurricane_Maria
gives up on waiting and goes on a date with Charlie. Michelle gets Hunter's SOS text and frees Hunter and Emily from the closet. In confessional, Emily says
List of The Next Step episodes
List_of_The_Next_Step_episodes
Mid-1900s informal network of biologists
inducible nature of DNA damage-response genes in bacteria, a phenomenon that has come to be known as the SOS response. This response includes DNA damage-inducible
Phage_group
Free online crowdsourced encyclopedia
for Schools", the Wikipedia series of CDs / DVDs produced by Wikipedia and SOS Children, is a free selection from Wikipedia designed for education towards
Wikipedia
RNA family
antitoxin is more stable than the SymE toxin. Following DNA damage, the SOS response represses transcription of SymR RNA, allowing SymE toxin to degrade potentially
SymE-SymR toxin-antitoxin system
SymE-SymR_toxin-antitoxin_system
abundance by improving Na+ efflux from its cells through SOS pathway Two different paths in the SOS pathway can activate SOS1, a molecule that causes sodium
Arabidopsis thaliana responses to salinity
Arabidopsis_thaliana_responses_to_salinity
South African hip hop duo
the music video for their song "Fok Julle Naaiers" and, in response to a negative review of SOS by South African journalist Chris Roper, included his personal
Die_Antwoord
2024 bridge collapse near Baltimore, Maryland, US
2024. Retrieved March 27, 2024. ""As a result...": Biden's shout-out for SOS by Indian crew on ship". NDTV.com. Archived from the original on March 27
Francis Scott Key Bridge collapse
Francis_Scott_Key_Bridge_collapse
2023 single by SZA
singer-songwriter SZA, and the sixth single from her second studio album, SOS (2022). It is an R&B song with a midtempo rhythm, featuring an instrumental
Snooze_(SZA_song)
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