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GJB6

  • GJB6

    • Protein-coding gene in the species Homo sapiens

    Gap junction beta-6 protein (GJB6), also known as connexin 30 (Cx30) — is a protein that in humans is encoded by the GJB6 gene. Connexin 30 (Cx30) is one

    GJB6

    GJB6

    GJB6

  • Clouston's hidrotic ectodermal dysplasia

    • Medical condition affecting scalp hair

    dysplasia is a medical condition caused by mutations in a connexin gene, GJB6 or connexin-30, characterized by scalp hair that is wiry, brittle, and pale

    Clouston's hidrotic ectodermal dysplasia

    Clouston's_hidrotic_ectodermal_dysplasia

  • Ectodermal dysplasia

    • Group of genetic conditions affecting the embryonic ectoderm

    associated with PKP1. Clouston's hidrotic ectodermal dysplasia is associated with GJB6. Naegeli syndrome/Dermatopathia pigmentosa reticulariss is associated with

    Ectodermal dysplasia

    Ectodermal dysplasia

    Ectodermal_dysplasia

  • Nonsyndromic deafness

    • Medical condition

    the ACTG1, CABP2, CDH23, CLDN14, COCH, COL11A2, DFNA5, ESPN, EYA4, GJB2, GJB6, KCNQ4, MYO15A, MYO6, MYO7A, OTOF, PCDH15, POU3F4, SLC26A4, STRC, TECTA,

    Nonsyndromic deafness

    Nonsyndromic_deafness

  • Chromosome 13

    • Human chromosome

    factor receptor 1) GJB2: gap junction protein, beta 2, 26kDa (connexin 26) GJB6: gap junction protein, beta 6 (connexin 30) Glypican 5: encoding protein

    Chromosome 13

    Chromosome 13

    Chromosome_13

  • Membrane channel

    • Connexin A GJA1 GJA3 GJA4 GJA5 GJA8 GJA9 GJA10 B GJB1 GJB2 GJB3 GJB4 GJB5 GJB6 GJB7 C GJC1 GJC2 GJC3 D GJD2 GJD3 GJD4 Innexin By gating mechanism Ion channel

    Membrane channel

    Membrane_channel

  • CACNA2D1

    • Protein-coding gene in humans

    Connexin A GJA1 GJA3 GJA4 GJA5 GJA8 GJA9 GJA10 B GJB1 GJB2 GJB3 GJB4 GJB5 GJB6 GJB7 C GJC1 GJC2 GJC3 D GJD2 GJD3 GJD4 Innexin By gating mechanism Ion channel

    CACNA2D1

    CACNA2D1

    CACNA2D1

  • KCNH5

    • Protein-coding gene in the species Homo sapiens

    Connexin A GJA1 GJA3 GJA4 GJA5 GJA8 GJA9 GJA10 B GJB1 GJB2 GJB3 GJB4 GJB5 GJB6 GJB7 C GJC1 GJC2 GJC3 D GJD2 GJD3 GJD4 Innexin By gating mechanism Ion channel

    KCNH5

    KCNH5

    KCNH5

  • KCNU1

    • Protein-coding gene in the species Homo sapiens

    Connexin A GJA1 GJA3 GJA4 GJA5 GJA8 GJA9 GJA10 B GJB1 GJB2 GJB3 GJB4 GJB5 GJB6 GJB7 C GJC1 GJC2 GJC3 D GJD2 GJD3 GJD4 Innexin By gating mechanism Ion channel

    KCNU1

    KCNU1

    KCNU1

  • KCNK10

    • Protein-coding gene in the species Homo sapiens

    Connexin A GJA1 GJA3 GJA4 GJA5 GJA8 GJA9 GJA10 B GJB1 GJB2 GJB3 GJB4 GJB5 GJB6 GJB7 C GJC1 GJC2 GJC3 D GJD2 GJD3 GJD4 Innexin By gating mechanism Ion channel

    KCNK10

    KCNK10

    KCNK10

  • KCNK18

    • Protein-coding gene in the species Homo sapiens

    Connexin A GJA1 GJA3 GJA4 GJA5 GJA8 GJA9 GJA10 B GJB1 GJB2 GJB3 GJB4 GJB5 GJB6 GJB7 C GJC1 GJC2 GJC3 D GJD2 GJD3 GJD4 Innexin By gating mechanism Ion channel

    KCNK18

    KCNK18

    KCNK18

  • Ion channel

    • Pore-forming membrane protein

    Connexin A GJA1 GJA3 GJA4 GJA5 GJA8 GJA9 GJA10 B GJB1 GJB2 GJB3 GJB4 GJB5 GJB6 GJB7 C GJC1 GJC2 GJC3 D GJD2 GJD3 GJD4 Innexin By gating mechanism Ion channel

    Ion channel

    Ion channel

    Ion_channel

  • CLIC4

    • Protein-coding gene in the species Homo sapiens

    Connexin A GJA1 GJA3 GJA4 GJA5 GJA8 GJA9 GJA10 B GJB1 GJB2 GJB3 GJB4 GJB5 GJB6 GJB7 C GJC1 GJC2 GJC3 D GJD2 GJD3 GJD4 Innexin By gating mechanism Ion channel

    CLIC4

    CLIC4

    CLIC4

  • Calcium channel, voltage-dependent, T type, alpha 1H subunit

    • Protein found in humans

    Connexin A GJA1 GJA3 GJA4 GJA5 GJA8 GJA9 GJA10 B GJB1 GJB2 GJB3 GJB4 GJB5 GJB6 GJB7 C GJC1 GJC2 GJC3 D GJD2 GJD3 GJD4 Innexin By gating mechanism Ion channel

    Calcium channel, voltage-dependent, T type, alpha 1H subunit

    Calcium channel, voltage-dependent, T type, alpha 1H subunit

    Calcium_channel,_voltage-dependent,_T_type,_alpha_1H_subunit

  • GJC1

    • Protein-coding gene in the species Homo sapiens

    Connexin A GJA1 GJA3 GJA4 GJA5 GJA8 GJA9 GJA10 B GJB1 GJB2 GJB3 GJB4 GJB5 GJB6 GJB7 C GJC1 GJC2 GJC3 D GJD2 GJD3 GJD4 Innexin By gating mechanism Ion channel

    GJC1

    GJC1

    GJC1

  • TRPM

    • Family of transport proteins

    Connexin A GJA1 GJA3 GJA4 GJA5 GJA8 GJA9 GJA10 B GJB1 GJB2 GJB3 GJB4 GJB5 GJB6 GJB7 C GJC1 GJC2 GJC3 D GJD2 GJD3 GJD4 Innexin By gating mechanism Ion channel

    TRPM

    TRPM

  • KCNK3

    • Protein-coding gene in the species Homo sapiens

    Connexin A GJA1 GJA3 GJA4 GJA5 GJA8 GJA9 GJA10 B GJB1 GJB2 GJB3 GJB4 GJB5 GJB6 GJB7 C GJC1 GJC2 GJC3 D GJD2 GJD3 GJD4 Innexin By gating mechanism Ion channel

    KCNK3

    KCNK3

    KCNK3

  • Ryanodine receptor 2

    • Transport protein and coding gene in humans

    Connexin A GJA1 GJA3 GJA4 GJA5 GJA8 GJA9 GJA10 B GJB1 GJB2 GJB3 GJB4 GJB5 GJB6 GJB7 C GJC1 GJC2 GJC3 D GJD2 GJD3 GJD4 Innexin By gating mechanism Ion channel

    Ryanodine receptor 2

    Ryanodine receptor 2

    Ryanodine_receptor_2

  • TPCN2

    • Protein-coding gene in the species Homo sapiens

    Connexin A GJA1 GJA3 GJA4 GJA5 GJA8 GJA9 GJA10 B GJB1 GJB2 GJB3 GJB4 GJB5 GJB6 GJB7 C GJC1 GJC2 GJC3 D GJD2 GJD3 GJD4 Innexin By gating mechanism Ion channel

    TPCN2

    TPCN2

    TPCN2

  • Aquaporin-7

    • Protein-coding gene in the species Homo sapiens

    Connexin A GJA1 GJA3 GJA4 GJA5 GJA8 GJA9 GJA10 B GJB1 GJB2 GJB3 GJB4 GJB5 GJB6 GJB7 C GJC1 GJC2 GJC3 D GJD2 GJD3 GJD4 Innexin By gating mechanism Ion channel

    Aquaporin-7

    Aquaporin-7

    Aquaporin-7

  • R-type calcium channel

    • Protein family

    Connexin A GJA1 GJA3 GJA4 GJA5 GJA8 GJA9 GJA10 B GJB1 GJB2 GJB3 GJB4 GJB5 GJB6 GJB7 C GJC1 GJC2 GJC3 D GJD2 GJD3 GJD4 Innexin By gating mechanism Ion channel

    R-type calcium channel

    R-type_calcium_channel

  • KCNQ1

    • Protein-coding gene in the species Homo sapiens

    Connexin A GJA1 GJA3 GJA4 GJA5 GJA8 GJA9 GJA10 B GJB1 GJB2 GJB3 GJB4 GJB5 GJB6 GJB7 C GJC1 GJC2 GJC3 D GJD2 GJD3 GJD4 Innexin By gating mechanism Ion channel

    KCNQ1

    KCNQ1

    KCNQ1

  • CLNS1A

    • Protein-coding gene in humans

    Connexin A GJA1 GJA3 GJA4 GJA5 GJA8 GJA9 GJA10 B GJB1 GJB2 GJB3 GJB4 GJB5 GJB6 GJB7 C GJC1 GJC2 GJC3 D GJD2 GJD3 GJD4 Innexin By gating mechanism Ion channel

    CLNS1A

    CLNS1A

    CLNS1A

  • KCNF1

    • Protein-coding gene in the species Homo sapiens

    Connexin A GJA1 GJA3 GJA4 GJA5 GJA8 GJA9 GJA10 B GJB1 GJB2 GJB3 GJB4 GJB5 GJB6 GJB7 C GJC1 GJC2 GJC3 D GJD2 GJD3 GJD4 Innexin By gating mechanism Ion channel

    KCNF1

    KCNF1

    KCNF1

  • KCNN1

    • Protein-coding gene in the species Homo sapiens

    Connexin A GJA1 GJA3 GJA4 GJA5 GJA8 GJA9 GJA10 B GJB1 GJB2 GJB3 GJB4 GJB5 GJB6 GJB7 C GJC1 GJC2 GJC3 D GJD2 GJD3 GJD4 Innexin By gating mechanism Ion channel

    KCNN1

    KCNN1

    KCNN1

  • CACNA1G

    • Protein-coding gene in humans

    Connexin A GJA1 GJA3 GJA4 GJA5 GJA8 GJA9 GJA10 B GJB1 GJB2 GJB3 GJB4 GJB5 GJB6 GJB7 C GJC1 GJC2 GJC3 D GJD2 GJD3 GJD4 Innexin By gating mechanism Ion channel

    CACNA1G

    CACNA1G

    CACNA1G

  • Medical genetics of Jews

    • Autosomal recessive conditions that affect ethnic Jews more frequently

    deafness Neurology, otorhinolaryngology, audiology Autosomal recessive GJB2 or GJB6 1/25 Cystic fibrosis Pulmonology, hepatology Autosomal recessive CFTR 1/25

    Medical genetics of Jews

    Medical_genetics_of_Jews

  • Gap junction protein

    • 3, gap junction beta-4 protein GJB5, Cx31.1, gap junction beta-5 protein GJB6, Cx30, gap junction beta-6 protein GJB7, Cx25, gap junction beta-7 protein

    Gap junction protein

    Gap_junction_protein

  • Calcium channel

    • Ion channel complex through which calcium ions pass

    Connexin A GJA1 GJA3 GJA4 GJA5 GJA8 GJA9 GJA10 B GJB1 GJB2 GJB3 GJB4 GJB5 GJB6 GJB7 C GJC1 GJC2 GJC3 D GJD2 GJD3 GJD4 Innexin By gating mechanism Ion channel

    Calcium channel

    Calcium_channel

  • Acid-sensing ion channel

    • Class of transport proteins

    Connexin A GJA1 GJA3 GJA4 GJA5 GJA8 GJA9 GJA10 B GJB1 GJB2 GJB3 GJB4 GJB5 GJB6 GJB7 C GJC1 GJC2 GJC3 D GJD2 GJD3 GJD4 Innexin By gating mechanism Ion channel

    Acid-sensing ion channel

    Acid-sensing ion channel

    Acid-sensing_ion_channel

  • Voltage-gated calcium channel

    • Group of voltage-gated ion channels permeable to Ca2+

    Connexin A GJA1 GJA3 GJA4 GJA5 GJA8 GJA9 GJA10 B GJB1 GJB2 GJB3 GJB4 GJB5 GJB6 GJB7 C GJC1 GJC2 GJC3 D GJD2 GJD3 GJD4 Innexin By gating mechanism Ion channel

    Voltage-gated calcium channel

    Voltage-gated_calcium_channel

  • Ligand-gated ion channel

    • Type of ion channel transmembrane protein

    Connexin A GJA1 GJA3 GJA4 GJA5 GJA8 GJA9 GJA10 B GJB1 GJB2 GJB3 GJB4 GJB5 GJB6 GJB7 C GJC1 GJC2 GJC3 D GJD2 GJD3 GJD4 Innexin By gating mechanism Ion channel

    Ligand-gated ion channel

    Ligand-gated ion channel

    Ligand-gated_ion_channel

  • L-type calcium channel

    • Family of transport proteins

    Connexin A GJA1 GJA3 GJA4 GJA5 GJA8 GJA9 GJA10 B GJB1 GJB2 GJB3 GJB4 GJB5 GJB6 GJB7 C GJC1 GJC2 GJC3 D GJD2 GJD3 GJD4 Innexin By gating mechanism Ion channel

    L-type calcium channel

    L-type calcium channel

    L-type_calcium_channel

  • List of human protein-coding genes 3

    • HGNC:4285; O75712 6260 GJB4 HGNC:4286; Q9NTQ9 6261 GJB5 HGNC:4287; O95377 6262 GJB6 HGNC:4288; O95452 6263 GJB7 HGNC:16690; Q6PEY0 6264 GJC1 HGNC:4280; P36383

    List of human protein-coding genes 3

    List_of_human_protein-coding_genes_3

  • Membrane transport protein

    • Membrane protein involved in transportation

    Connexin A GJA1 GJA3 GJA4 GJA5 GJA8 GJA9 GJA10 B GJB1 GJB2 GJB3 GJB4 GJB5 GJB6 GJB7 C GJC1 GJC2 GJC3 D GJD2 GJD3 GJD4 Innexin By gating mechanism Ion channel

    Membrane transport protein

    Membrane_transport_protein

  • Aquaporin

    • Water channel protein in cell membranes

    Connexin A GJA1 GJA3 GJA4 GJA5 GJA8 GJA9 GJA10 B GJB1 GJB2 GJB3 GJB4 GJB5 GJB6 GJB7 C GJC1 GJC2 GJC3 D GJD2 GJD3 GJD4 Innexin By gating mechanism Ion channel

    Aquaporin

    Aquaporin

    Aquaporin

  • TRPV1

    • Human protein for regulating body temperature

    Connexin A GJA1 GJA3 GJA4 GJA5 GJA8 GJA9 GJA10 B GJB1 GJB2 GJB3 GJB4 GJB5 GJB6 GJB7 C GJC1 GJC2 GJC3 D GJD2 GJD3 GJD4 Innexin By gating mechanism Ion channel

    TRPV1

    TRPV1

    TRPV1

  • Voltage-gated ion channel

    • Type of ion channel transmembrane protein

    Connexin A GJA1 GJA3 GJA4 GJA5 GJA8 GJA9 GJA10 B GJB1 GJB2 GJB3 GJB4 GJB5 GJB6 GJB7 C GJC1 GJC2 GJC3 D GJD2 GJD3 GJD4 Innexin By gating mechanism Ion channel

    Voltage-gated ion channel

    Voltage-gated ion channel

    Voltage-gated_ion_channel

  • KCNH2

    • Mammalian protein found in humans

    Connexin A GJA1 GJA3 GJA4 GJA5 GJA8 GJA9 GJA10 B GJB1 GJB2 GJB3 GJB4 GJB5 GJB6 GJB7 C GJC1 GJC2 GJC3 D GJD2 GJD3 GJD4 Innexin By gating mechanism Ion channel

    KCNH2

    KCNH2

    KCNH2

  • Aquaporin-4

    • Protein-coding gene in the species Homo sapiens

    Connexin A GJA1 GJA3 GJA4 GJA5 GJA8 GJA9 GJA10 B GJB1 GJB2 GJB3 GJB4 GJB5 GJB6 GJB7 C GJC1 GJC2 GJC3 D GJD2 GJD3 GJD4 Innexin By gating mechanism Ion channel

    Aquaporin-4

    Aquaporin-4

    Aquaporin-4

  • Pacemaker current

    • Electric current in the heart

    Connexin A GJA1 GJA3 GJA4 GJA5 GJA8 GJA9 GJA10 B GJB1 GJB2 GJB3 GJB4 GJB5 GJB6 GJB7 C GJC1 GJC2 GJC3 D GJD2 GJD3 GJD4 Innexin By gating mechanism Ion channel

    Pacemaker current

    Pacemaker_current

  • Inward-rectifier potassium channel

    • Group of transmembrane proteins that passively transport potassium ions

    Connexin A GJA1 GJA3 GJA4 GJA5 GJA8 GJA9 GJA10 B GJB1 GJB2 GJB3 GJB4 GJB5 GJB6 GJB7 C GJC1 GJC2 GJC3 D GJD2 GJD3 GJD4 Innexin By gating mechanism Ion channel

    Inward-rectifier potassium channel

    Inward-rectifier potassium channel

    Inward-rectifier_potassium_channel

  • Shapiro–Senapathy algorithm

    • Bibiana; Elgoyhen, Ana Belén; Dalamón, Viviana (21 October 2020). "GJB2 and GJB6 Genetic Variant Curation in an Argentinean Non-Syndromic Hearing-Impaired

    Shapiro–Senapathy algorithm

    Shapiro–Senapathy algorithm

    Shapiro–Senapathy_algorithm

  • Gap junction

    • Cell-cell junction composed of innexins or connexins

    Connexin A GJA1 GJA3 GJA4 GJA5 GJA8 GJA9 GJA10 B GJB1 GJB2 GJB3 GJB4 GJB5 GJB6 GJB7 C GJC1 GJC2 GJC3 D GJD2 GJD3 GJD4 Innexin By gating mechanism Ion channel

    Gap junction

    Gap junction

    Gap_junction

  • Sodium channel

    • Transmembrane protein allowing sodium ions in and out

    Connexin A GJA1 GJA3 GJA4 GJA5 GJA8 GJA9 GJA10 B GJB1 GJB2 GJB3 GJB4 GJB5 GJB6 GJB7 C GJC1 GJC2 GJC3 D GJD2 GJD3 GJD4 Innexin By gating mechanism Ion channel

    Sodium channel

    Sodium channel

    Sodium_channel

  • Voltage-gated potassium channel

    • Class of transport proteins

    Connexin A GJA1 GJA3 GJA4 GJA5 GJA8 GJA9 GJA10 B GJB1 GJB2 GJB3 GJB4 GJB5 GJB6 GJB7 C GJC1 GJC2 GJC3 D GJD2 GJD3 GJD4 Innexin By gating mechanism Ion channel

    Voltage-gated potassium channel

    Voltage-gated potassium channel

    Voltage-gated_potassium_channel

  • Voltage-gated sodium channel

    • Family of transport proteins

    Connexin A GJA1 GJA3 GJA4 GJA5 GJA8 GJA9 GJA10 B GJB1 GJB2 GJB3 GJB4 GJB5 GJB6 GJB7 C GJC1 GJC2 GJC3 D GJD2 GJD3 GJD4 Innexin By gating mechanism Ion channel

    Voltage-gated sodium channel

    Voltage-gated_sodium_channel

  • KCNK2

    • Protein-coding gene in the species Homo sapiens

    Connexin A GJA1 GJA3 GJA4 GJA5 GJA8 GJA9 GJA10 B GJB1 GJB2 GJB3 GJB4 GJB5 GJB6 GJB7 C GJC1 GJC2 GJC3 D GJD2 GJD3 GJD4 Innexin By gating mechanism Ion channel

    KCNK2

    KCNK2

    KCNK2

  • Ryanodine receptor

    • Class of intracellular transport proteins

    Connexin A GJA1 GJA3 GJA4 GJA5 GJA8 GJA9 GJA10 B GJB1 GJB2 GJB3 GJB4 GJB5 GJB6 GJB7 C GJC1 GJC2 GJC3 D GJD2 GJD3 GJD4 Innexin By gating mechanism Ion channel

    Ryanodine receptor

    Ryanodine receptor

    Ryanodine_receptor

  • TRPM8

    • Protein-coding gene in humans

    Connexin A GJA1 GJA3 GJA4 GJA5 GJA8 GJA9 GJA10 B GJB1 GJB2 GJB3 GJB4 GJB5 GJB6 GJB7 C GJC1 GJC2 GJC3 D GJD2 GJD3 GJD4 Innexin By gating mechanism Ion channel

    TRPM8

    TRPM8

    TRPM8

  • TRPA1

    • Protein and coding gene in humans

    Connexin A GJA1 GJA3 GJA4 GJA5 GJA8 GJA9 GJA10 B GJB1 GJB2 GJB3 GJB4 GJB5 GJB6 GJB7 C GJC1 GJC2 GJC3 D GJD2 GJD3 GJD4 Innexin By gating mechanism Ion channel

    TRPA1

    TRPA1

    TRPA1

  • Potassium channel

    • Ion channel that selectively passes K+

    Connexin A GJA1 GJA3 GJA4 GJA5 GJA8 GJA9 GJA10 B GJB1 GJB2 GJB3 GJB4 GJB5 GJB6 GJB7 C GJC1 GJC2 GJC3 D GJD2 GJD3 GJD4 Innexin By gating mechanism Ion channel

    Potassium channel

    Potassium channel

    Potassium_channel

  • Cystic fibrosis transmembrane conductance regulator

    • Mammalian protein found in humans

    Connexin A GJA1 GJA3 GJA4 GJA5 GJA8 GJA9 GJA10 B GJB1 GJB2 GJB3 GJB4 GJB5 GJB6 GJB7 C GJC1 GJC2 GJC3 D GJD2 GJD3 GJD4 Innexin By gating mechanism Ion channel

    Cystic fibrosis transmembrane conductance regulator

    Cystic fibrosis transmembrane conductance regulator

    Cystic_fibrosis_transmembrane_conductance_regulator

  • Transient receptor potential channel

    • Class of transport proteins

    Connexin A GJA1 GJA3 GJA4 GJA5 GJA8 GJA9 GJA10 B GJB1 GJB2 GJB3 GJB4 GJB5 GJB6 GJB7 C GJC1 GJC2 GJC3 D GJD2 GJD3 GJD4 Innexin By gating mechanism Ion channel

    Transient receptor potential channel

    Transient_receptor_potential_channel

  • Nav1.8

    • Protein-coding gene in the species Homo sapiens

    Connexin A GJA1 GJA3 GJA4 GJA5 GJA8 GJA9 GJA10 B GJB1 GJB2 GJB3 GJB4 GJB5 GJB6 GJB7 C GJC1 GJC2 GJC3 D GJD2 GJD3 GJD4 Innexin By gating mechanism Ion channel

    Nav1.8

    Nav1.8

    Nav1.8

  • Inositol trisphosphate receptor

    • Class of transport proteins

    Connexin A GJA1 GJA3 GJA4 GJA5 GJA8 GJA9 GJA10 B GJB1 GJB2 GJB3 GJB4 GJB5 GJB6 GJB7 C GJC1 GJC2 GJC3 D GJD2 GJD3 GJD4 Innexin By gating mechanism Ion channel

    Inositol trisphosphate receptor

    Inositol trisphosphate receptor

    Inositol_trisphosphate_receptor

  • N-type calcium channel

    • Protein family

    Connexin A GJA1 GJA3 GJA4 GJA5 GJA8 GJA9 GJA10 B GJB1 GJB2 GJB3 GJB4 GJB5 GJB6 GJB7 C GJC1 GJC2 GJC3 D GJD2 GJD3 GJD4 Innexin By gating mechanism Ion channel

    N-type calcium channel

    N-type calcium channel

    N-type_calcium_channel

  • BK channel

    • Family of transport proteins

    Connexin A GJA1 GJA3 GJA4 GJA5 GJA8 GJA9 GJA10 B GJB1 GJB2 GJB3 GJB4 GJB5 GJB6 GJB7 C GJC1 GJC2 GJC3 D GJD2 GJD3 GJD4 Innexin By gating mechanism Ion channel

    BK channel

    BK channel

    BK_channel

  • Connexin

    • Group of proteins which form the intermembrane channels of gap junctions

    Can be associated with Erythrokeratodermia variabilis. Cx31.1 GJB5 Cx30 GJB6 Mutated in Clouston syndrome (hidrotic ectodermal dysplasia) Cx25 GJB7 Cx45

    Connexin

    Connexin

    Connexin

  • SK channel

    • Protein subfamily of calcium-activated potassium channels

    Connexin A GJA1 GJA3 GJA4 GJA5 GJA8 GJA9 GJA10 B GJB1 GJB2 GJB3 GJB4 GJB5 GJB6 GJB7 C GJC1 GJC2 GJC3 D GJD2 GJD3 GJD4 Innexin By gating mechanism Ion channel

    SK channel

    SK channel

    SK_channel

  • KCNH1

    • Protein-coding gene in the species Homo sapiens

    Connexin A GJA1 GJA3 GJA4 GJA5 GJA8 GJA9 GJA10 B GJB1 GJB2 GJB3 GJB4 GJB5 GJB6 GJB7 C GJC1 GJC2 GJC3 D GJD2 GJD3 GJD4 Innexin By gating mechanism Ion channel

    KCNH1

    KCNH1

    KCNH1

  • Voltage-dependent anion channel

    • Class of porin ion channels in the outer mitochondrial membrane

    Connexin A GJA1 GJA3 GJA4 GJA5 GJA8 GJA9 GJA10 B GJB1 GJB2 GJB3 GJB4 GJB5 GJB6 GJB7 C GJC1 GJC2 GJC3 D GJD2 GJD3 GJD4 Innexin By gating mechanism Ion channel

    Voltage-dependent anion channel

    Voltage-dependent anion channel

    Voltage-dependent_anion_channel

  • HCN channel

    • Intermembrane proteins

    Connexin A GJA1 GJA3 GJA4 GJA5 GJA8 GJA9 GJA10 B GJB1 GJB2 GJB3 GJB4 GJB5 GJB6 GJB7 C GJC1 GJC2 GJC3 D GJD2 GJD3 GJD4 Innexin By gating mechanism Ion channel

    HCN channel

    HCN_channel

  • Light-gated ion channel

    • Family of transport proteins

    Connexin A GJA1 GJA3 GJA4 GJA5 GJA8 GJA9 GJA10 B GJB1 GJB2 GJB3 GJB4 GJB5 GJB6 GJB7 C GJC1 GJC2 GJC3 D GJD2 GJD3 GJD4 Innexin By gating mechanism Ion channel

    Light-gated ion channel

    Light-gated_ion_channel

  • CNGB1

    • Protein-coding gene in the species Homo sapiens

    Connexin A GJA1 GJA3 GJA4 GJA5 GJA8 GJA9 GJA10 B GJB1 GJB2 GJB3 GJB4 GJB5 GJB6 GJB7 C GJC1 GJC2 GJC3 D GJD2 GJD3 GJD4 Innexin By gating mechanism Ion channel

    CNGB1

    CNGB1

    CNGB1

  • Shaker (gene)

    • Gene found in fruit flies

    Connexin A GJA1 GJA3 GJA4 GJA5 GJA8 GJA9 GJA10 B GJB1 GJB2 GJB3 GJB4 GJB5 GJB6 GJB7 C GJC1 GJC2 GJC3 D GJD2 GJD3 GJD4 Innexin By gating mechanism Ion channel

    Shaker (gene)

    Shaker_(gene)

  • Innexin

    • Transmembrane protein in invertebrates

    Connexin A GJA1 GJA3 GJA4 GJA5 GJA8 GJA9 GJA10 B GJB1 GJB2 GJB3 GJB4 GJB5 GJB6 GJB7 C GJC1 GJC2 GJC3 D GJD2 GJD3 GJD4 Innexin By gating mechanism Ion channel

    Innexin

    Innexin

  • Porin (protein)

    • Group of transport proteins

    Connexin A GJA1 GJA3 GJA4 GJA5 GJA8 GJA9 GJA10 B GJB1 GJB2 GJB3 GJB4 GJB5 GJB6 GJB7 C GJC1 GJC2 GJC3 D GJD2 GJD3 GJD4 Innexin By gating mechanism Ion channel

    Porin (protein)

    Porin (protein)

    Porin_(protein)

  • Sodium voltage-gated channel alpha subunit 9

    • Protein-coding gene in the species Homo sapiens

    Connexin A GJA1 GJA3 GJA4 GJA5 GJA8 GJA9 GJA10 B GJB1 GJB2 GJB3 GJB4 GJB5 GJB6 GJB7 C GJC1 GJC2 GJC3 D GJD2 GJD3 GJD4 Innexin By gating mechanism Ion channel

    Sodium voltage-gated channel alpha subunit 9

    Sodium voltage-gated channel alpha subunit 9

    Sodium_voltage-gated_channel_alpha_subunit_9

  • G protein-coupled inwardly rectifying potassium channel

    • Family of lipid-gated inward-rectifier potassium ion channels

    Connexin A GJA1 GJA3 GJA4 GJA5 GJA8 GJA9 GJA10 B GJB1 GJB2 GJB3 GJB4 GJB5 GJB6 GJB7 C GJC1 GJC2 GJC3 D GJD2 GJD3 GJD4 Innexin By gating mechanism Ion channel

    G protein-coupled inwardly rectifying potassium channel

    G_protein-coupled_inwardly_rectifying_potassium_channel

  • Ryanodine receptor 1

    • Protein and coding gene in humans

    Connexin A GJA1 GJA3 GJA4 GJA5 GJA8 GJA9 GJA10 B GJB1 GJB2 GJB3 GJB4 GJB5 GJB6 GJB7 C GJC1 GJC2 GJC3 D GJD2 GJD3 GJD4 Innexin By gating mechanism Ion channel

    Ryanodine receptor 1

    Ryanodine receptor 1

    Ryanodine_receptor_1

  • ATP-sensitive potassium channel

    • Family of transport proteins

    Connexin A GJA1 GJA3 GJA4 GJA5 GJA8 GJA9 GJA10 B GJB1 GJB2 GJB3 GJB4 GJB5 GJB6 GJB7 C GJC1 GJC2 GJC3 D GJD2 GJD3 GJD4 Innexin By gating mechanism Ion channel

    ATP-sensitive potassium channel

    ATP-sensitive_potassium_channel

  • Kir2.1

    • Protein-coding gene in the species Homo sapiens

    Connexin A GJA1 GJA3 GJA4 GJA5 GJA8 GJA9 GJA10 B GJB1 GJB2 GJB3 GJB4 GJB5 GJB6 GJB7 C GJC1 GJC2 GJC3 D GJD2 GJD3 GJD4 Innexin By gating mechanism Ion channel

    Kir2.1

    Kir2.1

    Kir2.1

  • Two-pore-domain potassium channel

    • Class of transport proteins

    Connexin A GJA1 GJA3 GJA4 GJA5 GJA8 GJA9 GJA10 B GJB1 GJB2 GJB3 GJB4 GJB5 GJB6 GJB7 C GJC1 GJC2 GJC3 D GJD2 GJD3 GJD4 Innexin By gating mechanism Ion channel

    Two-pore-domain potassium channel

    Two-pore-domain potassium channel

    Two-pore-domain_potassium_channel

  • CACNG2

    • Protein found in humans

    Connexin A GJA1 GJA3 GJA4 GJA5 GJA8 GJA9 GJA10 B GJB1 GJB2 GJB3 GJB4 GJB5 GJB6 GJB7 C GJC1 GJC2 GJC3 D GJD2 GJD3 GJD4 Innexin By gating mechanism Ion channel

    CACNG2

    CACNG2

    CACNG2

  • KCNT1

    • Protein-coding gene in the species Homo sapiens

    Connexin A GJA1 GJA3 GJA4 GJA5 GJA8 GJA9 GJA10 B GJB1 GJB2 GJB3 GJB4 GJB5 GJB6 GJB7 C GJC1 GJC2 GJC3 D GJD2 GJD3 GJD4 Innexin By gating mechanism Ion channel

    KCNT1

    KCNT1

    KCNT1

  • GJB2

    • Protein-coding gene in the species Homo sapiens

    Connexin A GJA1 GJA3 GJA4 GJA5 GJA8 GJA9 GJA10 B GJB1 GJB2 GJB3 GJB4 GJB5 GJB6 GJB7 C GJC1 GJC2 GJC3 D GJD2 GJD3 GJD4 Innexin By gating mechanism Ion channel

    GJB2

    GJB2

    GJB2

  • KvLQT2

    • Protein-coding gene in humans

    Connexin A GJA1 GJA3 GJA4 GJA5 GJA8 GJA9 GJA10 B GJB1 GJB2 GJB3 GJB4 GJB5 GJB6 GJB7 C GJC1 GJC2 GJC3 D GJD2 GJD3 GJD4 Innexin By gating mechanism Ion channel

    KvLQT2

    KvLQT2

    KvLQT2

  • CLCN5

    • Mammalian protein found in humans

    Connexin A GJA1 GJA3 GJA4 GJA5 GJA8 GJA9 GJA10 B GJB1 GJB2 GJB3 GJB4 GJB5 GJB6 GJB7 C GJC1 GJC2 GJC3 D GJD2 GJD3 GJD4 Innexin By gating mechanism Ion channel

    CLCN5

    CLCN5

    CLCN5

  • Kir6.2

    • Protein-coding gene in the species Homo sapiens

    Connexin A GJA1 GJA3 GJA4 GJA5 GJA8 GJA9 GJA10 B GJB1 GJB2 GJB3 GJB4 GJB5 GJB6 GJB7 C GJC1 GJC2 GJC3 D GJD2 GJD3 GJD4 Innexin By gating mechanism Ion channel

    Kir6.2

    Kir6.2

    Kir6.2

  • Chloride channel

    • Class of transport proteins

    Connexin A GJA1 GJA3 GJA4 GJA5 GJA8 GJA9 GJA10 B GJB1 GJB2 GJB3 GJB4 GJB5 GJB6 GJB7 C GJC1 GJC2 GJC3 D GJD2 GJD3 GJD4 Innexin By gating mechanism Ion channel

    Chloride channel

    Chloride channel

    Chloride_channel

  • TRPV4

    • Protein-coding gene in humans

    Connexin A GJA1 GJA3 GJA4 GJA5 GJA8 GJA9 GJA10 B GJB1 GJB2 GJB3 GJB4 GJB5 GJB6 GJB7 C GJC1 GJC2 GJC3 D GJD2 GJD3 GJD4 Innexin By gating mechanism Ion channel

    TRPV4

    TRPV4

    TRPV4

  • Kir2.6

    • Mammalian protein found in Homo sapiens

    Connexin A GJA1 GJA3 GJA4 GJA5 GJA8 GJA9 GJA10 B GJB1 GJB2 GJB3 GJB4 GJB5 GJB6 GJB7 C GJC1 GJC2 GJC3 D GJD2 GJD3 GJD4 Innexin By gating mechanism Ion channel

    Kir2.6

    Kir2.6

    Kir2.6

  • KCNV2

    • Protein-coding gene in the species Homo sapiens

    Connexin A GJA1 GJA3 GJA4 GJA5 GJA8 GJA9 GJA10 B GJB1 GJB2 GJB3 GJB4 GJB5 GJB6 GJB7 C GJC1 GJC2 GJC3 D GJD2 GJD3 GJD4 Innexin By gating mechanism Ion channel

    KCNV2

    KCNV2

    KCNV2

  • List of OMIM disorder codes

    • agenesis, microtia, and microdontia; 610706; FGF3 Deafness, digenic GJB2/GJB6; 220290; GJB6 Deafness, digenic, GJB2/GJB3; 220290; GJB3 Deafness, sensorineural

    List of OMIM disorder codes

    List_of_OMIM_disorder_codes

  • KCNK5

    • Protein-coding gene in the species Homo sapiens

    Connexin A GJA1 GJA3 GJA4 GJA5 GJA8 GJA9 GJA10 B GJB1 GJB2 GJB3 GJB4 GJB5 GJB6 GJB7 C GJC1 GJC2 GJC3 D GJD2 GJD3 GJD4 Innexin By gating mechanism Ion channel

    KCNK5

    KCNK5

    KCNK5

  • TRPM3

    • Protein-coding gene in the species Homo sapiens

    Connexin A GJA1 GJA3 GJA4 GJA5 GJA8 GJA9 GJA10 B GJB1 GJB2 GJB3 GJB4 GJB5 GJB6 GJB7 C GJC1 GJC2 GJC3 D GJD2 GJD3 GJD4 Innexin By gating mechanism Ion channel

    TRPM3

    TRPM3

    TRPM3

  • SCNN1B

    • Protein-coding gene in the species Homo sapiens

    Connexin A GJA1 GJA3 GJA4 GJA5 GJA8 GJA9 GJA10 B GJB1 GJB2 GJB3 GJB4 GJB5 GJB6 GJB7 C GJC1 GJC2 GJC3 D GJD2 GJD3 GJD4 Innexin By gating mechanism Ion channel

    SCNN1B

    SCNN1B

    SCNN1B

  • Aquaporin-2

    • Protein-coding gene in the species Homo sapiens

    Connexin A GJA1 GJA3 GJA4 GJA5 GJA8 GJA9 GJA10 B GJB1 GJB2 GJB3 GJB4 GJB5 GJB6 GJB7 C GJC1 GJC2 GJC3 D GJD2 GJD3 GJD4 Innexin By gating mechanism Ion channel

    Aquaporin-2

    Aquaporin-2

    Aquaporin-2

  • Cyclic nucleotide-gated channel alpha 3

    • Protein-coding gene in the species Homo sapiens

    Connexin A GJA1 GJA3 GJA4 GJA5 GJA8 GJA9 GJA10 B GJB1 GJB2 GJB3 GJB4 GJB5 GJB6 GJB7 C GJC1 GJC2 GJC3 D GJD2 GJD3 GJD4 Innexin By gating mechanism Ion channel

    Cyclic nucleotide-gated channel alpha 3

    Cyclic nucleotide-gated channel alpha 3

    Cyclic_nucleotide-gated_channel_alpha_3

  • CLIC1

    • Protein-coding gene in the species Homo sapiens

    Connexin A GJA1 GJA3 GJA4 GJA5 GJA8 GJA9 GJA10 B GJB1 GJB2 GJB3 GJB4 GJB5 GJB6 GJB7 C GJC1 GJC2 GJC3 D GJD2 GJD3 GJD4 Innexin By gating mechanism Ion channel

    CLIC1

    CLIC1

    CLIC1

  • Magnesium transporter

    • Protein family

    Connexin A GJA1 GJA3 GJA4 GJA5 GJA8 GJA9 GJA10 B GJB1 GJB2 GJB3 GJB4 GJB5 GJB6 GJB7 C GJC1 GJC2 GJC3 D GJD2 GJD3 GJD4 Innexin By gating mechanism Ion channel

    Magnesium transporter

    Magnesium_transporter

  • KCNK6

    • Protein-coding gene in humans

    Connexin A GJA1 GJA3 GJA4 GJA5 GJA8 GJA9 GJA10 B GJB1 GJB2 GJB3 GJB4 GJB5 GJB6 GJB7 C GJC1 GJC2 GJC3 D GJD2 GJD3 GJD4 Innexin By gating mechanism Ion channel

    KCNK6

    KCNK6

    KCNK6

  • ASIC3

    • Protein found in humans

    Connexin A GJA1 GJA3 GJA4 GJA5 GJA8 GJA9 GJA10 B GJB1 GJB2 GJB3 GJB4 GJB5 GJB6 GJB7 C GJC1 GJC2 GJC3 D GJD2 GJD3 GJD4 Innexin By gating mechanism Ion channel

    ASIC3

    ASIC3

    ASIC3

  • TRPC

    • Family of transient receptor potential cation channels in animals

    Connexin A GJA1 GJA3 GJA4 GJA5 GJA8 GJA9 GJA10 B GJB1 GJB2 GJB3 GJB4 GJB5 GJB6 GJB7 C GJC1 GJC2 GJC3 D GJD2 GJD3 GJD4 Innexin By gating mechanism Ion channel

    TRPC

    TRPC

  • Cav1.1

    • Mammalian protein found in humans

    Connexin A GJA1 GJA3 GJA4 GJA5 GJA8 GJA9 GJA10 B GJB1 GJB2 GJB3 GJB4 GJB5 GJB6 GJB7 C GJC1 GJC2 GJC3 D GJD2 GJD3 GJD4 Innexin By gating mechanism Ion channel

    Cav1.1

    Cav1.1

    Cav1.1

  • ROMK

    • Potassium channel

    Connexin A GJA1 GJA3 GJA4 GJA5 GJA8 GJA9 GJA10 B GJB1 GJB2 GJB3 GJB4 GJB5 GJB6 GJB7 C GJC1 GJC2 GJC3 D GJD2 GJD3 GJD4 Innexin By gating mechanism Ion channel

    ROMK

    ROMK

    ROMK

  • TRPV

    • Subgroup of TRP cation channels named after the vanilloid receptor

    Connexin A GJA1 GJA3 GJA4 GJA5 GJA8 GJA9 GJA10 B GJB1 GJB2 GJB3 GJB4 GJB5 GJB6 GJB7 C GJC1 GJC2 GJC3 D GJD2 GJD3 GJD4 Innexin By gating mechanism Ion channel

    TRPV

    TRPV

    TRPV

  • KCNA5

    • Protein-coding gene in humans

    Connexin A GJA1 GJA3 GJA4 GJA5 GJA8 GJA9 GJA10 B GJB1 GJB2 GJB3 GJB4 GJB5 GJB6 GJB7 C GJC1 GJC2 GJC3 D GJD2 GJD3 GJD4 Innexin By gating mechanism Ion channel

    KCNA5

    KCNA5

    KCNA5

  • Calcium-activated potassium channel

    • Class of transport proteins

    Connexin A GJA1 GJA3 GJA4 GJA5 GJA8 GJA9 GJA10 B GJB1 GJB2 GJB3 GJB4 GJB5 GJB6 GJB7 C GJC1 GJC2 GJC3 D GJD2 GJD3 GJD4 Innexin By gating mechanism Ion channel

    Calcium-activated potassium channel

    Calcium-activated_potassium_channel

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