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Electric current in the heart
The pacemaker current (If, or IKf, also called funny current) is an electric current in the heart that flows through the HCN channel or pacemaker channel
Pacemaker_current
Electrical potential difference in the heart
cells of the heart (e.g., the sinoatrial node), the pacemaker potential (also called the pacemaker current) is the slow, positive increase in voltage across
Pacemaker_potential
Medical device for artificially stimulating heart contractions
A pacemaker, also known as an artificial cardiac pacemaker, is an implanted medical device that generates electrical pulses delivered by electrodes to
Pacemaker
Network of cells that facilitate rhythmic heart contraction
The natural pacemaker is the heart's natural rhythm generator. It employs pacemaker cells that produce electrical impulses, known as cardiac action potentials
Natural_pacemaker
Heart medication
the brand name Procoralan among others, is a medication, which is a pacemaker current (If) inhibitor, used for the symptomatic management of heart-related
Ivabradine
Intermembrane proteins
The current through HCN channels, designated If or Ih, plays a key role in the control of cardiac and neuronal rhythmicity and is called the pacemaker current
HCN_channel
American neuroscientist and professor emeritus
in the early characterization of the hyperpolarization-activated pacemaker current (f) responsible for the spontaneous rhythmic activity of the sinoatrial
Jeffry_Lansman
Group of cells in the wall of the heart
in the upper back wall of the right atrium made up of cells known as pacemaker cells. The sinus node is approximately 15 mm long, 3 mm wide, and 1 mm
Sinoatrial_node
Specialized cells used to improve heart regulation
A biological pacemaker is one or more types of cellular components that, when "implanted or injected into certain regions of the heart," produce specific
Biological_pacemaker
English band
Gerry and the Pacemakers were an English beat group prominent in the 1960s Merseybeat scene. In common with the Beatles, they came from Liverpool, were
Gerry_and_the_Pacemakers
Italian physiologist (born 1948)
and collaborators discovered the so-called "funny" (or "pacemaker") current in cardiac pacemaker cells, a new mechanism involved in the generation of cardiac
Dario_DiFrancesco
Variation in the time intervals between heartbeats
"pacemaker" current. The "Ik decay" hypothesis proposes that pacemaker depolarization results from slow deactivation of the delayed rectifier current,
Heart_rate_variability
Anticholinergic medication used as antidote for nerve agent poisoning
potassium and calcium currents, as well as the slow-inward sodium current that is thought to be responsible for the pacemaker current (If). By hyperpolarizing
Atropine
Interstitial cells found in the gastrointestinal tract
(1 July 1998). "Interstitial cells of Cajal generate a rhythmic pacemaker current". Nature Medicine. 4 (7): 848–851. doi:10.1038/nm0798-848. ISSN 1078-8956
Interstitial_cell_of_Cajal
Effects that change the heart rate
chronotropic effect. Beta blockers such as metoprolol Acetylcholine Digoxin Pacemaker current (i.e. HCN channel) inhibitors (e.g. ivabradine) Alboni, P.; Menozzi
Chronotropic
Pocket-sized DJ system
The Pacemaker is a pocket-size DJ system invented by Jonas Norberg. The device features include a 120 GB hard drive, a signal-to-noise ratio of 103, and
The_Pacemaker
Part of the enteric nervous system
D. (1998-07-01). "Interstitial cells of Cajal generate a rhythmic pacemaker current". Nature Medicine. 4 (7): 848–851. doi:10.1038/nm0798-848. ISSN 1078-8956
Myenteric_plexus
Biological process in the heart
known as pacemaker cells, that have automatic action potential generation capability. In healthy hearts, these cells form the cardiac pacemaker and are
Cardiac_action_potential
Group of medical conditions characterized by irregular heartbeat
Treatments may include medications, medical procedures such as inserting a pacemaker, and surgery. Medications for a fast heart rate may include beta blockers
Arrhythmia
American journalism awards
The National Pacemaker Awards are awards for excellence in American student journalism, given annually since 1927. The awards are generally considered
National_Pacemaker_Awards
Medical condition
the potassium channel that carries the rapid inward rectifier current IKr. This current contributes to the terminal repolarisation phase of the cardiac
Long_QT_syndrome
Pacemaker crosstalk results when the pacemaker-generated electrical event in one heart chamber is sensed by the lead in another chamber, resulting in inappropriate
Pacemaker_crosstalk
American engineer and inventor (1919–2011)
limited its current load to under 0.1 mA and was thus considered useless. Greatbatch sought to introduce this invention into the pacemaker industry, which
Wilson_Greatbatch
increasing the slope of the pacemaker phase, while parasympathetic activation exerts the opposite action. The amount of net inward current required to move the
Diastolic_depolarization
Devices generating electricity from radioisotope decay
equipment that must operate unattended for long periods, such as spacecraft, pacemakers, medical devices, underwater systems, and automated scientific stations
Atomic_battery
Topics referred to by the same term
organization Isiah Kiner-Falefa (born 1995), American baseball player Pacemaker current of the heart, IKf This disambiguation page lists articles associated
IKF
later time. This contrasts with pacemaker potential or current which drives rhythmic modulation of firing rate. Some pacemaker action generate rhythms for
Pacemaker_action_potential
Irish tax-registered medical device company
systems. They also created miniaturized devices like the world's smallest pacemaker and spinal cord stimulator. Medtronic was founded in 1949 in Minneapolis
Medtronic
Failure of the heart to provide sufficient blood flow throughout the body
shortness of breath. Depending on the case, an implanted device such as a pacemaker or implantable cardiac defibrillator may sometimes be recommended. In
Heart_failure
American physician (1934–2023)
for his work and research in the diagnostic cardiac ultrasound, heart pacemakers, exercise stress testing, and heart catheterization. He was the president
Riaz_Haider
Chemical compound
developed in the 1970s and 1980s. It causes bradycardia by inhibiting the pacemaker current by altering the maximal channel conductance and alter the voltage
Alinidine
Independent student newspaper of the Pennsylvania State University
States receiving multiple notable journalism awards including National Pacemaker Awards, top rankings from The Princeton Review, and Sigma Delta Chi Awards
Daily_Collegian
American engineer, inventor, and holistic healthcare promoter (1924–2018)
first external, battery-operated, transistorized, wearable artificial pacemaker in 1957. Bakken was born on January 10, 1924, in Columbia Heights, Minnesota
Earl_Bakken
activity (ECA) is the spontaneous depolarization and repolarization of pacemaker cells known as interstitial cells of Cajal (ICCs) in the smooth muscle
Basal_electrical_rhythm
Medical imaging procedure
of a body. CT scans can be used in patients with metallic implants or pacemakers, for whom magnetic resonance imaging (MRI) is contraindicated. Since its
CT_scan
Irregular beating of the atria of the heart
of the heart allows electrical impulses generated by the heart's own pacemaker (the sinoatrial node) to spread to and stimulate the muscular layer of
Atrial_fibrillation
Organ found in humans and other animals
with a rhythm determined by a group of pacemaker cells in the sinoatrial node. These generate an electric current that causes the heart to contract, traveling
Heart
American comic book writer (1922–2018)
condominium. In September 2012, Lee underwent an operation to insert a pacemaker, which required cancelling planned appearances at conventions. Lee eventually
Stan_Lee
American distance runner (born 1955)
former professional distance runner and current businessman. In 1981, when running as a designated pacemaker or 'rabbit' in the high-profile 1500 meters
Tom_Byers_(runner)
Autoimmune disease resulting in uncontrollable jerking motions
Raymund A.C. (July 2010). "Sydenham's Chorea: A Practical Overview of the Current Literature". Pediatric Neurology. 43 (1): 1–6. doi:10.1016/j.pediatrneurol
Sydenham's_chorea
Student newspaper of the University of Southern California
organizationally. Associated Collegiate Press – Pacemaker Awards Newspaper Pacemaker Winner: 2017, 1991 Online Pacemaker Winner: 2023, 2016 California College Media
Daily_Trojan
Warm-blooded animals with wings and feathers
during contraction. Being myogenic, the heart's pace is maintained by pacemaker cells found in the sinoatrial node, located on the right atrium. The sinoatrial
Bird
Enlargement of the heart muscle
use of a pacemaker has been advocated in a subset of individuals, to cause asynchronous contraction of the left ventricle. Since the pacemaker activates
Hypertrophic_cardiomyopathy
American cardiologist (1911–1999)
and one of the pioneers in the development of the artificial cardiac pacemaker and cardiac defibrillator. Zoll's parents were Hyman and Mollie Zoll.
Paul_Zoll
Purposeful modulation of nervous system activity
"Implantable pacemaker for the heart". In Smyth CN (ed.). Medical electronics. Paris: Iliffe & Sons. Warren J, Nelson J (2000). "Pacemakers and ICD pulse
Neurostimulation
Sudden or unexpected loss of heartbeat
Revise the ACC/AHA/NASPE 2002 Guideline Update for Implantation of Cardiac Pacemakers and Antiarrhythmia Devices): developed in collaboration with the American
Cardiac_arrest
Disease involving heart or blood vessels
a person could have surgery to replace the valve. For arrhythmias, a pacemaker can be put in place to help reduce abnormal heart rhythms and for a heart
Cardiovascular_disease
Association football club in England
musical Carousel and later recorded by Liverpool musicians Gerry and the Pacemakers, is the club's anthem and has been sung by the Anfield crowd since the
Liverpool_F.C.
Protein-coding gene in the species Homo sapiens
Robinson RB (September 2013). "An LQTS6 MiRP1 mutation suppresses pacemaker current and is associated with sinus bradycardia". Journal of Cardiovascular
KCNE2
Physiological reaction or injury caused by electric current
directly to the heart i.e. a pacemaker lead, or a guide wire, conductive catheter etc. connected to a source of current. This is a largely theoretical
Electrical_injury
2019 attempt to beat a 2-hour marathon
May 2019. 41 pacemakers, rotating in and out in groups of 7, assisted Kipchoge throughout the attempt. Due to the presence of the pacemakers, delivery of
Ineos_1:59_Challenge
Country in North America
major Canadian scientific contributions include the artificial cardiac pacemaker, mapping the visual cortex, the development of the electron microscope
Canada
Medical intervention
reprogramming in a clinically relevant disease model. The currently used electronic pacemakers have drawbacks such as equipment malfunction, limited battery
Tbx18_transduction
Rapid quivering of the ventricles of the heart
myocardial cells. These may then act as pacemakers. The ventricles are then being stimulated by more than one pacemaker. Scar and dying tissue is inexcitable
Ventricular_fibrillation
Ethiopian long-distance runner (born 1982)
drinks at 5 separate stations, due to them being used by the designated pacemakers. 2016 - 2017 On 24 April, he placed third at the 2016 London Marathon
Kenenisa_Bekele
Newspaper in Auburn, Alabama
decorated non-weekly print student publication in the history of the National Pacemaker competition. As of February 2021, the Plainsman is primarily an online
The_Auburn_Plainsman
Reduction of blood flow to the heart
(April 2014). "Screening low-risk individuals for coronary artery disease". Current Atherosclerosis Reports. 16 (4) 402. doi:10.1007/s11883-014-0402-8. PMID 24522859
Coronary_artery_disease
Medical condition
is the heart's "pacemaker". The electrical activity of sinus rhythm originates in the sinoatrial node and depolarizes the atria. Current then passes from
Junctional_rhythm
Medical intervention
device to the commercial market in the early 1970s. The Avery Breathing Pacemaker received pre-market approval from the FDA in 1987 for "chronic ventilatory
Diaphragm_pacing
Infectious disease caused by Borrelia bacteria, spread by ticks
sleeping. About a third of people with Lyme carditis need a temporary pacemaker until their heart conduction abnormality resolves, and 21% need to be
Lyme_disease
Applied science and research
needs, resulting in creations such as bridges, engines, smartphones, pacemakers, the internet, spacecraft, and washing machines. Engineering involves
Engineering
Medical condition
is a family history of PCCD. At the moment, implanting an implantable pacemaker is the only proven treatment for PCCD, regardless of the underlying cause
Progressive cardiac conduction defect
Progressive_cardiac_conduction_defect
Complications resulting from surgical incision of the pericardium
placement after a myocardial infarction or heart attack), or due to pacemaker or pacemaker wire placement. The typical signs of post-pericardiotomy syndrome
Postpericardiotomy_syndrome
man with severe chest pains who needs urgent medical attention and a pacemaker, but the patient states his desire is to die. Ultimately, Jared chooses
List of The Good Doctor episodes
List_of_The_Good_Doctor_episodes
Teddy Boy The Back Seat of My Car Jimmy McCracklin The Walk Gerry and the Pacemakers Don't Let the Sun Catch You Crying Carl Perkins Blue Suede Shoes Gone
The Beatles' recording sessions
The_Beatles'_recording_sessions
Examination of the heart's electrical activity
healthy heart has an orderly progression of depolarization that starts with pacemaker cells in the sinoatrial node, spreads throughout the atrium, and passes
Electrocardiography
Autoimmune disease
heart beat, sometimes to the point that the heart beat stops and requires pacemaker-based treatment. Other associated problems are abnormalities in perspiration
Guillain–Barré_syndrome
Drug mixture used mainly to treat ADHD and narcolepsy
interval timing, leading to the hypothesis that dopamine influences internal pacemaker, or "clock," activity. For instance, amphetamine, which increases concentrations
Adderall
Volcanic supereruption 74,000 years ago in Indonesia
John; Shackleton, N. J. (1976-12-10). "Variations in the Earth's Orbit: Pacemaker of the Ice Ages: For 500,000 years, major climatic changes have followed
Youngest_Toba_eruption
Chinese long-distance runner
appeared to let him win. Mnangat later said that he was entered as a pacemaker for He, not unusual in road races, and that he was never intended to be
He_Jie_(runner)
Public university in Auburn, Alabama, US
paper is the most decorated student publication, receiving more National Pacemaker Awards, handed out by the Associated Collegiate Press, than any other
Auburn_University
Public school in St. Louis Park, Minnesota, United States
newspaper, Echo was named a Newspaper Pacemaker finalist in 2019. Echo had previously received the Newspaper Pacemaker in 2018, 2017, 2015, 2014, 2013 and
St._Louis_Park_High_School
Central nervous system stimulant
interval timing, leading to the hypothesis that dopamine influences internal pacemaker, or "clock," activity. For instance, amphetamine, which increases concentrations
Amphetamine
Texas Tech University student newspaper
Association Silver crown awards, and two Associated Collegiate Press Pacemaker Award finalists. As well, the paper counts five Pulitzer Prizes and four
The_Daily_Toreador
Naturally recurring resting state of mind and body
not) and drops to almost nothing during subjective night. The circadian pacemaker in the suprachiasmatic nucleus has a direct neural connection to the pineal
Sleep
Jonī Sasaki Sureitā) and was a spy for the Patriots who would die from a pacemaker malfunction after coming into contact with Raiden. During the game, Raiden
Characters of the Metal Gear series
Characters_of_the_Metal_Gear_series
CNS stimulant and isomer of amphetamine
interval timing, leading to the hypothesis that dopamine influences internal pacemaker, or "clock," activity. For instance, amphetamine, which increases concentrations
Dextroamphetamine
American sportscaster (1924–2002)
suffered from such ailments as Parkinson's disease, diabetes, requiring a pacemaker, cataracts, sciatica, and vertigo. Buck once joked, "I wish I'd get Alzheimer's
Jack_Buck
English broadcaster and natural historian (born 1926)
independent schools like the Emmanuel Schools Foundation. Attenborough had a pacemaker fitted in June 2013, as well as a double knee replacement in 2015. In
David_Attenborough
American comedian and actress (1917–2012)
1999, her heart stopped during a hospital stay. She was fitted with a pacemaker but had a bad drug reaction and became paralyzed. Through physical therapy
Phyllis_Diller
City in Merseyside, England
originated in the city including Billy J. Kramer, Cilla Black, Gerry and the Pacemakers and the Searchers. The influence of musicians from Liverpool, coupled
Liverpool
Indian-American chronobiologist
RDL's role in PDF pacemaker neuron inhibition was supported by electrophysiological evidence that GABA induced an inward current of chloride and GABA
Ravi_Allada
Medical device
implantation of an ICD system is similar to implantation of an artificial pacemaker. The first component or generator contains a computer chip or circuitry
Implantable cardioverter-defibrillator
Implantable_cardioverter-defibrillator
Energy collected from renewable resources
microelectromechanical systems (piezoMEMS), such as actuators for artificial organs and pacemakers or micropumps for drug delivery and reagent transfers, are vital for medical
Renewable_energy
Sexual practice
cardiac arrest), and this risk is higher for those who use an artificial pacemaker or similar device or who have heart conditions. A few cases of accidental
Erotic_electrostimulation
Desert on the African continent
Dār al-'Ilm lil-Malāyīn. p. 689. Chu, Jennifer (2 January 2019). "A "pacemaker" for North African climate". MIT News. Archived from the original on 15
Sahara
Australian rock band
cancerous tissue removed. He also had an unspecified heart problem and had a pacemaker fitted. Malcolm became seriously ill in April 2014 and was unable to continue
AC/DC
Blood clot within the heart's blood vessels
myocardial infarction over a 15-year period. There are numerous treatments currently being studied for management and prevention of coronary thrombosis. Statin
Coronary_thrombosis
Treatment for life-threatening cardiac arrhythmias
heart muscle, ending the arrhythmia. Subsequently, the body's natural pacemaker in the sinoatrial node of the heart is able to re-establish normal sinus
Defibrillation
American politician (born 1969)
rhythm). Because Fetterman also had cardiomyopathy, his doctors implanted a pacemaker and defibrillator. He was discharged from the hospital on May 22, 2022
John_Fetterman
Inflammation of the heart muscle
(October 2022). "Biomarkers for Myocarditis and Inflammatory Cardiomyopathy". Current Heart Failure Reports. 19 (5): 346–355. doi:10.1007/s11897-022-00569-8
Myocarditis
Class of animals
muscles. The main structures of the heart are the sinus venosus, the pacemaker, the left atrium, the right atrium, the atrioventricular valve, the cavum
Reptile
C.H. (Positive Approach to Changing Humans) c-16m July 23, 1970 Video Pacemakers and Your Heart Rhythm c-13m 1982 Cardiology: You & Your Heart The Pacific
List_of_Coronet_Films_films
Medical condition
after a heart attack, and reduce the risk of death in some patients. A pacemaker is a small device that's placed in the chest or abdomen to help control
Acute decompensated heart failure
Acute_decompensated_heart_failure
Sudden temporary weakening of the heart muscle
Retrieved 27 May 2017. McPhee SJ, Rabow MW, Papadakis MA (1 September 2016). Current medical diagnosis & treatment 2017 (Fifty-sixth ed.). New York: McGraw
Takotsubo_cardiomyopathy
American physician and inventor (1936–2022)
Greatbach, one early developer of the implantable pacemaker, to develop an MRI-compatible pacemaker. The Franklin Institute in Philadelphia gave its recognition
Raymond_Damadian
Belgian footballer (born 1997)
12 May 2025. Fisher, Ben (20 January 2025). "Youri Tielemans now the pacemaker at heart of Aston Villa's resurgence". The Guardian. ISSN 0261-3077. Retrieved
Youri_Tielemans
Specific aspects of Benjamin Banneker's life and legacy
all men. Banks, Dr. Melvin (October 17, 2013). "Benjamin Banneker Was A Pacemaker". Urban Faith. Archived from the original on October 21, 2013. Retrieved
Mythology of Benjamin Banneker
Mythology_of_Benjamin_Banneker
Public secondary school in Reno, Nevada, United States
student publication in the state to be inducted. It won a NSPA Newspaper Pacemaker in 2009. "McQueen TV" — closed circuit television station (daily broadcast
Robert_McQueen_High_School
Use of knowledge for practical goals
and MRI scanning), treatment (like the dialysis machine, defibrillator, pacemaker, and a wide array of new pharmaceutical drugs), and research (like interferon
Technology
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