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VANDETANIB

  • Vandetanib

    • Chemical compound

    Vandetanib, sold under the brand name Caprelsa, is an anti-cancer medication that is used for the treatment of certain tumors of the thyroid gland. It

    Vandetanib

    Vandetanib

    Vandetanib

  • Pascal Soriot

    • French businessman

    cyclosilicate Tamoxifen Ticagrelor Tixagevimab/cilgavimab Trastuzumab deruxtecan Vandetanib Vaxzevria Ximelagatran Zafirlukast Zolmitriptan Predecessors and acquired

    Pascal Soriot

    Pascal Soriot

    Pascal_Soriot

  • Rosuvastatin

    • Statin medication

    cyclosilicate Tamoxifen Ticagrelor Tixagevimab/cilgavimab Trastuzumab deruxtecan Vandetanib Vaxzevria Ximelagatran Zafirlukast Zolmitriptan Predecessors and acquired

    Rosuvastatin

    Rosuvastatin

    Rosuvastatin

  • Bevacizumab

    • Medication

    inhibitors: Vandetanib GFRα2 Agonists: Neurturin (NRTN) Kinase inhibitors: Vandetanib GFRα3 Agonists: Artemin (ARTN) Kinase inhibitors: Vandetanib GFRα4 Agonists:

    Bevacizumab

    Bevacizumab

  • Omeprazole

    • Medication to treat gastroesophageal reflux disease and other conditions

    cyclosilicate Tamoxifen Ticagrelor Tixagevimab/cilgavimab Trastuzumab deruxtecan Vandetanib Vaxzevria Ximelagatran Zafirlukast Zolmitriptan Predecessors and acquired

    Omeprazole

    Omeprazole

  • Selpercatinib

    • Chemical compound

    require systemic therapy following prior treatment with cabozantinib and/or vandetanib. In September 2024, the FDA granted traditional approval to selpercatinib

    Selpercatinib

    Selpercatinib

    Selpercatinib

  • Imatinib

    • Chemical compound

    inhibitors: Vandetanib GFRα2 Agonists: Neurturin (NRTN) Kinase inhibitors: Vandetanib GFRα3 Agonists: Artemin (ARTN) Kinase inhibitors: Vandetanib GFRα4 Agonists:

    Imatinib

    Imatinib

    Imatinib

  • Erythropoietin

    • Protein that stimulates red blood cell production

    inhibitors: Vandetanib GFRα2 Agonists: Neurturin (NRTN) Kinase inhibitors: Vandetanib GFRα3 Agonists: Artemin (ARTN) Kinase inhibitors: Vandetanib GFRα4 Agonists:

    Erythropoietin

    Erythropoietin

    Erythropoietin

  • Trastuzumab

    • Medication

    inhibitors: Vandetanib GFRα2 Agonists: Neurturin (NRTN) Kinase inhibitors: Vandetanib GFRα3 Agonists: Artemin (ARTN) Kinase inhibitors: Vandetanib GFRα4 Agonists:

    Trastuzumab

    Trastuzumab

    Trastuzumab

  • Cabozantinib

    • Chemical compound

    inhibitors: Vandetanib GFRα2 Agonists: Neurturin (NRTN) Kinase inhibitors: Vandetanib GFRα3 Agonists: Artemin (ARTN) Kinase inhibitors: Vandetanib GFRα4 Agonists:

    Cabozantinib

    Cabozantinib

    Cabozantinib

  • Wnt signaling pathway

    • Group of signal transduction pathways involved in embryonic development

    inhibitors: Vandetanib GFRα2 Agonists: Neurturin (NRTN) Kinase inhibitors: Vandetanib GFRα3 Agonists: Artemin (ARTN) Kinase inhibitors: Vandetanib GFRα4 Agonists:

    Wnt signaling pathway

    Wnt_signaling_pathway

  • Propofol

    • Intravenous medication used in anesthesia

    cyclosilicate Tamoxifen Ticagrelor Tixagevimab/cilgavimab Trastuzumab deruxtecan Vandetanib Vaxzevria Ximelagatran Zafirlukast Zolmitriptan Predecessors and acquired

    Propofol

    Propofol

    Propofol

  • Biological half-life

    • Time taken for a drug to halve its concentration in blood plasma

    Österreichischer Apothekerverlag. Sedacoron 200 mg-Tabletten. "Caprelsa (vandetanib) Tablets, for Oral Use. Full Prescribing Information" (PDF). Sanofi Genzyme

    Biological half-life

    Biological half-life

    Biological_half-life

  • Fosgonimeton

    • Chemical compound

    inhibitors: Vandetanib GFRα2 Agonists: Neurturin (NRTN) Kinase inhibitors: Vandetanib GFRα3 Agonists: Artemin (ARTN) Kinase inhibitors: Vandetanib GFRα4 Agonists:

    Fosgonimeton

    Fosgonimeton

    Fosgonimeton

  • Insulin-like growth factor

    • Proteins similar to insulin that stimulate cell proliferation

    inhibitors: Vandetanib GFRα2 Agonists: Neurturin (NRTN) Kinase inhibitors: Vandetanib GFRα3 Agonists: Artemin (ARTN) Kinase inhibitors: Vandetanib GFRα4 Agonists:

    Insulin-like growth factor

    Insulin-like growth factor

    Insulin-like_growth_factor

  • Vemurafenib

    • Targeted cancer drug

    inhibitors: Vandetanib GFRα2 Agonists: Neurturin (NRTN) Kinase inhibitors: Vandetanib GFRα3 Agonists: Artemin (ARTN) Kinase inhibitors: Vandetanib GFRα4 Agonists:

    Vemurafenib

    Vemurafenib

    Vemurafenib

  • AstraZeneca

    • Swedish-British pharmaceutical company

    July, Genzyme announced it would acquire the rare cancer drug Caprelsa (vandetanib) from AstraZeneca for up to US$300 million. In August, the company announced

    AstraZeneca

    AstraZeneca

    AstraZeneca

  • Dexamethasone

    • Corticosteroid medication

    inhibitors: Vandetanib GFRα2 Agonists: Neurturin (NRTN) Kinase inhibitors: Vandetanib GFRα3 Agonists: Artemin (ARTN) Kinase inhibitors: Vandetanib GFRα4 Agonists:

    Dexamethasone

    Dexamethasone

    Dexamethasone

  • Alectinib

    • ALK inhibitor for treatment of non-small-cell lung cancer

    inhibitors: Vandetanib GFRα2 Agonists: Neurturin (NRTN) Kinase inhibitors: Vandetanib GFRα3 Agonists: Artemin (ARTN) Kinase inhibitors: Vandetanib GFRα4 Agonists:

    Alectinib

    Alectinib

    Alectinib

  • Hantaviridae

    • Family of viruses

    improve survival rates, including lactoferrin, ribavirin, favipiravir and vandetanib. Human infection with hantaviruses typically arises from exposure to virus-contaminated

    Hantaviridae

    Hantaviridae

    Hantaviridae

  • GDNF family of ligands

    • Erlotinib Gefitinib Grandinin Icotinib Lapatinib Neratinib Osimertinib Vandetanib WHI-P 154 Antibodies: Cetuximab Depatuxizumab Depatuxizumab mafodotin

    GDNF family of ligands

    GDNF family of ligands

    GDNF_family_of_ligands

  • Amivantamab

    • Monoclonal antibody

    inhibitors: Vandetanib GFRα2 Agonists: Neurturin (NRTN) Kinase inhibitors: Vandetanib GFRα3 Agonists: Artemin (ARTN) Kinase inhibitors: Vandetanib GFRα4 Agonists:

    Amivantamab

    Amivantamab

    Amivantamab

  • Anti-VEGF

    • Medication which blocks growth of blood vessels

    lenvatinib cancer pazopanib cancer ponatinib cancer ramucirumab cancer ranibizumab AMD regorafenib cancer sorafenib cancer sunitinib cancer vandetanib cancer

    Anti-VEGF

    Anti-VEGF

    Anti-VEGF

  • Tyrosine kinase inhibitor

    • Drug typically used in cancer treatment

    Erlotinib Gefitinib Grandinin Icotinib Lapatinib Neratinib Osimertinib Vandetanib WHI-P 154 Antibodies: Cetuximab Depatuxizumab Depatuxizumab mafodotin

    Tyrosine kinase inhibitor

    Tyrosine kinase inhibitor

    Tyrosine_kinase_inhibitor

  • Encorafenib

    • Chemical compound

    inhibitors: Vandetanib GFRα2 Agonists: Neurturin (NRTN) Kinase inhibitors: Vandetanib GFRα3 Agonists: Artemin (ARTN) Kinase inhibitors: Vandetanib GFRα4 Agonists:

    Encorafenib

    Encorafenib

    Encorafenib

  • Integrin

    • Transmembrane receptors involved in cellular adhesion and signalling

    inhibitors: Vandetanib GFRα2 Agonists: Neurturin (NRTN) Kinase inhibitors: Vandetanib GFRα3 Agonists: Artemin (ARTN) Kinase inhibitors: Vandetanib GFRα4 Agonists:

    Integrin

    Integrin

    Integrin

  • Elranatamab

    • Medication

    Mobocertinib Olmutinib Osimertinib Rociletinib Sevabertinib Sunvozertinib Vandetanib) HER1/EGFR and HER2/neu Lapatinib Neratinib Tucatinib Zongertinib BRAF

    Elranatamab

    Elranatamab

  • Neurotrophic factors

    • Family of biomolecules

    inhibitors: Vandetanib GFRα2 Agonists: Neurturin (NRTN) Kinase inhibitors: Vandetanib GFRα3 Agonists: Artemin (ARTN) Kinase inhibitors: Vandetanib GFRα4 Agonists:

    Neurotrophic factors

    Neurotrophic_factors

  • Mecasermin

    • Pharmaceutical drug

    Erlotinib Gefitinib Grandinin Icotinib Lapatinib Neratinib Osimertinib Vandetanib WHI-P 154 Antibodies: Cetuximab Depatuxizumab Depatuxizumab mafodotin

    Mecasermin

    Mecasermin

  • IGF-1 LR3

    • Synthetic protein

    Erlotinib Gefitinib Grandinin Icotinib Lapatinib Neratinib Osimertinib Vandetanib WHI-P 154 Antibodies: Cetuximab Depatuxizumab Depatuxizumab mafodotin

    IGF-1 LR3

    IGF-1_LR3

  • Crizotinib

    • ALK inhibitor for treatment of non-small-cell lung cancer

    inhibitors: Vandetanib GFRα2 Agonists: Neurturin (NRTN) Kinase inhibitors: Vandetanib GFRα3 Agonists: Artemin (ARTN) Kinase inhibitors: Vandetanib GFRα4 Agonists:

    Crizotinib

    Crizotinib

    Crizotinib

  • VEGF receptor

    • Protein family

    inhibitors: Vandetanib GFRα2 Agonists: Neurturin (NRTN) Kinase inhibitors: Vandetanib GFRα3 Agonists: Artemin (ARTN) Kinase inhibitors: Vandetanib GFRα4 Agonists:

    VEGF receptor

    VEGF receptor

    VEGF_receptor

  • Dihexa

    • Chemical compound

    inhibitors: Vandetanib GFRα2 Agonists: Neurturin (NRTN) Kinase inhibitors: Vandetanib GFRα3 Agonists: Artemin (ARTN) Kinase inhibitors: Vandetanib GFRα4 Agonists:

    Dihexa

    Dihexa

    Dihexa

  • Axitinib

    • Chemical compound

    inhibitors: Vandetanib GFRα2 Agonists: Neurturin (NRTN) Kinase inhibitors: Vandetanib GFRα3 Agonists: Artemin (ARTN) Kinase inhibitors: Vandetanib GFRα4 Agonists:

    Axitinib

    Axitinib

    Axitinib

  • Insulin-like growth factor 1

    • Protein found in humans

    inhibitors: Vandetanib GFRα2 Agonists: Neurturin (NRTN) Kinase inhibitors: Vandetanib GFRα3 Agonists: Artemin (ARTN) Kinase inhibitors: Vandetanib GFRα4 Agonists:

    Insulin-like growth factor 1

    Insulin-like growth factor 1

    Insulin-like_growth_factor_1

  • Astra AB

    • Swedish multinational pharmaceutical company

    cyclosilicate Tamoxifen Ticagrelor Tixagevimab/cilgavimab Trastuzumab deruxtecan Vandetanib Vaxzevria Ximelagatran Zafirlukast Zolmitriptan Predecessors and acquired

    Astra AB

    Astra AB

    Astra_AB

  • Osimertinib

    • Chemical compound, used as a medication to treat lung cancer

    inhibitors: Vandetanib GFRα2 Agonists: Neurturin (NRTN) Kinase inhibitors: Vandetanib GFRα3 Agonists: Artemin (ARTN) Kinase inhibitors: Vandetanib GFRα4 Agonists:

    Osimertinib

    Osimertinib

    Osimertinib

  • Growth factor

    • Protein or other substance that stimulates cellular proliferation

    inhibitors: Vandetanib GFRα2 Agonists: Neurturin (NRTN) Kinase inhibitors: Vandetanib GFRα3 Agonists: Artemin (ARTN) Kinase inhibitors: Vandetanib GFRα4 Agonists:

    Growth factor

    Growth_factor

  • Trastuzumab emtansine

    • Pharmaceutical drug

    inhibitors: Vandetanib GFRα2 Agonists: Neurturin (NRTN) Kinase inhibitors: Vandetanib GFRα3 Agonists: Artemin (ARTN) Kinase inhibitors: Vandetanib GFRα4 Agonists:

    Trastuzumab emtansine

    Trastuzumab emtansine

    Trastuzumab_emtansine

  • Neratinib

    • Chemical compound

    inhibitors: Vandetanib GFRα2 Agonists: Neurturin (NRTN) Kinase inhibitors: Vandetanib GFRα3 Agonists: Artemin (ARTN) Kinase inhibitors: Vandetanib GFRα4 Agonists:

    Neratinib

    Neratinib

    Neratinib

  • Receptor tyrosine kinase

    • Class of enzymes

    inhibitors: Vandetanib GFRα2 Agonists: Neurturin (NRTN) Kinase inhibitors: Vandetanib GFRα3 Agonists: Artemin (ARTN) Kinase inhibitors: Vandetanib GFRα4 Agonists:

    Receptor tyrosine kinase

    Receptor tyrosine kinase

    Receptor_tyrosine_kinase

  • Asciminib

    • Chemical compound

    inhibitors: Vandetanib GFRα2 Agonists: Neurturin (NRTN) Kinase inhibitors: Vandetanib GFRα3 Agonists: Artemin (ARTN) Kinase inhibitors: Vandetanib GFRα4 Agonists:

    Asciminib

    Asciminib

    Asciminib

  • Nilotinib

    • Chemical compound

    inhibitors: Vandetanib GFRα2 Agonists: Neurturin (NRTN) Kinase inhibitors: Vandetanib GFRα3 Agonists: Artemin (ARTN) Kinase inhibitors: Vandetanib GFRα4 Agonists:

    Nilotinib

    Nilotinib

    Nilotinib

  • Tropoflavin

    • Chemical compound

    inhibitors: Vandetanib GFRα2 Agonists: Neurturin (NRTN) Kinase inhibitors: Vandetanib GFRα3 Agonists: Artemin (ARTN) Kinase inhibitors: Vandetanib GFRα4 Agonists:

    Tropoflavin

    Tropoflavin

    Tropoflavin

  • Pazopanib

    • Chemical compound

    inhibitors: Vandetanib GFRα2 Agonists: Neurturin (NRTN) Kinase inhibitors: Vandetanib GFRα3 Agonists: Artemin (ARTN) Kinase inhibitors: Vandetanib GFRα4 Agonists:

    Pazopanib

    Pazopanib

  • Insulin

    • Peptide hormone

    inhibitors: Vandetanib GFRα2 Agonists: Neurturin (NRTN) Kinase inhibitors: Vandetanib GFRα3 Agonists: Artemin (ARTN) Kinase inhibitors: Vandetanib GFRα4 Agonists:

    Insulin

    Insulin

    Insulin

  • Brigatinib

    • ALK inhibitor for treatment of non-small-cell lung cancer

    inhibitors: Vandetanib GFRα2 Agonists: Neurturin (NRTN) Kinase inhibitors: Vandetanib GFRα3 Agonists: Artemin (ARTN) Kinase inhibitors: Vandetanib GFRα4 Agonists:

    Brigatinib

    Brigatinib

    Brigatinib

  • Pertuzumab

    • Pharmaceutical drug

    Erlotinib Gefitinib Grandinin Icotinib Lapatinib Neratinib Osimertinib Vandetanib WHI-P 154 Antibodies: Cetuximab Depatuxizumab Depatuxizumab mafodotin

    Pertuzumab

    Pertuzumab

    Pertuzumab

  • Hepatocyte growth factor

    • Mammalian protein found in Homo sapiens

    inhibitors: Vandetanib GFRα2 Agonists: Neurturin (NRTN) Kinase inhibitors: Vandetanib GFRα3 Agonists: Artemin (ARTN) Kinase inhibitors: Vandetanib GFRα4 Agonists:

    Hepatocyte growth factor

    Hepatocyte_growth_factor

  • Dapagliflozin

    • Diabetes medication

    cyclosilicate Tamoxifen Ticagrelor Tixagevimab/cilgavimab Trastuzumab deruxtecan Vandetanib Vaxzevria Ximelagatran Zafirlukast Zolmitriptan Predecessors and acquired

    Dapagliflozin

    Dapagliflozin

    Dapagliflozin

  • E2511

    • Pharmaceutical compound

    Erlotinib Gefitinib Grandinin Icotinib Lapatinib Neratinib Osimertinib Vandetanib WHI-P 154 Antibodies: Cetuximab Depatuxizumab Depatuxizumab mafodotin

    E2511

    E2511

  • Brain-derived neurotrophic factor

    • Protein found in humans

    inhibitors: Vandetanib GFRα2 Agonists: Neurturin (NRTN) Kinase inhibitors: Vandetanib GFRα3 Agonists: Artemin (ARTN) Kinase inhibitors: Vandetanib GFRα4 Agonists:

    Brain-derived neurotrophic factor

    Brain-derived neurotrophic factor

    Brain-derived_neurotrophic_factor

  • Infigratinib

    • Medication

    inhibitors: Vandetanib GFRα2 Agonists: Neurturin (NRTN) Kinase inhibitors: Vandetanib GFRα3 Agonists: Artemin (ARTN) Kinase inhibitors: Vandetanib GFRα4 Agonists:

    Infigratinib

    Infigratinib

  • Tanezumab

    • Chemical compound

    inhibitors: Vandetanib GFRα2 Agonists: Neurturin (NRTN) Kinase inhibitors: Vandetanib GFRα3 Agonists: Artemin (ARTN) Kinase inhibitors: Vandetanib GFRα4 Agonists:

    Tanezumab

    Tanezumab

  • Lorlatinib

    • Kinase inhibitor for treatment of non-small-cell lung cancer

    inhibitors: Vandetanib GFRα2 Agonists: Neurturin (NRTN) Kinase inhibitors: Vandetanib GFRα3 Agonists: Artemin (ARTN) Kinase inhibitors: Vandetanib GFRα4 Agonists:

    Lorlatinib

    Lorlatinib

    Lorlatinib

  • Epidermal growth factor

    • Protein that stimulates cell division and differentiation

    inhibitors: Vandetanib GFRα2 Agonists: Neurturin (NRTN) Kinase inhibitors: Vandetanib GFRα3 Agonists: Artemin (ARTN) Kinase inhibitors: Vandetanib GFRα4 Agonists:

    Epidermal growth factor

    Epidermal growth factor

    Epidermal_growth_factor

  • Nerve growth factor

    • Mammalian protein found in humans

    inhibitors: Vandetanib GFRα2 Agonists: Neurturin (NRTN) Kinase inhibitors: Vandetanib GFRα3 Agonists: Artemin (ARTN) Kinase inhibitors: Vandetanib GFRα4 Agonists:

    Nerve growth factor

    Nerve growth factor

    Nerve_growth_factor

  • Nirsevimab

    • Monoclonal antibody used as vaccine against RSV

    cyclosilicate Tamoxifen Ticagrelor Tixagevimab/cilgavimab Trastuzumab deruxtecan Vandetanib Vaxzevria Ximelagatran Zafirlukast Zolmitriptan Predecessors and acquired

    Nirsevimab

    Nirsevimab

  • Tucatinib

    • Chemical compound

    inhibitors: Vandetanib GFRα2 Agonists: Neurturin (NRTN) Kinase inhibitors: Vandetanib GFRα3 Agonists: Artemin (ARTN) Kinase inhibitors: Vandetanib GFRα4 Agonists:

    Tucatinib

    Tucatinib

    Tucatinib

  • Avapritinib

    • Chemical compound

    inhibitors: Vandetanib GFRα2 Agonists: Neurturin (NRTN) Kinase inhibitors: Vandetanib GFRα3 Agonists: Artemin (ARTN) Kinase inhibitors: Vandetanib GFRα4 Agonists:

    Avapritinib

    Avapritinib

    Avapritinib

  • Candesartan

    • Angiotensin II receptor antagonist

    cyclosilicate Tamoxifen Ticagrelor Tixagevimab/cilgavimab Trastuzumab deruxtecan Vandetanib Vaxzevria Ximelagatran Zafirlukast Zolmitriptan Predecessors and acquired

    Candesartan

    Candesartan

    Candesartan

  • Panitumumab

    • Pharmaceutical drug

    inhibitors: Vandetanib GFRα2 Agonists: Neurturin (NRTN) Kinase inhibitors: Vandetanib GFRα3 Agonists: Artemin (ARTN) Kinase inhibitors: Vandetanib GFRα4 Agonists:

    Panitumumab

    Panitumumab

  • Filgrastim

    • Medication

    inhibitors: Vandetanib GFRα2 Agonists: Neurturin (NRTN) Kinase inhibitors: Vandetanib GFRα3 Agonists: Artemin (ARTN) Kinase inhibitors: Vandetanib GFRα4 Agonists:

    Filgrastim

    Filgrastim

    Filgrastim

  • Cerebrolysin

    • Experimental drug for neurodegenerative disorders

    Erlotinib Gefitinib Grandinin Icotinib Lapatinib Neratinib Osimertinib Vandetanib WHI-P 154 Antibodies: Cetuximab Depatuxizumab Depatuxizumab mafodotin

    Cerebrolysin

    Cerebrolysin

  • Vascular endothelial growth factor

    • Protein involved in blood vessel growth

    inhibitors: Vandetanib GFRα2 Agonists: Neurturin (NRTN) Kinase inhibitors: Vandetanib GFRα3 Agonists: Artemin (ARTN) Kinase inhibitors: Vandetanib GFRα4 Agonists:

    Vascular endothelial growth factor

    Vascular_endothelial_growth_factor

  • Dirty drug

    • Informal term for a drug that binds to many different molecular targets or receptors

    Examples of "promiscuous" cancer drugs include: sunitinib, sorafenib, vandetanib, and axitinib.[citation needed] In the field of drugs used to treat depression

    Dirty drug

    Dirty_drug

  • Ranibizumab

    • Pharmaceutical drug

    inhibitors: Vandetanib GFRα2 Agonists: Neurturin (NRTN) Kinase inhibitors: Vandetanib GFRα3 Agonists: Artemin (ARTN) Kinase inhibitors: Vandetanib GFRα4 Agonists:

    Ranibizumab

    Ranibizumab

  • Angiopoietin

    • Protein family

    inhibitors: Vandetanib GFRα2 Agonists: Neurturin (NRTN) Kinase inhibitors: Vandetanib GFRα3 Agonists: Artemin (ARTN) Kinase inhibitors: Vandetanib GFRα4 Agonists:

    Angiopoietin

    Angiopoietin

    Angiopoietin

  • Fibroblast growth factor receptor

    • Family of proteins that bind to fibroblast growth factors

    inhibitors: Vandetanib GFRα2 Agonists: Neurturin (NRTN) Kinase inhibitors: Vandetanib GFRα3 Agonists: Artemin (ARTN) Kinase inhibitors: Vandetanib GFRα4 Agonists:

    Fibroblast growth factor receptor

    Fibroblast_growth_factor_receptor

  • Fibroblast growth factor receptor 3

    • Gene involved in the most common form of dwarfism

    inhibitors: Vandetanib GFRα2 Agonists: Neurturin (NRTN) Kinase inhibitors: Vandetanib GFRα3 Agonists: Artemin (ARTN) Kinase inhibitors: Vandetanib GFRα4 Agonists:

    Fibroblast growth factor receptor 3

    Fibroblast growth factor receptor 3

    Fibroblast_growth_factor_receptor_3

  • Platelet-derived growth factor receptor

    • Cell surface receptors

    inhibitors: Vandetanib GFRα2 Agonists: Neurturin (NRTN) Kinase inhibitors: Vandetanib GFRα3 Agonists: Artemin (ARTN) Kinase inhibitors: Vandetanib GFRα4 Agonists:

    Platelet-derived growth factor receptor

    Platelet-derived growth factor receptor

    Platelet-derived_growth_factor_receptor

  • Binimetinib

    • Chemical compound

    inhibitors: Vandetanib GFRα2 Agonists: Neurturin (NRTN) Kinase inhibitors: Vandetanib GFRα3 Agonists: Artemin (ARTN) Kinase inhibitors: Vandetanib GFRα4 Agonists:

    Binimetinib

    Binimetinib

    Binimetinib

  • Masitinib

    • Chemical compound

    inhibitors: Vandetanib GFRα2 Agonists: Neurturin (NRTN) Kinase inhibitors: Vandetanib GFRα3 Agonists: Artemin (ARTN) Kinase inhibitors: Vandetanib GFRα4 Agonists:

    Masitinib

    Masitinib

    Masitinib

  • Amivantamab/hyaluronidase

    • Medication

    Erlotinib Gefitinib Grandinin Icotinib Lapatinib Neratinib Osimertinib Vandetanib WHI-P 154 Antibodies: Cetuximab Depatuxizumab Depatuxizumab mafodotin

    Amivantamab/hyaluronidase

    Amivantamab/hyaluronidase

  • Figitumumab

    • Chemical compound

    Erlotinib Gefitinib Grandinin Icotinib Lapatinib Neratinib Osimertinib Vandetanib WHI-P 154 Antibodies: Cetuximab Depatuxizumab Depatuxizumab mafodotin

    Figitumumab

    Figitumumab

  • Fibroblast growth factor 23

    • Protein found in humans

    inhibitors: Vandetanib GFRα2 Agonists: Neurturin (NRTN) Kinase inhibitors: Vandetanib GFRα3 Agonists: Artemin (ARTN) Kinase inhibitors: Vandetanib GFRα4 Agonists:

    Fibroblast growth factor 23

    Fibroblast growth factor 23

    Fibroblast_growth_factor_23

  • CCN family member 2

    • Protein found in humans

    inhibitors: Vandetanib GFRα2 Agonists: Neurturin (NRTN) Kinase inhibitors: Vandetanib GFRα3 Agonists: Artemin (ARTN) Kinase inhibitors: Vandetanib GFRα4 Agonists:

    CCN family member 2

    CCN family member 2

    CCN_family_member_2

  • Trk receptor

    • InterPro Family

    Erlotinib Gefitinib Grandinin Icotinib Lapatinib Neratinib Osimertinib Vandetanib WHI-P 154 Antibodies: Cetuximab Depatuxizumab Depatuxizumab mafodotin

    Trk receptor

    Trk_receptor

  • Zeneca

    • British multinational pharmaceutical company

    cyclosilicate Tamoxifen Ticagrelor Tixagevimab/cilgavimab Trastuzumab deruxtecan Vandetanib Vaxzevria Ximelagatran Zafirlukast Zolmitriptan Predecessors and acquired

    Zeneca

    Zeneca

  • Sanofi

    • French multinational pharmaceutical and healthcare company

    2015, Genzyme announced that it would acquire the cancer drug Caprelsa (vandetanib) from AstraZeneca for up to $300 million. In the same month, the company

    Sanofi

    Sanofi

    Sanofi

  • Sorafenib

    • Cancer treatment medicine

    inhibitors: Vandetanib GFRα2 Agonists: Neurturin (NRTN) Kinase inhibitors: Vandetanib GFRα3 Agonists: Artemin (ARTN) Kinase inhibitors: Vandetanib GFRα4 Agonists:

    Sorafenib

    Sorafenib

    Sorafenib

  • Amitriptyline

    • Tricyclic antidepressant

    inhibitors: Vandetanib GFRα2 Agonists: Neurturin (NRTN) Kinase inhibitors: Vandetanib GFRα3 Agonists: Artemin (ARTN) Kinase inhibitors: Vandetanib GFRα4 Agonists:

    Amitriptyline

    Amitriptyline

    Amitriptyline

  • Fibroblast growth factor receptor-like 1

    • Protein found in humans

    inhibitors: Vandetanib GFRα2 Agonists: Neurturin (NRTN) Kinase inhibitors: Vandetanib GFRα3 Agonists: Artemin (ARTN) Kinase inhibitors: Vandetanib GFRα4 Agonists:

    Fibroblast growth factor receptor-like 1

    Fibroblast growth factor receptor-like 1

    Fibroblast_growth_factor_receptor-like_1

  • RET proto-oncogene

    • Mammalian protein

    and NCOA4. While older multikinase inhibitors such as cabozantinib or vandetanib showed modest efficacy in targeting RET-driven malignancies, newer selective

    RET proto-oncogene

    RET proto-oncogene

    RET_proto-oncogene

  • Neurotrophic factor receptor

    • Group of protein families

    Erlotinib Gefitinib Grandinin Icotinib Lapatinib Neratinib Osimertinib Vandetanib WHI-P 154 Antibodies: Cetuximab Depatuxizumab Depatuxizumab mafodotin

    Neurotrophic factor receptor

    Neurotrophic_factor_receptor

  • ACD856

    • TrkA and TrkB positive modulator

    Erlotinib Gefitinib Grandinin Icotinib Lapatinib Neratinib Osimertinib Vandetanib WHI-P 154 Antibodies: Cetuximab Depatuxizumab Depatuxizumab mafodotin

    ACD856

    ACD856

  • Semaxanib

    • Chemical compound

    inhibitors: Vandetanib GFRα2 Agonists: Neurturin (NRTN) Kinase inhibitors: Vandetanib GFRα3 Agonists: Artemin (ARTN) Kinase inhibitors: Vandetanib GFRα4 Agonists:

    Semaxanib

    Semaxanib

    Semaxanib

  • Epigen

    • Protein-coding gene in the species Homo sapiens

    inhibitors: Vandetanib GFRα2 Agonists: Neurturin (NRTN) Kinase inhibitors: Vandetanib GFRα3 Agonists: Artemin (ARTN) Kinase inhibitors: Vandetanib GFRα4 Agonists:

    Epigen

    Epigen

    Epigen

  • Murodermin

    • Chemical compound

    inhibitors: Vandetanib GFRα2 Agonists: Neurturin (NRTN) Kinase inhibitors: Vandetanib GFRα3 Agonists: Artemin (ARTN) Kinase inhibitors: Vandetanib GFRα4 Agonists:

    Murodermin

    Murodermin

  • Evinacumab

    • Monoclonal antibody

    inhibitors: Vandetanib GFRα2 Agonists: Neurturin (NRTN) Kinase inhibitors: Vandetanib GFRα3 Agonists: Artemin (ARTN) Kinase inhibitors: Vandetanib GFRα4 Agonists:

    Evinacumab

    Evinacumab

  • Cetuximab

    • Pharmaceutical drug

    Erlotinib Gefitinib Grandinin Icotinib Lapatinib Neratinib Osimertinib Vandetanib WHI-P 154 Antibodies: Cetuximab Depatuxizumab Depatuxizumab mafodotin

    Cetuximab

    Cetuximab

    Cetuximab

  • Selumetinib

    • Chemical compound

    inhibitors: Vandetanib GFRα2 Agonists: Neurturin (NRTN) Kinase inhibitors: Vandetanib GFRα3 Agonists: Artemin (ARTN) Kinase inhibitors: Vandetanib GFRα4 Agonists:

    Selumetinib

    Selumetinib

    Selumetinib

  • Heparin-binding EGF-like growth factor

    • Protein-coding gene in the species Homo sapiens

    inhibitors: Vandetanib GFRα2 Agonists: Neurturin (NRTN) Kinase inhibitors: Vandetanib GFRα3 Agonists: Artemin (ARTN) Kinase inhibitors: Vandetanib GFRα4 Agonists:

    Heparin-binding EGF-like growth factor

    Heparin-binding EGF-like growth factor

    Heparin-binding_EGF-like_growth_factor

  • Trastuzumab deruxtecan

    • Medication

    Erlotinib Gefitinib Grandinin Icotinib Lapatinib Neratinib Osimertinib Vandetanib WHI-P 154 Antibodies: Cetuximab Depatuxizumab Depatuxizumab mafodotin

    Trastuzumab deruxtecan

    Trastuzumab deruxtecan

    Trastuzumab_deruxtecan

  • Repotrectinib

    • Medication

    inhibitors: Vandetanib GFRα2 Agonists: Neurturin (NRTN) Kinase inhibitors: Vandetanib GFRα3 Agonists: Artemin (ARTN) Kinase inhibitors: Vandetanib GFRα4 Agonists:

    Repotrectinib

    Repotrectinib

    Repotrectinib

  • Angiopoietin receptor

    • Cell-surface receptors which bind angiopoietin

    inhibitors: Vandetanib GFRα2 Agonists: Neurturin (NRTN) Kinase inhibitors: Vandetanib GFRα3 Agonists: Artemin (ARTN) Kinase inhibitors: Vandetanib GFRα4 Agonists:

    Angiopoietin receptor

    Angiopoietin receptor

    Angiopoietin_receptor

  • Norwogonin

    • Chemical compound

    inhibitors: Vandetanib GFRα2 Agonists: Neurturin (NRTN) Kinase inhibitors: Vandetanib GFRα3 Agonists: Artemin (ARTN) Kinase inhibitors: Vandetanib GFRα4 Agonists:

    Norwogonin

    Norwogonin

    Norwogonin

  • FGF3

    • Protein-coding gene in humans

    inhibitors: Vandetanib GFRα2 Agonists: Neurturin (NRTN) Kinase inhibitors: Vandetanib GFRα3 Agonists: Artemin (ARTN) Kinase inhibitors: Vandetanib GFRα4 Agonists:

    FGF3

    FGF3

    FGF3

  • Esomeprazole

    • Medication which reduces stomach acid

    cyclosilicate Tamoxifen Ticagrelor Tixagevimab/cilgavimab Trastuzumab deruxtecan Vandetanib Vaxzevria Ximelagatran Zafirlukast Zolmitriptan Predecessors and acquired

    Esomeprazole

    Esomeprazole

    Esomeprazole

  • Pertuzumab/trastuzumab/hyaluronidase

    • Combination drug

    Erlotinib Gefitinib Grandinin Icotinib Lapatinib Neratinib Osimertinib Vandetanib WHI-P 154 Antibodies: Cetuximab Depatuxizumab Depatuxizumab mafodotin

    Pertuzumab/trastuzumab/hyaluronidase

    Pertuzumab/trastuzumab/hyaluronidase

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