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THIO THIP

  • Thio-THIP
  • Pharmaceutical compound

    Thio-THIP, also known as 4,5,6,7-tetrahydroisothiazolo[5,4-c]pyridin-3-ol, is a low-potency GABAA receptor very weak partial agonist or antagonist related

    Thio-THIP

    Thio-THIP

    Thio-THIP

  • Iso-THIP
  • Pharmaceutical compound

    scientific literature by Povl Krogsgaard-Larsen and colleagues by 1979. Aza-THIP Thio-THIP THAZ Frølund B, Ebert B, Kristiansen U, Liljefors T, Krogsgaard-Larsen

    Iso-THIP

    Iso-THIP

    Iso-THIP

  • Gaboxadol
  • Chemical compound

    2016. Analogues of gaboxadol (THIP) include γ-aminobutyric acid (GABA), muscimol, 4-AHP, thio-THIP, aza-THIP, iso-THIP, THAZ, THPO, piperidine-4-sulfonic

    Gaboxadol

    Gaboxadol

    Gaboxadol

  • Aza-THIP
  • Pharmaceutical compound

    colleagues by 1979. Thio-THIP Iso-THIP THAZ Krogsgaard-Larsen P, Frølund B, Liljefors T (2006). "GABAA Agonists and Partial Agonists: THIP (Gaboxadol) as a

    Aza-THIP

    Aza-THIP

    Aza-THIP

  • Thio-4-PIOL
  • Pharmaceutical compound

    have been comprehensively evaluated in terms of functional activities. Thio-THIP Thiomuscimol Piperidine-4-sulphonic acid (P4S) Krall J, Balle T, Krogsgaard-Larsen

    Thio-4-PIOL

    Thio-4-PIOL

    Thio-4-PIOL

  • Muscimol
  • Naturally occurring sedative and hallucinogen

    Compared to muscimol, THIP is generally less potent in the rat. Figure 7 indicates the dose-response-effect of THIP in rats. THIP is active for up to 3

    Muscimol

    Muscimol

    Muscimol

  • THAZ
  • Pharmaceutical compound

    2174/1568026023393525. PMID 12171573. Like thio-THIP, the structurally related THIP analogues, aza-THIP, iso-THIP and THAZ (Fig. 4) are virtually inactive

    THAZ

    THAZ

    THAZ

  • Penicillin
  • Group of antibiotics derived from fungi

    Hydrastine Hyenanchin (mellitoxin) Iso-THIP PHP-501 Pitrazepin Securinine Sinomenine SR-42641 THAZ Thio-4-PIOL Thio-THIP Thiocolchicoside Tutin Negative modulators:

    Penicillin

    Penicillin

    Penicillin

  • Ciprofloxacin
  • Fluoroquinolone antibiotic

    Hydrastine Hyenanchin (mellitoxin) Iso-THIP PHP-501 Pitrazepin Securinine Sinomenine SR-42641 THAZ Thio-4-PIOL Thio-THIP Thiocolchicoside Tutin Negative modulators:

    Ciprofloxacin

    Ciprofloxacin

    Ciprofloxacin

  • Xywav
  • Combination drug

    Hydrastine Hyenanchin (mellitoxin) Iso-THIP PHP-501 Pitrazepin Securinine Sinomenine SR-42641 THAZ Thio-4-PIOL Thio-THIP Thiocolchicoside Tutin Negative modulators:

    Xywav

    Xywav

  • Γ-Hydroxybutyric acid
  • Chemical compound

    Hydrastine Hyenanchin (mellitoxin) Iso-THIP PHP-501 Pitrazepin Securinine Sinomenine SR-42641 THAZ Thio-4-PIOL Thio-THIP Thiocolchicoside Tutin Negative modulators:

    Γ-Hydroxybutyric acid

    Γ-Hydroxybutyric acid

    Γ-Hydroxybutyric_acid

  • GABA reuptake inhibitor
  • Drug class

    (weak) Nipecotic acid NNC 05-2090 NNC-711 SKF-89976A SNAP-5114 THAO Thio-THIP (weak) Thio-THPO THPO (weak) Tiagabine (Gabitril) GABA transaminase inhibitor

    GABA reuptake inhibitor

    GABA reuptake inhibitor

    GABA_reuptake_inhibitor

  • Γ-Valerolactone
  • Chemical compound

    Hydrastine Hyenanchin (mellitoxin) Iso-THIP PHP-501 Pitrazepin Securinine Sinomenine SR-42641 THAZ Thio-4-PIOL Thio-THIP Thiocolchicoside Tutin Negative modulators:

    Γ-Valerolactone

    Γ-Valerolactone

    Γ-Valerolactone

  • Γ-Butyrolactone
  • Chemical compound

    Hydrastine Hyenanchin (mellitoxin) Iso-THIP PHP-501 Pitrazepin Securinine Sinomenine SR-42641 THAZ Thio-4-PIOL Thio-THIP Thiocolchicoside Tutin Negative modulators:

    Γ-Butyrolactone

    Γ-Butyrolactone

    Γ-Butyrolactone

  • Baclofen
  • Muscle relaxant medication

    Hydrastine Hyenanchin (mellitoxin) Iso-THIP PHP-501 Pitrazepin Securinine Sinomenine SR-42641 THAZ Thio-4-PIOL Thio-THIP Thiocolchicoside Tutin Negative modulators:

    Baclofen

    Baclofen

    Baclofen

  • Furosemide
  • Loop diuretic medication

    Hydrastine Hyenanchin (mellitoxin) Iso-THIP PHP-501 Pitrazepin Securinine Sinomenine SR-42641 THAZ Thio-4-PIOL Thio-THIP Thiocolchicoside Tutin Negative modulators:

    Furosemide

    Furosemide

    Furosemide

  • RDX
  • Explosive chemical compound

    Hydrastine Hyenanchin (mellitoxin) Iso-THIP PHP-501 Pitrazepin Securinine Sinomenine SR-42641 THAZ Thio-4-PIOL Thio-THIP Thiocolchicoside Tutin Negative modulators:

    RDX

    RDX

    RDX

  • Tetramethylenedisulfotetramine
  • Chemical compound

    Hydrastine Hyenanchin (mellitoxin) Iso-THIP PHP-501 Pitrazepin Securinine Sinomenine SR-42641 THAZ Thio-4-PIOL Thio-THIP Thiocolchicoside Tutin Negative modulators:

    Tetramethylenedisulfotetramine

    Tetramethylenedisulfotetramine

    Tetramethylenedisulfotetramine

  • GABAergic
  • Affecting GABA systems in the brain

    Hydrastine Hyenanchin (mellitoxin) Iso-THIP PHP-501 Pitrazepin Securinine Sinomenine SR-42641 THAZ Thio-4-PIOL Thio-THIP Thiocolchicoside Tutin Negative modulators:

    GABAergic

    GABAergic

  • Levofloxacin
  • Antibiotic

    Hydrastine Hyenanchin (mellitoxin) Iso-THIP PHP-501 Pitrazepin Securinine Sinomenine SR-42641 THAZ Thio-4-PIOL Thio-THIP Thiocolchicoside Tutin Negative modulators:

    Levofloxacin

    Levofloxacin

    Levofloxacin

  • Valeric acid
  • Carboxylic acid – CH3(CH2)3COOH

    Hydrastine Hyenanchin (mellitoxin) Iso-THIP PHP-501 Pitrazepin Securinine Sinomenine SR-42641 THAZ Thio-4-PIOL Thio-THIP Thiocolchicoside Tutin Negative modulators:

    Valeric acid

    Valeric acid

    Valeric_acid

  • GABAA receptor agonist
  • Hallucinogenic drug

    acid (GABOB), muscimol (found in Amanita muscaria mushrooms), gaboxadol (THIP), and progabide, among others. High-efficacy GABAA receptor agonists have

    GABAA receptor agonist

    GABAA receptor agonist

    GABAA_receptor_agonist

  • Glutamine
  • Amino acid

    Hydrastine Hyenanchin (mellitoxin) Iso-THIP PHP-501 Pitrazepin Securinine Sinomenine SR-42641 THAZ Thio-4-PIOL Thio-THIP Thiocolchicoside Tutin Negative modulators:

    Glutamine

    Glutamine

    Glutamine

  • GABA receptor agonist
  • Category of drug

    Benzodiazepines Dihydromuscimol Etomidate GABA Gabamide GABOB Gaboxadol (THIP) Ibotenic acid Imidazole-4-acetic acid (IAA) Isoguvacine Isonipecotic acid

    GABA receptor agonist

    GABA receptor agonist

    GABA_receptor_agonist

  • Flumazenil
  • GABA receptor antagonist drug and benzodiazepine antidote

    Hydrastine Hyenanchin (mellitoxin) Iso-THIP PHP-501 Pitrazepin Securinine Sinomenine SR-42641 THAZ Thio-4-PIOL Thio-THIP Thiocolchicoside Tutin Negative modulators:

    Flumazenil

    Flumazenil

    Flumazenil

  • Phenytoin
  • Anti-seizure medication

    Hydrastine Hyenanchin (mellitoxin) Iso-THIP PHP-501 Pitrazepin Securinine Sinomenine SR-42641 THAZ Thio-4-PIOL Thio-THIP Thiocolchicoside Tutin Negative modulators:

    Phenytoin

    Phenytoin

    Phenytoin

  • Fipronil
  • Chemical compound

    Hydrastine Hyenanchin (mellitoxin) Iso-THIP PHP-501 Pitrazepin Securinine Sinomenine SR-42641 THAZ Thio-4-PIOL Thio-THIP Thiocolchicoside Tutin Negative modulators:

    Fipronil

    Fipronil

    Fipronil

  • Imidazoleacetic acid
  • Pharmaceutical compound

    maximal response of THIP and IAA are qualitatively the same as that of P4S. [...] Fig. (7). Subunit dependent efficacy of isoguvacine, THIP, P4S and IAA. [

    Imidazoleacetic acid

    Imidazoleacetic acid

    Imidazoleacetic_acid

  • Pentylenetetrazol
  • Chemical compound

    Hydrastine Hyenanchin (mellitoxin) Iso-THIP PHP-501 Pitrazepin Securinine Sinomenine SR-42641 THAZ Thio-4-PIOL Thio-THIP Thiocolchicoside Tutin Negative modulators:

    Pentylenetetrazol

    Pentylenetetrazol

    Pentylenetetrazol

  • Picamilon
  • Chemical compound

    Hydrastine Hyenanchin (mellitoxin) Iso-THIP PHP-501 Pitrazepin Securinine Sinomenine SR-42641 THAZ Thio-4-PIOL Thio-THIP Thiocolchicoside Tutin Negative modulators:

    Picamilon

    Picamilon

    Picamilon

  • Clarithromycin
  • Antibiotic medication

    Hydrastine Hyenanchin (mellitoxin) Iso-THIP PHP-501 Pitrazepin Securinine Sinomenine SR-42641 THAZ Thio-4-PIOL Thio-THIP Thiocolchicoside Tutin Negative modulators:

    Clarithromycin

    Clarithromycin

    Clarithromycin

  • Valproate pivoxil
  • Chemical compound

    Nipecotic acid NNC 05-2090 NO-711 Riluzole SKF-89976A SNAP-5114 TACA THAO Thio-THIP Thio-THPO THPO Tiagabine VIAATTooltip Vesicular inhibitory amino acid transporter

    Valproate pivoxil

    Valproate pivoxil

    Valproate_pivoxil

  • Amino acid transporter
  • Membrane transport proteins

    Nipecotic acid NNC 05-2090 NO-711 Riluzole SKF-89976A SNAP-5114 TACA THAO Thio-THIP Thio-THPO THPO Tiagabine VIAATTooltip Vesicular inhibitory amino acid transporter

    Amino acid transporter

    Amino_acid_transporter

  • Oenanthotoxin
  • Chemical compound

    Hydrastine Hyenanchin (mellitoxin) Iso-THIP PHP-501 Pitrazepin Securinine Sinomenine SR-42641 THAZ Thio-4-PIOL Thio-THIP Thiocolchicoside Tutin Negative modulators:

    Oenanthotoxin

    Oenanthotoxin

    Oenanthotoxin

  • Dihydromuscimol
  • Pharmaceutical compound

    Gaboxadol (THIP) 4-AHP 4-PIOL Krogsgaard-Larsen P, Frølund B, Liljefors T, Ebert B (October 2004). "GABAA agonists and partial agonists: THIP (Gaboxadol)

    Dihydromuscimol

    Dihydromuscimol

    Dihydromuscimol

  • 1,4-Butanediol
  • One of four stable isomers of butanediol

    Hydrastine Hyenanchin (mellitoxin) Iso-THIP PHP-501 Pitrazepin Securinine Sinomenine SR-42641 THAZ Thio-4-PIOL Thio-THIP Thiocolchicoside Tutin Negative modulators:

    1,4-Butanediol

    1,4-Butanediol

    1,4-Butanediol

  • Valiloxybate
  • Pharmaceutical compound

    Hydrastine Hyenanchin (mellitoxin) Iso-THIP PHP-501 Pitrazepin Securinine Sinomenine SR-42641 THAZ Thio-4-PIOL Thio-THIP Thiocolchicoside Tutin Negative modulators:

    Valiloxybate

    Valiloxybate

    Valiloxybate

  • Desflurane
  • Inhalational anesthesia medication

    Hydrastine Hyenanchin (mellitoxin) Iso-THIP PHP-501 Pitrazepin Securinine Sinomenine SR-42641 THAZ Thio-4-PIOL Thio-THIP Thiocolchicoside Tutin Negative modulators:

    Desflurane

    Desflurane

    Desflurane

  • Cicutoxin
  • Chemical compound

    Hydrastine Hyenanchin (mellitoxin) Iso-THIP PHP-501 Pitrazepin Securinine Sinomenine SR-42641 THAZ Thio-4-PIOL Thio-THIP Thiocolchicoside Tutin Negative modulators:

    Cicutoxin

    Cicutoxin

    Cicutoxin

  • ADX-71441
  • Chemical compound

    Hydrastine Hyenanchin (mellitoxin) Iso-THIP PHP-501 Pitrazepin Securinine Sinomenine SR-42641 THAZ Thio-4-PIOL Thio-THIP Thiocolchicoside Tutin Negative modulators:

    ADX-71441

    ADX-71441

    ADX-71441

  • GABA
  • Main inhibitory neurotransmitter in the mammalian brain

    Hydrastine Hyenanchin (mellitoxin) Iso-THIP PHP-501 Pitrazepin Securinine Sinomenine SR-42641 THAZ Thio-4-PIOL Thio-THIP Thiocolchicoside Tutin Negative modulators:

    GABA

    GABA

    GABA

  • Coriamyrtin
  • Convulsant toxin

    Hydrastine Hyenanchin (mellitoxin) Iso-THIP PHP-501 Pitrazepin Securinine Sinomenine SR-42641 THAZ Thio-4-PIOL Thio-THIP Thiocolchicoside Tutin Negative modulators:

    Coriamyrtin

    Coriamyrtin

    Coriamyrtin

  • Β-Alanine
  • Chemical compound

    Nipecotic acid NNC 05-2090 NO-711 Riluzole SKF-89976A SNAP-5114 TACA THAO Thio-THIP Thio-THPO THPO Tiagabine VIAATTooltip Vesicular inhibitory amino acid transporter

    Β-Alanine

    Β-Alanine

    Β-Alanine

  • Methylglyoxal
  • Chemical compound

    Hydrastine Hyenanchin (mellitoxin) Iso-THIP PHP-501 Pitrazepin Securinine Sinomenine SR-42641 THAZ Thio-4-PIOL Thio-THIP Thiocolchicoside Tutin Negative modulators:

    Methylglyoxal

    Methylglyoxal

    Methylglyoxal

  • 3-Methyl-GABA
  • Chemical compound

    Nipecotic acid NNC 05-2090 NO-711 Riluzole SKF-89976A SNAP-5114 TACA THAO Thio-THIP Thio-THPO THPO Tiagabine VIAATTooltip Vesicular inhibitory amino acid transporter

    3-Methyl-GABA

    3-Methyl-GABA

    3-Methyl-GABA

  • Isoflavonoid
  • Class of chemical compound

    Hydrastine Hyenanchin (mellitoxin) Iso-THIP PHP-501 Pitrazepin Securinine Sinomenine SR-42641 THAZ Thio-4-PIOL Thio-THIP Thiocolchicoside Tutin Negative modulators:

    Isoflavonoid

    Isoflavonoid

    Isoflavonoid

  • EBOB
  • Chemical compound

    Hydrastine Hyenanchin (mellitoxin) Iso-THIP PHP-501 Pitrazepin Securinine Sinomenine SR-42641 THAZ Thio-4-PIOL Thio-THIP Thiocolchicoside Tutin Negative modulators:

    EBOB

    EBOB

    EBOB

  • 4-AHP
  • Pharmaceutical compound

    receptor agonist than γ-aminobutyric acid (GABA), muscimol, or gaboxadol (THIP) (e.g., ~30-fold lower affinity and ~24-fold lower activational potency than

    4-AHP

    4-AHP

    4-AHP

  • Gabaculine
  • Chemical compound

    Nipecotic acid NNC 05-2090 NO-711 Riluzole SKF-89976A SNAP-5114 TACA THAO Thio-THIP Thio-THPO THPO Tiagabine VIAATTooltip Vesicular inhibitory amino acid transporter

    Gabaculine

    Gabaculine

    Gabaculine

  • Glufimet
  • Chemical compound

    Hydrastine Hyenanchin (mellitoxin) Iso-THIP PHP-501 Pitrazepin Securinine Sinomenine SR-42641 THAZ Thio-4-PIOL Thio-THIP Thiocolchicoside Tutin Negative modulators:

    Glufimet

    Glufimet

    Glufimet

  • Ibotenic acid
  • Naturally occurring glutamate receptor agonist neurotoxin

    Hydrastine Hyenanchin (mellitoxin) Iso-THIP PHP-501 Pitrazepin Securinine Sinomenine SR-42641 THAZ Thio-4-PIOL Thio-THIP Thiocolchicoside Tutin Negative modulators:

    Ibotenic acid

    Ibotenic acid

    Ibotenic_acid

  • Amfecloral
  • Withdrawn appetite suppressant drug

    Hydrastine Hyenanchin (mellitoxin) Iso-THIP PHP-501 Pitrazepin Securinine Sinomenine SR-42641 THAZ Thio-4-PIOL Thio-THIP Thiocolchicoside Tutin Negative modulators:

    Amfecloral

    Amfecloral

    Amfecloral

  • Amentoflavone
  • Chemical compound

    Hydrastine Hyenanchin (mellitoxin) Iso-THIP PHP-501 Pitrazepin Securinine Sinomenine SR-42641 THAZ Thio-4-PIOL Thio-THIP Thiocolchicoside Tutin Negative modulators:

    Amentoflavone

    Amentoflavone

    Amentoflavone

  • Flurothyl
  • Chemical compound

    Hydrastine Hyenanchin (mellitoxin) Iso-THIP PHP-501 Pitrazepin Securinine Sinomenine SR-42641 THAZ Thio-4-PIOL Thio-THIP Thiocolchicoside Tutin Negative modulators:

    Flurothyl

    Flurothyl

    Flurothyl

  • Tiagabine
  • Anticonvulsant medication

    diverse and complex effects on SWA. GABA agonists, such as muscimol and THIP (Gaboxadol) and the GABA uptake inhibitor tiagabine, increase SWA and SWS

    Tiagabine

    Tiagabine

    Tiagabine

  • Imipenem
  • Carbapenem antibiotic

    Hydrastine Hyenanchin (mellitoxin) Iso-THIP PHP-501 Pitrazepin Securinine Sinomenine SR-42641 THAZ Thio-4-PIOL Thio-THIP Thiocolchicoside Tutin Negative modulators:

    Imipenem

    Imipenem

    Imipenem

  • Γ-Amino-β-hydroxybutyric acid
  • Anticonvulsant drug

    Hydrastine Hyenanchin (mellitoxin) Iso-THIP PHP-501 Pitrazepin Securinine Sinomenine SR-42641 THAZ Thio-4-PIOL Thio-THIP Thiocolchicoside Tutin Negative modulators:

    Γ-Amino-β-hydroxybutyric acid

    Γ-Amino-β-hydroxybutyric acid

    Γ-Amino-β-hydroxybutyric_acid

  • Honokiol
  • Chemical compound

    Hydrastine Hyenanchin (mellitoxin) Iso-THIP PHP-501 Pitrazepin Securinine Sinomenine SR-42641 THAZ Thio-4-PIOL Thio-THIP Thiocolchicoside Tutin Negative modulators:

    Honokiol

    Honokiol

    Honokiol

  • Picrotoxin
  • Chemical compound

    Hydrastine Hyenanchin (mellitoxin) Iso-THIP PHP-501 Pitrazepin Securinine Sinomenine SR-42641 THAZ Thio-4-PIOL Thio-THIP Thiocolchicoside Tutin Negative modulators:

    Picrotoxin

    Picrotoxin

    Picrotoxin

  • Dihydropicrotoxinin
  • Chemical compound

    Hydrastine Hyenanchin (mellitoxin) Iso-THIP PHP-501 Pitrazepin Securinine Sinomenine SR-42641 THAZ Thio-4-PIOL Thio-THIP Thiocolchicoside Tutin Negative modulators:

    Dihydropicrotoxinin

    Dihydropicrotoxinin

    Dihydropicrotoxinin

  • Bicuculline
  • Chemical compound

    Hydrastine Hyenanchin (mellitoxin) Iso-THIP PHP-501 Pitrazepin Securinine Sinomenine SR-42641 THAZ Thio-4-PIOL Thio-THIP Thiocolchicoside Tutin Negative modulators:

    Bicuculline

    Bicuculline

    Bicuculline

  • Phenibut
  • CNS depressant medication

    Hydrastine Hyenanchin (mellitoxin) Iso-THIP PHP-501 Pitrazepin Securinine Sinomenine SR-42641 THAZ Thio-4-PIOL Thio-THIP Thiocolchicoside Tutin Negative modulators:

    Phenibut

    Phenibut

    Phenibut

  • Bicyclic phosphate
  • Class of chemical compounds

    Hydrastine Hyenanchin (mellitoxin) Iso-THIP PHP-501 Pitrazepin Securinine Sinomenine SR-42641 THAZ Thio-4-PIOL Thio-THIP Thiocolchicoside Tutin Negative modulators:

    Bicyclic phosphate

    Bicyclic_phosphate

  • Butyric acid
  • Chemical compound (CH3CH2CH2COOH)

    Nipecotic acid NNC 05-2090 NO-711 Riluzole SKF-89976A SNAP-5114 TACA THAO Thio-THIP Thio-THPO THPO Tiagabine VIAATTooltip Vesicular inhibitory amino acid transporter

    Butyric acid

    Butyric acid

    Butyric_acid

  • Piperidine-4-sulfonic acid
  • Pharmaceutical compound

    contrast to other GABAA receptor agonists like isoguvacine and gaboxadol (THIP), which show broadly higher activational efficacies at GABAA receptors of

    Piperidine-4-sulfonic acid

    Piperidine-4-sulfonic acid

    Piperidine-4-sulfonic_acid

  • GABAA receptor
  • Ionotropic receptor and ligand-gated ion channel

    Hydrastine Hyenanchin (mellitoxin) Iso-THIP PHP-501 Pitrazepin Securinine Sinomenine SR-42641 THAZ Thio-4-PIOL Thio-THIP Thiocolchicoside Tutin Negative modulators:

    GABAA receptor

    GABAA receptor

    GABAA_receptor

  • PNV-001
  • Pharmaceutical compound

    Hydrastine Hyenanchin (mellitoxin) Iso-THIP PHP-501 Pitrazepin Securinine Sinomenine SR-42641 THAZ Thio-4-PIOL Thio-THIP Thiocolchicoside Tutin Negative modulators:

    PNV-001

    PNV-001

  • Enzalutamide
  • Antiandrogen medication used in treatment of prostate cancer

    Hydrastine Hyenanchin (mellitoxin) Iso-THIP PHP-501 Pitrazepin Securinine Sinomenine SR-42641 THAZ Thio-4-PIOL Thio-THIP Thiocolchicoside Tutin Negative modulators:

    Enzalutamide

    Enzalutamide

    Enzalutamide

  • Α3IA
  • Chemical compound, anxiogenic

    Hydrastine Hyenanchin (mellitoxin) Iso-THIP PHP-501 Pitrazepin Securinine Sinomenine SR-42641 THAZ Thio-4-PIOL Thio-THIP Thiocolchicoside Tutin Negative modulators:

    Α3IA

    Α3IA

    Α3IA

  • Ofloxacin
  • Antibiotic to treat bacterial infections

    Hydrastine Hyenanchin (mellitoxin) Iso-THIP PHP-501 Pitrazepin Securinine Sinomenine SR-42641 THAZ Thio-4-PIOL Thio-THIP Thiocolchicoside Tutin Negative modulators:

    Ofloxacin

    Ofloxacin

    Ofloxacin

  • N-Benzoyl-GABA
  • Pharmaceutical compound

    Hydrastine Hyenanchin (mellitoxin) Iso-THIP PHP-501 Pitrazepin Securinine Sinomenine SR-42641 THAZ Thio-4-PIOL Thio-THIP Thiocolchicoside Tutin Negative modulators:

    N-Benzoyl-GABA

    N-Benzoyl-GABA

    N-Benzoyl-GABA

  • Dieldrin
  • Chemical compound

    Hydrastine Hyenanchin (mellitoxin) Iso-THIP PHP-501 Pitrazepin Securinine Sinomenine SR-42641 THAZ Thio-4-PIOL Thio-THIP Thiocolchicoside Tutin Negative modulators:

    Dieldrin

    Dieldrin

    Dieldrin

  • IPTBO
  • Chemical compound

    Hydrastine Hyenanchin (mellitoxin) Iso-THIP PHP-501 Pitrazepin Securinine Sinomenine SR-42641 THAZ Thio-4-PIOL Thio-THIP Thiocolchicoside Tutin Negative modulators:

    IPTBO

    IPTBO

    IPTBO

  • Bafilomycin
  • Chemical compound

    Nipecotic acid NNC 05-2090 NO-711 Riluzole SKF-89976A SNAP-5114 TACA THAO Thio-THIP Thio-THPO THPO Tiagabine VIAATTooltip Vesicular inhibitory amino acid transporter

    Bafilomycin

    Bafilomycin

    Bafilomycin

  • 5β-Dihydroprogesterone
  • Chemical compound

    Hydrastine Hyenanchin (mellitoxin) Iso-THIP PHP-501 Pitrazepin Securinine Sinomenine SR-42641 THAZ Thio-4-PIOL Thio-THIP Thiocolchicoside Tutin Negative modulators:

    5β-Dihydroprogesterone

    5β-Dihydroprogesterone

    5β-Dihydroprogesterone

  • Valinomycin
  • Chemical compound

    Nipecotic acid NNC 05-2090 NO-711 Riluzole SKF-89976A SNAP-5114 TACA THAO Thio-THIP Thio-THPO THPO Tiagabine VIAATTooltip Vesicular inhibitory amino acid transporter

    Valinomycin

    Valinomycin

    Valinomycin

  • Sodium oxybate
  • Medication to treat symptoms of narcolepsy

    Hydrastine Hyenanchin (mellitoxin) Iso-THIP PHP-501 Pitrazepin Securinine Sinomenine SR-42641 THAZ Thio-4-PIOL Thio-THIP Thiocolchicoside Tutin Negative modulators:

    Sodium oxybate

    Sodium oxybate

    Sodium_oxybate

  • Nefiracetam
  • Chemical compound

    Hydrastine Hyenanchin (mellitoxin) Iso-THIP PHP-501 Pitrazepin Securinine Sinomenine SR-42641 THAZ Thio-4-PIOL Thio-THIP Thiocolchicoside Tutin Negative modulators:

    Nefiracetam

    Nefiracetam

    Nefiracetam

  • CPP-115
  • Experimental drug

    Nipecotic acid NNC 05-2090 NO-711 Riluzole SKF-89976A SNAP-5114 TACA THAO Thio-THIP Thio-THPO THPO Tiagabine VIAATTooltip Vesicular inhibitory amino acid transporter

    CPP-115

    CPP-115

    CPP-115

  • Nicardipine
  • Antihypertensive drug of the calcium channel blocker class

    Hydrastine Hyenanchin (mellitoxin) Iso-THIP PHP-501 Pitrazepin Securinine Sinomenine SR-42641 THAZ Thio-4-PIOL Thio-THIP Thiocolchicoside Tutin Negative modulators:

    Nicardipine

    Nicardipine

    Nicardipine

  • GABA transaminase inhibitor
  • Nipecotic acid NNC 05-2090 NO-711 Riluzole SKF-89976A SNAP-5114 TACA THAO Thio-THIP Thio-THPO THPO Tiagabine VIAATTooltip Vesicular inhibitory amino acid transporter

    GABA transaminase inhibitor

    GABA transaminase inhibitor

    GABA_transaminase_inhibitor

  • GABRA2
  • Protein in humans

    Hydrastine Hyenanchin (mellitoxin) Iso-THIP PHP-501 Pitrazepin Securinine Sinomenine SR-42641 THAZ Thio-4-PIOL Thio-THIP Thiocolchicoside Tutin Negative modulators:

    GABRA2

    GABRA2

    GABRA2

  • GABA analogue
  • Class of drugs

    Hydrastine Hyenanchin (mellitoxin) Iso-THIP PHP-501 Pitrazepin Securinine Sinomenine SR-42641 THAZ Thio-4-PIOL Thio-THIP Thiocolchicoside Tutin Negative modulators:

    GABA analogue

    GABA analogue

    GABA_analogue

  • Tolibut
  • Chemical compound

    Hydrastine Hyenanchin (mellitoxin) Iso-THIP PHP-501 Pitrazepin Securinine Sinomenine SR-42641 THAZ Thio-4-PIOL Thio-THIP Thiocolchicoside Tutin Negative modulators:

    Tolibut

    Tolibut

    Tolibut

  • Cyclothiazide
  • Chemical compound

    Hydrastine Hyenanchin (mellitoxin) Iso-THIP PHP-501 Pitrazepin Securinine Sinomenine SR-42641 THAZ Thio-4-PIOL Thio-THIP Thiocolchicoside Tutin Negative modulators:

    Cyclothiazide

    Cyclothiazide

    Cyclothiazide

  • GABAA receptor negative allosteric modulator
  • Drug class

    Hydrastine Hyenanchin (mellitoxin) Iso-THIP PHP-501 Pitrazepin Securinine Sinomenine SR-42641 THAZ Thio-4-PIOL Thio-THIP Thiocolchicoside Tutin Negative modulators:

    GABAA receptor negative allosteric modulator

    GABAA_receptor_negative_allosteric_modulator

  • Homotaurine
  • Chemical compound

    Hydrastine Hyenanchin (mellitoxin) Iso-THIP PHP-501 Pitrazepin Securinine Sinomenine SR-42641 THAZ Thio-4-PIOL Thio-THIP Thiocolchicoside Tutin Negative modulators:

    Homotaurine

    Homotaurine

    Homotaurine

  • INDV-1000
  • Pharmaceutical compound

    Hydrastine Hyenanchin (mellitoxin) Iso-THIP PHP-501 Pitrazepin Securinine Sinomenine SR-42641 THAZ Thio-4-PIOL Thio-THIP Thiocolchicoside Tutin Negative modulators:

    INDV-1000

    INDV-1000

  • Pregnanolone
  • Chemical compound

    Hydrastine Hyenanchin (mellitoxin) Iso-THIP PHP-501 Pitrazepin Securinine Sinomenine SR-42641 THAZ Thio-4-PIOL Thio-THIP Thiocolchicoside Tutin Negative modulators:

    Pregnanolone

    Pregnanolone

    Pregnanolone

  • N-Acetyl-γ-aminobutyric acid
  • Endogenous GABA precursor

    Hydrastine Hyenanchin (mellitoxin) Iso-THIP PHP-501 Pitrazepin Securinine Sinomenine SR-42641 THAZ Thio-4-PIOL Thio-THIP Thiocolchicoside Tutin Negative modulators:

    N-Acetyl-γ-aminobutyric acid

    N-Acetyl-γ-aminobutyric acid

    N-Acetyl-γ-aminobutyric_acid

  • Quisqualamine
  • Pharmaceutical compound

    Hydrastine Hyenanchin (mellitoxin) Iso-THIP PHP-501 Pitrazepin Securinine Sinomenine SR-42641 THAZ Thio-4-PIOL Thio-THIP Thiocolchicoside Tutin Negative modulators:

    Quisqualamine

    Quisqualamine

    Quisqualamine

  • Pregnenolone sulfate
  • Chemical compound

    Hydrastine Hyenanchin (mellitoxin) Iso-THIP PHP-501 Pitrazepin Securinine Sinomenine SR-42641 THAZ Thio-4-PIOL Thio-THIP Thiocolchicoside Tutin Negative modulators:

    Pregnenolone sulfate

    Pregnenolone sulfate

    Pregnenolone_sulfate

  • Ro15-4513
  • Chemical compound

    Hydrastine Hyenanchin (mellitoxin) Iso-THIP PHP-501 Pitrazepin Securinine Sinomenine SR-42641 THAZ Thio-4-PIOL Thio-THIP Thiocolchicoside Tutin Negative modulators:

    Ro15-4513

    Ro15-4513

    Ro15-4513

  • Bilobalide
  • Chemical compound

    Hydrastine Hyenanchin (mellitoxin) Iso-THIP PHP-501 Pitrazepin Securinine Sinomenine SR-42641 THAZ Thio-4-PIOL Thio-THIP Thiocolchicoside Tutin Negative modulators:

    Bilobalide

    Bilobalide

    Bilobalide

  • Hopantenic acid
  • Chemical compound

    Hydrastine Hyenanchin (mellitoxin) Iso-THIP PHP-501 Pitrazepin Securinine Sinomenine SR-42641 THAZ Thio-4-PIOL Thio-THIP Thiocolchicoside Tutin Negative modulators:

    Hopantenic acid

    Hopantenic acid

    Hopantenic_acid

  • Dehydroepiandrosterone
  • Chemical compound

    Hydrastine Hyenanchin (mellitoxin) Iso-THIP PHP-501 Pitrazepin Securinine Sinomenine SR-42641 THAZ Thio-4-PIOL Thio-THIP Thiocolchicoside Tutin Negative modulators:

    Dehydroepiandrosterone

    Dehydroepiandrosterone

    Dehydroepiandrosterone

  • JZP-386
  • Pharmaceutical compound

    Hydrastine Hyenanchin (mellitoxin) Iso-THIP PHP-501 Pitrazepin Securinine Sinomenine SR-42641 THAZ Thio-4-PIOL Thio-THIP Thiocolchicoside Tutin Negative modulators:

    JZP-386

    JZP-386

    JZP-386

  • GABAA-rho receptor
  • Class of transport proteins

    Muscimol Mixed GABAA-ρ / GABAB antagonists ZAPA ((Z)-3-[(Aminoiminomethyl)thio]prop-2-enoic acid) SKF-97541 (3-Aminopropyl(methyl)phosphinic acid) CGP-36742

    GABAA-rho receptor

    GABAA-rho_receptor

  • GABRA3
  • Protein-coding gene in humans

    Hydrastine Hyenanchin (mellitoxin) Iso-THIP PHP-501 Pitrazepin Securinine Sinomenine SR-42641 THAZ Thio-4-PIOL Thio-THIP Thiocolchicoside Tutin Negative modulators:

    GABRA3

    GABRA3

    GABRA3

  • Phenylsilatrane
  • Chemical compound

    Hydrastine Hyenanchin (mellitoxin) Iso-THIP PHP-501 Pitrazepin Securinine Sinomenine SR-42641 THAZ Thio-4-PIOL Thio-THIP Thiocolchicoside Tutin Negative modulators:

    Phenylsilatrane

    Phenylsilatrane

    Phenylsilatrane

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