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See searches and references containing THE MUTATIONS!THE MUTATIONS
1974 British-American film by Jack Cardiff
The Mutations (also known as The Mutation, The Freaks, and The Freakmaker) is a low-budget 1974 British-American science fiction/horror film directed by
The_Mutations
Alteration in the nucleotide sequence of a genome
synthesis). Mutations may also result from substitution, insertion or deletion of segments of DNA due to mobile genetic elements. Mutations may or may
Mutation
Inherited genetic variation
death (apoptosis). A germline mutation can also occur due to exogenous factors. Similar to somatic mutations, germline mutations can be caused by exposure
Germline_mutation
Medical condition
and BRCA2 mutations (with BRCA1 mutations being slightly more common than BRCA2 mutations), but the impact on women with the gene mutation is more profound
BRCA_mutation
Mutation that shifts codon alignment
frameshift mutations. Reverse mutations occur which change the mutated sequence back to the original wild type sequence. Another possibility for mutation correction
Frameshift_mutation
Rate at which mutations occur during some unit of time
single type of mutation; there are many different types of mutations. Mutation rates are given for specific classes of mutations. Point mutations are a class
Mutation_rate
Topics referred to by the same term
album by Battery "Mutations", a song by Salt the Wound from their 2009 album, Ares Mutation, a 2005 album by Donna Williams "Mutations", a song by Nilüfer
Mutation_(disambiguation)
Science of genes, heredity and variation
phenotypes to appear. Most mutations have little effect on an organism's phenotype, health, or reproductive fitness. Mutations that do have an effect are
Genetics
Type of mutation in a DNA sequence
the protein are affected. As nonsense mutations lead to premature termination of polypeptide chains, they are also called chain termination mutations
Nonsense_mutation
1998 studio album by Beck
Type Mutations Beck in the "Search:" field. "American album certifications – Beck – Mutations". Recording Industry Association of America. Mutations at
Mutations_(Beck_album)
Genetic point mutation that results in an amino acid change in a protein
substitution. Missense mutations change amino acids, which in turn alter proteins and may alter a protein's function or structure. These mutations may arise spontaneously
Missense_mutation
Consonant mutation in the Breton language
The mutations are divided into four main groups, according to the changes they cause: soft mutation (Breton kemmadurioù dre vlotaat), hard mutation (kemmadurioù
Breton_mutations
Genetic mutation not inherited from a parent
of point mutations; silent mutations, missense mutations and nonsense mutations. Silent mutation A silent mutation occurs when a change in the nucleotide
De_novo_mutation
Replacement, insertion, or deletion of a single DNA or RNA nucleotide
acid that the nucleotides code for. Point mutations may arise from spontaneous mutations that occur during DNA replication. The rate of mutation may be increased
Point_mutation
even if all mutations in a tumor were caused by UV from sunlight, one quarter of the mutations are expected to not be UV signature mutations. A second carcinogen
Mutational_signatures
Type of mutation on somatic cell
or gametocyte. Unlike germline mutations, which can be passed on to the descendants of an organism, somatic mutations are not usually transmitted to descendants
Somatic_mutation
Sound change happening in linguistics
Breton have four (if mixed mutations are counted). Cornish and Breton have so-called mixed mutations; a trigger causes one mutation to some sounds and another
Consonant_mutation
Mutation acquired during an organism's lifespan
gametes. Mutations that occur after the zygote has formed can be caused by a variety of sources that fall under two classes: spontaneous mutations and induced
Postzygotic_mutation
One of several alternatives to evolution by natural selection
individuals" by directed mass mutations. In 1923, the botanist John Christopher Willis proposed that species were formed by large mutations, not gradual evolution
Mutationism
Adaptive mutation, also called directed mutation or directed mutagenesis is a controversial evolutionary theory. It posits that mutations, or genetic changes
Adaptive_mutation
Type of evolutionary extinction vortex
experiencing mutational meltdown is trapped in a downward spiral and will go extinct if the phenomenon lasts for some time. Usually, the deleterious mutations would
Mutational_meltdown
DNA mutation with no observable effect on an organism's phenotype
Silent mutations, also called synonymous or samesense mutations, are mutations in DNA that do not have an observable effect on the organism's phenotype
Silent_mutation
Changes to DNA with no overall impact
genetics, mutations in which natural selection does not affect the spread of the mutation in a species are termed neutral mutations. Neutral mutations that
Neutral_mutation
Medical condition
Blok–Campeau syndrome is a rare autosomal genetic disorder caused by mutations in the CHD3 gene. It is characterized by impaired intellectual development
Snijders Blok–Campeau syndrome
Snijders_Blok–Campeau_syndrome
Codon that marks the end of a protein-coding sequence
nonstop mutation lose their function due to their extreme length and the impact on normal folding. Nonstop mutations differ from nonsense mutations in that
Stop_codon
1979 Italian film
Island of the Fishmen or Island of Mutations (Italian: L'isola degli uomini pesce) is a 1979 action-horror film directed by Sergio Martino, starring Barbara
Island_of_the_Fishmen
Type of mutation
Genetic suppression therefore restores the phenotype seen prior to the original background mutation. Suppressor mutations are useful for identifying new genetic
Suppressor_mutation
Word initial consonantal sound changes in Irish
consonant mutations. These mutations affect the initial consonant of a word under specific morphological and syntactic conditions. The mutations are an important
Irish_initial_mutations
1943 experiment into rate of mutations
The Luria–Delbrück experiment (1943) (also called the Fluctuation Test) demonstrated that in bacteria, genetic mutations arise in the absence of selective
Luria–Delbrück_experiment
Genetic condition involving hearing loss and depigmentation
with combined type 1 and type 2A mutations (PAX3 and MITF), from parents having only single mutations in MITF or PAX3. The child had increased pigment-related
Waardenburg_syndrome
Health problem from genome abnormalities
the non-mutated gene product within the same cell. X-linked dominant disorders are caused by mutations in genes on the X chromosome. Only a few disorders
Genetic_disorder
1994 compilation album by Fight
Mutations is a compilation album released by the heavy metal band Fight in 1994. It features live recordings alongside studio remixes of songs from War
Mutations_(Fight_album)
Group of comics characters
producing a protein stimulating chemical signals which induce mutations on other genes. Mutations are depicted as generally manifesting during adolescence
Mutant_(Marvel_Comics)
mutations and replication-independent mutations. Therefore, there are two kinds of mutation mechanisms to explain the phenomenon of male mutation bias
Mutation_bias
Genes regulating the development of anatomical structures in various organisms
patterning. Mutations in homeotic genes cause displaced body parts (homeosis), such as antennae growing at the posterior of the fly instead of at the head.
Homeotic_gene
1992 EP by Orbital
Mutations, subtitled "From L.P. C.D. M.C.", is an EP by English electronic music duo Orbital. Selected artists picked an Orbital track, all from the 1991
Mutations_EP
Formation of cancer
mutations that may contribute to the development of cancer. Finally random mistakes in normal DNA replication may result in cancer-causing mutations.
Carcinogenesis
Change in the heritable traits of populations
stripes. However, mutations in the melanocortin 1 receptor (MC1R) disrupt the pattern. The majority of pig breeds carry MC1R mutations disrupting wild-type
Evolution
Process inducing mutations in seeds
M. C.; Shu, Q. Y. (2008). "The role of induced mutations in world food security" (PDF). Induced Plant Mutations in the Genomics Era. Proceedings of
Mutation_breeding
Measure in population genetics
007 relative to the case of no segregating deleterious mutations, if there are 5 new deleterious mutations per replication. However the reference case
Genetic_load
Mutation at a location where intron splicing takes place
subunit. Several genetic diseases may be the result of splice site mutations. For example, mutations that cause the incorrect splicing of β-globin mRNA are
Splice_site_mutation
"pick and choose" mutations which are advantageous and pass them on to an organism's offspring, while discarding deleterious mutations. In asexual lineages
Behavior_mutation
Abnormal number or structure of chromosomes
new mutations that appear in a single generation without prior evidence of mutation in the parental chromosomes. Approximately 7% of de novo mutations are
Chromosome_abnormality
a deletion mutation, or by mutations in nuclear-encoded genes involved in oxidative phosphorylation. Petite mutants can be generated in the laboratory
Petite_mutation
Accumulation of mutations
Somatic evolution is the accumulation of mutations and epimutations in somatic cells (the cells of a body, as opposed to germ plasm and stem cells) during
Somatic_evolution_in_cancer
1973 studio album by Blue Öyster Cult
Tyranny and Mutation (stylized on the cover as THE BLVE ÖYSTER CVLT: TYRANNY AND MVTATION), the second studio album by American rock band Blue Öyster
Tyranny_and_Mutation
Factors causing Parkinson's disease
Some LRRK2 mutations have been linked to dysfunctional protein degradation and clearance. For example, G2019S mutations appear to reduce the ability to
Causes_of_Parkinson's_disease
set of chromosomes, deleterious mutations would be eliminated immediately, and therefore removal of harmful mutations is an unlikely benefit for sexual
Evolution of sexual reproduction
Evolution_of_sexual_reproduction
Allele equilibrium in a population when creation equals elimination by negative selection
are neutral or deleterious; beneficial mutations are relatively rare. The resulting influx of deleterious mutations into a population over time is counteracted
Mutation–selection_balance
Genetic operation used to add population diversity
The following requirements apply to all mutation operators used in an EA: every point in the search space must be reachable by one or more mutations.
Mutation (evolutionary algorithm)
Mutation_(evolutionary_algorithm)
Medical condition
syndrome, which is also associated with dominant mutations in TWIST2. Severe hypertrichosis, especially of the back Skin abnormalities, including hyperlaxity
Barber–Say_syndrome
Unstable mutation in which phenotype severity is linked to copy number
phenomena, in the framework of dynamical genetics, dynamic mutations. Triplet expansion is caused by slippage during DNA replication. Due to the repetitive
Dynamic_mutation
Mutants appearing in fictional stories
The concept of a mutant is a common trope in fiction. The new phenotypes that appear in fictional mutations generally go far beyond what is typically
Mutants_in_fiction
Variant of one theory of evolution
fact that not all mutations are either so deleterious such that they can be ignored, or else neutral. Slightly deleterious mutations are reliably purged
Nearly neutral theory of molecular evolution
Nearly_neutral_theory_of_molecular_evolution
than 50 mutations on its spike protein relative to BA.3, and more than 70 spike mutations relative to the original Wuhan wildtype virus. The subvariant
Variants_of_SARS-CoV-2
Diverse collection of blood-related cancers
sporadic inactivating mutations, in one of the two GATA2 genes. These autosomal dominant mutations reduce the cellular levels of the gene's product, GATA2
Myelodysplastic_syndrome
Genetic process
crossing strains of an organism that each carry mutations through a simple complementation test. When the mutations in question are homozygous and recessive
Complementation_(genetics)
Neuromuscular disease
by genetic mutations that disrupt critical proteins within peripheral nerves. These mutations predominantly affect proteins essential for the structure
Charcot–Marie–Tooth_disease
Dependence of a gene mutation's phenotype on mutations in other genes
genetics in which the effect of a mutation on a trait is dependent on the presence or absence of mutations at different loci (locations on the genome), that
Epistasis
Human genetic disorder
Collins syndrome. TCOF1 gene mutations are the most common cause of the disorder, with POLR1C and POLR1D gene mutations causing an additional 2% of cases
Treacher_Collins_syndrome
Accumulation of harmful mutations
happens because in the absence of recombination, and assuming reverse mutations are rare, offspring bear at least as much mutational load as their parents
Muller's_ratchet
and find mutations in a specific gene. Developed in plants, this technique shares a name with the agricultural preparation of soil. Mutations are caused
List of unusual biological names
List_of_unusual_biological_names
Mitochondrially inherited degeneration of retinal nerve cells
pass on the disease to their offspring. LHON is usually due to one of three pathogenic mitochondrial DNA (mtDNA) point mutations. These mutations are at
Leber's hereditary optic neuropathy
Leber's_hereditary_optic_neuropathy
Method of software testing
Mutation testing (or mutation analysis or program mutation) is used to design new software tests and evaluate the quality of existing software tests.
Mutation_testing
Genetic characteristic of tumorous tissue
that higher TMB levels (≥ 20 mutations/Mb) corresponded to a 58% response rate to ICIs while lower TMB levels (<20 mutations/Mb) reduced response to 20%
Tumor_mutational_burden
Influence of a single gene on multiple phenotypic traits
recombination and mutations, applying it to populations and evolution. This view of pleiotropy, "universal pleiotropy", defined as locus mutations being capable
Pleiotropy
Frequency of mutation of genes
accounting for the emergence of mutations on any given germ line. There are several tests utilized in measuring the chances of mutation frequency and rates
Mutation_frequency
Type of similarity matrix in computational biology
organism. In particular, silent mutations are not point accepted mutations, nor are mutations that are lethal or that are rejected by natural selection in
Point_accepted_mutation
Disorders caused by mitochondrial dysfunction
do—but not all of them; therefore, mutations occur more frequently in mitochondrial DNA than in nuclear DNA (see Mutation rate). This means that mitochondrial
Mitochondrial_disease
Protein-coding gene in humans
Somatic KRAS mutations are found at high rates in leukemias, colorectal cancer, pancreatic cancer and lung cancer. The impact of KRAS mutations is heavily
KRAS
Free web-based application to evaluate DNA variants for their disease-causing potential
disease-causing mutation and gives detailed information about the mutation. Importantly, the predictions of clinical effects of mutations suffer from a
MutationTaster
American superhero television series
Turtles: The Next Mutation is an American television series produced by Saban Entertainment. It is the only live-action television series in the Teenage
Ninja Turtles: The Next Mutation
Ninja_Turtles:_The_Next_Mutation
Mammalian protein found in Homo sapiens
(7): 3346–53. doi:10.1128/JVI.01927-06. PMC 1866021. PMID 17229697. Interferon-γ Receptor-1 and 2 Mutations Interferon gamma receptor (IFNGR1) family
Interferon-gamma_receptor
Card game
of either positive or negative mutation. As a result of natural selection that plays out on the game – positive mutations remain more often than negative
Evolution:_Random_Mutations
Mutation affecting the colour of a budgerigar
The violet budgerigar mutation is one of approximately 30 mutations affecting the colour of budgerigars. It is one of the constituent mutations of the
Violet_budgerigar_mutation
like all living organisms, occasionally have mutations that affect their body type. Sometimes, these mutations are striking enough that humans select for
List of cat body-type mutations
List_of_cat_body-type_mutations
Variant of genes who alter their functions during temperature changes
the protein is unstable and ceases to function properly. These mutations are usually recessive in diploid organisms. Temperature -sensitive mutations
Temperature-sensitive_mutant
Genetic mutation in animals, producing curled fur or feathers
individual hairs. The rexed coats are unusual but occur (and have been preserved) in cats, rats, rabbits, horses, and dogs. The mutations, infrequent and
Rex_mutation
Topics referred to by the same term
U-mutation, or u-umlaut, can refer to various processes that occurred in the history of some Germanic languages: Old Norse u-umlaut, allophones of non-rounded
U-mutation
that the effect of natural selection is minimized, with the aim of quantitatively estimating the rates at which spontaneous mutations (mutations not caused
Mutation accumulation experiments
Mutation_accumulation_experiments
Part of commercial winemaking and viticulture
While there may be slight mutations to differentiate the various clones, all clones are considered genetically part of the same variety (i.e. Sangiovese
Propagation_of_grapevines
colour mutations occur in captivity as well as in the wild. This has been demonstrated when captive-bred budgerigars have developed mutations that had
Budgerigar_colour_genetics
Topics referred to by the same term
Virus mutation is mutation of viruses and may refer to: The feature of viruses to cause mutation in the human genome The feature of viruses to perform
Virus_mutation
Protein found in humans
inactivating mutations, colon cancers commonly carry activating mutations in beta catenin or inactivating mutations in RNF43. Mutations in APC can be
Adenomatous_polyposis_coli
Tumor or other abnormal growth of tissue
all areas of the cancer), 59 mutations shared by some (but not all areas), and 29 "private" mutations only present in one of the areas of the cancer. Various
Neoplasm
Species of fruit fly
aging. It is caused by mutations in the gene WRN that encodes a protein with essential roles in repair of DNA damage. Mutations in the D. melanogaster homolog
Drosophila_melanogaster
Theory of aging
consistently eliminate these mutations. Medawar posited that over time these mutations would accumulate due to genetic drift and lead to the evolution of what is
Mutation_accumulation_theory
Physical or chemical agent that increases the rate of genetic mutation
leading to an altered base pair, a mutation. However, mutations and DNA damages differ in a fundamental way: mutations can, in principle, be replicated
Mutagen
Mammalian protein found in humans
activation. These are typically recessive loss-of-function mutations. By contrast, mutations in the OD can exert dominant negative effects by forming inactive
P53
Mammalian protein found in humans
include two different mutations, and homozygous, meaning they involve the same mutation. Delta F508 is the most common mutation, accounting for more than
Cystic fibrosis transmembrane conductance regulator
Cystic_fibrosis_transmembrane_conductance_regulator
Variety of cockatiel
The lutino cockatiel is one of the most popular mutations of cockatiel, with white to light-yellow feathers and orange/red cheek patches. The "normal
Lutino_cockatiel
inherit deleterious mitochondrial genome (mtDNA) mutations from their mother, while those mutations are beneficial, neutral or less deleterious to females
Mother's_curse
Marvel Comics superhero
possible physical mutations and in many cases grants some form of superhuman ability. Nightcrawler possesses superhuman agility, the ability to teleport
Nightcrawler_(character)
Theory of evolution by changes at the molecular level
emphasized the importance of nearly neutral mutations, in particularly slightly deleterious mutations. The Nearly neutral theory stems from the prediction
Neutral theory of molecular evolution
Neutral_theory_of_molecular_evolution
2021 British film
The Mutation is a 2021 British horror film directed by Scott Jeffrey, starring Ricardo Freitas, Amanda-Jade Tyler, Abi Casson Thompson, James Robertson
The_Mutation_(film)
Genetic disorder of the skull
abnormalities of the hands and feet, such as wide and deviated thumbs and big toes. Pfeiffer syndrome is caused by mutations in the fibroblast growth
Pfeiffer_syndrome
Gene known for its role in breast cancer
mutation in BRCA1 or BRCA2. Similarly, BRCA1 mutations are only seen in about 18% of ovarian cancers (13% germline mutations and 5% somatic mutations)
BRCA1
Medical condition
mutations in one of the two parental GATA2 genes. Because the gene is haploinsufficient, mutations that cause a reduction in cellular levels of the gene's
GATA2_deficiency
Scientific study
to 20 beneficial mutations achieved fixation in each population, with fewer than 100 total point mutations (including neutral mutations) reaching fixation
E. coli long-term evolution experiment
E._coli_long-term_evolution_experiment
Medical condition for inability to feel pain
genetic conditions. CIP is caused by genetic mutations that affect the development or function of nociceptors, the sensory neurons responsible for recognizing
Congenital insensitivity to pain
Congenital_insensitivity_to_pain
THE MUTATIONS
THE MUTATIONS
Male
Native American
Native American Navajo name TSE means "rock."
Surname or Lastname
English (mainly East Anglia)
English (mainly East Anglia) : topographic name for someone who lived by a common pasture, Middle English tye (Old English tēag).North German : from a short form, Tide, of the personal name Dietrich.
Girl/Female
Hindu
Gift of God
Female
Vietnamese
Vietnamese name THI means "poem."
Male
English
English surname transferred to forename use, derived from the Middle English word tye, TYE means "pasture."
Boy/Male
Arthurian Legend American Hebrew Spanish
Arthur's brother.
Girl/Female
Greek American
Goddess; godly. Also as abbreviation of names like Althea and Dorothea. The mythological Thea was...
Girl/Female
Finnish, German, Greek
Gift of God
Female
Vietnamese
Vietnamese name THU means "autumn."
Boy/Male
English
From the enclosure.
Female
Greek
 Short form of Greek and Latin Dorothea, THEA means "gift of God." Compare with another form of Thea.
Surname or Lastname
English (Yorkshire)
English (Yorkshire) : variant of Tye.
Female
German
Pet form of German Kätharina, KÄTHE means "pure."
Girl/Female
Greek
Untamed.
Surname or Lastname
English
English : status name from Middle English thewe ‘thrall’, ‘slave’ (Old English þēow).
Boy/Male
Native American
Rock.
Male
English
Short form of English Theodore, THEO means "gift of God," and other names beginning with Theo-.
Boy/Male
Greek American German
God given.
Female
English
 Pet form of English Theodora, THEA means "gift of God." Compare with another form of Thea.
Girl/Female
Hindu, Indian, Malayalam, Modern, Tamil
Nil
THE MUTATIONS
THE MUTATIONS
Male
Scandinavian
Contracted form of Scandinavian Ingemar, INGMAR means "Ing-famous."
Male
English
Latin form of Greek Lysandros, LYSANDER means "freer; liberator." This was the name of the main character in Shakespeare's A Midsummer Night's Dream. In use by the English.
Boy/Male
Arabic, Muslim
Name of a Prophet
Surname or Lastname
English
English : variant spelling of Hinckley.
Female
English
Early form of Roman Latin Juliana, JILLIAN means "descended from Jupiter (Jove)."
Boy/Male
Irish
Red-haired.
Boy/Male
Tamil
Victory
Boy/Male
Arabic, Muslim, Swahili
Beneficent; Charitable
Boy/Male
Assamese, Celebrity, Gujarati, Hindu, Indian, Jain, Kannada, Malayalam, Marathi, Oriya, Punjabi, Sanskrit, Sikh, Tamil, Telugu, Traditional
Sky; Lord of Day; Uncountable; Space
Boy/Male
Biblical
Strength of the Lord.
THE MUTATIONS
THE MUTATIONS
THE MUTATIONS
THE MUTATIONS
THE MUTATIONS
n.
Anything, or any part, corresponding to the toe of the foot; as, the toe of a boot; the toe of a skate.
v. i.
See Thee.
v. t.
To touch or reach with the toes; to come fully up to; as, to toe the mark.
adv.
By that; by how much; by so much; on that account; -- used before comparatives; as, the longer we continue in sin, the more difficult it is to reform.
n.
One of the terminal members, or digits, of the foot of a man or an animal.
v. t.
See Tie, the proper orthography.
n.
The fore part of the hoof or foot of an animal.
obj.
This or that female; the woman understood or referred to; the animal of the female sex, or object personified as feminine, which was spoken of.
obj.
The plural of he, she, or it. They is never used adjectively, but always as a pronoun proper, and sometimes refers to persons without an antecedent expressed.
pron.
The objective case of they. See They.
v. t.
A line, usually straight, drawn across the stems of notes, or a curved line written over or under the notes, signifying that they are to be slurred, or closely united in the performance, or that two notes of the same pitch are to be sounded as one; a bind; a ligature.
n.
The parson bird.
def. art.
The.
n.
A chain or rope, one end of which passes through the mast, and is made fast to the center of a yard; the other end is attached to a tackle, by means of which the yard is hoisted or lowered.
n.
The nodule of earth from which the ball is struck in golf.
pron.
The objective case of thou. See Thou.
pron.
Of thee, or belonging to thee; the more common form of thine, possessive case of thou; -- used always attributively, and chiefly in the solemn or grave style, and in poetry. Thine is used in the predicate; as, the knife is thine. See Thine.
n.
The point of intersection of a vertical line through the center of gravity of the fluid displaced by a floating body which is tipped through a small angle from its position of equilibrium, and the inclined line which was vertical through the center of gravity of the body when in equilibrium.
definite article.
A word placed before nouns to limit or individualize their meaning.