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2002 book by psychologist David Moore
The Dependent Gene: The Fallacy of "Nature vs. Nurture" is a book by developmental psychologist David S. Moore, originally published in 2002 by Times
The_Dependent_Gene
Long-standing debate in biology and society
Appleton. p. 9. Nature versus nurture galton. Moore, David (2003). The Dependent Gene: The Fallacy of "Nature Vs. Nurture". Henry Holt and Company. ISBN 9780805072808
Nature_versus_nurture
Synthetic viral vector
gene therapy. Naturally occurring satellite viruses are also helper virus dependent, and can sometimes be modified to become viral vectors. Since the
Helper_dependent_virus
Neuroplasticity that arise from use of cognitive functions
Activity-dependent plasticity is a form of functional and structural neuroplasticity that arises from the use of cognitive functions and personal experience
Activity-dependent_plasticity
American neuroscientist (born 1954)
depolarize neurons, the subsequent downstream signaling cascade that culminates in gene expression, and the pattern of experience-dependent gene expression in
Michael_E._Greenberg
Protein complex
cycle-dependent gene expression. The complex is evolutionarily conserved, although some of its components vary from species to species. In humans, the key
DREAM_complex
Chinese neuroscientist
"Scientists edit mice genes to tackle autism". China Daily. Retrieved 2026-08-03. Qiu, Zilong; Cheng, Ju (2010). "The role of calcium-dependent gene expression in
Qiu_Zilong
Protein found in humans
by the CAMK2A gene. The product of the CAMK2A gene is an enzyme that belongs to the serine/threonine-specific protein kinase family, as well as the
Calcium/calmodulin-dependent protein kinase type II subunit alpha
Calcium/calmodulin-dependent_protein_kinase_type_II_subunit_alpha
Protein
induction of E2F-dependent genes. Studies have also shown that LANA-1 can transactivate the promoter of the reverse transcriptase subunit of the human telomerase
LANA
Protein found in humans
Insulin dependent diabetes mellitus 3 is a protein that in humans is encoded by the IDDM3 gene. "Human PubMed Reference:". National Center for Biotechnology
Insulin dependent diabetes mellitus 3
Insulin_dependent_diabetes_mellitus_3
Study of inheritance as it occurs in human beings
in: Susan M Schneider (Spring 2007). "The Tangled Tale of Genes and Environment: Moore's The Dependent Gene: The Fallacy of "nature VS. Nurture"". Behav
Human_genetics
Protein in Candida albicans
calcineurin dependent-genes in Candida albicans. The cytoplasmic protein Crz1 is dephosphorylated by the calcineurin and is then targeted to the nucleus. The nuclear
CRZ1
Protein in homo sapiens
FAD-dependent oxidoreductase domain-containing protein 2 is a protein in humans encoded by the FOXRED2 gene. GRCh38: Ensembl release 89: ENSG00000100350
FAD-dependent oxidoreductase domain-containing protein 2
FAD-dependent_oxidoreductase_domain-containing_protein_2
Protein-coding gene in humans
CDKN2A, also known as cyclin-dependent kinase inhibitor 2A, is a gene which in humans is located at chromosome 9, band p21.3. It is ubiquitously expressed
CDKN2A
Protein-coding gene in the species Homo sapiens
NADP-dependent malic enzyme is a protein that in humans is encoded by the ME1 gene. This gene encodes a cytosolic, NADP-dependent enzyme that generates
ME1_(gene)
Protein-coding gene in the species Homo sapiens
(Jun 1999). "Ca2(+)-dependent interaction of N-copine, a member of the two C2 domain protein family, with OS-9, the product of a gene frequently amplified
OS9_(gene)
Gene therapy
autotemcel, sold under the brand name Casgevy, is a gene therapy used for the treatment of sickle cell disease and transfusion-dependent beta thalassemia.
Exagamglogene_autotemcel
Protein-coding gene in the species Homo sapiens
Cyclin-dependent kinase inhibitor 1C (p57, Kip2), also known as CDKN1C, is a protein which in humans is encoded by the CDKN1C imprinted gene. Cyclin-dependent
Cyclin-dependent kinase inhibitor 1C
Cyclin-dependent_kinase_inhibitor_1C
Human protein
Cyclin-dependent kinase 4 (CDK4), also known as cell division protein kinase 4, is an enzyme that is encoded by the CDK4 gene in humans. CDK4 is a member
Cyclin-dependent_kinase_4
Protein-coding gene in humans
Voltage-dependent calcium channel subunit alpha-2/delta-1 is a protein that in humans is encoded by the CACNA2D1 gene. The CACNA2D1 gene is located on
CACNA2D1
Protein found in humans
Cyclin-dependent kinase 2, also known as cell division protein kinase 2, or Cdk2, is an enzyme that in humans is encoded by the CDK2 gene. The protein
Cyclin-dependent_kinase_2
Protein-coding gene in humans
Voltage-dependent L-type calcium channel subunit alpha-1C (also known as Cav1.2) is a protein that in humans is encoded by the CACNA1C gene. Cav1.2 is
CACNA1C
Protein-coding gene in humans
Calcium/calmodulin-dependent protein kinase type II beta chain is an enzyme that in humans is encoded by the CAMK2B gene. The enzyme belongs to the serine/threonine
CAMK2B
Protein-coding gene in humans
Activity-dependent neuroprotector homeobox is a protein that in humans is encoded by the ADNP gene. Vasoactive intestinal peptide is a neuroprotective
ADNP_(gene)
Protein-coding gene in the species Homo sapiens
In the field of biochemistry, PDPK1 refers to the protein 3-phosphoinositide-dependent protein kinase-1, an enzyme which is encoded by the PDPK1 gene in
Phosphoinositide-dependent kinase-1
Phosphoinositide-dependent_kinase-1
Protein found in humans
Calcium/calmodulin dependent protein kinase II inhibitor 1 is a protein that in humans is encoded by the CAMK2N1 gene. GRCh38: Ensembl release 89: ENSG00000162545
Calcium/calmodulin dependent protein kinase II inhibitor 1
Calcium/calmodulin_dependent_protein_kinase_II_inhibitor_1
Biological hypothesis
flexibly to internal and external inputs. One example is condition-dependent gene expression, but regulatory systems also rely on physical properties
Constructive development (biology)
Constructive_development_(biology)
Protein-coding gene in the species Homo sapiens
Cytokine dependent hematopoietic cell linker is a protein that in humans is encoded by the CLNK gene. CLNK is a member of the SLP76 family of adaptors
Cytokine dependent hematopoietic cell linker
Cytokine_dependent_hematopoietic_cell_linker
Protein-coding gene in humans
NADP(+)-dependent isozyme is a homodimer. The protein encoded by the IDH2 gene is the NADP(+)-dependent isocitrate dehydrogenase found in the mitochondria
IDH2
Protein-coding gene in the species Homo sapiens
NAD-dependent malic enzyme, mitochondrial is a protein that in humans is encoded by the ME2 gene. This gene encodes a mitochondrial NAD-dependent malic
ME2_(gene)
Protein-coding gene in the species Homo sapiens
Tremblay J, Lacroix A (2003). "Analysis of the putative promoter region of the GIP receptor gene (GIPR) in GIP-dependent Cushing's syndrome (CS)". Endocr. Res
Gastric inhibitory polypeptide receptor
Gastric_inhibitory_polypeptide_receptor
Class of enzymes
known structure is the E. coli NADP-dependent IDH, which has only two subunits and a 13% identity and 29% similarity based on the amino acid sequences
Isocitrate_dehydrogenase
Dicarboxylic acid
succinate will mimic the hypoxia state by suppressing PHDs, therefore stabilizing HIF1α and inducing the transcription of HIF1-dependent genes even under normal
Succinic_acid
Protein-coding gene in the species Homo sapiens
Androgen-dependent TFPI-regulating protein is a protein in humans that is encoded by the ADTRP gene. GRCh38: Ensembl release 89: ENSG00000111863 – Ensembl
Androgen-dependent TFPI-regulating protein
Androgen-dependent_TFPI-regulating_protein
Non-coding RNA
unknown until recently. In the early 2000s, scientists found out the function of 6S RNA to be as a regulator of sigma 70-dependent gene transcription. All bacterial
6S_/_SsrS_RNA
Number of gene copies in a genome
the amount of gene product produced in a cell is more commonly dependent on regulation of gene expression. The normal gene dosage is dependent on the
Gene_dosage
Mammalian protein found in humans
cyclin-dependent kinase inhibitor 2A, CDKN2A, multiple tumor suppressor 1 and numerous other synonyms), is a protein that slows cell division by slowing the
P16
Process of copying a segment of DNA into RNA
Transcription is the process of duplicating a segment of DNA into RNA for the purpose of gene expression. Some segments of DNA are transcribed into RNA
Transcription_(biology)
Protein-coding gene in the species Homo sapiens
alpha-ketoglutarate-dependent dioxygenase is a protein that in humans is encoded by the ALKBH3 gene. The Escherichia coli AlkB protein protects against the cytotoxicity
AlkB homolog 3, alpha-ketoglutarate-dependent dioxygenase
AlkB_homolog_3,_alpha-ketoglutarate-dependent_dioxygenase
Protein-coding gene in the species Homo sapiens
ATP-dependent chromatin remodeler SMARCA4 is a protein that in humans is encoded by the SMARCA4 gene. The protein encoded by this gene is a member of the
SMARCA4
Way to propagate genes throughout a population
population by altering the probability that a specific allele will be transmitted to offspring (instead of the Mendelian 50% probability). Gene drives can arise
Gene_drive
Protein-coding gene in humans
AMP-dependent transcription factor ATF-3 is a protein that, in humans, is encoded by the ATF3 gene. Activating transcription factor 3 is a member of the mammalian
ATF3
Chromosome that differs from an ordinary autosome in form, size, and behavior
or idiochromosomes) are chromosomes that carry the genes that determine the sex of an individual. The human sex chromosomes are a typical pair of mammal
Sex_chromosome
Environmental sex determination by temperature during development
Temperature-dependent sex determination (TSD) is a type of environmental sex determination in which the temperatures experienced during embryonic/larval
Temperature-dependent sex determination
Temperature-dependent_sex_determination
Research paradigm in behavioural genetics
determinism, is the belief that human behaviour is directly controlled by an individual's genes or some component of their physiology, generally at the expense
Biological_determinism
Protein-coding gene in the species Homo sapiens
cAMP-dependent protein kinase type I-alpha regulatory subunit is an enzyme that in humans is encoded by the PRKAR1A gene. cAMP is a signaling molecule
PRKAR1A
Protein kinase gene
CDK12 cyclin-dependent kinase 12 is a protein kinase that in humans is encoded by the CDK12 gene. This enzyme is a member of cyclin-dependent kinase protein
CDK12
Protein-coding gene in the species Homo sapiens
W; Haegeman G; Beyaert R (June 1999). "The zinc finger protein A20 inhibits TNF-induced NF-kappaB-dependent gene expression by interfering with an RIP-
TNFAIP3
Protein-coding gene in the species Homo sapiens
Cyclin-dependent kinase 9 or CDK9 is a cyclin-dependent kinase associated with P-TEFb. The protein encoded by this gene is a member of the cyclin-dependent kinase
Cyclin-dependent_kinase_9
Study of DNA modifications that do not change its sequence
Epigenetics is the study of changes in gene expression that occur without altering the DNA sequence. The Greek prefix epi- (ἐπι- "over, outside of, around")
Epigenetics
Type of enzyme
(August 1988). "Sequence of the lon gene in Escherichia coli. A heat-shock gene which encodes the ATP-dependent protease La". The Journal of Biological Chemistry
Endopeptidase_La
Protein
is encoded by the CDKN1A gene located on chromosome 6 (6p21.2) in humans. p21 is a potent cyclin-dependent kinase inhibitor (CKI). The p21 (CIP1/WAF1)
P21
Protein-coding gene in the species Homo sapiens
Cyclin dependent kinase like 1 is a protein that in humans is encoded by the CDKL1 gene. This gene product is a member of a large family of CDC2-related
Cyclin dependent kinase like 1
Cyclin_dependent_kinase_like_1
Protein-coding gene in the species Homo sapiens
that in humans is encoded by the ARC gene. The gene is believed to derive from a retrotransposon. The protein is found in the neurons of tetrapods and other
Activity-regulated cytoskeleton-associated protein
Activity-regulated_cytoskeleton-associated_protein
Conversion of mechanical stimulus of a cell into electrochemical activity
"Mechanical Compression of Cartilage Explants Induces Multiple Time-dependent Gene Expression Patterns and Involves Intracellular Calcium and Cyclic AMP"
Mechanotransduction
Protein-coding gene in humans
Cyclin-dependent kinase 5 activator 2 is an enzyme that in humans is encoded by the CDK5R2 gene. The protein encoded by this gene is a neuron-specific
CDK5R2
Protein-coding gene in the species Homo sapiens
cAMP-dependent protein kinase inhibitor alpha is a protein that in humans is encoded by the PKIA gene. The protein encoded by this gene is a member of the
PKIA
Protein-coding gene in the species Homo sapiens
the ARGLU1 gene located at 13q33.3. The protein product of this gene has been proposed as a MED1-interacting protein required for estrogen-dependent gene
ARGLU1
Enzyme found in humans
enhancer factor-2 (MEF2) proteins, resulting in repression of MEF2-dependent genes. This gene is thought to be associated with colon cancer. Two transcript
Histone_deacetylase_5
Protein-coding gene in humans
Calcium/calmodulin-dependent protein kinase kinase 1 is an enzyme that in humans is encoded by the CAMKK1 gene. The product of this gene belongs to the serine/threonine
CAMKK1
Class of enzymes
applications). Purified DNA ligase is used in gene cloning to join DNA molecules together to form recombinant DNA. The mechanism of DNA ligase is to form two
DNA_ligase
Protein-coding gene in humans
Cyclin-dependent kinase 5 activator 1 is an enzyme that in humans is encoded by the CDK5R1 gene. The protein encoded by this gene (p35) is a neuron-specific
CDK5R1
Protein-coding gene in humans
Calcium/calmodulin-dependent protein kinase kinase 2 is an enzyme that in humans is encoded by the CAMKK2 gene. The product of this gene belongs to the serine/threonine-specific
CAMKK2
Biological gene-regulation phenomenon
(Ago)-dependent gene regulation phenomenon in which promoter-targeted short double-stranded RNAs (dsRNAs) induce target gene expression at the
RNA_activation
Protein-coding gene in the species Homo sapiens
Silvennoinen O, Rämet M (March 2012). "Not4 enhances JAK/STAT pathway-dependent gene expression in Drosophila and in human cells". FASEB Journal. 26 (3):
CNOT4
Biologically active form of vitamin B12
"An Old Cofactor in a New Light: Adenosylcobalamin in Light-Dependent Gene Regulation". The FASEB Journal. 29. doi:10.1096/fasebj.29.1_supplement.573.25
Adenosylcobalamin
Protein found in humans
encoded by the CDK6 gene. It is regulated by cyclins, more specifically by cyclin D proteins and cyclin-dependent kinase inhibitor proteins. The protein
Cyclin-dependent_kinase_6
Protein-coding gene in humans
Cyclic AMP-dependent transcription factor ATF-1 is a protein that in humans is encoded by the ATF1 gene. This gene encodes an activating transcription
ATF1
Protein-coding gene in humans
Calcium/calmodulin-dependent protein kinase type IV is an enzyme that in humans is encoded by the CAMK4 gene. The product of this gene belongs to the serine/threonine
CAMK4
Mammalian protein found in Homo sapiens
Sodium-dependent multivitamin transporter is a protein that in humans is encoded by the SLC5A6 gene. The SMVT is a transporter for pantothenic acid (vitamin
Sodium-dependent multivitamin transporter
Sodium-dependent_multivitamin_transporter
Protein-coding gene in humans
Voltage-dependent L-type calcium channel subunit beta-4 is a protein that in humans is encoded by the CACNB4 gene. This gene encodes a member of the beta
CACNB4
Protein found in humans
in humans is encoded by the CCND1 gene. The CCND1 gene encodes the cyclin D1 protein. The human CCND1 gene is located on the long arm of chromosome 11
Cyclin_D1
Method of determining sex
reptiles, and various other animals, in which the heterogametic sex is female. A temperature-dependent sex determination system is found in some reptiles
XY_sex-determination_system
Protein-coding gene in the species Homo sapiens
regulates gene expression. The enzymatic activity of Sirt6, as well as of the other members of the sirtuins family, is dependent upon the binding of the cofactor
Sirtuin_6
Insulin-dependent (type I) diabetes mellitus
MHC HLA gene (IDDM1) and the insulin gene INS (IDDM2) are the major genetic candidates in the development of insulin-dependent (type I) diabetes mellitus(IDDM)
IDDM11
Protein-coding gene in the species Homo sapiens
Transcription-Dependent Manner". Mol Cell Biol. 23 (14): 4859–69. doi:10.1128/MCB.23.14.4859-4869.2003. PMC 162212. PMID 12832472. "Entrez Gene: HEXIM1 hexamethylene
HEXIM1
Topics referred to by the same term
Z-gene or Z gene may refer to: lacZ, a gene in the lac operon Beta-galactosidase, the type of protein encoded by lacZ Protein Z, a vitamin K-dependent glycoprotein
Z-gene
Enzyme that synthesizes RNA from DNA during Transcription
DNA-directed/dependent RNA polymerase (DdRP), is an enzyme that catalyzes the chemical reactions that synthesize RNA from a DNA template strand. Along with the enzyme
RNA_polymerase
Conversion of a gene's sequence into a mature gene product or products
Gene expression is the process by which the information contained within a gene is used to produce a functional gene product, such as a protein or a functional
Gene_expression
Protein-coding gene in the species Homo sapiens
addition, the product of this gene binds to the product of the PDCD6 gene, a protein required for apoptosis, in a calcium-dependent manner. This gene product
PDCD6IP
Mammalian protein found in Homo sapiens
Ligand dependent nuclear receptor corepressor like is a protein that in humans is encoded by the LCORL gene. This gene encodes a transcription factor
LCORL
Biological process
Synthesis Dependent Strand Annealing (SDSA), there is information exchange but not physical exchange. Gene conversion will occur during SDSA if the two DNA
Gene_conversion
Mammalian protein found in humans
(March 1998). "BRCA1 regulates p53-dependent gene expression". Proceedings of the National Academy of Sciences of the United States of America. 95 (5):
P53
Protein-coding gene in the species Homo sapiens
Sodium-dependent phosphate transport protein 2B (NaPi2b) is a protein that in humans is encoded by the SLC34A2 gene. Sodium-dependent phosphate transport
Sodium-dependent phosphate transport protein 2B
Sodium-dependent_phosphate_transport_protein_2B
Model of DNA repair in biology
(September 1997). "Cell cycle-dependent protein expression of mammalian homologs of yeast DNA double-strand break repair genes Rad51 and Rad52". Mutation
Double-strand break repair model
Double-strand_break_repair_model
Mammalian protein found in humans
The serotonin transporter (SERT or 5-HTT), also known as the sodium-dependent serotonin transporter and solute carrier family 6 member 4, is a protein
Serotonin_transporter
Protein-coding gene in the species Homo sapiens
is an enzyme that in humans is encoded by the SKP1 gene. This gene encodes a protein that is a member of the SCF ubiquitin ligase protein complex. It binds
S-phase kinase-associated protein 1
S-phase_kinase-associated_protein_1
Protein-coding gene in humans
Cyclin-dependent kinase inhibitor 1B (p27Kip1) is an enzyme inhibitor that in humans is encoded by the CDKN1B gene. It encodes a protein which belongs
CDKN1B
Human protein and coding gene
2003). "The ATP-dependent Lon protease of Mus musculus is a DNA-binding protein that is functionally conserved between yeast and mammals". Gene. 306: 45–55
LONP1
Swiss-American biotechnology company
Switzerland. The company does business as CRISPR Therapeutics, Inc. in the United States. It was one of the first companies formed to utilize the CRISPR gene editing
CRISPR_Therapeutics
Protein-coding gene in the species Homo sapiens
cAMP-dependent protein kinase type II-alpha regulatory subunit is an enzyme that in humans is encoded by the PRKAR2A gene. cAMP is a signaling molecule
PRKAR2A
expression. Enhanced CREB-dependent gene expression increases the excitability of neurons in the basal amygdala and primes the consolidation of contextual
CREB_in_cognition
Enzyme that synthesizes RNA from an RNA template
RNA-dependent RNA polymerase (RdRp) or RNA replicase is an enzyme that catalyzes the replication of RNA from an RNA template. Specifically, it catalyzes
RNA-dependent_RNA_polymerase
Protein-coding gene in the species Homo sapiens
encoded by the FBXO11 gene. This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box
FBXO11
Protein-coding gene in humans
Calcium/calmodulin-dependent protein kinase ID is a protein in humans that is encoded by the CAMK1D gene on chromosome 10 (locus 10p13). This gene encodes a member
CAMK1D
Protein found in humans
voltage-dependent, T type, alpha 1H subunit, also known as CACNA1H, is a protein which in humans is encoded by the CACNA1H gene. This gene encodes Cav3
Calcium channel, voltage-dependent, T type, alpha 1H subunit
Calcium_channel,_voltage-dependent,_T_type,_alpha_1H_subunit
Protein-coding gene in the species Homo sapiens
a protein that in humans is encoded by the S100G gene. This gene encodes calbindin D9K, a vitamin D-dependent calcium-binding protein. This cytosolic
S100G
Protein-coding gene in the species Homo sapiens
cAMP-dependent protein kinase type II-beta regulatory subunit is an enzyme that in humans is encoded by the PRKAR2B gene. cAMP is a signaling molecule
PRKAR2B
Protein found in humans
PMID 23395801. "Entrez Gene: TBK1 TANK-binding kinase 1". Louis C, Burns C, Wicks I (2018-03-06). "TANK-Binding Kinase 1-Dependent Responses in Health and
TANK-binding_kinase_1
Protein-coding gene in humans
Cyclin-dependent kinase 4 inhibitor D is an enzyme that in humans is encoded by the CDKN2D gene. The protein encoded by this gene is a member of the INK4
CDKN2D
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