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Stem cell markers are genes and their protein products used by scientists to isolate and identify stem cells. Stem cells can also be identified by functional
Stem_cell_marker
Unspecialized biological cell that can become specialized
multicellular organisms, stem cells are undifferentiated or partially differentiated cells that can change into various types of cells and proliferate indefinitely
Stem_cell
Multipotent adult stem cells present in multiple tissues
Mesenchymal stem cells (MSCs), also known as mesenchymal stromal cells or medicinal signaling cells, are multipotent stromal cells that can differentiate
Mesenchymal_stem_cell
STRO-1 (Stro-1 in mouse, rat, etc.) is a gene for a protein marker of mesenchymal stem cells (MSC). Molecular mass of Stro-1 is 75kD. The name STRO-1 is
STRO-1
stem cell marker genes, including their name and known function. In the adult intestine, the crypts of Lieberkühn are the niche for epithelial stem cells
List of intestinal stem cell marker genes
List_of_intestinal_stem_cell_marker_genes
Stem cells that give rise to other blood cells
Hematopoietic stem cells (HSCs) are the stem cells that give rise to other blood cells. This process is called haematopoiesis. In vertebrates, the first
Hematopoietic_stem_cell
Pharmaceutical compound
Characteristics of limbal stem cells include a slow turnover rate, high proliferative potential, clonogenicity, expression of stem cell markers, as well as the
Limbal_stem_cell
Cancer cells with features of normal cells
Cancer stem cells (CSCs) are cancer cells (found within tumors or hematological cancers) that possess characteristics associated with normal stem cells, specifically
Cancer_stem_cell
Pluripotent stem cell generated directly from a somatic cell
pluripotent stem cells (also known as iPS cells or iPSCs) are a type of pluripotent stem cell that can be generated directly from a somatic cell. The iPSC
Induced_pluripotent_stem_cell
Aggressive type of brain cancer
can also be used as a cancer stem cell marker in a subset of glioblastoma tumour cells. Glioblastoma cancer stem cells appear to exhibit enhanced resistance
Glioblastoma
Ethical concerns about embryonic stem cell research and medical use
stem cells. Not all stem cell research involves human embryos. For example, adult stem cells, amniotic stem cells, and induced pluripotent stem cells
Stem_cell_controversy
Endogenous tag expressed in different cells along neurogenesis and differentiated cells
A neuronal lineage marker is an endogenous tag that is expressed in different cells along neurogenesis and differentiated cells such as neurons. It allows
Neuronal_lineage_marker
Endogenous non-cancerous pluripotent stem cell
A Muse cell (Multi-lineage differentiating stress-enduring cell) is an endogenous non-cancerous pluripotent stem cell. They reside in the connective tissue
Muse_cell
Protein-coding gene in the species Homo sapiens
and CD6+ cells during intrathymic T cell development.[citation needed] Recently, CD166 has also been used as a potential cancer stem cell marker.[citation
ALCAM
Precursor cells of neurons and glia during embryonic development
Neural stem cells (NSCs) are self-renewing, multipotent cells that firstly generate the radial glial progenitor cells that generate the neurons and glia
Neural_stem_cell
Specific location in the body containing stem cells
Stem-cell niche refers to a microenvironment, within the specific anatomic location where stem cells are found, which interacts with stem cells to regulate
Stem-cell_niche
been reported to be a source of mesenchymal stem cells termed (CLMCs). These cells express MSC specific markers such as NT5E (cluster of differentiation73)
Cord_lining
Stem cells
of stem cell differentiation are cell fate and cell state. Cell fate is the likelihood a cell will differentiate into a particular type of cell. Cell state
Stem_cell_proteomics
Spermatogonium that does not differentiate into a spermatocyte
A spermatogonial stem cell (SSC), also known as a type A spermatogonium, is a spermatogonium that does not differentiate into a spermatocyte, a precursor
Spermatogonial_stem_cell
Transformation of a stem cell to a more specialized cell
specification, is the process in which a stem cell changes from one type to a differentiated one. Usually, the cell changes to a more specialized type. Differentiation
Cellular_differentiation
Mammalian protein found in Homo sapiens
self-renewal of undifferentiated embryonic stem cells. As such, it is frequently used as a marker for undifferentiated cells. Oct-4 expression must be closely
Oct-4
Reoccurrence of cancer
Farah, Camile S. (2013-03-03). "Cancer Stem Cell Markers in Head and Neck Squamous Cell Carcinoma". Stem Cells International. 2013 e319489. doi:10.1155/2013/319489
Recurrent_cancer
Cell that differentiates into one or a few cell types
A progenitor cell is a biological cell that can differentiate into a specific cell type. Stem cells and progenitor cells have this ability in common.
Progenitor_cell
Artificial miniature brain like organ
neural progenitor cells and stem cells are differentiating into specific neural tissues, several gene markers can be tested. Two markers that are present
Cerebral_organoid
Transmembrane glycoprotein
Budhu A, Forgues M, Wang XW (November 2007). "Activation of hepatic stem cell marker EpCAM by Wnt-beta-catenin signaling in hepatocellular carcinoma". Cancer
Epithelial cell adhesion molecule
Epithelial_cell_adhesion_molecule
Medical procedure to replace blood or immune stem cells
Hematopoietic stem-cell transplantation (HSCT) is the transplantation of multipotent hematopoietic stem cells, usually derived from bone marrow, peripheral
Hematopoietic stem cell transplantation
Hematopoietic_stem_cell_transplantation
Stem cell in bone marrow that gives rise to endothelial cells
Endothelial stem cells (ESCs) are one of three types of stem cells found in bone marrow. They are multipotent, which describes the ability to give rise
Endothelial_stem_cell
Protein-coding gene in the species Homo sapiens
signaling pathway mediator. LGR6 also acts as an epithelial stem cell marker in squamous cell carcinoma in mice in vivo. This gene encodes a member of the
LGR6
Mixture of stem cells that can be obtained from amniotic fluid
Amniotic stem cells are the mixture of stem cells that can be obtained from the amniotic fluid as well as the amniotic membrane. They can develop into
Amniotic_stem_cells
Protein-coding gene in humans
well-established stem cell markers in certain types of tissue, wholly due to the fact that they are highly enriched in truly, multipotent stem cells compared
LGR5
Classification in immunology
used as cell markers in immunophenotyping, allowing cells to be defined based on what molecules are present on their surface. These markers are often
Cluster_of_differentiation
Anatomical entity
of a fibroblast and express markers such as Nestin and STRO-1 which are typical markers for dental stem cells. These cells have are highly proliferate
Dental_follicle
Mammalian protein found in Homo sapiens
Stem cell factor (also known as SCF, KIT-ligand, KL, or steel factor) is a cytokine that binds to the c-KIT receptor (CD117). SCF can exist both as a
Stem_cell_factor
embryonic-like stem cells (VSELs) are a term applied to a population of adult stem cells that share several characteristics with embryonic stem cells. Initially
Very small embryonic-like stem cells
Very_small_embryonic-like_stem_cells
Type of stem cell
Pancreatic progenitor cells are multipotent stem cells originating from the developing fore-gut endoderm which have the ability to differentiate into the
Pancreatic_progenitor_cell
Ovarian stem cells are oocytes formed in ovarian follicle before birth in female mammals. Interest has recently been devoted to OSCs (ovarian stem cells), whose
Ovarian_stem_cell
Protein found in humans
tract, testes, and some other cell types. Today CD133 is the most commonly used marker for isolation of cancer stem cell (CSC) population from different
PROM1
Early form of hematopoietic stem cells
stem cells] in murine cultures show phenotypic markers as being CD34-, CD150+, and Flt3- for LTR [long-term reconstitution]. These phenotypic markers
KSL_cells
extracting stem cells. The different cell populations, however, differ in certain aspects of their growth rate in culture, marker gene expression and cell differentiation
Dental_pulp_stem_cell
Theory of aging
The stem cell theory of aging postulates that the aging process is the result of the inability of various types of stem cells to continue to replenish
Stem_cell_theory_of_aging
Protein-coding gene in the species Homo sapiens
protein that is involved in post-transcriptional gene editing. It is a stem cell marker that controls the balance between self-renewal and terminal differentiation
Musashi-1
Bone marrow cancer in which lymphocytes are overproduced
growth and expansion of white blood cells. This manifestation typically begins with a single hematopoietic stem cell that acquires certain mutations over
Chronic_lymphocytic_leukemia
haematopoietic stem cells (HSCs). HSCs can be identified or isolated by the use of flow cytometry where the combination of several different cell surface markers is
Techniques to isolate haematopoietic stem cells
Techniques_to_isolate_haematopoietic_stem_cells
memory stem cell (TSCM) is a type of long-lived memory T cell with the ability to reconstitute the full diversity of memory and effector T cell subpopulations
T_memory_stem_cell
neuronal traits. For instance, cells in this category may initially express glial markers like GFAP and stem cell markers such as nestin and Sox2, but eventually
Subgranular_zone
Hematopoietic stem cell (HSC) mobilization is the medical process of stimulating hematopoietic stem cells to move (or "mobilize") from their native microenvironment
Hematopoietic stem cell mobilization
Hematopoietic_stem_cell_mobilization
capsule to be the site of stem cells. The renal capsule contain stain-retaining cells which exhibited markers for mesenchymal stem cells; after their removal
Renal_stem_cell
Precursor cell of skeletal muscle cells
Myosatellite cells, also known as satellite cells, muscle stem cells or MuSCs, are small multipotent cells with very little cytoplasm found in mature
Myosatellite_cell
Type of cell found in muscle tissue
Yablonka-Reuveni, Z (November 2006). "The skeletal muscle satellite cell: the stem cell that came in from the cold". Journal of Histochemistry and Cytochemistry
Muscle_cell
found in pancreatic cancers. BxPC-3 cells, along with JoPaca-1 cells, have high expression of cancer stem cell markers. BxPC-3 has been used in tumorigenicity
BxPC-3
Overview article
epigenetic markers during stem cell differentiation through in vitro differentiation of murine embryonic stem (ES) cells. Embryonic stem cells exhibit dramatic
Epigenetics in stem-cell differentiation
Epigenetics_in_stem-cell_differentiation
Type of cytotoxic lymphocyte
kill cells that are missing "self" markers of MHC class I. This role is especially important because harmful cells that are missing MHC I markers cannot
Natural_killer_cell
separates SCLD from other stem cell databases is that it allows users to edit information pertaining to cell types, markers, and lineages. The database
Stem_cell_lineage_database
Embryonic carcinoma cell line
growth. Cell cultures containing undifferentiated stem cells were isolated from the primary tumor which have a euploid karyotype. These stem cells were named
P19_cell
process in which hematopoietic stem cells (HSCs) differentiate into mature blood cell types. MEPs and other progenitor cells are characterized based on their
Megakaryocyte–erythroid progenitor cell
Megakaryocyte–erythroid_progenitor_cell
Process in developmental biology
is a type of metaplasia, which includes all cell fate switches, including the interconversion of stem cells. Current uses of transdifferentiation include
Transdifferentiation
Class of stem cells
Adult telomerase-positive stem cells (aTPSCs) are a proposed population of endogenous adult stem cells described in publications by Henry E. Young and
Adult telomerase positive stem cells
Adult_telomerase_positive_stem_cells
Human protein-coding gene
(January 2017). "The role of the cancer stem cell marker CD271 in DNA damage response and drug resistance of melanoma cells". Oncogenesis. 6 (1): e291. doi:10
Low-affinity nerve growth factor receptor
Low-affinity_nerve_growth_factor_receptor
Series of molecular signals
Schüring AN, Kiesel L (July 2008). "Increased expression of the adult stem cell marker Musashi-1 in endometriosis and endometrial carcinoma". The Journal
Notch_signaling_pathway
Biological process in animal connective tissue
epithelial cells lose their cell polarity and cell–cell adhesion, and gain migratory and invasive properties to become mesenchymal stem cells; these are
Epithelial–mesenchymal transition
Epithelial–mesenchymal_transition
Types of irreversible biochemical changes
functioning cells are unable to divide when necessary.[citation needed] An enzyme called telomerase elongates telomeres in gametes and stem cells. Telomerase
Hallmarks_of_aging
Marker in embryonic stem cells
(Zfp-42) is a known marker of pluripotency, and is usually found in undifferentiated embryonic stem cells. In addition to being a marker for pluripotency
Rex1
LIN28 is a marker of undifferentiated human embryonic stem cells and has been used to enhance the efficiency of the formation of iPS cells from human
LIN28
Type of stem cell
embryonic stem cells. The pluripotency of EpiSCs is primed pluripotency: primed to differentiate into specific cell lineages. Naïve pluripotent stem cells (e
Epiblast-derived_stem_cell
Protein-coding gene in the species Homo sapiens
Prostate stem cell antigen is a protein that in humans is encoded by the PSCA gene. This gene encodes a glycosylphosphatidylinositol-anchored cell membrane
Prostate_stem_cell_antigen
Endogenous cardiac stem cells (eCSCs) are tissue-specific stem progenitor cells harboured within the adult mammalian heart. A scientific-misconduct scandal
Endogenous_cardiac_stem_cell
biological marker used to identify hematopoietic stem cell (HSC) along with other markers. Sca-1 has a regenerative role in cardiac repair: Host cells with
Sca-1
Oogonial stem cells (OSCs), also known as egg precursor cells or female germline cells, are diploid germline cells with stem cell characteristics: the
Oogonial_stem_cells
Animal connective tissue cell
supportive "feeder cells" in research using human embryonic stem cells, induced pluripotent stem cells and primary epithelial cell culture. However, many
Fibroblast
Protein molecule receiving signals for a cell
Schild regression for ligand receptor inhibition Signal transduction Stem cell marker List of MeSH codes (D12.776) Receptor theory In the case of the receptor
Receptor_(biochemistry)
Protein complex serving as a telomere cap
S, Blasco MA (2013). "TRF1 is a stem cell marker and is essential for the generation of induced pluripotent stem cells". Nat Commun. 4: 1946. Bibcode:2013NatCo
Shelterin
Protein-coding gene in the species Homo sapiens
marker of normal and malignant human mammary stem cells and a predictor of poor clinical outcome". Cell Stem Cell. 1 (5): 555–567. doi:10.1016/j.stem
ALDH1A1
Nonprofit scientific research institute
The New York Stem Cell Foundation, or NYSCF, is an American non-profit research institute focused on stem cell research, technology development, and funding
New_York_Stem_Cell_Foundation
Three-dimensional aggregate of pluripotent stem cells
stem cells. These include embryonic stem cells (ESC) and induced pluripotent stem cells (iPSC). EBs are differentiation of human embryonic stem cells
Embryoid_body
Subtype of white blood cell
dual expressers).[citation needed] Mammalian stem cells differentiate into several kinds of blood cell within the bone marrow. This process is called
Lymphocyte
OP9 cells are a cell line derived from mouse bone marrow stromal cells (mesenchyme). These cells are now characterized as stem cells. When co-cultured
OP9_cell
Cellular process of loss of specialization
processes like direct reprogramming and the production of induced pluripotent stem cells, endogenous dedifferentiation processes also exist as a component of wound
Dedifferentiation
Global biotechnology company based in San Diego, California
tabular form. Antibodies Autophagy database Neurodegenerative disorders Stem cell marker SUMO protein WuXi PharmaTech Acquires Abgent, a Leading Producer of
Abgent
Proposed method of generating pluripotent stem cells
(STAP) was a proposed method of generating pluripotent stem cells by subjecting ordinary cells to certain types of stress, such as the application of
Stimulus-triggered acquisition of pluripotency
Stimulus-triggered_acquisition_of_pluripotency
is Essential for Intestinal Homeostasis and Maintenance of Intestinal Stem Cells". Molecular and Cellular Biology. 27 (21): 7551–7559. doi:10.1128/MCB
List of intestinal epithelial differentiation genes
List_of_intestinal_epithelial_differentiation_genes
Colony forming unit that generates myeloid cells in the bone marrow
they are thus also called common myeloid progenitor cells or myeloid stem cells. "GEMM" stands for granulocyte, erythrocyte, monocyte, megakaryocyte.
CFU-GEMM
Protein found in humans
identifies cell surface antigens. CD34 was first described as a cell surface glycoprotein on hematopoietic stem cells and functions as a cell-cell adhesion
CD34
Scientific research institute
WiCell Research Institute is a scientific research institute in Madison, Wisconsin that focuses on stem cell research. Independently governed and supported
WiCell
Mammalian protein and protein-coding gene
c-Kit. It is also a marker for mouse prostate stem cells. In addition, mast cells, melanocytes in the skin, and interstitial cells of Cajal in the digestive
KIT_gene
Measurable indicator
PMID 23335551. Nagano K, Yoshida Y, Isobe T (October 2008). "Cell surface biomarkers of embryonic stem cells". Proteomics. 8 (19): 4025–4035. doi:10.1002/pmic.200800073
Biomarker_(medicine)
generate haematopoietic stem cells at a higher rate than cells from a haematopoietic origin. Thus the co-expression of cell surface markers from both lineages
Aorta-gonad-mesonephros
Protein-coding gene in the species Homo sapiens
Clevers H (2009). "OLFM4 is a robust marker for stem cells in human intestine and marks a subset of colorectal cancer cells". Gastroenterology. 137 (1): 15–7
Olfactomedin_4
Pair of cloned sheep
embryonic stem cells can be selected in vitro before the experiment moves on further for the production of an animal. Embryonic stem cells capable of
Polly_and_Molly
Tumour-promoting cell type
either normal fibroblasts, pericytes, smooth muscle cells, fibrocytes or mesenchymal stem cells These CAFs then go on to support tumour growth by secreting
Cancer-associated_fibroblast
Medical condition
A germ cell tumor (GCT) is a neoplasm derived from primordial germ cells. Germ-cell tumors can be cancerous or benign. Germ cell tumors typically originate
Germ_cell_tumor
Type of white blood cell
of a T-cell receptor (TCR) on their cell surface. T cells are born from hematopoietic stem cells, found in the bone marrow. Developing T cells then migrate
T_cell
American surgeon
Gudas, LJ (2006). "Decreased expression of the human stem cell marker, Rex-1 (zfp-42), in renal cell carcinoma". Carcinogenesis. 27 (3): 499–507. doi:10
Douglas_Scherr
Smooth muscle cell found in testis
histochemical marker, alkaline phosphatase (stimulated by testosterone and retinol) has been useful for investigating peritubular myoid cell function and
Peritubular_myoid_cell
Medical condition
to 25% of cases the malignant cells in MEITL also express markers of B cell lymphocytes. Detection of these "tumor marker" molecules on or in the lymphocytes
Monomorphic epitheliotropic intestinal T cell lymphoma
Monomorphic_epitheliotropic_intestinal_T_cell_lymphoma
Blood cancer characterized by overproduction of lymphoblasts
Treatment can also include radiation therapy if ALL has spread to the brain. Stem cell transplantation may be used if the disease recurs following standard treatment
Acute_lymphoblastic_leukemia
Homodimeric protein enzyme
3390/molecules28186565. PMC 10536125. PMID 37764341. "Appendix E: Stem Cell Markers". Stem Cell Information. National Institutes of Health, U.S. Department
Alkaline_phosphatase
Protein-coding gene in the species Homo sapiens
Recently, Cripto-1 was proposed as cancer stem cell marker. CFC1B has oncogene potential due to the tumor cell proliferation through initiation by autocrine
Cripto
Stem cells that may cause cancer
therapy. Breast cancer stem cells establish their cell identity by expressing unique pattern of proteins and surface markers as fingerprints. Accordingly
Breast_cancer_stem_cell
Mammalian protein found in humans
conserved cell surface protein with a single V-like immunoglobulin domain, originally discovered as a thymocyte antigen. Thy-1 can be used as a marker for a
CD90
Protein-coding gene in humans
a functional marker for adult limbal stem cells of the cornea. ABCB5+ cells could regrow a human cornea on a mouse with limbal stem cell deficiency (LSCD
ABCB5
STEM CELL-MARKER
STEM CELL-MARKER
Male
English
Short form of English unisex Kelly, KELL means "bright-headed."
Boy/Male
Anglo Saxon
Stem.
Surname or Lastname
English
English : topographic name for someone who lived in a small valley, from Middle English, Old English dell ‘dell’, ‘valley’, or a habitational name from any of several minor places named Dell, from this word, for example in Buckinghamshire, Essex, and Sussex.German : from Low German delle ‘dell’, ‘depression’ (Middle High German telle ‘gorge’).
Female
English
Pet form of English Eleanor, NELL means "foreign; the other."
Male
Swedish
Swedish form of Old Norse Steinn, STEN means "stone."
Female
English
Variant spelling of English Belle, BELL means "beautiful."Â
Surname or Lastname
English (chiefly northern)
English (chiefly northern) : topographic name for someone who lived by an area of high ground or by a prominent crag, from northern Middle English fell ‘high ground’, ‘rock’, ‘crag’ (Old Norse fjall, fell).English, German, and Jewish (Ashkenazic) : metonymic occupational name for a furrier, from Middle English fell, Middle High German vel, or German Fell or Yiddish fel, all of which mean ‘skin’, ‘hide’, or ‘pelt’. Yiddish fel refers to untanned hide, in contrast to pelts ‘tanned hide’ (see Pilcher).
Boy/Male
Australian, Finnish, German, Slavic
Stem
Male
English
Variant spelling of English unisex Steph, STEF means "crown."
Male
Hebrew
(ש×Öµ×) Hebrew name SHEM means "conspicuous position, name, renown, sigma." In the bible, this is the name of a son of Noah.
Girl/Female
Gujarati, Hindu, Indian, Kannada, Malayalam, Marathi, Sanskrit, Tamil, Telugu
Lotus Stem
Surname or Lastname
English
English : topographic name for someone who lived near a spring or stream, Middle English well(e) (Old English well(a)).German : from a short form of the personal names Wallo, Walilo.German : nickname from Middle High German wël ‘round’.
Male
English
Short form of English Stewart, STEW means "steward."
Boy/Male
American, British, English
Stem
Male
English
Short form of English Stephen, STE means "crown."
Biblical
same as Shem
Boy/Male
Hindu
Lotus stem
Boy/Male
English
Austere
Boy/Male
American, Anglo, British, English
Stem
Boy/Male
Tamil
Lotus stem
STEM CELL-MARKER
STEM CELL-MARKER
Boy/Male
Greek, Indian, Punjabi, Sanskrit, Sikh, Spanish
Illusion
Boy/Male
Muslim/Islamic
Slave of the Reckoner
Female
Japanese
(è›) Japanese name HOTARU means "firefly; lightning bug."
Biblical
he that opens; that is at liberty
Boy/Male
Gujarati, Hindu, Indian, Kannada, Malayalam, Marathi, Tamil, Telugu
Boundless; Grand Son of Lord Vishnu / Krishna
Girl/Female
Australian, Chinese, Latin
Young; Jove's Child; Female Version of Julian; Youthful
Boy/Male
Gujarati, Hindu, Indian, Kannada, Malayalam, Marathi, Telugu
Kamdev; Cupid
Boy/Male
Muslim
A prophets name lot
Boy/Male
Shakespearean
King Henry V' A French herald.
Female
English
Pet form of English Jessica, JESSA means "one who beholds" or "one who looks out."
STEM CELL-MARKER
STEM CELL-MARKER
STEM CELL-MARKER
STEM CELL-MARKER
STEM CELL-MARKER
v. i.
To generate steam; as, the boiler steams well.
n.
Same as Cella.
n.
See Stee.
n.
Anything resembling a stem or stalk; as, the stem of a tobacco pipe; the stem of a watch case, or that part to which the ring, by which it is suspended, is attached.
n. & v.
See 1st and 2nd Stem.
n.
Alt. of Steem
v. t.
To oppose or cut with, or as with, the stem of a vessel; to resist, or make progress against; to stop or check the flow of, as a current.
n.
A cell; a house.
n.
A stem-winding watch.
n.
A little branch which connects a fruit, flower, or leaf with a main branch; a peduncle, pedicel, or petiole; as, the stem of an apple or a cherry.
v. t.
To remove the stem or stems from; as, to stem cherries; to remove the stem and its appendages (ribs and veins) from; as, to stem tobacco leaves.
v. t.
To place or inclose in a cell.
pl.
of Cello
a.
Containing a cell or cells.
v. i.
To emit steam or vapor.
v. t.
To make bell-mouthed; as, to bell a tube.
v. i.
Alt. of Steem
a.
Wound by mechanism connected with the stem; as, a stem-winding watch.
v. t.
To expose to the action of steam; to apply steam to for softening, dressing, or preparing; as, to steam wood; to steamcloth; to steam food, etc.