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Discontinuity in DNA strand
A nick is a discontinuity in a double stranded DNA molecule where there is no phosphodiester bond between adjacent nucleotides of one strand. They typically
Nick_(DNA)
Topics referred to by the same term
Voivodeship, Poland, a village Nick, Allied codename for Japanese World War II fighter Kawasaki Ki-45 Nick (DNA), an element of DNA structure Nickelodeon, a
Nick
English electronic music production duo
DNA was the name taken by English electronic music producers Nick Batt and Neal Slateford, best known for releasing a remix of Suzanne Vega's "Tom's Diner"
DNA_(duo)
–O– linkage between phosphoric acid and two other compounds
Phosphodiesterase Phosphodiesterase inhibitor DNA replication, DNA, ATP Teichoic acid, DNase I PDE5 Nick (DNA) "Phosphodiester bond". School of BioMedical
Phosphodiester_bond
Molecule that carries genetic information
Deoxyribonucleic acid (pronunciation; DNA) is a polymer composed of two polynucleotide chains that coil around each other to form a double helix. The
DNA
Biological process
DNA replication is the process by which a cell makes exact copies of its DNA. This process occurs in all organisms and is essential to biological inheritance
DNA_replication
Child who disappeared in Arkansas, 1995
2024). "DNA Evidence Links 1995 Suspect to Morgan Nick Disappearance". Southwest Times Record. Retrieved November 15, 2025. "The Morgan Nick Foundation:
Disappearance_of_Morgan_Nick
Protein-coding gene in the species Homo sapiens
DNA ligase 1 also DNA ligase I, is an enzyme that in humans is encoded by the LIG1 gene. DNA ligase 1 is the only known eukaryotic DNA ligase involved
DNA_ligase_1
System for fixing base errors of DNA replication
eukaryotes, newly synthesized lagging-strand DNA transiently contains nicks (before being sealed by DNA ligase) and provides a signal that directs mismatch
DNA_mismatch_repair
Class of enzymes
DNA topoisomerases (or topoisomerases) are enzymes that catalyze changes in the topological state of DNA, interconverting relaxed and supercoiled forms
Topoisomerase
Class of enzymes
which proceeds in four steps: Reorganization of activity site such as nicks in DNA segments or Okazaki fragments etc. Adenylylation (addition of AMP) of
DNA_ligase
Tagging technique in molecular biology
Nick translation (or head translation), developed in 1977 by Peter Rigby and Paul Berg, is a tagging technique in molecular biology in which DNA polymerase
Nick_translation
Molecular biology method used to detect DNA fragmentation
transferase dUTP nick end labeling (TUNEL) is a method for detecting DNA fragmentation by labeling the 3′- hydroxyl termini in the double-strand DNA breaks generated
TUNEL_assay
Endonuclease that cuts a single DNA strand
A nicking enzyme (or nicking endonuclease) is an enzyme that cuts only one strand of a double-stranded DNA or RNA molecule at a specific recognition nucleotide
Nicking_enzyme
Nb.BbvCI is a nicking endonuclease used to cut one strand of double-stranded DNA. It has been successfully used to incorporate fluorochrome-labeled nucleotides
Nb.BbvCI
American writer and death row exoneree
being wrongfully convicted of rape and murder. Yarris was exonerated by DNA testing in 2003. He was released from prison in 2004 after a separate 30-year
Nick_Yarris
Protein-coding gene in the species Homo sapiens
(ii) transfer of the adenylate group to the 5' phosphate terminus of a DNA nick; (iii) phosphodiester bond formation. Unlike LIG1 and LIG4 family members
DNA_ligase_3
colleague Ewan Birney, along with other researchers, developed a tool for DNA digital data storage, on which they successfully encoded all the sonnets
Nick_Goldman
American singer (born 1980)
titled Nick & Knight. He has also made occasional television appearances and starred in the reality shows House of Carters and I (Heart) Nick Carter.
Nick_Carter
American far-right political activist (born 1998)
for Science group, said that no vaccine would "genetically modify human DNA". Fuentes has also claimed that taking the vaccine could lead to "mandated
Nick_Fuentes
single-strand DNA transesterase enzyme produced by some prokaryotes and viruses. Relaxases are responsible for site- and strand-specific nicks in unwound
Relaxase
Cellular mechanism
DNA repair is a collection of processes by which a cell identifies and corrects damage to the DNA molecules that encode its genome. A weakened capacity
DNA_repair
Upcoming dark fantasy action film
developed by FromSoftware. It stars Kit Connor, Cailee Spaeny, Ben Whishaw, Nick Offerman, Tom Burke, Havana Rose Liu, Sonoya Mizuno, Emma Laird, Peter Serafinowicz
Elden_Ring_(film)
Protein-coding gene in the species Homo sapiens
DNA polymerase beta, also known as POLB, is an enzyme present in eukaryotes. In humans, it is encoded by the POLB gene. In eukaryotic cells, DNA polymerase
DNA_polymerase_beta
Realm of viruses
have circular single-stranded DNA (ssDNA) genomes, but some have linear ssDNA genomes or circular double-stranded DNA (dsDNA) genomes. The prototypical members
Floreoviria
Study of how temperature affects the nucleic acid structure
structure of double-stranded DNA (dsDNA). The melting temperature (Tm) is defined as the temperature at which half of the DNA strands are in the random coil
Nucleic_acid_thermodynamics
and double-stranded DNA. Some FENs can also act as 5'-3' exonucleases on the 5' terminus of the flap strand and on 'nicked' DNA substrates. Protein structure
Flap_endonuclease
Short strand of RNA or DNA that serves as a starting point for DNA synthesis
strands must be removed accurately and replaced with DNA nucleotides. This forms a gap region known as a nick that is filled in using a ligase. The removal process
Primer_(molecular_biology)
Medical condition
Aprataxin, which might help DNA repair by the removal of adenylate groups from 5′-phosphate terminus at single-strand DNA nicks and gaps. It is most common
Ataxia with oculomotor apraxia type 1
Ataxia_with_oculomotor_apraxia_type_1
Structure formed by double-stranded molecules
segments. If a nick is present, bending will be localised to the nick site. Longer stretches of DNA are entropically elastic under tension. When DNA is in solution
Nucleic_acid_double_helix
of DNA replication used by parvoviruses, a group of viruses that constitute the family Parvoviridae. Parvoviruses have linear, single-stranded DNA (ssDNA)
Rolling_hairpin_replication
American mixed martial artist
8, 2021. DNA, MMA (July 13, 2021). "Nick Diaz vs. Robbie Lawler 2 tijdens UFC 266 in Las Vegas". MMA DNA. Retrieved July 14, 2021. "UFC: Nick Diaz returns
Nick_Diaz
DNA reverse transcribed from RNA
complementary DNA (cDNA) is DNA that was reverse transcribed (via reverse transcriptase) from an RNA (e.g., messenger RNA or microRNA). cDNA exists in both
Complementary_DNA
Gene editing technique
nickase to exploit DNA repair systems by targeting the opposite non-edited strand. Following the nick on the non-edited strand, DNA repair will use the
Prime_editing
Protein-coding gene in the species Homo sapiens
DNA polymerase lambda, also known as Pol λ, is an enzyme found in all eukaryotes. In humans, it is encoded by the POLL gene. Pol λ is a member of the
DNA_polymerase_lambda
Protein-coding gene
M505277200. PMID 15964833. Mahajan KN, Nick McElhinny SA, Mitchell BS, Ramsden DA (July 2002). "Association of DNA polymerase mu (pol mu) with Ku and ligase
DNA_polymerase_mu
transfer at which site they nick DNA. The nicking domain of Reps tend to be smaller, on the order of 10-20 kDa while nicking domains from relaxases are
HUH-tag
Character in the Marvel Cinematic Universe
characters, including Nick Fury. Jackson was then offered the role, initially signing a nine-film contract with Marvel to portray Nick Fury in the Marvel
Nick Fury (Marvel Cinematic Universe)
Nick_Fury_(Marvel_Cinematic_Universe)
1998 American television movie
Nick Fury: Agent of S.H.I.E.L.D. (stylized as Nick Fury: Agent of SHIELD and Nick Fury: Agent of Shield) is a 1998 American television superhero film
Nick Fury: Agent of S.H.I.E.L.D. (film)
Nick_Fury:_Agent_of_S.H.I.E.L.D._(film)
Deputy Prime Minister of the United Kingdom from 2010 to 2015
2005). "Nick Clegg". The Daily Telegraph. London. Archived from the original on 16 May 2009. Retrieved 13 May 2009. Clegg, Nick (13 March 2011). "Nick Clegg's
Nick_Clegg
Type of DNA in bacterial genomes
stranded DNA. DNA synthesis displaces the single stranded region and then a second nick at the left border region releases the single stranded T-DNA fragment
Transfer_DNA
Process of encoding and decoding binary data to and from synthesized strands of DNA
DNA digital data storage is the process of encoding and decoding binary data to and from synthesized strands of DNA. While DNA as a storage medium has
DNA_digital_data_storage
American vocal group
Their DNA World Tour: 'Vegas Is in Our DNA'". People. Holmes, Martin (December 9, 2022). "Backstreet Boys Holiday Special Pulled by ABC Following Nick Carter
Backstreet_Boys
Type of DNA
Organellar DNA (oDNA) is DNA contained in organelles (such as mitochondria and chloroplasts), outside the nucleus of eukaryotic cells. Mitochondria contain
Organellar_DNA
Ancestor of all current life on Earth
genetic material was most likely DNA, so that it lived after the RNA world. The DNA was kept double-stranded by an enzyme, DNA polymerase, which recognises
Last universal common ancestor
Last_universal_common_ancestor
Primary enzyme complex involved in prokaryotic DNA replication
removed by DNA polymerase I via the process of nick translation. The removal of the RNA primer allows DNA ligase to ligate the DNA-DNA nick between the
DNA_polymerase_III_holoenzyme
2007 murder in Perugia, Italy
no evidential trace of Kercher's DNA had been found on the alleged murder weapon. Although the review confirmed the DNA fragments on the bra clasp included
Murder_of_Meredith_Kercher
Parts of lagging strand in DNA replication
5' end of the DNA flap is blocked either with a complementary primer or a biotin-conjugated streptavidin moiety. DNA ligase seals the nick made by the FEN1
Okazaki_fragments
Human Y-chromosome DNA haplogroup
J-M267, also commonly known as Haplogroup J1, is a subclade (branch) of Y-DNA haplogroup J-P209 (commonly known as haplogroup J) along with its sibling
Haplogroup_J-M267
American mixed martial arts fighter
Nick Maximov (born December 23, 1997) is an American mixed martial artist who competed in the Middleweight division of the Ultimate Fighting Championship
Nick_Maximov
American scientist and entrepreneur
Villeponteau, B., and Martinson, H.G. (1987). Gamma rays and bleomycin nick DNA and reverse the DNase I sensitivity of beta-globin gene chromatin in vivo
Bryant_Villeponteau
Protein-coding gene in the species Homo sapiens
component of the SET complex, and acts to rapidly degrade 3' ends of nicked DNA during granzyme A-mediated cell death. Mutations in this gene result in
TREX1
American writer and activist (born 1987)
fingerprints, and DNA were found in Kercher's bedroom. Guede's DNA was on the strap of Kercher's bra, which had been torn off, and his DNA was found on a
Amanda_Knox
Quadruple stabbing in Moscow, Idaho, U.S.
leather knife sheath on a bed next to one of the victims, which yielded touch DNA matching a single male profile. Surveillance footage collected from surrounding
2022_Idaho_student_murders
DNA replication in prokaryotes
and DNA Polymerase I (exonuclease), and the gaps (or nicks) are filled with deoxyribonucleotides and sealed by the enzyme ligase. The rate of DNA replication
Prokaryotic_DNA_replication
Film by Bart Layton
film also features Monica Barbaro, Corey Hawkins, Jennifer Jason Leigh, and Nick Nolte. A co-production between the United States and the United Kingdom,
Crime_101_(2026_film)
alpha-2,3-sialyltransferase - nested PCR - neurofibromatosis - NH41 - nick (DNA) - nick translation - NIDDM1 - Niemann-Pick disease, type C - nitrate-transporting
Index of molecular biology articles
Index_of_molecular_biology_articles
Soap opera character
raped by Matt. Nick ran to confront Matt at his apartment, only to discover Matt lying in a pool of blood having been shot. Nick's DNA was found on the
Nick_and_Sharon
Indian actress and model
Retrieved 28 December 2023. "'TMKOC' fame Munmun Dutta aka Babita ji arrested". DNA. 7 February 2022. Archived from the original on 7 February 2022. Retrieved
Munmun_Dutta
DNA replication in eukaryotic organisms
Eukaryotic DNA replication is a conserved mechanism that restricts DNA replication to once per cell cycle. Eukaryotic DNA replication of chromosomal DNA is central
Eukaryotic_DNA_replication
Technique to separate DNA or RNA fragments
supercoiled form, while other forms of DNA may appear as minor fainter bands. These minor bands may be nicked DNA (open circular form) and the relaxed closed
Gel electrophoresis of nucleic acids
Gel_electrophoresis_of_nucleic_acids
Method for separation and analysis of biomolecules using agarose gel
normally show the negatively supercoiled form as the main band, while nicked DNA (open circular form) and the relaxed closed circular form appears as minor
Agarose_gel_electrophoresis
Amount of twist in a particular DNA strand
DNA supercoiling refers to the amount of twist in a particular DNA strand, which determines the amount of strain on it. A given strand may be "positively
DNA_supercoil
Technique for joining nucleic acid fragments
end of a DNA strand on the activated 5′-phosphoryl group of another. A nick in the DNA (i.e. a break in one strand of a double-stranded DNA) can be repaired
Ligation_(molecular_biology)
Method of bacterial gene transfer
and brings the two cells together. The mobile plasmid is nicked and a single strand of DNA is then transferred to the recipient cell. Both cells synthesize
Bacterial_conjugation
Gene editing method
targeted DNA damage and repair. HDR employs the use of similar DNA sequences to drive the repair of the break via the incorporation of exogenous DNA to function
CRISPR_gene_editing
Type of database
A DNA database or DNA databank is a database of DNA profiles which can be used in the analysis of genetic diseases, genetic fingerprinting for criminology
DNA_database
Separation or breakage of DNA strands into pieces
method fragments DNA either by the simultaneous cleavage of both strands, or by generation of nicks on each strand of dsDNA to produce dsDNA breaks. Acoustic
DNA_fragmentation
DNA-based genetic test
A genealogical DNA test is a DNA-based genetic test used in genetic genealogy that looks at specific locations of a person's genome in order to find or
Genealogical_DNA_test
Nicking Enzyme Amplification Reaction (NEAR) is a method for in vitro DNA amplification like the polymerase chain reaction (PCR). NEAR is isothermal,
Nicking enzyme amplification reaction
Nicking_enzyme_amplification_reaction
Comic book character
S. Army hero/super-spy and the intelligence agency S.H.I.E.L.D. director Nick Fury. The character first appeared in Battle Scars #1 (January 2012), which
Nick_Fury_Jr.
Research laboratory at Harvard Medical School in Boston, Massachusetts, U.S.
aim is to create an "Ancient DNA Atlas of Humanity". Major areas of focus include: Ancient DNA: Recovery and analysis of DNA from ancient human remains
David_Reich_Lab
Replication of DNA
DNA synthesis is the natural or artificial creation of deoxyribonucleic acid (DNA) molecules. DNA is a macromolecule made up of nucleotide units, which
DNA_synthesis
DNA synthesis technique
proceeds around the circular DNA molecule, displacing the nicked strand as single-stranded DNA. Displacement of the nicked strand is carried out by a host-encoded
Rolling_circle_replication
2015 murders in Switzerland
the arrest in a Starbucks in Aarau of a 33-year-old student, Thomas Nick. His DNA as well as his fingerprints were identified at the crime location, and
Rupperswil_murder_case
German mixed martial artist and actor
fantastic on the floor, finishes Nick Hein in first". MMAjunkie. 2018-05-13. Retrieved 2018-05-13. DNA, MMA (5 June 2018). "Nick Hein maakt snelle comeback
Nick_Hein
DNA analysis of Jewish populations
using all three types of genealogical DNA tests: autosomal (atDNA), mitochondrial (mtDNA), and Y-chromosome (Y-DNA). Autosomal testing, which looks at the
Genetic_studies_of_Jews
American animated television series
series created by John A. Davis for Nickelodeon. The series was produced by DNA Productions alongside O Entertainment and Nickelodeon Animation Studio. It
The Adventures of Jimmy Neutron, Boy Genius
The_Adventures_of_Jimmy_Neutron,_Boy_Genius
American gangster (1942–2023)
also had spread out across the country with search warrants, collecting DNA evidence, hair cuttings and oral swabs from many reputed Chicago Outfit members
Nicholas_Calabrese
(1970), biochemist who was the first to purify and characterize DNA polymerase II and DNA polymerase III Harold J. Vinegar (1970), former chief scientist
List of Columbia College people
List_of_Columbia_College_people
2009 action thriller film by F. Gary Gray
front of him. Prosecutor Nick Rice is assigned to the case along with District Attorney Jonas Cantrell. Upon learning that the DNA evidence is inconclusive
Law_Abiding_Citizen
Human Y-chromosome DNA haplogroup
Haplogroup R1a (R-M420), is a human Y-chromosome DNA haplogroup which is distributed in a large region in Eurasia, extending from Scandinavia and Central
Haplogroup_R1a
Archaic human species from Asia
mitochondrial DNA (mtDNA) extracted from a juvenile finger bone excavated from the Siberian Denisova Cave in the Altai Mountains in 2008. Nuclear DNA indicates
Denisovan
English actor (born 2004)
English actor. He gained recognition for starring as secondary school student Nick Nelson in the Netflix teen series Heartstopper (2022–2024) and its series
Kit_Connor
Branched nucleic acid structure
These junctions also later found use as basic structural building blocks in DNA nanotechnology, where multiple Holliday junctions can be combined into specific
Holliday_junction
DNA profiling technique
DNA amplification fingerprinting (DAF) is a highly sensitive DNA profiling technique that generates complex, reproducible genomic fingerprints without
DNA amplification fingerprinting
DNA_amplification_fingerprinting
Type of paternal lineage
Bhutan, Ladakh, Tajikistan, Turkey, and Western China. According to ancient DNA studies, most R1a and R1b lineages would have expanded from the Pontic Steppe
Haplogroup_R1b
Molecular complex
molecular machine that carries out replication of DNA. The replisome first unwinds double stranded DNA into two single strands. For each of the resulting
Replisome
2024 Marvel Studios film
self-awareness, violence, and foul language. He did not want to alter the franchise's DNA and called the new film "raw, audacious, [and] very much R-rated", comparing
Deadpool_&_Wolverine
Fictional character on Law & Order: Special Victims Unit
degree holder working for a company that specializes in analyzing cold-case DNA with new technologies, which bring him back to Manhattan in order to clear
Nick_Amaro
Single-stranded DNA virus that infects bacteria
stranded supercoiled genome is nicked on the positive strand by a virus-encoded A protein, also attracting a bacterial DNA polymerase (DNAP) to the site
Phi_X_174
DNA polymerases that originate from thermophiles
Thermostable DNA polymerases are DNA polymerases that originate from thermophiles, usually bacterial or archaeal species, and are therefore thermostable
Thermostable_DNA_polymerase
Bergman (Jurassic World Camp Cretaceous) Mr. DNA is a cartoon character that resembles an anthropomorphic DNA helix with a face and arms. He is the mascot
List of Jurassic Park (franchise) characters
List_of_Jurassic_Park_(franchise)_characters
Bocaparvoviruses known to infect humans
site-specific nicking of viral duplex DNA replication intermediates, processes that require ATP for tight binding and subsequent nicking. The NS1 protein
Human_bocavirus
2019–23 concert tour by the Backstreet Boys
The DNA World Tour was the tenth concert tour by American vocal group Backstreet Boys in support of their tenth studio album, DNA (2019). The tour performed
DNA_World_Tour
2007 American TV series or program
and final installment of the Species franchise. The film was directed by Nick Lyon and stars Ben Cross, Helena Mattsson, Dominic Keating and Marlene Favela
Species_–_The_Awakening
Type of transposable element in genomes
mechanism. This process involves making a nick to a circular strand by an enzyme, which separates the DNA into two single strands. The initiation protein
DNA_transposon
Nicholaus Goossen (director); Allen Covert, Nick Swardson, Barry Wernick (screenplay); Allen Covert, Doris Roberts, Nick Swardson, Linda Cardellini, Shirley Jones
List of American films of 2006
List_of_American_films_of_2006
Y-chromosome DNA haplogroup
Haplogroup R1, or R-M173, is a Y-chromosome DNA haplogroup. A primary subclade of Haplogroup R (R-M207), it is defined by the SNP M173. The other primary
Haplogroup_R1
Removal of a methyl group from nucleotides in DNA
in mammals, DNA demethylation causes replacement of 5-methylcytosine (5mC) in a DNA sequence by cytosine (C) (see figure of 5mC and C). DNA demethylation
DNA_demethylation
NICK DNA
NICK DNA
NICK DNA
NICK DNA
NICK DNA
NICK DNA
NICK DNA
NICK DNA
NICK DNA