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Protein-coding gene in the species Homo sapiens
Netrin receptor DCC, also known as DCC, or colorectal cancer suppressor is a protein which in humans is encoded by the DCC gene. DCC has long been implicated
Netrin_receptor_DCC
Topics referred to by the same term
DCC may refer to: Netrin receptor DCC, human receptor protein, and the gene encoding it Dosage compensation complex Day Chocolate Company DCC plc, an
DCC
Class of proteins involved in axon guidance
netrin-3 have noticed a reduced ability to bind with DCC when compared with netrin-1. This suggests that it mainly operates through other receptors.
Netrin
Protein-coding gene in the species Homo sapiens
Culotti JG, et al. (October 1996). "Deleted in Colorectal Cancer (DCC) encodes a netrin receptor". Cell. 87 (2): 175–185. doi:10.1016/S0092-8674(00)81336-7.
Netrin_1
Protein family
UNC-5 is a receptor for netrins including UNC-6. Netrins are a class of proteins involved in axon guidance. UNC-5 uses repulsion to direct axons while
UNC-5
Large actin extension of a developing neurite seeking its synaptic target
prime example of this is Netrin-1, which signals attraction through the Netrin receptor DCC and repulsion through the UNC-5 receptor. Furthermore, it has
Growth_cone
Protein-coding gene in the species Homo sapiens
Netrin receptor UNC5C is a protein that in humans is encoded by the UNC5C gene. This gene product belongs to the UNC-5 family of netrin receptors. Netrins
UNC5C
Protein-coding gene in the species Homo sapiens
Netrin receptor UNC5A is a protein that in humans is encoded by the UNC5A gene. UNC5A belongs to a family of netrin-1 (MIM 601614) receptors thought to
UNC5A
(Dec 1997). "Turning of retinal growth cones in a netrin-1 gradient mediated by the netrin receptor DCC". Neuron. 19 (6): 1211–24. doi:10.1016/S0896-6273(00)80413-4
Tropic cues involved in growth cone guidance
Tropic_cues_involved_in_growth_cone_guidance
British developmental neuroscientist
(December 1997). "Turning of Retinal Growth Cones in a Netrin-1 Gradient Mediated by the Netrin Receptor DCC". Neuron. 19 (6): 1211–1224. doi:10.1016/S0896-6273(00)80413-4
Christine_Holt
Neuroscience field
molecules and their receptors: Netrins: Netrins are secreted molecules that can act to attract or repel axons by binding to their receptors, DCC and UNC-5. Slits:
Axon_guidance
Embryonic structure
Slit acts through its receptors Roundabout (Robo) 1 and 2. This interaction inhibits the chemotaxis provided by the Netrin/DCC pathway. However, Robo-3
Floor_plate_(biology)
Formation of neuronal junctions in the nervous system
repulsive receptors for FLRTs. Besides guidance cues, NTNs and FLRTs are also involved in synaptic specificity and synaptogenesis. In studying Netrin, one
Synaptogenesis
Proteins that mediate programmed cell death
following is the list of known dependence receptors: Notch3 Kremen1 DCC (Deleted in Colorectal Carcinoma) UNC5 receptors (UNC5A, UNC5B, UNC5C, UNC5D) Neogenin
Dependence_receptor
Type of cell within the eye
express local gradients of Netrin-1, a morphogen that will interact with the Deleted in Colorectal Cancer (DCC) receptor on growth cones of the RGC axon
Retinal_ganglion_cell
Protein-coding gene in the species Homo sapiens
Culotti JG, et al. (1996). "Deleted in Colorectal Cancer (DCC) encodes a netrin receptor". Cell. 87 (2): 175–185. doi:10.1016/S0092-8674(00)81336-7.
NEO1
French biologist
interested in receptors that bind to the netrin-1 ligand -i.e., DCC and UNC5H-. They have shown that DCC and UNC5H are all dependency receptors in cancer
Patrick_Mehlen
Long projection on a neuron that conducts signals to other neurons
ligand-gated association between cytoplasmic domains of UNC5 and DCC family receptors converts netrin-induced growth cone attraction to repulsion". Cell. 97 (7):
Axon
Medical condition
include DCC (deleted in colorectal carcinoma), DNAL4 (dynein axonemal light chain 4), and RAD51 (recombination protein A). DCC encodes a receptor for NTN1
Congenital mirror movement disorder
Congenital_mirror_movement_disorder
Set of proteins
genetic defect. Such proteins include UNC-5, a receptor for UNC-6 which is one of the netrins. Netrins are a class of proteins involved in axon guidance
UNC_(biology)
American neuroscientist and geneticist
gene. The gene product of Unc5c is the Unc5c protein, a neurological netrin receptor. Her research on Unc5c protein revealed that the protein is integral
Susan Ackerman (neuroscientist)
Susan_Ackerman_(neuroscientist)
Involuntary muscle contraction in response to another muscle moving
are in the DCC (gene) or RAD51 gene, which account for about 35 percent of cases. In DCC mutation, impaired or missing netrin 1 receptor protein impairs
Synkinesis
Protein-coding gene in humans
Hong Y, Sun DM, Zhao ZQ, et al. (November 2004). "Focal adhesion kinase in netrin-1 signaling". Nature Neuroscience. 7 (11): 1204–1212. doi:10.1038/nn1330
PTK2
Protein involved in DNA repair
neurons, a novel role for Rad51 has been identified in the regulation of Netrin signalling and axon misguidance phenotypes. This role is not clearly linked
RAD51
Protein-coding gene in the species Homo sapiens
major class of cell adhesion receptor, and to the cytoplasmic domains of the netrin receptors Deleted in Colorectal Cancer (DCC) and neogenin (Neo1). Although
MYO10
NETRIN RECEPTOR-DCC
NETRIN RECEPTOR-DCC
Female
Greek
Feminine form of Greek Nêreus, NERINE means "daughter of Nereus" or "sea sprite" or "wet one." It is also the name of a genus of plants native to South Africa but now spread worldwide. It is a bulb plant that produces beautiful pink funnel-shaped flowers in the fall, similar to the Belladonna Lily, though smaller. In use by the English.
Female
Persian/Iranian
(نسرین) Persian name NASRIN means "wild rose."
Male
Welsh
Late variant spelling of Welsh Neirin, possibly derived from a word related to Irish Gaelic nár, ANEIRIN means "modest, noble."Â
Female
German
Pet form of German Katarine, KATRIN means "pure."
Male
Welsh
Variant spelling of Welsh Aneirin, ANEURIN means "modest, noble."
Boy/Male
Arabic
Educator; Preceptor
Female
Turkish
Turkish form of Persian Nasrin, NESRIN means "wild rose."
Male
Welsh
Older form of Welsh Aneirin, possibly derived from a word related to Irish Gaelic nár, NEIRIN means "modest, noble." Neirin ap Dwywei was the name of the Welsh poet who wrote the Book of Aneirin and Y Gododdin.
Surname or Lastname
English and French
English and French : from the Middle English, Old French personal name Perrin, a pet form of French Pierre (see Peter).A Perrin from Brittany is documented in Montreal in 1661. Secondary surnames associated with Perrin are Garao, Duteau, and Languedoc.
Girl/Female
Gujarati, Indian, Sanskrit
Beautiful Eyes
Female
Welsh
Welsh form of Old French Caterine, CATRIN means "pure."
Girl/Female
Indian
A field of wild roses
Female
Italian
Feminine form of Italian Nerio, NERINA means "water."
Girl/Female
Australian, Celtic, Irish
Peace; An Ancient and Poetic Name for Ireland; Form of Erin
Girl/Female
Muslim
A field of wild roses
Male
Welsh
Welsh name derived from the Celtic byname Cethin, GETHIN means "dark, swarthy."
Male
French
Pet form of French Pierre, PERRIN means "rock, stone."
Girl/Female
Arabic, Australian, German, Muslim, Turkish
Field of Wild Roses
Girl/Female
Muslim/Islamic
A field of wild roses
Boy/Male
Indian, Sanskrit
The Preceptor
NETRIN RECEPTOR-DCC
NETRIN RECEPTOR-DCC
NETRIN RECEPTOR-DCC
NETRIN RECEPTOR-DCC
NETRIN RECEPTOR-DCC
NETRIN RECEPTOR-DCC
NETRIN RECEPTOR-DCC