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American neuroscientist and geneticist
centered largely on the Unc5c gene. The gene product of Unc5c is the Unc5c protein, a neurological netrin receptor. Her research on Unc5c protein revealed that
Susan Ackerman (neuroscientist)
Susan_Ackerman_(neuroscientist)
Protein-coding gene in the species Homo sapiens
Netrin receptor UNC5C is a protein that in humans is encoded by the UNC5C gene. This gene product belongs to the UNC-5 family of netrin receptors. Netrins
UNC5C
Protein-coding gene in the species Homo sapiens
netrin-1 on specific axons. For more information on UNC5 proteins, see UNC5C (MIM 603610).[supplied by OMIM] UNC5A has been shown to interact with MAGED1
UNC5A
Proteins that mediate programmed cell death
Kremen1 DCC (Deleted in Colorectal Carcinoma) UNC5 receptors (UNC5A, UNC5B, UNC5C, UNC5D) Neogenin p75NTR Ptch1 CDON PLXND1 RET TrkA TrkC EphA4 c-Met Insulin
Dependence_receptor
Protein domain
ROR1, ROR2, SDK1, SDK2, SIGLEC1, SIGLEC6, SPEG, TRIO, TTN, UNC5A, UNC5B, UNC5C, VCAM1, WFIKKN1, WFIKKN2, Plotnikov AN, Hubbard SR, Schlessinger J, Mohammadi
Immunoglobulin_I-set_domain
Human chromosome
protein UGDH antisense RNA 1 UGT8: UDP glycosyltransferase 8 UNC5C: netrin receptor UNC5C UPF0602: encoding UPF0602 Protein C4orf47 USP38: encoding protein
Chromosome_4
French cell biologist (born 1968)
Ackerman, S. L., Scoazec, J. Y., & Mehlen, P. (2007). Inactivation of the UNC5C Netrin-1 receptor is associated with tumor progression in colorectal malignancies
Agnès_Bernet
Each side of the forebrain represents the opposite side of the body
mammalian Trochlear and Phrenic nerves: Dependence on the Netrin receptor Unc5c and modifier loci". J. Neurosci. 26 (21): 5756–5766. doi:10.1523/JNEUROSCI
Contralateral_brain
Protein domain
SPON2; SSPO; THBS1; THBS2; THSD1; THSD3; THSD7A; THSD7B; UNC5A; UNC5B; UNC5C; UNC5D; WISP1; WISP2; WISP3; Morris, Aaron H.; Kyriakides, Themis R. (July
Thrombospondin
Protein-coding gene in the species Homo sapiens
Liu X, Tang B, et al. (October 2014). "Investigation of TREM2, PLD3, and UNC5C variants in patients with Alzheimer's disease from mainland China". Neurobiology
PLD3
P11172 17887 UNC5A HGNC:12567; Q6ZN44 17888 UNC5B HGNC:12568; Q8IZJ1 17889 UNC5C HGNC:12569; O95185 17890 UNC5CL HGNC:21203; Q8IV45 17891 UNC5D HGNC:18634;
List of human protein-coding genes 8
List_of_human_protein-coding_genes_8
Protein-coding gene in the species Homo sapiens
S2CID 9350364. Grady WM (December 2007). "Making the case for DCC and UNC5C as tumor-suppressor genes in the colon". Gastroenterology. 133 (6): 2045–9
Netrin_receptor_DCC
French biologist
cell death commitment », PNAS, 2003 Bernet et al., « Inactivation of the UNC5C Netrin-1 receptor is associated with tumor progression in colorectal malignancies »
Patrick_Mehlen
UNC5C
UNC5C
UNC5C
UNC5C
UNC5C
UNC5C
UNC5C
UNC5C
UNC5C