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Smooth muscle coat of the uterus
The myometrium is the middle layer of the uterine wall, consisting mainly of uterine smooth muscle cells (also called uterine myocytes) but also of supporting
Myometrium
Extension of endometrial tissue into the myometrium
(endometrium) atypically located among the cells of the uterine wall (myometrium), as a result, thickening of the uterus occurs. As well as being misplaced
Adenomyosis
Medical condition
that occurs when all or part of the placenta attaches abnormally to the myometrium (the muscular layer of the uterine wall) during pregnancy. This condition
Placenta_accreta_spectrum
Benign smooth-muscle tumors of the uterus
growth interacting factor (TGIF) is increased in leiomyoma compared with myometrium. TGIF is a potential repressor of TGF-β pathways in myometrial cells.
Uterine_fibroid
Medical condition
(abruptio placentae) causes bleeding that penetrates into the uterine myometrium forcing its way into the peritoneal cavity. This condition makes the uterus
Couvelaire_uterus
Female sex organ in mammals
to the embryo and fetus. The myometrium of the uterus mostly consists of smooth muscle. The innermost layer of myometrium is known as the junctional zone
Uterus
Uterine cancer that is located in tissues lining the uterus
progression of the disease, the myometrium is infiltrated. A stage III endometrioid adenocarcinoma that has invaded the myometrium Metastatic endometrial cancer
Endometrial_cancer
Medical condition
placenta percreta, the chorionic villi have grow entirely through the myometrium and invade into the perimetrium. Placenta percreta results in the most
Antepartum_bleeding
Blood vessel
arteries and veins, and penetrate and assume a circumferential course in the myometrium. They have also been called helicine branches of the uterus (or helicine
Arcuate_vessels_of_uterus
Contraction of the uterus
contractile waves, appear to involve only the sub-endometrial layer of the myometrium. In the early follicular phase, uterine contractions in the non-pregnant
Uterine_contraction
Lining of the mammalian uterus
completely shed during menstruation. The basal layer, adjacent to the myometrium and below the functional layer, is not shed at any time during the menstrual
Endometrium
Medical disorder of the uterus
as a Cesarean scar defect or an isthmocele, is an indentation of the myometrium at the site of a cesarean section with a depth of at least 2 mm. A niche
Uterine_niche
the female reproductive system, is composed of the myometrium and the endometrium. The myometrium is made of smooth tissue and the endometrium lines the
Endometrial_arteries
Inferior-posterior part of uterus
inferior-posterior part of uterus, on its cervical end — here, the uterine muscle (myometrium) is narrower and thinner. It connects the body and cervix. The uterine
Uterine_isthmus
Uterine malformation
further contractions cause the upper uterine segment muscle fibers' myometrium to shorten, so that the actively contracting upper segment becomes thicker
Bandl's_ring
Plastic surgery procedure for altering the labia minora
Vacuum aspiration Endometrium: Endometrial biopsy Endometrial ablation Myometrium: Uterine myomectomy Cervix: Colposcopy Cervical conization LEEP Cervical
Labiaplasty
External genitalia of the female mammal
Internal os External os Supravaginal portion Horns Layers Wall Endometrium Myometrium Perimetrium Parametrium Epithelium Ligaments Round ligaments Broad ligaments
Vulva
Act of lengthening the labia minora
Internal os External os Supravaginal portion Horns Layers Wall Endometrium Myometrium Perimetrium Parametrium Epithelium Ligaments Round ligaments Broad ligaments
Labia_stretching
Young of domestic cattle
leading to the expulsion of the fetus. The uterine muscle contractions, or myometrium, facilitate the calf's progression through the pelvic canal during calving
Calf_(animal)
Inflammation of the lining of the uterus
"endomyometritis" may be used when inflammation of the endometrium and the myometrium is present. The condition is also relatively common in other animals such
Endometritis
Liquid mixture produced by the vagina
Other Metropathia haemorrhagica Female infertility Recurrent miscarriage Myometrium Adenomyosis Uterine fibroid Parametrium Parametritis Cervix Cervical cancer
Vaginal_discharge
Medical condition
a tumor composed of endometrial gland tissue and smooth muscle in the myometrium. Adenomyomas containing endometrial glands are also found outside of the
Adenomyoma
Mammalian protein found in humans
a role inhibiting contractions, through increasing cAMP levels in the myometrium. In culture, trophoblast CRH is inhibited by progesterone, which remains
Corticotropin-releasing hormone
Corticotropin-releasing_hormone
Protein found in humans
tail of epididymis right coronary artery seminal vesicula gastric mucosa myometrium urethra Top expressed in ascending aorta tunica media of zone of aorta
Calponin_1
Medical condition
Other Metropathia haemorrhagica Female infertility Recurrent miscarriage Myometrium Adenomyosis Uterine fibroid Parametrium Parametritis Cervix Cervical cancer
Vaginal_stenosis
Medical condition
Leiomyosarcomas originate from the muscular layer of the uterus (or myometrium). Of note, leiomyosarcomas are distinct from uterine leiomyomas, which
Uterine_cancer
Reproductive system of female humans
19. Cervical canal; 20. Uterine cavity; Layers: 21. Endometrium; 22. Myometrium and 23. Perimetrium 24. Fallopian tube: 25. Isthmus; 26. Ampulla; 27. Infundibulum;
Female_reproductive_system
Protein-coding gene in the species Homo sapiens
aorta Descending thoracic aorta left coronary artery tail of epididymis myometrium urethra Top expressed in tunica media of zone of aorta ascending aorta
Transgelin
Protein found in humans
epithelium of colon hair follicle buccal mucosa cell left ovary right ovary myometrium testicle Top expressed in zygote oocyte secondary oocyte primary oocyte
Zinc finger protein basonuclin-2
Zinc_finger_protein_basonuclin-2
Protein-coding gene in humans
expression pattern Bgee Human Mouse (ortholog) Top expressed in endometrium myometrium placenta smooth muscle tissue canal of the cervix human kidney body of
AADACL4
Protein-coding gene in the species Homo sapiens
cortex gastric mucosa right auricle of heart body of uterus left ovary myometrium tibial nerve Top expressed in ankle joint ankle extraocular muscle sciatic
Tenascin_X
Concave variant of uterine cavity shape
the fundus on anterior-posterior imaging, but in the arcuate uterus the myometrium of the fundus dips into the cavity and may form a small septation. The
Arcuate_uterus
Primary female sex hormone
during gestation period. It also upregulates oxytocin receptors in the myometrium. Estrogens are heavily involved in energy homeostasis and metabolism.
Estrogen
Part of uterus modified in pregnancy
Intermediate layer (stratum spongiosum) Boundary layer adjacent to the myometrium (stratum basalis) Within the decidua, occasional fibrinoid deposits form
Decidua
cells. Expression of TGIF is increased in uterine leiomyoma compared with myometrium. Yen-Ping Ho J, Man WC, Wen Y, Polan ML, Shih-Chu Ho E, Chen B (June 2009)
Transforming growth interacting factor
Transforming_growth_interacting_factor
Ejection of the placenta from the uterus after childbirth
mechanisms. The end pathway of both mechanisms lead to contractions in the myometrium, a mechanical cause of placental separation, which is due to the sheer
Placental_expulsion
Mass on the interior lining of the uterus
Myometrium (smooth muscle cells) versus endometrial stroma (more cellular) versus endometrial polyp stroma (more collagenous). H&E stain
Endometrial_polyp
Chemical compound
medicine under the trade name Sensiblex as a muscle relaxant for the myometrium of cows and dogs during parturition. Under the trade name Spasmalgan,
Denaverine
Female reproductive organ that produces egg cells
Internal os External os Supravaginal portion Horns Layers Wall Endometrium Myometrium Perimetrium Parametrium Epithelium Ligaments Round ligaments Broad ligaments
Ovary
Form of uterine cancer
uterus IA: limited to endometrium/endocervix IB: invades <½ myometrium IC: invades ≥½ myometrium Finally, malignant mixed Müllerian tumors, a type of carcinosarcoma
Uterine_sarcoma
Phase of the estrous or menstrual cycle
estrogen levels in the blood stimulates growth of the endometrium and myometrium of the uterus. It also causes endometrial cells to produce receptors for
Follicular_phase
Protein-coding gene in the species Homo sapiens
uterus synovial joint Achilles tendon left uterine tube caput epididymis myometrium saphenous vein synovial membrane Top expressed in adrenal gland facial
RERG
Human body part
Internal os External os Supravaginal portion Horns Layers Wall Endometrium Myometrium Perimetrium Parametrium Epithelium Ligaments Round ligaments Broad ligaments
Perineal_raphe
Gynecological sterilization operation
operation, the proximal part of fallopian tube is buried back into the myometrium, thereby obstructing its lumen. The Irving operation was proposed by Dr
Irving_operation
Interstitial cells
Sanda M.; Creţoiu, Dragos; Popescu, Laurentiu M. (November 2012). "Human myometrium - the ultrastructural 3D network of telocytes". Journal of Cellular and
Telocyte
Non-coding RNA in the species Homo sapiens
uterine tube tibial arteries muscle layer of sigmoid colon body of uterus myometrium left coronary artery prostate n/a More reference expression data BioGPS
Mir-145
Chemical compound
endometrium, and the lining of the fallopian tubes. It enhances growth of the myometrium. Estradiol appears necessary to maintain oocytes in the ovary. During
Estradiol
Small nucleolar RNA in humans
Human Mouse (ortholog) Top expressed in sural nerve liver Achilles tendon myometrium lung heart Brodmann area 9 islet of Langerhans stomach left ventricle
SNORD24
Protein-coding gene in the species Homo sapiens
mRNA and protein expression of SFRP1 in leiomyomas and matched normal myometrium. The following outlines their findings: Twenty-three out of 25 patients
Secreted frizzled-related protein 1
Secreted_frizzled-related_protein_1
Structure derived from the corpus luteum
Internal os External os Supravaginal portion Horns Layers Wall Endometrium Myometrium Perimetrium Parametrium Epithelium Ligaments Round ligaments Broad ligaments
Corpus_albicans
Medical condition
Internal os External os Supravaginal portion Horns Layers Wall Endometrium Myometrium Perimetrium Parametrium Epithelium Ligaments Round ligaments Broad ligaments
Ovarian_remnant_syndrome
Layer of an embryo
cells may invade the whole endometrium and the proximal third of the myometrium. Once these cells penetrate through the first few layers of cells of the
Cytotrophoblast
Protein-coding gene in the species Homo sapiens
in buccal mucosa cell testicle endometrium gonad prostate renal cortex myometrium hepatobiliary system skeletal muscle smooth muscle tissue n/a More reference
MMP26
sinus testicle visceral pleura smooth muscle tissue left adrenal cortex myometrium body of uterus saphenous vein Top expressed in molar body of femur calvaria
CCN_family_member_4
Pseudogene in the species Homo sapiens
11.005. PMID 16406723. Parker JD, Malik M, Catherino WH (2007). "Human myometrium and leiomyomas express gonadotropin-releasing hormone 2 and gonadotropin-releasing
GNRHR2
Steroid hormone that activates the progesterone receptor
Runnebaum B, Lisboa BP (July 1977). "New progesterone metabolites in human myometrium". Steroids. 30 (1): 1–14. doi:10.1016/0039-128X(77)90131-3. PMID 919010
Progestogen
System of standardizing research reporting on pelvic organ prolapse
Other Metropathia haemorrhagica Female infertility Recurrent miscarriage Myometrium Adenomyosis Uterine fibroid Parametrium Parametritis Cervix Cervical cancer
Pelvic Organ Prolapse Quantification System
Pelvic_Organ_Prolapse_Quantification_System
Type of cancer of the uterus
IA: tumor is limited to less than half the myometrium Stage IB: invasion of more than half the myometrium Stage II: cervical stromal invasion Stage IIIA:
Uterine_serous_carcinoma
Natural changes in the human female reproductive system
relaxin (which relaxes the uterus by inhibiting contractions of the myometrium), and inhibin (which inhibits further secretion of FSH). The release of
Menstrual_cycle
Amnion and chorion which surround and protect a developing fetus
The amnion is vital in the synthesis of prostaglandins which reach the myometrium and create and initiate parturition. The chorion expresses chemicals that
Fetal_membranes
Tubes in the human female reproductive system
intramural part or interstitial part of the fallopian tube lies in the myometrium, the muscular wall of the uterus. This is the narrowest part of the tube
Fallopian_tube
Protein in Homo sapiens
body of uterus left ovary superior frontal gyrus canal of the cervix myometrium Top expressed in primary visual cortex dentate gyrus of hippocampal formation
SYNGAP1
Loss of tone in the uterine musculature
The uterus is composed of interconnected muscle fibers known as the myometrium. The blood vessels that provide the blood supply to the placenta pass
Uterine_atony
Protein-coding gene in the species Homo sapiens
vesicula nucleus accumbens putamen caudate nucleus ganglionic eminence myometrium periodontal fiber tail of epididymis entorhinal cortex body of uterus
TMEM158
Genes on human chromosome 3
expressed by the myoepithelial cells of the mammary gland, and in both the myometrium and endometrium of the uterus at the end of pregnancy. The oxytocin receptor
Oxytocin_receptor
Protein-coding gene in the species Homo sapiens
pleura testicle skin of hip parietal pleura body of uterus gallbladder myometrium Top expressed in testicle spermatocyte stomach ventricle of the heart
PRND
Birth control method taken orally
to suppress the growth the endometrial tissue that has grown into the myometrium. Unlike endometriosis however, levonorgestrel containing IUDs are more
Combined oral contraceptive pill
Combined_oral_contraceptive_pill
Protein-coding gene in the species Homo sapiens
aorta ascending aorta spinal ganglia periodontal fiber body of uterus myometrium left coronary artery trigeminal ganglion Top expressed in endothelial
Galectin-1
Any steroid hormone that promotes male characteristics
isolation on AHN. Androgens have potential roles in relaxation of the myometrium via non-genomic, androgen receptor-independent pathways, preventing premature
Androgen
Protein-coding gene in the species Homo sapiens
Human Mouse (ortholog) Top expressed in liver right lobe of liver vagina myometrium sural nerve stromal cell of endometrium canal of the cervix right lung
CYP2A7
Medical condition
Other Metropathia haemorrhagica Female infertility Recurrent miscarriage Myometrium Adenomyosis Uterine fibroid Parametrium Parametritis Cervix Cervical cancer
Endometrioma
Protein-coding gene in humans
HS (July 2001). "HOXA10 expression is repressed by progesterone in the myometrium: differential tissue-specific regulation of HOX gene expression in the
Homeobox_A10
Protein-coding gene in the species Homo sapiens
skeletal muscle tissue sural nerve right coronary artery granulocyte myometrium body of uterus subcutaneous adipose tissue canal of the cervix Top expressed
RASA4
Protein-coding gene in the species Homo sapiens
ventricle tail of epididymis hair follicle visceral pleura seminal vesicula myometrium right coronary artery popliteal artery tibial arteries Top expressed in
Palladin
Chemical compound used as an antihemorrhagic
"Etamsylate as inhibitor of prostaglandin biosynthesis in pregnant human myometrium in vitro". Experientia. 37 (11): 1182–1183. doi:10.1007/BF01989908. PMID 7319004
Etamsylate
Immature ovum or egg cell
Internal os External os Supravaginal portion Horns Layers Wall Endometrium Myometrium Perimetrium Parametrium Epithelium Ligaments Round ligaments Broad ligaments
Oocyte
Protein that stimulates red blood cell production
pancreas canal of the cervix ectocervix muscle tissue body of uterus myometrium seminal vesicula mouth human kidney Top expressed in embryo vasculature
Erythropoietin
Protein-coding gene in humans
metanephric glomerulus saphenous vein right ventricle tail of epididymis myometrium Top expressed in spermatocyte condyle tibiofemoral joint tunica media
CDC42EP3
Enzyme in humans
tissue cartilage tissue gallbladder decidua Descending thoracic aorta myometrium tendon of biceps brachii Top expressed in body of femur vestibular membrane
Fibroblast activation protein, alpha
Fibroblast_activation_protein,_alpha
Protein-coding gene in humans
saphenous vein urethra tibia vena cava myocardium of left ventricle embryo myometrium trigeminal ganglion Top expressed in hand vas deferens lumbar spinal ganglion
FBXL7
Protein-coding gene in the species Homo sapiens
central medial nuclei); intestinal mucosal epithelia at the apex of crypts; myometrium (stromal cells, endothelial cells, and, in pregnancy, placenta, chorion
Prostaglandin_EP3_receptor
Non-coding RNA in the species Homo sapiens
zone of nasal mucosa ectocervix body of pancreas skeletal muscle tissue myometrium left ovary monocyte n/a More reference expression data BioGPS n/a Orthologs
MicroRNA_499a
Protein family and hormone
humans, prolactin is produced at least in the anterior pituitary, decidua, myometrium, breast, lymphocytes, leukocytes and prostate. Pituitary prolactin is
Prolactin
Part of the vulva that covers and protects the glans of the clitoris
Internal os External os Supravaginal portion Horns Layers Wall Endometrium Myometrium Perimetrium Parametrium Epithelium Ligaments Round ligaments Broad ligaments
Clitoral_hood
Protein-coding gene in the species Homo sapiens
"Up-regulation in late pregnancy of both Go1 alpha and Go2 alpha isoforms in human myometrium". Eur. J. Pharmacol. 288 (1): 9–15. doi:10.1016/0922-4106(94)90004-3.
GNAO1
via copulation. Histologically, the pregnant sow suffers lesions in the myometrium due to the infiltration of monocytes. The fetus presents: retarded growth
SMEDI
Protein-coding gene in the species Homo sapiens
muscle tissue muscle layer of sigmoid colon sural nerve body of uterus myometrium caudate nucleus n/a More reference expression data BioGPS n/a Gene ontology
DCHS2
Medical condition
both the uterine and the ovarian arteries. Surrounded by uterine muscle (myometrium) it can expand significantly when it hosts a pregnancy. Interstitial pregnancies
Interstitial_pregnancy
Protein-coding gene in humans
artery muscle layer of sigmoid colon Descending thoracic aorta nipple myometrium smooth muscle tissue Top expressed in retinal pigment epithelium pyloric
Testin
Development and formation of the human embryo
is termed the decidua basalis; it lies between the blastocyst and the myometrium and forms the maternal part of the placenta. The implantation is assisted
Human_embryonic_development
Protein-coding gene in the species Homo sapiens
upper lobe of left lung C1 segment smooth muscle tissue body of uterus myometrium Top expressed in molar body of femur fossa calvaria lobe of cerebellum
PHEX
Protein-coding gene in the species Homo sapiens
cerebellum stromal cell of endometrium granulocyte body of uterus right ovary myometrium left ovary Top expressed in external carotid artery internal carotid artery
LZTR1
Species of plant
of the main effects is the inhibition of contractile activity in the myometrium and death by kidney failure. The studies also found that long-term exposure
Mentha_pulegium
Expanded region of the vaginal canal at the internal end of the vagina
Internal os External os Supravaginal portion Horns Layers Wall Endometrium Myometrium Perimetrium Parametrium Epithelium Ligaments Round ligaments Broad ligaments
Vaginal_vault
Gram stain scoring system for vaginal swabs to diagnose bacterial vaginosis
Other Metropathia haemorrhagica Female infertility Recurrent miscarriage Myometrium Adenomyosis Uterine fibroid Parametrium Parametritis Cervix Cervical cancer
Nugent_score
Protein
gastric mucosa gallbladder body of uterus left coronary artery tibia myometrium Top expressed in gastrula saccule decidua sciatic nerve vas deferens intercostal
SMOC2
Protrusion of the bladder into the vagina
Other Metropathia haemorrhagica Female infertility Recurrent miscarriage Myometrium Adenomyosis Uterine fibroid Parametrium Parametritis Cervix Cervical cancer
Cystocele
Pregnancy through in vivo fertilization
prostaglandins. (Prostaglandins are also the compounds responsible for causing the myometrium to contract and expel the menses from the uterus, during menstruation
Artificial_insemination
Protein-coding gene in humans
fibroblasts during interstitial fibrosis. In adults, it is highly expressed in myometrium with lower levels in adrenal gland and fallopian tube. It is highly expressed
Angiotensin II receptor type 2
Angiotensin_II_receptor_type_2
Medication used for preventing postpartum bleeding
functions as an agonist at peripheral oxytocin receptors, particularly in the myometrium, with lesser affinity for myoepithelial cells. Oxytocin receptors are
Carbetocin
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