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Parent compound of opioids
Morphinan is the prototype chemical structure of a large chemical class of psychoactive drugs, consisting of opiate analgesics, cough suppressants, and
Morphinan
Cough suppressant and dissociative drug
antidepressant in people with major depressive disorder. It is in the morphinan class of medications with dissociative and stimulant properties (at lower
Dextromethorphan
Opioid analgesic
semisynthetic mixed agonist/antagonist opioid modulator of the phenanthrene or morphinan series. It is structurally related to the widely used opioid antagonists
Nalbuphine
Opioid analgesic
Butorphanol is a morphinan-type synthetic agonist–antagonist opioid analgesic developed by Bristol-Myers. Butorphanol is most closely structurally related
Butorphanol
Class of psychoactive drugs
dissociatives include arylcyclohexylamines like ketamine and phencyclidine (PCP); morphinans like dextromethorphan (DXM); inhalants like nitrous oxide (N2O); diarylethylamines
Dissociative
Opioid medication used for pain relief
dihydromorphinone, and sold under the brand name Dilaudid among others, is a morphinan opioid used to treat moderate to severe pain. Typically, long-term use
Hydromorphone
Chemical compound
3-Hydroxymorphinan (3-HM), or morphinan-3-ol, is a psychoactive drug of the morphinan family. It is the racemic counterpart to norlevorphanol. The dextrorotatory
3-Hydroxymorphinan
Canadian federal drug regulation act
acetate) Benzylmorphine (7,8-didehydro-4,5-epoxy-17-methyl-3-(phenylmethoxy) morphinan-6-ol) Codoxime (dihydrocodeinone O-(carboxymethyl) oxime) Desomorphine
Controlled Drugs and Substances Act
Controlled_Drugs_and_Substances_Act
Psychoactive cough suppressant medication
Dextrorphan (DXO) is a psychoactive drug of the morphinan class which acts as an antitussive or cough suppressant and in high doses a dissociative hallucinogen
Dextrorphan
Species of plant
Benzimidazoles Nitazenes Fentanyl analogues/phenylpiperidines Mitragyna alkaloids Morphinans/phenanthrenes Opiates/opium alkaloids Utopioids Antihistamines/H1 receptor
Mitragyna_speciosa
Psychoactive chemical
(March 2012). "Crystal structure of the µ-opioid receptor bound to a morphinan antagonist". Nature. 485 (7398): 321–6. Bibcode:2012Natur.485..321M. doi:10
Opioid
Polycyclic aromatic hydrocarbon composed of three fused benzene rings
byproducts of coal coking, since it makes around 4–6% of coke oven coal tar. Morphinan is the chemical structure found in several psychoactive drugs, consisting
Phenanthrene
Chemical compound
Ro4-1539 (furethylnorlevorphanol) is an opioid analgesic drug from the morphinan series that was discovered by the pharmaceutical company Hoffmann–La Roche
Ro4-1539
Tropane alkaloid and stimulant drug
Benzimidazoles Nitazenes Fentanyl analogues/phenylpiperidines Mitragyna alkaloids Morphinans/phenanthrenes Opiates/opium alkaloids Utopioids Antihistamines/H1 receptor
Cocaine
Other morphinans 4-chlorophenylpyridomorphinan Cyclorphan Dextrallorphan Levargorphan Levophenacylmorphan Levomethorphan Norlevorphanol N-Methylmorphinan
List_of_opioids
Opioid analgesic and recreational drug
also known as diacetylmorphine and diamorphine among other names, is a morphinan opioid substance synthesized from the dried latex of the opium poppy;
Heroin
Opioid analgesic drug
effects. Chemically, levorphanol belongs to the morphinan class and is (−)-3-hydroxy-N-methyl-morphinan. It is the "left-handed" (levorotatory) stereoisomer
Levorphanol
Chemical compound
diverse range of alkaloids including papaverine and stylopine, the route to morphinan alkaloids proceeds solely via its enantiomer, (R)-reticuline. This is
Reticuline
Chemical compound
2,4-Dinitrophenylmorphine is an analog of morphine in which a hydroxyl group is substituted with a dinitro phenoxy group. Being an analog of morphine,
2,4-Dinitrophenylmorphine
Species of flowering plant in the poppy family
points, since from (S) -reticuline morphine can be formed through the morphinan route, noscapine through the path of the noscapina or berberina. The poppy
Papaver_somniferum
Central nervous system stimulant
Benzimidazoles Nitazenes Fentanyl analogues/phenylpiperidines Mitragyna alkaloids Morphinans/phenanthrenes Opiates/opium alkaloids Utopioids Antihistamines/H1 receptor
Amphetamine
Species of plant
amantadine) Diarylethylamines (e.g., diphenidine, ephenidine, methoxphenidine) Morphinans (e.g., dextromethorphan (DXM), dextrorphan (DXO)) Inhalants (e.g., nitrous
Salvia_divinorum
Opioid receptor antagonist
as 17-allyl-4,5α-epoxy-3,14-dihydroxymorphinan-6-one, is a synthetic morphinan derivative and was derived from oxymorphone (14-hydroxydihydromorphinone)
Naloxone
Opioid analgesic
Levomethorphan (LVM) (INN, BAN) is an opioid analgesic of the morphinan family that has never been marketed. It is the L-stereoisomer of racemethorphan
Levomethorphan
Chemical compound
Dextrallorphan (DXA) is a chemical of the morphinan class that is used in scientific research. It acts as a σ1 receptor agonist and NMDA receptor antagonist
Dextrallorphan
Opioid medication
opioid: 3-{2-{3-{3-benzyloxypropyl}-3-indol, 7,8-didehydro- 4,5-epoxy-3,6-d-morphinan. Thodey et al., 2014 introduce a microbial compound manufacturing system
Oxycodone
Gamma-aminobutyric acid analog
Benzimidazoles Nitazenes Fentanyl analogues/phenylpiperidines Mitragyna alkaloids Morphinans/phenanthrenes Opiates/opium alkaloids Utopioids Antihistamines/H1 receptor
Gabapentin
ketamine (K), phencyclidine (PCP), methoxetamine (MXE), and tiletamine Morphinans such as dextromethorphan (DXM), its active metabolite dextrorphan (DXO)
List_of_hallucinogens
Chemical compound
(developmental code name SBW-22), or ketorphanol, is an opioid analgesic of the morphinan family that was found to possess "potent antiwrithing activity" in animal
Ketorfanol
Pain medication of the opiate family
structure have been used to create completely synthetic drugs such as the morphinan family (levorphanol, dextromethorphan and others) and other groups that
Morphine
Chemical compound
Benzimidazoles Nitazenes Fentanyl analogues/phenylpiperidines Mitragyna alkaloids Morphinans/phenanthrenes Opiates/opium alkaloids Utopioids Antihistamines/H1 receptor
Γ-Hydroxybutyric_acid
nitazenes. Orphines are not structural analogues of morphine (known as morphinans), despite the similar name. Initially, the term referred to compounds
List_of_orphine_opioids
Pharmaceutical drug classification
ATC code N02 Analgesics is a therapeutic subgroup of the Anatomical Therapeutic Chemical Classification System, a system of alphanumeric codes developed
ATC_code_N02
Drug that increases alertness
Benzimidazoles Nitazenes Fentanyl analogues/phenylpiperidines Mitragyna alkaloids Morphinans/phenanthrenes Opiates/opium alkaloids Utopioids Antihistamines/H1 receptor
Stimulant
Class of opioid receptors found in humans
(March 2012). "Crystal structure of the μ-opioid receptor bound to a morphinan antagonist". Nature. 485 (7398): 321–326. Bibcode:2012Natur.485..321M
Mu-opioid_receptor
Dissociative anesthetic and anti-depressant
Methoxphenidine (MXP) NPDPA (isopropylphenidine, isophenidine) Remacemide Morphinans Dextrallorphan (DXA) Dextromethorphan (DXM) Dextrorphan (DXO) Racemethorphan
Ketamine
Species of plant
amantadine) Diarylethylamines (e.g., diphenidine, ephenidine, methoxphenidine) Morphinans (e.g., dextromethorphan (DXM), dextrorphan (DXO)) Inhalants (e.g., nitrous
Hyoscyamus_niger
Central nervous system stimulant
Benzimidazoles Nitazenes Fentanyl analogues/phenylpiperidines Mitragyna alkaloids Morphinans/phenanthrenes Opiates/opium alkaloids Utopioids Antihistamines/H1 receptor
Caffeine
Medication used to treat dyskinesia
Methoxphenidine (MXP) NPDPA (isopropylphenidine, isophenidine) Remacemide Morphinans Dextrallorphan (DXA) Dextromethorphan (DXM) Dextrorphan (DXO) Racemethorphan
Amantadine
Class of depressant drugs derived from barbituric acid
Benzimidazoles Nitazenes Fentanyl analogues/phenylpiperidines Mitragyna alkaloids Morphinans/phenanthrenes Opiates/opium alkaloids Utopioids Antihistamines/H1 receptor
Barbiturate
Cough suppressant drug
acting cough suppressant developed in France in the 1970s. It is not a morphinan derivative (in contrast to both codeine and dextromethorphan). Zipeprol
Zipeprol
Opioid analgesic
Cyclorphan is an opioid analgesic of the morphinan family that was never marketed. It acts as a μ-opioid receptor (MOR) weak partial agonist or antagonist
Cyclorphan
Class of psychoactive drugs
Benzimidazoles Nitazenes Fentanyl analogues/phenylpiperidines Mitragyna alkaloids Morphinans/phenanthrenes Opiates/opium alkaloids Utopioids Antihistamines/H1 receptor
Nonbenzodiazepine
Laboratory synthesis of natural chemicals
morphine-like alkaloids in chemistry describes the total synthesis of the natural morphinan class of alkaloids that includes codeine, morphine, oripavine, and thebaine
Total synthesis of morphine and related alkaloids
Total_synthesis_of_morphine_and_related_alkaloids
Anticholinergic medication used as antidote for nerve agent poisoning
amantadine) Diarylethylamines (e.g., diphenidine, ephenidine, methoxphenidine) Morphinans (e.g., dextromethorphan (DXM), dextrorphan (DXO)) Inhalants (e.g., nitrous
Atropine
Dried latex of the opium poppy containing narcotic compounds
(poppy straw) can be crushed and used to produce lower quantities of morphinans. In poppies subjected to mutagenesis and selection on a mass scale, researchers
Opium
Chemical compound
action against other types of pain seems to be limited. Sinomenine is a morphinan derivative that is related to the common cough suppressant dextromethorphan
Sinomenine
Obsolete sedative–hypnotic drug
Benzimidazoles Nitazenes Fentanyl analogues/phenylpiperidines Mitragyna alkaloids Morphinans/phenanthrenes Opiates/opium alkaloids Utopioids Antihistamines/H1 receptor
Methaqualone
Species of mushroom
amantadine) Diarylethylamines (e.g., diphenidine, ephenidine, methoxphenidine) Morphinans (e.g., dextromethorphan (DXM), dextrorphan (DXO)) Inhalants (e.g., nitrous
Amanita_muscaria
Chemical compound
where hydroxylation occurs at the carbon atom in position 14 of the morphinan skeleton. Meshulam, Haim; Lavie, David (1980-01-01). "The alkaloidal constituents
14-Hydroxycodeine
Central nervous system stimulant
Benzimidazoles Nitazenes Fentanyl analogues/phenylpiperidines Mitragyna alkaloids Morphinans/phenanthrenes Opiates/opium alkaloids Utopioids Antihistamines/H1 receptor
Methylphenidate
Vedic ritual drink
amantadine) Diarylethylamines (e.g., diphenidine, ephenidine, methoxphenidine) Morphinans (e.g., dextromethorphan (DXM), dextrorphan (DXO)) Inhalants (e.g., nitrous
Soma_(drink)
Opiate and prodrug of morphine used to treat pain
tartrate, and other salts are also seen. The chemical name for codeine is morphinan-6-ol, 7,8-didehydro-4,5-epoxy-3-methoxy-17-methyl-, (5α,6α)- A heroin
Codeine
Racemic mixture
hydrochloride (0.876), and tartrate (0.632). Levallorphan Methorphan Morphinan Cyclorphan Cough syrup Noscapine Codeine; Pholcodine Dextromethorphan;
Racemorphan
Medication used for epilepsy, bipolar disorder and migraine
Benzimidazoles Nitazenes Fentanyl analogues/phenylpiperidines Mitragyna alkaloids Morphinans/phenanthrenes Opiates/opium alkaloids Utopioids Antihistamines/H1 receptor
Valproate
Dissociative hallucinogenic drug, mostly used recreationally
Methoxphenidine (MXP) NPDPA (isopropylphenidine, isophenidine) Remacemide Morphinans Dextrallorphan (DXA) Dextromethorphan (DXM) Dextrorphan (DXO) Racemethorphan
Phencyclidine
Purported inhalant drug
amantadine) Diarylethylamines (e.g., diphenidine, ephenidine, methoxphenidine) Morphinans (e.g., dextromethorphan (DXM), dextrorphan (DXO)) Inhalants (e.g., nitrous
Jenkem
Species of orchid
namely 3-{2-{3-{3-(benzyloxy)propyl}-3-indol-7,8-didehydro-4,5-epoxy-3,6-D-morphinan and oxycodone. "Epipactis helleborine (L.) Crantz". Plants of the World
Epipactis_helleborine
Substance that arouses sexual desires
Benzimidazoles Nitazenes Fentanyl analogues/phenylpiperidines Mitragyna alkaloids Morphinans/phenanthrenes Opiates/opium alkaloids Utopioids Antihistamines/H1 receptor
Aphrodisiac
Antihistamine medication
amantadine) Diarylethylamines (e.g., diphenidine, ephenidine, methoxphenidine) Morphinans (e.g., dextromethorphan (DXM), dextrorphan (DXO)) Inhalants (e.g., nitrous
Diphenhydramine
Class of anesthetics
Methoxphenidine (MXP) NPDPA (isopropylphenidine, isophenidine) Remacemide Morphinans Dextrallorphan (DXA) Dextromethorphan (DXM) Dextrorphan (DXO) Racemethorphan
NMDA_receptor_antagonist
Transnational drug-trafficking organization
phenylpiperidine in its molecular structure, unlike the more traditional morphinan poppy-derived opiates such as codeine, morphine and even the closely related
Sinaloa_Cartel
Genus of flowering plants in the nightshade family
amantadine) Diarylethylamines (e.g., diphenidine, ephenidine, methoxphenidine) Morphinans (e.g., dextromethorphan (DXM), dextrorphan (DXO)) Inhalants (e.g., nitrous
Brugmansia
Chemical stimulant produced by some plants
Benzimidazoles Nitazenes Fentanyl analogues/phenylpiperidines Mitragyna alkaloids Morphinans/phenanthrenes Opiates/opium alkaloids Utopioids Antihistamines/H1 receptor
Nicotine
Class of medications
Benzimidazoles Nitazenes Fentanyl analogues/phenylpiperidines Mitragyna alkaloids Morphinans/phenanthrenes Opiates/opium alkaloids Utopioids Antihistamines/H1 receptor
Anticonvulsant
Chemical compound
Benzimidazoles Nitazenes Fentanyl analogues/phenylpiperidines Mitragyna alkaloids Morphinans/phenanthrenes Opiates/opium alkaloids Utopioids Antihistamines/H1 receptor
Phenylpiracetam
Class of CNS depressant drugs
Benzimidazoles Nitazenes Fentanyl analogues/phenylpiperidines Mitragyna alkaloids Morphinans/phenanthrenes Opiates/opium alkaloids Utopioids Antihistamines/H1 receptor
Benzodiazepine
Chemical compound
14-Endoethenotetrahydrooripavine is the central nucleus, or backbone, of a class of morphinan opioids known as the Bentley compounds and may be considered their "privileged
6,14-Endoethenotetrahydrooripavine
6,14-Endoethenotetrahydrooripavine
Molecule with three connected cyclohexane rings arranged in the "armchair" configuration
Benzimidazoles Nitazenes Fentanyl analogues/phenylpiperidines Mitragyna alkaloids Morphinans/phenanthrenes Opiates/opium alkaloids Utopioids Antihistamines/H1 receptor
Adamantane
Species of plant
amantadine) Diarylethylamines (e.g., diphenidine, ephenidine, methoxphenidine) Morphinans (e.g., dextromethorphan (DXM), dextrorphan (DXO)) Inhalants (e.g., nitrous
Tabernanthe_iboga
Chemical compound
amantadine) Diarylethylamines (e.g., diphenidine, ephenidine, methoxphenidine) Morphinans (e.g., dextromethorphan (DXM), dextrorphan (DXO)) Inhalants (e.g., nitrous
Adrenochrome
Chemical compound
collectively as hasubanans. The compound is derived from reticuline, as is morphinan, but is comparatively more oxidized and rearranged. It is similar to acutumine
Hasubanan
Species of fungus
amantadine) Diarylethylamines (e.g., diphenidine, ephenidine, methoxphenidine) Morphinans (e.g., dextromethorphan (DXM), dextrorphan (DXO)) Inhalants (e.g., nitrous
Lanmaoa_asiatica
Group of stereoisomers
hydrobromide (free base conversion ratio 0.770) and the tartrate (0.644). Morphinan Racemorphan Anvisa (31 March 2023). "RDC Nº 784 - Listas de Substâncias
Methorphan
Chemical compound
more potent than morphine, and a similar strength to the closely related morphinan derivative phenomorphan. 14-Cinnamoyloxycodeinone 14-Phenylpropoxymetopon
N-Phenethylnordesomorphine
Chemical compound
Benzimidazoles Nitazenes Fentanyl analogues/phenylpiperidines Mitragyna alkaloids Morphinans/phenanthrenes Opiates/opium alkaloids Utopioids Antihistamines/H1 receptor
Dibenzosuberone
Class of medications used to alleviate anxiety
Benzimidazoles Nitazenes Fentanyl analogues/phenylpiperidines Mitragyna alkaloids Morphinans/phenanthrenes Opiates/opium alkaloids Utopioids Antihistamines/H1 receptor
Anxiolytic
Drug that produces a dream-like state of consciousness
amantadine) Diarylethylamines (e.g., diphenidine, ephenidine, methoxphenidine) Morphinans (e.g., dextromethorphan (DXM), dextrorphan (DXO)) Inhalants (e.g., nitrous
Oneirogen
First-generation antihistamine used as a short-term sedative and hypnotic (sleep aid)
amantadine) Diarylethylamines (e.g., diphenidine, ephenidine, methoxphenidine) Morphinans (e.g., dextromethorphan (DXM), dextrorphan (DXO)) Inhalants (e.g., nitrous
Doxylamine
Botched execution in Arizona (2014)
with a combination of midazolam, a benzodiazepine, and hydromorphone, a morphinan opioid, a combination which had been used only once previously for the
Execution_of_Joseph_Wood
Monoamine neurotransmitter
Benzimidazoles Nitazenes Fentanyl analogues/phenylpiperidines Mitragyna alkaloids Morphinans/phenanthrenes Opiates/opium alkaloids Utopioids Antihistamines/H1 receptor
Serotonin
Psychoactive substance found in plants in the family Apocynaceae
amantadine) Diarylethylamines (e.g., diphenidine, ephenidine, methoxphenidine) Morphinans (e.g., dextromethorphan (DXM), dextrorphan (DXO)) Inhalants (e.g., nitrous
Ibogaine
Drug that reduces excitement without inducing sleep
Benzimidazoles Nitazenes Fentanyl analogues/phenylpiperidines Mitragyna alkaloids Morphinans/phenanthrenes Opiates/opium alkaloids Utopioids Antihistamines/H1 receptor
Sedative
Chemical compound
as a potential painkiller. Hasubanonine is structurally related to the morphinan class of opioid analgesics. The enantioselective total synthesis of (–)-hasubanonine
Hasubanonine
Class of chemical compounds
Benzimidazoles Nitazenes Fentanyl analogues/phenylpiperidines Mitragyna alkaloids Morphinans/phenanthrenes Opiates/opium alkaloids Utopioids Antihistamines/H1 receptor
Catecholamine
(21 March 2012). "Crystal structure of the μ-opioid receptor bound to a morphinan antagonist". Nature. 485 (7398): 321–326. Bibcode:2012Natur.485..321M
List of drugs by year of discovery
List_of_drugs_by_year_of_discovery
Colourless non-flammable greenhouse gas
Methoxphenidine (MXP) NPDPA (isopropylphenidine, isophenidine) Remacemide Morphinans Dextrallorphan (DXA) Dextromethorphan (DXM) Dextrorphan (DXO) Racemethorphan
Nitrous_oxide
Chemical element with atomic number 54 (Xe)
Methoxphenidine (MXP) NPDPA (isopropylphenidine, isophenidine) Remacemide Morphinans Dextrallorphan (DXA) Dextromethorphan (DXM) Dextrorphan (DXO) Racemethorphan
Xenon
Class of drugs
amantadine) Diarylethylamines (e.g., diphenidine, ephenidine, methoxphenidine) Morphinans (e.g., dextromethorphan (DXM), dextrorphan (DXO)) Inhalants (e.g., nitrous
Hallucinogen
Spice from Myristica fragrans
amantadine) Diarylethylamines (e.g., diphenidine, ephenidine, methoxphenidine) Morphinans (e.g., dextromethorphan (DXM), dextrorphan (DXO)) Inhalants (e.g., nitrous
Nutmeg
Class of compounds based upon the amphetamine structure
Benzimidazoles Nitazenes Fentanyl analogues/phenylpiperidines Mitragyna alkaloids Morphinans/phenanthrenes Opiates/opium alkaloids Utopioids Antihistamines/H1 receptor
Substituted_amphetamine
Class of psychoactive drugs
amantadine) Diarylethylamines (e.g., diphenidine, ephenidine, methoxphenidine) Morphinans (e.g., dextromethorphan (DXM), dextrorphan (DXO)) Inhalants (e.g., nitrous
Deliriant
Parasympathetic nervous system inhibitors
Kim, Hyoung-Chun; Nah, Seung-Yeol (2006). "Effects of dextrorotatory morphinans on α3β4 nicotinic acetylcholine receptors expressed in Xenopus oocytes"
Anticholinergic
Plant species in the family
amantadine) Diarylethylamines (e.g., diphenidine, ephenidine, methoxphenidine) Morphinans (e.g., dextromethorphan (DXM), dextrorphan (DXO)) Inhalants (e.g., nitrous
Peganum_harmala
Antihistamine medication
amantadine) Diarylethylamines (e.g., diphenidine, ephenidine, methoxphenidine) Morphinans (e.g., dextromethorphan (DXM), dextrorphan (DXO)) Inhalants (e.g., nitrous
Triprolidine
Organic compound, a stimulant in humans
Benzimidazoles Nitazenes Fentanyl analogues/phenylpiperidines Mitragyna alkaloids Morphinans/phenanthrenes Opiates/opium alkaloids Utopioids Antihistamines/H1 receptor
Phenethylamine
Chemical compound
Tubocurarine (composed of two benzylisoquinoline units) Aminosteroid Gallamine Morphinan Indole Indolizidine Stadler, Richard; Kutchan, Toni M; Zenk, Meinhart
Benzylisoquinoline
Tropane alkaloid & anticholinergic drug
amantadine) Diarylethylamines (e.g., diphenidine, ephenidine, methoxphenidine) Morphinans (e.g., dextromethorphan (DXM), dextrorphan (DXO)) Inhalants (e.g., nitrous
Scopolamine
Chemical compound
code name BL-5572M), is an opioid analgesic and antitussive drug of the morphinan family that was never marketed. It acts preferentially as a κ-opioid receptor
Proxorphan
Carbamate derivative used as an anti-anxiety medication
Benzimidazoles Nitazenes Fentanyl analogues/phenylpiperidines Mitragyna alkaloids Morphinans/phenanthrenes Opiates/opium alkaloids Utopioids Antihistamines/H1 receptor
Meprobamate
MORPHINAN
MORPHINAN
MORPHINAN
MORPHINAN
Boy/Male
Greek
Uncle of Oedipus.
Girl/Female
Hindu, Indian, Sanskrit, Telugu
Wonderful
Boy/Male
Indian
Pure
Girl/Female
Indian
Firm, Fortress, A buddhist Goddess
Girl/Female
British, English
Court-dweller
Male
Spanish
Portuguese and Spanish form of Latin Petrus, PEDRO means "rock, stone."
Surname or Lastname
English
English : from an unattested Old English personal name Eoforīc, composed of the elements eofor ‘wild boar’ + rīc ‘rich’.
Female
Persian/Iranian
Persian name GHONCHEH means "flower bud."
Female
Turkish
Turkish name GIZEM means "mystery."
Boy/Male
Arabic, Muslim, Sindhi
Heavenly Fountain
MORPHINAN
MORPHINAN
MORPHINAN
MORPHINAN
MORPHINAN