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Cough suppressant and dissociative drug
Dextromethorphan is a cough suppressant used in many cough and cold medicines. In 2022, the US Food and Drug Administration (FDA) approved the combination
Dextromethorphan
Combination medication
Dextromethorphan/bupropion, sold under the brand name Auvelity, is a combination medication for the treatment of major depressive disorder (MDD) and agitation
Dextromethorphan/bupropion
Opioid-based cough suppressant regulation in the US
Dextromethorphan is a cough suppressant found in several cold medications. Several U.S. states have begun regulating who, and under what circumstances
Dextromethorphan regulation by U.S. jurisdiction
Dextromethorphan_regulation_by_U.S._jurisdiction
Cough suppressant drug susceptible to misuse
Dextromethorphan, or DXM, a common active ingredient found in many over-the-counter cough suppressant cold medicines, is used as a recreational drug and
Recreational use of dextromethorphan
Recreational_use_of_dextromethorphan
Pharmaceutical drug
Dextromethorphan/quinidine, sold under the brand name Nuedexta, is a fixed-dose combination medication for the treatment of pseudobulbar affect (PBA).
Dextromethorphan/quinidine
Sedating antihistamine
Flukit; with dextromethorphan as Axcel Dextrozine and Hosedyl DM; with dextromethorphan and ephedrine as Methorsedyl; with dextromethorphan and pseudoephedrine
Promethazine
Psychoactive cough suppressant medication
O-demethylation of dextromethorphan by CYP2D6. Dextrorphan is an NMDA antagonist and contributes to the psychoactive effects of dextromethorphan. The pharmacology
Dextrorphan
Expectorant medication
States, with more than 500,000 prescriptions. In 2023, the combination dextromethorphan/guaifenesin was the 315th most commonly prescribed medication in the
Guaifenesin
Medication mainly used for depression and smoking cessation
the US Food and Drug Administration (FDA) approved the combination dextromethorphan/bupropion to serve as a rapid-acting antidepressant in patients with
Bupropion
Brand of medication
contains: Acetaminophen (650 mg/30 mL) (pain reliever/fever reducer) Dextromethorphan (30 mg/30 mL) (cough suppressant) Doxylamine succinate (12.5 mg/30 mL)
NyQuil
Class of anesthetics
and ketobemidone. Some NMDA receptor antagonists, such as ketamine, dextromethorphan (DXM), phencyclidine (PCP), methoxetamine (MXE), and nitrous oxide
NMDA_receptor_antagonist
Medication product
resolution outcomes versus no treatment. Abuse and recreational use of dextromethorphan have been reported with over-the-counter preparations and can cause
DayQuil
Chemical compound
3-Methoxymorphinan is an inactive metabolite of both dextromethorphan and levomethorphan, and has been shown to produce local anesthetic effects. It is
3-Methoxymorphinan
Class of psychoactive drugs
arylcyclohexylamines like ketamine and phencyclidine (PCP); morphinans like dextromethorphan (DXM); inhalants like nitrous oxide (N2O); diarylethylamines like diphenidine
Dissociative
Sudden expulsion of air from the lungs as a reflex to clear irritants
discontinuing ACE inhibitors. Cough suppressants such as codeine or dextromethorphan are frequently prescribed, but are not recommended for children. Other
Cough
Parent compound of opioids
Typical examples include compounds such as morphine, codeine, and dextromethorphan (DXM). Despite related molecular structures, the pharmacological profiles
Morphinan
Brand name for a cough and pain medicine
of an over-the-counter cough and cold combination drug containing dextromethorphan (a cough suppressant) and chlorpheniramine maleate (a first-generation
Coricidin
American online streamer (born 2005)
and was hospitalized; he had been using a combination of Adderall, dextromethorphan, pregabalin, ketamine and 1,4-Butanediol, referred to as the "pentastack"
Clavicular_(influencer)
Gerdaxy) Serotonin–norepinephrine–dopamine reuptake inhibitors include: Dextromethorphan/bupropion (Auvelity) Toludesvenlafaxine (Ruoxinlin) Nefazodone (Serzone)
List_of_antidepressants
Medicated tablet to be dissolved in the mouth
(mild antiseptic) or 4-Hexylresorcinol (anaesthetic, antiseptic) or dextromethorphan (cough suppressant). Many varieties such as Halls contain menthol,
Throat_lozenge
antipsychotic (non-selective monoamine receptor modulator) Bupropion/dextromethorphan (AXS-05; Auvelity) – sigma σ1 receptor agonist, serotonin reuptake
List of investigational agitation drugs
List_of_investigational_agitation_drugs
SSRI antidepressant
antidepressant may lead to reduced analgesia. In some cases, use of dextromethorphan-containing cold and cough medications with fluoxetine is advised against
Fluoxetine
Medication taken to relieve cold symptoms
suppressants, are substances which suppress the coughing itself. Examples are dextromethorphan, benzonatate, codeine, hydrocodone, pholcodine, noscapine, cloperastine
Cold_medicine
Cough suppressant
to the cough center in the medulla oblongata, more specifically the dextromethorphan-binding site in guinea pig brain with high affinity. As a
Butamirate
Georgian metal band
and the number four referring to the four plateaus experienced using dextromethorphan. The band's lyrics are typically in Georgian, Russian, and English
Psychonaut_4
Parasympathetic nervous system inhibitors
Tropicamide Umeclidinium Antinicotinic agents Bupropion – Ganglion blocker Dextromethorphan - Cough suppressant and ganglion blocker Doxacurium – Nondepolarizing
Anticholinergic
Cough suppressant
somnolence, dry mouth, and decreased appetite. Dimemorfan is an analogue of dextromethorphan (DXM) and its active metabolite dextrorphan (DXO), and similarly to
Dimemorfan
Class of drug
Additionally, some clinically used drugs such as chlorpheniramine, dextromethorphan, and methadone possess SRI properties secondarily to their primary
Serotonin_reuptake_inhibitor
Chemical compound
1948 and came into medical use in 1955. In 2023, the combination with dextromethorphan and pseudoephedrine was the 281st most commonly prescribed medication
Brompheniramine
Psychoactive drug, often called ecstasy
Dehydroepiandrosterone sulfate (DHEA-S) (prasterone sulfate) Dextrallorphan Dextromethorphan (DXM) Dextrorphan (DXO) Dimemorfan Dimethyltryptamine (DMT) Ditolylguanidine
MDMA
Chemical compound
dextrorotatory stereoisomer of the compound is an active metabolite of dextromethorphan, dextrorphan, and 3-methoxymorphinan, and similarly to them has potent
3-Hydroxymorphinan
Medication used to treat epilepsy and migraine
topiramate in the management of cravings related to withdrawal from dextromethorphan. A 2023 systematic review of seizure treatment for infants aged 1 to
Topiramate
Type of medication
brompheniramine, MDMA, meperidine, tramadol, methadone, tapentadol, dextromethorphan, dextropropoxyphene, pentazocine, and levorphanol. The main risk is
Monoamine_oxidase_inhibitor
Recreational drug beverage
hydrocodone/homatropine. Over-the-counter cold medicines that contain dextromethorphan (often paired with guaifenasin or acetaminophen) as the active ingredient
Lean_(drug)
Cough syrup crisis in India
government-distributed cough syrup containing the active ingredient dextromethorphan hydrobromide made by Kayson Pharma. The World Health Organization also
2025_India_cough_syrup_crisis
First-generation antihistamine used as a short-term sedative and hypnotic (sleep aid)
(contains acetaminophen, doxylamine succinate 6.25 to 12.5 mg, and dextromethorphan hydrobromide), where it serves as the sedating component. The fetal
Doxylamine
Drug used to treat anxiety disorders
treatment of agitation, both alone (as EXV-801) and in combination with dextromethorphan (DXM) (as EXV-802). The drug acts as a serotonin 5-HT2A receptor antagonist
Deramciclane
Medication
under the Tylenol brand. These can include codeine as co-codamol, dextromethorphan, methocarbamol, guaifenesin, pseudoephedrine, caffeine, diphenhydramine
Tylenol
Class of antidepressant medication
antidepressants. Atypical antidepressants include: agomelatine bupropion dextromethorphan/bupropion esketamine gepirone iprindole opipramol tianeptine maprotiline
Atypical_antidepressant
Brand of medication
Variants were created, including Dimetapp DM with the addition of dextromethorphan (an antitussive or cough suppressant). Dimetapp Elixir and Colour Free
Dimetapp
Excessive drug dosing
opioid addiction can play a role in prevention and early intervention. Dextromethorphan, also shortened to DXM, affects the NMDA receptor and serotonin receptors
Overmedication
Chemical compound
such use, it is less effective than codeine and more effective than dextromethorphan in inhibiting the tussive stimulus. [1] Archived 2019-08-17 at the
Nepinalone
Pain affecting the somatosensory nervous system
role in neuropathic pain and in the development of opioid tolerance. Dextromethorphan is an NMDA antagonist at high doses. Experiments in both animals and
Neuropathic_pain
Episodes of uncontrollable crying or laughing
following: placebo (N=109) dextromethorphan hydrobromide 30 mg/quinidine sulfate 10 mg (N=110) Nuedexta – dextromethorphan hydrobromide 20 mg/quinidine
Pseudobulbar_affect
Brand of various antihistamine medications
New Zealand containing diphenhydramine, as well as the antitussive dextromethorphan or the expectorant guaifenesin. There are many different forms of Benadryl
Benadryl
Neurological and psychiatric drug
CTP-786) is a combination of deudextromethorphan (d-DXM; deuterated (d6) dextromethorphan (DXM)) and quinidine (Q) which is under development by Avanir Pharmaceuticals
Deudextromethorphan/quinidine
Irreversible non-selective MAO inhibitor and antidepressant drug
certain analgesics such as meperidine, tramadol, methadone, tapentadol, dextromethorphan, dextropropoxyphene, pentazocine, and levorphanol. Concomitant use
Phenelzine
Class of medication used to treat depression and other conditions
The combination medication dextromethorphan/bupropion (Auvelity), which contains the NMDA receptor antagonist dextromethorphan, was approved in the United
Antidepressant
Group of stereoisomers
two isomeric forms, each with differing pharmacology and effects: Dextromethorphan – An over-the-counter cough suppressant, as well as dissociative hallucinogen
Methorphan
Chemical compound
use of Coricidin for the dissociative (hallucinogenic) effect of its dextromethorphan is hazardous because it also contains chlorpheniramine.[citation needed]
Pheniramine
Semi-synthetic opioid
Solution-ACE. Dihydrocodeine is used as an antitussive in many products as a Dextromethorphan alternative. Medicines in Japan which contain dihydrocodeine are coupled
Dihydrocodeine
Symptoms caused by an excess of serotonin in the central nervous system
antidepressants (TCAs), amphetamines, pethidine (meperidine), tramadol, dextromethorphan, buspirone, L-tryptophan, 5-hydroxytryptophan, St. John's wort, triptans
Serotonin_syndrome
Inability to control facial movements
approach utilizing dextromethorphan and quinidine sulfate. Nuedexta is an FDA approved medication for pseudobulbar affect. Dextromethorphan, an N-methyl-D-aspartate
Pseudobulbar_palsy
Cough medicine formulated in Massachusetts
Today, as sold, the active ingredient in Father John's Medicine is dextromethorphan hydrobromide. Many of Father John's Medicine Company Records are housed
Father_John's_Medicine
SSRI antidepressant
should be taken with caution when using St. John's wort, ginseng, dextromethorphan, linezolid, tramadol, and other serotonergic drugs due to the risk
Escitalopram
Rare neurodegenerative disease
symptoms of FTD. Pseudobulbar affect can be treated with Nuedexta (dextromethorphan/quinidine), though this relatively new compound is not available in
ALS
Class of antidepressant medication
selegiline and methylene blue Lithium Sibutramine MDMA (ecstasy) Dextromethorphan Tramadol 5-HTP Pethidine/meperidine St. John's wort Yohimbe Tricyclic
Selective serotonin reuptake inhibitor
Selective_serotonin_reuptake_inhibitor
Chemical compound
"The unexpected identification of the cannabimimetic, 5F-ADB, and dextromethorphan in commercially available cannabidiol e-liquids". Forensic Science
5F-ADB
Brand of medications
marketed in several countries as Benylin DM, for its active ingredient, dextromethorphan. However, the range of products available in both solid dosage and
Benylin
Synthetic decongestant
000 prescriptions. In 2023, the combination with brompheniramine and dextromethorphan was the 281st most commonly prescribed medication in the United States
Pseudoephedrine
Neurotoxicity caused by some NMDA receptor antagonists
a higher incidence of necrotic (dead) neurons as a result of NAT. Dextromethorphan, a common antitussive often found in cough medicines, has been shown
Olney's_lesions
Topics referred to by the same term
Dextrorphan, a psychoactive drug and metabolite of the cough suppressant dextromethorphan DxO Labs, a French photography software company DOM3Z, a gene also
Dxo
SSRI antidepressant
is contraindicated with other medications that increase serotonin (dextromethorphan, ondansetron, amphetamine, sumatriptan, Tramadol, Hypericum perforatum
Fluvoxamine
Drug for chronic pain
potassium channel-specific: Barium Caramiphen Cloperastine Clozapine Dextromethorphan Ethosuximide Ifenprodil Tertiapin Tipepidine Activators KATPTooltip
Crisugabalin
Chemical compound
(isopropylphenidine, isophenidine) Remacemide Morphinans Dextrallorphan (DXA) Dextromethorphan (DXM) Dextrorphan (DXO) Racemethorphan (methorphan) Racemorphan (morphanol)
3-Chloro-PCP
Chronic multi-symptomatic pain disorder
dronabinol, nabilone) NMDA receptor antagonists (e.g., ketamine, dextromethorphan, methadone) Opioids (e.g., hydrocodone, morphine, oxycodone, methadone
Fibromyalgia
Mental condition attributed to substance intoxication
been associated with psychosis. Over-the-counter drugs, including: Dextromethorphan (DXM) at high doses. Certain antihistamines at high doses. Cold medications
Substance-induced_psychosis
Opioid analgesic drug
active opioid. DXO is an active metabolite of the pharmaceutical drug dextromethorphan (DXM), which, analogously to DXO, is an enantiomer of the racemic mixture
Levorphanol
Drug used to treat depressive and anxiety disorders
also included haloperidol, pentazocine, (+)-3-PPP, ditolylguanidine, dextromethorphan, SKF-10,047 ((±)-alazocine), ifenprodil, progesterone, and others,
Opipramol
Irreversible non-selective MAO inhibitor and antidepressant drug
clomipramine, imipramine, tramadol, tapentadol, methadone, meperidine, dextromethorphan, dextropropoxyphene, pentazocine, levorphanol, and MDMA. Use with another
Tranylcypromine
Positive effects that linger beyond the main effects
after the usage of dissociative drugs, such as the NMDA antagonists, dextromethorphan, ketamine, and phencyclidine.[citation needed] Afterglow occurs after
Afterglow_(drug_culture)
Class of pharmaceutical drug
(d3-vitamin A) Phase 3 Slows the dimerization rate of vitamin A AVP-786 (d6-dextromethorphan) Phase 3 Reduces formation of toxic metabolite by CYP2D6 VX-984 (novel
Deuterated_drug
SSRI antidepressant
caused increased blood levels of CYP2D6 substrates such as metoprolol, dextromethorphan, desipramine, imipramine and nortriptyline, as well as the CYP3A4/CYP2D6
Sertraline
Antihistamine used to treat allergies
drug Coricidin, chlorphenamine is combined with the cough suppressant dextromethorphan. In the drug Cêgripe, chlorphenamine is combined with the analgesic
Chlorphenamine
Use of drugs with the primary intention to alter the state of consciousness
muscimol (also found in Amanita muscaria, a GABAergic) Dissociatives dextromethorphan (DXM; Robitussin, Delsym, etc.; "Dex", "Robo", "Cough Syrup", "DXM")
Recreational_drug_use
Medical condition
to reduce plasma glycine levels and NMDA receptor antagonists, like dextromethorphan or ketamine, are used to decrease NMDA receptor stimulation which can
Glycine_encephalopathy
Unequal size of the eyes' pupils
affect the pupils include pilocarpine, cocaine, tropicamide, MDMA, dextromethorphan, and ergolines. Alkaloids present in plants of the genera Brugmansia
Anisocoria
Chemical compound
(e.g., diphenidine, ephenidine, methoxphenidine) Morphinans (e.g., dextromethorphan (DXM), dextrorphan (DXO)) Inhalants (e.g., nitrous oxide (N2O), xenon
Meclizine
Topics referred to by the same term
Chrono Trigger Robotrippin, non-medical use of the pharmaceutical dextromethorphan (DXM or Robo) Robo, an aircraft design study undertaken in the late
Robo
Species of plant
(e.g., diphenidine, ephenidine, methoxphenidine) Morphinans (e.g., dextromethorphan (DXM), dextrorphan (DXO)) Inhalants (e.g., nitrous oxide (N2O), xenon
Banisteriopsis_caapi
Chemical compound
Cyclopropane Dacuronium bromide Decamethonium Dehydronorketamine Desflurane Dextromethorphan Dextropropoxyphene Dextrorphan Diadonium DHβE Dihydrochandonium Dimethyltubocurarine
Suxamethonium_chloride
Class of drug
ketamine, methoxetamine, phencyclidine) Cyclobenzaprine Delucemine Dextromethorphan Dextrorphan Efavirenz Hypidone Medifoxamine Mesembrine Mifepristone
Serotonin–dopamine reuptake inhibitor
Serotonin–dopamine_reuptake_inhibitor
Pain medication of the opiate family
morphine may be inhibited by NMDA receptor antagonists such as ketamine, dextromethorphan, and memantine. The rotation of morphine with chemically dissimilar
Morphine
Cyclopropane Dacuronium bromide Decamethonium Dehydronorketamine Desflurane Dextromethorphan Dextropropoxyphene Dextrorphan Diadonium DHβE Dihydrochandonium Dimethyltubocurarine
Selective relaxant binding agents
Selective_relaxant_binding_agents
Pharmaceutical compound
Coronaridine Delucemine (NPS-1506) Dexoxadrol Dextrallorphan Dextromethadone Dextromethorphan Dextrorphan Dieticyclidine Diphenidine Dizocilpine Ephenidine Esketamine
RAP-219
Therapies, medications, and devices
slow the metabolism of dextromethorphan by inhibiting CYP2D6, thereby increasing its bioavailability and allowing dextromethorphan's potential antidepressant
Management_of_depression
Glutamate receptor and ion channel protein found in nerve cells
psychoactive drugs such as phencyclidine (PCP), alcohol (ethanol) and dextromethorphan (DXM). The anaesthetic and analgesic effects of the drugs ketamine
NMDA_receptor
Species of fungus
(e.g., diphenidine, ephenidine, methoxphenidine) Morphinans (e.g., dextromethorphan (DXM), dextrorphan (DXO)) Inhalants (e.g., nitrous oxide (N2O), xenon
Lanmaoa_asiatica
Type of compound
to hydrochlorides. Some drugs are formulated as hydrobromides, e.g. dextromethorphan hydrobromide. Yan, Dawei; Liu, Xiaomin; Gao, Yihan; Li, Xiaonan; Pu
Hydrobromide
Chemical compound
Cyclopropane Dacuronium bromide Decamethonium Dehydronorketamine Desflurane Dextromethorphan Dextropropoxyphene Dextrorphan Diadonium DHβE Dihydrochandonium Dimethyltubocurarine
Levamisole
Purported inhalant drug
(e.g., diphenidine, ephenidine, methoxphenidine) Morphinans (e.g., dextromethorphan (DXM), dextrorphan (DXO)) Inhalants (e.g., nitrous oxide (N2O), xenon
Jenkem
Dissociative anesthetic and anti-depressant
Cyclopropane Dacuronium bromide Decamethonium Dehydronorketamine Desflurane Dextromethorphan Dextropropoxyphene Dextrorphan Diadonium DHβE Dihydrochandonium Dimethyltubocurarine
Ketamine
Topics referred to by the same term
(ride), an amusement park ride Red Baron, a common street name of dextromethorphan Red Baron, a species of dragonfly in the genus Urothemis Red Baron
Red_Baron_(disambiguation)
Species of flowering plant in the nightshade family
(e.g., diphenidine, ephenidine, methoxphenidine) Morphinans (e.g., dextromethorphan (DXM), dextrorphan (DXO)) Inhalants (e.g., nitrous oxide (N2O), xenon
Datura_stramonium
Opioid analgesic
effects of the two isomers of racemethorphan are quite different, with dextromethorphan (DXM) being an antitussive at low doses and a disassociative at much
Levomethorphan
Topics referred to by the same term
Dexing may refer to: Recreational use of dextromethorphan Dexing, Tibet, village in the Tibet Autonomous Region of China Dexing, Jiangxi, city in Jiangxi
Dexing
Non-depolarizing neuromuscular blocker
Cyclopropane Dacuronium bromide Decamethonium Dehydronorketamine Desflurane Dextromethorphan Dextropropoxyphene Dextrorphan Diadonium DHβE Dihydrochandonium Dimethyltubocurarine
Rocuronium_bromide
Chemical compound
ketamine, methoxetamine, phencyclidine) Cyclobenzaprine Delucemine Dextromethorphan Dextrorphan Efavirenz Hypidone Medifoxamine Mesembrine Mifepristone
Org_6582
Topics referred to by the same term
Dexmedetomidine, a sedative medication frequently used in the ICU Dextromethorphan, an antitussive drug Dextrorotation, the property of clockwise-rotating
Dex
New Psychoactive Substance Dissociative Eticyclidine Derivative
(isopropylphenidine, isophenidine) Remacemide Morphinans Dextrallorphan (DXA) Dextromethorphan (DXM) Dextrorphan (DXO) Racemethorphan (methorphan) Racemorphan (morphanol)
3-Me-PCE
DEXTROMETHORPHAN
DEXTROMETHORPHAN
DEXTROMETHORPHAN
DEXTROMETHORPHAN
Boy/Male
Arabic
Leader
Boy/Male
Hindu
Worrier
Surname or Lastname
English (chiefly West Yorkshire)
English (chiefly West Yorkshire) : habitational name from any of several places named with Old English hēg ‘hay’ + lēah ‘wood’, ‘clearing’.
Girl/Female
Gujarati, Hindu, Indian, Kannada, Malayalam, Marathi, Mythological, Sanskrit, Tamil, Telugu
One with Loving Eyes; Goddess Parvati; Goddess Lakshmi
Male
Italian
Italian form of Latin Florentius, FIORENZO means "blossoming."
Girl/Female
Indian
The earth, Alive
Boy/Male
English
Form of Leander. Lionlike man.
Boy/Male
Hindu, Indian, Traditional
Sight
Boy/Male
Hindu, Indian, Punjabi, Sikh
Light of God
Female
Hawaiian
 Hawaiian form of Hebrew Sarah, KALA means "noble lady, princess." Compare with another form of Kala.
DEXTROMETHORPHAN
DEXTROMETHORPHAN
DEXTROMETHORPHAN
DEXTROMETHORPHAN
DEXTROMETHORPHAN