AI & ChatGPT searches , social queries for HUMAN INTERACTOME
Search references for HUMAN INTERACTOME. Phrases containing HUMAN INTERACTOME
See searches and references containing HUMAN INTERACTOME!
Search references for HUMAN INTERACTOME. Phrases containing HUMAN INTERACTOME
See searches and references containing HUMAN INTERACTOME!HUMAN INTERACTOME
Protein–protein interactions in human cells
The human interactome is the set of protein–protein interactions (the interactome) that occur in human cells. The sequencing of reference genomes, in particular
Human_interactome
Complete set of molecular interactions in a biological cell
In molecular biology, an interactome is the whole set of molecular interactions in a particular cell. The term specifically refers to physical interactions
Interactome
Type of stable macromolecular complex
transient interactions are very important for cell biology: the human interactome is enriched in such interactions, these interactions are the dominating
Protein_complex
Biological interrelationship
Virus-Host protein–protein interaction Networks knowledgebase PHI-base – Pathogen-Host Interaction Database Virus Human Interactome Network Map from Harvard
Host–pathogen_interaction
disease gene resides in can give better context for its action. Human proteome project Interactome Proteome anon. "BioPlex". harvard.edu. harvard.edu. Retrieved
BioPlex
Protein-coding gene in the species Homo sapiens
(July 2015). "The BioPlex Network: A Systematic Exploration of the Human Interactome". Cell. 162 (2): 425–440. doi:10.1016/j.cell.2015.06.043. PMC 4617211
C22orf31
Protein-coding gene in the species Homo sapiens
the Human Interactome". Cell. 162 (2): 425–440. doi:10.1016/j.cell.2015.06.043. PMC 4617211. PMID 26186194. "LGALS3 galectin 3 [ Homo sapiens (human) ]"
SLC46A3
Protein-coding gene in humans
Cannon JR, Ting L, Baltier K, et al. (May 2017). "Architecture of the human interactome defines protein communities and disease networks". Nature. 545 (7655):
CCDC60
Physical interactions and constructions between multiple proteins
discovering protein interactions on human interactome, specifically the interactome of Membrane proteins and the interactome of Schizophrenia-associated proteins
Protein–protein_interaction
Protein-coding gene in the species Homo sapiens
B. K., Obar, R. A., … Harper, J. W. (2017). Architecture of the human interactome defines protein communities and disease networks. Nature, 545(7655)
TMED5
(July 2015). "The BioPlex Network: A Systematic Exploration of the Human Interactome". Cell. 162 (2): 425–440. doi:10.1016/j.cell.2015.06.043. PMC 4617211
KICSTOR_subunit_2
Developmental protein
2022). "Distinctive Network Topology of Phase-Separated Proteins in Human Interactome". Journal of Molecular Biology. 434 (1) 167292. doi:10.1016/j.jmb
Dishevelled binding antagonist of beta catenin 1
Dishevelled_binding_antagonist_of_beta_catenin_1
NC, Poser I, Cox J, Nagaraj N, Toyoda Y, et al. (October 2015). "A human interactome in three quantitative dimensions organized by stoichiometries and
CCDC9B
Human protein
"Dual proteome-scale networks reveal cell-specific remodeling of the human interactome". Cell. 184 (11): 3022–3040.e28. doi:10.1016/j.cell.2021.04.011. PMC 8165030
C1orf52
Exploration of the Human Interactome". Cell. 162 (2): 425–40. doi:10.1016/j.cell.2015.06.043. PMC 4617211. PMID 26186194. The Human Protein Atlas entry
C8orf82
Series of chemical reactions resulting in a cell response
Information center for Protein Sequences, UNIHI – Unified Human Interactome, OPHID – Online Predicted Human Interaction Database, EcoCyc – Encyclopaedia of E
Biochemical_cascade
Protein and gene in humans
Q, Sahni N, et al. (November 2014). "A proteome-scale map of the human interactome network". Cell. 159 (5): 1212–1226. doi:10.1016/j.cell.2014.10.050
TMEM128
Technique in molecular biology
pivotal role in building large-scale synthetic human interactomes and in dissecting mechanisms in human disease. However, there are still some limitations
Reporter_gene
Protein-coding gene in the species Homo sapiens
Cannon JR, Ting L, Baltier K, et al. (May 2017). "Architecture of the human interactome defines protein communities and disease networks". Nature. 545 (7655):
SAAL1
Protein-coding gene in the species Homo sapiens
Q, Sahni N, et al. (November 2014). "A proteome-scale map of the human interactome network". Cell. 159 (5): 1212–1226. doi:10.1016/j.cell.2014.10.050
LCHN
Protein-coding gene in the species Homo sapiens
map of the human interactome network". Cell. 159 (5): 1212–1226. doi:10.1016/j.cell.2014.10.050. PMC 4266588. PMID 25416956. "NCBI Gene". Human C7orf31 genome
SPMIP4
Sequence in a genome
NC, Poser I, Cox J, Nagaraj N, Toyoda Y, et al. (October 2015). "A human interactome in three quantitative dimensions organized by stoichiometries and
Origin_of_replication
Human gene
"Dual proteome-scale networks reveal cell-specific remodeling of the human interactome". Cell. 184 (11): 3022–3040.e28. doi:10.1016/j.cell.2021.04.011. ISSN 0092-8674
CIMAP1C
R, An HJ, Lappe M, Wiuf C (May 2008). "Estimating the size of the human interactome". Proc. Natl. Acad. Sci. U.S.A. 105 (19): 6959–64. Bibcode:2008PNAS
Copurification
Protein-coding gene in the species Homo sapiens
Q, Sahni N, et al. (November 2014). "A proteome-scale map of the human interactome network". Cell. 159 (5): 1212–1226. doi:10.1016/j.cell.2014.10.050
C6orf201
Protein-coding gene in the species Homo sapiens
Q, Sahni N, et al. (November 2014). "A proteome-scale map of the human interactome network". Cell. 159 (5): 1212–26. doi:10.1016/j.cell.2014.10.050.
WBP11
Protein-coding gene in the species Homo sapiens
(July 2015). "The BioPlex Network: A Systematic Exploration of the Human Interactome". Cell. 162 (2): 425–440. doi:10.1016/j.cell.2015.06.043. PMC 4617211
RESF1
Branch of food chemistry
Visualisation of the human interactome network topology with the blue lines between proteins (represented as points) showing protein-protein interactions
Food_physical_chemistry
Protein-coding gene in the species Homo sapiens
Q, Sahni N, et al. (November 2014). "A proteome-scale map of the human interactome network". Cell. 159 (5): 1212–1226. doi:10.1016/j.cell.2014.10.050
DYNLL2
Protein-coding gene in humans
Q, Sahni N, et al. (November 2014). "A proteome-scale map of the human interactome network". Cell. 159 (5): 1212–1226. doi:10.1016/j.cell.2014.10.050
C12orf60
Protein-coding gene in humans
Q, Sahni N, et al. (November 2014). "A proteome-scale map of the human interactome network". Cell. 159 (5): 1212–1226. doi:10.1016/j.cell.2014.10.050
Carbonic_anhydrase_1
Protein-coding gene in the species Homo sapiens
Hao T, Roth FP, Vidal M (Nov 2014). "A proteome-scale map of the human interactome network". Cell. 159 (5): 1212–26. doi:10.1016/j.cell.2014.10.050.
TMCO6
Small protein domain found in some kinases and GTPases
domain-mediated protein-protein interaction networks, i.e., SH3 interactomes, revealed that worm SH3 interactome resembles the analogous yeast network because it is
SH3_domain
Protein
et al. (2015). "The BioPlex Network: A Systematic Exploration of the Human Interactome". Cell. 162 (2): 425–440. doi:10.1016/j.cell.2015.06.043. PMC 4617211
TMEM39B
Protein-coding gene in the species Homo sapiens
Additional TMEM239 protein interactions were identified through a human interactome mapping project. Synthenein-1 (SDCBP) is involved in the trafficking
TMEM239
Protein-coding gene in humans
Q, Sahni N, et al. (November 2014). "A proteome-scale map of the human interactome network". Cell. 159 (5): 1212–1226. doi:10.1016/j.cell.2014.10.050
REDIC1
Gene profile for C10orf88 (aka PAAT)
"Dual proteome-scale networks reveal cell-specific remodeling of the human interactome". Cell. 184 (11): 3022–40. doi:10.1016/j.cell.2021.04.011. PMC 8165030
PAAT_(protein)
Protein-coding gene in the species Homo sapiens
Weisswange I, Mansfeld J, Buchholz F, Hyman AA, Mann M (2017). "A human interactome in three quantitative dimensions organized by stoichiometries and
TPD52L2
Mammalian protein found in Homo sapiens
(2015-07-16). "The BioPlex Network: A Systematic Exploration of the Human Interactome". Cell. 162 (2): 425–440. doi:10.1016/j.cell.2015.06.043. ISSN 1097-4172
LENG9
Human gene
"Dual proteome-scale networks reveal cell-specific remodeling of the human interactome". Cell. 184 (11): 3022–3040.e28. doi:10.1016/j.cell.2021.04.011. PMC 8165030
UPF0602
Protein-coding gene in the species Homo sapiens
Charloteaux B, et al. (November 2014). "A proteome-scale map of the human interactome network". Cell. 159 (5): 1212–26. doi:10.1016/j.cell.2014.10.050.
TMUB2
Protein-coding gene in the species Homo sapiens
(July 2015). "The BioPlex Network: A Systematic Exploration of the Human Interactome". Cell. 162 (2): 425–40. doi:10.1016/j.cell.2015.06.043. PMC 4617211
TMTC4
"Consolidating the set of known human protein-protein interactions in preparation for large-scale mapping of the human interactome". Genome Biology. 6 (5): R40
Edward_Marcotte
On-line database of protein interactions
for any given organism, human interactome derived from structural complexes is available at ftp://ftp.ncbi.nih.gov/pub/mmdb/humanIntNw/. To focus on biologically
IBIS_(server)
data. The whole set of molecular interactions in the human cell, also known as the interactome, can be used for disease identification and prevention
Network_medicine
Human protein-coding gene
et al. (2015). "The BioPlex Network: A Systematic Exploration of the Human Interactome". Cell. 162 (2): 425–40. doi:10.1016/j.cell.2015.06.043. PMC 4617211
AKAP11
Hungarian-American physicist (born 1967)
disease module in the interactome explains disease heterogeneity, drug response and captures novel pathways and genes in asthma". Human Molecular Genetics
Albert-László_Barabási
Protein sequence motif
(July 2015). "The BioPlex Network: A Systematic Exploration of the Human Interactome". Cell. 162 (2): 425–440. doi:10.1016/j.cell.2015.06.043. PMC 4617211
FFAT_motif
Rod-shaped, gram-negative bacterium
on histidine and 501 phosphorylated threonines and 162 tyrosines. The interactome of E. coli has been studied by affinity purification and mass spectrometry
Escherichia_coli
Protein-coding gene in the species Homo sapiens
Q, Sahni N, et al. (November 2014). "A proteome-scale map of the human interactome network". Cell. 159 (5): 1212–1226. doi:10.1016/j.cell.2014.10.050
UBQLN1
Online database of proteins
PMID 14525934. Gandhi T.K.B.; et al. (March 2006). "Analysis of the human protein interactome and comparison with yeast, worm and fly interaction datasets"
Human Protein Reference Database
Human_Protein_Reference_Database
Protein found in most eukaryotes
"Dual proteome-scale networks reveal cell-specific remodeling of the human interactome". Cell. 184 (11): 3022–3040.e28. doi:10.1016/j.cell.2021.04.011. PMC 8165030
FAM86B1
Protein-coding gene in humans
Cannon JR, Ting L, Baltier K, et al. (May 2017). "Architecture of the human interactome defines protein communities and disease networks". Nature. 545 (7655):
WD repeat and coiled coil containing protein
WD_repeat_and_coiled_coil_containing_protein
F. (2006). "Global topological features of cancer proteins in the human interactome". Bioinformatics. 22 (18): 2291–2297. doi:10.1093/bioinformatics/btl390
Clique_percolation_method
Protein-coding gene in the species Homo sapiens
Exploration of the Human Interactome". Cell. 162 (2): 425–440. doi:10.1016/j.cell.2015.06.043. PMC 4617211. PMID 26186194. "ABHD8_HUMAN". UniProt. "METTL16
FAM149B1
Protein-coding gene in the species Homo sapiens
(Jul 2015). "The BioPlex Network: A Systematic Exploration of the Human Interactome". Cell. 162 (2): 425–40. doi:10.1016/j.cell.2015.06.043. PMC 4617211
L2HGDH
Mammalian gene
"Dual proteome-scale networks reveal cell-specific remodeling of the human interactome". Cell. 184 (11): 3022–3040.e28. doi:10.1016/j.cell.2021.04.011. PMC 8165030
MROH9
Human protein
(July 2015). "The BioPlex Network: A Systematic Exploration of the Human Interactome". Cell. 162 (2): 425–440. doi:10.1016/j.cell.2015.06.043. PMC 4617211
RTL6
Protein-coding gene in the species Homo sapiens
Cannon JR, Ting L, Baltier K, et al. (May 2017). "Architecture of the human interactome defines protein communities and disease networks". Nature. 545 (7655):
C5orf24
Biological term
interact with in three-dimensional space, thus discovering gene-set interactomes and pathways as new candidates for functional analysis and therapeutic
Epigenome
Measure of connection disorder in a network
applied to analyze the protein-protein interaction networks of virus-human interactomes, including the SARS-CoV-2, to unravel the systemic features of infection
Network_entropy
Human gene
(July 2015). "The BioPlex Network: A Systematic Exploration of the Human Interactome". Cell. 162 (2): 425–440. doi:10.1016/j.cell.2015.06.043. PMC 4617211
Transmembrane_protein_89
Any factor, whether abiotic or biotic, that influences living organisms in an ecosystem
influence on molecular pathologic processes including alterations in the interactome. This principle was first described in neoplastic diseases as "the unique
Environmental_factor
Oxygen-delivering blood cell and the most common type of blood cell
L, Kakhniashvili D, Daescu O (December 2007). "The human red blood cell proteome and interactome". Experimental Biology and Medicine. 232 (11): 1391–1408
Red_blood_cell
study of human phenotypes." PLoS Computational Biology 5.4 (2009): e1000353. Vidal, Marc, Michael E. Cusick, and Albert-Laszlo Barabasi. "Interactome networks
Human_disease_network
Protein family
Weisswange I, Mansfeld J, Buchholz F, Hyman AA, Mann M (October 2015). "A human interactome in three quantitative dimensions organized by stoichiometries and
Endoplasmic reticulum membrane protein complex
Endoplasmic_reticulum_membrane_protein_complex
Human C4orf19 gene
Cannon JR, Ting L, Baltier K, et al. (May 2017). "Architecture of the human interactome defines protein communities and disease networks". Nature. 545 (7655):
PGCKA1
Mammalian protein found in Homo sapiens
Q, Sahni N, et al. (November 2014). "A proteome-scale map of the human interactome network". Cell. 159 (5): 1212–1226. doi:10.1016/j.cell.2014.10.050
C19orf44
Novel human gene
Cannon JR, Ting L, Baltier K, et al. (May 2017). "Architecture of the human interactome defines protein communities and disease networks". Nature. 545 (7655):
ARMH1
Protein-coding gene in the species Homo sapiens
alongside other HSP70 proteins in a core sub-network of the wider chaperome interactome that functions as a proteostasis safeguard and that is repressed in aging
HSPA8
Mammalian protein found in Homo sapiens
"CCSB Interactome Database". interactome.dfci.harvard.edu. Retrieved 2020-05-03. "THAP1 - THAP domain-containing protein 1 - Homo sapiens (Human) - THAP1
Cholesin
Class of RNA molecules
Danckwardt S (June 2017). "sCLIP-an integrated platform to study RNA-protein interactomes in biomedical research: identification of CSTF2tau in alternative processing
Small_nuclear_RNA
Large-scale study of proteins
proteomics is to identify binary protein interactions, protein complexes, and interactomes. Several methods are available to probe protein–protein interactions
Proteomics
Technique in molecular biology
differentiation, proliferation, and development. By creating ChIA-PET interactome maps for DNA-binding regulatory proteins and promoter regions, we can
ChIA-PET
Totality of lipids in cells
characterised with an estimated 95% coverage; studies of the human lipidome are ongoing. For example, the human plasma lipidome consist of almost 600 distinct molecular
Lipidome
Multiprotein complex involved in transcription in eukaryotes
JT, Schlosser A (2017). "Proteomic Analysis of the Mediator Complex Interactome in Saccharomyces cerevisiae". Sci Rep. 7 43584. Bibcode:2017NatSR...743584U
Mediator_(coactivator)
Mammalian protein found in humans
PMID 12379659. Schulze WX, Deng L, Mann M (2005). "Phosphotyrosine interactome of the ErbB-receptor kinase family". Molecular Systems Biology. 1 2005
HER2
Comprehensive map of neural connections in the brain
connectome Human Connectome Project Interactome List of animals by number of neurons Neural coding Outline of brain mapping Outline of the human brain Lesion
Connectome
interactome networks by cross-species comparisons". BMC Systems Biology. 4: 36. doi:10.1186/1752-0509-4-36. PMC 2859380. PMID 20353594. Interactome.org
Interolog
Mammalian gene
1976. PMC 354828. PMID 59816. Schmidt MH, Dikic I (Dec 2005). "The Cbl interactome and its functions". Nature Reviews. Molecular Cell Biology. 6 (12): 907–918
CBL_(gene)
Transmembrane protein
PMID 18273061. Schulze WX, Deng L, Mann M (2005). "Phosphotyrosine interactome of the ErbB-receptor kinase family". Molecular Systems Biology. 1 (1)
Epidermal growth factor receptor
Epidermal_growth_factor_receptor
Protein-coding gene in the species Homo sapiens
AM, Kungl AJ (Nov 2005). "A proteomic snapshot of the human heat shock protein 90 interactome". FEBS Letters. 579 (28): 6350–4. Bibcode:2005FEBSL.579
Heat shock protein 90kDa alpha (cytosolic), member A1
Heat_shock_protein_90kDa_alpha_(cytosolic),_member_A1
Species of bacterium
Chowdhury S, Hepper S, Lodi MK, Saier MH, Uetz P (April 2021). "The Protein Interactome of Glycolysis in Escherichia coli". Proteomes. 9 (2): 16. doi:10.3390/proteomes9020016
Mycoplasma_pneumoniae
Protein-coding gene in the species Homo sapiens
(November 2011). "Proteomic dissection of the von Hippel-Lindau (VHL) interactome". Journal of Proteome Research. 10 (11): 5175–82. doi:10.1021/pr200642c
HNRNPLL
lacks the catalytic Asp residue in the HRD motif. The PSKH2 protein interactome is complex, and involves a number of membrane-associated proteins alongside
PSKH2
Protein-coding gene in the species Homo sapiens
Tu LC, Yan X, Hood L, Lin B (Apr 2007). "Proteomics analysis of the interactome of N-myc downstream regulated gene 1 and its interactions with the androgen
ACSL3
Protein found in humans
cellsig.2007.12.002. PMID 18234474. S2CID 28812149. "Results - mentha: the interactome browser". mentha.uniroma2.it. Retrieved 2017-05-04. Bass MD, Humphries
Syntenin-1
Protein-coding gene in the species Homo sapiens
Hermjakob H, Kerrien S, et al. (January 2007). "Disrupted in Schizophrenia 1 Interactome: evidence for the close connectivity of risk genes and a potential synaptic
IMMT
Biomolecule consisting of chains of amino acid residues
complement of biologically possible such interactions is known as the interactome. A systematic attempt to determine the structures of proteins representing
Protein
Protein
Costa VR, Sauer S, Meierhofer D, Ørom UA (2016-01-01). "Serial interactome capture of the human cell nucleus". Nature Communications. 7 11212. Bibcode:2016NatCo
Telomere-associated protein RIF1
Telomere-associated_protein_RIF1
Protein-coding gene in humans
Marra G, Schlapbach R, Jiricny J (2007). "Characterization of the interactome of the human MutL homologues MLH1, PMS1, and PMS2". J. Biol. Chem. 282 (5):
PMS1
Species of bacteria
SILAC. About 50% of the proteome has been quantified. Studies of the interactome have identified more than 3000 protein-protein interactions. This has
Helicobacter_pylori
Protein-coding gene in the species Homo sapiens
Protein - NCBI". www.ncbi.nlm.nih.gov. Retrieved 2016-04-30. "mentha: the interactome browser". mentha.uniroma2.it. Retrieved 2016-05-04. "GDS3834 / 12797
TMEM241
Protein-coding gene in the species Homo sapiens
Gandhi TK, Zhong J, Mathivanan S, et al. (2006). "Analysis of the human protein interactome and comparison with yeast, worm and fly interaction datasets"
Ubiquitin carboxyl-terminal hydrolase L5
Ubiquitin_carboxyl-terminal_hydrolase_L5
Protein-coding gene in the species Homo sapiens
Lucas DA, Chan KC, et al. (2004). "An investigation into the human serum "interactome"". Electrophoresis. 25 (9): 1289–98. doi:10.1002/elps.200405866
GDF10
Mental disorder with psychotic symptoms
"Neurodevelopmental disorders: mechanisms and boundary definitions from genomes, interactomes and proteomes". Translational Psychiatry. 3 (12): e329. doi:10.1038/tp
Schizophrenia
Gene thought to be critical for an organism's survival
(October 2008). "High-quality binary protein interaction map of the yeast interactome network". Science. 322 (5898): 104–10. Bibcode:2008Sci...322..104Y. doi:10
Essential_gene
Human protein
Ghavidel A, Cagney G, Emili A (September 2005). "A skeleton of the human protein interactome". Cell. 122 (6): 830–832. doi:10.1016/j.cell.2005.09.006. PMID 16179252
Cyclin-dependent_kinase_4
Protein-coding gene in the species Homo sapiens
Carbajo-Lozoya J, et al. (October 2011). "The SARS-coronavirus-host interactome: identification of cyclophilins as target for pan-coronavirus inhibitors"
Adipose-secreted signaling protein
Adipose-secreted_signaling_protein
Protein-coding gene in humans
Rosnoblet C, Vandamme J, Völkel P, Angrand PO (2011). "Analysis of the human HP1 interactome reveals novel binding partners". Biochemical and Biophysical Research
ADNP_(gene)
HUMAN INTERACTOME
HUMAN INTERACTOME
HUMAN INTERACTOME
HUMAN INTERACTOME
HUMAN INTERACTOME
HUMAN INTERACTOME
HUMAN INTERACTOME
HUMAN INTERACTOME
HUMAN INTERACTOME