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Comprehensive map of neural connections in the brain
A connectome (/kəˈnɛktoʊm/) is a comprehensive map of neural connections in the brain, and may be thought of as its "wiring diagram". These maps are available
Connectome
Research project
The Human Connectome Project (HCP) was a five-year project (later extended to 10 years) sponsored by sixteen components of the National Institutes of Health
Human_Connectome_Project
Study of mapping wiring diagrams
Connectomics is the production and study of connectomes, which are comprehensive maps of connections within an organism's nervous system. Study of neuronal
Connectomics
Connection graph of the brain of the fruit fly Drosophila melanogaster
A Drosophila connectome is a list of neurons in the Drosophila melanogaster (fruit fly) nervous system, and the chemical synapses between them. The fly's
Drosophila_connectome
American multi-disciplinary scientist
implications of the Human Connectome Project and what it would mean to map the connectome of a human brain. He has popularized the connectome theory through his
Sebastian_Seung
Structure of the invertebrate central nervous system
tracts called commissures. For the fruit fly Drosophila melanogaster, the connectome of the ventral nerve cord (and its connections to the brain) has been
Ventral_nerve_cord
2012 book by Sebastian Seung
Connectome: How the Brain's Wiring Makes Us Who We Are (2012) is a book by Sebastian Seung. It introduces basic concepts in neuroscience and then elaborates
Connectome_(book)
Processes which grow and shape an organism's nervous tissue over its lifetime(s)
interface of the Budapest Reference Connectome Server. The Budapest Reference Connectome Server (http://connectome.pitgroup.org) depicts the cerebral connections
Development of the nervous system
Development_of_the_nervous_system
Species of fruit fly
Center. Its complete genome was sequenced and first published in 2000. Its connectome, a list of the fly's neurons and their interconnections, is available
Drosophila_melanogaster
The Budapest Reference Connectome server computes the frequently appearing anatomical brain connections of 418 healthy subjects. It has been prepared from
Budapest_Reference_Connectome
2012 studio album by Muse
Human Connectome Project (24 October 2012). "Muse's latest album uses a Human Connectome Project rendering of white matter tracks". Human Connectome Project
The_2nd_Law
Free-living species of nematode
whole genome sequenced, and in 2019 it was the first organism to have its connectome (neuronal "wiring diagram") completed. As of 2024,[update] four Nobel
Caenorhabditis_elegans
2019 speculative fiction novel by Neal Stephenson
Sophia animates Dodge's connectome as an experiment on secure distributed computing, for her senior thesis at Princeton. The connectome remembers nearly nothing
Fall;_or,_Dodge_in_Hell
Organ central to the nervous system
Drosophila connectomes were achieved in the 2010s and 2020s; as fof 2026, there is one full female larval connectome, one full adult male CNS connectome, and
Brain
Term of art in cryonics
practical importance in contemporary medicine. Sebastian Seung (2012). Connectome: How the Brain's Wiring Makes Us Who We Are. Houghton Mifflin. p. 271
Information-theoretic_death
Simulation of a roundworm
called Sibernetic has been built for the project and models of the neural connectome and a muscle cell have been created in NeuroML format. A 3D model of the
OpenWorm
2020 American science documentary television series
of the most stirring stories in the history of science. 5 "The Cosmic Connectome" Ann Druyan Ann Druyan and Brannon Braga March 23, 2020 (2020-03-23) YNF205
Cosmos:_Possible_Worlds
in animals Brain size Brain–body mass ratio Encephalization quotient Connectome Connectomics Cranial capacity fr:Noogenèse Neuroscience and intelligence
List of animals by number of neurons
List_of_animals_by_number_of_neurons
American neuroscientist
flexible, efficient information processing. She will generate columnar connectomes for several brain areas to model a rule-based brain architecture. Using
Anna_Wang_Roe
organism), the proteome (the entire set of proteins expressed) and the connectome (the parts of the entire brain and their interconnections) the dysfunctome
Dysfunctome
Graphical representations of connectomics
connectogram here: Connectome – Comprehensive map of neural connections in the brain Connectomics – Study of mapping wiring diagrams Human Connectome Project –
Connectogram
Database of neural connections
subset of a connectome, since a connectome lists not only the connections between the structures, but also within them. Once a complete connectome of an organism
Projectome
Research project conducted by the US
Advanced Research Projects Activity (IARPA) with the goal of constructing a connectome of one cubic millimeter of a rodent's brain tissue—spanning many petabytes
MICrONS
American actor (born 1965 or 1966)
episodes 2020 Cosmos: A Spacetime Odyssey Mosso's Ghost Episode: "The Cosmic Connectome" 2022 NCIS: Los Angeles Martin Henderson Episode: "Live Free or Die Standing"
Rick_Pasqualone
American-British geneticist (born 1964)
theory to investigate the structure and function of simple neuronal connectomes, with the goal of understanding conserved computational principles in
William_Schafer
images to connectome reconstruction with WEBKNOSSOS". "NeuPRINT Connectome Explorer". "Codex - Connectome Data Explorer". "Synapse and Connectome Viewer"
History of microscale connectomics
History_of_microscale_connectomics
American psychologist
who is a professor at Harvard University. She is a member of the Human Connectome Project. Somerville was awarded the 2022 National Academy of Sciences
Leah_Somerville
cortex", the researchers reconstructed 9 connectomes across species: datasets of Mouse, Macaque and Human. Connectomes of higher organism's brains requires
Neural_circuit_reconstruction
development of FieldTrip is supported by funding from the BrainGain, Human Connectome and ChildBrain projects. The FieldTrip software is released as open source
FieldTrip
American neuroscientist
cortex in rodents. More recently, he has pioneered a new approach to connectome mapping using the methods of molecular biology, which may dramatically
Anthony_Zador
Neuroscience field
(2017). "Parameterizable consensus connectomes from the Human Connectome Project: the Budapest Reference Connectome Server v3.0". Cognitive Neurodynamics
Axon_guidance
Peer-to-peer file sharing protocol
can do so with little impact on the BOINC server. The developing Human Connectome Project uses BitTorrent to share their open dataset. Academic Torrents
BitTorrent
as well as databases such as OpenNeuro, SchizConnect, Developing Human Connectome Project, and FCP-INDI, and is seeing uptake in an increasing number of
Brain_Imaging_Data_Structure
Branch of neuroscience
been developed to aid research in that area. Nevertheless, complete connectomes of some model organisms have been obtained (see below). Is a field that
Neuroanatomy
Functional connectivity software is used to study functional properties of the connectome using functional Magnetic Resonance Imaging (fMRI) data in the resting
List of functional connectivity software
List_of_functional_connectivity_software
File-sharing website
computers around the world." The developing Human Connectome Project related to the Human Connectome Project uses the platform. "Researchers from three
Academic_Torrents
German physicist and neuroscientist
Virtual Brain" (TVB) is an open source software platform which turns brain connectomes derived from MRI into personalized whole-brain simulations, allowing
Viktor_K._Jirsa
Sex-specific adaptations
minimum vertex cover), the structural connectome of women are significantly "better" connected than the connectome of men. It was shown that the graph-theoretical
Sexual_dimorphism
Set of neuroscience techniques
strength of connection. At higher resolutions brain maps are called connectomes. These maps incorporate individual neural connections in the brain and
Brain_mapping
X-linked dominant genetic disorder
in impaired neuroplasticity, an integral part of memory and learning. Connectome changes have long been suspected to be involved in the sensory pathophysiology
Fragile_X_syndrome
Area of discrete mathematics
Shinohara, Russell T (2019-07-01). "Characterizing the role of the structural connectome in seizure dynamics". Brain. 142 (7): 1955–1972. doi:10.1093/brain/awz125
Graph_theory
Primary cell of the nervous system
Biological neuron model Cellular neuroscience Compartmental neuron models Connectome Dogiel cell Growth cone List of animals by number of neurons List of neuroscience
Neuron
Group of subcortical nuclei involved in the motor and reward systems
by diffusion spectrum imaging based on thirty subjects from the Human Connectome Project. Direct, indirect and hyperdirect pathways are visualized in different
Basal_ganglia
Type of artificial neural network
algorithms. A study published in Science in 2023 disclosed the complete connectome of an insect brain (specifically that of a fruit fly larva). This study
Residual_neural_network
Mental disorder
are just beginning to be mapped by modern neuroscience in the Human Connectome Project and CLARITY. Clinical psychiatry, furthermore, has begun to understand
Schizoaffective_disorder
Central organ of the human nervous system
research, and was followed in 2013 by the BRAIN Initiative. The Human Connectome Project was a five-year study launched in 2009 to analyse the anatomical
Human_brain
Neuroscientist
Cardona is a co-senior author of the first complete synaptic-resolution connectome of an insect brain, published in Science in 2023. This work mapped approximately
Albert_Cardona
Phylum of gelatinous marine animals
Niederhaus, Lara; Burkhardt, Pawel; Jékely, Gáspár (17 February 2026). "Neural connectome of the ctenophore statocyst". eLife. 14. doi:10.7554/eLife.108420. ISSN 2050-084X
Ctenophora
Neural pathway that executes voluntary movements
by diffusion spectrum imaging based on thirty subjects from the human connectome project (HCP MGH). Direct, indirect and hyperdirect pathways are visualized
Direct_pathway
Python module
Gerhard, Stephan, et al. "The connectome viewer toolkit: an open source framework to manage, analyze, and visualize connectomes." Frontiers in neuroinformatics
Graph-tool
Class of mollusks
Nyoman D.; Marshall, N. Justin (2020). "Toward an MRI-Based Mesoscale Connectome of the Squid Brain". iScience. 23 (1) 100816. Bibcode:2020iSci...23j0816C
Cephalopod
other sets of structural or functional units such as the proteasome and connectome. In analogy with the genome, where the genome is the total set of genes
Receptorome
Determination of neuron connections
electron microscopy). All three scales contribute to the generation of connectomes. When using light microscopy, the main distinction among neuronal tracing
Neuronal_tracing
Branch of psychology
societies with distinct ranks for individuals, despite having smaller connectomes relative to humans. Also, monkeys remain socially functioning after the
Evolutionary_psychology
of which reach over 3000 entries. Neuroinformatics Budapest Reference Connectome "Number of entries using search query 'database'". neuinfo.org. NIF. Retrieved
List of neuroscience databases
List_of_neuroscience_databases
Genus of comb jellies
cilia activities, feeding and different behaviors. The first neural connectome of a ctenophore was reconstructed from the aboral organ of M. leidyi cydippid
Mnemiopsis
Organisms used to study biology across species
was completely sequenced, and as of 2012, the only organism to have its connectome (neuronal "wiring diagram") completed. Arabidopsis thaliana is currently
Model_organism
Type of functional magnetic resonance imaging
utilizing a modified version of the Human Connectome Project (HCP) atlas, and found changes in the functional connectome of stroke patients during rehabilitative
Resting_state_fMRI
as the Human Connectome Project, the technique has been expanded to include large structural network atlases and multimodal-connectome datasets. Software
Lesion_network_mapping
Scientific research project
Brain/MINDS China Brain Project Decade of the Brain Decade of the Mind Human Connectome Project List of artificial intelligence projects SpiNNaker Brain atlas
Human_Brain_Project
Openly accessible data
definition. Open data may include non-textual material such as maps, genomes, connectomes, chemical compounds, mathematical and scientific formulae, medical data
Open_data
Large-scale brain network active when not focusing on an external task
Reisert, Marco; Blankenburg, Felix (2013). "The structural-functional connectome and the default mode network of the human brain". NeuroImage. 102: 142–151
Default_mode_network
American neurobiologist
software tools for brain visualization. David Van Essen also led the Human Connectome Project (HCP) as the Principal Investigator together with Co-Principal
David_Van_Essen
Neuroscientist
She made use of electron microscopy to map the entire larval Drosophila connectome, and studies the strengths of the connections between neurons that are
Marta_Zlatic
Creating a computer model of all or part of a brain
a map of the target organism neurons and their connections, called a connectome. Highly detailed simulations may precisely model the electrophysiology
Brain_simulation
extended by the group analysis module Lead Group, the connectome processing tools Lead Connectome and Lead Mapper, the intraoperative module Lead-OR, as
Lead-DBS
Swiss brain research initiative
biologically realistic model of neurons and an empirically reconstructed model connectome. There were a number of collaborations, including the Cajal Blue Brain
Blue_Brain_Project
Equation used in neuromorphic engineering
Kirchhoff's laws introduce a higher layer of complexity. A silver nanowire connectome can be described using graph theory, and have applications ranging from
Caravelli-Traversa-Di Ventra equation
Caravelli-Traversa-Di_Ventra_equation
Visual perception under low-light conditions
; Sigulinsky, C. L.; Lauritzen, J. S. (2014). "The AII amacrine cell connectome: A dense network hub". Frontiers in Neural Circuits. 8: 104. doi:10.3389/fncir
Scotopic_vision
American neuroscientist and psychologist
Access Series of Imaging Studies (OASIS) 1000 Functional Connectomes Project NIH Human Connectome Project (HCP) Brain Genomics Superstruct Project (GSP)
Randy_Buckner
American geneticist (born 1954)
neuroscience that proposes to map brain activity and establish a "functional connectome". Church is known for pioneering the specialized fields of personal genomics
George_Church_(geneticist)
Portuguese ballet dancer
Symphony in C Infra Concerto Medusa Flight Pattern Ceremony of Innocence Connectome Untouchable Woolf Works Corybantic Games The Instrument in The Cellist
Marcelino_Sambé
Part of an animal that coordinates actions and senses
nematode Caenorhabditis elegans, has been completely mapped out in a connectome including its synapses. Every neuron and its cellular lineage has been
Nervous_system
International scientific research project (1990–2003)
name standards Human Brain Project – Scientific research project Human Connectome Project – Research project Human Epigenome Project Human Microbiome Project –
Human_Genome_Project
Neuroimaging software
is no longer under active development and has been superseded by the Connectome Workbench software. Analysis of group anatomical differences using sulcal
Caret_(software)
Human-based computation game
Eyewire players. Flywire would go on to complete and publish the first connectome of an adult fruit fly, a structure with about 140,000 neurons. A sequel
Eyewire
Structure at the rear of the vertebrate brain, beneath the cerebrum
S2CID 53272245. Boonstra, Jackson Tyler (2025-01-28). "The Cerebellar Connectome". Behav Brain Res. 482 115457. doi:10.1016/j.bbr.2025.115457. PMID 39884319
Cerebellum
American biomedical engineer (born 1980)
Some of his notable work in this area includes the analysis of the first connectome of an insect brain (that of a Drosophila larva) and his use of machine
Joshua_Vogelstein
Peptides released by neurons as intercellular messengers
Isabel; Vértes, Petra E.; Schafer, William R. (2023). "The neuropeptidergic connectome of C. elegans". Neuron. 111 (22). Elsevier: 3570–3589. doi:10.1016/j.neuron
Neuropeptide
American psychologist and neuroscientist
biological data on himself for an extended period of time. Called the MyConnectome Project, this study lasted 18 months, during which Poldrack was scanned
Russell_Poldrack
British ballet dancer (born 1993)
Belleroche in Strapless Dr. John Brown in Like Water for Chocolate The Cellist Connectome Corybantic Games The Illustrated 'Farewell' Medusa Multiverse Obsidian
Matthew_Ball_(dancer)
Network with non-trivial topological features
Introduction to Network Neuroscience: How to build, model, and analyse connectomes - 0800-10:00 | OHBM". pathlms.com. Retrieved 2020-03-11. T. Wilhelm,
Complex_network
Danish neuroscientist (born 1970)
one of the cardinal symptoms, namely anhedonia, the lack of pleasure. Connectome Happiness Resting state fMRI Motivation Pleasure Reward system Biologically
Morten_Kringelbach
State of tiredness, exhaustion or loss of energy
"Neural Mechanisms of Mental Fatigue Revisited: New Insights from the Brain Connectome". Engineering. 5 (2): 276–286. Bibcode:2019Engin...5..276Q. doi:10.1016/j
Fatigue
Brain imaging centre in Cardiff, Wales
stimulation (EBS) laboratories 10 cognitive method laboratories the first connectome scanner outside the United States, a Siemens 3-tesla Connectom system
CUBRIC
Biological causes of variation in human personality
of paranoia. The use of functional connectomes to predict individual differences is known as "functional connectome fingerprinting" and allows researcher
Biological basis of personality
Biological_basis_of_personality
American neuroscientist
collaboration with Sebastian Seung and Winfried Denk, to construct a full connectome of the mouse retina. The lab is also interested in inhibitory interneurons
Jeff_W._Lichtman
Swiss neuroscientist, Professor of Psychiatry at Harvard Medical School
"Reward-Related Neural Circuitry in Depressed and Anxious Adolescents: A Human Connectome Project". Journal of the American Academy of Child and Adolescent Psychiatry
Diego_A._Pizzagalli
Russian ballerina (born 1986)
Part 3 Soloist Class Concert Remansos Cinque In the Upper Room: Soloist Connectome Tetractys - The Art of the Fugue The Wind: Dancer Solo for Two Passacaille
Natalia_Osipova
South Korean entertainer (born 1987)
dancer DJ MC actor model Instrument Vocals Years active 2005–present Label Connectome Entertainment Member of SS501 Five O One Website http://www.kyu-jong.com/
Kim_Kyu-jong
German neuroscientist & researcher
brain networks, particularly the structural architecture of the cerebral connectome. Much of his research has examined the anatomical wiring of the primate
Claus_C._Hilgetag
Simplified conventional pictorial representation of an electrical circuit
as fire alarm or closed-circuit television or other special services. Connectome Electrical drawing Electrical wiring Circuit diagram Schematic "Electrical
Wiring_diagram
Alexander S.; et al. (October 2024). "Whole-brain annotation and multi-connectome cell typing of Drosophila". Nature. 634 (8032): 139–152. doi:10.1038/s41586-024-07686-5
2024_in_science
Bonilha pioneered work on diffusion MRI, diffusion tractography, and connectome lesion-symptom mapping, demonstrating that residual structural connectivity
Leonardo_Bonilha
Balancing organ in certain aquatic invertebrate animals
Niederhaus, Lara; Burkhardt, Pawel; Jékely, Gáspár (2026-02-17). "Neural connectome of the ctenophore statocyst". eLife. 14. doi:10.7554/eLife.108420. ISSN 2050-084X
Statocyst
Hospital in MA , United States
used primarily for research, including the high-gradient field Human Connectome Project scanner, a 7 tesla magnet for human radiography, and a combined
Athinoula A. Martinos Center for Biomedical Imaging
Athinoula_A._Martinos_Center_for_Biomedical_Imaging
Hungarian-American physicist (born 1967)
the functions of individual neurons within the Caenorhabditis elegans connectome. This application provided direct experimental confirmation of network
Albert-László_Barabási
Impairment in the clarity of consciousness
February 2021. Kucyi, Aaron; Davis, Karen D. (2015). "The dynamic pain connectome". Trends in Neurosciences. 38 (2): 86–95. doi:10.1016/j.tins.2014.11.006
Clouding_of_consciousness
Brain imaging software package
April 2022 and it is a core tool in the processing pipelines of the Human Connectome Project, the UK Biobank, the Adolescent Brain Cognitive Development Study
FreeSurfer
Neurological assessment tool
and cost. The NIH Toolbox battery of measures will be used by The Human Connectome Project (HCP) to understand the relationship between brain connectivity
NIH_Toolbox
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