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Class of enzymes which split esters into an acid and alcohol via hydrolysis
In biochemistry, an esterase is a class of enzyme that splits esters into an acid and an alcohol in a chemical reaction with water called hydrolysis (and
Esterase
Test for white blood cells in urine
Leukocyte esterase is a type of esterase enzyme released by white blood cells (leukocytes), particularly neutrophils, when they are activated or recruited
Leukocyte_esterase
Histological staining compound
α-Naphthyl butyrate esterase, also referred to as naphthyl butyrate esterase or butyrate esterase, is a histological stain specific for white blood cells
Butyrate_esterase
Topics referred to by the same term
A-esterase may refer to one of two enzymes: Arylesterase Aryldialkylphosphatase This disambiguation page lists articles associated with the title A-esterase
A-esterase
Index of enzymes associated with the same name
Esterase D may refer to: Methylumbelliferyl-acetate deacetylase, an enzyme Carboxylesterase, an enzyme This set index page lists enzyme articles associated
Esterase_D
Esterase that lyses choline-based esters
The enzyme cholinesterase (EC 3.1.1.8, choline esterase; systematic name acylcholine acylhydrolase) catalyses the hydrolysis of choline-based esters, several
Cholinesterase
The enzyme sinapine esterase (EC 3.1.1.49) catalyzes the hydrolysis reaction: sinapine H2O sinapinic acid + choline Sinapine and sinapinic
Sinapine_esterase
The enzyme feruloyl esterase (EC 3.1.1.73) catalyzes the reaction feruloyl-polysaccharide + H2O ⇌ {\displaystyle \rightleftharpoons } ferulate + polysaccharide
Feruloyl_esterase
Protein-coding gene in the species Homo sapiens
Neuropathy target esterase, also known as patatin-like phospholipase domain-containing protein 6 (PNPLA6), is an esterase enzyme that in humans is encoded
Neuropathy_target_esterase
Drugs that inhibit acetylcholinesterase
contamination with the organophosphate. It is believed that the neuropathy target esterase (NTE) is affected by the organophosphate which induces the disease. However
Acetylcholinesterase inhibitor
Acetylcholinesterase_inhibitor
Glycoprotein present in some enveloped viruses
Hemagglutinin esterase (HEs) is a glycoprotein that certain enveloped viruses possess and use as an invading mechanism. HEs helps in the attachment and
Hemagglutinin_esterase
The enzyme sterol esterase (EC 3.1.1.13) catalyzes the reaction a sterol ester + H2O ⇌ {\displaystyle \rightleftharpoons } a sterol + a fatty acid This
Sterol_esterase
Class of enzymes
The enzyme acetylxylan esterase (EC 3.1.1.72) catalyzes the deacetylation of xylans and xylo-oligosaccharides. This enzyme belongs to the family of hydrolases
Acetylxylan_esterase
Class of enzymes which use water to break a chemical bond
of hydrolase enzymes are esterases including lipases, phosphatases, glycosidases, peptidases, and nucleosidases. Esterases cleave ester bonds in lipids
Hydrolase
Class of enzymes
The enzyme acetylajmaline esterase (EC 3.1.1.80, AAE, 2β(R)-17-O-acetylajmalan:acetylesterase, acetylajmalan esterase; systematic name 17-O-acetylajmaline
Acetylajmaline_esterase
Disorder resulting in severe swelling
in hereditary angioneurotic edema: Absence of serum inhibitor of C' 1-esterase". Am. J. Med. 35 (1). The American Journal of Medicine: 37–44. doi:10
Hereditary_angioedema
Class of enzymes
hormone esterase (EC 3.1.1.59, systematic name methyl-(2E,6E,10R)-10,11-epoxy-3,7,11-trimethyltrideca-2,6-dienoate acylhydrolase, JH esterase) catalyzes
Juvenile-hormone_esterase
Disease characterized by rapid swelling
related to bradykinin may occur due to an inherited problem known as C1 esterase inhibitor deficiency, medications known as angiotensin-converting enzyme
Angioedema
Primary cholinesterase in the body
discussed at Cholinesterase § Types and nomenclature. For acetylcholine esterase (AChE), reversible inhibitors are those that do not irreversibly bond to
Acetylcholinesterase
Medical condition
Acquired C1 esterase inhibitor deficiency, also referred to as acquired angioedema (AAE), is a rare medical condition that presents as body swelling that
Acquired C1 esterase inhibitor deficiency
Acquired_C1_esterase_inhibitor_deficiency
Class of enzymes
The enzyme cocaine esterase (EC 3.1.1.84, CocE, hCE2, hCE-2, human carboxylesterase 2; systematic name cocaine benzoylhydrolase) catalyses the reaction
Cocaine_esterase
Mammalian protein found in humans
C1-inhibitor (C1-inh, C1 esterase inhibitor) is a protease inhibitor belonging to the serpin superfamily. Its main function is the inhibition of the complement
C1-inhibitor
Class of enzymes which cleave fats via hydrolysis
these are usually treated separately from "conventional" lipases. Unlike esterases, which function in water, lipases "are activated only when adsorbed to
Lipase
Protein-coding gene in the species Homo sapiens
Neurexophilin and PC-esterase domain family member 2 is a protein that in humans is encoded by the NXPE2 gene. GRCh38: Ensembl release 89: ENSG00000204361
Neurexophilin and PC-esterase domain family member 2
Neurexophilin_and_PC-esterase_domain_family_member_2
Chemical reaction
pig liver esterase is the enantioselective conversion of an ester to a carboxylic acid through the action of the enzyme pig liver esterase (EC 3.1.1.1)
Asymmetric ester hydrolysis with pig-liver esterase
Asymmetric_ester_hydrolysis_with_pig-liver_esterase
Enzyme
The enzyme fumonisin B1 esterase (EC 3.1.1.87, fumD (gene); systematic name fumonisin B1 acylhydrolase) catalyses the reaction fumonisin B1 2 H2O
Fumonisin_B1_esterase
Class of enzymes
carboxylesterase, pyrethroid-hydrolysing esterase, pyrethroid-hydrolyzing esterase, pyrethroid-selective esterase, pyrethroid-cleaving enzyme, permethrinase
Pyrethroid_hydrolase
Chemical agents that inhibit Cholinesterase
Cholinesterase inhibitors (ChEIs), also known as anti-cholinesterase, are chemicals that prevent the breakdown of the neurotransmitter acetylcholine or
Cholinesterase_inhibitor
Class of enzymes
The enzyme 4-methyloxaloacetate esterase (EC 3.1.1.44) catalyzes the reaction oxaloacetate 4-methyl ester + H2O ⇌ {\displaystyle \rightleftharpoons } oxaloacetate
4-methyloxaloacetate_esterase
Protein-coding gene in humans
C1r subcomponent (EC 3.4.21.41, activated complement C1r, C overbar 1r esterase, C1r) is a protein involved in the complement system of the innate immune
Complement_component_1r
The enzyme polyneuridine-aldehyde esterase (EC 3.1.1.78) catalyzes the following reaction: polyneuridine aldehyde + H2O ⇌ {\displaystyle \rightleftharpoons
Polyneuridine-aldehyde esterase
Polyneuridine-aldehyde_esterase
Birth defect in which the intestine lacks certain nerves
Histopathology of Hirschsprung disease showing abnormal acetylcholine esterase (AchE)-positive nerve fibers (brown) in the mucosa Specialty Medical genetics
Hirschsprung's_disease
Chemical compound
prokinetic benzamide derivative. These drugs inhibit dopamine and acetylcholine esterase enzyme and have a gastrokinetic effect. Itopride is indicated for the treatment
Itopride
Diagnostic tool used in urinalysis
contain esterases. Neutrophil granulocytes are the leukocytes most commonly associated with urinary infections. A positive test for leukocyte esterase normally
Urine_test_strip
Potentially fatal complication of pregnancy
activate complement. Additionally, another study showed activity levels of C1 esterase inhibitor, a key regulator of the complement system, are significantly
Amniotic_fluid_embolism
Protein-coding gene in the species Homo sapiens
Paraoxonase 1 (PON1) also known as Serum paraoxonase and arylesterase 1, A esterase, homocysteine thiolactonase or serum aryldialkylphosphatase 1, is an enzyme
PON1
Class of enzymes
include diacetoxybutynylbithiophene acetate esterase, and 3,4-diacetoxybutinylbithiophene:4-acetate esterase. Pensl R, Suetfeld R (1985). "Occurrence of
5-(3,4-diacetoxybut-1-ynyl)-2,2'-bithiophene deacetylase
5-(3,4-diacetoxybut-1-ynyl)-2,2'-bithiophene_deacetylase
Species of virus
N-acetyl-9-O-acetylneuraminic acid receptor. It has the hemagglutinin esterase (HE) gene, which distinguishes it as a member of the genus Betacoronavirus
Human_coronavirus_HKU1
Protein-coding gene in the species Homo sapiens
CES1 gene. The protein is also historically known as serine esterase 1 (SES1), monocyte esterase and cholesterol ester hydrolase (CEH). Three transcript variants
Carboxylesterase_1
Class of enzymes
Factor D (EC 3.4.21.46, C3 proactivator convertase, properdin factor D esterase, factor D (complement), complement factor D, CFD, adipsin) is a protein
Factor_D
Chemical compound
producing masculinization and suitable for androgen replacement therapy. Esterase enzymes break the ester bond in testosterone enanthate, releasing free
Testosterone_enanthate
common use include ornithine esterase, and 5-N 5-L-ornithine-ester hydrolase. Emery T (June 1976). "Fungal ornithine esterases: relationship to iron transport"
Fusarinine-C_ornithinesterase
Form of L-carnitine
dietary supplement. Acetylcarnitine is broken down in the blood by plasma esterases to carnitine which is used by the body to transport fatty acids into the
Acetylcarnitine
The enzyme bis(2-ethylhexyl)phthalate esterase (EC 3.1.1.60) catalyzes the reaction bis(2-ethylhexyl)phthalate + H2O ⇌ {\displaystyle \rightleftharpoons
Bis(2-ethylhexyl)phthalate esterase
Bis(2-ethylhexyl)phthalate_esterase
Class of enzymes
ali-esterase, B-esterase, butyrate esterase, butyryl esterase, carboxylesterase 1 carboxylesterase 2 carboxylesterase 3 esterase A, esterase B, esterase D
Carboxylesterase
The enzyme α-amino-acid esterase (EC 3.1.1.43) catalyzes the reaction an α-amino acid ester + H2O ⇌ {\displaystyle \rightleftharpoons } an α-amino acid
Alpha-amino-acid_esterase
Class of enzymes
acylhydrolase. Other names in common use include tropine esterase, atropinase, and atropine esterase. Plasma atropinesterase exhibits high enantiospecific
Tropinesterase
Topics referred to by the same term
commonly used in microbiology to identify certain organisms Hemagglutinin esterase, a viral protein Hematoxylin and eosin stain, a popular staining method
He
Species of scorpion
that C. vittatus venom contains the enzymes alkaline phosphatase, esterase, esterase lipase, acid phosphatase, and phospholipase A. While a C. vittatus
Striped_bark_scorpion
Chemical compound
ester of benzylpenicillin, is a prodrug processed to benzylpenicillin by esterases. It has no detectable teratogenic risk to the fetus. Agersborg HP, Batchelor
Penamecillin
Species of virus
an additional shorter spike-like surface protein called hemagglutinin esterase (HE) as well as the larger coronavirus spike protein. de Groot, R.J; et al
Betacoronavirus_1
Class of enzymes
Hydroxynitrile lyases of the α/β hydrolase fold are closely related to esterases. All members of the α/β hydrolase fold contain a conserved catalytic triad
(S)-hydroxynitrile_lyase
Protein found in humans
Complement component 1s (EC 3.4.21.42, C1 esterase, activated complement C1s, complement C overbar 1r, C1s) is a protein involved in the complement system
Complement_component_1s
Anatomic structure in pit vipers
adenosine triphosphate, monoamine oxidase, generalized esterases, and acetylcholine esterase have also been found in it. When prey comes into range,
Loreal_pit
Chemical compound (nerve agent)
inhibits AChE, but it is also a substrate for other esterases. Reaction of soman with these esterases allows for the detoxication of the compound. No metabolic
Soman
Chemical compound
complex + HF The median lethal dose between 150–215 mg/kg (acetylcholine esterase inactivator). PMSF should be handled only inside a fume hood and while
PMSF
In enzymology, a retinyl-palmitate esterase (EC 3.1.1.21) is an enzyme that catalyzes the chemical reaction. retinyl palmitate + H2O ⇌ {\displaystyle \rightleftharpoons
Retinyl-palmitate_esterase
Chemical compound
ripening of fruit. In over-ripe fruits, due to the presence of pectic methyl esterase enzyme, the pectin gets largely converted to pectic acid which is water-insoluble
Pectic_acid
Chemical compound
carnitine that includes an additional glycine component. Due to tissues esterases enzymes, GPLC should act as a prodrug and lead to glycine, carnitine and
Glycine_propionyl-L-carnitine
Class of enzymes
Methylumbelliferyl-acetate deacetylase (EC 3.1.1.56, esterase D) is an enzyme that catalyzes the reaction 4-methylumbelliferyl acetate H2O H2O
Methylumbelliferyl-acetate deacetylase
Methylumbelliferyl-acetate_deacetylase
Pharmaceutical drug
treatment of acute attacks of hereditary angioedema (HAE) in adults with C1-esterase-inhibitor deficiency. It is not effective in angioedema caused by medication
Icatibant
Class of enzymes
organophosphate hydrolase, parathion hydrolase, paraoxonase, and parathion aryl esterase; systematic name aryltriphosphate dialkylphosphohydrolase) is a metalloenzyme
Aryldialkylphosphatase
Pharmaceutical compound
psilocybin (4-PO-DMT). The drug is cleaved into psilocin by non-specific esterases. O-Glutarylpsilocin was first described in the scientific literature in
RE-109
Psychedelic drug
psilocybin. Psilocin ester prodrugs like 4-AcO-DMT are cleaved into psilocin by esterase enzymes. A 2025 in-vitro study examined the stability and metabolism of
4-AcO-DMT
Chemical compound found in some species of mushrooms
stomach or the actions of alkaline phosphatase (ALP) and non-specific esterases in tissues and fluids. Psilocin is demethylated and oxidatively deaminated
Psilocybin
Flavorant food additive
enzymes such as proteases (not including the usual rennet), lipases and esterases. An incubation period under controlled conditions is required for proper
Enzyme-modified_cheese
Development of hives after contact with water
Cholinergic urticaria Aquagenic urticaria Other urticaria Acquired C1 esterase inhibitor deficiency Adrenergic urticaria Autoimmune urticaria Exercise
Aquagenic_urticaria
wax-ester acylhydrolase. Other names in common use include jojoba wax esterase, and WEH. Huang AH, Moreau RA, Liu KD (1978). "Development and properties
Wax-ester_hydrolase
Pharmaceutical fungicide or fungistatic used to treat and prevent mycosis
terbinafine)[medical citation needed] Triacetin – hydrolysed to acetic acid by fungal esterases Undecylenic acid – an unsaturated fatty acid derived from natural castor
Antifungal
Family of evolutionarily related proteins
eukaryotes have many distinct esterases. The different types include those that act on carboxylic esters (EC 3.1.1). Carboxyl-esterases have been classified into
Carboxylesterase_type_B
Protein family
methyl-accepting chemotaxis protein methyl-esterase, CheB methylesterase, methylesterase CheB, protein methyl-esterase, protein carboxyl methylesterase, PME
Protein-glutamate methylesterase
Protein-glutamate_methylesterase
Chemical compound
is enzymatically hydrolyzed to its monoesters by pancreatic cholesterol esterase (CEase) in pigs and cows. These mammalian pancreatic CEases have been found
Diethyl_phthalate
Painful or uncomfortable urination
the predictive value goes even higher. If the patient only has leukocyte esterase or bacteria in the urine, then dysuria may suggest that the patient probably
Dysuria
Class of enzymes
The enzyme mycophenolic acid acyl-glucuronide esterase (EC 3.1.1.93, mycophenolic acid acyl-glucuronide deglucuronidase; AcMPAG deglucuronidase; systematic
Mycophenolic acid acyl-glucuronide esterase
Mycophenolic_acid_acyl-glucuronide_esterase
The enzyme Pimelyl-[acyl-carrier protein] methyl ester esterase (EC 3.1.1.85, BioH; systematic name pimelyl-[acyl-carrier protein] methyl ester hydrolase
Pimelyl-(acyl-carrier protein) methyl ester esterase
Pimelyl-(acyl-carrier_protein)_methyl_ester_esterase
Compound that is metabolized into a pharmacologically active drug
aglycone. For example, salicin is a β-D-glucopyranoside that is cleaved by esterases to release salicylic acid. Aspirin (acetylsalicylic acid), first made
Prodrug
Class of enzymes
PETases are an esterase class of enzymes that catalyze the breakdown (via hydrolysis) of polyethylene terephthalate (PET) plastic to monomeric mono-2-hydroxyethyl
PETase
Chemical compound
breakdown process of modafinil, modafinil is primarily hydrolyzed by an esterase or amidase enzyme into modafinil acid. The apparent clearance of modafinil
Modafinil_acid
Chemical compound
is broken down into its active metabolite, desfesoterodine, by plasma esterases. Fesoterodine has the advantage of allowing more flexible dosage than
Fesoterodine
Class of enzymes
acylhydrolase. Other names in common use include 11-cis-retinol palmitate esterase, and RPH. This enzyme participates in retinol metabolism. This enzyme has
11-cis-retinyl-palmitate hydrolase
11-cis-retinyl-palmitate_hydrolase
Opioid analgesic drug
controlled-substances laws. Diacetyldihydromorphine is quickly metabolized by plasma esterase enzymes into dihydromorphine, in the same way that diamorphine is metabolized
Diacetyldihydromorphine
Tropane alkaloid and stimulant drug
elimination half-life of 0.7–1.5 hours and is extensively metabolized by plasma esterases and also by liver cholinesterases, with only about 1% excreted unchanged
Cocaine
Antihypertensive drug of the calcium channel blocker class
a half-life of approximately one minute. It is rapidly inactivated by esterases. It was approved by the United States Food and Drug Administration on
Clevidipine
Protein-coding gene in the species Homo sapiens
Gene ontology Molecular function 1-alkyl-2-acetylglycerophosphocholine esterase activity platelet-activating factor acetyltransferase activity protein
PAFAH1B3
Species of virus
Embecovirus, an additional shorter spike protein called hemagglutinin-esterase (HE). Genetic and antigenic analyses reveal significant similarities between
Human_coronavirus_OC43
Enzyme hydrolysing long-chain fatty esters
"Catalog of 680 variations among eight cytochrome p450 ( CYP) genes, nine esterase genes, and two other genes in the Japanese population". Journal of Human
Carboxylesterase_2
Region of the human brain
cord via reticulospinal tract.[citation needed] Physostigmine, a choline-esterase inhibitor, elevates endogenous levels of acetylcholine and causes a rise
Rostral_ventrolateral_medulla
Cancer of the myeloid line of blood cells
combination of a myeloperoxidase or Sudan black stain and a nonspecific esterase stain will provide the desired information in most cases. The myeloperoxidase
Acute_myeloid_leukemia
Topics referred to by the same term
PLE may refer to: Photoluminescence excitation Pig-liver esterase Pittsburgh and Lake Erie Railroad, P&LE Polymorphous light eruption, a skin condition
PLE
Species of archaeon
Saccharolobus solfataricus is a species of thermophilic archaeon. It was transferred from the genus Sulfolobus to the new genus Saccharolobus with the
Sulfolobus_solfataricus
Class of enzymes
The enzyme 1-alkyl-2-acetylglycerophosphocholine esterase (EC 3.1.1.47) catalyzes the reaction 1-alkyl-2-acetyl-sn-glycero-3-phosphocholine + H2O ⇌ {\displaystyle
1-alkyl-2-acetylglycerophosphocholine esterase
1-alkyl-2-acetylglycerophosphocholine_esterase
Class of enzymes which split thiol esters into an acid and alcohol
which belong to the esterase family. Esterases, in turn, are one type of the several hydrolases known. Thioesterases exhibit esterase activity (splitting
Thioesterase
Chemical compound
this purpose, an acetomethoxyester group is added to SNARF-1. Cellular esterases cleave off SNARF-1, and its transport out of the cells can be measured
Seminaphtharhodafluor
Vitamin A chemical compound
Adel; Lichtin, J. Leon; Bronaugh, Robert L. (1994). "Characterization of Esterase and Alcohol Dehydrogenase Activity in Skin. Metabolism of Retinyl Palmitate
Retinyl_palmitate
Organ of the digestive system and endocrine system of vertebrates
fats include lipase, phospholipase A2, lysophospholipase, and cholesterol esterase. Enzymes that break down starch and other carbohydrates include amylase
Pancreas
Combination drug
N-acetylcysteine (NAC), which is a mucus-thinning drug. Upon contact with tissue esterases, TGA releases both TAFGE and NAC. As a standalone medication, NAC is widely
Thiamphenicol glycinate acetylcysteine
Thiamphenicol_glycinate_acetylcysteine
Protein-coding gene in the species Homo sapiens
carboxylic ester hydrolase activity sterol esterase activity triglyceride lipase activity methyl indole-3-acetate esterase activity Cellular component endoplasmic
Carboxylesterase_3
Class of enzymes
chlorogenase, and chlorogenic acid esterase. Schobel B, Pollmann W (1980). "Isolation and characterization of a chlorogenic acid esterase from Aspergillus niger"
Chlorogenate_hydrolase
Species of virus
Betacoronavirus, subgenus Embecovirus, it has a surface protein called hemagglutinin esterase (HE) in addition to the four structural proteins shared by all coronaviruses
Bovine_coronavirus
Chemical compound
After entering cells by diffusion, CFDA-SE is cleaved by intracellular esterase enzymes to form CFSE. As its reactive succinimidyl ester group is unmodified
Carboxyfluorescein diacetate succinimidyl ester
Carboxyfluorescein_diacetate_succinimidyl_ester
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