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Psychoactive drug, often called ecstasy
(MDMA), commonly known as ecstasy in tablet form, and molly in crystal form, is an entactogen with stimulant and minor psychedelic properties. MDMA was
MDMA
Class of psychoactive drugs that produce empathic experiences
openness—that is, empathy—as particularly observed and reported for experiences with MDMA (ecstasy). This class of drug is distinguished from the classes of hallucinogens
Entactogen
Entactogen drug
related to 3,4-methylenedioxymethamphetamine (MDMA; "ecstasy"). It is the β-keto or cathinone analogue of MDMA. The drug is usually taken orally, but can
Methylone
Psychoactive drug taken by mouth
(MDMA; midomafetamine; "ecstasy"), a racemic mixture of (R)-MDMA and (S)-MDMA. Like MDMA, (R)-MDMA is an entactogen or empathogen. It is taken by mouth. The
(R)-MDMA
Topics referred to by the same term
MDMA in Wiktionary, the free dictionary. MDMA is a psychoactive drug, commonly known as the recreational drug Ecstasy. MDMA may also refer to: MDMA (film)
MDMA_(disambiguation)
Controlled administration of psychoactive drug MDMA to facilitate psychotherapy efficacy
MDMA-assisted psychotherapy (MDMA-AT), also known as entactogen-assisted psychotherapy, is the use of prescribed doses of MDMA or sometimes other entactogens
MDMA-assisted_psychotherapy
Pharmaceutical compound
MDMA/citalopram is a combination of the entactogen and monoamine releasing agent 3,4-methylenedioxymethamphetamine (MDMA; also known as midomafetamine
MDMA/citalopram
Entactogen, stimulant, and psychedelic drug of the amphetamine family
history of psychotherapeutic and recreational use that predates that of MDMA, dating back to at least the mid-1960s. It has been described as the first
3,4-Methylenedioxyamphetamine
Pharmaceutical compound
d2-MDMA, also known as d2-3,4-methylenedioxymethamphetamine or as deuterated-MDMA (D-MDMA), is an entactogen and stimulant of the phenethylamine, amphetamine
D2-MDMA
MDMA prodrug
Lys-MDMA, or lysine-MDMA, also known as N-(L-lysinamidyl)-MDMA, is an intended prodrug of MDMA which was being investigated for possible use as a pharmaceutical
Lys-MDMA
Psychedelic drug
in 1975. The drug also emerged as a novel recreational designer drug and MDMA (ecstasy) substitute in the mid-1980s. Subsequently, it became a controlled
2C-B
Pharmaceutical compound
(3T-MDMA) or as MY100, is a putative entactogen of the phenethylamine and amphetamine families related to 3,4-methylenedioxy-N-methylamphetamine (MDMA).
SDMA_(drug)
Chemical compound
the MDMA analogue so far known that has the closest effects and so-called "magic" to MDMA itself. Other analogues that lack the full quality of MDMA include
5-MAPB
Pharmaceutical compound
Non-racemic MDMA, also known by the developmental code names ALA-002 and AM-1002, are non-racemic mixtures of the MDMA (midomafetamine; "ecstasy") enantiomers
Non-racemic_MDMA
Pharmaceutical compound
6-Bromo-MDMA, also known as 6-bromo-3,4-methylenedioxy-N-methylamphetamine or as 2-bromo-4,5-methylenedioxymethamphetamine (2-Br-4,5-MDMA), is a psychoactive
6-Bromo-MDMA
American pharmaceutical company
California that is developing novel MDMA-like entactogens and psychedelics as medicines. Its stated goal is to develop new MDMA-like drugs with improved effectiveness
Tactogen
Chemical compound
UWA-001 (also known as α-phenyl-MDMA and methylenedioxymephenidine) is a phenethylamine derivative invented at the University of Western Australia as non-toxic
UWA-001
Pharmaceutical compound
Homo-MDMA (HMDMA), also known as α,N-dimethyl-3-(3,4-methylenedioxyphenyl)propylamine, is an entactogen-like drug of the phenylpropylamine group related
Homo-MDMA
Class of compounds based upon the amphetamine structure
methoxyphenamine, selegiline, amfepramone (diethylpropion), pyrovalerone, MDMA (ecstasy), and DOM (STP). Some of amphetamine's substituted derivatives occur
Substituted_amphetamine
Chemical compound
3-Methylenedioxymethamphetamine, also known as 2,3-MDMA or ORTHO-MDMA, is a positional isomer of the recreational drug 3,4-MDMA (commonly known as Ecstasy or Molly)
2,3-Methylenedioxymethamphetamine
2,3-Methylenedioxymethamphetamine
2017 American crime drama film
MDMA (also known as Cardinal X or Angie X) is a 2017 American crime drama film written and directed by Angie Wang, and produced by Wang and Fire Horse
MDMA_(film)
MDMA metabolite
(MDMA). It is formed from MDMA by O-demethylation via cytochrome P450 enzymes including CYP2D6 as well as CYP1A2 and CYP3A4. Like MDMA, HHMA is
3,4-Dihydroxymethamphetamine
Designer drug combination mimicking MDMA
is a combination recreational and designer drug which is described as an MDMA-like entactogen. It is a mixture of the entactogen 5-MAPB or MDAI, the stimulant
Borax_combo
American public benefit corporation
Corporation (MAPS PBC), is a public benefit corporation (PBC) developing MDMA ("ecstasy") for potential medicinal use. It was founded and is part-owned
Resilient_Pharmaceuticals
American drug activist
research MDMA and other psychedelics through legal clinical trials. MAPS pursued a lengthy FDA approval process, hoping mainstream acceptance of MDMA therapy
Rick_Doblin
Pharmaceutical compound
DFMDMA, also known as F2-MDMA or as 3,4-(difluoromethylenedioxy)methamphetamine, is a chemical compound of the phenethylamine, amphetamine, and MDxx families
DFMDMA
American neuroscientist
hallucinogens, and other psychoactive drugs. He is considered to be an expert on MDMA and other entactogens and is an influential figure in the psychedelic medicine
Matthew_J._Baggott
Chemical compound
disorder. New MDMA prodrugs are in the development phase at MiHKAL GmbH in Switzerland. A phase 1 clinical trial comparing MDMA, MDA, Lys-MDMA, and Lys-MDA
Lys-MDA
Chemical compound
is an entactogen of the 2-aminoindane family which is related to MDMA and produces similar subjective effects. It acts as a selective serotonin
MDAI
Retracted article published in Science
dopaminergic neurotoxicity in primates after a common recreational dose regimen of MDMA ("ecstasy")", is an article by George A. Ricaurte that was published in September
Retracted article on dopaminergic neurotoxicity of MDMA
Retracted_article_on_dopaminergic_neurotoxicity_of_MDMA
Pharmaceutical compound
N-dimethyl analogue of MDA and the N-methyl derivative of MDMA. The drug is a known synthetic impurity of MDMA and has also been described as a possible novel designer
MDDMA
Drug that blocks hallucinogen effects
the subjective effects of MDMA, consistent with the proposed involvement of carriermediated 5-HT release in the effects of MDMA (Farre et al., 2007; Liechti
Trip_killer
K L M N O P Q R S T U V W X Y Z 1. Mai – Helden bei der Arbeit (2008) – MDMA 10 to Midnight (1983) – cannabis 21 Grams (2003) – cocaine 21 Jump Street
List_of_drug_films
MDMA derivative drug
6-Chloro-MDMA, also known as 6-chloro-3,4-methylenedioxy-N-methylamphetamine or as 2-chloro-4,5-methylenedioxy-N-methylamphetamine (2-Cl-4,5-MDMA), is a
6-Chloro-MDMA
2025 child homicide in California, US
for benzodiazepines and methamphetamine/MDMA, though additional testing returned no confirmed presence of MDMA or methamphetamine, and none of these substances
Killing of Celeste Rivas Hernandez
Killing_of_Celeste_Rivas_Hernandez
MDMA analogue
(MDMA) which was developed in an attempt to create an improved MDMA alternative for potential clinical use. It is the analogue of MDMA in which
SeDMA
Chemical compound
amphetamine families. It is a monoamine releasing agent and a metabolite of MDMA and MDA. The bis-glutathionyl metabolite of α-methyldopamine is slightly
Α-Methyldopamine
Pharmaceutical compound
entactogen-like drug of the benzylamine family related to MDMA. It is the analogue of MDMA in which the side chain has been shortened by one carbon atom
MDM1EA
Chemical compound
phenethylamine, amphetamine, and phenylisobutylamine families related to MDMA. It is known by the nicknames "Eden" and "Methyl-J". MBDB was first synthesized
MBDB
Medical condition
tests in research settings, for instance with the oxytocin-elevating drug MDMA. Efforts are underway towards developing diagnostic tests for oxytocin deficiency
Oxytocin_deficiency
orientation, researchers have utilised MDMA, or as it is commonly referred to, Ecstasy (3,4-methylenedioxymethamphetamine). MDMA is known to affect serotonin neurons
Role of serotonin in visual orientation processing
Role_of_serotonin_in_visual_orientation_processing
not been disclosed, Mydecine has patented 5-BZT-MDMA (MY100) and 6-BZT-MDMA (MY101) as short-acting MDMA analogues. List of psychedelic pharmaceutical companies
Mydecine
Pharmaceutical compound
N-desmethyl analogue of 3,4-methylenethiooxy-N-methylamphetamine (SDMA; 3T-MDMA). Similarly to MDA, SDA is a serotonin–norepinephrine–dopamine releasing
SDA_(drug)
Non-profit media organization and self described watchdog Journalism
aggressive tactics, and politically motivated campaigning against approval of MDMA-assisted psychotherapy. These claims have also been denied and disputed by
Psymposia
researched are MDMA, psilocybin, ketamine. Each substance has different rationales for treatment and various treatment methods. MDMA was first synthesized
Psychedelic treatments for trauma-related disorders
Psychedelic_treatments_for_trauma-related_disorders
2023 book by Rachel Nuwer
Love: MDMA and the Quest for Connection in a Fractured World is a 2023 nonfiction book by American author Rachel Nuwer about the entactogen drug MDMA ("ecstasy")
I_Feel_Love_(book)
health charity. In 2013, Gabor Maté referred Buisson for a clinical trial of MDMA-assisted psychotherapy for management of treatment-resistant post-traumatic
Meaghan_Buisson
Category of recreational drugs
adolescents and young adults. Club drugs range from entactogens such as MDMA ("ecstasy"), 2C-B ("nexus") and inhalants (e.g., nitrous oxide and poppers)
Club_drug
MDMA analogue
(MDMA) which was developed in an attempt to create an improved MDMA alternative for potential clinical use. It is the analogue of MDMA in which
TDMA_(drug)
Chemical compound
known as 2-methoxy-4,5-methylenedioxy-N-methylamphetamine or as 6-methoxy-MDMA, is a psychoactive drug of the phenethylamine, amphetamine, and MDxx families
Methyl-MMDA-2
Chemical compound
deficiency, MDMA fails to elevate oxytocin levels and shows greatly blunted entactogenic effects. Accordingly, carbetocin partially substitutes for MDMA in drug
Oxytocin_receptor_agonist
Class of psychoactive drugs
prototypical agent of this class is 3,4-methylenedioxy-N-methylamphetamine (MDMA; "ecstasy"). Other notable MDxx class substances include 3,4-methylenedioxyamphetamine
Substituted methylenedioxyphenethylamine
Substituted_methylenedioxyphenethylamine
Pharmaceutical compound
considerably less potent than MDA as an MRA in vitro. IDA fully substituted for MDMA and LSD in animal drug discrimination tests, albeit with 5- to 7-fold lower
3,4-Isopropylidenedioxyamphetamine
3,4-Isopropylidenedioxyamphetamine
Recreational drug
users may swallow, snort, or inject it. Its effects are similar to those of MDMA, amphetamines, and cocaine, producing euphoria and increased sociability
Mephedrone
Chemical compound
DFMDA was active at the serotonin transporter (SERT) similarly to MDA and MDMA and with intermediate affinity between the two. It was developed with the
DFMDA
Compounds that damage or destroy monoaminergic neurons
neurotoxins para-chloroamphetamine (PCA), methylenedioxymethamphetamine (MDMA), and 5,7-dihydroxytryptamine (5,7-DHT); the dopaminergic neurotoxins oxidopamine
Monoamine_neurotoxin
MDMA analogue
(MDMA) which was developed in an attempt to create an improved MDMA alternative for potential clinical use. It is the analogue of MDMA in which
ODMA_(drug)
October 2024. It is likely to become outdated with time. Midomafetamine (MDMA; "ecstasy") – serotonin, norepinephrine, and dopamine releasing agent, weak
List of investigational hallucinogens and entactogens
List_of_investigational_hallucinogens_and_entactogens
Use of psychedelic drugs as treatment
psilocybin and psilocin (mushrooms), ayahuasca, DMT, 5-MeO-DMT, ibogaine and MDMA. As of 2021, psychedelic drugs are controlled substances in most countries
Psychedelic_therapy
Entactogen
phenethylamine, amphetamine, and MDxx families. It is the N-hydroxy homologue of MDMA ("Ecstasy"), and the N-methyl homologue of MDOH. In his book PiHKAL (Phenethylamines
3,4-Methylenedioxy-N-hydroxy-N-methylamphetamine
3,4-Methylenedioxy-N-hydroxy-N-methylamphetamine
German chemist
pharmaceutical giant Merck, first described the synthesis of the chemical MDMA. In 1911, Köllisch published his doctoral dissertation on the topic of indole
Anton_Köllisch
Pharmaceutical compound
MYCO-007 is an MDMA-like entactogen that is under development for the treatment of psychiatric disorders. It is a short-acting MDMA analogue. MYCO-007
MYCO-007
American politician (born 1963)
Breakthrough Therapies Act to allow Schedule I drugs such as psilocybin and MDMA to be rescheduled when they are designated as breakthrough therapies by the
Rand_Paul
Mixture of different psychoactive drugs
originated in Latin America, specifically Colombia around 2018. Ketamine and MDMA are the most common ingredients, although cocaine, methamphetamine, oxycodone
Tusi_(drug)
Chemical compound
4-methylenedioxymethamphetamine (MDMA). It is a slightly more potent stimulant than MDMA in rodents. The drug is substantially less potent than MDMA as a monoamine releasing
4-Hydroxy-3-methoxymethamphetamine
4-Hydroxy-3-methoxymethamphetamine
Pharmaceutical compound
6-MBPB partially substituted for MDMA in animal drug discrimination tests at lower doses and fully substituted for MDMA at the highest dose, suggesting
6-MBPB
2011 Trae the Truth single
Lupe Fiasco, Big Boi, & Wale and American singer Poo Bear, also known as MDMA. The song was released as a digital download on December 6, 2011. "I'm On"
I'm_On
Turkish-American neuroscientist
anti-social, became more social after exposure to the psychoactive drug MDMA, which acts on a serotonin pathway The research suggests that there is a
Gül_Dölen
Events regarding psychedelic drugs
ayahuasca, peyote, and Sonoran Desert toad venom. This timeline also includes MDMA, which is closely related to psychedelics, but not other types of hallucinogens
Timeline of psychedelic legalization and decriminalization
Timeline_of_psychedelic_legalization_and_decriminalization
Chemical compound
has been identified as a synthetic impurity formed in certain routes of MDMA manufacture. Substituted methylenedioxyphenethylamine 3-Chlorophenmetrazine
Methylenedioxyphenmetrazine
MDMA metabolite
active metabolite of 3,4-methylenedioxymethamphetamine (MDMA). It is substantially less potent than MDMA or 3,4-methylenedioxyamphetamine (MDA) as a monoamine
4-Hydroxy-3-methoxyamphetamine
4-Hydroxy-3-methoxyamphetamine
Pharmaceutical compound
families related to MDMA which is under development for potential medical use. It is a cyclized phenethylamine and is a derivative of MDMA in which the α position
APA-01
Chemical compound
in black market tablets sold as MDMA (ecstasy) although its effects are markedly different compared to those of MDMA. The consequences of such deception
Para-Methoxyamphetamine
Hallucinogenic class of psychoactive drug
as those which are atypical or adjacent to psychedelia like ketamine and MDMA, respectively. Classic psychedelics generally cause specific psychological
Psychedelic_drug
arrested by Jackson and Lucy, is made to admit she is a drug mule carrying MDMA in her stomach and is offered a deal. When a condom bursts, she is taken
List_of_The_Rookie_episodes
Pharmaceutical compound
MYCO-006 is an MDMA-like entactogen that is under development for the treatment of psychiatric disorders. It is a short-acting and fast-onset MDMA analogue
MYCO-006
Chemical compound
that of the illegal drug MDMA, the only difference being the replacement of the α-methyl group with an α-cyclopropyl group. MDMA has been found in animal
UWA-101
Behavioral measure in animals
(SRIs) (which block MDMA-induced SERT-mediated serotonin release), or serotonin 5-HT2B receptor knockout (which likewise blocks MDMA-induced serotonin release)
Locomotor_activity
American nonprofit organization
guidelines for clinical drug research. Included in MAPS' research efforts are MDMA (methylenedioxymethamphetamine) for the treatment of posttraumatic stress
Multidisciplinary Association for Psychedelic Studies
Multidisciplinary_Association_for_Psychedelic_Studies
American medical television drama series
confess before she leaves. Santos and Mohan treat a patient seizing from an MDMA overdose without a superior's approval, enraging Langdon and causing him
The_Pitt
American psychological thriller television miniseries
video goes public and finds solace in Amber, a young woman who offers her MDMA, with Amber asking Natalie to "roll with me." Unbeknownst to Natalie, "Amber"
Cape_Fear_(TV_series)
Medicine – non-racemic MDMA (AM-1002), AM-1004, AM-1006 Atai Life Sciences (merged with Beckley Psytech) – DMT (VLS-01), (R)-MDMA (EMP-01), ibogaine (IBX-210
List of psychedelic pharmaceutical companies
List_of_psychedelic_pharmaceutical_companies
Chemical compound
the phenethylamine, amphetamine, and EDxx families. It is an analogue of MDMA where the methylenedioxy ring has been replaced by an ethylenedioxy ring
EDMA
Chemical compound
N-t-BOC-MDMA, also known as N-tert-butoxycarbonyl-MDMA, is a chemical compound which can be both a synthetic precursor to, or a prodrug of the entactogenic
N-t-BOC-MDMA
1995 death of an English woman
1995, during her birthday celebration at home, Betts consumed an ecstasy (MDMA) tablet and subsequently drank approximately 7 litres (1.8 US gal) of water
Death_of_Leah_Betts
Entactogen drug
is the N-methylated derivative of MDAT, similarly to the relationship of MDMA to MDA. It has been theorized to have less long-term neurotoxicity and less
MDMAT
Australian schoolgirl (1980–1995)
encephalopathy, following acute water intoxication secondary to ingestion of MDMA. Wood's death was covered widely in the news media, produced debate on drug
Anna_Wood_(born_1980)
Excess deposition of extracellular matrix in the cardiac muscle
users of MDMA ("ecstasy") found that they did have heart valve changes suggestive of early cardiac fibrosis, which were not present in non-MDMA using controls
Cardiac_fibrosis
American billionaire investor
developing MDMA-assisted psychotherapy treatments. The acquisition followed the Food and Drug Administration's rejection of Lykos's application for MDMA therapy
Antonio_Gracias
Anti-narcotics initiative in Kerala, India
dismantling trafficking networks, curbing the spread of synthetic drugs such as MDMA, and reducing the supply of narcotics around schools and colleges. "Toofan"
Operation_Toofan
Chemical compound
unintentional sideproduct during the synthesis of MDMA using PMK glycidate as a precursor. It was identified in MDMA pills. The biological properties of this molecule
M-α-HMCA
American actor (born 1963)
misused alcohol. He also admitted to using other substances such as marijuana, MDMA and cocaine but denied ever having been addicted to any of them. In November
Johnny_Depp
(MDEA) Methylenedioxymethamphetamine (MDMA) (S)-MDMA and (R)-MDMA (EMP-01, DT402/MM402) Non-racemic MDMA (ALA-002; AM-1002) Methylenedioxyhydroxyamphetamine
List_of_entactogens
Spanish pharmacologist expert in psychedelics
pharmacology known for his work on psychedelic therapy, particularly ayahuasca, MDMA, iboga, as well as cannabis. Born in Madrid, Spain, José Carlos Bouso graduated
José_Carlos_Bouso
Chemical compound
5-Methoxy-3,4-methylenedioxymethamphetamine (MMDMA; 5-MeO-MDMA) is a designer drug of the substituted methylenedioxyphenethylamine (MDxx) class. Little
MMDMA
Class of compounds
serotonin 5-HT2B receptor antagonism with RS-127445 has been found to abolish MDMA-induced serotonin release and locomotor hyperactivity. As with reported findings
Serotonin_releasing_agent
Subsequently, the Yensens worked in the Canadian phase 2 clinical trials of MDMA-assisted psychotherapy for post-traumatic stress disorder (PTSD) conducted
Richard_Yensen
drug raids in Mumbai and Bengaluru relating to an alleged international MDMA (ecstasy) drugs racket. Based on evidence collected during the raids, the
2020_Bengaluru_drug_raids
American crime comedy-drama TV series
with Cricket and nearly sleeps with Sam after Ashe drugs the guests with MDMA. Elsewhere, Tori is arrested for drunk driving, while Mel is also arrested
Your Friends & Neighbors (TV series)
Your_Friends_&_Neighbors_(TV_series)
Use of drugs with the primary intention to alter the state of consciousness
cannabis (though some areas have legalised cannabis use), cocaine, opioids, MDMA, amphetamine, methamphetamine, psychedelics, benzodiazepines, and barbiturates
Recreational_drug_use
MDMA
MDMA
MDMA
MDMA
Boy/Male
Hindu
Girl/Female
Tamil
Humid
Surname or Lastname
English
English : habitational name from a place called Heblethwaite in Cumbria, named with Old English hēope ‘rosehip’ or hēopa ‘bramble’ + Old Norse þveit ‘clearing’.
Boy/Male
Hindu
Son of ky, Home sweet home
Girl/Female
Australian, Chinese
Wonderful; Excellent; Clever; Subtle
Girl/Female
Arabic, Muslim
Name of a Sahabiyyah RA
Girl/Female
Muslim
Wise, Sensible, Intelligent woman
Girl/Female
Arabic, British, English
Innocent
Boy/Male
Hindu, Indian
Another Name for Sage Visvamitra
Boy/Male
Muslim
The Biblical Noah is the English language equivalent.
MDMA
MDMA
MDMA
MDMA
MDMA