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COPANLISIB

  • Copanlisib

    • Chemical compound

    copanlisib from the US market. Data for safety and efficacy of copanlisib are described in the consumer-targeted FDA Drug Trial Snapshot. Copanlisib can

    Copanlisib

    Copanlisib

    Copanlisib

  • Phosphoinositide 3-kinase inhibitor

    • Medical drug glass

    survival under copanlisib treatment, but also considerably more severe and serious side effects. The phase III trial CHRONOS-4 compares copanlisib + immunochemotherapy

    Phosphoinositide 3-kinase inhibitor

    Phosphoinositide 3-kinase inhibitor

    Phosphoinositide_3-kinase_inhibitor

  • ATC code L01

    • Pharmaceutical drug classification

    L01EL05 Pirtobrutinib L01EL06 Tirabrutinib L01EM01 Idelalisib L01EM02 Copanlisib L01EM03 Alpelisib L01EM04 Duvelisib L01EM05 Parsaclisib L01EM06 Inavolisib

    ATC code L01

    ATC_code_L01

  • Nirogacestat

    • Chemical compound

    Entinostat Panobinostat Romidepsin Vorinostat) PIKI (Pi3K) (Alpelisib Copanlisib‡ Duvelisib Idelalisib Inavolisib Umbralisib‡) IDH (Enasidenib Ivosidenib

    Nirogacestat

    Nirogacestat

    Nirogacestat

  • Bleomycin

    • Glycopeptide antibiotic used to treat various cancers

    Entinostat Panobinostat Romidepsin Vorinostat) PIKI (Pi3K) (Alpelisib Copanlisib‡ Duvelisib Idelalisib Inavolisib Umbralisib‡) IDH (Enasidenib Ivosidenib

    Bleomycin

    Bleomycin

    Bleomycin

  • Carfilzomib

    • Chemical compound

    Entinostat Panobinostat Romidepsin Vorinostat) PIKI (Pi3K) (Alpelisib Copanlisib‡ Duvelisib Idelalisib Inavolisib Umbralisib‡) IDH (Enasidenib Ivosidenib

    Carfilzomib

    Carfilzomib

    Carfilzomib

  • Indolocarbazole

    • Class of chemical compounds

    Entinostat Panobinostat Romidepsin Vorinostat) PIKI (Pi3K) (Alpelisib Copanlisib‡ Duvelisib Idelalisib Inavolisib Umbralisib‡) IDH (Enasidenib Ivosidenib

    Indolocarbazole

    Indolocarbazole

    Indolocarbazole

  • Lomustine

    • Chemical compound

    Entinostat Panobinostat Romidepsin Vorinostat) PIKI (Pi3K) (Alpelisib Copanlisib‡ Duvelisib Idelalisib Inavolisib Umbralisib‡) IDH (Enasidenib Ivosidenib

    Lomustine

    Lomustine

    Lomustine

  • Cladribine

    • Pharmaceutical drug

    Entinostat Panobinostat Romidepsin Vorinostat) PIKI (Pi3K) (Alpelisib Copanlisib‡ Duvelisib Idelalisib Inavolisib Umbralisib‡) IDH (Enasidenib Ivosidenib

    Cladribine

    Cladribine

    Cladribine

  • Pentostatin

    • Chemical compound

    Entinostat Panobinostat Romidepsin Vorinostat) PIKI (Pi3K) (Alpelisib Copanlisib‡ Duvelisib Idelalisib Inavolisib Umbralisib‡) IDH (Enasidenib Ivosidenib

    Pentostatin

    Pentostatin

    Pentostatin

  • Celecoxib

    • Nonsteroidal anti-inflammatory medication

    Entinostat Panobinostat Romidepsin Vorinostat) PIKI (Pi3K) (Alpelisib Copanlisib‡ Duvelisib Idelalisib Inavolisib Umbralisib‡) IDH (Enasidenib Ivosidenib

    Celecoxib

    Celecoxib

    Celecoxib

  • Cisplatin

    • Chemical compound and pharmaceutical drug

    Entinostat Panobinostat Romidepsin Vorinostat) PIKI (Pi3K) (Alpelisib Copanlisib‡ Duvelisib Idelalisib Inavolisib Umbralisib‡) IDH (Enasidenib Ivosidenib

    Cisplatin

    Cisplatin

    Cisplatin

  • Cyclophosphamide

    • Medication used as chemotherapy and to suppress the immune system

    Entinostat Panobinostat Romidepsin Vorinostat) PIKI (Pi3K) (Alpelisib Copanlisib‡ Duvelisib Idelalisib Inavolisib Umbralisib‡) IDH (Enasidenib Ivosidenib

    Cyclophosphamide

    Cyclophosphamide

    Cyclophosphamide

  • Indolent lymphoma

    • Medical condition

    antibody therapy. Phosphatidylinositol 3-kinase (PI3K) inhibitors such as copanlisib, idelalisib, or duvelisib may be used to treat relapsed indolent lymphoma

    Indolent lymphoma

    Indolent lymphoma

    Indolent_lymphoma

  • Rucaparib

    • Chemical compound

    Entinostat Panobinostat Romidepsin Vorinostat) PIKI (Pi3K) (Alpelisib Copanlisib‡ Duvelisib Idelalisib Inavolisib Umbralisib‡) IDH (Enasidenib Ivosidenib

    Rucaparib

    Rucaparib

    Rucaparib

  • Tretinoin

    • Medication

    Entinostat Panobinostat Romidepsin Vorinostat) PIKI (Pi3K) (Alpelisib Copanlisib‡ Duvelisib Idelalisib Inavolisib Umbralisib‡) IDH (Enasidenib Ivosidenib

    Tretinoin

    Tretinoin

    Tretinoin

  • Melphalan flufenamide

    • Alkylating type cancer drug

    Entinostat Panobinostat Romidepsin Vorinostat) PIKI (Pi3K) (Alpelisib Copanlisib‡ Duvelisib Idelalisib Inavolisib Umbralisib‡) IDH (Enasidenib Ivosidenib

    Melphalan flufenamide

    Melphalan flufenamide

    Melphalan_flufenamide

  • Arsenic trioxide

    • Industrial chemical and medication

    Entinostat Panobinostat Romidepsin Vorinostat) PIKI (Pi3K) (Alpelisib Copanlisib‡ Duvelisib Idelalisib Inavolisib Umbralisib‡) IDH (Enasidenib Ivosidenib

    Arsenic trioxide

    Arsenic trioxide

    Arsenic_trioxide

  • Doxorubicin

    • Chemotherapy medication

    Entinostat Panobinostat Romidepsin Vorinostat) PIKI (Pi3K) (Alpelisib Copanlisib‡ Duvelisib Idelalisib Inavolisib Umbralisib‡) IDH (Enasidenib Ivosidenib

    Doxorubicin

    Doxorubicin

    Doxorubicin

  • Fluorouracil

    • Chemotherapy medication

    Entinostat Panobinostat Romidepsin Vorinostat) PIKI (Pi3K) (Alpelisib Copanlisib‡ Duvelisib Idelalisib Inavolisib Umbralisib‡) IDH (Enasidenib Ivosidenib

    Fluorouracil

    Fluorouracil

  • Methotrexate

    • Chemotherapy and immunosuppressant medication

    Entinostat Panobinostat Romidepsin Vorinostat) PIKI (Pi3K) (Alpelisib Copanlisib‡ Duvelisib Idelalisib Inavolisib Umbralisib‡) IDH (Enasidenib Ivosidenib

    Methotrexate

    Methotrexate

    Methotrexate

  • Vorasidenib

    • Anti-cancer medication

    Entinostat Panobinostat Romidepsin Vorinostat) PIKI (Pi3K) (Alpelisib Copanlisib‡ Duvelisib Idelalisib Inavolisib Umbralisib‡) IDH (Enasidenib Ivosidenib

    Vorasidenib

    Vorasidenib

    Vorasidenib

  • Bisantrene

    • Chemical compound

    Entinostat Panobinostat Romidepsin Vorinostat) PIKI (Pi3K) (Alpelisib Copanlisib‡ Duvelisib Idelalisib Inavolisib Umbralisib‡) IDH (Enasidenib Ivosidenib

    Bisantrene

    Bisantrene

    Bisantrene

  • P110α

    • Human protein-coding gene

    currently under going clinical trials for solid tumors. In September 2017 Copanlisib, inhibiting predominantly p110α and p110δ, got FDA approval for the treatment

    P110α

    P110α

    P110α

  • Vepdegestrant

    • Chemical compound

    Entinostat Panobinostat Romidepsin Vorinostat) PIKI (Pi3K) (Alpelisib Copanlisib‡ Duvelisib Idelalisib Inavolisib Umbralisib‡) IDH (Enasidenib Ivosidenib

    Vepdegestrant

    Vepdegestrant

    Vepdegestrant

  • PI3K/AKT/mTOR pathway

    • Cell cycle regulation pathway

    lymphocytic leukemia/small lymphocytic lymphoma and follicular lymphoma. Copanlisib is approved for relapsed follicular lymphoma in patients who have received

    PI3K/AKT/mTOR pathway

    PI3K/AKT/mTOR pathway

    PI3K/AKT/mTOR_pathway

  • Alkylating antineoplastic agent

    • Pharmaceutical drugs

    Entinostat Panobinostat Romidepsin Vorinostat) PIKI (Pi3K) (Alpelisib Copanlisib‡ Duvelisib Idelalisib Inavolisib Umbralisib‡) IDH (Enasidenib Ivosidenib

    Alkylating antineoplastic agent

    Alkylating antineoplastic agent

    Alkylating_antineoplastic_agent

  • Temozolomide

    • Cancer medication

    Entinostat Panobinostat Romidepsin Vorinostat) PIKI (Pi3K) (Alpelisib Copanlisib‡ Duvelisib Idelalisib Inavolisib Umbralisib‡) IDH (Enasidenib Ivosidenib

    Temozolomide

    Temozolomide

    Temozolomide

  • Vincristine

    • Chemical compound; chemotherapy medication

    Entinostat Panobinostat Romidepsin Vorinostat) PIKI (Pi3K) (Alpelisib Copanlisib‡ Duvelisib Idelalisib Inavolisib Umbralisib‡) IDH (Enasidenib Ivosidenib

    Vincristine

    Vincristine

    Vincristine

  • Vusolimogene oderparepvec

    • Medication

    Entinostat Panobinostat Romidepsin Vorinostat) PIKI (Pi3K) (Alpelisib Copanlisib‡ Duvelisib Idelalisib Inavolisib Umbralisib‡) IDH (Enasidenib Ivosidenib

    Vusolimogene oderparepvec

    Vusolimogene_oderparepvec

  • Gemcitabine

    • Chemical compound

    Entinostat Panobinostat Romidepsin Vorinostat) PIKI (Pi3K) (Alpelisib Copanlisib‡ Duvelisib Idelalisib Inavolisib Umbralisib‡) IDH (Enasidenib Ivosidenib

    Gemcitabine

    Gemcitabine

    Gemcitabine

  • Idecabtagene vicleucel

    • Gene therapy medication

    Entinostat Panobinostat Romidepsin Vorinostat) PIKI (Pi3K) (Alpelisib Copanlisib‡ Duvelisib Idelalisib Inavolisib Umbralisib‡) IDH (Enasidenib Ivosidenib

    Idecabtagene vicleucel

    Idecabtagene_vicleucel

  • Nitrogen mustard

    • Family of chemical compounds

    Entinostat Panobinostat Romidepsin Vorinostat) PIKI (Pi3K) (Alpelisib Copanlisib‡ Duvelisib Idelalisib Inavolisib Umbralisib‡) IDH (Enasidenib Ivosidenib

    Nitrogen mustard

    Nitrogen mustard

    Nitrogen_mustard

  • Capecitabine

    • Chemical compound

    Entinostat Panobinostat Romidepsin Vorinostat) PIKI (Pi3K) (Alpelisib Copanlisib‡ Duvelisib Idelalisib Inavolisib Umbralisib‡) IDH (Enasidenib Ivosidenib

    Capecitabine

    Capecitabine

    Capecitabine

  • Oxaliplatin

    • Pharmaceutical drug

    Entinostat Panobinostat Romidepsin Vorinostat) PIKI (Pi3K) (Alpelisib Copanlisib‡ Duvelisib Idelalisib Inavolisib Umbralisib‡) IDH (Enasidenib Ivosidenib

    Oxaliplatin

    Oxaliplatin

    Oxaliplatin

  • Carboplatin

    • Medication used to treat cancer

    Entinostat Panobinostat Romidepsin Vorinostat) PIKI (Pi3K) (Alpelisib Copanlisib‡ Duvelisib Idelalisib Inavolisib Umbralisib‡) IDH (Enasidenib Ivosidenib

    Carboplatin

    Carboplatin

    Carboplatin

  • Tegafur/gimeracil/oteracil

    • Combination drug

    Entinostat Panobinostat Romidepsin Vorinostat) PIKI (Pi3K) (Alpelisib Copanlisib‡ Duvelisib Idelalisib Inavolisib Umbralisib‡) IDH (Enasidenib Ivosidenib

    Tegafur/gimeracil/oteracil

    Tegafur/gimeracil/oteracil

  • Talazoparib

    • Chemical compound

    Entinostat Panobinostat Romidepsin Vorinostat) PIKI (Pi3K) (Alpelisib Copanlisib‡ Duvelisib Idelalisib Inavolisib Umbralisib‡) IDH (Enasidenib Ivosidenib

    Talazoparib

    Talazoparib

    Talazoparib

  • Hydroxycarbamide

    • Medication

    Entinostat Panobinostat Romidepsin Vorinostat) PIKI (Pi3K) (Alpelisib Copanlisib‡ Duvelisib Idelalisib Inavolisib Umbralisib‡) IDH (Enasidenib Ivosidenib

    Hydroxycarbamide

    Hydroxycarbamide

    Hydroxycarbamide

  • Paclitaxel

    • Medication used for cancer

    Entinostat Panobinostat Romidepsin Vorinostat) PIKI (Pi3K) (Alpelisib Copanlisib‡ Duvelisib Idelalisib Inavolisib Umbralisib‡) IDH (Enasidenib Ivosidenib

    Paclitaxel

    Paclitaxel

    Paclitaxel

  • Venetoclax

    • Medication

    Entinostat Panobinostat Romidepsin Vorinostat) PIKI (Pi3K) (Alpelisib Copanlisib‡ Duvelisib Idelalisib Inavolisib Umbralisib‡) IDH (Enasidenib Ivosidenib

    Venetoclax

    Venetoclax

    Venetoclax

  • Mercaptopurine

    • Chemical compound

    Entinostat Panobinostat Romidepsin Vorinostat) PIKI (Pi3K) (Alpelisib Copanlisib‡ Duvelisib Idelalisib Inavolisib Umbralisib‡) IDH (Enasidenib Ivosidenib

    Mercaptopurine

    Mercaptopurine

    Mercaptopurine

  • Darinaparsin

    • Chemical compound

    Entinostat Panobinostat Romidepsin Vorinostat) PIKI (Pi3K) (Alpelisib Copanlisib‡ Duvelisib Idelalisib Inavolisib Umbralisib‡) IDH (Enasidenib Ivosidenib

    Darinaparsin

    Darinaparsin

    Darinaparsin

  • Phosphoinositide 3-kinase

    • Class of enzymes

    idelalisib (July 2014, NDA 206545), the dual PIK3CA and PIK3CD inhibitor copanlisib (September 2017, NDA 209936), and the dual PIK3CD and PIK3CG inhibitor

    Phosphoinositide 3-kinase

    Phosphoinositide 3-kinase

    Phosphoinositide_3-kinase

  • Protein-bound paclitaxel

    • Cancer drug

    Entinostat Panobinostat Romidepsin Vorinostat) PIKI (Pi3K) (Alpelisib Copanlisib‡ Duvelisib Idelalisib Inavolisib Umbralisib‡) IDH (Enasidenib Ivosidenib

    Protein-bound paclitaxel

    Protein-bound_paclitaxel

  • Vinblastine

    • Chemotherapy medication

    Entinostat Panobinostat Romidepsin Vorinostat) PIKI (Pi3K) (Alpelisib Copanlisib‡ Duvelisib Idelalisib Inavolisib Umbralisib‡) IDH (Enasidenib Ivosidenib

    Vinblastine

    Vinblastine

    Vinblastine

  • Brexucabtagene autoleucel

    • Cell based gene therapy

    Entinostat Panobinostat Romidepsin Vorinostat) PIKI (Pi3K) (Alpelisib Copanlisib‡ Duvelisib Idelalisib Inavolisib Umbralisib‡) IDH (Enasidenib Ivosidenib

    Brexucabtagene autoleucel

    Brexucabtagene_autoleucel

  • Platinum-based antineoplastic

    • Chemotherapeutic agents used to treat cancer

    Entinostat Panobinostat Romidepsin Vorinostat) PIKI (Pi3K) (Alpelisib Copanlisib‡ Duvelisib Idelalisib Inavolisib Umbralisib‡) IDH (Enasidenib Ivosidenib

    Platinum-based antineoplastic

    Platinum-based_antineoplastic

  • Lisocabtagene maraleucel

    • Gene therapy medication

    Entinostat Panobinostat Romidepsin Vorinostat) PIKI (Pi3K) (Alpelisib Copanlisib‡ Duvelisib Idelalisib Inavolisib Umbralisib‡) IDH (Enasidenib Ivosidenib

    Lisocabtagene maraleucel

    Lisocabtagene_maraleucel

  • Nadofaragene firadenovec

    • Gene therapy medication

    Entinostat Panobinostat Romidepsin Vorinostat) PIKI (Pi3K) (Alpelisib Copanlisib‡ Duvelisib Idelalisib Inavolisib Umbralisib‡) IDH (Enasidenib Ivosidenib

    Nadofaragene firadenovec

    Nadofaragene_firadenovec

  • Etoposide

    • Chemotherapy medication

    Entinostat Panobinostat Romidepsin Vorinostat) PIKI (Pi3K) (Alpelisib Copanlisib‡ Duvelisib Idelalisib Inavolisib Umbralisib‡) IDH (Enasidenib Ivosidenib

    Etoposide

    Etoposide

    Etoposide

  • Bendamustine

    • Chemical compound

    Entinostat Panobinostat Romidepsin Vorinostat) PIKI (Pi3K) (Alpelisib Copanlisib‡ Duvelisib Idelalisib Inavolisib Umbralisib‡) IDH (Enasidenib Ivosidenib

    Bendamustine

    Bendamustine

    Bendamustine

  • Cytarabine

    • Chemical compound (chemotherapy medication)

    Entinostat Panobinostat Romidepsin Vorinostat) PIKI (Pi3K) (Alpelisib Copanlisib‡ Duvelisib Idelalisib Inavolisib Umbralisib‡) IDH (Enasidenib Ivosidenib

    Cytarabine

    Cytarabine

    Cytarabine

  • Melphalan

    • Chemical compound

    Entinostat Panobinostat Romidepsin Vorinostat) PIKI (Pi3K) (Alpelisib Copanlisib‡ Duvelisib Idelalisib Inavolisib Umbralisib‡) IDH (Enasidenib Ivosidenib

    Melphalan

    Melphalan

    Melphalan

  • Antimetabolite

    • Chemical that inhibits the use of a metabolite

    Entinostat Panobinostat Romidepsin Vorinostat) PIKI (Pi3K) (Alpelisib Copanlisib‡ Duvelisib Idelalisib Inavolisib Umbralisib‡) IDH (Enasidenib Ivosidenib

    Antimetabolite

    Antimetabolite

    Antimetabolite

  • Lifileucel

    • Medication

    Entinostat Panobinostat Romidepsin Vorinostat) PIKI (Pi3K) (Alpelisib Copanlisib‡ Duvelisib Idelalisib Inavolisib Umbralisib‡) IDH (Enasidenib Ivosidenib

    Lifileucel

    Lifileucel

  • Bexarotene

    • Chemical compound

    Entinostat Panobinostat Romidepsin Vorinostat) PIKI (Pi3K) (Alpelisib Copanlisib‡ Duvelisib Idelalisib Inavolisib Umbralisib‡) IDH (Enasidenib Ivosidenib

    Bexarotene

    Bexarotene

    Bexarotene

  • Azacitidine

    • Chemical compound

    Entinostat Panobinostat Romidepsin Vorinostat) PIKI (Pi3K) (Alpelisib Copanlisib‡ Duvelisib Idelalisib Inavolisib Umbralisib‡) IDH (Enasidenib Ivosidenib

    Azacitidine

    Azacitidine

    Azacitidine

  • Idelalisib

    • Chemical compound

    lymphoma: duvelisib in December 2021, umbralisib in January 2022, and copanlisib in November 2023. These withdrawals are attributed to a possibly detrimental

    Idelalisib

    Idelalisib

    Idelalisib

  • Dactinomycin

    • Chemical compound

    Entinostat Panobinostat Romidepsin Vorinostat) PIKI (Pi3K) (Alpelisib Copanlisib‡ Duvelisib Idelalisib Inavolisib Umbralisib‡) IDH (Enasidenib Ivosidenib

    Dactinomycin

    Dactinomycin

    Dactinomycin

  • Olaparib

    • Chemical compound (cancer therapy drug)

    Entinostat Panobinostat Romidepsin Vorinostat) PIKI (Pi3K) (Alpelisib Copanlisib‡ Duvelisib Idelalisib Inavolisib Umbralisib‡) IDH (Enasidenib Ivosidenib

    Olaparib

    Olaparib

    Olaparib

  • Tebentafusp

    • Pharmaceutical drug

    Entinostat Panobinostat Romidepsin Vorinostat) PIKI (Pi3K) (Alpelisib Copanlisib‡ Duvelisib Idelalisib Inavolisib Umbralisib‡) IDH (Enasidenib Ivosidenib

    Tebentafusp

    Tebentafusp

  • FOLFIRI

    • Chemotherapy regimen for colorectal cancer treatment

    Entinostat Panobinostat Romidepsin Vorinostat) PIKI (Pi3K) (Alpelisib Copanlisib‡ Duvelisib Idelalisib Inavolisib Umbralisib‡) IDH (Enasidenib Ivosidenib

    FOLFIRI

    FOLFIRI

  • Ciltacabtagene autoleucel

    • Gene therapy medication used to treat multiple myeloma

    Entinostat Panobinostat Romidepsin Vorinostat) PIKI (Pi3K) (Alpelisib Copanlisib‡ Duvelisib Idelalisib Inavolisib Umbralisib‡) IDH (Enasidenib Ivosidenib

    Ciltacabtagene autoleucel

    Ciltacabtagene_autoleucel

  • Ifosfamide

    • Chemotherapy medication

    Entinostat Panobinostat Romidepsin Vorinostat) PIKI (Pi3K) (Alpelisib Copanlisib‡ Duvelisib Idelalisib Inavolisib Umbralisib‡) IDH (Enasidenib Ivosidenib

    Ifosfamide

    Ifosfamide

    Ifosfamide

  • Anthracycline

    • Class of antibiotics

    Entinostat Panobinostat Romidepsin Vorinostat) PIKI (Pi3K) (Alpelisib Copanlisib‡ Duvelisib Idelalisib Inavolisib Umbralisib‡) IDH (Enasidenib Ivosidenib

    Anthracycline

    Anthracycline

    Anthracycline

  • Asparaginase

    • Enzyme used as medication and in food manufacturing

    Entinostat Panobinostat Romidepsin Vorinostat) PIKI (Pi3K) (Alpelisib Copanlisib‡ Duvelisib Idelalisib Inavolisib Umbralisib‡) IDH (Enasidenib Ivosidenib

    Asparaginase

    Asparaginase

    Asparaginase

  • Docetaxel

    • Chemotherapy medication

    Entinostat Panobinostat Romidepsin Vorinostat) PIKI (Pi3K) (Alpelisib Copanlisib‡ Duvelisib Idelalisib Inavolisib Umbralisib‡) IDH (Enasidenib Ivosidenib

    Docetaxel

    Docetaxel

    Docetaxel

  • Trabectedin

    • Chemical compound

    Entinostat Panobinostat Romidepsin Vorinostat) PIKI (Pi3K) (Alpelisib Copanlisib‡ Duvelisib Idelalisib Inavolisib Umbralisib‡) IDH (Enasidenib Ivosidenib

    Trabectedin

    Trabectedin

    Trabectedin

  • Obecabtagene autoleucel

    • Gene therapy medication

    Entinostat Panobinostat Romidepsin Vorinostat) PIKI (Pi3K) (Alpelisib Copanlisib‡ Duvelisib Idelalisib Inavolisib Umbralisib‡) IDH (Enasidenib Ivosidenib

    Obecabtagene autoleucel

    Obecabtagene_autoleucel

  • Daunorubicin

    • Chemotherapy medication

    Entinostat Panobinostat Romidepsin Vorinostat) PIKI (Pi3K) (Alpelisib Copanlisib‡ Duvelisib Idelalisib Inavolisib Umbralisib‡) IDH (Enasidenib Ivosidenib

    Daunorubicin

    Daunorubicin

    Daunorubicin

  • Pelabresib

    • Investigational oral small-molecule drug

    Entinostat Panobinostat Romidepsin Vorinostat) PIKI (Pi3K) (Alpelisib Copanlisib‡ Duvelisib Idelalisib Inavolisib Umbralisib‡) IDH (Enasidenib Ivosidenib

    Pelabresib

    Pelabresib

    Pelabresib

  • Follicular lymphoma

    • Cancer originating in lymph nodes

    treatment failures include: 1) Phosphoinositide 3-kinase inhibitors such as copanlisib, duvelisib, and idelalisib which block the phosphoinositide 3-kinase signaling

    Follicular lymphoma

    Follicular lymphoma

    Follicular_lymphoma

  • Mitomycin C

    • Chemical compound

    Entinostat Panobinostat Romidepsin Vorinostat) PIKI (Pi3K) (Alpelisib Copanlisib‡ Duvelisib Idelalisib Inavolisib Umbralisib‡) IDH (Enasidenib Ivosidenib

    Mitomycin C

    Mitomycin C

    Mitomycin_C

  • Calaspargase pegol

    • Pharmaceutical medication

    Entinostat Panobinostat Romidepsin Vorinostat) PIKI (Pi3K) (Alpelisib Copanlisib‡ Duvelisib Idelalisib Inavolisib Umbralisib‡) IDH (Enasidenib Ivosidenib

    Calaspargase pegol

    Calaspargase_pegol

  • Aminolevulinic acid

    • Endogenous non-proteinogenic amino acid

    Entinostat Panobinostat Romidepsin Vorinostat) PIKI (Pi3K) (Alpelisib Copanlisib‡ Duvelisib Idelalisib Inavolisib Umbralisib‡) IDH (Enasidenib Ivosidenib

    Aminolevulinic acid

    Aminolevulinic acid

    Aminolevulinic_acid

  • Bortezomib

    • Chemical compound

    Entinostat Panobinostat Romidepsin Vorinostat) PIKI (Pi3K) (Alpelisib Copanlisib‡ Duvelisib Idelalisib Inavolisib Umbralisib‡) IDH (Enasidenib Ivosidenib

    Bortezomib

    Bortezomib

    Bortezomib

  • Dordaviprone

    • Chemical compound

    Entinostat Panobinostat Romidepsin Vorinostat) PIKI (Pi3K) (Alpelisib Copanlisib‡ Duvelisib Idelalisib Inavolisib Umbralisib‡) IDH (Enasidenib Ivosidenib

    Dordaviprone

    Dordaviprone

    Dordaviprone

  • Decitabine/cedazuridine

    • Medication

    Entinostat Panobinostat Romidepsin Vorinostat) PIKI (Pi3K) (Alpelisib Copanlisib‡ Duvelisib Idelalisib Inavolisib Umbralisib‡) IDH (Enasidenib Ivosidenib

    Decitabine/cedazuridine

    Decitabine/cedazuridine

    Decitabine/cedazuridine

  • Irinotecan

    • Cancer medication

    Entinostat Panobinostat Romidepsin Vorinostat) PIKI (Pi3K) (Alpelisib Copanlisib‡ Duvelisib Idelalisib Inavolisib Umbralisib‡) IDH (Enasidenib Ivosidenib

    Irinotecan

    Irinotecan

    Irinotecan

  • Divarasib

    • Experimental cancer drug

    Entinostat Panobinostat Romidepsin Vorinostat) PIKI (Pi3K) (Alpelisib Copanlisib‡ Duvelisib Idelalisib Inavolisib Umbralisib‡) IDH (Enasidenib Ivosidenib

    Divarasib

    Divarasib

    Divarasib

  • Navitoclax

    • Chemical compound

    Entinostat Panobinostat Romidepsin Vorinostat) PIKI (Pi3K) (Alpelisib Copanlisib‡ Duvelisib Idelalisib Inavolisib Umbralisib‡) IDH (Enasidenib Ivosidenib

    Navitoclax

    Navitoclax

    Navitoclax

  • Chemotherapy regimen

    • Regimen commonly used in chemotherapy

    Entinostat Panobinostat Romidepsin Vorinostat) PIKI (Pi3K) (Alpelisib Copanlisib‡ Duvelisib Idelalisib Inavolisib Umbralisib‡) IDH (Enasidenib Ivosidenib

    Chemotherapy regimen

    Chemotherapy_regimen

  • Imetelstat

    • Medication

    Entinostat Panobinostat Romidepsin Vorinostat) PIKI (Pi3K) (Alpelisib Copanlisib‡ Duvelisib Idelalisib Inavolisib Umbralisib‡) IDH (Enasidenib Ivosidenib

    Imetelstat

    Imetelstat

    Imetelstat

  • Lurbinectedin

    • Chemical compound

    Entinostat Panobinostat Romidepsin Vorinostat) PIKI (Pi3K) (Alpelisib Copanlisib‡ Duvelisib Idelalisib Inavolisib Umbralisib‡) IDH (Enasidenib Ivosidenib

    Lurbinectedin

    Lurbinectedin

    Lurbinectedin

  • Photodynamic therapy

    • Form of phototherapy

    Entinostat Panobinostat Romidepsin Vorinostat) PIKI (Pi3K) (Alpelisib Copanlisib‡ Duvelisib Idelalisib Inavolisib Umbralisib‡) IDH (Enasidenib Ivosidenib

    Photodynamic therapy

    Photodynamic therapy

    Photodynamic_therapy

  • Cancer immunotherapy

    • Artificial stimulation of the immune system to treat cancer

    Entinostat Panobinostat Romidepsin Vorinostat) PIKI (Pi3K) (Alpelisib Copanlisib‡ Duvelisib Idelalisib Inavolisib Umbralisib‡) IDH (Enasidenib Ivosidenib

    Cancer immunotherapy

    Cancer immunotherapy

    Cancer_immunotherapy

  • Elranatamab

    • Medication

    Trilaciclib KRAS inhibitors Adagrasib Sotorasib Pi3K inhibitors Alpelisib Copanlisib Duvelisib Idelalisib Inavolisib Parsaclisib Menin inhibitors Revumenib

    Elranatamab

    Elranatamab

  • Antineoplastic

    • Class of drugs used to treat malignant tumors

    Entinostat Panobinostat Romidepsin Vorinostat) PIKI (Pi3K) (Alpelisib Copanlisib‡ Duvelisib Idelalisib Inavolisib Umbralisib‡) IDH (Enasidenib Ivosidenib

    Antineoplastic

    Antineoplastic

    Antineoplastic

  • Abemaciclib

    • Anti-breast cancer medication

    Entinostat Panobinostat Romidepsin Vorinostat) PIKI (Pi3K) (Alpelisib Copanlisib‡ Duvelisib Idelalisib Inavolisib Umbralisib‡) IDH (Enasidenib Ivosidenib

    Abemaciclib

    Abemaciclib

    Abemaciclib

  • Protein kinase inhibitor

    • Enzymes that block actions of protein kinases

    Entinostat Panobinostat Romidepsin Vorinostat) PIKI (Pi3K) (Alpelisib Copanlisib‡ Duvelisib Idelalisib Inavolisib Umbralisib‡) IDH (Enasidenib Ivosidenib

    Protein kinase inhibitor

    Protein_kinase_inhibitor

  • Procarbazine

    • Chemotherapy medication used for several cancer types

    Entinostat Panobinostat Romidepsin Vorinostat) PIKI (Pi3K) (Alpelisib Copanlisib‡ Duvelisib Idelalisib Inavolisib Umbralisib‡) IDH (Enasidenib Ivosidenib

    Procarbazine

    Procarbazine

    Procarbazine

  • Pemetrexed

    • Chemical compound

    Entinostat Panobinostat Romidepsin Vorinostat) PIKI (Pi3K) (Alpelisib Copanlisib‡ Duvelisib Idelalisib Inavolisib Umbralisib‡) IDH (Enasidenib Ivosidenib

    Pemetrexed

    Pemetrexed

    Pemetrexed

  • Camptothecin

    • Chemical compound

    Entinostat Panobinostat Romidepsin Vorinostat) PIKI (Pi3K) (Alpelisib Copanlisib‡ Duvelisib Idelalisib Inavolisib Umbralisib‡) IDH (Enasidenib Ivosidenib

    Camptothecin

    Camptothecin

    Camptothecin

  • Ribociclib

    • Chemical compound

    Entinostat Panobinostat Romidepsin Vorinostat) PIKI (Pi3K) (Alpelisib Copanlisib‡ Duvelisib Idelalisib Inavolisib Umbralisib‡) IDH (Enasidenib Ivosidenib

    Ribociclib

    Ribociclib

    Ribociclib

  • Taxane

    • Chemical compound

    Entinostat Panobinostat Romidepsin Vorinostat) PIKI (Pi3K) (Alpelisib Copanlisib‡ Duvelisib Idelalisib Inavolisib Umbralisib‡) IDH (Enasidenib Ivosidenib

    Taxane

    Taxane

    Taxane

  • High-dose chemotherapy

    • Entinostat Panobinostat Romidepsin Vorinostat) PIKI (Pi3K) (Alpelisib Copanlisib‡ Duvelisib Idelalisib Inavolisib Umbralisib‡) IDH (Enasidenib Ivosidenib

    High-dose chemotherapy

    High-dose chemotherapy

    High-dose_chemotherapy

  • Tisagenlecleucel

    • Gene therapy medication

    Entinostat Panobinostat Romidepsin Vorinostat) PIKI (Pi3K) (Alpelisib Copanlisib‡ Duvelisib Idelalisib Inavolisib Umbralisib‡) IDH (Enasidenib Ivosidenib

    Tisagenlecleucel

    Tisagenlecleucel

  • Eflornithine

    • Chemical compound

    Entinostat Panobinostat Romidepsin Vorinostat) PIKI (Pi3K) (Alpelisib Copanlisib‡ Duvelisib Idelalisib Inavolisib Umbralisib‡) IDH (Enasidenib Ivosidenib

    Eflornithine

    Eflornithine

    Eflornithine

  • Diflomotecan

    • Chemical compound

    Entinostat Panobinostat Romidepsin Vorinostat) PIKI (Pi3K) (Alpelisib Copanlisib‡ Duvelisib Idelalisib Inavolisib Umbralisib‡) IDH (Enasidenib Ivosidenib

    Diflomotecan

    Diflomotecan

    Diflomotecan

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