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Chemical compound
Melphalan, sold under the brand name Alkeran among others, is a chemotherapy medication used to treat multiple myeloma; malignant lymphoma; lymphoblastic
Melphalan
Alkylating type cancer drug
Melphalan flufenamide is a medication used to treat refractory multiple myeloma. Known as melflufen, it is available in multiple Euopean countries, but
Melphalan_flufenamide
Cancer of plasma cells
transplantation. For these people, the standard of care has been chemotherapy with melphalan and prednisone. Recent studies among this population suggest improved
Multiple_myeloma
Chemical compound
bortezomib plus lenalidomide plus dexamethasone as well as bortezomib plus melphalan and prednisone may result in a large increase in the progression-free
Bortezomib
Immunomodulatory drug
treatment for multiple myeloma in combination with dexamethasone or with melphalan and prednisone to treat acute episodes of erythema nodosum leprosum, as
Thalidomide
Protocol Assessment from the Food and Drug Administration for its use of melphalan in treating unresectable liver tumors. PHP, also known as the Delcath
Delcath_Systems
Drugs that are useful against cancer
Chlorozotocin Cyclophosphamide Dacarbazine Fotemustine Ifosfamide Lomustine Melphalan Melphalan flufenamide Mitobronitol Nimustine Nitrosoureas Pipobroman Ranimustine
List of chemotherapeutic agents
List_of_chemotherapeutic_agents
Pharmaceutical drug classification
L01AA03 Melphalan L01AA05 Chlormethine L01AA06 Ifosfamide L01AA07 Trofosfamide L01AA08 Prednimustine L01AA09 Bendamustine L01AA10 Melphalan flufenamide
ATC_code_L01
Pharmaceutical drugs
longer time than some of the other alkylating agents. Examples include melphalan and chlorambucil. The following three groups are almost always considered
Alkylating antineoplastic agent
Alkylating_antineoplastic_agent
Family of chemical compounds
developed from mustine include cyclophosphamide, chlorambucil, uramustine, melphalan, and bendamustine. Nitrogen mustards that can be used for chemical warfare
Nitrogen_mustard
Monoclonal antibody
daratumumab for use in combination with bortezomib (also termed Velcade), melphalan and prednisone to include the treatment of people with newly diagnosed
Daratumumab
Chemotherapy medication
Chlormethine Cyclophosphamide# (Ifosfamide# Trofosfamide) Chlorambucil# Melphalan (Melphalan flufenamide) Prednimustine Uramustine Nitrosoureas: Carmustine Fotemustine
Doxorubicin
Medical condition
oral mucositis is the most common and most debilitating, especially when melphalan is used. In grade 3 oral mucositis, the patient is unable to eat solid
Mucositis
Paraneoplastic syndrome
such as melphalan. Dosage regimens are selected on the basis of patient tolerance. Hematological response rates to the dexamethasone/melphalan regimens
POEMS_syndrome
Investigational oral small-molecule drug
Chlormethine Cyclophosphamide# (Ifosfamide# Trofosfamide) Chlorambucil# Melphalan (Melphalan flufenamide) Prednimustine Uramustine Nitrosoureas: Carmustine Fotemustine
Pelabresib
Medication used as chemotherapy and to suppress the immune system
It appears to be an alternative to the more traditional treatment with melphalan in people who are ill-suited for autologous stem cell transplant. Graft-versus-host
Cyclophosphamide
Chemical compound
the recipient. Use under this protocol, usually with fludarabine and melphalan, was developed by oncologists at the University of Texas MD Anderson Cancer
Carmustine
Medical condition
associated with improved outcomes. CyBorD may be used alone, or bortezomib–melphalan–dexamethasone may be used in resource limited settings where daratumumab
AL_amyloidosis
Chemical compound
In Japan, a widely used regimen consisting of high-dose thiotepa and melphalan, followed by autologous peripheral blood stem cell rescue, is used to
Thiotepa
Chemotherapy medication
Chlormethine Cyclophosphamide# (Ifosfamide# Trofosfamide) Chlorambucil# Melphalan (Melphalan flufenamide) Prednimustine Uramustine Nitrosoureas: Carmustine Fotemustine
Fluorouracil
Chemical compound
Chlormethine Cyclophosphamide# (Ifosfamide# Trofosfamide) Chlorambucil# Melphalan (Melphalan flufenamide) Prednimustine Uramustine Nitrosoureas: Carmustine Fotemustine
Carfilzomib
Chemical compound
Chlormethine Cyclophosphamide# (Ifosfamide# Trofosfamide) Chlorambucil# Melphalan (Melphalan flufenamide) Prednimustine Uramustine Nitrosoureas: Carmustine Fotemustine
Mafosfamide
Cancer medication
Chlormethine Cyclophosphamide# (Ifosfamide# Trofosfamide) Chlorambucil# Melphalan (Melphalan flufenamide) Prednimustine Uramustine Nitrosoureas: Carmustine Fotemustine
Temozolomide
Male reproductive cell
sperm cell-derived chromosomal aberrations. Treatment of male mice with melphalan, a bifunctional alkylating agent frequently employed in chemotherapy,
Sperm
Medication
Chlormethine Cyclophosphamide# (Ifosfamide# Trofosfamide) Chlorambucil# Melphalan (Melphalan flufenamide) Prednimustine Uramustine Nitrosoureas: Carmustine Fotemustine
Tretinoin
Glycopeptide antibiotic used to treat various cancers
Chlormethine Cyclophosphamide# (Ifosfamide# Trofosfamide) Chlorambucil# Melphalan (Melphalan flufenamide) Prednimustine Uramustine Nitrosoureas: Carmustine Fotemustine
Bleomycin
Class of chemical compounds
Chlormethine Cyclophosphamide# (Ifosfamide# Trofosfamide) Chlorambucil# Melphalan (Melphalan flufenamide) Prednimustine Uramustine Nitrosoureas: Carmustine Fotemustine
Indolocarbazole
List of drugs given to treat leukemia
Gemtuzumab ozogamicin Idarubicin Imatinib mesylate Interferon-α Interleukin-2 Melphalan Methotrexate Mitoxantrone Nelarabine Nilotinib Oblimersen Pegaspargase
List_of_antileukemic_drugs
Medical condition
abnormal cells that are producing them. Chemotherapeutic agents such as melphalan or bortezomib can be used to kill off the abnormal cell line that is producing
Cardiac_amyloidosis
Treatment of cancer using drugs that inhibit cell division or kill cells
agents. Nitrogen mustards include mechlorethamine, cyclophosphamide, melphalan, chlorambucil, ifosfamide and busulfan. Nitrosoureas include N-Nitroso-N-methylurea
Chemotherapy
Chemical compound
Chlormethine Cyclophosphamide# (Ifosfamide# Trofosfamide) Chlorambucil# Melphalan (Melphalan flufenamide) Prednimustine Uramustine Nitrosoureas: Carmustine Fotemustine
Lomustine
Medication used to treat cancer
Chlormethine Cyclophosphamide# (Ifosfamide# Trofosfamide) Chlorambucil# Melphalan (Melphalan flufenamide) Prednimustine Uramustine Nitrosoureas: Carmustine Fotemustine
Carboplatin
Pharmaceutical drug
Chlormethine Cyclophosphamide# (Ifosfamide# Trofosfamide) Chlorambucil# Melphalan (Melphalan flufenamide) Prednimustine Uramustine Nitrosoureas: Carmustine Fotemustine
Cladribine
Nitrogen mustard used as a chemotherapy agent
Chlormethine Cyclophosphamide# (Ifosfamide# Trofosfamide) Chlorambucil# Melphalan (Melphalan flufenamide) Prednimustine Uramustine Nitrosoureas: Carmustine Fotemustine
Normustine
American biopharmaceutical company
Brand Name Drug Name(s) Indication Date Approved (USA) Partner Alkeran melphalan palliative treatment of multiple myeloma and for the palliation of non-resectable
Celgene
Chemical compound
Chlormethine Cyclophosphamide# (Ifosfamide# Trofosfamide) Chlorambucil# Melphalan (Melphalan flufenamide) Prednimustine Uramustine Nitrosoureas: Carmustine Fotemustine
Azacitidine
Genetically inherited cancer of certain nerve tissues
(cisplatin, carboplatin), alkylating agents (cyclophosphamide, ifosfamide, melphalan), topoisomerase II inhibitor (etoposide), anthracycline antibiotics (doxorubicin)
Neuroblastoma
Chemical compound
Chlormethine Cyclophosphamide# (Ifosfamide# Trofosfamide) Chlorambucil# Melphalan (Melphalan flufenamide) Prednimustine Uramustine Nitrosoureas: Carmustine Fotemustine
Pentostatin
Chemical compound and pharmaceutical drug
Chlormethine Cyclophosphamide# (Ifosfamide# Trofosfamide) Chlorambucil# Melphalan (Melphalan flufenamide) Prednimustine Uramustine Nitrosoureas: Carmustine Fotemustine
Cisplatin
Chemical compound
Chlormethine Cyclophosphamide# (Ifosfamide# Trofosfamide) Chlorambucil# Melphalan (Melphalan flufenamide) Prednimustine Uramustine Nitrosoureas: Carmustine Fotemustine
Nirogacestat
Pair of enantiomers
received thalidomide or lenalidomide in conjunction with dexamethasone, melphalan, or doxorubicin. In March 2008, the US Food and Drug Administration (FDA)
Lenalidomide
Chemical compound
Chlormethine Cyclophosphamide# (Ifosfamide# Trofosfamide) Chlorambucil# Melphalan (Melphalan flufenamide) Prednimustine Uramustine Nitrosoureas: Carmustine Fotemustine
Gemcitabine
Medication
Chlormethine Cyclophosphamide# (Ifosfamide# Trofosfamide) Chlorambucil# Melphalan (Melphalan flufenamide) Prednimustine Uramustine Nitrosoureas: Carmustine Fotemustine
Imetelstat
Metabolic disease involving abnormal deposited amyloid proteins
on the type of amyloidosis that is present. Treatment with high dose melphalan, a chemotherapy agent, followed by stem cell transplantation has shown
Amyloidosis
Chemical compound
Chlormethine Cyclophosphamide# (Ifosfamide# Trofosfamide) Chlorambucil# Melphalan (Melphalan flufenamide) Prednimustine Uramustine Nitrosoureas: Carmustine Fotemustine
Bisantrene
Chemical compound
Chlormethine Cyclophosphamide# (Ifosfamide# Trofosfamide) Chlorambucil# Melphalan (Melphalan flufenamide) Prednimustine Uramustine Nitrosoureas: Carmustine Fotemustine
Rucaparib
Chemotherapy and immunosuppressant medication
Chlormethine Cyclophosphamide# (Ifosfamide# Trofosfamide) Chlorambucil# Melphalan (Melphalan flufenamide) Prednimustine Uramustine Nitrosoureas: Carmustine Fotemustine
Methotrexate
Chemical compound
parasites to oxidative antiparasitic drugs. Defty, CL; Marsden, JR (2012). "Melphalan in regional chemotherapy for locally recurrent metastatic melanoma". Current
Buthionine_sulfoximine
Major pharmaceutical company in South Africa
from the United States. In 2009, Aspen purchased the rights to market Melphalan and several other cancer drugs from GSK, such as levothyroxine, azathioprine
Aspen_Pharmacare
Chemical compound; chemotherapy medication
Chlormethine Cyclophosphamide# (Ifosfamide# Trofosfamide) Chlorambucil# Melphalan (Melphalan flufenamide) Prednimustine Uramustine Nitrosoureas: Carmustine Fotemustine
Vincristine
Chemical compound
Chlormethine Cyclophosphamide# (Ifosfamide# Trofosfamide) Chlorambucil# Melphalan (Melphalan flufenamide) Prednimustine Uramustine Nitrosoureas: Carmustine Fotemustine
Copanlisib
Chemical compound
Chlormethine Cyclophosphamide# (Ifosfamide# Trofosfamide) Chlorambucil# Melphalan (Melphalan flufenamide) Prednimustine Uramustine Nitrosoureas: Carmustine Fotemustine
Nedaplatin
Chemical compound
Chlormethine Cyclophosphamide# (Ifosfamide# Trofosfamide) Chlorambucil# Melphalan (Melphalan flufenamide) Prednimustine Uramustine Nitrosoureas: Carmustine Fotemustine
Menogaril
Medication
Chlormethine Cyclophosphamide# (Ifosfamide# Trofosfamide) Chlorambucil# Melphalan (Melphalan flufenamide) Prednimustine Uramustine Nitrosoureas: Carmustine Fotemustine
Adagrasib
Chemical compound
Chlormethine Cyclophosphamide# (Ifosfamide# Trofosfamide) Chlorambucil# Melphalan (Melphalan flufenamide) Prednimustine Uramustine Nitrosoureas: Carmustine Fotemustine
Satraplatin
Chemical compound
Chlormethine Cyclophosphamide# (Ifosfamide# Trofosfamide) Chlorambucil# Melphalan (Melphalan flufenamide) Prednimustine Uramustine Nitrosoureas: Carmustine Fotemustine
Ixazomib
Industrial chemical and medication
Chlormethine Cyclophosphamide# (Ifosfamide# Trofosfamide) Chlorambucil# Melphalan (Melphalan flufenamide) Prednimustine Uramustine Nitrosoureas: Carmustine Fotemustine
Arsenic_trioxide
Medication
Chlormethine Cyclophosphamide# (Ifosfamide# Trofosfamide) Chlorambucil# Melphalan (Melphalan flufenamide) Prednimustine Uramustine Nitrosoureas: Carmustine Fotemustine
Venetoclax
Chemical compound
Chlormethine Cyclophosphamide# (Ifosfamide# Trofosfamide) Chlorambucil# Melphalan (Melphalan flufenamide) Prednimustine Uramustine Nitrosoureas: Carmustine Fotemustine
Alitretinoin
Anti-cancer medication
Chlormethine Cyclophosphamide# (Ifosfamide# Trofosfamide) Chlorambucil# Melphalan (Melphalan flufenamide) Prednimustine Uramustine Nitrosoureas: Carmustine Fotemustine
Vorasidenib
Winners of satirical science award
Emilian (18 November 2021). "Ice-cream used as cryotherapy during high-dose melphalan conditioning reduces oral mucositis after autologous hematopoietic stem
List of Ig Nobel Prize winners
List_of_Ig_Nobel_Prize_winners
Cell based gene therapy
Chlormethine Cyclophosphamide# (Ifosfamide# Trofosfamide) Chlorambucil# Melphalan (Melphalan flufenamide) Prednimustine Uramustine Nitrosoureas: Carmustine Fotemustine
Brexucabtagene_autoleucel
Gene therapy medication
Chlormethine Cyclophosphamide# (Ifosfamide# Trofosfamide) Chlorambucil# Melphalan (Melphalan flufenamide) Prednimustine Uramustine Nitrosoureas: Carmustine Fotemustine
Lisocabtagene_maraleucel
Nonsteroidal anti-inflammatory medication
Chlormethine Cyclophosphamide# (Ifosfamide# Trofosfamide) Chlorambucil# Melphalan (Melphalan flufenamide) Prednimustine Uramustine Nitrosoureas: Carmustine Fotemustine
Celecoxib
Irregular beating of the atria of the heart
ibuprofen), bisphosphonates, and other chemotherapeutic agents such as melphalan, interleukin-2, and anthracyclines. Other medications that rarely increase
Atrial_fibrillation
Cancer drug
Chlormethine Cyclophosphamide# (Ifosfamide# Trofosfamide) Chlorambucil# Melphalan (Melphalan flufenamide) Prednimustine Uramustine Nitrosoureas: Carmustine Fotemustine
Protein-bound_paclitaxel
Medical drug glass
Chlormethine Cyclophosphamide# (Ifosfamide# Trofosfamide) Chlorambucil# Melphalan (Melphalan flufenamide) Prednimustine Uramustine Nitrosoureas: Carmustine Fotemustine
Phosphoinositide 3-kinase inhibitor
Phosphoinositide_3-kinase_inhibitor
Medical condition
condition. It has been reported that clearance of lesions can be done with melphalan and cyclophosphamide alone or in combination with prednisone. Both isotretinoin
Papular_mucinosis
Chemical compound
Chlormethine Cyclophosphamide# (Ifosfamide# Trofosfamide) Chlorambucil# Melphalan (Melphalan flufenamide) Prednimustine Uramustine Nitrosoureas: Carmustine Fotemustine
Semustine
Gene therapy medication
Chlormethine Cyclophosphamide# (Ifosfamide# Trofosfamide) Chlorambucil# Melphalan (Melphalan flufenamide) Prednimustine Uramustine Nitrosoureas: Carmustine Fotemustine
Idecabtagene_vicleucel
Chemical compound
Chlormethine Cyclophosphamide# (Ifosfamide# Trofosfamide) Chlorambucil# Melphalan (Melphalan flufenamide) Prednimustine Uramustine Nitrosoureas: Carmustine Fotemustine
Talazoparib
Gene therapy medication
Chlormethine Cyclophosphamide# (Ifosfamide# Trofosfamide) Chlorambucil# Melphalan (Melphalan flufenamide) Prednimustine Uramustine Nitrosoureas: Carmustine Fotemustine
Obecabtagene_autoleucel
Protein-coding gene in the species Homo sapiens
such as those formed by chemotherapy drugs cisplatin, mitomycin c and melphalan. Within the Fanconi anemia core complex, FANCB has an obligate interaction
Fanconi anemia group B protein
Fanconi_anemia_group_B_protein
Glycopeptide antibiotic used to treat various cancers
Chlormethine Cyclophosphamide# (Ifosfamide# Trofosfamide) Chlorambucil# Melphalan (Melphalan flufenamide) Prednimustine Uramustine Nitrosoureas: Carmustine Fotemustine
Pingyangmycin
Chemical compound
Chlormethine Cyclophosphamide# (Ifosfamide# Trofosfamide) Chlorambucil# Melphalan (Melphalan flufenamide) Prednimustine Uramustine Nitrosoureas: Carmustine Fotemustine
Navitoclax
Pharmaceutical drug
Chlormethine Cyclophosphamide# (Ifosfamide# Trofosfamide) Chlorambucil# Melphalan (Melphalan flufenamide) Prednimustine Uramustine Nitrosoureas: Carmustine Fotemustine
Oxaliplatin
Chemical compound
Chlormethine Cyclophosphamide# (Ifosfamide# Trofosfamide) Chlorambucil# Melphalan (Melphalan flufenamide) Prednimustine Uramustine Nitrosoureas: Carmustine Fotemustine
Taxane
Chemical compound
Chlormethine Cyclophosphamide# (Ifosfamide# Trofosfamide) Chlorambucil# Melphalan (Melphalan flufenamide) Prednimustine Uramustine Nitrosoureas: Carmustine Fotemustine
Vepdegestrant
Chemical that inhibits the use of a metabolite
Chlormethine Cyclophosphamide# (Ifosfamide# Trofosfamide) Chlorambucil# Melphalan (Melphalan flufenamide) Prednimustine Uramustine Nitrosoureas: Carmustine Fotemustine
Antimetabolite
Chemotherapy regimen for colorectal cancer treatment
Chlormethine Cyclophosphamide# (Ifosfamide# Trofosfamide) Chlorambucil# Melphalan (Melphalan flufenamide) Prednimustine Uramustine Nitrosoureas: Carmustine Fotemustine
FOLFIRI
Chemical compound
Chlormethine Cyclophosphamide# (Ifosfamide# Trofosfamide) Chlorambucil# Melphalan (Melphalan flufenamide) Prednimustine Uramustine Nitrosoureas: Carmustine Fotemustine
Dactinomycin
Anticancer drug
Chlormethine Cyclophosphamide# (Ifosfamide# Trofosfamide) Chlorambucil# Melphalan (Melphalan flufenamide) Prednimustine Uramustine Nitrosoureas: Carmustine Fotemustine
Olutasidenib
Enzymes that block actions of protein kinases
Chlormethine Cyclophosphamide# (Ifosfamide# Trofosfamide) Chlorambucil# Melphalan (Melphalan flufenamide) Prednimustine Uramustine Nitrosoureas: Carmustine Fotemustine
Protein_kinase_inhibitor
Chlormethine Cyclophosphamide# (Ifosfamide# Trofosfamide) Chlorambucil# Melphalan (Melphalan flufenamide) Prednimustine Uramustine Nitrosoureas: Carmustine Fotemustine
MOPP_(chemotherapy)
Chemical compound
Chlormethine Cyclophosphamide# (Ifosfamide# Trofosfamide) Chlorambucil# Melphalan (Melphalan flufenamide) Prednimustine Uramustine Nitrosoureas: Carmustine Fotemustine
Dordaviprone
Gene therapy medication used to treat multiple myeloma
Chlormethine Cyclophosphamide# (Ifosfamide# Trofosfamide) Chlorambucil# Melphalan (Melphalan flufenamide) Prednimustine Uramustine Nitrosoureas: Carmustine Fotemustine
Ciltacabtagene_autoleucel
Medication
Chlormethine Cyclophosphamide# (Ifosfamide# Trofosfamide) Chlorambucil# Melphalan (Melphalan flufenamide) Prednimustine Uramustine Nitrosoureas: Carmustine Fotemustine
Lifileucel
Medication
Chlormethine Cyclophosphamide# (Ifosfamide# Trofosfamide) Chlorambucil# Melphalan (Melphalan flufenamide) Prednimustine Uramustine Nitrosoureas: Carmustine Fotemustine
Vusolimogene_oderparepvec
Experimental cancer drug
Chlormethine Cyclophosphamide# (Ifosfamide# Trofosfamide) Chlorambucil# Melphalan (Melphalan flufenamide) Prednimustine Uramustine Nitrosoureas: Carmustine Fotemustine
Divarasib
Enzyme used as medication and in food manufacturing
Chlormethine Cyclophosphamide# (Ifosfamide# Trofosfamide) Chlorambucil# Melphalan (Melphalan flufenamide) Prednimustine Uramustine Nitrosoureas: Carmustine Fotemustine
Asparaginase
Chemotherapy medication
Chlormethine Cyclophosphamide# (Ifosfamide# Trofosfamide) Chlorambucil# Melphalan (Melphalan flufenamide) Prednimustine Uramustine Nitrosoureas: Carmustine Fotemustine
Vinblastine
Abnormal number or structure of chromosomes
Notably, exposure to DNA-damaging agents, such as the chemotherapy drug Melphalan, can induce inter-strand DNA crosslinks that escape paternal repair, potentially
Chromosome_abnormality
Chemical compound
Chlormethine Cyclophosphamide# (Ifosfamide# Trofosfamide) Chlorambucil# Melphalan (Melphalan flufenamide) Prednimustine Uramustine Nitrosoureas: Carmustine Fotemustine
Camptothecin
Medical condition
medications and drugs include Chlorambucil, chloramphenicol, cyclophosphamide, melphalan, nitrogen mustards, phenylbutazone, and procarbazine. Genetic disorders
Subleukemic_leukemia
Chemical compound
Chlormethine Cyclophosphamide# (Ifosfamide# Trofosfamide) Chlorambucil# Melphalan (Melphalan flufenamide) Prednimustine Uramustine Nitrosoureas: Carmustine Fotemustine
Darinaparsin
Chemical compound
Chlormethine Cyclophosphamide# (Ifosfamide# Trofosfamide) Chlorambucil# Melphalan (Melphalan flufenamide) Prednimustine Uramustine Nitrosoureas: Carmustine Fotemustine
Capecitabine
Drug for treatment of breast cancer
Chlormethine Cyclophosphamide# (Ifosfamide# Trofosfamide) Chlorambucil# Melphalan (Melphalan flufenamide) Prednimustine Uramustine Nitrosoureas: Carmustine Fotemustine
Utidelone
Pharmaceutical drug
Chlormethine Cyclophosphamide# (Ifosfamide# Trofosfamide) Chlorambucil# Melphalan (Melphalan flufenamide) Prednimustine Uramustine Nitrosoureas: Carmustine Fotemustine
Tebentafusp
Diverse collection of blood-related cancers
treatments such as chemotherapy (especially alkylating agents such as melphalan, cyclophosphamide, busulfan, and chlorambucil) and radiotherapy can affect
Myelodysplastic_syndrome
Insertion of molecules between DNA
Chlormethine Cyclophosphamide# (Ifosfamide# Trofosfamide) Chlorambucil# Melphalan (Melphalan flufenamide) Prednimustine Uramustine Nitrosoureas: Carmustine Fotemustine
Intercalation_(biochemistry)
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