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Chemical compound
Ribociclib, sold under the brand name Kisqali, is a medication used for the treatment of certain kinds of breast cancer. Ribociclib is a kinase inhibitor
Ribociclib
Any chemical that inhibits the function of CDKs
FDA approved, but several compounds are in clinical trials. See also Ribociclib#Mechanism of action re: CDK4 The cell cycle is a highly regulated process
CDK_inhibitor
Medication for HR+ HER2– breast cancer
approved ribociclib, owned by Novartis, as a combination therapy with aromatase inhibitors for indications similar to those of palbociclib and ribociclib. Notably
Palbociclib
Chemical compound
inhibitors FI (Tipifarnib§) CDK inhibitors (Abemaciclib Alvocidib† Palbociclib Ribociclib Seliciclib†) PrI Bortezomib# Carfilzomib Oprozomib Ixazomib PhI (Anagrelide)
Vepdegestrant
Pharmaceutical drug
inhibitors FI (Tipifarnib§) CDK inhibitors (Abemaciclib Alvocidib† Palbociclib Ribociclib Seliciclib†) PrI Bortezomib# Carfilzomib Oprozomib Ixazomib PhI (Anagrelide)
Fuzuloparib
PARP inhibitor anti-cancer drug compound
inhibitors FI (Tipifarnib§) CDK inhibitors (Abemaciclib Alvocidib† Palbociclib Ribociclib Seliciclib†) PrI Bortezomib# Carfilzomib Oprozomib Ixazomib PhI (Anagrelide)
Pamiparib
Experimental cancer drug
inhibitors FI (Tipifarnib§) CDK inhibitors (Abemaciclib Alvocidib† Palbociclib Ribociclib Seliciclib†) PrI Bortezomib# Carfilzomib Oprozomib Ixazomib PhI (Anagrelide)
Divarasib
Chemical compound
inhibitors FI (Tipifarnib§) CDK inhibitors (Abemaciclib Alvocidib† Palbociclib Ribociclib Seliciclib†) PrI Bortezomib# Carfilzomib Oprozomib Ixazomib PhI (Anagrelide)
Dordaviprone
Cancer that originates in mammary glands
fulvestrant, often used in combination with CDK4/6 inhibitors (palbociclib, ribociclib, or abemaciclib). When one endocrine therapy fails, most will benefit
Breast_cancer
Drug Manufacturer Indication Letrozole/ribociclib Novartis Pharmaceuticals HR-positive, HER2-negative advanced or metastatic breast cancer Esketamine Janssen
List of drugs granted breakthrough therapy designation
List_of_drugs_granted_breakthrough_therapy_designation
Anti-breast cancer medication
shown in a study with rifampicin. Like the related drugs palbociclib and ribociclib, abemaciclib inhibits the enzymes cyclin-dependent kinase 4 (CDK4) and
Abemaciclib
Class of enzymes
metastatic breast cancer, often in combination with endocrine therapy. Ribociclib, demonstrating similar efficacy to palbociclib, is also approved for HR+/HER2-
Cyclin-dependent_kinase
Swiss multinational pharmaceutical corporation
Jakavi/Jakafi (ruxolitinib) Myelofibrosis (of intermediate to high risk) Kisqali (ribociclib) Breast Cancer 1,231 2022 Kymriah (tisagenlecleucel) Acute lymphoblastic
Novartis
Combination medication
inhibitors FI (Tipifarnib§) CDK inhibitors (Abemaciclib Alvocidib† Palbociclib Ribociclib Seliciclib†) PrI Bortezomib# Carfilzomib Oprozomib Ixazomib PhI (Anagrelide)
Niraparib/abiraterone_acetate
Chemical compound
inhibitors FI (Tipifarnib§) CDK inhibitors (Abemaciclib Alvocidib† Palbociclib Ribociclib Seliciclib†) PrI Bortezomib# Carfilzomib Oprozomib Ixazomib PhI (Anagrelide)
4-Hydroxycyclophosphamide
Nonsteroidal anti-inflammatory medication
inhibitors FI (Tipifarnib§) CDK inhibitors (Abemaciclib Alvocidib† Palbociclib Ribociclib Seliciclib†) PrI Bortezomib# Carfilzomib Oprozomib Ixazomib PhI (Anagrelide)
Celecoxib
Medication
inhibitors FI (Tipifarnib§) CDK inhibitors (Abemaciclib Alvocidib† Palbociclib Ribociclib Seliciclib†) PrI Bortezomib# Carfilzomib Oprozomib Ixazomib PhI (Anagrelide)
Tretinoin
Chemotherapy and immunosuppressant medication
inhibitors FI (Tipifarnib§) CDK inhibitors (Abemaciclib Alvocidib† Palbociclib Ribociclib Seliciclib†) PrI Bortezomib# Carfilzomib Oprozomib Ixazomib PhI (Anagrelide)
Methotrexate
Events leading to cell division
for anti-tumor effectiveness. Three Cdk4/6 inhibitors – palbociclib, ribociclib, and abemaciclib – currently received FDA approval for clinical use to
Cell_cycle
Chemical compound
inhibitors FI (Tipifarnib§) CDK inhibitors (Abemaciclib Alvocidib† Palbociclib Ribociclib Seliciclib†) PrI Bortezomib# Carfilzomib Oprozomib Ixazomib PhI (Anagrelide)
Phenanthriplatin
Cancer medication
inhibitors FI (Tipifarnib§) CDK inhibitors (Abemaciclib Alvocidib† Palbociclib Ribociclib Seliciclib†) PrI Bortezomib# Carfilzomib Oprozomib Ixazomib PhI (Anagrelide)
Irinotecan
Systematic naming of drugs
vandetanib -ciclib Cyclin-dependent kinase 4/CDK6 inhibitors palbociclib, ribociclib -degib hedgehog signaling pathway inhibitors vismodegib, sonidegib -denib
Drug_nomenclature
Pharmaceutical drug classification
L01EE05 Mirdametinib L01EE06 Tunlametinib L01EF01 Palbociclib L01EF02 Ribociclib L01EF03 Abemaciclib L01EG01 Temsirolimus L01EG02 Everolimus L01EG03 Ridaforolimus
ATC_code_L01
Chemical compound
versus fulvestrant, both combined with a CDK4/6 inhibitor (palbociclib, ribociclib, or abemaciclib), in patients with ER+, HER2-negative advanced breast
Giredestrant
Chemotherapy medication
inhibitors FI (Tipifarnib§) CDK inhibitors (Abemaciclib Alvocidib† Palbociclib Ribociclib Seliciclib†) PrI Bortezomib# Carfilzomib Oprozomib Ixazomib PhI (Anagrelide)
Ifosfamide
Regimen commonly used in chemotherapy
inhibitors FI (Tipifarnib§) CDK inhibitors (Abemaciclib Alvocidib† Palbociclib Ribociclib Seliciclib†) PrI Bortezomib# Carfilzomib Oprozomib Ixazomib PhI (Anagrelide)
Chemotherapy_regimen
Enzyme that metabolizes substances by oxidation
hypertension and chronic angina pectoris) nefazodone (antidepressant) ribociclib tucatinib chloramphenicol (antibiotic) some azole antifungals: ketoconazole
CYP3A4
Compounds that inhibit the activity of DNA topoisomerases
inhibitors FI (Tipifarnib§) CDK inhibitors (Abemaciclib Alvocidib† Palbociclib Ribociclib Seliciclib†) PrI Bortezomib# Carfilzomib Oprozomib Ixazomib PhI (Anagrelide)
Topoisomerase_inhibitor
Chemotherapy medication
inhibitors FI (Tipifarnib§) CDK inhibitors (Abemaciclib Alvocidib† Palbociclib Ribociclib Seliciclib†) PrI Bortezomib# Carfilzomib Oprozomib Ixazomib PhI (Anagrelide)
Doxorubicin
Cancer drug being studied
inhibitors FI (Tipifarnib§) CDK inhibitors (Abemaciclib Alvocidib† Palbociclib Ribociclib Seliciclib†) PrI Bortezomib# Carfilzomib Oprozomib Ixazomib PhI (Anagrelide)
Dibrospidium_chloride
Human protein
sparking interest in the development of small-molecule inhibitors of CDK4/6. Ribociclib are US FDA approved CDK4 and CDK6 inhibitors for the treatment of estrogen
Cyclin-dependent_kinase_4
Egyptian-American medical researcher
approved as cancer therapeutics, including palbociclib, abemaciclib and ribociclib. In 2017, El-Deiry's group discovered a micro-RNA family that inhibits
Wafik_El-Deiry
Medication used for cancer
inhibitors FI (Tipifarnib§) CDK inhibitors (Abemaciclib Alvocidib† Palbociclib Ribociclib Seliciclib†) PrI Bortezomib# Carfilzomib Oprozomib Ixazomib PhI (Anagrelide)
Paclitaxel
Industrial chemical and medication
inhibitors FI (Tipifarnib§) CDK inhibitors (Abemaciclib Alvocidib† Palbociclib Ribociclib Seliciclib†) PrI Bortezomib# Carfilzomib Oprozomib Ixazomib PhI (Anagrelide)
Arsenic_trioxide
Chemical compound
inhibitors FI (Tipifarnib§) CDK inhibitors (Abemaciclib Alvocidib† Palbociclib Ribociclib Seliciclib†) PrI Bortezomib# Carfilzomib Oprozomib Ixazomib PhI (Anagrelide)
Epacadostat
Chemotherapy medication
inhibitors FI (Tipifarnib§) CDK inhibitors (Abemaciclib Alvocidib† Palbociclib Ribociclib Seliciclib†) PrI Bortezomib# Carfilzomib Oprozomib Ixazomib PhI (Anagrelide)
Fluorouracil
Chemical compound
inhibitors FI (Tipifarnib§) CDK inhibitors (Abemaciclib Alvocidib† Palbociclib Ribociclib Seliciclib†) PrI Bortezomib# Carfilzomib Oprozomib Ixazomib PhI (Anagrelide)
Cabazitaxel
Medication used to treat cancer
inhibitors FI (Tipifarnib§) CDK inhibitors (Abemaciclib Alvocidib† Palbociclib Ribociclib Seliciclib†) PrI Bortezomib# Carfilzomib Oprozomib Ixazomib PhI (Anagrelide)
Carboplatin
Anti-cancer medication
inhibitors FI (Tipifarnib§) CDK inhibitors (Abemaciclib Alvocidib† Palbociclib Ribociclib Seliciclib†) PrI Bortezomib# Carfilzomib Oprozomib Ixazomib PhI (Anagrelide)
Vorasidenib
Family of chemical compounds
inhibitors FI (Tipifarnib§) CDK inhibitors (Abemaciclib Alvocidib† Palbociclib Ribociclib Seliciclib†) PrI Bortezomib# Carfilzomib Oprozomib Ixazomib PhI (Anagrelide)
Nitrogen_mustard
Chemical compound
inhibitors FI (Tipifarnib§) CDK inhibitors (Abemaciclib Alvocidib† Palbociclib Ribociclib Seliciclib†) PrI Bortezomib# Carfilzomib Oprozomib Ixazomib PhI (Anagrelide)
Elesclomol
Cancer medication
inhibitors FI (Tipifarnib§) CDK inhibitors (Abemaciclib Alvocidib† Palbociclib Ribociclib Seliciclib†) PrI Bortezomib# Carfilzomib Oprozomib Ixazomib PhI (Anagrelide)
Temozolomide
Multi-protein structure
inhibitors have been approved or are in late-stage development: palbociclib, ribociclib, and abemaciclib. All three of these inhibitors are ATP-competitive, orally
Cyclin_D/Cdk4
Cancer drug
inhibitors FI (Tipifarnib§) CDK inhibitors (Abemaciclib Alvocidib† Palbociclib Ribociclib Seliciclib†) PrI Bortezomib# Carfilzomib Oprozomib Ixazomib PhI (Anagrelide)
Protein-bound_paclitaxel
Chemical compound
inhibitors FI (Tipifarnib§) CDK inhibitors (Abemaciclib Alvocidib† Palbociclib Ribociclib Seliciclib†) PrI Bortezomib# Carfilzomib Oprozomib Ixazomib PhI (Anagrelide)
Capecitabine
Chemical compound
inhibitors FI (Tipifarnib§) CDK inhibitors (Abemaciclib Alvocidib† Palbociclib Ribociclib Seliciclib†) PrI Bortezomib# Carfilzomib Oprozomib Ixazomib PhI (Anagrelide)
Tiazofurin
Chemical compound
inhibitors FI (Tipifarnib§) CDK inhibitors (Abemaciclib Alvocidib† Palbociclib Ribociclib Seliciclib†) PrI Bortezomib# Carfilzomib Oprozomib Ixazomib PhI (Anagrelide)
Carboquone
Pharmaceutical drug
inhibitors FI (Tipifarnib§) CDK inhibitors (Abemaciclib Alvocidib† Palbociclib Ribociclib Seliciclib†) PrI Bortezomib# Carfilzomib Oprozomib Ixazomib PhI (Anagrelide)
Pegaspargase
Glycopeptide antibiotic used to treat various cancers
inhibitors FI (Tipifarnib§) CDK inhibitors (Abemaciclib Alvocidib† Palbociclib Ribociclib Seliciclib†) PrI Bortezomib# Carfilzomib Oprozomib Ixazomib PhI (Anagrelide)
Bleomycin
Pharmaceutical drug classification
inhibitors FI (Tipifarnib§) CDK inhibitors (Abemaciclib Alvocidib† Palbociclib Ribociclib Seliciclib†) PrI Bortezomib# Carfilzomib Oprozomib Ixazomib PhI (Anagrelide)
ATC_code_L
Chemical compound
inhibitors FI (Tipifarnib§) CDK inhibitors (Abemaciclib Alvocidib† Palbociclib Ribociclib Seliciclib†) PrI Bortezomib# Carfilzomib Oprozomib Ixazomib PhI (Anagrelide)
Mercaptopurine
Pharmaceutical drugs
inhibitors FI (Tipifarnib§) CDK inhibitors (Abemaciclib Alvocidib† Palbociclib Ribociclib Seliciclib†) PrI Bortezomib# Carfilzomib Oprozomib Ixazomib PhI (Anagrelide)
Alkylating antineoplastic agent
Alkylating_antineoplastic_agent
Chemical compound
inhibitors FI (Tipifarnib§) CDK inhibitors (Abemaciclib Alvocidib† Palbociclib Ribociclib Seliciclib†) PrI Bortezomib# Carfilzomib Oprozomib Ixazomib PhI (Anagrelide)
Azacitidine
Chemical compound and pharmaceutical drug
inhibitors FI (Tipifarnib§) CDK inhibitors (Abemaciclib Alvocidib† Palbociclib Ribociclib Seliciclib†) PrI Bortezomib# Carfilzomib Oprozomib Ixazomib PhI (Anagrelide)
Cisplatin
Tumor originating in adipose (fat) tissue
Research through Collaboration in collaboration with Eli Lilly and Company. Ribociclib, also a CDK4 and CDK6 gene inhibitor, in combination with a mTOR inhibitor
Liposarcoma
Chemical compound
inhibitors FI (Tipifarnib§) CDK inhibitors (Abemaciclib Alvocidib† Palbociclib Ribociclib Seliciclib†) PrI Bortezomib# Carfilzomib Oprozomib Ixazomib PhI (Anagrelide)
Talazoparib
Medication used as chemotherapy and to suppress the immune system
inhibitors FI (Tipifarnib§) CDK inhibitors (Abemaciclib Alvocidib† Palbociclib Ribociclib Seliciclib†) PrI Bortezomib# Carfilzomib Oprozomib Ixazomib PhI (Anagrelide)
Cyclophosphamide
Chemotherapy medication
inhibitors FI (Tipifarnib§) CDK inhibitors (Abemaciclib Alvocidib† Palbociclib Ribociclib Seliciclib†) PrI Bortezomib# Carfilzomib Oprozomib Ixazomib PhI (Anagrelide)
Vinblastine
Chemical compound
inhibitors FI (Tipifarnib§) CDK inhibitors (Abemaciclib Alvocidib† Palbociclib Ribociclib Seliciclib†) PrI Bortezomib# Carfilzomib Oprozomib Ixazomib PhI (Anagrelide)
Omacetaxine_mepesuccinate
Chemical compound
inhibitors FI (Tipifarnib§) CDK inhibitors (Abemaciclib Alvocidib† Palbociclib Ribociclib Seliciclib†) PrI Bortezomib# Carfilzomib Oprozomib Ixazomib PhI (Anagrelide)
Gemcitabine
Chemical compound (cancer therapy drug)
inhibitors FI (Tipifarnib§) CDK inhibitors (Abemaciclib Alvocidib† Palbociclib Ribociclib Seliciclib†) PrI Bortezomib# Carfilzomib Oprozomib Ixazomib PhI (Anagrelide)
Olaparib
Chemical compound; chemotherapy medication
inhibitors FI (Tipifarnib§) CDK inhibitors (Abemaciclib Alvocidib† Palbociclib Ribociclib Seliciclib†) PrI Bortezomib# Carfilzomib Oprozomib Ixazomib PhI (Anagrelide)
Vincristine
Combination drug
inhibitors FI (Tipifarnib§) CDK inhibitors (Abemaciclib Alvocidib† Palbociclib Ribociclib Seliciclib†) PrI Bortezomib# Carfilzomib Oprozomib Ixazomib PhI (Anagrelide)
Tegafur/gimeracil/oteracil
Gene therapy medication
inhibitors FI (Tipifarnib§) CDK inhibitors (Abemaciclib Alvocidib† Palbociclib Ribociclib Seliciclib†) PrI Bortezomib# Carfilzomib Oprozomib Ixazomib PhI (Anagrelide)
Lisocabtagene_maraleucel
Gene therapy medication used to treat multiple myeloma
inhibitors FI (Tipifarnib§) CDK inhibitors (Abemaciclib Alvocidib† Palbociclib Ribociclib Seliciclib†) PrI Bortezomib# Carfilzomib Oprozomib Ixazomib PhI (Anagrelide)
Ciltacabtagene_autoleucel
Medical condition
and CDK6). Other experimental CDK4/6 inhibitors include abemaciclib and ribociclib. Cancer stem cells (or cancer-initiating cells) are thought to be a small
Epithelioid_sarcoma
Chemical compound
inhibitors FI (Tipifarnib§) CDK inhibitors (Abemaciclib Alvocidib† Palbociclib Ribociclib Seliciclib†) PrI Bortezomib# Carfilzomib Oprozomib Ixazomib PhI (Anagrelide)
Navitoclax
Gene therapy medication
inhibitors FI (Tipifarnib§) CDK inhibitors (Abemaciclib Alvocidib† Palbociclib Ribociclib Seliciclib†) PrI Bortezomib# Carfilzomib Oprozomib Ixazomib PhI (Anagrelide)
Idecabtagene_vicleucel
Medication
inhibitors FI (Tipifarnib§) CDK inhibitors (Abemaciclib Alvocidib† Palbociclib Ribociclib Seliciclib†) PrI Bortezomib# Carfilzomib Oprozomib Ixazomib PhI (Anagrelide)
Vusolimogene_oderparepvec
Chemicals that inhibit the use of a metabolite
inhibitors FI (Tipifarnib§) CDK inhibitors (Abemaciclib Alvocidib† Palbociclib Ribociclib Seliciclib†) PrI Bortezomib# Carfilzomib Oprozomib Ixazomib PhI (Anagrelide)
Pyrimidine_analogue
Medication
inhibitors FI (Tipifarnib§) CDK inhibitors (Abemaciclib Alvocidib† Palbociclib Ribociclib Seliciclib†) PrI Bortezomib# Carfilzomib Oprozomib Ixazomib PhI (Anagrelide)
Venetoclax
Pharmaceutical drug
inhibitors FI (Tipifarnib§) CDK inhibitors (Abemaciclib Alvocidib† Palbociclib Ribociclib Seliciclib†) PrI Bortezomib# Carfilzomib Oprozomib Ixazomib PhI (Anagrelide)
Oxaliplatin
Pharmaceutical drug
inhibitors FI (Tipifarnib§) CDK inhibitors (Abemaciclib Alvocidib† Palbociclib Ribociclib Seliciclib†) PrI Bortezomib# Carfilzomib Oprozomib Ixazomib PhI (Anagrelide)
Tebentafusp
Class of drugs used to treat malignant tumors
inhibitors FI (Tipifarnib§) CDK inhibitors (Abemaciclib Alvocidib† Palbociclib Ribociclib Seliciclib†) PrI Bortezomib# Carfilzomib Oprozomib Ixazomib PhI (Anagrelide)
Antineoplastic
Chemotherapy medication
inhibitors FI (Tipifarnib§) CDK inhibitors (Abemaciclib Alvocidib† Palbociclib Ribociclib Seliciclib†) PrI Bortezomib# Carfilzomib Oprozomib Ixazomib PhI (Anagrelide)
Daunorubicin
Mammalian protein found in humans
small molecule CDK4/6 inhibitors (palbociclib (Ibrance, Pfizer 2015), ribociclib (Kisqali, Novartis 2017), and abemaciclib (Verzenio, Eli Lilly 2017) for
Retinoblastoma_protein
Medication
inhibitors FI (Tipifarnib§) CDK inhibitors (Abemaciclib Alvocidib† Palbociclib Ribociclib Seliciclib†) PrI Bortezomib# Carfilzomib Oprozomib Ixazomib PhI (Anagrelide)
Lifileucel
Chemical compound
inhibitors FI (Tipifarnib§) CDK inhibitors (Abemaciclib Alvocidib† Palbociclib Ribociclib Seliciclib†) PrI Bortezomib# Carfilzomib Oprozomib Ixazomib PhI (Anagrelide)
Mubritinib
Drugs that are useful against cancer
inhibitors FI (Tipifarnib§) CDK inhibitors (Abemaciclib Alvocidib† Palbociclib Ribociclib Seliciclib†) PrI Bortezomib# Carfilzomib Oprozomib Ixazomib PhI (Anagrelide)
List of chemotherapeutic agents
List_of_chemotherapeutic_agents
Chemical compound
inhibitors FI (Tipifarnib§) CDK inhibitors (Abemaciclib Alvocidib† Palbociclib Ribociclib Seliciclib†) PrI Bortezomib# Carfilzomib Oprozomib Ixazomib PhI (Anagrelide)
Bortezomib
Chemotherapeutic agents used to treat cancer
inhibitors FI (Tipifarnib§) CDK inhibitors (Abemaciclib Alvocidib† Palbociclib Ribociclib Seliciclib†) PrI Bortezomib# Carfilzomib Oprozomib Ixazomib PhI (Anagrelide)
Platinum-based_antineoplastic
Chemical compound
inhibitors FI (Tipifarnib§) CDK inhibitors (Abemaciclib Alvocidib† Palbociclib Ribociclib Seliciclib†) PrI Bortezomib# Carfilzomib Oprozomib Ixazomib PhI (Anagrelide)
Darinaparsin
Drug for treatment of breast cancer
inhibitors FI (Tipifarnib§) CDK inhibitors (Abemaciclib Alvocidib† Palbociclib Ribociclib Seliciclib†) PrI Bortezomib# Carfilzomib Oprozomib Ixazomib PhI (Anagrelide)
Utidelone
Investigational oral small-molecule drug
inhibitors FI (Tipifarnib§) CDK inhibitors (Abemaciclib Alvocidib† Palbociclib Ribociclib Seliciclib†) PrI Bortezomib# Carfilzomib Oprozomib Ixazomib PhI (Anagrelide)
Pelabresib
UK pharmaceutical company
biopharma partners into clinical trials and onto the market, including ribociclib (brand name “Kisqali”), a CDK4/CDK6 inhibitor discovered in collaboration
Astex_Pharmaceuticals
Chemotherapy regimen for colorectal cancer treatment
inhibitors FI (Tipifarnib§) CDK inhibitors (Abemaciclib Alvocidib† Palbociclib Ribociclib Seliciclib†) PrI Bortezomib# Carfilzomib Oprozomib Ixazomib PhI (Anagrelide)
FOLFIRI
Form of phototherapy
inhibitors FI (Tipifarnib§) CDK inhibitors (Abemaciclib Alvocidib† Palbociclib Ribociclib Seliciclib†) PrI Bortezomib# Carfilzomib Oprozomib Ixazomib PhI (Anagrelide)
Photodynamic_therapy
Chemotherapy medication
inhibitors FI (Tipifarnib§) CDK inhibitors (Abemaciclib Alvocidib† Palbociclib Ribociclib Seliciclib†) PrI Bortezomib# Carfilzomib Oprozomib Ixazomib PhI (Anagrelide)
Etoposide
Chemical compound
inhibitors FI (Tipifarnib§) CDK inhibitors (Abemaciclib Alvocidib† Palbociclib Ribociclib Seliciclib†) PrI Bortezomib# Carfilzomib Oprozomib Ixazomib PhI (Anagrelide)
Lurbinectedin
Chemical compound (chemotherapy medication)
inhibitors FI (Tipifarnib§) CDK inhibitors (Abemaciclib Alvocidib† Palbociclib Ribociclib Seliciclib†) PrI Bortezomib# Carfilzomib Oprozomib Ixazomib PhI (Anagrelide)
Cytarabine
Chemical compound
inhibitors FI (Tipifarnib§) CDK inhibitors (Abemaciclib Alvocidib† Palbociclib Ribociclib Seliciclib†) PrI Bortezomib# Carfilzomib Oprozomib Ixazomib PhI (Anagrelide)
Bendamustine
Enzymes that block actions of protein kinases
inhibitors FI (Tipifarnib§) CDK inhibitors (Abemaciclib Alvocidib† Palbociclib Ribociclib Seliciclib†) PrI Bortezomib# Carfilzomib Oprozomib Ixazomib PhI (Anagrelide)
Protein_kinase_inhibitor
Chemical compound
inhibitors FI (Tipifarnib§) CDK inhibitors (Abemaciclib Alvocidib† Palbociclib Ribociclib Seliciclib†) PrI Bortezomib# Carfilzomib Oprozomib Ixazomib PhI (Anagrelide)
Bexarotene
Gene therapy medication
inhibitors FI (Tipifarnib§) CDK inhibitors (Abemaciclib Alvocidib† Palbociclib Ribociclib Seliciclib†) PrI Bortezomib# Carfilzomib Oprozomib Ixazomib PhI (Anagrelide)
Nadofaragene_firadenovec
Chemical compound
inhibitors FI (Tipifarnib§) CDK inhibitors (Abemaciclib Alvocidib† Palbociclib Ribociclib Seliciclib†) PrI Bortezomib# Carfilzomib Oprozomib Ixazomib PhI (Anagrelide)
Carfilzomib
Pharmaceutical medication
inhibitors FI (Tipifarnib§) CDK inhibitors (Abemaciclib Alvocidib† Palbociclib Ribociclib Seliciclib†) PrI Bortezomib# Carfilzomib Oprozomib Ixazomib PhI (Anagrelide)
Calaspargase_pegol
Chemical compound
inhibitors FI (Tipifarnib§) CDK inhibitors (Abemaciclib Alvocidib† Palbociclib Ribociclib Seliciclib†) PrI Bortezomib# Carfilzomib Oprozomib Ixazomib PhI (Anagrelide)
Melphalan
Chemical compound
inhibitors FI (Tipifarnib§) CDK inhibitors (Abemaciclib Alvocidib† Palbociclib Ribociclib Seliciclib†) PrI Bortezomib# Carfilzomib Oprozomib Ixazomib PhI (Anagrelide)
Belzutifan
Chemical compound
inhibitors FI (Tipifarnib§) CDK inhibitors (Abemaciclib Alvocidib† Palbociclib Ribociclib Seliciclib†) PrI Bortezomib# Carfilzomib Oprozomib Ixazomib PhI (Anagrelide)
Lomustine
Chemical compound
inhibitors FI (Tipifarnib§) CDK inhibitors (Abemaciclib Alvocidib† Palbociclib Ribociclib Seliciclib†) PrI Bortezomib# Carfilzomib Oprozomib Ixazomib PhI (Anagrelide)
Mitomycin_C
RIBOCICLIB
RIBOCICLIB
RIBOCICLIB
RIBOCICLIB
RIBOCICLIB
RIBOCICLIB
RIBOCICLIB
RIBOCICLIB
RIBOCICLIB