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CENEGERMIN

  • Cenegermin

    • Pharmaceutical drug

    Cenegermin, sold under the brand name Oxervate, also known as recombinant human nerve growth factor, is a recombinant form of human nerve growth factor

    Cenegermin

    Cenegermin

  • Dompé Farmaceutici

    • Italian pharmaceutical company

    Anabasis product Cenegermin, an eye drop containing recombinant human nerve growth factor, as a treatment for neurotrophic keratitis. Cenegermin received fast

    Dompé Farmaceutici

    Dompé Farmaceutici

    Dompé_Farmaceutici

  • Braegen-02

    • Pharmaceutical compound

    (GPE, (1-3)IGF-1) Trofinetide LNGF (p75NTR) Agonists: BDNF BNN-20 BNN-27 Cenegermin DHEA DHEA-S NGF NT-3 NT-4 Antagonists: ALE-0540 Dexamethasone EVT-901

    Braegen-02

    Braegen-02

    Braegen-02

  • Fosgonimeton

    • Chemical compound

    (GPE, (1-3)IGF-1) Trofinetide LNGF (p75NTR) Agonists: BDNF BNN-20 BNN-27 Cenegermin DHEA DHEA-S NGF NT-3 NT-4 Antagonists: ALE-0540 Dexamethasone EVT-901

    Fosgonimeton

    Fosgonimeton

    Fosgonimeton

  • Nerve growth factor

    • Mammalian protein found in humans

    receptor kinase A. Recombinant human nerve growth factor (rhNGF; named cenegermin) has been formulated as an eye drop (0.002%), receiving approval by the

    Nerve growth factor

    Nerve growth factor

    Nerve_growth_factor

  • Sentinel

    • Topics referred to by the same term

    High Standard Manufacturing Company Sentinel, a brand name for the drug cenegermin Sentinel Offender Services, a for-profit probation company Sentinel Sound

    Sentinel

    Sentinel

  • Amivantamab

    • Monoclonal antibody

    (GPE, (1-3)IGF-1) Trofinetide LNGF (p75NTR) Agonists: BDNF BNN-20 BNN-27 Cenegermin DHEA DHEA-S NGF NT-3 NT-4 Antagonists: ALE-0540 Dexamethasone EVT-901

    Amivantamab

    Amivantamab

    Amivantamab

  • Nilotinib

    • Chemical compound

    (GPE, (1-3)IGF-1) Trofinetide LNGF (p75NTR) Agonists: BDNF BNN-20 BNN-27 Cenegermin DHEA DHEA-S NGF NT-3 NT-4 Antagonists: ALE-0540 Dexamethasone EVT-901

    Nilotinib

    Nilotinib

    Nilotinib

  • CCN family member 2

    • Protein found in humans

    (GPE, (1-3)IGF-1) Trofinetide LNGF (p75NTR) Agonists: BDNF BNN-20 BNN-27 Cenegermin DHEA DHEA-S NGF NT-3 NT-4 Antagonists: ALE-0540 Dexamethasone EVT-901

    CCN family member 2

    CCN family member 2

    CCN_family_member_2

  • Amitriptyline

    • Tricyclic antidepressant

    (GPE, (1-3)IGF-1) Trofinetide LNGF (p75NTR) Agonists: BDNF BNN-20 BNN-27 Cenegermin DHEA DHEA-S NGF NT-3 NT-4 Antagonists: ALE-0540 Dexamethasone EVT-901

    Amitriptyline

    Amitriptyline

    Amitriptyline

  • Asciminib

    • Chemical compound

    (GPE, (1-3)IGF-1) Trofinetide LNGF (p75NTR) Agonists: BDNF BNN-20 BNN-27 Cenegermin DHEA DHEA-S NGF NT-3 NT-4 Antagonists: ALE-0540 Dexamethasone EVT-901

    Asciminib

    Asciminib

    Asciminib

  • Testosterone

    • Primary male sex hormone

    (GPE, (1-3)IGF-1) Trofinetide LNGF (p75NTR) Agonists: BDNF BNN-20 BNN-27 Cenegermin DHEA DHEA-S NGF NT-3 NT-4 Antagonists: ALE-0540 Dexamethasone EVT-901

    Testosterone

    Testosterone

    Testosterone

  • Selpercatinib

    • Chemical compound

    (GPE, (1-3)IGF-1) Trofinetide LNGF (p75NTR) Agonists: BDNF BNN-20 BNN-27 Cenegermin DHEA DHEA-S NGF NT-3 NT-4 Antagonists: ALE-0540 Dexamethasone EVT-901

    Selpercatinib

    Selpercatinib

    Selpercatinib

  • ACD856

    • TrkA and TrkB positive modulator

    (GPE, (1-3)IGF-1) Trofinetide LNGF (p75NTR) Agonists: BDNF BNN-20 BNN-27 Cenegermin DHEA DHEA-S NGF NT-3 NT-4 Antagonists: ALE-0540 Dexamethasone EVT-901

    ACD856

    ACD856

  • Neurotrophic factor receptor

    • Group of protein families

    (GPE, (1-3)IGF-1) Trofinetide LNGF (p75NTR) Agonists: BDNF BNN-20 BNN-27 Cenegermin DHEA DHEA-S NGF NT-3 NT-4 Antagonists: ALE-0540 Dexamethasone EVT-901

    Neurotrophic factor receptor

    Neurotrophic_factor_receptor

  • Erythropoietin

    • Protein that stimulates red blood cell production

    (GPE, (1-3)IGF-1) Trofinetide LNGF (p75NTR) Agonists: BDNF BNN-20 BNN-27 Cenegermin DHEA DHEA-S NGF NT-3 NT-4 Antagonists: ALE-0540 Dexamethasone EVT-901

    Erythropoietin

    Erythropoietin

    Erythropoietin

  • ATC code S01

    • Pharmaceutical drug classification

    preparations S01XA21 Mercaptamine S01XA22 Ocriplasmin S01XA23 Sirolimus S01XA24 Cenegermin S01XA25 Lifitegrast S01XA26 Riboflavin S01XA27 Voretigene neparvovec S01XA28

    ATC code S01

    ATC_code_S01

  • EPHA6

    • Protein-coding gene in the species Homo sapiens

    (GPE, (1-3)IGF-1) Trofinetide LNGF (p75NTR) Agonists: BDNF BNN-20 BNN-27 Cenegermin DHEA DHEA-S NGF NT-3 NT-4 Antagonists: ALE-0540 Dexamethasone EVT-901

    EPHA6

    EPHA6

    EPHA6

  • Dehydroepiandrosterone sulfate

    • Chemical compound

    (GPE, (1-3)IGF-1) Trofinetide LNGF (p75NTR) Agonists: BDNF BNN-20 BNN-27 Cenegermin DHEA DHEA-S NGF NT-3 NT-4 Antagonists: ALE-0540 Dexamethasone EVT-901

    Dehydroepiandrosterone sulfate

    Dehydroepiandrosterone sulfate

    Dehydroepiandrosterone_sulfate

  • Repotrectinib

    • Medication

    (GPE, (1-3)IGF-1) Trofinetide LNGF (p75NTR) Agonists: BDNF BNN-20 BNN-27 Cenegermin DHEA DHEA-S NGF NT-3 NT-4 Antagonists: ALE-0540 Dexamethasone EVT-901

    Repotrectinib

    Repotrectinib

    Repotrectinib

  • BNN-20

    • Chemical compound

    (GPE, (1-3)IGF-1) Trofinetide LNGF (p75NTR) Agonists: BDNF BNN-20 BNN-27 Cenegermin DHEA DHEA-S NGF NT-3 NT-4 Antagonists: ALE-0540 Dexamethasone EVT-901

    BNN-20

    BNN-20

    BNN-20

  • Dexamethasone

    • Corticosteroid medication

    (GPE, (1-3)IGF-1) Trofinetide LNGF (p75NTR) Agonists: BDNF BNN-20 BNN-27 Cenegermin DHEA DHEA-S NGF NT-3 NT-4 Antagonists: ALE-0540 Dexamethasone EVT-901

    Dexamethasone

    Dexamethasone

    Dexamethasone

  • Lipegfilgrastim

    • Pharmaceutical drug

    (GPE, (1-3)IGF-1) Trofinetide LNGF (p75NTR) Agonists: BDNF BNN-20 BNN-27 Cenegermin DHEA DHEA-S NGF NT-3 NT-4 Antagonists: ALE-0540 Dexamethasone EVT-901

    Lipegfilgrastim

    Lipegfilgrastim

  • Bevacizumab

    • Medication

    (GPE, (1-3)IGF-1) Trofinetide LNGF (p75NTR) Agonists: BDNF BNN-20 BNN-27 Cenegermin DHEA DHEA-S NGF NT-3 NT-4 Antagonists: ALE-0540 Dexamethasone EVT-901

    Bevacizumab

    Bevacizumab

  • Growth factor

    • Protein or other substance that stimulates cellular proliferation

    (GPE, (1-3)IGF-1) Trofinetide LNGF (p75NTR) Agonists: BDNF BNN-20 BNN-27 Cenegermin DHEA DHEA-S NGF NT-3 NT-4 Antagonists: ALE-0540 Dexamethasone EVT-901

    Growth factor

    Growth_factor

  • Insulin-like growth factor 1

    • Protein found in humans

    (GPE, (1-3)IGF-1) Trofinetide LNGF (p75NTR) Agonists: BDNF BNN-20 BNN-27 Cenegermin DHEA DHEA-S NGF NT-3 NT-4 Antagonists: ALE-0540 Dexamethasone EVT-901

    Insulin-like growth factor 1

    Insulin-like growth factor 1

    Insulin-like_growth_factor_1

  • FGF4

    • Fibroblast growth factor gene

    (GPE, (1-3)IGF-1) Trofinetide LNGF (p75NTR) Agonists: BDNF BNN-20 BNN-27 Cenegermin DHEA DHEA-S NGF NT-3 NT-4 Antagonists: ALE-0540 Dexamethasone EVT-901

    FGF4

    FGF4

    FGF4

  • Becaplermin

    • Pharmaceutical drug

    (GPE, (1-3)IGF-1) Trofinetide LNGF (p75NTR) Agonists: BDNF BNN-20 BNN-27 Cenegermin DHEA DHEA-S NGF NT-3 NT-4 Antagonists: ALE-0540 Dexamethasone EVT-901

    Becaplermin

    Becaplermin

  • Vascular endothelial growth factor

    • Protein involved in blood vessel growth

    (GPE, (1-3)IGF-1) Trofinetide LNGF (p75NTR) Agonists: BDNF BNN-20 BNN-27 Cenegermin DHEA DHEA-S NGF NT-3 NT-4 Antagonists: ALE-0540 Dexamethasone EVT-901

    Vascular endothelial growth factor

    Vascular_endothelial_growth_factor

  • Icrucumab

    • Monoclonal antibody

    (GPE, (1-3)IGF-1) Trofinetide LNGF (p75NTR) Agonists: BDNF BNN-20 BNN-27 Cenegermin DHEA DHEA-S NGF NT-3 NT-4 Antagonists: ALE-0540 Dexamethasone EVT-901

    Icrucumab

    Icrucumab

  • Anti-VEGF

    • Medication which blocks growth of blood vessels

    (GPE, (1-3)IGF-1) Trofinetide LNGF (p75NTR) Agonists: BDNF BNN-20 BNN-27 Cenegermin DHEA DHEA-S NGF NT-3 NT-4 Antagonists: ALE-0540 Dexamethasone EVT-901

    Anti-VEGF

    Anti-VEGF

    Anti-VEGF

  • Cediranib

    • Chemical compound

    (GPE, (1-3)IGF-1) Trofinetide LNGF (p75NTR) Agonists: BDNF BNN-20 BNN-27 Cenegermin DHEA DHEA-S NGF NT-3 NT-4 Antagonists: ALE-0540 Dexamethasone EVT-901

    Cediranib

    Cediranib

    Cediranib

  • Keratinocyte growth factor

    • InterPro family

    (GPE, (1-3)IGF-1) Trofinetide LNGF (p75NTR) Agonists: BDNF BNN-20 BNN-27 Cenegermin DHEA DHEA-S NGF NT-3 NT-4 Antagonists: ALE-0540 Dexamethasone EVT-901

    Keratinocyte growth factor

    Keratinocyte_growth_factor

  • FGF17

    • Protein-coding gene in the species Homo sapiens

    (GPE, (1-3)IGF-1) Trofinetide LNGF (p75NTR) Agonists: BDNF BNN-20 BNN-27 Cenegermin DHEA DHEA-S NGF NT-3 NT-4 Antagonists: ALE-0540 Dexamethasone EVT-901

    FGF17

    FGF17

    FGF17

  • Wnt signaling pathway

    • Group of signal transduction pathways involved in embryonic development

    (GPE, (1-3)IGF-1) Trofinetide LNGF (p75NTR) Agonists: BDNF BNN-20 BNN-27 Cenegermin DHEA DHEA-S NGF NT-3 NT-4 Antagonists: ALE-0540 Dexamethasone EVT-901

    Wnt signaling pathway

    Wnt_signaling_pathway

  • Dihexa

    • Chemical compound

    (GPE, (1-3)IGF-1) Trofinetide LNGF (p75NTR) Agonists: BDNF BNN-20 BNN-27 Cenegermin DHEA DHEA-S NGF NT-3 NT-4 Antagonists: ALE-0540 Dexamethasone EVT-901

    Dihexa

    Dihexa

    Dihexa

  • Insulin

    • Peptide hormone

    (GPE, (1-3)IGF-1) Trofinetide LNGF (p75NTR) Agonists: BDNF BNN-20 BNN-27 Cenegermin DHEA DHEA-S NGF NT-3 NT-4 Antagonists: ALE-0540 Dexamethasone EVT-901

    Insulin

    Insulin

    Insulin

  • Tyrosine kinase inhibitor

    • Drug typically used in cancer treatment

    (GPE, (1-3)IGF-1) Trofinetide LNGF (p75NTR) Agonists: BDNF BNN-20 BNN-27 Cenegermin DHEA DHEA-S NGF NT-3 NT-4 Antagonists: ALE-0540 Dexamethasone EVT-901

    Tyrosine kinase inhibitor

    Tyrosine kinase inhibitor

    Tyrosine_kinase_inhibitor

  • Cerebrolysin

    • Experimental drug for neurodegenerative disorders

    (GPE, (1-3)IGF-1) Trofinetide LNGF (p75NTR) Agonists: BDNF BNN-20 BNN-27 Cenegermin DHEA DHEA-S NGF NT-3 NT-4 Antagonists: ALE-0540 Dexamethasone EVT-901

    Cerebrolysin

    Cerebrolysin

  • Neurotrophic keratitis

    • Medical condition

    in NK patients. A recombinant human NGF (rhNGF) eye drop formulation, cenegermin, has been developed for clinical use and has recently been approved in

    Neurotrophic keratitis

    Neurotrophic_keratitis

  • Imatinib

    • Chemical compound

    (GPE, (1-3)IGF-1) Trofinetide LNGF (p75NTR) Agonists: BDNF BNN-20 BNN-27 Cenegermin DHEA DHEA-S NGF NT-3 NT-4 Antagonists: ALE-0540 Dexamethasone EVT-901

    Imatinib

    Imatinib

    Imatinib

  • HER2

    • Mammalian protein found in humans

    (GPE, (1-3)IGF-1) Trofinetide LNGF (p75NTR) Agonists: BDNF BNN-20 BNN-27 Cenegermin DHEA DHEA-S NGF NT-3 NT-4 Antagonists: ALE-0540 Dexamethasone EVT-901

    HER2

    HER2

    HER2

  • Filgrastim

    • Medication

    (GPE, (1-3)IGF-1) Trofinetide LNGF (p75NTR) Agonists: BDNF BNN-20 BNN-27 Cenegermin DHEA DHEA-S NGF NT-3 NT-4 Antagonists: ALE-0540 Dexamethasone EVT-901

    Filgrastim

    Filgrastim

    Filgrastim

  • Fibroblast growth factor receptor 3

    • Gene involved in the most common form of dwarfism

    (GPE, (1-3)IGF-1) Trofinetide LNGF (p75NTR) Agonists: BDNF BNN-20 BNN-27 Cenegermin DHEA DHEA-S NGF NT-3 NT-4 Antagonists: ALE-0540 Dexamethasone EVT-901

    Fibroblast growth factor receptor 3

    Fibroblast growth factor receptor 3

    Fibroblast_growth_factor_receptor_3

  • Tavilermide

    • Chemical compound

    I clinical trials for the treatment of glaucoma; studies are ongoing. Cenegermin Meerovitch K, Torkildsen G, Lonsdale J, Goldfarb H, Lama T, Cumberlidge

    Tavilermide

    Tavilermide

    Tavilermide

  • Brain-derived neurotrophic factor

    • Protein found in humans

    (GPE, (1-3)IGF-1) Trofinetide LNGF (p75NTR) Agonists: BDNF BNN-20 BNN-27 Cenegermin DHEA DHEA-S NGF NT-3 NT-4 Antagonists: ALE-0540 Dexamethasone EVT-901

    Brain-derived neurotrophic factor

    Brain-derived neurotrophic factor

    Brain-derived_neurotrophic_factor

  • IGF-1 LR3

    • Synthetic protein

    (GPE, (1-3)IGF-1) Trofinetide LNGF (p75NTR) Agonists: BDNF BNN-20 BNN-27 Cenegermin DHEA DHEA-S NGF NT-3 NT-4 Antagonists: ALE-0540 Dexamethasone EVT-901

    IGF-1 LR3

    IGF-1_LR3

  • Receptor tyrosine kinase

    • Class of enzymes

    (GPE, (1-3)IGF-1) Trofinetide LNGF (p75NTR) Agonists: BDNF BNN-20 BNN-27 Cenegermin DHEA DHEA-S NGF NT-3 NT-4 Antagonists: ALE-0540 Dexamethasone EVT-901

    Receptor tyrosine kinase

    Receptor tyrosine kinase

    Receptor_tyrosine_kinase

  • Integrin

    • Transmembrane receptors involved in cellular adhesion and signalling

    (GPE, (1-3)IGF-1) Trofinetide LNGF (p75NTR) Agonists: BDNF BNN-20 BNN-27 Cenegermin DHEA DHEA-S NGF NT-3 NT-4 Antagonists: ALE-0540 Dexamethasone EVT-901

    Integrin

    Integrin

    Integrin

  • Insulin-like growth factor

    • Proteins similar to insulin that stimulate cell proliferation

    (GPE, (1-3)IGF-1) Trofinetide LNGF (p75NTR) Agonists: BDNF BNN-20 BNN-27 Cenegermin DHEA DHEA-S NGF NT-3 NT-4 Antagonists: ALE-0540 Dexamethasone EVT-901

    Insulin-like growth factor

    Insulin-like growth factor

    Insulin-like_growth_factor

  • Osimertinib

    • Chemical compound, used as a medication to treat lung cancer

    (GPE, (1-3)IGF-1) Trofinetide LNGF (p75NTR) Agonists: BDNF BNN-20 BNN-27 Cenegermin DHEA DHEA-S NGF NT-3 NT-4 Antagonists: ALE-0540 Dexamethasone EVT-901

    Osimertinib

    Osimertinib

    Osimertinib

  • Fibroblast growth factor 21

    • Protein-coding gene in mammals

    (GPE, (1-3)IGF-1) Trofinetide LNGF (p75NTR) Agonists: BDNF BNN-20 BNN-27 Cenegermin DHEA DHEA-S NGF NT-3 NT-4 Antagonists: ALE-0540 Dexamethasone EVT-901

    Fibroblast growth factor 21

    Fibroblast growth factor 21

    Fibroblast_growth_factor_21

  • Cetuximab

    • Pharmaceutical drug

    (GPE, (1-3)IGF-1) Trofinetide LNGF (p75NTR) Agonists: BDNF BNN-20 BNN-27 Cenegermin DHEA DHEA-S NGF NT-3 NT-4 Antagonists: ALE-0540 Dexamethasone EVT-901

    Cetuximab

    Cetuximab

    Cetuximab

  • KIT gene

    • Mammalian protein and protein-coding gene

    (GPE, (1-3)IGF-1) Trofinetide LNGF (p75NTR) Agonists: BDNF BNN-20 BNN-27 Cenegermin DHEA DHEA-S NGF NT-3 NT-4 Antagonists: ALE-0540 Dexamethasone EVT-901

    KIT gene

    KIT gene

    KIT_gene

  • Trastuzumab deruxtecan

    • Medication

    (GPE, (1-3)IGF-1) Trofinetide LNGF (p75NTR) Agonists: BDNF BNN-20 BNN-27 Cenegermin DHEA DHEA-S NGF NT-3 NT-4 Antagonists: ALE-0540 Dexamethasone EVT-901

    Trastuzumab deruxtecan

    Trastuzumab deruxtecan

    Trastuzumab_deruxtecan

  • Tesevatinib

    • Chemical compound

    (GPE, (1-3)IGF-1) Trofinetide LNGF (p75NTR) Agonists: BDNF BNN-20 BNN-27 Cenegermin DHEA DHEA-S NGF NT-3 NT-4 Antagonists: ALE-0540 Dexamethasone EVT-901

    Tesevatinib

    Tesevatinib

    Tesevatinib

  • Neurotrophic factors

    • Family of biomolecules

    (GPE, (1-3)IGF-1) Trofinetide LNGF (p75NTR) Agonists: BDNF BNN-20 BNN-27 Cenegermin DHEA DHEA-S NGF NT-3 NT-4 Antagonists: ALE-0540 Dexamethasone EVT-901

    Neurotrophic factors

    Neurotrophic_factors

  • Trastuzumab

    • Medication

    (GPE, (1-3)IGF-1) Trofinetide LNGF (p75NTR) Agonists: BDNF BNN-20 BNN-27 Cenegermin DHEA DHEA-S NGF NT-3 NT-4 Antagonists: ALE-0540 Dexamethasone EVT-901

    Trastuzumab

    Trastuzumab

    Trastuzumab

  • Epidermal growth factor

    • Protein that stimulates cell division and differentiation

    (GPE, (1-3)IGF-1) Trofinetide LNGF (p75NTR) Agonists: BDNF BNN-20 BNN-27 Cenegermin DHEA DHEA-S NGF NT-3 NT-4 Antagonists: ALE-0540 Dexamethasone EVT-901

    Epidermal growth factor

    Epidermal growth factor

    Epidermal_growth_factor

  • Fruquintinib

    • Medication

    (GPE, (1-3)IGF-1) Trofinetide LNGF (p75NTR) Agonists: BDNF BNN-20 BNN-27 Cenegermin DHEA DHEA-S NGF NT-3 NT-4 Antagonists: ALE-0540 Dexamethasone EVT-901

    Fruquintinib

    Fruquintinib

    Fruquintinib

  • Insulin-like growth factor 1 receptor

    • Cell receptor protein found in humans

    (GPE, (1-3)IGF-1) Trofinetide LNGF (p75NTR) Agonists: BDNF BNN-20 BNN-27 Cenegermin DHEA DHEA-S NGF NT-3 NT-4 Antagonists: ALE-0540 Dexamethasone EVT-901

    Insulin-like growth factor 1 receptor

    Insulin-like growth factor 1 receptor

    Insulin-like_growth_factor_1_receptor

  • Dasatinib

    • Chemical compound

    (GPE, (1-3)IGF-1) Trofinetide LNGF (p75NTR) Agonists: BDNF BNN-20 BNN-27 Cenegermin DHEA DHEA-S NGF NT-3 NT-4 Antagonists: ALE-0540 Dexamethasone EVT-901

    Dasatinib

    Dasatinib

    Dasatinib

  • Pertuzumab/trastuzumab/hyaluronidase

    • Combination drug

    (GPE, (1-3)IGF-1) Trofinetide LNGF (p75NTR) Agonists: BDNF BNN-20 BNN-27 Cenegermin DHEA DHEA-S NGF NT-3 NT-4 Antagonists: ALE-0540 Dexamethasone EVT-901

    Pertuzumab/trastuzumab/hyaluronidase

    Pertuzumab/trastuzumab/hyaluronidase

  • Encorafenib

    • Chemical compound

    (GPE, (1-3)IGF-1) Trofinetide LNGF (p75NTR) Agonists: BDNF BNN-20 BNN-27 Cenegermin DHEA DHEA-S NGF NT-3 NT-4 Antagonists: ALE-0540 Dexamethasone EVT-901

    Encorafenib

    Encorafenib

    Encorafenib

  • Nintedanib

    • Chemical compound

    (GPE, (1-3)IGF-1) Trofinetide LNGF (p75NTR) Agonists: BDNF BNN-20 BNN-27 Cenegermin DHEA DHEA-S NGF NT-3 NT-4 Antagonists: ALE-0540 Dexamethasone EVT-901

    Nintedanib

    Nintedanib

    Nintedanib

  • Alectinib

    • ALK inhibitor for treatment of non-small-cell lung cancer

    (GPE, (1-3)IGF-1) Trofinetide LNGF (p75NTR) Agonists: BDNF BNN-20 BNN-27 Cenegermin DHEA DHEA-S NGF NT-3 NT-4 Antagonists: ALE-0540 Dexamethasone EVT-901

    Alectinib

    Alectinib

    Alectinib

  • Pegfilgrastim

    • Monoclonal antibody

    (GPE, (1-3)IGF-1) Trofinetide LNGF (p75NTR) Agonists: BDNF BNN-20 BNN-27 Cenegermin DHEA DHEA-S NGF NT-3 NT-4 Antagonists: ALE-0540 Dexamethasone EVT-901

    Pegfilgrastim

    Pegfilgrastim

  • Avutometinib/defactinib

    • Combination cancer medication

    (GPE, (1-3)IGF-1) Trofinetide LNGF (p75NTR) Agonists: BDNF BNN-20 BNN-27 Cenegermin DHEA DHEA-S NGF NT-3 NT-4 Antagonists: ALE-0540 Dexamethasone EVT-901

    Avutometinib/defactinib

    Avutometinib/defactinib

  • Dehydroepiandrosterone

    • Chemical compound

    (GPE, (1-3)IGF-1) Trofinetide LNGF (p75NTR) Agonists: BDNF BNN-20 BNN-27 Cenegermin DHEA DHEA-S NGF NT-3 NT-4 Antagonists: ALE-0540 Dexamethasone EVT-901

    Dehydroepiandrosterone

    Dehydroepiandrosterone

    Dehydroepiandrosterone

  • Tyrosine kinase

    • Enzyme

    (GPE, (1-3)IGF-1) Trofinetide LNGF (p75NTR) Agonists: BDNF BNN-20 BNN-27 Cenegermin DHEA DHEA-S NGF NT-3 NT-4 Antagonists: ALE-0540 Dexamethasone EVT-901

    Tyrosine kinase

    Tyrosine kinase

    Tyrosine_kinase

  • Antineoplastic

    • Class of drugs used to treat malignant tumors

    (GPE, (1-3)IGF-1) Trofinetide LNGF (p75NTR) Agonists: BDNF BNN-20 BNN-27 Cenegermin DHEA DHEA-S NGF NT-3 NT-4 Antagonists: ALE-0540 Dexamethasone EVT-901

    Antineoplastic

    Antineoplastic

    Antineoplastic

  • Platelet-derived growth factor

    • Signaling glycoprotein regulating cell proliferation

    (GPE, (1-3)IGF-1) Trofinetide LNGF (p75NTR) Agonists: BDNF BNN-20 BNN-27 Cenegermin DHEA DHEA-S NGF NT-3 NT-4 Antagonists: ALE-0540 Dexamethasone EVT-901

    Platelet-derived growth factor

    Platelet-derived growth factor

    Platelet-derived_growth_factor

  • Neurotrophin

    • Family of proteins

    (GPE, (1-3)IGF-1) Trofinetide LNGF (p75NTR) Agonists: BDNF BNN-20 BNN-27 Cenegermin DHEA DHEA-S NGF NT-3 NT-4 Antagonists: ALE-0540 Dexamethasone EVT-901

    Neurotrophin

    Neurotrophin

    Neurotrophin

  • RAMP1

    • Protein-coding gene in the species Homo sapiens

    (GPE, (1-3)IGF-1) Trofinetide LNGF (p75NTR) Agonists: BDNF BNN-20 BNN-27 Cenegermin DHEA DHEA-S NGF NT-3 NT-4 Antagonists: ALE-0540 Dexamethasone EVT-901

    RAMP1

    RAMP1

    RAMP1

  • Lorlatinib

    • Kinase inhibitor for treatment of non-small-cell lung cancer

    (GPE, (1-3)IGF-1) Trofinetide LNGF (p75NTR) Agonists: BDNF BNN-20 BNN-27 Cenegermin DHEA DHEA-S NGF NT-3 NT-4 Antagonists: ALE-0540 Dexamethasone EVT-901

    Lorlatinib

    Lorlatinib

    Lorlatinib

  • Pazopanib

    • Chemical compound

    (GPE, (1-3)IGF-1) Trofinetide LNGF (p75NTR) Agonists: BDNF BNN-20 BNN-27 Cenegermin DHEA DHEA-S NGF NT-3 NT-4 Antagonists: ALE-0540 Dexamethasone EVT-901

    Pazopanib

    Pazopanib

  • Hepatocyte growth factor

    • Mammalian protein found in Homo sapiens

    (GPE, (1-3)IGF-1) Trofinetide LNGF (p75NTR) Agonists: BDNF BNN-20 BNN-27 Cenegermin DHEA DHEA-S NGF NT-3 NT-4 Antagonists: ALE-0540 Dexamethasone EVT-901

    Hepatocyte growth factor

    Hepatocyte_growth_factor

  • Fibroblast growth factor

    • Family of proteins involved in anatomical development

    (GPE, (1-3)IGF-1) Trofinetide LNGF (p75NTR) Agonists: BDNF BNN-20 BNN-27 Cenegermin DHEA DHEA-S NGF NT-3 NT-4 Antagonists: ALE-0540 Dexamethasone EVT-901

    Fibroblast growth factor

    Fibroblast_growth_factor

  • EPHA10

    • Protein-coding gene in the species Homo sapiens

    (GPE, (1-3)IGF-1) Trofinetide LNGF (p75NTR) Agonists: BDNF BNN-20 BNN-27 Cenegermin DHEA DHEA-S NGF NT-3 NT-4 Antagonists: ALE-0540 Dexamethasone EVT-901

    EPHA10

    EPHA10

    EPHA10

  • Crizotinib

    • ALK inhibitor for treatment of non-small-cell lung cancer

    (GPE, (1-3)IGF-1) Trofinetide LNGF (p75NTR) Agonists: BDNF BNN-20 BNN-27 Cenegermin DHEA DHEA-S NGF NT-3 NT-4 Antagonists: ALE-0540 Dexamethasone EVT-901

    Crizotinib

    Crizotinib

    Crizotinib

  • GFRA1

    • Protein-coding gene in the species Homo sapiens

    (GPE, (1-3)IGF-1) Trofinetide LNGF (p75NTR) Agonists: BDNF BNN-20 BNN-27 Cenegermin DHEA DHEA-S NGF NT-3 NT-4 Antagonists: ALE-0540 Dexamethasone EVT-901

    GFRA1

    GFRA1

    GFRA1

  • Mecasermin

    • Pharmaceutical drug

    (GPE, (1-3)IGF-1) Trofinetide LNGF (p75NTR) Agonists: BDNF BNN-20 BNN-27 Cenegermin DHEA DHEA-S NGF NT-3 NT-4 Antagonists: ALE-0540 Dexamethasone EVT-901

    Mecasermin

    Mecasermin

  • Dabrafenib

    • Anti-cancer medication

    (GPE, (1-3)IGF-1) Trofinetide LNGF (p75NTR) Agonists: BDNF BNN-20 BNN-27 Cenegermin DHEA DHEA-S NGF NT-3 NT-4 Antagonists: ALE-0540 Dexamethasone EVT-901

    Dabrafenib

    Dabrafenib

    Dabrafenib

  • Lenvatinib

    • Chemical compound

    (GPE, (1-3)IGF-1) Trofinetide LNGF (p75NTR) Agonists: BDNF BNN-20 BNN-27 Cenegermin DHEA DHEA-S NGF NT-3 NT-4 Antagonists: ALE-0540 Dexamethasone EVT-901

    Lenvatinib

    Lenvatinib

    Lenvatinib

  • VEGF receptor

    • Protein family

    (GPE, (1-3)IGF-1) Trofinetide LNGF (p75NTR) Agonists: BDNF BNN-20 BNN-27 Cenegermin DHEA DHEA-S NGF NT-3 NT-4 Antagonists: ALE-0540 Dexamethasone EVT-901

    VEGF receptor

    VEGF receptor

    VEGF_receptor

  • Cabozantinib

    • Chemical compound

    (GPE, (1-3)IGF-1) Trofinetide LNGF (p75NTR) Agonists: BDNF BNN-20 BNN-27 Cenegermin DHEA DHEA-S NGF NT-3 NT-4 Antagonists: ALE-0540 Dexamethasone EVT-901

    Cabozantinib

    Cabozantinib

    Cabozantinib

  • Tropoflavin

    • Chemical compound

    (GPE, (1-3)IGF-1) Trofinetide LNGF (p75NTR) Agonists: BDNF BNN-20 BNN-27 Cenegermin DHEA DHEA-S NGF NT-3 NT-4 Antagonists: ALE-0540 Dexamethasone EVT-901

    Tropoflavin

    Tropoflavin

    Tropoflavin

  • Adult neurogenesis

    • Generating of neurons from neural stem cells in adults

    (GPE, (1-3)IGF-1) Trofinetide LNGF (p75NTR) Agonists: BDNF BNN-20 BNN-27 Cenegermin DHEA DHEA-S NGF NT-3 NT-4 Antagonists: ALE-0540 Dexamethasone EVT-901

    Adult neurogenesis

    Adult neurogenesis

    Adult_neurogenesis

  • Trastuzumab emtansine

    • Pharmaceutical drug

    (GPE, (1-3)IGF-1) Trofinetide LNGF (p75NTR) Agonists: BDNF BNN-20 BNN-27 Cenegermin DHEA DHEA-S NGF NT-3 NT-4 Antagonists: ALE-0540 Dexamethasone EVT-901

    Trastuzumab emtansine

    Trastuzumab emtansine

    Trastuzumab_emtansine

  • Erlotinib

    • Medication for treatment of non-small-cell lung cancer

    (GPE, (1-3)IGF-1) Trofinetide LNGF (p75NTR) Agonists: BDNF BNN-20 BNN-27 Cenegermin DHEA DHEA-S NGF NT-3 NT-4 Antagonists: ALE-0540 Dexamethasone EVT-901

    Erlotinib

    Erlotinib

    Erlotinib

  • Ponazuril

    • Chemical compound

    (GPE, (1-3)IGF-1) Trofinetide LNGF (p75NTR) Agonists: BDNF BNN-20 BNN-27 Cenegermin DHEA DHEA-S NGF NT-3 NT-4 Antagonists: ALE-0540 Dexamethasone EVT-901

    Ponazuril

    Ponazuril

    Ponazuril

  • Ranibizumab

    • Pharmaceutical drug

    (GPE, (1-3)IGF-1) Trofinetide LNGF (p75NTR) Agonists: BDNF BNN-20 BNN-27 Cenegermin DHEA DHEA-S NGF NT-3 NT-4 Antagonists: ALE-0540 Dexamethasone EVT-901

    Ranibizumab

    Ranibizumab

  • Epidermal growth factor receptor

    • Transmembrane protein

    (GPE, (1-3)IGF-1) Trofinetide LNGF (p75NTR) Agonists: BDNF BNN-20 BNN-27 Cenegermin DHEA DHEA-S NGF NT-3 NT-4 Antagonists: ALE-0540 Dexamethasone EVT-901

    Epidermal growth factor receptor

    Epidermal growth factor receptor

    Epidermal_growth_factor_receptor

  • Pertuzumab

    • Pharmaceutical drug

    (GPE, (1-3)IGF-1) Trofinetide LNGF (p75NTR) Agonists: BDNF BNN-20 BNN-27 Cenegermin DHEA DHEA-S NGF NT-3 NT-4 Antagonists: ALE-0540 Dexamethasone EVT-901

    Pertuzumab

    Pertuzumab

    Pertuzumab

  • RAMP3

    • Protein-coding gene in the species Homo sapiens

    (GPE, (1-3)IGF-1) Trofinetide LNGF (p75NTR) Agonists: BDNF BNN-20 BNN-27 Cenegermin DHEA DHEA-S NGF NT-3 NT-4 Antagonists: ALE-0540 Dexamethasone EVT-901

    RAMP3

    RAMP3

    RAMP3

  • Gefitinib

    • Medication used for cancer

    (GPE, (1-3)IGF-1) Trofinetide LNGF (p75NTR) Agonists: BDNF BNN-20 BNN-27 Cenegermin DHEA DHEA-S NGF NT-3 NT-4 Antagonists: ALE-0540 Dexamethasone EVT-901

    Gefitinib

    Gefitinib

    Gefitinib

  • RET proto-oncogene

    • Mammalian protein

    (GPE, (1-3)IGF-1) Trofinetide LNGF (p75NTR) Agonists: BDNF BNN-20 BNN-27 Cenegermin DHEA DHEA-S NGF NT-3 NT-4 Antagonists: ALE-0540 Dexamethasone EVT-901

    RET proto-oncogene

    RET proto-oncogene

    RET_proto-oncogene

  • Sorafenib

    • Cancer treatment medicine

    (GPE, (1-3)IGF-1) Trofinetide LNGF (p75NTR) Agonists: BDNF BNN-20 BNN-27 Cenegermin DHEA DHEA-S NGF NT-3 NT-4 Antagonists: ALE-0540 Dexamethasone EVT-901

    Sorafenib

    Sorafenib

    Sorafenib

  • Amivantamab/hyaluronidase

    • Medication

    (GPE, (1-3)IGF-1) Trofinetide LNGF (p75NTR) Agonists: BDNF BNN-20 BNN-27 Cenegermin DHEA DHEA-S NGF NT-3 NT-4 Antagonists: ALE-0540 Dexamethasone EVT-901

    Amivantamab/hyaluronidase

    Amivantamab/hyaluronidase

  • Hemopoietic growth factor

    • Class of proteins

    (GPE, (1-3)IGF-1) Trofinetide LNGF (p75NTR) Agonists: BDNF BNN-20 BNN-27 Cenegermin DHEA DHEA-S NGF NT-3 NT-4 Antagonists: ALE-0540 Dexamethasone EVT-901

    Hemopoietic growth factor

    Hemopoietic_growth_factor

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