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Organic compounds
Amidines are organic compounds with the functional group RC(NR)NR2, where the R groups can be the same or different. They are the imine derivatives of
Amidine
Chemical compound
more commonly DBU, is a chemical compound and belongs to the class of amidine compounds. It is used in organic synthesis as a catalyst, a complexing
1,8-Diazabicyclo(5.4.0)undec-7-ene
1,8-Diazabicyclo(5.4.0)undec-7-ene
Chemical compound
N’-tetramethylchloroformamidinium hexafluorophosphate) is an electrophilic amidine reagent used to activate a number of functional groups (such as carboxylic
TCFH
Reaction of cyanide and alcohol to give imino ester salt
excess of alcohol to form an orthoester With ammonia or an amine to form an amidine (di-nitriles may form imidines, for instance succinimidine from succinonitrile)
Pinner_reaction
Aromatic compound (C4H4N2)
Pinner, who synthesized derivatives by condensing ethyl acetoacetate with amidines. Pinner first proposed the name “pyrimidin” in 1885. The parent compound
Pyrimidine
Chemical compound
conjugate addition of the amidine nitrogen to the malononitrile followed by loss of ethoxide (3); addition of the remaining amidine nitrogen to one of the
Amprolium
Pharmaceutical compound
BB-Cl-Amidine is an experimental drug which acts as a non-subtype selective, irreversible inhibitor of the enzyme peptidylarginine deiminase (PAD). It
BB-Cl-Amidine
Organic compound
Enamine Ammonium Hydrazo Nitrene Imine Oxime Hydrazone Azo Amide Imidate Amidine Carbamate Imide Nitrile Isonitrile Cyanate Isocyanate Nitrate Nitrite Nitro
Urea
Enzyme
that the rodent proteins are special. Irreversible inhibitors Cl-amidine, BB-Cl-Amidine, YW3-56 Reversible inhibitors GSK484, GSK199 Sams, K.L; Mukai, C;
Protein-arginine_deiminase
Chemical compound
0]non-5-ene (DBN) is a chemical compound with the formula C7H12N2. It is an amidine base used in organic synthesis. A related compound with related functions
1,5-Diazabicyclo(4.3.0)non-5-ene
1,5-Diazabicyclo(4.3.0)non-5-ene
Anti-parasite drug with a di-amidine
certain bacteria including Brucella and Streptococcus. Chemically it is a di-amidine and it is formulated as its aceturate salt, diminazene aceturate. The mechanism
Diminazene
Chemical compound
dihydrochloride salt. It binds free amino groups at pH range 7.0-10.0 to form amidine bonds. DMP is used mainly as bifunctional coupling reagent to link proteins
Dimethyl_pimelimidate
Organic compounds of the form >C=O
Enamine Ammonium Hydrazo Nitrene Imine Oxime Hydrazone Azo Amide Imidate Amidine Carbamate Imide Nitrile Isonitrile Cyanate Isocyanate Nitrate Nitrite Nitro
Ketone
Chemical compound
compounds. It is the hydrochloride of acetamidine, one of the simplest amidines. Acetamidine hydrochloride is a hygroscopic solid which forms colourless
Acetamidine_hydrochloride
Group of atoms giving a molecule characteristic properties
carboxamido- or carbamoyl- -amide Acetamide (Ethanamide) Amidine Amidine R4C(NR1)(NR2R3) amidino- -amidine acetamidine (acetimidamide) Guanidine Guanidine RNC(NR2)2
Functional_group
Chemical compound
Enamine Ammonium Hydrazo Nitrene Imine Oxime Hydrazone Azo Amide Imidate Amidine Carbamate Imide Nitrile Isonitrile Cyanate Isocyanate Nitrate Nitrite Nitro
Glycidamide
Chemical compounds with the structure R–O–O–R'
Enamine Ammonium Hydrazo Nitrene Imine Oxime Hydrazone Azo Amide Imidate Amidine Carbamate Imide Nitrile Isonitrile Cyanate Isocyanate Nitrate Nitrite Nitro
Peroxide
Chemical compound
have been explored. The structure of bottromycin contains a macrocyclic amidine as well as a thiazole ring. The absolute stereochemistry at several chiral
Bottromycin
Extremely strong base
kcal/mol) than proton sponge. Common superbases of this variety feature amidine, guanidine, and phosphazene functional groups. Strong superbases can be
Superbase
carbon-nitrogen bonds other than peptide bonds, specifically in cyclic amidines. The systematic name of this enzyme class is sepiapterin aminohydrolase
Sepiapterin_deaminase
Chemical group (–CH2–C6H5)
Enamine Ammonium Hydrazo Nitrene Imine Oxime Hydrazone Azo Amide Imidate Amidine Carbamate Imide Nitrile Isonitrile Cyanate Isocyanate Nitrate Nitrite Nitro
Benzyl_group
Chemical group (R–O)
Enamine Ammonium Hydrazo Nitrene Imine Oxime Hydrazone Azo Amide Imidate Amidine Carbamate Imide Nitrile Isonitrile Cyanate Isocyanate Nitrate Nitrite Nitro
Alkoxy_group
Chemical compound
this group is that of an imine, and the group is related structurally to amidines and ureas. Examples of guanidines are arginine, triazabicyclodecene, saxitoxin
Guanidine
Organic compound containing C–PO(OR)2 groups
Enamine Ammonium Hydrazo Nitrene Imine Oxime Hydrazone Azo Amide Imidate Amidine Carbamate Imide Nitrile Isonitrile Cyanate Isocyanate Nitrate Nitrite Nitro
Phosphonate
Class of organic compounds
Enamine Ammonium Hydrazo Nitrene Imine Oxime Hydrazone Azo Amide Imidate Amidine Carbamate Imide Nitrile Isonitrile Cyanate Isocyanate Nitrate Nitrite Nitro
Hydrazone
Chemical compound
2-Iminothiolane reacts with primary amines efficiently at pH 7 to 9, creating amidine compounds with a sulfhydryl group. Thus it allows for crosslinking or labeling
2-Iminothiolane
Chemical compounds and groups containing nitrogen with a lone pair (:N)
Enamine Ammonium Hydrazo Nitrene Imine Oxime Hydrazone Azo Amide Imidate Amidine Carbamate Imide Nitrile Isonitrile Cyanate Isocyanate Nitrate Nitrite Nitro
Amine
Chemical compound
organic compound with the formula C6H5C(NH)NH2. It is the simplest aryl amidine. The compound is a white solid that is slightly soluble in water. It is
Benzamidine
Any organic compound having a sulfanyl group (–SH)
Enamine Ammonium Hydrazo Nitrene Imine Oxime Hydrazone Azo Amide Imidate Amidine Carbamate Imide Nitrile Isonitrile Cyanate Isocyanate Nitrate Nitrite Nitro
Thiol
Chemical reaction
Enamine Ammonium Hydrazo Nitrene Imine Oxime Hydrazone Azo Amide Imidate Amidine Carbamate Imide Nitrile Isonitrile Cyanate Isocyanate Nitrate Nitrite Nitro
Hydrodealkylation
Class of chemical compounds
Enamine Ammonium Hydrazo Nitrene Imine Oxime Hydrazone Azo Amide Imidate Amidine Carbamate Imide Nitrile Isonitrile Cyanate Isocyanate Nitrate Nitrite Nitro
Selenol
Chemical group (–OC(O)CH3)
Enamine Ammonium Hydrazo Nitrene Imine Oxime Hydrazone Azo Amide Imidate Amidine Carbamate Imide Nitrile Isonitrile Cyanate Isocyanate Nitrate Nitrite Nitro
Acetoxy_group
Chemical group, –C(=O)CH3
Enamine Ammonium Hydrazo Nitrene Imine Oxime Hydrazone Azo Amide Imidate Amidine Carbamate Imide Nitrile Isonitrile Cyanate Isocyanate Nitrate Nitrite Nitro
Acetyl_group
Chemical group (–OH)
Enamine Ammonium Hydrazo Nitrene Imine Oxime Hydrazone Azo Amide Imidate Amidine Carbamate Imide Nitrile Isonitrile Cyanate Isocyanate Nitrate Nitrite Nitro
Hydroxy_group
Organosulfur compound of the form R–SOH
Enamine Ammonium Hydrazo Nitrene Imine Oxime Hydrazone Azo Amide Imidate Amidine Carbamate Imide Nitrile Isonitrile Cyanate Isocyanate Nitrate Nitrite Nitro
Sulfenic_acid
Chemical compound
Intermediate aryl amidine (2) is prepared by aluminium trichloride-catalyzed addition of aniline to the nitrile of 4-cyanothiazole (1). The amidine (2) is then
Tiabendazole
Organic compounds of the form R–O–O–R′
Enamine Ammonium Hydrazo Nitrene Imine Oxime Hydrazone Azo Amide Imidate Amidine Carbamate Imide Nitrile Isonitrile Cyanate Isocyanate Nitrate Nitrite Nitro
Organic_peroxides
Antidepressant compound
contains three functional groups: a nitrobenzene, a furan ring and an amidine. Azo coupling between 2-nitrophenyldiazonium chloride [119-66-4] (1) and
Nitrafudam
Organic compounds with a carbon-carbon-oxygen ring
Enamine Ammonium Hydrazo Nitrene Imine Oxime Hydrazone Azo Amide Imidate Amidine Carbamate Imide Nitrile Isonitrile Cyanate Isocyanate Nitrate Nitrite Nitro
Epoxide
Functional group with the chemical structure R–S–S–R′
Enamine Ammonium Hydrazo Nitrene Imine Oxime Hydrazone Azo Amide Imidate Amidine Carbamate Imide Nitrile Isonitrile Cyanate Isocyanate Nitrate Nitrite Nitro
Disulfide
Chemical group (–CH=CH2)
Enamine Ammonium Hydrazo Nitrene Imine Oxime Hydrazone Azo Amide Imidate Amidine Carbamate Imide Nitrile Isonitrile Cyanate Isocyanate Nitrate Nitrite Nitro
Vinyl_group
Medication that reduces stomach acid
Famotidine, sold under the brand name Pepcid among others, is a histamine H2 receptor antagonist medication that decreases stomach acid production. It
Famotidine
Any part of a molecule with the chemical formula –CH2–
Enamine Ammonium Hydrazo Nitrene Imine Oxime Hydrazone Azo Amide Imidate Amidine Carbamate Imide Nitrile Isonitrile Cyanate Isocyanate Nitrate Nitrite Nitro
Methylene_bridge
Urinary antiseptic drug
derivatives Ethacridine lactate 9-Aminoacridine Euflavine Biguanides and amidines Dibrompropamidine Chlorhexidine# Propamidine Hexamidine Polihexanide Phenol
Methenamine
Simplest secondary alcohol
derivatives Ethacridine lactate 9-Aminoacridine Euflavine Biguanides and amidines Dibrompropamidine Chlorhexidine# Propamidine Hexamidine Polihexanide Phenol
Isopropyl_alcohol
Compound derived from an acid
Enamine Ammonium Hydrazo Nitrene Imine Oxime Hydrazone Azo Amide Imidate Amidine Carbamate Imide Nitrile Isonitrile Cyanate Isocyanate Nitrate Nitrite Nitro
Ester
Organic compounds made of alkyl/aryl groups bound to oxygen (R–O–R')
Enamine Ammonium Hydrazo Nitrene Imine Oxime Hydrazone Azo Amide Imidate Amidine Carbamate Imide Nitrile Isonitrile Cyanate Isocyanate Nitrate Nitrite Nitro
Ether
Organic molecule with two different functional groups
Enamine Ammonium Hydrazo Nitrene Imine Oxime Hydrazone Azo Amide Imidate Amidine Carbamate Imide Nitrile Isonitrile Cyanate Isocyanate Nitrate Nitrite Nitro
Bifunctionality
Chemical property
R. Caminiti, A. Pieretti, L. Bencivenni, F. Ramondo, N. Sanna (1996). "Amidine N−C(N)−N Skeleton: Its Structure in Isolated and Hydrogen-Bonded Guanidines
Aromaticity
Cyclic chemical group (–C6H5)
Enamine Ammonium Hydrazo Nitrene Imine Oxime Hydrazone Azo Amide Imidate Amidine Carbamate Imide Nitrile Isonitrile Cyanate Isocyanate Nitrate Nitrite Nitro
Phenyl_group
Veterinary medical products classification subgroup
ATCvet code QP53 Ectoparasiticides, including insecticides and repellents is a therapeutic subgroup of the Anatomical Therapeutic Chemical Classification
ATCvet_code_QP53
Organic compounds of the form RC(=O)NR′R″
Enamine Ammonium Hydrazo Nitrene Imine Oxime Hydrazone Azo Amide Imidate Amidine Carbamate Imide Nitrile Isonitrile Cyanate Isocyanate Nitrate Nitrite Nitro
Amide
Surfactant and antiseptic agent
derivatives Ethacridine lactate 9-Aminoacridine Euflavine Biguanides and amidines Dibrompropamidine Chlorhexidine# Propamidine Hexamidine Polihexanide Phenol
Benzalkonium_chloride
Species of flowering plant in the nightshade family
tetrahydroharmine, harmaline, manacin, manacein, and dimethyltryptamine and amidine derivatives such as pyrrole 3-carboxamidine. Cultivated plant, Chicago
Brunfelsia_pauciflora
Organic compound (C6H5OH)
derivatives Ethacridine lactate 9-Aminoacridine Euflavine Biguanides and amidines Dibrompropamidine Chlorhexidine# Propamidine Hexamidine Polihexanide Phenol
Phenol
carbon-nitrogen bonds other than peptide bonds, specifically in cyclic amidines. The systematic name of this enzyme class is guanosine aminohydrolase.
Guanosine_deaminase
Enamine Ammonium Hydrazo Nitrene Imine Oxime Hydrazone Azo Amide Imidate Amidine Carbamate Imide Nitrile Isonitrile Cyanate Isocyanate Nitrate Nitrite Nitro
Amide_(functional_group)
Enamine Ammonium Hydrazo Nitrene Imine Oxime Hydrazone Azo Amide Imidate Amidine Carbamate Imide Nitrile Isonitrile Cyanate Isocyanate Nitrate Nitrite Nitro
Reductone
Organic compound containing a –C(=O)OH group
Enamine Ammonium Hydrazo Nitrene Imine Oxime Hydrazone Azo Amide Imidate Amidine Carbamate Imide Nitrile Isonitrile Cyanate Isocyanate Nitrate Nitrite Nitro
Carboxylic_acid
Antimicrobial agent that inactivates or destroys microbes
derivatives Ethacridine lactate 9-Aminoacridine Euflavine Biguanides and amidines Dibrompropamidine Chlorhexidine# Propamidine Hexamidine Polihexanide Phenol
Disinfectant
Quaternary ammonium surfactant and antiseptic agent
derivatives Ethacridine lactate 9-Aminoacridine Euflavine Biguanides and amidines Dibrompropamidine Chlorhexidine# Propamidine Hexamidine Polihexanide Phenol
Cetrimonium_bromide
semicorrins are characterized by a rigid framework containing a vinylogous amidine system embedded in a bicyclic structure. Semicorrins have been designed
Semicorrin
Benzodiazepine
of bromazepam (1) with methylamine and titanium tetrachloride gives the amidine (2). Treatment with nitrous acid gives the nitrosylation product (3). Further
Pyrazolam
Chemical compound
Phenamidine is an antiprotozoal drug of the amidine class used in veterinary medicine. It is used to treat Babesia infection (babesiosis) dogs, horses
Phenamidine
Chemical compound
derivatives Ethacridine lactate 9-Aminoacridine Euflavine Biguanides and amidines Dibrompropamidine Chlorhexidine# Propamidine Hexamidine Polihexanide Phenol
Hydrogen_peroxide
Hydrocarbon compound (H2C=CH2)
Enamine Ammonium Hydrazo Nitrene Imine Oxime Hydrazone Azo Amide Imidate Amidine Carbamate Imide Nitrile Isonitrile Cyanate Isocyanate Nitrate Nitrite Nitro
Ethylene
Chemical compound
those of other benzodiazepines. Thio thionamide is even more prone to amidine formation than the lactam itself. Reaction of thionamide (2) with O-allyl-hydroxylamine
Uldazepam
Functional group
Enamine Ammonium Hydrazo Nitrene Imine Oxime Hydrazone Azo Amide Imidate Amidine Carbamate Imide Nitrile Isonitrile Cyanate Isocyanate Nitrate Nitrite Nitro
Methylenedioxy
Chemical group (>N–C(=O)–O–)
Enamine Ammonium Hydrazo Nitrene Imine Oxime Hydrazone Azo Amide Imidate Amidine Carbamate Imide Nitrile Isonitrile Cyanate Isocyanate Nitrate Nitrite Nitro
Carbamate
Organic compound containing the functional group R–CH=O
Enamine Ammonium Hydrazo Nitrene Imine Oxime Hydrazone Azo Amide Imidate Amidine Carbamate Imide Nitrile Isonitrile Cyanate Isocyanate Nitrate Nitrite Nitro
Aldehyde
Hydrocarbon compound (C6H6)
Enamine Ammonium Hydrazo Nitrene Imine Oxime Hydrazone Azo Amide Imidate Amidine Carbamate Imide Nitrile Isonitrile Cyanate Isocyanate Nitrate Nitrite Nitro
Benzene
Naturally occurring sedative and hallucinogen
Nielsen B, et al. (2016). Synthesis and Pharmacological Evaluation of Amidine Containing GABAA Receptor Agonists (PDF). EFMC International Symposium
Muscimol
Oxidation reaction in organic chemistry
chemistry, the Graham reaction is an oxidation reaction that converts an amidine into a diazirine using a hypohalite reagent. The halide of the hypohalite
Graham_reaction
Chemical compound
synthesis (named after Adolf Pinner) the reactants are an alkyl or aryl amidine and phosgene. Insertion of an N-H moiety into a hydrazide by a copper carbenoid
1,3,5-Triazine
Chemical compound
is likely similar to the Pinner reaction; preceding via an intermediate amidine. Limited research has been done into identifying alternative solvents or
Oxazoline
Chemical compound
derivatives Ethacridine lactate 9-Aminoacridine Euflavine Biguanides and amidines Dibrompropamidine Chlorhexidine# Propamidine Hexamidine Polihexanide Phenol
Sodium_hypochlorite
Antiseptic solution
derivatives Ethacridine lactate 9-Aminoacridine Euflavine Biguanides and amidines Dibrompropamidine Chlorhexidine# Propamidine Hexamidine Polihexanide Phenol
Povidone-iodine
Chemical group derived from alkanes (one hydrogen removed)
Enamine Ammonium Hydrazo Nitrene Imine Oxime Hydrazone Azo Amide Imidate Amidine Carbamate Imide Nitrile Isonitrile Cyanate Isocyanate Nitrate Nitrite Nitro
Alkyl_group
Functional group (C=O)
Enamine Ammonium Hydrazo Nitrene Imine Oxime Hydrazone Azo Amide Imidate Amidine Carbamate Imide Nitrile Isonitrile Cyanate Isocyanate Nitrate Nitrite Nitro
Carbonyl_group
Class of organic compounds
Enamine Ammonium Hydrazo Nitrene Imine Oxime Hydrazone Azo Amide Imidate Amidine Carbamate Imide Nitrile Isonitrile Cyanate Isocyanate Nitrate Nitrite Nitro
Chlorofluorocarbon
Class of chemical compounds
Enamine Ammonium Hydrazo Nitrene Imine Oxime Hydrazone Azo Amide Imidate Amidine Carbamate Imide Nitrile Isonitrile Cyanate Isocyanate Nitrate Nitrite Nitro
Hydroperoxide
Heterocyclic aromatic organic compound
Enamine Ammonium Hydrazo Nitrene Imine Oxime Hydrazone Azo Amide Imidate Amidine Carbamate Imide Nitrile Isonitrile Cyanate Isocyanate Nitrate Nitrite Nitro
Pyridine
Chemical compound
derivatives Ethacridine lactate 9-Aminoacridine Euflavine Biguanides and amidines Dibrompropamidine Chlorhexidine# Propamidine Hexamidine Polihexanide Phenol
Benzethonium_chloride
Hydrocarbon compound containing one or more C=C bonds
Enamine Ammonium Hydrazo Nitrene Imine Oxime Hydrazone Azo Amide Imidate Amidine Carbamate Imide Nitrile Isonitrile Cyanate Isocyanate Nitrate Nitrite Nitro
Alkene
Chemical group (–C3H7) derived from propane
Enamine Ammonium Hydrazo Nitrene Imine Oxime Hydrazone Azo Amide Imidate Amidine Carbamate Imide Nitrile Isonitrile Cyanate Isocyanate Nitrate Nitrite Nitro
Propyl_group
Free radical
Enamine Ammonium Hydrazo Nitrene Imine Oxime Hydrazone Azo Amide Imidate Amidine Carbamate Imide Nitrile Isonitrile Cyanate Isocyanate Nitrate Nitrite Nitro
Propenyl_group
Atypical antipsychotic medication
Olanzapine, sold under the brand name Zyprexa among others, is an atypical antipsychotic primarily used to treat schizophrenia and bipolar disorder. It
Olanzapine
Organic compound with at least one hydroxyl (–OH) group
Enamine Ammonium Hydrazo Nitrene Imine Oxime Hydrazone Azo Amide Imidate Amidine Carbamate Imide Nitrile Isonitrile Cyanate Isocyanate Nitrate Nitrite Nitro
Alcohol_(chemistry)
Chemical compound
binding to the small furrow of the double helix. Distamycin is a pyrrole-amidine antibiotic and analogous to netropsin and the class of lexitropsins. As
Distamycin
Drug discovery
selective binding to FXa. Those early developed small molecules yet had amidine-groups or even higher-basic functions, which were thought to be necessary
Discovery and development of direct Xa inhibitors
Discovery_and_development_of_direct_Xa_inhibitors
Chemical group
Enamine Ammonium Hydrazo Nitrene Imine Oxime Hydrazone Azo Amide Imidate Amidine Carbamate Imide Nitrile Isonitrile Cyanate Isocyanate Nitrate Nitrite Nitro
Sulfonanilide
Chemical compound containing carbon and at least one halogen
Enamine Ammonium Hydrazo Nitrene Imine Oxime Hydrazone Azo Amide Imidate Amidine Carbamate Imide Nitrile Isonitrile Cyanate Isocyanate Nitrate Nitrite Nitro
Halocarbon
Organic compound with the structure >C(O–)2
Enamine Ammonium Hydrazo Nitrene Imine Oxime Hydrazone Azo Amide Imidate Amidine Carbamate Imide Nitrile Isonitrile Cyanate Isocyanate Nitrate Nitrite Nitro
Acetal
Chemical group (–CH3) derived from methane
Enamine Ammonium Hydrazo Nitrene Imine Oxime Hydrazone Azo Amide Imidate Amidine Carbamate Imide Nitrile Isonitrile Cyanate Isocyanate Nitrate Nitrite Nitro
Methyl_group
Chemical group (–CH2–)
Enamine Ammonium Hydrazo Nitrene Imine Oxime Hydrazone Azo Amide Imidate Amidine Carbamate Imide Nitrile Isonitrile Cyanate Isocyanate Nitrate Nitrite Nitro
Methylene_group
Chemical group made of an –S(=O)2 group bound to a halogen
Enamine Ammonium Hydrazo Nitrene Imine Oxime Hydrazone Azo Amide Imidate Amidine Carbamate Imide Nitrile Isonitrile Cyanate Isocyanate Nitrate Nitrite Nitro
Sulfonyl_halide
Class of chemical compounds
Enamine Ammonium Hydrazo Nitrene Imine Oxime Hydrazone Azo Amide Imidate Amidine Carbamate Imide Nitrile Isonitrile Cyanate Isocyanate Nitrate Nitrite Nitro
Seleninic_acid
Chemical compound
from phosphoribosyl-N-formylglycineamide (FGAR) which is converted to an amidine by the action of phosphoribosylformylglycinamidine synthase (EC 6.3.5.3)
5′-Phosphoribosylformylglycinamidine
5′-Phosphoribosylformylglycinamidine
Type of organosulfur compound
Enamine Ammonium Hydrazo Nitrene Imine Oxime Hydrazone Azo Amide Imidate Amidine Carbamate Imide Nitrile Isonitrile Cyanate Isocyanate Nitrate Nitrite Nitro
Sulfinylamine
moisture sensitive and can be converted into imides upon exposure to water. Amidine Guanidines Pinner, A. (January 1883). "Ueber die Umwandlung der Nitrile
Imidine
AMIDINE
AMIDINE
AMIDINE
AMIDINE
AMIDINE
AMIDINE
AMIDINE
AMIDINE
AMIDINE