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Sperm-meets-egg process
process known as the acrosome reaction, which is the reaction that occurs in the acrosome of the sperm as it approaches the egg. The acrosome is a membrane-bound
Acrosome_reaction
Organelle of sperm cells
the haploid nucleus in the ovum. This shedding of the acrosome, known as the acrosome reaction, can be stimulated in vitro by substances that a sperm
Acrosome
Union of a human egg and sperm
its motility and hyperpolarizes its membrane, preparing it for the acrosome reaction, the enzymatic penetration of the egg's tough membrane, the zona pellucida
Human_fertilization
Union of opposite-sex gametes in sexual reproduction to form a zygote
ZP3 and is important for binding with the sperm and activating the acrosome reaction. ZP3 is sufficient though unnecessary for sperm/egg binding. Two additional
Fertilisation
Penultimate step in the activation of mammalian spermatozoa
female reproductive tract. Sperm must undergo capacitation and the acrosome reaction to be able to penetrate through the outer layers of an oocyte, namely
Capacitation
Glycoprotein layer surrounding the plasma membrane of mammalian oocytes
species-specific fertilization; to prevent polyspermy, and enable the acrosome reaction for the successful adhesion and penetration by the sperm cell. It
Zona_pellucida
Male reproductive cell
spermatozoon approaches the ovum, it undergoes the acrosome reaction in which the membrane surrounding the acrosome fuses with the plasma membrane of the sperm's
Sperm
Antibodies produced against sperm antigens
through the female reproductive tract, inhibiting capacitation and acrosome reaction, impaired fertilization, influence on the implantation process, and
Antisperm_antibodies
Biological process that prevents polyspermy
This is often referred to as zona hardening. Acrosome reaction - The analogous reaction in the acrosome of the sperm Rojas, Japhet; Hinostroza, Fernando;
Cortical_reaction
Protein-coding gene in the species Homo sapiens
glycoprotein in the zona pellucida most important for inducting the acrosome reaction of sperm cells at the beginning of fertilization. X-ray crystallographic
ZP3
Mammalian protein found in Homo sapiens
the ACR gene. Acrosin is released from the acrosome of spermatozoa as a consequence of the acrosome reaction. It aids in the penetration of the Zona Pellucida
Acrosin
In vitro fertilization procedure
that may be transferred to a maternal uterus. With this method, the acrosome reaction is skipped. There are several differences between classic IVF and
Intracytoplasmic sperm injection
Intracytoplasmic_sperm_injection
Method of testing human sperm viability
this test. This test evaluates the acrosome reaction of human spermatozoa. However, the incidence of acrosome reaction in freely swimming human sperm does
Hamster_zona-free_ovum_test
Steroidal alkaloid found in plants of the lily family
to have any effect on the acrosome reaction on its own, but it is able to block the progesterone-induced acrosome reaction. Moreover, veratridine has
Veratridine
Union of an egg and sperm to form a zygote within the female body
oocyte, acrosome reactions and associations, piercings of the oocyte zona pellucida by sperm, and reactions such as the cortical and zona reactions. Sperm
Internal_fertilization
Biological membrane structure
This fusion allows the joining of two distinct structures as in the acrosome reaction during fertilization of an egg by a sperm, or the entry of a virus
Lipid_bilayer
Peripheral membrane protein
et al. (May 2010). "Group X phospholipase A2 is released during sperm acrosome reaction and controls fertility outcome in mice". The Journal of Clinical Investigation
Phospholipase_A2
Series of chemical reactions resulting in a cell response
to fertilize the female gamete, this cell suffers capacitation and acrosome reaction in female reproductive tract. The signaling pathways best described
Biochemical_cascade
education Abstinence, be faithful, use a condom Accidental incest Acrosome Acrosome reaction Acrotomophilia Activin and inhibin Adolescent sexuality Adolescent
Index of human sexuality articles
Index_of_human_sexuality_articles
chemical influence on sperm mobility and velocity. Sperm guidance Acrosome reaction Oocyte Wessel, GM; Brooks, JM; Green, E; Haley, S; Voronina, E; Wong
Egg_jelly
Type of sperm cell motility
encloses the ovum. Hyperactivation could then be followed by the acrosome reaction where the cap-like structure on the head of the cell releases the
Hyperactivation
Protein-coding gene in the species Homo sapiens
membrane cytoplasmic vesicle Biological process positive regulation of acrosome reaction regulation of fertilization Sources:Amigo / QuickGO Orthologs Databases
FAM170B
Mammalian protein found in Homo sapiens
Biological process lipid catabolic process positive regulation of acrosome reaction phosphatidylcholine acyl-chain remodeling retinoid metabolic process
Phospholipase_B
Argentine biologist
CAPZA3 localization reveals temporally discrete events during the acrosome reaction". Journal of Cellular Physiology. 224 (3): 575–580. doi:10.1002/jcp
Pablo_Visconti
Mammalian protein found in Homo sapiens
of Glycodelin-A. It also binds the sperm head, thereby inhibiting acrosome reaction and sperm-egg binding. Upon de-glycosilation, glycodelin F dissociates
Glycodelin
Medical term for reduced sperm motility
with the ovule. Studies in mice have shown that DHA is essential for acrosome reaction and a DHA deficiency results in abnormal sperm morphology, loss of
Asthenozoospermia
Protein-coding gene in the species Homo sapiens
Mammalian testis: a comparative analysis focusing on its presence in the acrosome of spermatids". Biol. Reprod. 74 (5): 816–23. doi:10.1095/biolreprod.105
PRND
Protein-coding gene in the species Homo sapiens
regulation of nitric oxide mediated signal transduction regulation of acrosome reaction negative regulation of peptidase activity negative regulation of peptidyl-tyrosine
SPINK1
Protein-coding gene in the species Homo sapiens
membrane azurophil granule membrane Biological process regulation of acrosome reaction glycoprotein biosynthetic process epithelial cell development penetration
B4GALT1
Mammalian protein found in Homo sapiens
of serine-type endopeptidase activity cornification regulation of acrosome reaction negative regulation of endopeptidase activity Sources:Amigo / QuickGO
LEKTI-2
Inability to reproduce
through the female reproductive tract, inhibiting capacitation and acrosome reaction, impaired fertilization, influence on the implantation process, and
Infertility
Cluster of cells surrounding an oocyte
cumulus oophorus cells accumulate around the oocyte to aid in the acrosome reaction that enables the sperm to penetrate into the oocyte. The proximity
Cumulus_oophorus
Species of rodent
these mobile trains was also found to be influenced by premature acrosome reactions, altruistic acts performed by some spermatozoa for the benefit of
Wood_mouse
Chemical compound
"Effects of Native Human Zona Pellucida Glycoproteins 3 and 4 on Acrosome Reaction and Zona Pellucida Binding of Human Spermatozoa". Biology of Reproduction
Sialyl-Lewis_X
Protein-coding gene in humans
proper shaping of sperm head and acrosome within the testis and possibly has an additional role in the sperm acrosome reaction. An understanding of the role
FYN
Protein-coding gene in the species Homo sapiens
reticulum membrane cytosol Biological process lipid catabolic process acrosome reaction intracellular signal transduction phosphatidylinositol metabolic process
PLCD4
Protein-coding gene in humans
motility- and head-associated functions such as capacitation and the acrosome reaction. AKAP3 has been shown to interact with: AKAP4 GNA13, and PRKAR2A.
AKAP3
Medical condition
through the female reproductive tract, inhibiting capacitation and acrosome reaction, impaired fertilization, influence on the implantation process, and
Male_infertility
Protein-coding gene in the species Homo sapiens
positive regulation of T cell proliferation positive regulation of acrosome reaction acrosomal vesicle exocytosis single fertilization Sources:Amigo /
ZP4
Protein found in humans
cortisol biosynthetic process ion transport positive regulation of acrosome reaction cellular response to hormone stimulus calcium ion transmembrane transport
Calcium channel, voltage-dependent, T type, alpha 1H subunit
Calcium_channel,_voltage-dependent,_T_type,_alpha_1H_subunit
Protein-coding gene in the species Homo sapiens
acylglycerol catabolic process steroid hormone mediated signaling pathway acrosome reaction sperm capacitation cellular lipid metabolic process medium-chain fatty
ABHD2
Protein-coding gene in the species Homo sapiens
the zona pellucida and functions in secondary binding and penetration of acrosome-reacted spermatozoa. The nascent protein contains a N-terminal signal peptide
ZP2
FAM180A Gene
11 homolog Plays a role in the process of sperm capacitation and acrosome reactions. FANCE Fanconi anemia group E protein Required for the nuclear accumulation
Family with sequence similarity 180A
Family_with_sequence_similarity_180A
Diminished or absent ability of a female to achieve conception
through the female reproductive tract, inhibiting capacitation and acrosome reaction, impairing fertilization, influencing the implantation process, and
Female_infertility
Protein-coding gene in the species Homo sapiens
proteolysis binding of sperm to zona pellucida sperm capacitation acrosome reaction fertilization reproductive process protein processing peptide hormone
PCSK4
Protein-coding gene in the species Homo sapiens
of acrosome reaction negative regulation of peptidase activity negative regulation of serine-type endopeptidase activity spermatogenesis acrosome assembly
SPINK2
Chemical compound
on spermatogenic cell Ca2+ channels and progesterone-induced sperm acrosome reaction". European Journal of Pharmacology. 464 (1): 9–15. doi:10.1016/S0014-2999(03)01351-7
Demethylzeylasteral
Protein-coding gene in the species Homo sapiens
G protein-coupled receptor signaling pathway single fertilization acrosome reaction olfactory learning flagellated sperm motility cellular response to
ADCY3
Protein-coding gene in the species Homo sapiens
multicellular organism development cell differentiation spermatogenesis acrosome reaction penetration of zona pellucida positive regulation of protein processing
TNP2
Protein-coding gene in the species Homo sapiens
M, Mayorga LS (July 2001). "Synaptotagmin VI participates in the acrosome reaction of human spermatozoa". Developmental Biology. 235 (2): 521–9. doi:10
SYT6
American developmental biologist (born 1937)
Related work examined pH and calcium changes governing the sperm acrosome reaction and used electrically permeabilized eggs to measure changes in glucose-6-phosphate
David_Epel
Protein-coding gene in the species Homo sapiens
the egg as, it is the outer acrosomal domain which initiates the acrosome reaction, enabling the sperm to fuse. Vezatin is present in both these domains
VEZT
Protein-coding gene in the species Homo sapiens
clustering chloride transmembrane transport nervous system development acrosome reaction neuromuscular process righting reflex chloride transport neuropeptide
GLRB
Ion channel that conducts protons based on voltage and pH
entry through CatSper, and impairs hyperactivated motility and the acrosome reaction in vitro. These findings support a role for Hv1 in human fertilization
Voltage-gated_proton_channel
Protein-coding gene in the species Homo sapiens
hyperekplexia, a neurologic syndrome associated with an exaggerated startle reaction. Glycine receptor Stiff person syndrome Hyperekplexia GRCh38: Ensembl release
Glycine_receptor,_alpha_1
Enzyme
damaging effects of lipid peroxidation and/or preventing premature acrosome reaction. Alternatively spliced transcript variants encoding different isoforms
Glutathione_peroxidase_5
Protein-coding gene in the species Homo sapiens
egg plasma membrane involved in single fertilization regulation of acrosome reaction binding of sperm to zona pellucida regulation of molecular function
CRISP1
Chemical compound
balance and death in 4–6 minutes. Latrunculin A has been used as acrosome reaction inhibitor of guinea pig in laboratory conditions. Lat-A-induces reduction
Latrunculin
Protein-coding gene in the species Homo sapiens
in stimulation of capacitation and inhibition of the spontaneous acrosome reaction". Molecular Reproduction and Development. 48 (3): 375–82. doi:10
TCP11
American-born biologist
motility and viability of sea urchin sperm by inhibiting spontaneous acrosome reactions. J. Exp. Zool. 226: 431-440. Johnson, C. H., D. L. Clapper, M. W.
Carl_H._Johnson
Protein-coding gene in the species Homo sapiens
"Human SP-10: acrosomal distribution, processing, and fate after the acrosome reaction". Biol. Reprod. 51 (6): 1222–31. doi:10.1095/biolreprod51.6.1222.
ACRV1
Protein-coding gene in the species Homo sapiens
5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular
PLCB1
Protein-coding gene in the species Homo sapiens
fusion to presynaptic active zone membrane response to hydroperoxide acrosome reaction vesicle docking cornified envelope assembly protein complex oligomerization
STX2
Evolutionary biologist
"Fertilization in Oikopleura dioica (Tunicata, Appendicularia): Acrosome reaction, cortical reaction and sperm-egg fusion". Zoomorphology. 108 (4): 229–243. doi:10
Linda_Holland
Protein-coding gene in the species Homo sapiens
PMID 15489334. Cheng GY, Shi JL, Wang M, et al. (2007). "Inhibition of mouse acrosome reaction and sperm-zona pellucida binding by anti-human sperm membrane protein
Sperm-associated_antigen_8
through the female reproductive tract, inhibiting capacitation and acrosome reaction, impaired fertilization, influence on the implantation process, and
Testicular_immunology
with the zona pellucida surrounding the mature oocyte; the resulting acrosome reaction breaks down the ovum's tough coating so that the sperm and ovum unite
Reproductive_immunology
Protein-coding gene in the species Homo sapiens
for the combined assessment of human sperm acrosome integrity and ionophore A23187-induced acrosome reaction". PLOS ONE. 6 (2) e16985. Bibcode:2011PLoSO
VDAC2
Protein-coding gene in the species Homo sapiens
maturation through the epididymis, capacitation, hypermotility, and/or the acrosome reaction. Mutations in the ADCY10 gene are associated with an increased risk
ADCY10
Indian biologist (1930–2012)
"Induction of buffalo (Bubalus bubalis ) sperm capacitation and acrosome reaction in the excised reproductive tract of hamsters". Theriogenology. 44
Sardul_Singh_Guraya
520.277.800 – sperm-ovum interactions MeSH G08.520.277.800.100 – acrosome reaction MeSH G08.520.277.820 – sperm transport MeSH G08.520.310.500 – oogenesis
List_of_MeSH_codes_(G08)
Protein-coding gene in the species Homo sapiens
sperm zona pellucida binding protein and localization during the acrosome reaction". Dev. Biol. 165 (2): 688–701. doi:10.1006/dbio.1994.1285. PMID 7525387
SPA17
on the acrosome of sperm. Normally, capacitation is initiated through the loss of DF before the spermatozoa can perform the acrosomal reaction. Physiologically
Decapacitation_factor
Family of transport proteins
morphology, which is indicative of normal progression of spermatogenesis. Acrosome reaction Qi H, Moran MM, Navarro B, Chong JA, Krapivinsky G, Krapivinsky L
Cation_channels_of_sperm
American Biologist (1910–1978)
process of fertilization in invertebrates. Both of Jean’s Studies on the Acrosome (the second being published in 1954) pioneered the use of the electron
Jean_Clark_Dan
Structure surrounding the surface of the plasma membrane of an ovum
selective nutrients between the albumen and the yolk. Teleost fish have no acrosome on their sperm cells. Their eggs coats have a small opening that lets a
Vitelline_membrane
acetylcholine – acetyl-CoA – acid – acid precipitation – acoelomate – acrosome – actin – action potential – active site – adaptive radiation – address-message
Index_of_biology_articles
Class of enzymes
[citation needed] In mammalian fertilization, hyaluronidase is released by the acrosome of the sperm cell after it has reached the oocyte, by digesting hyaluronan
Hyaluronidase
Development and formation of the human embryo
the third process of acrosomal reaction takes place; the front part of the spermatozoan head is capped by an acrosome which contains digestive enzymes
Human_embryonic_development
Breakdown of proteins into smaller polypeptides or amino acids
function in sperm adhesion to the zona pellucida during exocytosis of the acrosome". Biochemical Journal. 375 (Pt 2): 477–488. doi:10.1042/BJ20030753. ISSN 0264-6021
Proteolysis
Specialized subunit within a cell
photosynthetic structures. Purple bacteria have "chromatophores", which are reaction centers found in invaginations of the cell membrane. Green sulfur bacteria
Organelle
further analysis. Datasets from physical systems. OpenReACT-CHON-EFH (Open Reaction Dataset of Atomic ConfiguraTions comprising C, H, O and N with Energies
List of datasets for machine-learning research
List_of_datasets_for_machine-learning_research
Enclosing or separating membrane in organisms acting as selective semi-permeable barrier
COPII-coated vesicles) and secretory vesicles (including synaptosome, acrosomes, melanosomes, and chromaffin granules). Different types of biological
Biological_membrane
Process for assessing human fertility
content, oxidative stress, maturation assessment, DNA fragmentation and acrosome activity. Checks are also made to identify undescended testicles and retrograde
Fertility_testing
Family of transport protein complexes
tumor metastasis. V-ATPases in the acrosomal membrane of sperm acidify the acrosome. This acidification activates proteases required to drill through the plasma
V-ATPase
ACROSOME REACTION
ACROSOME REACTION
Boy/Male
Hindu, Indian, Tamil
New Taste; Nine Types of Reactions
Surname or Lastname
English
English : nickname for a cripple or hunchback, from Middle English crom(p), Old English crumb ‘bent’, ‘crooked’, ‘stooping’. Compare Crump.English : metonymic occupational name for a maker, seller, or user of hooks, from Middle English crome, cromb ‘hook’, ‘crook’ (from Old English crumb ‘bent’, reinforced by an Old French borrowing from a Germanic cognate).English : habitational name from Croom in East Yorkshire or Croome in Worcestershire. The first is named with Old English crÅhum, dative plural (used originally after a preposition) of crÅh ‘narrow valley’ (a cognate of Old Norse krá ‘corner’, ‘bend’, and related to the words mentioned in 1 and 2 above). The place in Worcestershire is named with an old British river name ultimately cognate with the other words mentioned here; compare Welsh crwm ‘crooked’, ‘winding’.Americanized spelling of German Krumm.
ACROSOME REACTION
ACROSOME REACTION
ACROSOME REACTION
ACROSOME REACTION
ACROSOME REACTION
ACROSOME REACTION
ACROSOME REACTION
n.
The abdomen, or post-abdomen, of arthropods.
n.
A water wheel, commonly horizontal, variously constructed, but usually having a series of curved floats or buckets, against which the water acts by its impulse or reaction in flowing either outward from a central chamber, inward from an external casing, or from above downward, etc.; -- also called turbine wheel.
n.
A reaction employed to recognize or distinguish any particular substance or constituent of a compound, as the production of some characteristic precipitate; also, the reagent employed to produce such reaction; thus, the ordinary test for sulphuric acid is the production of a white insoluble precipitate of barium sulphate by means of some soluble barium salt.
pl.
of Reactionary
n.
A reactionary.
n.
A spore borne at the extremity of the cells of fructification in fungi.
n.
A dome parallel to the longer lateral axis of an orthorhombic crystal. See Dome, n., 4.
n.
The mutual or reciprocal action of chemical agents upon each other, or the action upon such chemical agents of some form of energy, as heat, light, or electricity, resulting in a chemical change in one or more of these agents, with the production of new compounds or the manifestation of distinctive characters. See Blowpipe reaction, Flame reaction, under Blowpipe, and Flame.
n.
Aerated salt; a white crystalline substance having an alkaline taste and reaction, consisting of sodium bicarbonate (see under Sodium.) It is largely used in cooking, with sour milk (lactic acid) or cream of tartar as a substitute for yeast. It is also an ingredient of most baking powders, and is used in the preparation of effervescing drinks.
n.
One of the serial segments, or metameres, of which the bodies of vertebrate and articulate animals are composed.
n.
A firework which, while burning, is caused to revolve on an axis by the reaction of the escaping gases.
n.
One who favors reaction, or seeks to undo political progress or revolution.
n.
A radioactive isotope of strontium produced by certain nuclear reactions, and constituting one of the prominent harmful components of radioactive fallout from nuclear explosions; also called radiostrontium. It has a half-life of 28 years.
n.
The art or process of making a compound by putting the ingredients together, as contrasted with analysis; thus, water is made by synthesis from hydrogen and oxygen; hence, specifically, the building up of complex compounds by special reactions, whereby their component radicals are so grouped that the resulting substances are identical in every respect with the natural articles when such occur; thus, artificial alcohol, urea, indigo blue, alizarin, etc., are made by synthesis.
a.
Being, causing, or favoring reaction; as, reactionary movements.
n.
Any compound ascidian of the genus Pyrosoma. The pyrosomes form large hollow cylinders, sometimes two or three feet long, which swim at the surface of the sea and are very phosphorescent.
n.
Simple succession, or the coming after in time, without asserting or implying causative energy; as, the reactions of chemical agents may be conceived as merely invariable sequences.
a.
Pertaining to, or derived from, xanthoprotein; showing the characters of xanthoprotein; as, xanthoproteic acid; the xanthoproteic reaction for albumin.