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Protein-coding gene in the species Homo sapiens
necessary step in allowing sperm to fertilize an egg. It is encoded by the ABHD2 gene. This gene encodes a protein containing an alpha/beta hydrolase fold
ABHD2
HGNC:13886; Q9H222 75 ABCG8 HGNC:13887; Q9H221 76 ABHD1 HGNC:17553; Q96SE0 77 ABHD2 HGNC:18717; P08910 78 ABHD3 HGNC:18718; Q8WU67 79 ABHD4 HGNC:20154 80 ABHD5
List of human protein-coding genes 1
List_of_human_protein-coding_genes_1
Family of transport proteins
oocyte. Progesterone binds to the protein ABHD2 which is present in the sperm plasma membrane, which causes ABHD2 to cleave an inhibitor of CatSper
Cation_channels_of_sperm
Chemical compound
amide hydrolase (FAAH), and the uncharacterized serine hydrolase enzymes ABHD2, ABHD6 and ABHD12. The exact contribution of each of these enzymes to the
2-Arachidonoylglycerol
Protein family
superfamily of proteins. 3-oxoadipate enol-lactonase InterPro: IPR012790 ABHD2; ABHD3; ABHD4; ABHD5; ABHD6; ABHD7; ABHD8; ABHD9; ABHD10; ABHD11; ABHD12;
Alpha/beta hydrolase superfamily
Alpha/beta_hydrolase_superfamily
Cellular and developmental biologist (born 1974)
mechanism for how progesterone activates spermatozoa through the protein ABHD2. In 2022 she was awarded the Senior Cranefield Award by The Journal of General
Polina_V._Lishko
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