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YBX2

  • YBX2

    • Protein-coding gene in the species Homo sapiens

    Y-box-binding protein 2 is a protein that in humans is encoded by the YBX2 gene. The YBX2 protein is a transcription factor that is expressed in sperm and

    YBX2

    YBX2

    YBX2

  • Ytterbium

    • Chemical element with atomic number 70 (Yb)

    disproportionate to the trihalides and metallic ytterbium at high temperature: 3 YbX2 → 2 YbX3 + Yb (X = F, Cl, Br, I) Some ytterbium halides are used as reagents

    Ytterbium

    Ytterbium

    Ytterbium

  • Chromosome 17

    • Human chromosome

    WFDC21P: encoding protein WAP four-disulfide core domain 21, pseudogene YBX2: encoding protein Y-box-binding protein 2 ZNF207: encoding protein Zinc finger

    Chromosome 17

    Chromosome 17

    Chromosome_17

  • NF-κB

    • Family of transcription factor protein complexes

    4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3 RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other

    NF-κB

    NF-κB

    NF-κB

  • NFE2L2

    • Human protein and coding gene

    4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3 RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other

    NFE2L2

    NFE2L2

    NFE2L2

  • TAF2

    • Protein-coding gene in the species Homo sapiens

    4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3 RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other

    TAF2

    TAF2

    TAF2

  • ASCL1

    • Protein-coding gene in humans

    4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3 RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other

    ASCL1

    ASCL1

    ASCL1

  • P53

    • Mammalian protein found in humans

    4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3 RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other

    P53

    P53

    P53

  • Receptor (biochemistry)

    • Protein molecule receiving signals for a cell

    4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3 RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other

    Receptor (biochemistry)

    Receptor (biochemistry)

    Receptor_(biochemistry)

  • Myc

    • Family of regulator genes

    4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3 RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other

    Myc

    Myc

  • Sex-determining region Y protein

    • Protein that initiates male sex determination in therian mammals

    4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3 RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other

    Sex-determining region Y protein

    Sex-determining region Y protein

    Sex-determining_region_Y_protein

  • PAX6

    • Protein-coding gene in humans

    4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3 RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other

    PAX6

    PAX6

    PAX6

  • Ytterbium compounds

    • disproportionate to the trihalides and metallic ytterbium at high temperature: 3 YbX2 → 2 YbX3 + Yb (X = F, Cl, Br, I) Some ytterbium halides are used as reagents

    Ytterbium compounds

    Ytterbium compounds

    Ytterbium_compounds

  • Progesterone receptor

    • Cytoplasmic receptor protein found inside cells

    4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3 RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other

    Progesterone receptor

    Progesterone receptor

    Progesterone_receptor

  • CREB

    • Class of proteins

    4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3 RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other

    CREB

    CREB

    CREB

  • IRF4

    • Protein-coding gene in the species Homo sapiens

    4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3 RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other

    IRF4

    IRF4

    IRF4

  • CLOCK

    • Human protein and coding gene

    4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3 RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other

    CLOCK

    CLOCK

    CLOCK

  • Peroxisome proliferator-activated receptor

    • Group of nuclear receptor proteins

    4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3 RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other

    Peroxisome proliferator-activated receptor

    Peroxisome proliferator-activated receptor

    Peroxisome_proliferator-activated_receptor

  • Homeobox

    • DNA pattern affecting anatomy development

    4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3 RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other

    Homeobox

    Homeobox

    Homeobox

  • KMT2A

    • Protein-coding gene in the species Homo sapiens

    4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3 RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other

    KMT2A

    KMT2A

    KMT2A

  • List of human transcription factors

    • ENSG00000065978 CSD Known motif – High-throughput in vitro [1,010] YGTWCCAYC YBX2 ENSG00000006047 CSD Inferred motif from similar protein – High-throughput

    List of human transcription factors

    List_of_human_transcription_factors

  • Androgen receptor

    • Mammalian protein found in humans

    4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3 RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other

    Androgen receptor

    Androgen receptor

    Androgen_receptor

  • Hepatocyte nuclear factors

    • Transcription factors

    4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3 RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other

    Hepatocyte nuclear factors

    Hepatocyte_nuclear_factors

  • SOX9

    • Transcription factor gene of the SOX family

    4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3 RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other

    SOX9

    SOX9

    SOX9

  • C7.GAT protein

    • Zinc finger protein

    4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3 RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other

    C7.GAT protein

    C7.GAT_protein

  • FOXO3

    • Protein-coding gene in humans

    4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3 RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other

    FOXO3

    FOXO3

    FOXO3

  • FOXP3

    • Immune response protein

    4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3 RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other

    FOXP3

    FOXP3

    FOXP3

  • Transcription factor

    • Protein that regulates the rate of DNA transcription

    4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3 RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other

    Transcription factor

    Transcription factor

    Transcription_factor

  • Peroxisome proliferator-activated receptor alpha

    • Nuclear receptor protein found in humans

    4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3 RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other

    Peroxisome proliferator-activated receptor alpha

    Peroxisome proliferator-activated receptor alpha

    Peroxisome_proliferator-activated_receptor_alpha

  • EPAS1

    • Protein found in humans

    4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3 RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other

    EPAS1

    EPAS1

    EPAS1

  • Vitamin D receptor

    • Transcription factor activated by vitamin D

    4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3 RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other

    Vitamin D receptor

    Vitamin D receptor

    Vitamin_D_receptor

  • AP-1 transcription factor

    • Instance of defined set in Homo sapiens with Reactome ID (R-HSA-6806560)

    4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3 RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other

    AP-1 transcription factor

    AP-1 transcription factor

    AP-1_transcription_factor

  • Estrogen receptor

    • Proteins activated by the hormone estrogen

    4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3 RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other

    Estrogen receptor

    Estrogen receptor

    Estrogen_receptor

  • Retinoic acid receptor

    • Type of nuclear receptor

    4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3 RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other

    Retinoic acid receptor

    Retinoic acid receptor

    Retinoic_acid_receptor

  • T-box transcription factor T

    • Protein-coding gene in the species Homo sapiens

    4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3 RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other

    T-box transcription factor T

    T-box transcription factor T

    T-box_transcription_factor_T

  • Zinc finger

    • Small structural protein motif found mostly in transcriptional proteins

    4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3 RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other

    Zinc finger

    Zinc finger

    Zinc_finger

  • Glucocorticoid receptor

    • Receptor to which cortisol and other glucocorticoids bind

    4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3 RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other

    Glucocorticoid receptor

    Glucocorticoid receptor

    Glucocorticoid_receptor

  • Nuclear receptor 4A2

    • Protein-coding gene in the species Homo sapiens

    4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3 RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other

    Nuclear receptor 4A2

    Nuclear receptor 4A2

    Nuclear_receptor_4A2

  • SMAD (protein)

    • Family of proteins

    4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3 RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other

    SMAD (protein)

    SMAD_(protein)

  • Hypoxia-inducible factor

    • Protein that responds to low oxygen

    4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3 RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other

    Hypoxia-inducible factor

    Hypoxia-inducible_factor

  • Leucine zipper

    • DNA-binding structural motif

    4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3 RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other

    Leucine zipper

    Leucine zipper

    Leucine_zipper

  • Thyroid hormone receptor

    • Nuclear protein

    4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3 RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other

    Thyroid hormone receptor

    Thyroid_hormone_receptor

  • Protein c-Fos

    • Mammalian protein found in Homo sapiens

    4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3 RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other

    Protein c-Fos

    Protein c-Fos

    Protein_c-Fos

  • Sterol regulatory element-binding protein 1

    • Protein-coding gene in the species Homo sapiens

    4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3 RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other

    Sterol regulatory element-binding protein 1

    Sterol regulatory element-binding protein 1

    Sterol_regulatory_element-binding_protein_1

  • Anti-sigma factors

    • Antagonists of a youth's slang

    4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3 RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other

    Anti-sigma factors

    Anti-sigma_factors

  • Zbtb7

    • Mammalian protein found in Homo sapiens

    4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3 RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other

    Zbtb7

    Zbtb7

  • Retinoid X receptor

    • Genes on human chromosome 9

    4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3 RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other

    Retinoid X receptor

    Retinoid_X_receptor

  • FOXP2

    • Transcription factor gene of the forkhead box family

    4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3 RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other

    FOXP2

    FOXP2

    FOXP2

  • SOX10

    • Transcription factor gene of the SOX family

    4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3 RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other

    SOX10

    SOX10

    SOX10

  • DPF2

    • Protein-coding gene in the species Homo sapiens

    4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3 RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other

    DPF2

    DPF2

    DPF2

  • Heterochromatin protein 1

    • Protein family

    4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3 RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other

    Heterochromatin protein 1

    Heterochromatin_protein_1

  • Steroid hormone receptor

    • Group of protein families

    4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3 RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other

    Steroid hormone receptor

    Steroid_hormone_receptor

  • ISL1

    • Protein-coding gene in the species Homo sapiens

    4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3 RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other

    ISL1

    ISL1

    ISL1

  • GATA transcription factor

    • Transcription factor

    4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3 RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other

    GATA transcription factor

    GATA transcription factor

    GATA_transcription_factor

  • General transcription factor

    • Class of protein transcription factors

    4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3 RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other

    General transcription factor

    General transcription factor

    General_transcription_factor

  • MADS-box

    • Protein family

    4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3 RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other

    MADS-box

    MADS-box

  • MNX1

    • Protein-coding gene in the species Homo sapiens

    4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3 RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other

    MNX1

    MNX1

    MNX1

  • T-box

    • Genes that affect limb and heart development

    4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3 RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other

    T-box

    T-box

    T-box

  • ETS transcription factor family

    • Protein family

    4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3 RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other

    ETS transcription factor family

    ETS transcription factor family

    ETS_transcription_factor_family

  • Catabolite activator protein

    • Trans-acting transcriptional activator

    4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3 RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other

    Catabolite activator protein

    Catabolite activator protein

    Catabolite_activator_protein

  • SOX gene family

    • Family of transcription factors

    4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3 RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other

    SOX gene family

    SOX_gene_family

  • BZIP domain

    • Protein domain

    4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3 RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other

    BZIP domain

    BZIP domain

    BZIP_domain

  • SPI1

    • Protein-coding gene in the species Homo sapiens

    4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3 RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other

    SPI1

    SPI1

    SPI1

  • Pregnane X receptor

    • Mammalian protein found in Homo sapiens

    4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3 RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other

    Pregnane X receptor

    Pregnane X receptor

    Pregnane_X_receptor

  • PROX1

    • Protein-coding gene in the species Homo sapiens

    4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3 RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other

    PROX1

    PROX1

    PROX1

  • Winged-helix transcription factors

    • Family of proteins

    4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3 RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other

    Winged-helix transcription factors

    Winged-helix transcription factors

    Winged-helix_transcription_factors

  • Peroxisome proliferator-activated receptor gamma

    • Nuclear receptor protein found in humans

    4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3 RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other

    Peroxisome proliferator-activated receptor gamma

    Peroxisome proliferator-activated receptor gamma

    Peroxisome_proliferator-activated_receptor_gamma

  • Mineralocorticoid receptor

    • Nuclear receptor that mediates the effects of the mineralocorticoid hormone Aldosterone

    4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3 RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other

    Mineralocorticoid receptor

    Mineralocorticoid receptor

    Mineralocorticoid_receptor

  • FOXH1

    • Protein-coding gene in the species Homo sapiens

    4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3 RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other

    FOXH1

    FOXH1

    FOXH1

  • PHOX2A

    • Protein-coding gene in humans

    4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3 RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other

    PHOX2A

    PHOX2A

    PHOX2A

  • MAFB (gene)

    • Protein-coding gene in the species Homo sapiens

    4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3 RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other

    MAFB (gene)

    MAFB (gene)

    MAFB_(gene)

  • High-mobility group

    • Group of proteins

    4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3 RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other

    High-mobility group

    High-mobility_group

  • Estrogen-related receptor beta

    • Protein-coding gene in the species Homo sapiens

    4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3 RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other

    Estrogen-related receptor beta

    Estrogen-related receptor beta

    Estrogen-related_receptor_beta

  • TCF3

    • Protein-coding gene in the species Homo sapiens

    4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3 RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other

    TCF3

    TCF3

    TCF3

  • ATF6

    • Protein-coding gene in the species Homo sapiens

    4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3 RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other

    ATF6

    ATF6

    ATF6

  • TEAD3

    • Protein-coding gene in the species Homo sapiens

    4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3 RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other

    TEAD3

    TEAD3

    TEAD3

  • NFIC (gene)

    • Protein-coding gene in the species Homo sapiens

    4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3 RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other

    NFIC (gene)

    NFIC (gene)

    NFIC_(gene)

  • Liver X receptor alpha

    • Nuclear receptor protein found in humans

    4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3 RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other

    Liver X receptor alpha

    Liver X receptor alpha

    Liver_X_receptor_alpha

  • KMT2B

    • Protein-coding gene in the species Homo sapiens

    4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3 RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other

    KMT2B

    KMT2B

    KMT2B

  • LHX3

    • Protein-coding gene in the species Homo sapiens

    4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3 RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other

    LHX3

    LHX3

    LHX3

  • Nuclear receptor

    • Protein

    4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3 RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other

    Nuclear receptor

    Nuclear receptor

    Nuclear_receptor

  • E2F

    • Family of transcription factors

    4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3 RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other

    E2F

    E2F

  • CCAAT-enhancer-binding proteins

    • Protein family

    4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3 RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other

    CCAAT-enhancer-binding proteins

    CCAAT-enhancer-binding proteins

    CCAAT-enhancer-binding_proteins

  • PRDM16

    • Protein-coding gene in the species Homo sapiens

    4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3 RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other

    PRDM16

    PRDM16

    PRDM16

  • Basic helix–loop–helix

    • Protein structural motif

    4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3 RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other

    Basic helix–loop–helix

    Basic helix–loop–helix

    Basic_helix–loop–helix

  • EBF1

    • Protein-coding gene in the species Homo sapiens

    4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3 RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other

    EBF1

    EBF1

    EBF1

  • TCF4

    • Protein-coding gene in the species Homo sapiens

    4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3 RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other

    TCF4

    TCF4

    TCF4

  • DMRT1

    • Protein-coding gene in humans

    4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3 RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other

    DMRT1

    DMRT1

    DMRT1

  • Transcription factor II A

    • Nuclear protein

    4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3 RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other

    Transcription factor II A

    Transcription_factor_II_A

  • Pax genes

    • Family of transcription factors

    4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3 RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other

    Pax genes

    Pax genes

    Pax_genes

  • Transcription factor II H

    • Protein complex

    4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3 RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other

    Transcription factor II H

    Transcription_factor_II_H

  • Rho factor

    • Prokaryotic protein

    4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3 RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other

    Rho factor

    Rho factor

    Rho_factor

  • RUNX1T1

    • Protein-coding gene in humans

    4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3 RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other

    RUNX1T1

    RUNX1T1

    RUNX1T1

  • Retinoic acid receptor gamma

    • Protein-coding gene in the species Homo sapiens

    4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3 RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other

    Retinoic acid receptor gamma

    Retinoic acid receptor gamma

    Retinoic_acid_receptor_gamma

  • TRPS1

    • Protein-coding gene in the species Homo sapiens

    4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3 RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other

    TRPS1

    TRPS1

    TRPS1

  • STAT protein

    • Family of intracellular transcription factors

    4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3 RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other

    STAT protein

    STAT protein

    STAT_protein

  • Helix-turn-helix

    • Structural motif capable of binding DNA

    4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3 RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other

    Helix-turn-helix

    Helix-turn-helix

    Helix-turn-helix

  • ParaHox

    • Gene cluster

    4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3 RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other

    ParaHox

    ParaHox

  • Pocket protein family

    • Protein family

    4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3 RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other

    Pocket protein family

    Pocket_protein_family

  • MTA3

    • Protein-coding gene in the species Homo sapiens

    4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3 RUNX1 RUNX2 RUNX3 RUNX1T1 (0) Other

    MTA3

    MTA3

    MTA3

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