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TFCP2

  • TFCP2

    • Protein-coding gene in the species Homo sapiens

    transcription factor CP2 is a protein that in humans is encoded by the TFCP2 gene. TFCP2 is also called Late SV40 factor (LSF) and it is induced by well-known

    TFCP2

    TFCP2

    TFCP2

  • Ulla Hansen

    • American biologist

    research group focuses on the study of transcription factor LSF (also known as TFCP2). Hansen received her bachelor's degree in 1974 from Oberlin College and

    Ulla Hansen

    Ulla_Hansen

  • FET protein family

    • Family of RNA-binding proteins

    that by definition contain neoplastic cells that express the EWSR1-TFCP2 or FUS-TFCP2 fusion gene. Simple bone cyst (also termed unicameral bone cysts):

    FET protein family

    FET_protein_family

  • BARX homeobox 1

    • Human protein

    17 18 21 SRY SSRP1 TCF/LEF TCF 1 3 4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3

    BARX homeobox 1

    BARX homeobox 1

    BARX_homeobox_1

  • NF-κB

    • Family of transcription factor protein complexes

    17 18 21 SRY SSRP1 TCF/LEF TCF 1 3 4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3

    NF-κB

    NF-κB

    NF-κB

  • Sex-determining region Y protein

    • Protein that initiates male sex determination in therian mammals

    17 18 21 SRY SSRP1 TCF/LEF TCF 1 3 4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3

    Sex-determining region Y protein

    Sex-determining region Y protein

    Sex-determining_region_Y_protein

  • NKX 2-9

    • Transcription factor

    17 18 21 SRY SSRP1 TCF/LEF TCF 1 3 4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3

    NKX 2-9

    NKX_2-9

  • P53

    • Mammalian protein found in humans

    17 18 21 SRY SSRP1 TCF/LEF TCF 1 3 4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3

    P53

    P53

    P53

  • MTDH

    • Protein-coding gene in the species Homo sapiens

    factor (LSF/TFCP2) which is involved in thymidylate synthase (TS) induction and DNA biosynthesis synthesis. Late SV40 factor (LSF/TFCP2) enhances angiogenesis

    MTDH

    MTDH

    MTDH

  • GSX2

    • 17 18 21 SRY SSRP1 TCF/LEF TCF 1 3 4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3

    GSX2

    GSX2

    GSX2

  • Progesterone receptor

    • Cytoplasmic receptor protein found inside cells

    17 18 21 SRY SSRP1 TCF/LEF TCF 1 3 4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3

    Progesterone receptor

    Progesterone receptor

    Progesterone_receptor

  • IRF4

    • Protein-coding gene in the species Homo sapiens

    17 18 21 SRY SSRP1 TCF/LEF TCF 1 3 4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3

    IRF4

    IRF4

    IRF4

  • Receptor (biochemistry)

    • Protein molecule receiving signals for a cell

    17 18 21 SRY SSRP1 TCF/LEF TCF 1 3 4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3

    Receptor (biochemistry)

    Receptor (biochemistry)

    Receptor_(biochemistry)

  • List of human transcription factors

    • ENSG00000090447 bHLH Known motif – High-throughput in vitro [940] VWCAGCTGWB TFCP2 ENSG00000135457 Grainyhead Known motif – High-throughput in vitro [941]

    List of human transcription factors

    List_of_human_transcription_factors

  • Homeobox

    • DNA pattern affecting anatomy development

    17 18 21 SRY SSRP1 TCF/LEF TCF 1 3 4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3

    Homeobox

    Homeobox

    Homeobox

  • ASCL1

    • Protein-coding gene in humans

    17 18 21 SRY SSRP1 TCF/LEF TCF 1 3 4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3

    ASCL1

    ASCL1

    ASCL1

  • Thymidylate synthase

    • Enzyme

    vertebrates. Thymidylate synthase is induced by a transcription factor LSF/TFCP2 and LSF is an oncogene in hepatocellular carcinoma. LSF and Thymidylate

    Thymidylate synthase

    Thymidylate synthase

    Thymidylate_synthase

  • SOX9

    • Transcription factor gene of the SOX family

    17 18 21 SRY SSRP1 TCF/LEF TCF 1 3 4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3

    SOX9

    SOX9

    SOX9

  • CREB

    • Class of proteins

    17 18 21 SRY SSRP1 TCF/LEF TCF 1 3 4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3

    CREB

    CREB

    CREB

  • FOX proteins

    • Family of transcription factors involved in anatomical development

    17 18 21 SRY SSRP1 TCF/LEF TCF 1 3 4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3

    FOX proteins

    FOX proteins

    FOX_proteins

  • FOXO3

    • Protein-coding gene in humans

    17 18 21 SRY SSRP1 TCF/LEF TCF 1 3 4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3

    FOXO3

    FOXO3

    FOXO3

  • PAX6

    • Protein-coding gene in humans

    17 18 21 SRY SSRP1 TCF/LEF TCF 1 3 4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3

    PAX6

    PAX6

    PAX6

  • E2F

    • Family of transcription factors

    17 18 21 SRY SSRP1 TCF/LEF TCF 1 3 4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3

    E2F

    E2F

  • Transcription factor

    • Protein that regulates the rate of DNA transcription

    17 18 21 SRY SSRP1 TCF/LEF TCF 1 3 4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3

    Transcription factor

    Transcription factor

    Transcription_factor

  • EPAS1

    • Protein found in humans

    17 18 21 SRY SSRP1 TCF/LEF TCF 1 3 4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3

    EPAS1

    EPAS1

    EPAS1

  • AP-1 transcription factor

    • Instance of defined set in Homo sapiens with Reactome ID (R-HSA-6806560)

    17 18 21 SRY SSRP1 TCF/LEF TCF 1 3 4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain CSDA YBX1 (4.11) Runt CBF CBFA2T2 CBFA2T3 RUNX1

    AP-1 transcription factor

    AP-1 transcription factor

    AP-1_transcription_factor

  • Vitamin D receptor

    • Transcription factor activated by vitamin D

    17 18 21 SRY SSRP1 TCF/LEF TCF 1 3 4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3

    Vitamin D receptor

    Vitamin D receptor

    Vitamin_D_receptor

  • T-box transcription factor T

    • Protein-coding gene in the species Homo sapiens

    17 18 21 SRY SSRP1 TCF/LEF TCF 1 3 4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3

    T-box transcription factor T

    T-box transcription factor T

    T-box_transcription_factor_T

  • Myc

    • Family of regulator genes

    17 18 21 SRY SSRP1 TCF/LEF TCF 1 3 4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3

    Myc

    Myc

  • Zinc finger

    • Small structural protein motif found mostly in transcriptional proteins

    17 18 21 SRY SSRP1 TCF/LEF TCF 1 3 4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3

    Zinc finger

    Zinc finger

    Zinc_finger

  • Peroxisome proliferator-activated receptor alpha

    • Nuclear receptor protein found in humans

    17 18 21 SRY SSRP1 TCF/LEF TCF 1 3 4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3

    Peroxisome proliferator-activated receptor alpha

    Peroxisome proliferator-activated receptor alpha

    Peroxisome_proliferator-activated_receptor_alpha

  • NFE2L2

    • Human protein and coding gene

    17 18 21 SRY SSRP1 TCF/LEF TCF 1 3 4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3

    NFE2L2

    NFE2L2

    NFE2L2

  • FOSB

    • Protein

    17 18 21 SRY SSRP1 TCF/LEF TCF 1 3 4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3

    FOSB

    FOSB

    FOSB

  • SMAD (protein)

    • Family of proteins

    17 18 21 SRY SSRP1 TCF/LEF TCF 1 3 4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3

    SMAD (protein)

    SMAD_(protein)

  • Hypoxia-inducible factor

    • Protein that responds to low oxygen

    17 18 21 SRY SSRP1 TCF/LEF TCF 1 3 4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3

    Hypoxia-inducible factor

    Hypoxia-inducible_factor

  • Peroxisome proliferator-activated receptor gamma

    • Nuclear receptor protein found in humans

    17 18 21 SRY SSRP1 TCF/LEF TCF 1 3 4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3

    Peroxisome proliferator-activated receptor gamma

    Peroxisome proliferator-activated receptor gamma

    Peroxisome_proliferator-activated_receptor_gamma

  • Nuclear receptor

    • Protein

    17 18 21 SRY SSRP1 TCF/LEF TCF 1 3 4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3

    Nuclear receptor

    Nuclear receptor

    Nuclear_receptor

  • Estrogen receptor

    • Proteins activated by the hormone estrogen

    17 18 21 SRY SSRP1 TCF/LEF TCF 1 3 4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3

    Estrogen receptor

    Estrogen receptor

    Estrogen_receptor

  • Transcription factor Sp1

    • Protein-coding gene in the species Homo sapiens

    17 18 21 SRY SSRP1 TCF/LEF TCF 1 3 4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3

    Transcription factor Sp1

    Transcription factor Sp1

    Transcription_factor_Sp1

  • Autoimmune regulator

    • Immune system protein

    17 18 21 SRY SSRP1 TCF/LEF TCF 1 3 4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3

    Autoimmune regulator

    Autoimmune regulator

    Autoimmune_regulator

  • TATA-binding protein

    • Protein-coding gene in the species Homo sapiens

    17 18 21 SRY SSRP1 TCF/LEF TCF 1 3 4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3

    TATA-binding protein

    TATA-binding protein

    TATA-binding_protein

  • FOXP2

    • Transcription factor gene of the forkhead box family

    17 18 21 SRY SSRP1 TCF/LEF TCF 1 3 4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3

    FOXP2

    FOXP2

    FOXP2

  • Zbtb7

    • Mammalian protein found in Homo sapiens

    17 18 21 SRY SSRP1 TCF/LEF TCF 1 3 4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3

    Zbtb7

    Zbtb7

  • Retinoblastoma protein

    • Mammalian protein found in humans

    17 18 21 SRY SSRP1 TCF/LEF TCF 1 3 4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3

    Retinoblastoma protein

    Retinoblastoma protein

    Retinoblastoma_protein

  • Retinoic acid receptor

    • Type of nuclear receptor

    17 18 21 SRY SSRP1 TCF/LEF TCF 1 3 4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3

    Retinoic acid receptor

    Retinoic acid receptor

    Retinoic_acid_receptor

  • Zinc finger inhibitor

    • 17 18 21 SRY SSRP1 TCF/LEF TCF 1 3 4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3

    Zinc finger inhibitor

    Zinc finger inhibitor

    Zinc_finger_inhibitor

  • FOXP3

    • Immune response protein

    17 18 21 SRY SSRP1 TCF/LEF TCF 1 3 4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3

    FOXP3

    FOXP3

    FOXP3

  • PROX1

    • Protein-coding gene in the species Homo sapiens

    17 18 21 SRY SSRP1 TCF/LEF TCF 1 3 4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3

    PROX1

    PROX1

    PROX1

  • Pregnane X receptor

    • Mammalian protein found in Homo sapiens

    17 18 21 SRY SSRP1 TCF/LEF TCF 1 3 4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3

    Pregnane X receptor

    Pregnane X receptor

    Pregnane_X_receptor

  • Steroid hormone receptor

    • Group of protein families

    17 18 21 SRY SSRP1 TCF/LEF TCF 1 3 4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3

    Steroid hormone receptor

    Steroid_hormone_receptor

  • Retinoic acid receptor alpha

    • Protein found in humans

    17 18 21 SRY SSRP1 TCF/LEF TCF 1 3 4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3

    Retinoic acid receptor alpha

    Retinoic acid receptor alpha

    Retinoic_acid_receptor_alpha

  • Androgen receptor

    • Mammalian protein found in humans

    17 18 21 SRY SSRP1 TCF/LEF TCF 1 3 4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3

    Androgen receptor

    Androgen receptor

    Androgen_receptor

  • GATA3

    • Protein-coding gene in the species Homo sapiens

    17 18 21 SRY SSRP1 TCF/LEF TCF 1 3 4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3

    GATA3

    GATA3

    GATA3

  • TCF4

    • Protein-coding gene in the species Homo sapiens

    17 18 21 SRY SSRP1 TCF/LEF TCF 1 3 4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3

    TCF4

    TCF4

    TCF4

  • Microphthalmia-associated transcription factor

    • Mammalian protein found in humans

    17 18 21 SRY SSRP1 TCF/LEF TCF 1 3 4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3

    Microphthalmia-associated transcription factor

    Microphthalmia-associated transcription factor

    Microphthalmia-associated_transcription_factor

  • KMT2B

    • Protein-coding gene in the species Homo sapiens

    17 18 21 SRY SSRP1 TCF/LEF TCF 1 3 4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3

    KMT2B

    KMT2B

    KMT2B

  • LHX3

    • Protein-coding gene in the species Homo sapiens

    17 18 21 SRY SSRP1 TCF/LEF TCF 1 3 4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3

    LHX3

    LHX3

    LHX3

  • DMRT1

    • Protein-coding gene in humans

    17 18 21 SRY SSRP1 TCF/LEF TCF 1 3 4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3

    DMRT1

    DMRT1

    DMRT1

  • KMT2A

    • Protein-coding gene in the species Homo sapiens

    17 18 21 SRY SSRP1 TCF/LEF TCF 1 3 4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3

    KMT2A

    KMT2A

    KMT2A

  • Catabolite activator protein

    • Trans-acting transcriptional activator

    17 18 21 SRY SSRP1 TCF/LEF TCF 1 3 4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3

    Catabolite activator protein

    Catabolite activator protein

    Catabolite_activator_protein

  • BZIP domain

    • Protein domain

    17 18 21 SRY SSRP1 TCF/LEF TCF 1 3 4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3

    BZIP domain

    BZIP domain

    BZIP_domain

  • SOX gene family

    • Family of transcription factors

    17 18 21 SRY SSRP1 TCF/LEF TCF 1 3 4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3

    SOX gene family

    SOX_gene_family

  • Winged-helix transcription factors

    • Family of proteins

    17 18 21 SRY SSRP1 TCF/LEF TCF 1 3 4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3

    Winged-helix transcription factors

    Winged-helix transcription factors

    Winged-helix_transcription_factors

  • Estrogen receptor beta

    • Protein-coding gene in the species Homo sapiens

    17 18 21 SRY SSRP1 TCF/LEF TCF 1 3 4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3

    Estrogen receptor beta

    Estrogen receptor beta

    Estrogen_receptor_beta

  • TRPS1

    • Protein-coding gene in the species Homo sapiens

    17 18 21 SRY SSRP1 TCF/LEF TCF 1 3 4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3

    TRPS1

    TRPS1

    TRPS1

  • NFIL3

    • Protein-coding gene in the species Homo sapiens

    17 18 21 SRY SSRP1 TCF/LEF TCF 1 3 4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3

    NFIL3

    NFIL3

    NFIL3

  • List of human protein-coding genes 8

    • Q01664 16592 TFB1M HGNC:17037; Q8WVM0 16593 TFB2M HGNC:18559; Q9H5Q4 16594 TFCP2 HGNC:11748; Q12800 16595 TFCP2L1 HGNC:17925; Q9NZI6 16596 TFDP1 HGNC:11749;

    List of human protein-coding genes 8

    List_of_human_protein-coding_genes_8

  • Helix-turn-helix

    • Structural motif capable of binding DNA

    17 18 21 SRY SSRP1 TCF/LEF TCF 1 3 4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3

    Helix-turn-helix

    Helix-turn-helix

    Helix-turn-helix

  • Retinoic acid receptor gamma

    • Protein-coding gene in the species Homo sapiens

    17 18 21 SRY SSRP1 TCF/LEF TCF 1 3 4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3

    Retinoic acid receptor gamma

    Retinoic acid receptor gamma

    Retinoic_acid_receptor_gamma

  • Estrogen receptor alpha

    • Protein-coding gene in the species Homo sapiens

    17 18 21 SRY SSRP1 TCF/LEF TCF 1 3 4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3

    Estrogen receptor alpha

    Estrogen receptor alpha

    Estrogen_receptor_alpha

  • MNX1

    • Protein-coding gene in the species Homo sapiens

    17 18 21 SRY SSRP1 TCF/LEF TCF 1 3 4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3

    MNX1

    MNX1

    MNX1

  • Rho factor

    • Prokaryotic protein

    17 18 21 SRY SSRP1 TCF/LEF TCF 1 3 4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3

    Rho factor

    Rho factor

    Rho_factor

  • EGR1

    • Protein-coding gene in the species Homo sapiens

    17 18 21 SRY SSRP1 TCF/LEF TCF 1 3 4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3

    EGR1

    EGR1

    EGR1

  • Basic helix–loop–helix

    • Protein structural motif

    17 18 21 SRY SSRP1 TCF/LEF TCF 1 3 4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain CSDA YBX1 (4.11) Runt CBF CBFA2T2 CBFA2T3 RUNX1

    Basic helix–loop–helix

    Basic helix–loop–helix

    Basic_helix–loop–helix

  • IRF3

    • Protein-coding gene in the species Homo sapiens

    17 18 21 SRY SSRP1 TCF/LEF TCF 1 3 4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3

    IRF3

    IRF3

    IRF3

  • EBF1

    • Protein-coding gene in the species Homo sapiens

    17 18 21 SRY SSRP1 TCF/LEF TCF 1 3 4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3

    EBF1

    EBF1

    EBF1

  • LBX2

    • Protein-coding gene in the species Homo sapiens

    17 18 21 SRY SSRP1 TCF/LEF TCF 1 3 4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3

    LBX2

    LBX2

    LBX2

  • BCL6

    • Transcription factor for converting Naive T cells to TFH

    17 18 21 SRY SSRP1 TCF/LEF TCF 1 3 4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3

    BCL6

    BCL6

    BCL6

  • Transcription factor II H

    • Protein complex

    17 18 21 SRY SSRP1 TCF/LEF TCF 1 3 4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3

    Transcription factor II H

    Transcription_factor_II_H

  • FOXA2

    • Mammalian protein found in Homo sapiens

    17 18 21 SRY SSRP1 TCF/LEF TCF 1 3 4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3

    FOXA2

    FOXA2

    FOXA2

  • Pax genes

    • Family of transcription factors

    17 18 21 SRY SSRP1 TCF/LEF TCF 1 3 4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3

    Pax genes

    Pax genes

    Pax_genes

  • Homeobox A10

    • Protein-coding gene in humans

    17 18 21 SRY SSRP1 TCF/LEF TCF 1 3 4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3

    Homeobox A10

    Homeobox A10

    Homeobox_A10

  • ZNF644

    • Protein-coding gene in the species Homo sapiens

    17 18 21 SRY SSRP1 TCF/LEF TCF 1 3 4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3

    ZNF644

    ZNF644

    ZNF644

  • Transcription factor II D

    • General transcription factors

    17 18 21 SRY SSRP1 TCF/LEF TCF 1 3 4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3

    Transcription factor II D

    Transcription_factor_II_D

  • Intracellular receptor

    • Receptors located inside the cell

    17 18 21 SRY SSRP1 TCF/LEF TCF 1 3 4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3

    Intracellular receptor

    Intracellular_receptor

  • RNF2

    • Protein-coding gene in the species Homo sapiens

    interact with, and suppress the activity of, transcription factor CP2 (TFCP2/CP2). Studies of the mouse counterpart suggested the involvement of this

    RNF2

    RNF2

    RNF2

  • RBPJ

    • Protein-coding gene in the species Homo sapiens

    17 18 21 SRY SSRP1 TCF/LEF TCF 1 3 4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3

    RBPJ

    RBPJ

    RBPJ

  • HOXB8

    • Protein-coding gene in the species Homo sapiens

    17 18 21 SRY SSRP1 TCF/LEF TCF 1 3 4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3

    HOXB8

    HOXB8

    HOXB8

  • FOXP1

    • Protein-coding gene in the species Homo sapiens

    17 18 21 SRY SSRP1 TCF/LEF TCF 1 3 4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3

    FOXP1

    FOXP1

    FOXP1

  • SIM2

    • Protein-coding gene in the species Homo sapiens

    17 18 21 SRY SSRP1 TCF/LEF TCF 1 3 4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3

    SIM2

    SIM2

    SIM2

  • FOSL2

    • Protein-coding gene in the species Homo sapiens

    17 18 21 SRY SSRP1 TCF/LEF TCF 1 3 4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3

    FOSL2

    FOSL2

    FOSL2

  • Basic helix-loop-helix ARNT-like protein 1

    • Human protein and coding gene

    17 18 21 SRY SSRP1 TCF/LEF TCF 1 3 4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3

    Basic helix-loop-helix ARNT-like protein 1

    Basic helix-loop-helix ARNT-like protein 1

    Basic_helix-loop-helix_ARNT-like_protein_1

  • Serum response factor

    • Mammalian protein found in Homo sapiens

    17 18 21 SRY SSRP1 TCF/LEF TCF 1 3 4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3

    Serum response factor

    Serum response factor

    Serum_response_factor

  • PHF1

    • Protein-coding gene in the species Homo sapiens

    17 18 21 SRY SSRP1 TCF/LEF TCF 1 3 4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3

    PHF1

    PHF1

    PHF1

  • SMAD5

    • Protein-coding gene in the species Homo sapiens

    17 18 21 SRY SSRP1 TCF/LEF TCF 1 3 4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3

    SMAD5

    SMAD5

    SMAD5

  • Neurogenins

    • Protein family

    17 18 21 SRY SSRP1 TCF/LEF TCF 1 3 4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3

    Neurogenins

    Neurogenins

  • Thyroid hormone receptor beta

    • Protein-coding gene in the species Homo sapiens

    17 18 21 SRY SSRP1 TCF/LEF TCF 1 3 4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3

    Thyroid hormone receptor beta

    Thyroid hormone receptor beta

    Thyroid_hormone_receptor_beta

  • PAX2

    • Protein-coding gene in humans

    17 18 21 SRY SSRP1 TCF/LEF TCF 1 3 4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3

    PAX2

    PAX2

    PAX2

  • TCF7

    • Protein-coding gene in the species Homo sapiens

    17 18 21 SRY SSRP1 TCF/LEF TCF 1 3 4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3

    TCF7

    TCF7

    TCF7

  • MEOX1

    • Protein-coding gene in the species Homo sapiens

    17 18 21 SRY SSRP1 TCF/LEF TCF 1 3 4 LEF1 TOX 1 2 3 4 (4.9) Grainyhead TFCP2 (4.10) Cold-shock domain YBX1 YBX2 YBX3 (4.11) Runt CBF CBFA2T2 CBFA2T3

    MEOX1

    MEOX1

    MEOX1

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