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TESAMORELIN

  • Tesamorelin

    • Pharmaceutical drug

    Tesamorelin (INN; trade name Egrifta SV) is a synthetic form of growth-hormone-releasing hormone (GHRH) which is used in the treatment of HIV-associated

    Tesamorelin

    Tesamorelin

    Tesamorelin

  • Growth hormone secretagogue

    • Class of drugs

    hormone-releasing hormone (GHRH, somatorelin), CJC-1295, sermorelin, and tesamorelin. Many of them also induce the secretion of insulin-like growth factor

    Growth hormone secretagogue

    Growth_hormone_secretagogue

  • Steven Grinspoon

    • American physician

    approved Tesamorelin for HIV-associated lipodystrophy in 2010. Subsequent studies, published in JAMA and Lancet HIV, demonstrated that Tesamorelin reduced

    Steven Grinspoon

    Steven Grinspoon

    Steven_Grinspoon

  • Growth hormone–releasing hormone

    • Mammalian protein found in Homo sapiens

    been used in the diagnosis of deficiencies in growth hormone secretion. Tesamorelin, under the trade name Egrifta, received U.S. Food and Drug Administration

    Growth hormone–releasing hormone

    Growth_hormone–releasing_hormone

  • Growth hormone therapy

    • Type of hormone therapy

    Dumorelin GHRH Modified GRF (1-29) Rismorelin Sermorelin Somatorelin Tesamorelin Antagonists: MZ-5-156 GHS (ghrelin) Agonists: Peptide: Alexamorelin Cortistatin-14

    Growth hormone therapy

    Growth_hormone_therapy

  • Ibutamoren

    • Experimental drug

    Dumorelin GHRH Modified GRF (1-29) Rismorelin Sermorelin Somatorelin Tesamorelin Antagonists: MZ-5-156 GHS (ghrelin) Agonists: Peptide: Alexamorelin Cortistatin-14

    Ibutamoren

    Ibutamoren

    Ibutamoren

  • CJC-1295

    • Chemical compound

    Dumorelin GHRH Modified GRF (1-29) Rismorelin Sermorelin Somatorelin Tesamorelin Antagonists: MZ-5-156 GHS (ghrelin) Agonists: Peptide: Alexamorelin Cortistatin-14

    CJC-1295

    CJC-1295

  • Ipamorelin

    • Peptide selective agonist of the ghrelin/growth hormone secretagogue receptor

    Dumorelin GHRH Modified GRF (1-29) Rismorelin Sermorelin Somatorelin Tesamorelin Antagonists: MZ-5-156 GHS (ghrelin) Agonists: Peptide: Alexamorelin Cortistatin-14

    Ipamorelin

    Ipamorelin

    Ipamorelin

  • Growth hormone

    • Peptide hormone that stimulates growth

    Dumorelin GHRH Modified GRF (1-29) Rismorelin Sermorelin Somatorelin Tesamorelin Antagonists: MZ-5-156 GHS (ghrelin) Agonists: Peptide: Alexamorelin Cortistatin-14

    Growth hormone

    Growth hormone

    Growth_hormone

  • List of banned substances in Major League Baseball

    • 176-191) and releasing factors including GHRHs (e.g., CJC-1295, sermorelin, tesamorelin), GHSs (e.g., ghrelin and its mimetics (e.g., anamorelin, ibutamoren

    List of banned substances in Major League Baseball

    List_of_banned_substances_in_Major_League_Baseball

  • GHRP-6

    • Chemical compound

    Dumorelin GHRH Modified GRF (1-29) Rismorelin Sermorelin Somatorelin Tesamorelin Antagonists: MZ-5-156 GHS (ghrelin) Agonists: Peptide: Alexamorelin Cortistatin-14

    GHRP-6

    GHRP-6

    GHRP-6

  • Anamorelin

    • Chemical compound

    Dumorelin GHRH Modified GRF (1-29) Rismorelin Sermorelin Somatorelin Tesamorelin Antagonists: MZ-5-156 GHS (ghrelin) Agonists: Peptide: Alexamorelin Cortistatin-14

    Anamorelin

    Anamorelin

    Anamorelin

  • HIV-associated lipodystrophy

    • Medical condition

    lost due to HIV-associated facial lipoatrophy. GHRH analogs such as tesamorelin can be used to treat HIV-associated lipodystrophy.[citation needed] Reversion

    HIV-associated lipodystrophy

    HIV-associated_lipodystrophy

  • List of investigational insomnia drugs

    • Investigational insomnia drugs

    channel inhibitor Tasipimidine (ODM-105) – α2A-adrenergic receptor agonist Tesamorelin (Egrifta; MDVTM; TH-9507; ThGRF 1-44) – growth hormone-releasing hormone

    List of investigational insomnia drugs

    List_of_investigational_insomnia_drugs

  • Sermorelin

    • Pharmaceutical drug

    Dumorelin GHRH Modified GRF (1-29) Rismorelin Sermorelin Somatorelin Tesamorelin Antagonists: MZ-5-156 GHS (ghrelin) Agonists: Peptide: Alexamorelin Cortistatin-14

    Sermorelin

    Sermorelin

    Sermorelin

  • Adenosine

    • Chemical compound

    Dumorelin GHRH Modified GRF (1-29) Rismorelin Sermorelin Somatorelin Tesamorelin Antagonists: MZ-5-156 GHS (ghrelin) Agonists: Peptide: Alexamorelin Cortistatin-14

    Adenosine

    Adenosine

    Adenosine

  • Growth-hormone-releasing hormone receptor

    • Receptor protein that binds with somatcrinin

    to date. CJC-1295 Dumorelin GHRH (somatorelin) Rismorelin Sermorelin Tesamorelin MZ-5-156 GRCh38: Ensembl release 89: ENSG00000106128 – Ensembl, May 2017

    Growth-hormone-releasing hormone receptor

    Growth-hormone-releasing hormone receptor

    Growth-hormone-releasing_hormone_receptor

  • Modified GRF (1-29)

    • Amino acid-like chemical compound

    Dumorelin GHRH Modified GRF (1-29) Rismorelin Sermorelin Somatorelin Tesamorelin Antagonists: MZ-5-156 GHS (ghrelin) Agonists: Peptide: Alexamorelin Cortistatin-14

    Modified GRF (1-29)

    Modified_GRF_(1-29)

  • List of designer drugs

    • stimulate the release of growth hormone. CJC-1293 CJC-1295 Sermorelin Tesamorelin Agonists of the growth hormone secretagogue receptor stimulate the release

    List of designer drugs

    List of designer drugs

    List_of_designer_drugs

  • Bovine somatotropin

    • Peptide hormone produced by cows' pituitary glands

    Dumorelin GHRH Modified GRF (1-29) Rismorelin Sermorelin Somatorelin Tesamorelin Antagonists: MZ-5-156 GHS (ghrelin) Agonists: Peptide: Alexamorelin Cortistatin-14

    Bovine somatotropin

    Bovine somatotropin

    Bovine_somatotropin

  • Somatostatin

    • Peptide hormone that regulates the endocrine system

    Dumorelin GHRH Modified GRF (1-29) Rismorelin Sermorelin Somatorelin Tesamorelin Antagonists: MZ-5-156 GHS (ghrelin) Agonists: Peptide: Alexamorelin Cortistatin-14

    Somatostatin

    Somatostatin

    Somatostatin

  • ATC code H01

    • Pharmaceutical drug classification

    H01AC03 Mecasermin H01AC04 Sermorelin H01AC05 Mecasermin rinfabate H01AC06 Tesamorelin H01AC07 Somapacitan H01AC08 Somatrogon H01AC09 Lonapegsomatropin H01AX01

    ATC code H01

    ATC_code_H01

  • Octreotide

    • Octapeptide that mimics natural somatostatin pharmacologically

    Dumorelin GHRH Modified GRF (1-29) Rismorelin Sermorelin Somatorelin Tesamorelin Antagonists: MZ-5-156 GHS (ghrelin) Agonists: Peptide: Alexamorelin Cortistatin-14

    Octreotide

    Octreotide

    Octreotide

  • List of drugs: Te

    • tertatolol (INN) tertomotide (USAN) terutroban (INN) tesaglitazar (USAN) tesamorelin (USAN) teserstigmine (INN) tesetaxel (INN) tesicam (INN) tesimide (INN)

    List of drugs: Te

    List_of_drugs:_Te

  • Pralmorelin

    • Chemical compound

    Dumorelin GHRH Modified GRF (1-29) Rismorelin Sermorelin Somatorelin Tesamorelin Antagonists: MZ-5-156 GHS (ghrelin) Agonists: Peptide: Alexamorelin Cortistatin-14

    Pralmorelin

    Pralmorelin

    Pralmorelin

  • Examorelin

    • Chemical compound

    200700015. PMID 17520591. S2CID 24945528. Wang Y, Tomlinson B (March 2009). "Tesamorelin, a human growth hormone releasing factor analogue". Expert Opinion on

    Examorelin

    Examorelin

    Examorelin

  • Ghrelin

    • Peptide hormone involved in appetite regulation

    Dumorelin GHRH Modified GRF (1-29) Rismorelin Sermorelin Somatorelin Tesamorelin Antagonists: MZ-5-156 GHS (ghrelin) Agonists: Peptide: Alexamorelin Cortistatin-14

    Ghrelin

    Ghrelin

    Ghrelin

  • Pegvisomant

    • Pharmaceutical drug

    Dumorelin GHRH Modified GRF (1-29) Rismorelin Sermorelin Somatorelin Tesamorelin Antagonists: MZ-5-156 GHS (ghrelin) Agonists: Peptide: Alexamorelin Cortistatin-14

    Pegvisomant

    Pegvisomant

  • Lanreotide

    • Pharmaceutical drug

    Dumorelin GHRH Modified GRF (1-29) Rismorelin Sermorelin Somatorelin Tesamorelin Antagonists: MZ-5-156 GHS (ghrelin) Agonists: Peptide: Alexamorelin Cortistatin-14

    Lanreotide

    Lanreotide

    Lanreotide

  • Growth hormone-binding protein

    • Protein fragment in Homo sapiens

    Dumorelin GHRH Modified GRF (1-29) Rismorelin Sermorelin Somatorelin Tesamorelin Antagonists: MZ-5-156 GHS (ghrelin) Agonists: Peptide: Alexamorelin Cortistatin-14

    Growth hormone-binding protein

    Growth_hormone-binding_protein

  • Pasireotide

    • Pharmaceutical drug

    Dumorelin GHRH Modified GRF (1-29) Rismorelin Sermorelin Somatorelin Tesamorelin Antagonists: MZ-5-156 GHS (ghrelin) Agonists: Peptide: Alexamorelin Cortistatin-14

    Pasireotide

    Pasireotide

    Pasireotide

  • Capromorelin

    • Chemical compound

    Dumorelin GHRH Modified GRF (1-29) Rismorelin Sermorelin Somatorelin Tesamorelin Antagonists: MZ-5-156 GHS (ghrelin) Agonists: Peptide: Alexamorelin Cortistatin-14

    Capromorelin

    Capromorelin

    Capromorelin

  • Somatrem

    • Pharmaceutical drug

    Dumorelin GHRH Modified GRF (1-29) Rismorelin Sermorelin Somatorelin Tesamorelin Antagonists: MZ-5-156 GHS (ghrelin) Agonists: Peptide: Alexamorelin Cortistatin-14

    Somatrem

    Somatrem

  • Growth hormone receptor

    • Protein involved in the binding of the growth hormone

    Dumorelin GHRH Modified GRF (1-29) Rismorelin Sermorelin Somatorelin Tesamorelin Antagonists: MZ-5-156 GHS (ghrelin) Agonists: Peptide: Alexamorelin Cortistatin-14

    Growth hormone receptor

    Growth hormone receptor

    Growth_hormone_receptor

  • Human placental lactogen

    • Polypeptide placental hormone in humans

    Dumorelin GHRH Modified GRF (1-29) Rismorelin Sermorelin Somatorelin Tesamorelin Antagonists: MZ-5-156 GHS (ghrelin) Agonists: Peptide: Alexamorelin Cortistatin-14

    Human placental lactogen

    Human placental lactogen

    Human_placental_lactogen

  • Tabimorelin

    • Chemical compound

    Dumorelin GHRH Modified GRF (1-29) Rismorelin Sermorelin Somatorelin Tesamorelin Antagonists: MZ-5-156 GHS (ghrelin) Agonists: Peptide: Alexamorelin Cortistatin-14

    Tabimorelin

    Tabimorelin

    Tabimorelin

  • Hypothalamic–pituitary–somatotropic axis

    • Hormone pathway

    Dumorelin GHRH Modified GRF (1-29) Rismorelin Sermorelin Somatorelin Tesamorelin Antagonists: MZ-5-156 GHS (ghrelin) Agonists: Peptide: Alexamorelin Cortistatin-14

    Hypothalamic–pituitary–somatotropic axis

    Hypothalamic–pituitary–somatotropic axis

    Hypothalamic–pituitary–somatotropic_axis

  • Somatorelin

    • Chemical compound

    Dumorelin GHRH Modified GRF (1-29) Rismorelin Sermorelin Somatorelin Tesamorelin Antagonists: MZ-5-156 GHS (ghrelin) Agonists: Peptide: Alexamorelin Cortistatin-14

    Somatorelin

    Somatorelin

  • Macimorelin

    • Chemical compound

    Dumorelin GHRH Modified GRF (1-29) Rismorelin Sermorelin Somatorelin Tesamorelin Antagonists: MZ-5-156 GHS (ghrelin) Agonists: Peptide: Alexamorelin Cortistatin-14

    Macimorelin

    Macimorelin

    Macimorelin

  • Somatostatin receptor 2

    • Protein-coding gene in the species Homo sapiens

    Dumorelin GHRH Modified GRF (1-29) Rismorelin Sermorelin Somatorelin Tesamorelin Antagonists: MZ-5-156 GHS (ghrelin) Agonists: Peptide: Alexamorelin Cortistatin-14

    Somatostatin receptor 2

    Somatostatin receptor 2

    Somatostatin_receptor_2

  • Growth hormone 2

    • Variant of somatotropin produced by placenta

    Dumorelin GHRH Modified GRF (1-29) Rismorelin Sermorelin Somatorelin Tesamorelin Antagonists: MZ-5-156 GHS (ghrelin) Agonists: Peptide: Alexamorelin Cortistatin-14

    Growth hormone 2

    Growth hormone 2

    Growth_hormone_2

  • SM-130686

    • Chemical compound

    Dumorelin GHRH Modified GRF (1-29) Rismorelin Sermorelin Somatorelin Tesamorelin Antagonists: MZ-5-156 GHS (ghrelin) Agonists: Peptide: Alexamorelin Cortistatin-14

    SM-130686

    SM-130686

    SM-130686

  • Vapreotide

    • Pharmaceutical drug

    Dumorelin GHRH Modified GRF (1-29) Rismorelin Sermorelin Somatorelin Tesamorelin Antagonists: MZ-5-156 GHS (ghrelin) Agonists: Peptide: Alexamorelin Cortistatin-14

    Vapreotide

    Vapreotide

    Vapreotide

  • Edotreotide

    • Chemical compound

    Dumorelin GHRH Modified GRF (1-29) Rismorelin Sermorelin Somatorelin Tesamorelin Antagonists: MZ-5-156 GHS (ghrelin) Agonists: Peptide: Alexamorelin Cortistatin-14

    Edotreotide

    Edotreotide

    Edotreotide

  • Somatostatin receptor

    • Cell surface protein binding somatostatin and triggering intracellular changes

    Dumorelin GHRH Modified GRF (1-29) Rismorelin Sermorelin Somatorelin Tesamorelin Antagonists: MZ-5-156 GHS (ghrelin) Agonists: Peptide: Alexamorelin Cortistatin-14

    Somatostatin receptor

    Somatostatin receptor

    Somatostatin_receptor

  • Lonapegsomatropin

    • Pharmaceutical compound

    Dumorelin GHRH Modified GRF (1-29) Rismorelin Sermorelin Somatorelin Tesamorelin Antagonists: MZ-5-156 GHS (ghrelin) Agonists: Peptide: Alexamorelin Cortistatin-14

    Lonapegsomatropin

    Lonapegsomatropin

  • Growth hormone 1

    • Hormone that regulates growth and development

    Dumorelin GHRH Modified GRF (1-29) Rismorelin Sermorelin Somatorelin Tesamorelin Antagonists: MZ-5-156 GHS (ghrelin) Agonists: Peptide: Alexamorelin Cortistatin-14

    Growth hormone 1

    Growth hormone 1

    Growth_hormone_1

  • Growth hormone secretagogue receptor

    • Protein-coding gene in the species Homo sapiens

    Dumorelin GHRH Modified GRF (1-29) Rismorelin Sermorelin Somatorelin Tesamorelin Antagonists: MZ-5-156 GHS (ghrelin) Agonists: Peptide: Alexamorelin Cortistatin-14

    Growth hormone secretagogue receptor

    Growth hormone secretagogue receptor

    Growth_hormone_secretagogue_receptor

  • Relamorelin

    • Chemical compound

    Dumorelin GHRH Modified GRF (1-29) Rismorelin Sermorelin Somatorelin Tesamorelin Antagonists: MZ-5-156 GHS (ghrelin) Agonists: Peptide: Alexamorelin Cortistatin-14

    Relamorelin

    Relamorelin

    Relamorelin

  • Octreotate

    • Chemical compound

    Dumorelin GHRH Modified GRF (1-29) Rismorelin Sermorelin Somatorelin Tesamorelin Antagonists: MZ-5-156 GHS (ghrelin) Agonists: Peptide: Alexamorelin Cortistatin-14

    Octreotate

    Octreotate

    Octreotate

  • Ulimorelin

    • Chemical compound

    Dumorelin GHRH Modified GRF (1-29) Rismorelin Sermorelin Somatorelin Tesamorelin Antagonists: MZ-5-156 GHS (ghrelin) Agonists: Peptide: Alexamorelin Cortistatin-14

    Ulimorelin

    Ulimorelin

    Ulimorelin

  • Somatostatin receptor 5

    • Protein-coding gene in the species Homo sapiens

    Dumorelin GHRH Modified GRF (1-29) Rismorelin Sermorelin Somatorelin Tesamorelin Antagonists: MZ-5-156 GHS (ghrelin) Agonists: Peptide: Alexamorelin Cortistatin-14

    Somatostatin receptor 5

    Somatostatin receptor 5

    Somatostatin_receptor_5

  • Somatostatin receptor 4

    • Protein-coding gene in the species Homo sapiens

    Dumorelin GHRH Modified GRF (1-29) Rismorelin Sermorelin Somatorelin Tesamorelin Antagonists: MZ-5-156 GHS (ghrelin) Agonists: Peptide: Alexamorelin Cortistatin-14

    Somatostatin receptor 4

    Somatostatin receptor 4

    Somatostatin_receptor_4

  • Somatostatin receptor 1

    • Protein-coding gene in the species Homo sapiens

    Dumorelin GHRH Modified GRF (1-29) Rismorelin Sermorelin Somatorelin Tesamorelin Antagonists: MZ-5-156 GHS (ghrelin) Agonists: Peptide: Alexamorelin Cortistatin-14

    Somatostatin receptor 1

    Somatostatin receptor 1

    Somatostatin_receptor_1

  • Somatostatin receptor 3

    • Protein-coding gene in the species Homo sapiens

    Dumorelin GHRH Modified GRF (1-29) Rismorelin Sermorelin Somatorelin Tesamorelin Antagonists: MZ-5-156 GHS (ghrelin) Agonists: Peptide: Alexamorelin Cortistatin-14

    Somatostatin receptor 3

    Somatostatin receptor 3

    Somatostatin_receptor_3

  • Somatomedin receptor

    • Cell surface receptors that bind somatomedins

    Dumorelin GHRH Modified GRF (1-29) Rismorelin Sermorelin Somatorelin Tesamorelin Antagonists: MZ-5-156 GHS (ghrelin) Agonists: Peptide: Alexamorelin Cortistatin-14

    Somatomedin receptor

    Somatomedin_receptor

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TESAMORELIN

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TESAMORELIN