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SM 130686

  • SM-130686

    • Chemical compound

    SM-130686 is a small-molecule drug which acts as a potent, orally-active agonist of the ghrelin/growth hormone secretagogue receptor (GHSR) and growth

    SM-130686

    SM-130686

    SM-130686

  • Growth hormone secretagogue

    • Class of drugs

    (MK-677, MK-0677, L-163191, LUM-201) Macimorelin (AEZS-130, JMV 1843) SM-130686 Note that while ulimorelin is a ghrelin receptor agonist, it is not a

    Growth hormone secretagogue

    Growth_hormone_secretagogue

  • Ibutamoren

    • Experimental drug

    Anamorelin Capromorelin CP-464709 Ibutamoren (MK-677) L-692,585 Macimorelin SM-130686; Unsorted: LY-426410 LY-444711 Antagonists: A-778193 Cortistatin-8 (D-Lys³)-GHRP-6

    Ibutamoren

    Ibutamoren

    Ibutamoren

  • Ipamorelin

    • Peptide selective agonist of the ghrelin/growth hormone secretagogue receptor

    Anamorelin Capromorelin CP-464709 Ibutamoren (MK-677) L-692,585 Macimorelin SM-130686; Unsorted: LY-426410 LY-444711 Antagonists: A-778193 Cortistatin-8 (D-Lys³)-GHRP-6

    Ipamorelin

    Ipamorelin

    Ipamorelin

  • CJC-1295

    • Chemical compound

    Anamorelin Capromorelin CP-464709 Ibutamoren (MK-677) L-692,585 Macimorelin SM-130686; Unsorted: LY-426410 LY-444711 Antagonists: A-778193 Cortistatin-8 (D-Lys³)-GHRP-6

    CJC-1295

    CJC-1295

  • Tesamorelin

    • Pharmaceutical drug

    Anamorelin Capromorelin CP-464709 Ibutamoren (MK-677) L-692,585 Macimorelin SM-130686; Unsorted: LY-426410 LY-444711 Antagonists: A-778193 Cortistatin-8 (D-Lys³)-GHRP-6

    Tesamorelin

    Tesamorelin

    Tesamorelin

  • Growth hormone

    • Peptide hormone that stimulates growth

    ISBN 978-1455772551. Molitch ME, Clemmons DR, Malozowski S, Merriam GR, Shalet SM, Vance ML, Stephens PA (May 2006). "Evaluation and treatment of adult growth

    Growth hormone

    Growth hormone

    Growth_hormone

  • Sermorelin

    • Pharmaceutical drug

    Anamorelin Capromorelin CP-464709 Ibutamoren (MK-677) L-692,585 Macimorelin SM-130686; Unsorted: LY-426410 LY-444711 Antagonists: A-778193 Cortistatin-8 (D-Lys³)-GHRP-6

    Sermorelin

    Sermorelin

    Sermorelin

  • Vapreotide

    • Pharmaceutical drug

    Anamorelin Capromorelin CP-464709 Ibutamoren (MK-677) L-692,585 Macimorelin SM-130686; Unsorted: LY-426410 LY-444711 Antagonists: A-778193 Cortistatin-8 (D-Lys³)-GHRP-6

    Vapreotide

    Vapreotide

    Vapreotide

  • Somatostatin

    • Peptide hormone that regulates the endocrine system

    Anamorelin Capromorelin CP-464709 Ibutamoren (MK-677) L-692,585 Macimorelin SM-130686; Unsorted: LY-426410 LY-444711 Antagonists: A-778193 Cortistatin-8 (D-Lys³)-GHRP-6

    Somatostatin

    Somatostatin

    Somatostatin

  • Adenosine

    • Chemical compound

    Anamorelin Capromorelin CP-464709 Ibutamoren (MK-677) L-692,585 Macimorelin SM-130686; Unsorted: LY-426410 LY-444711 Antagonists: A-778193 Cortistatin-8 (D-Lys³)-GHRP-6

    Adenosine

    Adenosine

    Adenosine

  • Lanreotide

    • Pharmaceutical drug

    Anamorelin Capromorelin CP-464709 Ibutamoren (MK-677) L-692,585 Macimorelin SM-130686; Unsorted: LY-426410 LY-444711 Antagonists: A-778193 Cortistatin-8 (D-Lys³)-GHRP-6

    Lanreotide

    Lanreotide

    Lanreotide

  • Growth hormone–releasing hormone

    • Mammalian protein found in Homo sapiens

    Anamorelin Capromorelin CP-464709 Ibutamoren (MK-677) L-692,585 Macimorelin SM-130686; Unsorted: LY-426410 LY-444711 Antagonists: A-778193 Cortistatin-8 (D-Lys³)-GHRP-6

    Growth hormone–releasing hormone

    Growth_hormone–releasing_hormone

  • Capromorelin

    • Chemical compound

    Administration (FDA). Retrieved 12 December 2022. Carpino PA, Lefker BA, Toler SM, Pan LC, Hadcock JR, Murray MC, et al. (November 2002). "Discovery and biological

    Capromorelin

    Capromorelin

    Capromorelin

  • Ghrelin

    • Peptide hormone involved in appetite regulation

    1016/0306-4522(93)90197-n. PMID 8492908. S2CID 9757253. Dickson SL, Luckman SM (February 1997). "Induction of c-fos messenger ribonucleic acid in neuropeptide

    Ghrelin

    Ghrelin

    Ghrelin

  • Growth hormone 2

    • Variant of somatotropin produced by placenta

    Anamorelin Capromorelin CP-464709 Ibutamoren (MK-677) L-692,585 Macimorelin SM-130686; Unsorted: LY-426410 LY-444711 Antagonists: A-778193 Cortistatin-8 (D-Lys³)-GHRP-6

    Growth hormone 2

    Growth hormone 2

    Growth_hormone_2

  • Macimorelin

    • Chemical compound

    Anamorelin Capromorelin CP-464709 Ibutamoren (MK-677) L-692,585 Macimorelin SM-130686; Unsorted: LY-426410 LY-444711 Antagonists: A-778193 Cortistatin-8 (D-Lys³)-GHRP-6

    Macimorelin

    Macimorelin

    Macimorelin

  • Human placental lactogen

    • Polypeptide placental hormone in humans

    Anamorelin Capromorelin CP-464709 Ibutamoren (MK-677) L-692,585 Macimorelin SM-130686; Unsorted: LY-426410 LY-444711 Antagonists: A-778193 Cortistatin-8 (D-Lys³)-GHRP-6

    Human placental lactogen

    Human placental lactogen

    Human_placental_lactogen

  • Examorelin

    • Chemical compound

    doi:10.1210/jcem.80.4.7714074. PMID 7714074. Rahim A, O'Neill PA, Shalet SM (May 1998). "Growth hormone status during long-term hexarelin therapy". The

    Examorelin

    Examorelin

    Examorelin

  • Tabimorelin

    • Chemical compound

    Anamorelin Capromorelin CP-464709 Ibutamoren (MK-677) L-692,585 Macimorelin SM-130686; Unsorted: LY-426410 LY-444711 Antagonists: A-778193 Cortistatin-8 (D-Lys³)-GHRP-6

    Tabimorelin

    Tabimorelin

    Tabimorelin

  • GHRP-6

    • Chemical compound

    Anamorelin Capromorelin CP-464709 Ibutamoren (MK-677) L-692,585 Macimorelin SM-130686; Unsorted: LY-426410 LY-444711 Antagonists: A-778193 Cortistatin-8 (D-Lys³)-GHRP-6

    GHRP-6

    GHRP-6

    GHRP-6

  • Hypothalamic–pituitary–somatotropic axis

    • Hormone pathway

    Anamorelin Capromorelin CP-464709 Ibutamoren (MK-677) L-692,585 Macimorelin SM-130686; Unsorted: LY-426410 LY-444711 Antagonists: A-778193 Cortistatin-8 (D-Lys³)-GHRP-6

    Hypothalamic–pituitary–somatotropic axis

    Hypothalamic–pituitary–somatotropic axis

    Hypothalamic–pituitary–somatotropic_axis

  • Somatorelin

    • Chemical compound

    Anamorelin Capromorelin CP-464709 Ibutamoren (MK-677) L-692,585 Macimorelin SM-130686; Unsorted: LY-426410 LY-444711 Antagonists: A-778193 Cortistatin-8 (D-Lys³)-GHRP-6

    Somatorelin

    Somatorelin

  • Lonapegsomatropin

    • Pharmaceutical compound

    Anamorelin Capromorelin CP-464709 Ibutamoren (MK-677) L-692,585 Macimorelin SM-130686; Unsorted: LY-426410 LY-444711 Antagonists: A-778193 Cortistatin-8 (D-Lys³)-GHRP-6

    Lonapegsomatropin

    Lonapegsomatropin

  • Growth hormone-binding protein

    • Protein fragment in Homo sapiens

    Anamorelin Capromorelin CP-464709 Ibutamoren (MK-677) L-692,585 Macimorelin SM-130686; Unsorted: LY-426410 LY-444711 Antagonists: A-778193 Cortistatin-8 (D-Lys³)-GHRP-6

    Growth hormone-binding protein

    Growth_hormone-binding_protein

  • Edotreotide

    • Chemical compound

    for radiopharmaceutical preparation - Summary of Product Characteristics (SmPC)". (emc). 2 July 2021. Retrieved 9 July 2021. "SomaKit TOC EPAR". European

    Edotreotide

    Edotreotide

    Edotreotide

  • Growth hormone therapy

    • Type of hormone therapy

    Anamorelin Capromorelin CP-464709 Ibutamoren (MK-677) L-692,585 Macimorelin SM-130686; Unsorted: LY-426410 LY-444711 Antagonists: A-778193 Cortistatin-8 (D-Lys³)-GHRP-6

    Growth hormone therapy

    Growth_hormone_therapy

  • Anamorelin

    • Chemical compound

    Anamorelin Capromorelin CP-464709 Ibutamoren (MK-677) L-692,585 Macimorelin SM-130686; Unsorted: LY-426410 LY-444711 Antagonists: A-778193 Cortistatin-8 (D-Lys³)-GHRP-6

    Anamorelin

    Anamorelin

    Anamorelin

  • Somatrem

    • Pharmaceutical drug

    Anamorelin Capromorelin CP-464709 Ibutamoren (MK-677) L-692,585 Macimorelin SM-130686; Unsorted: LY-426410 LY-444711 Antagonists: A-778193 Cortistatin-8 (D-Lys³)-GHRP-6

    Somatrem

    Somatrem

  • Pasireotide

    • Pharmaceutical drug

    Anamorelin Capromorelin CP-464709 Ibutamoren (MK-677) L-692,585 Macimorelin SM-130686; Unsorted: LY-426410 LY-444711 Antagonists: A-778193 Cortistatin-8 (D-Lys³)-GHRP-6

    Pasireotide

    Pasireotide

    Pasireotide

  • Growth hormone receptor

    • Protein involved in the binding of the growth hormone

    (5): 571–93. doi:10.1080/10635150390235368. PMID 14530127. Koepfli KP, Jenks SM, Eizirik E, Zahirpour T, Van Valkenburgh B, Wayne RK (March 2006). "Molecular

    Growth hormone receptor

    Growth hormone receptor

    Growth_hormone_receptor

  • Pralmorelin

    • Chemical compound

    Anamorelin Capromorelin CP-464709 Ibutamoren (MK-677) L-692,585 Macimorelin SM-130686; Unsorted: LY-426410 LY-444711 Antagonists: A-778193 Cortistatin-8 (D-Lys³)-GHRP-6

    Pralmorelin

    Pralmorelin

    Pralmorelin

  • Octreotide

    • Octapeptide that mimics natural somatostatin pharmacologically

    Anamorelin Capromorelin CP-464709 Ibutamoren (MK-677) L-692,585 Macimorelin SM-130686; Unsorted: LY-426410 LY-444711 Antagonists: A-778193 Cortistatin-8 (D-Lys³)-GHRP-6

    Octreotide

    Octreotide

    Octreotide

  • Somatostatin receptor

    • Cell surface protein binding somatostatin and triggering intracellular changes

    Anamorelin Capromorelin CP-464709 Ibutamoren (MK-677) L-692,585 Macimorelin SM-130686; Unsorted: LY-426410 LY-444711 Antagonists: A-778193 Cortistatin-8 (D-Lys³)-GHRP-6

    Somatostatin receptor

    Somatostatin receptor

    Somatostatin_receptor

  • Bovine somatotropin

    • Peptide hormone produced by cows' pituitary glands

    Anamorelin Capromorelin CP-464709 Ibutamoren (MK-677) L-692,585 Macimorelin SM-130686; Unsorted: LY-426410 LY-444711 Antagonists: A-778193 Cortistatin-8 (D-Lys³)-GHRP-6

    Bovine somatotropin

    Bovine somatotropin

    Bovine_somatotropin

  • Modified GRF (1-29)

    • Amino acid-like chemical compound

    Anamorelin Capromorelin CP-464709 Ibutamoren (MK-677) L-692,585 Macimorelin SM-130686; Unsorted: LY-426410 LY-444711 Antagonists: A-778193 Cortistatin-8 (D-Lys³)-GHRP-6

    Modified GRF (1-29)

    Modified_GRF_(1-29)

  • Relamorelin

    • Chemical compound

    Anamorelin Capromorelin CP-464709 Ibutamoren (MK-677) L-692,585 Macimorelin SM-130686; Unsorted: LY-426410 LY-444711 Antagonists: A-778193 Cortistatin-8 (D-Lys³)-GHRP-6

    Relamorelin

    Relamorelin

    Relamorelin

  • Ulimorelin

    • Chemical compound

    Anamorelin Capromorelin CP-464709 Ibutamoren (MK-677) L-692,585 Macimorelin SM-130686; Unsorted: LY-426410 LY-444711 Antagonists: A-778193 Cortistatin-8 (D-Lys³)-GHRP-6

    Ulimorelin

    Ulimorelin

    Ulimorelin

  • Growth hormone secretagogue receptor

    • Protein-coding gene in the species Homo sapiens

    L-692,585 LY-426410 LY-444711 Macimorelin Pralmorelin (GHRP-2) Relamorelin SM-130,686 Tabimorelin Ulimorelin A-778,193 PF-5190457 GRCh38: Ensembl release

    Growth hormone secretagogue receptor

    Growth hormone secretagogue receptor

    Growth_hormone_secretagogue_receptor

  • Growth hormone 1

    • Hormone that regulates growth and development

    Anamorelin Capromorelin CP-464709 Ibutamoren (MK-677) L-692,585 Macimorelin SM-130686; Unsorted: LY-426410 LY-444711 Antagonists: A-778193 Cortistatin-8 (D-Lys³)-GHRP-6

    Growth hormone 1

    Growth hormone 1

    Growth_hormone_1

  • Growth-hormone-releasing hormone receptor

    • Receptor protein that binds with somatcrinin

    Anamorelin Capromorelin CP-464709 Ibutamoren (MK-677) L-692,585 Macimorelin SM-130686; Unsorted: LY-426410 LY-444711 Antagonists: A-778193 Cortistatin-8 (D-Lys³)-GHRP-6

    Growth-hormone-releasing hormone receptor

    Growth-hormone-releasing hormone receptor

    Growth-hormone-releasing_hormone_receptor

  • Somatomedin receptor

    • Cell surface receptors that bind somatomedins

    Anamorelin Capromorelin CP-464709 Ibutamoren (MK-677) L-692,585 Macimorelin SM-130686; Unsorted: LY-426410 LY-444711 Antagonists: A-778193 Cortistatin-8 (D-Lys³)-GHRP-6

    Somatomedin receptor

    Somatomedin_receptor

  • Somatostatin receptor 5

    • Protein-coding gene in the species Homo sapiens

    Anamorelin Capromorelin CP-464709 Ibutamoren (MK-677) L-692,585 Macimorelin SM-130686; Unsorted: LY-426410 LY-444711 Antagonists: A-778193 Cortistatin-8 (D-Lys³)-GHRP-6

    Somatostatin receptor 5

    Somatostatin receptor 5

    Somatostatin_receptor_5

  • Octreotate

    • Chemical compound

    Anamorelin Capromorelin CP-464709 Ibutamoren (MK-677) L-692,585 Macimorelin SM-130686; Unsorted: LY-426410 LY-444711 Antagonists: A-778193 Cortistatin-8 (D-Lys³)-GHRP-6

    Octreotate

    Octreotate

    Octreotate

  • Pegvisomant

    • Pharmaceutical drug

    doi:10.1159/000381644. PMID 25792221. S2CID 19588354. Evans A, Jamieson SM, Liu DX, Wilson WR, Perry JK (August 2016). "Growth hormone receptor antagonism

    Pegvisomant

    Pegvisomant

  • Somatostatin receptor 2

    • Protein-coding gene in the species Homo sapiens

    Anamorelin Capromorelin CP-464709 Ibutamoren (MK-677) L-692,585 Macimorelin SM-130686; Unsorted: LY-426410 LY-444711 Antagonists: A-778193 Cortistatin-8 (D-Lys³)-GHRP-6

    Somatostatin receptor 2

    Somatostatin receptor 2

    Somatostatin_receptor_2

  • Somatostatin receptor 1

    • Protein-coding gene in the species Homo sapiens

    Anamorelin Capromorelin CP-464709 Ibutamoren (MK-677) L-692,585 Macimorelin SM-130686; Unsorted: LY-426410 LY-444711 Antagonists: A-778193 Cortistatin-8 (D-Lys³)-GHRP-6

    Somatostatin receptor 1

    Somatostatin receptor 1

    Somatostatin_receptor_1

  • Somatostatin receptor 3

    • Protein-coding gene in the species Homo sapiens

    Anamorelin Capromorelin CP-464709 Ibutamoren (MK-677) L-692,585 Macimorelin SM-130686; Unsorted: LY-426410 LY-444711 Antagonists: A-778193 Cortistatin-8 (D-Lys³)-GHRP-6

    Somatostatin receptor 3

    Somatostatin receptor 3

    Somatostatin_receptor_3

  • Somatostatin receptor 4

    • Protein-coding gene in the species Homo sapiens

    Anamorelin Capromorelin CP-464709 Ibutamoren (MK-677) L-692,585 Macimorelin SM-130686; Unsorted: LY-426410 LY-444711 Antagonists: A-778193 Cortistatin-8 (D-Lys³)-GHRP-6

    Somatostatin receptor 4

    Somatostatin receptor 4

    Somatostatin_receptor_4

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SM 130686

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