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Medical diagnostic method
Plasma renin activity (PRA), also known as the renin (active) assay or random plasma renin, is a measure of the activity of the plasma enzyme renin, which
Plasma_renin_activity
Aspartic protease protein and enzyme
participates in the body's renin–angiotensin–aldosterone system (RAAS), which increases the volume of extracellular fluid (blood plasma, lymph, and interstitial
Renin
Blood concentration
Aldosterone-to-renin ratio (ARR) is the mass concentration of aldosterone divided by the plasma renin activity or by serum renin concentration in blood
Aldosterone-to-renin_ratio
Kidney disease
lower limbs, and the heart. Plasma renin activity is also known as renin assay. This assay measures the activity of renin, also known as angiotensinogenase
Kidney_ischemia
Medical condition
potassium levels (hypokalemia), metabolic alkalosis, and low levels of plasma renin activity (PRA). However, unlike hyperaldosteronism, this conditions exhibits
Pseudohyperaldosteronism
Blood pressure medication
the renin–angiotensin system. As a result of losartan dosing, plasma renin activity increases due to the removal of the angiotensin II feedback. Renin is
Losartan
Mineralocorticoid steroid hormone
secreted by the heart. Aldosterone is part of the renin–angiotensin–aldosterone system. It has a plasma half-life of less than 20 minutes. Drugs that interfere
Aldosterone
Hormone system
prorenin (already present in the blood) into renin and secrete it directly into the circulation. Plasma renin then carries out the conversion of angiotensinogen
Renin–angiotensin_system
Compound inhibiting the activity of renin
Renin inhibitors are pharmaceutical drugs inhibiting the activity of renin that is responsible for hydrolyzing angiotensinogen to angiotensin I, which
Renin_inhibitor
Cancer of the adrenal cortex
turn produce muscle weakness, confusion, and palpitations), low plasma renin activity, and high serum aldosterone. Feminization (estrogen excess) is most
Adrenocortical_carcinoma
Topics referred to by the same term
biochemical intermediate Physical Review A, a scientific journal Plasma renin activity in medicine Positive relative accommodation Primitive recursive
PRA
Endocrine disorder of a lack of the hormone aldosterone
hypoaldersteronism may be suspected if renin activity is low with low aldosterone concentrations. The plasma aldosterone-to-renin ratio is calculated to determine
Hypoaldosteronism
Common human medical data ranges for blood test results
(March 1988). "Different secretory pathways of renin from mouse cells transfected with the human renin gene". The Journal of Biological Chemistry. 263
Reference ranges for blood tests
Reference_ranges_for_blood_tests
Alpha-adrenergic agonist
brainstem, which lowers peripheral vascular resistance, heart rate and plasma renin activity, thereby reducing systolic and diastolic blood pressure as a consequence
Clonidine
Medical condition
include hypertension, hypokalemia, metabolic alkalosis, and low plasma renin activity. DOC excess syndrome is an excessive secretion of 21-hydroxyprogesterone
Apparent mineralocorticoid excess syndrome
Apparent_mineralocorticoid_excess_syndrome
Medication to treat high blood pressure and alopecia
brings an increase in plasma renin activity, largely due to the aforementioned activation of the SNS. This activation of the renin-angiotensin axis further
Minoxidil
Long-term high blood pressure in the arteries
plasma renin activity (PRA) is plotted against 24-h sodium excretion, ~10–15% of hypertensive patients have high PRA and 25% have low PRA. High-renin
Hypertension
State of steady internal conditions maintained by living things
Gauntner WC (March 1979). "Effect of potassium chloride on plasma renin activity and plasma aldosterone during sodium restriction in normal man". Kidney
Homeostasis
Medical condition
and frequently severe, high blood pressure associated with low plasma renin activity, metabolic alkalosis, low blood potassium, and normal to low levels
Liddle's_syndrome
prothrombin ratio p.r. per rectum (as noun: rectal examination) PRA plasma renin activity PRBC PRBCs packed red blood cells PREA Pediatric Research Equity
List of medical abbreviations: P
List_of_medical_abbreviations:_P
Anti-inflammatory drug
indometacin, also increase plasma renin activity and aldosterone levels, and increase sodium and potassium retention. Vasopressin activity is also enhanced. Together
Indometacin
Hormonal disorder in cats
computerized tomography (CT). The ratio of plasma aldosterone concentration (PAC) to plasma renin activity (PRA) can be used as a screening test for PHA
Feline_hyperaldosteronism
Chemical compound
Gauntner WC (March 1979). "Effect of potassium chloride on plasma renin activity and plasma aldosterone during sodium restriction in normal man". Kidney
11-Deoxycorticosterone
Medical condition
hydrocortisone. Mineralocorticoid is only added in cases where the plasma renin activity is high. Most patients that have the nonclassic form do not require
Congenital adrenal hyperplasia due to 21-hydroxylase deficiency
Congenital_adrenal_hyperplasia_due_to_21-hydroxylase_deficiency
Unanticipated finding unrelated to the original inquiry
fractionated metanephrines and catecholamines Blood plasma aldosterone concentration and plasma renin activity, if hypertension is present On CT scan, benign
Incidental_imaging_finding
Group of peptide hormones in mammals
causes vasoconstriction and an increase in blood pressure. It is part of the renin–angiotensin system, which regulates blood pressure. Angiotensin also stimulates
Angiotensin
Human arterial disease
controlled blood pressure, which is often signified by reductions in plasma renin activity and angiotensin II levels, and when compared with surgery, percutaneous
Fibromuscular_dysplasia
Medical condition
Garovic VD, Hilliard AA, Turner ST (November 2006). "Monogenic forms of low-renin hypertension". Nature Clinical Practice. Nephrology. 2 (11). Nature Clinical
Pseudohypoaldosteronism
Measurement of blood oxygen saturation
Ishii M, Ohno K (March 1977). "Comparisons of body fluid volumes, plasma renin activity, hemodynamics and pressor responsiveness between juvenile and aged
Pulse_oximetry
Medication drug
antimineralocorticoid activity, drospirenone increases natriuresis, decreases water retention and blood pressure, and produces compensatory increases in plasma renin activity
Drospirenone
Failure of the placenta to deliver sufficient nutrients to the fetus during pregnancy
digoxin-like immunoreactive substance, norepinephrine, epinephrine, and plasma renin activity in human fetuses and their alteration by fetal disease". American
Placental_insufficiency
Tumors of the adrenal gland
fractionated metanephrines and catecholamines Blood plasma aldosterone concentration and plasma renin activity, if hypertension is present Metastasis, or mets
Adrenal_tumor
High blood pressure without an identifiable cause
in renin secretion. This is one possible mechanism of explaining the observed link between hypertension and vitamin D levels in the blood plasma. Also
Essential_hypertension
lower blood pressure by a RAAS independent mechanism, reducing plasma renin activity and Ang II levels. Propranolol, Atenolol, Bupranolol, Timolol, are
Hypertension_and_the_brain
Canadian physician
in patients in three hypertension clinics in Africa, measuring plasma renin activity and aldosterone markedly improved blood pressure control, but permitting
John_David_Spence
Medication used to treat hypertension and heart failure
of pregnancy as it may harm the baby. Lisinopril works by inhibiting the renin–angiotensin–aldosterone system. Lisinopril was patented in 1978 and approved
Lisinopril
Protein-coding gene in the species Homo sapiens
correction, moderate decrease of blood pressure, and an increase plasma renin activity in patients who are on a low-sodium diet. Ongoing medical research is
Aldosterone_synthase
Chemical compound
axis (HPA axis), increased prolactin secretion, and increased plasma renin activity. In addition, it increases oxytocin levels. PCA and other SRAs like
Para-Chloroamphetamine
Drug class
characterization of serotonin receptor subtypes involved in vasopressin and plasma renin activity responses to serotonin agonists". European Journal of Pharmacology
5-HT2C_receptor_agonist
Chemical compound
normal, or low renin plasma concentrations, although acebutolol may be more efficient in patients with high or normal renin plasma concentrations. In
Acebutolol
Physiological processes of hypertension
and other enzymes, including the serine protease chymase. The activity of local renin–angiotensin systems and alternative pathways of angiotensin II
Pathophysiology of hypertension
Pathophysiology_of_hypertension
Chemical compound
"Physiologic mechanisms of bupicomide- and hydralazine-induced increase in plasma renin activity in hypertensive patients". Mayo Clinic Proceedings. 52 (7): 430–2
Bupicomide
Human disease
development of HRS in cirrhotics have been identified: liver size, plasma renin activity, and serum sodium concentration. The prognosis of these patients
Hepatorenal_syndrome
Hormone whose molecules are peptides
hormone (MSH) Orexin/Hypocretin Oxytocin Parathyroid hormone (PTH) Prolactin Renin Somatostatin Thyroid-stimulating hormone (TSH) Thyrotropin-releasing hormone
Peptide_hormone
Australian medical researcher
"Alteration by oral contraceptives of normal menstrual changes in plasma renin activity, concentration and substrate". Clinical Science. 36 (1): 67–76.
Eugenie_Lumbers
Medication class with multiple uses
sympatholytic β1 activity in the heart, influence the renin–angiotensin system at the kidneys. Beta blockers cause a decrease in renin secretion, which
Beta_blocker
Medication against high blood pressure
pressure. Aliskiren is a renin inhibitor, which works to reduce primary hypertension (that with no known cause) by binding to renin and preventing it from
Amlodipine
Medication used to treat high blood pressure and heart failure
safe. It is an ACE inhibitor and works by decreasing renin-angiotensin-aldosterone system activity. Benazepril was patented in 1981 and came into medical
Benazepril
Medication
blood potassium, and metabolic alkalosis in conjunction with a low plasma renin activity and a low aldosterone. Some people with the Liddle phenotype have
Amiloride
Medication
thereby increasing plasma volume, and thus blood pressure. Aliskiren binds to the S3bp binding site of renin, essential for its activity. Binding to this
Aliskiren
Class of medications used primarily to treat high blood pressure
the heart. ACE inhibitors inhibit the activity of angiotensin-converting enzyme, an important component of the renin–angiotensin system which converts angiotensin
ACE_inhibitor
Protein-coding gene in the species Homo sapiens
early onset hypertension, metabolic alkalosis and low levels of plasma renin activity and mineralocorticoid hormone aldosterone. In the absence of a recognizable
SCNN1G
Beta-1 selective adrenenergic blocker medication used to treat cardiovascular diseases
nebivolol is approximately 3.5 times more β1-selective. Bisoprolol inhibits renin secretion by about 65% and tachycardia by about 30%. After ingestion, bisoprolol
Bisoprolol
Blood pressure medication
Telmisartan is contraindicated during pregnancy. Telmisartan affects the renin–angiotensin system and can cause birth defects, stillbirths, and neonatal
Telmisartan
Mammalian protein found in humans
Angiotensin-converting enzyme (EC 3.4.15.1), or ACE, is a central component of the renin–angiotensin system (RAS), which controls blood pressure by regulating the
Angiotensin-converting_enzyme
Group of antihypertensive drugs
harm the heart and kidneys, and individuals with high levels of renin activity in plasma were at increased risk of myocardial infarction and stroke. With
Discovery and development of angiotensin receptor blockers
Discovery_and_development_of_angiotensin_receptor_blockers
Negative feedback mechanism regulating the glomerular filtration rate
increased renin release, which leads to restoration of plasma volume, and to dilation of the afferent arterioles, which leads to increased renal plasma flow
Tubuloglomerular_feedback
Mammalian protein found in humans
phosphate (HPO42−) from the tubular fluid, resulting in a decrease in the plasma phosphate concentration. Phosphate ions form water-insoluble salts with
Parathyroid_hormone
Cardiac hormone which increases renal sodium excretion
There are three volume regulating systems: two salt saving systems, the renin angiotensin aldosterone system (RAAS) and the renal sympathetic system (RSS);
Atrial_natriuretic_peptide
Angiotensin II receptor antagonist
volume depletion whose renal function is in part dependent on the activity of the renin-angiotensin system like efferent arteriolar vasoconstriction done
Valsartan
Protein-coding gene in the species Homo sapiens
of peripheral noradrenergic activity, vascular smooth muscle cells proliferation, decreased renal blood flow, renal renin inhibition, renal tubular sodium
Angiotensin II receptor type 1
Angiotensin_II_receptor_type_1
Exopeptidase enzyme that acts on angiotensin I and II
(sACE2). Both membrane bound and soluble ACE2 are integral parts of the renin–angiotensin–aldosterone system (RAAS) that exists to keep the body's blood
Angiotensin-converting enzyme 2
Angiotensin-converting_enzyme_2
ACE inhibitor used in the treatment of hypertension and congestive heart failure
drugs called ACE inhibitors and works by decreasing renin-angiotensin-aldosterone system activity. Quinapril was patented in 1980 and came into medical
Quinapril
Medical condition
aldosterone release from the adrenal cortex:[citation needed] The role of the renin–angiotensin system: Angiotensin is involved in regulating aldosterone and
Glucocorticoid remediable aldosteronism
Glucocorticoid_remediable_aldosteronism
Widening of blood vessels
nervous system activity, reduced blood volume or reduced arterial pressure trigger β-adrenergic receptors in select kidney cells to release renin, which converts
Vasodilation
Hormone-producing glands of a body
pituitary. TRH – TSH – T3/T4 GnRH – LH/FSH – sex hormones CRH – ACTH – cortisol Renin – angiotensin – aldosterone Leptin vs. ghrelin Endocrine glands are glands
Endocrine_system
Protein-coding gene in the species Homo sapiens
early onset hypertension, metabolic alkalosis and low levels of plasma renin activity and mineralocorticoid hormone aldosterone. In the absence of a recognizable
SCNN1B
American physician (1920–1999)
Tarazi, R. C.; Frohlich, E. D. (1970). "Functional correlates of plasma renin activity in hypertensive patients. - Semantic Scholar". Circulation. 41 (3):
Harriet_P._Dustan
Excess production of aldosterone in the adrenal gland
production of the hormone aldosterone from the adrenal glands, resulting in low renin levels and high blood pressure. This abnormality is a paraneoplastic syndrome
Primary_aldosteronism
Mineralocorticoid medication
a prodrug of fludrocortisone, which is the active form of the drug. Plasma renin, sodium, and potassium are checked through blood tests to verify that
Fludrocortisone
Antihypertensive drug of the ACE inhibitor class
within the renin-angiotensin system. Captopril's main uses are based on its vasodilation and inhibition of some renal function activities. These benefits
Captopril
Difference in quantities of cations and anions in blood or urine
(positively charged ions) and anions (negatively charged ions) in serum, plasma, or urine. The magnitude of this difference (i.e., "gap") in the serum is
Anion_gap
Chemical compound
target various parts of the complicated renin-angiotensin system were developed to increase knowledge of the renin-angiotensin system and aid the development
EMA401
Root of Glycyrrhiza glabra
and hormonal regulation. Some of these activities may include raised aldosterone levels, decline of the renin–angiotensin system and increased levels
Liquorice
Chemical compound
stroke volume due to plasma volume expansion, and potential dysregulation of glucocorticoid receptors or 11β-hydroxylase enzyme activity. These mechanisms
11-Deoxycortisol
Hormone used in regulating the cardiovascular system
the activity of the renin-angiotensin-aldosterone system (RAAS), which regulates blood pressure. Studies have shown that ANP can suppress renin secretion
Natriuretic_peptide
Beta blocker medication
other classes of medicines such as diuretics, calcium-channel blockers, and renin-angiotensin system inhibitors. Most of these findings come from one type
Atenolol
Protein-coding gene in humans
cerebrospinal fluid, seminal plasma, and retroplacental plasma in low levels. In healthy adults, cDPP3 is present in plasma at a median concentration of
DPP3
Hormone and medication
Grahame-Smith DG (August 1979). "Plasma adrenaline and noradrenaline concentrations and dopamine-beta-hydroxylase activity in myocardial infarction with
Adrenaline
Diuretics that do not cause potassium loss
causes water retention. When the kidneys detect low blood pressure, the renin–angiotensin–aldosterone system (RAAS) is activated and eventually, aldosterone
Potassium-sparing_diuretic
Class of compounds
thus opposing blood vessel contraction. Alpha-1 blockers have no effect on renin release or cardio output. Alpha-1 blocker, blocks alpha receptors and it
Alpha-1_blocker
Medical condition
in the blood, alkalosis, normal to low blood pressures, and elevated plasma renin and aldosterone. Numerous causes of this syndrome probably exist. Diagnostic
Bartter_syndrome
Paired organ in the urinary system of mammals
and urine formation is a result of these processes. The kidneys produce renin and erythropoietin hormones, and are involved in the conversion of vitamin
Mammalian_kidney
Human protein
blood vessels, a result of arterial hypertension and activation of the renin–angiotensin system. Annonacinone is a naturally occurring PAI-1 inhibitor
Plasminogen activator inhibitor-1
Plasminogen_activator_inhibitor-1
Dicarboxylic acid
mitochondrial concentrations are approximately ~0.5 mM while plasma concentration are only 2–20 μM. The activity of succinate dehydrogenase (SDH), which interconverts
Succinic_acid
Drug class
as dilatation of bronchioles and pupils, increased heart rate and kidney renin secretion, constricted blood vessels and inhibited peristalsis. Norepinephrine
Selective norepinephrine reuptake inhibitor
Selective_norepinephrine_reuptake_inhibitor
Protein-coding gene in the species Homo sapiens
in humans is encoded by the ATP6AP2 gene. The renin receptor binds renin and prorenin. Binding of renin to this receptor induces the conversion of angiotensinogen
Renin_receptor
Protein-coding gene in the species Homo sapiens
shortened and starts with asparagine; the latter form constitutes about 70% of plasma α2AP and is more efficiently cross-linked to fibrin. The C-terminal region
Alpha_2-antiplasmin
Involuntary non-striated muscle
tubuloglomerular regulation of glomerular filtration rate. Renin in turn activates the renin–angiotensin system to regulate blood pressure. The mechanism
Smooth_muscle
Pharmacology of a New Angiotensin Peptide
Alamandine is a member of renin-angiotensin system (RAS) with cardiovascular functions that are protective and opposing to the classical axis. Alamandine
Alamandine
Mammalian hormone released from the pituitary gland
considered to be increased and sodium is excreted to lower blood pressure. Renin-angiotensin system: When the blood flow through the juxtaglomerular apparatus
Vasopressin
Pressure exerted by circulating blood upon the walls of arteries
dependent on autonomic nervous system responses and the renin–angiotensin system, changes in plasma osmolarity may also be important. In the longer-term
Blood_pressure
Primary female sex hormone
There are three major endogenous estrogens that have estrogenic hormonal activity: estrone (E1), estradiol (E2), and estriol (E3). Estradiol, an estrane
Estrogen
Glands of the endocrine system that secrete hormones to blood
pregnancy—estrogen, progesterone, and others); the kidneys (erythropoietin and renin); the thymus; skin (cholecalciferol); and adipose tissue (leptin and resistin)
Endocrine_gland
Peptide hormone and neuropeptide
continues until the triggering activity ceases. A similar process takes place during lactation and during sexual activity. Oxytocin is derived by enzymatic
Oxytocin
Part of the autonomic nervous system that stimulates fight-or-flight responses
associated with sympathetic dysfunction, which include reduced levels of plasma norepinephrine levels, sensitivity of the peripheral adrenergic receptors
Sympathetic_nervous_system
Drug that inhibits activity of immune system
immunosuppressants and antirejection medications, are drugs that inhibit or prevent the activity of the immune system. Immunosuppressive drugs can be classified into five
Immunosuppressive_drug
Protein-coding gene in the species Homo sapiens
"Olfactory receptor responding to gut microbiota-derived signals plays a role in renin secretion and blood pressure regulation". Proceedings of the National Academy
OR51E2
Anti-hypertension medication
angina pectoris or myocardial infarction. Hydralazine may also increase plasma renin concentration, resulting in fluid retention. To prevent these undesirable
Hydralazine
Vertebrate natural glucocorticoid hormone
to inhibit IgE. Cortisol increases glomerular filtration rate, and renal plasma flow from the kidneys thus increasing phosphate excretion, as well as increasing
Cortisol
PLASMA RENIN-ACTIVITY
PLASMA RENIN-ACTIVITY
Female
Hindi/Indian
(पदà¥à¤®) Hindi unisex name PADMA means "lotus flower."
Boy/Male
Biblical
Good-will, messenger.
Boy/Male
Hindu, Indian, Tamil
A Little Cape; Cloak
Girl/Female
Greek
Peace. An early Christian martyr, and later borne by several Byzantine empresses.
Boy/Male
Hindu
Female
Spanish
Spanish name PALOMA means "dove, pigeon."
Surname or Lastname
English
English : presumably a variant of Reddan or Reading.
Boy/Male
Muslim
Pasha. A Title.
Female
English
English pet form of Latin Irene, RENIE means "peace."
Boy/Male
Gujarati, Hindu, Indian, Kannada, Tamil
Lord of Love; Victory; Wonder
Female
Hebrew
Variant spelling of Hebrew Bosma, BASMA means perfumed."
Male
Welsh
Welsh form of Celtic Brennus, BRENIN means "king."
Boy/Male
Norse
A mythical blacksmith.
Male
Russian
(Паша) Russian pet form of Czech/Russian Pavel, PASHA means "small."
Boy/Male
Hindu
Lover
Boy/Male
Hindu
Victory
Male
German
Short form of German names beginning with Rein-, REIN means "wise."
Boy/Male
Hindu
Male
Native American
Native American Dakota name MAZA BLASKA means "flat iron."
Boy/Male
Latin
Blessed.
PLASMA RENIN-ACTIVITY
PLASMA RENIN-ACTIVITY
PLASMA RENIN-ACTIVITY
PLASMA RENIN-ACTIVITY
PLASMA RENIN-ACTIVITY
PLASMA RENIN-ACTIVITY
PLASMA RENIN-ACTIVITY
n.
A mixture of starch and glycerin, used as a substitute for ointments.
n.
A dark discoloration of the skin, usually local; as, Addison's melasma, or Addison's disease.
v. t.
To govern or direct with the reins; as, to rein a horse one way or another.
n.
An albuminous body present in dead muscle, being formed in the process of coagulation which takes place in rigor mortis; the clot formed in the coagulation of muscle plasma. See Muscle plasma, under Plasma.
n.
Hyaline plasma contained in the nucleus of vegetable cells.
n.
A proteid body, separated by some physiologists from blood plasma. It is probably identical with fibrinogen.
a.
Of or pertaining to plasma; having the character of plasma; containing, or conveying, plasma.
n.
Miasma.
n.
See Llama.
pl.
of Miasma
v. t.
To splash or sprinkle with coloring matter; as, to plash a wall in imitation of granite.
n.
Unorganized material; elementary matter.
n.
The viscous material of an animal or vegetable cell, out of which the various tissues are formed by a process of differentiation; protoplasm.
a.
Of, pertaining to, or connected with, plasma; plasmatic.
n.
Alt. of Phasma
n.
A variety of quartz, of a color between grass green and leek green, which is found associated with common chalcedony. It was much esteemed by the ancients for making engraved ornaments.
pl.
of Palama
n.
Any one of a class of yellowish brown solid inflammable substances, of vegetable origin, which are nonconductors of electricity, have a vitreous fracture, and are soluble in ether, alcohol, and essential oils, but not in water; specif., pine resin (see Rosin).
n.
Same as Plasma.
v. t.
To cut partly, or to bend and intertwine the branches of; as, to plash a hedge.