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Use of pharmaceuticals for conditions different from that for which they were approved
Off-label use is the use of pharmaceutical drugs for an unapproved indication or in an unapproved age group, dosage, or route of administration. Both prescription
Off-label_use
Pharmaceutical drugs become known for off-label use when publications begin discussing how they can be used for off-label treatment of medical conditions.
List of drugs known for off-label use
List_of_drugs_known_for_off-label_use
Marketing of off-label use is advertising the use of drugs for purposes not approved by the regional government. The practice is often illegal and has
Marketing_of_off-label_use
their products for uses not approved by the Food and Drug Administration (FDA), and corporations that market drugs for off-label indications may be subject
List of off-label promotion pharmaceutical settlements
List_of_off-label_promotion_pharmaceutical_settlements
Peptide hormone that stimulates growth
drugs for off-label use (with concern of ethics violations) have made strong statements about whether doctors can prescribe HGH off-label: "Unlike other
Growth_hormone
Material affixed to a container or article with printed information
most often affixed to packaging and containers using an adhesive, or sewing when affixed to clothing. Labels contain printed information or symbols about
Label
Gamma-aminobutyric acid analog
gabapentin has seen increased use, particularly in the elderly. There is concern regarding gabapentin's off-label use due to the lack of strong scientific
Gabapentin
Cough suppressant and dissociative drug
dextromethorphan can still be sold over the counter. It may be used in generic labels and store brands, Benylin DM, Mucinex DM, Camydex-20 tablets, Komix
Dextromethorphan
Tetracycline-class antibiotic
(collections of lymph fluid outside of lymphatic vessels). Doxycycline is used off-label in the treatment of transthyretin amyloidosis (ATTR). In combination
Doxycycline
Outcome that is secondary to the one intended
usually used for a specific effect may be used specifically because of a beneficial side-effect; this is termed "off-label use" until such use is approved
Side_effect
Valid reason to use a certain test, medication, procedure, or surgery
line drug. Off-label Off-label indications are drugs that are used for medical indications that have not been approved by the FDA. Off-label indications
Indication_(medicine)
Nonsteroidal anti-inflammatory drug (NSAID)
many other countries. Meloxicam is used in veterinary medicine mainly to treat dogs, but also sees off-label use in other animals such as cattle and
Meloxicam
American physician and convicted felon (born 1953)
be used off-label in a responsible manner which is medically appropriate for their patient but different from the intended use the indicated use for
Conrad_Murray
Group of growth factor proteins
for some uses. rhBMP-2 causes more overgrown bone than any other BMPs and is widely used off-label. BMPs for clinical use are produced using recombinant
Bone_morphogenetic_protein
Anticonvulsant and analgesic medication
variety of off-label uses, including for pain management and treatment of mental health disorders. Lacosamide and other AEDs have been used off-label in the
Lacosamide
American physician
gained attention during the COVID-19 pandemic for advocating widespread off-label use of ineffective drug treatments for COVID-19, as president and co-founder
Pierre_Kory
Brand associated with music and music videos
music labels A record label or record company is a brand or trademark of music recordings and music videos, or the company that owns it. A record label can
Record_label
easily steamed off, recent automatic bottling and labeling processes at wineries have led to the use of stronger glues. Removing these labels is often difficult
Wine_label
Class of medications
and this is ascribed to off-label use for many other unapproved disorders. Besides the above uses antipsychotics may be used for obsessive–compulsive
Antipsychotic
Medication used to treat malaria and babesiosis
used only when artemisinins are not available. Quinine is also used to treat lupus and arthritis. Quinine was frequently prescribed as an off-label treatment
Quinine
Wakefulness-promoting medication
during pregnancy due to increased risk of birth defects. Modafinil is used off-label as a cognitive enhancer by students and professionals seeking improved
Modafinil
Third-generation topical retinoid
third-generation topical retinoid primarily used in the treatment of mild-moderate acne, and is also used off-label to treat keratosis pilaris as well as other
Adapalene
Irish tax-registered pharmaceutical corporation
guilty to felony charges related to its illegal marketing of Xyrem for off-label use. The company is also a member of the Pharmaceutical Research and Manufacturers
Jazz_Pharmaceuticals
Pharmaceutical drug
to the endothelium and blockage of the vessels. Verteporfin is also used off-label for the treatment of central serous retinopathy. Verteporfin is usually
Verteporfin
American pharmaceutical company
our work with Zyprexa in this same child-adolescent population" for off-label use. In January 2020, lawyer James Gottstein published a book titled The
Eli_Lilly_and_Company
Drug whose use induces sleep
PMID 30137790. It is also prescribed off-label for migraine headaches, insomnia, and as an anticonvulsant. [...] Off-label Use [...] Refractory insomnia in spastic
Hypnotic
US law
about unapproved uses of drugs and medical devices. The act allows a firm to circulate peer-reviewed journal articles about an off-label indication of its
Food and Drug Administration Modernization Act of 1997
Food_and_Drug_Administration_Modernization_Act_of_1997
Medication legally requiring a medical prescription before it can be dispensed
Physicians may legally prescribe drugs for uses other than those specified in the FDA approval, known as off-label use.[citation needed] Drug companies, however
Prescription_drug
Atypical antipsychotic medication
typically used off-label in the treatment of insomnia. These safety concerns at low doses are corroborated by Danish observational studies that showed use of
Quetiapine
Birth control measures taken after sexual intercourse
intercourse. The U.S. Food and Drug Administration (FDA) approved this off-label use of certain brands of regular combined oral contraceptive pills in 1997
Emergency_contraception
American multinational pharmaceutical and biotechnology corporation
promote gabapentin. Within five years, the drug was being widely used for off-label uses such as treatment of pain and psychiatric conditions. Warner–Lambert
Pfizer
Uses of drug ivermectin during the COVID-19 pandemic
efficacy and advice to the contrary, some governments have allowed its off-label use for the prevention and treatment of COVID‑19. Countries that have granted
Ivermectin during the COVID-19 pandemic
Ivermectin_during_the_COVID-19_pandemic
Scientific article
The company relied on the JAACAP article to promote paroxetine for off-label use in teenagers. In 2003 Britain's Medicines and Healthcare products Regulatory
Study_329
Muscle relaxant medication
baclofen and diazepam. Tizanidine may be used off-label in the treatment of insomnia and for certain other uses. Side effects include dizziness, drowsiness
Tizanidine
Anticonvulsant medication
which is used in the treatment of epilepsy. It is also used off-label in the treatment of insomnia and anxiety disorders. However, off-label use is discouraged
Tiagabine
Controversies regarding the use of human growth hormone
marketing drugs for off-label use (which is clearly illegal) have made strong statements about whether doctors can prescribe HGH off-label: "Unlike other prescription
HGH_controversies
Pharmaceutical drug
Despite this, it may still be used in some off-label contexts or obtained through compounding pharmacies. Sermorelin was used to treat children with growth
Sermorelin
off-label promotion, and inadequate manufacturing practices. With respect to off-label promotion, specifically, a federal court recognized off-label promotion
List of largest pharmaceutical settlements
List_of_largest_pharmaceutical_settlements
Substance used to diagnose, cure, treat, or prevent disease
pharmacy technician. Doctors may also prescribe prescription drugs for off-label use – purposes which the drugs were not originally approved for by the regulatory
Medication
Digital radio standard
Evoke in 2002 (which used an IC made by Frontier Silicon, a company that would power many DAB tuners in the future), helped to take off DAB to consumers for
Digital_Audio_Broadcasting
Franklin v. Parke-Davis trial for False Claims Act violations relating to off-label use of gabapentin. There were 24 original grant recipients. Oregon State
Consumer & Prescriber Grant Program
Consumer_&_Prescriber_Grant_Program
Chemical compound
this product in a manner inconsistent with its labeling." "Off-label" uses and other uses not specifically targeted at problem insects are illegal, dangerous
Methomyl
Lists of the main pharmaceutical drugs
antidepressants Lists of investigational drugs List of drugs known for off-label use List of psychiatric medications List of psychiatric medications by condition
Lists_of_drugs
Network routing scheme based on labels identifying paths
receiving a labeled packet that is destined to exit the MPLS domain, the LER strips off the label and forwards the resulting IP packet using normal IP forwarding
Multiprotocol_Label_Switching
1979 studio album by Michael Jackson
because of Off the Wall [and] "Don't Stop 'Til You Get Enough"...I always use Michael [Jackson] as, first and foremost, a vocal inspiration, and Off the Wall
Off_the_Wall
Health-care communication from a physician to a pharmacist
benefit-harm ratio falls with marketing Medicines reconciliation Off-label use – Use of pharmaceuticals for conditions different from that for which they
Medical_prescription
Drug class
uricosuric action, their other significant pharmacological actions in off-label use as a uricosuric requires careful assessment of the patient to achieve
Uricosuric
prescription of mifepristone (which is commonly used for medication abortion) for any off-label use. Due to November 2023 Ohio Issue 1, abortions up
Abortion_in_Ohio
Warning label
film rating system be enacted. The RIAA alternatively suggested using a warning label reading "Parental Guidance: Explicit Lyrics", and after continued
Parental_Advisory
Effect of drug opposite to expectation
naltrexone is believed to have an anti-inflammatory effect. This is an off-label use and not widely accepted by the medical and scientific community. Diphenhydramine
Paradoxical_reaction
1996 lawsuit
motion for summary judgment, the court for the first time recognized off-label promotion of drugs could cause Medicaid to pay for prescriptions that
Franklin_v._Parke-Davis
Therapeutic use of prescribed ketamine
treatment for depression, substance use dependence, and more. Thus, soon after discovery, ketamine has been used as an off-label medication for a diverse group
Ketamine-assisted psychotherapy
Ketamine-assisted_psychotherapy
Canadian record label
Canadian independent record label, founded in 2009 by rapper Drake, producer 40, and manager Oliver El-Khatib. The label operated as a subsidiary of Warner
OVO_Sound
Medication
challenged the FDA's authority to limit its ability to market the drug for off-label use and won its case on appeal in 2015, changing the way the FDA regulates
Ethyl_eicosapentaenoic_acid
Breast cancer drug
same rate of miscarriages. The use of letrozole is typically off-label, and some countries may not allow off-label use. India banned the usage of letrozole
Letrozole
Medication primarily used to treat severe acne
moderate acne that is unresponsive to antibiotics. Isotretinoin is used off-label to treat basal cell carcinoma and squamous cell carcinoma, although
Isotretinoin
Proposed but ineffective treatment for methamphetamine addiction
therapy. While the individual drugs had been approved by the FDA, their off-label use for addiction treatment has not. Gabasync was marketed by Hythiam, Inc
Gabasync
the most common being studying. Since amphetamine use is illicit in most countries, the off-label use by students is often regarded as a major issue by
History and culture of substituted amphetamines
History_and_culture_of_substituted_amphetamines
Drugs used to suppress premature births
and Drug Administration (FDA) for use in stopping uterine contractions in preterm labor, instead being used off-label. According to a 2022 Cochrane review
Tocolytic
Commodity trade outside of original producer's distribution channel
pharmaceuticals than Americans do. A related concept is off-label use. Drugs are generally authorized for particular uses, but such authorization generally only prohibits
Grey_market
American microbiologist
lawsuit exposing their illegal promotion of Neurontin (gabapentin) for off-label uses. Franklin's suit, filed on behalf of the citizens of the United States
David_Franklin_(scientist)
1973 single by James Brown
for Slaughter's Big Rip-Off and also as a single in 1973. Both forms were distributed under the German-British record label Polydor Records, who had
Sexy,_Sexy,_Sexy
Medication used to treat dyskinesia
arisen. A 2017 systematic review of off-label augmentation for treatment of unipolar depression found two open-label studies of amantadine for augmenting
Amantadine
American political organization
No Labels is an American political organization whose stated mission is to support bipartisanship and unity through what it calls the "commonsense majority"
No_Labels
Act of the Parliament of the United Kingdom
Ethics and Practice. The act was introduced following problems with the off-label use of thalidomide. The act established the forerunner to the current Commission
Medicines_Act_1968
Use of multiple psychoactive substances
use or poly drug use refers to the use of combined psychoactive substances. Polysubstance use may be used for entheogenic, recreational, or off-label
Polysubstance_use
1974 single by Pilot
for people with type 2 diabetes, but which became popular for its off-label use as a weight-loss drug. David Paton was asked to return to Abbey Road Studios
Magic_(Pilot_song)
Medical condition
L; Suttorp, MJ; Ewing, BA; Motala, A; Perry, T (September 2011). "Off-Label Use of Atypical Antipsychotics: An Update [Internet]". Agency for Healthcare
Substance_abuse
Nonsteroidal anti-inflammatory drug
rheumatoid arthritis, and primary dysmenorrhea. Valdecoxib was also used off-label for controlling acute pain and various types of surgical pain. On April
Valdecoxib
Pharmaceutical prescribing reference guide
are not included in the guide, nor does it provide information about off-label use. Haymarket Group also publishes trade magazines. Several one-day clinical
Monthly Index of Medical Specialities
Monthly_Index_of_Medical_Specialities
Energy consumption labelling scheme
since 2010, a new type of label exists that makes use of pictograms rather than words, to allow manufacturers to use a single label for products sold in different
European_Union_energy_label
Atypical antipsychotic medication
atypical antipsychotic primarily used to treat schizophrenia and bipolar disorder. It is also sometimes used off-label in cancer patients for treatment
Olanzapine
Medical research using human test subjects
humans Off-label use – the practice of prescribing a drug for an indication for which the drug has not been approved Orphan drug – a drug used to treat
Outline_of_clinical_research
Chemical compound
carton label. In the 1980s, off-label use of the Yuzpe regimen of certain regular combined oral contraceptive pills superseded off-label use of DES as
Diethylstilbestrol
Concept in United States copyright law
Supreme Court labeled the fourth factor "the single most important element of fair use" and it has enjoyed some level of primacy in fair use analyses ever
Fair_use
Medication
States. The main uses of mepacrine are as an antiprotozoal, antirheumatic, and an intrapleural sclerosing agent. Mepacrine finds off-label use as a primary
Mepacrine
Medical research using human test subjects
preclinical studies or other supporting evidence, or case studies of off label use are submitted to the FDA in support of an Investigational New Drug application
Clinical_research
American fashion label
The Row is an American luxury fashion label established by Mary-Kate and Ashley Olsen in 2006 in New York City. The Row produces ready-to-wear clothing
The_Row_(fashion_label)
Corticosteroid medication
disease, and neoplasia is often considered off-label use. Many drugs are commonly prescribed for off-label use in veterinary medicine." Studies in ruminating
Prednisolone
Drug of the fibrate class, mainly used to reduce cholesterol levels
neuropathy. Fenofibrate has an off-label use as an added therapy of high blood uric acid levels in people who have gout. It is used in addition to diet to reduce
Fenofibrate
Medication used to treat epilepsy and migraine
includes treatment for generalized or focal seizures. It has also been used off-label for alcohol dependence and essential tremor. Common side effects include
Topiramate
Dutch healthcare company
medicines can be achieved via clinical trials, expanded access and off-label use. myTomorrows was founded in 2012 by Ronald Brus, former CEO of the biotechnology
MyTomorrows
Topics referred to by the same term
Black Label, a South Korean record label Carling Black Label, a Canadian beer brand DC Black Label, a DC Comics label Johnnie Walker Black Label, a Scotch
Black_Label
British television baking competition
The Great British Bake Off (often abbreviated to Bake Off or GBBO) is a British television baking competition, produced by Love Productions, in which a
The_Great_British_Bake_Off
United States federal anti-fraud law
to settle allegations of violating the False Claims Act by promoting off label use of its products in the case United States ex rel. Kirk v. CareFusion
False_Claims_Act_of_1863
Class of pharmaceutical drugs
disorder, persecutory delusion and obsessive-compulsive disorder (an off-label use). In dementia, they should only be considered after other treatments
Atypical_antipsychotic
Appetite suppressant
Sanorex, is an appetite suppressant which is used in the short-term treatment of obesity. It is also used off-label in the treatment of narcolepsy and cataplexy
Mazindol
Chemical compound
This is its only FDA, MHRA and TGA-labelled indication. However, pentoxifylline is also recommended for off-label use as an adjunct to compression bandaging
Pentoxifylline
Chemical compound which aids breathing
through publicized stories of use by celebrities such as Victoria Beckham, Britney Spears, and Lindsay Lohan, for its off-label use as a weight-loss drug similar
Clenbuterol
Principle of medical research in clinical trials
medical community… about the preferred treatment.” This applies also for off-label treatments performed before or during their required clinical trials.
Clinical_equipoise
Antispasmodic agent
helpful for the treatment of anxiety, but this is an off-label use. This medicine should not be used for people who have an obstructive GI or urinary condition
Dicycloverine
spray FDA label" (PDF). Food and Drug Administration. 5 March 2019. Retrieved 6 March 2019. Zhang MW, Harris KM, Ho RC (2016). "Is off-label repeat prescription
List_of_antidepressants
Discontinued medication
obesity, a treatment for narcolepsy, parkinsonism, alcoholism, and some off-label uses, Desbutal had a high potential for abuse and dependence, consequently
Desbutal
British record label active 1909–1993
the retail business it had previously spun-off in 1998. His Master's Voice was founded as a classical label. From December 1899, the predecessor to EMI
His Master's Voice (British record label)
His_Master's_Voice_(British_record_label)
2026 studio album by J. Cole
The Fall-Off is the seventh and final studio album by American rapper J. Cole. Released through Cole World, Dreamville Records, and Interscope Records
The_Fall-Off
Tropane alkaloid
industry in Queensland. A separate historic, apparent, but unsubstantiated off-label use of hysoscyamine was in the treatment of sexually transmitted infections
Hyoscyamine
British record label
Mortal Coil. In 1987, the label scored an international hit with the dance music single "Pump Up the Volume" by the one-off project M|A|R|R|S. 4AD continued
4AD
involving bone marrow failure, including aplastic anemia and has additional off-label uses. Antithymocyte globulin (ATG) was originally developed as one of various
Thymoglobulin
polysubstance combinations that are entheogenic, recreational, or off-label indicated use of pharmaceuticals. For example, the over-the-counter motion sickness
List_of_drug_combinations
Medical intervention
outside of the possible early detection of testicular cancer, other "off label" uses of TSEs include detection of indirect inguinal hernias, varicocele
Testicular_self-examination
OFF LABEL-USE
OFF LABEL-USE
Surname or Lastname
English
English : variant of Rolfe.North German : variant of Ruoff.
Surname or Lastname
Welsh
Welsh : nickname for a red-haired person (see Gough).English (of Cornish and Breton origin) : occupational name from Cornish and Breton goff ‘smith’ (cognate with Gaelic gobha). The surname is common in East Anglia, where it is of Breton origin, introduced by followers of William the Conqueror.Irish : reduced form of McGoff.Edward Goffe was a farmer in Cambridge MA whose house was acquired by Harvard College some time before 1654 and used as a dormitory, known as Goffe’s College.
Girl/Female
Latin American English
Beautiful, loving, lovable.Amabel was used frequently during the Middle Ages and briefly in the...
Male
Greek
(á¼Î²ÎµÎ») Greek form of Hebrew Hebel ("breath, breathing"), HABEL means "vanity," i.e. "transitory." In the bible, this is the name of the second son of Adam and Eve who was killed by his jealous brother Cain.
Girl/Female
Biblical, British, English, French, Greek
Confusion; Mixture
Biblical
confusion; mixture,confusion,gate of God
Boy/Male
Biblical American Hebrew
Vanity, breath, vapor. Also a city, mourning'.
Surname or Lastname
English
English : from Old French boeuf ‘bull’, a nickname for a powerfully built man. In some cases it may have been originally a metonymic occupational name for a herdsman. Compare Bouvier.German (Böff) : from the short form of a Germanic personal name with bod- (Old Saxon bodo ‘messenger’), as in Bodo.
Biblical
mourning to the house of Maachah,meadow of the house of Maachah,also called ABEL-MAIM
Female
English
Medieval short form of English Amabel, MABEL means "lovable."Â
Boy/Male
Hindu, Indian
Different
Girl/Female
Latin
Lovable.
Girl/Female
Christian & English(British/American/Australian)
Amiable
Girl/Female
American, British, Christian, English, Jamaican, Latin, Swedish
Lovable
Girl/Female
British, English, Netherlands
Super
Boy/Male
Anglo, British, English
Name of a King
Male
Hebrew
(לָ×ֵל) Hebrew name LAEL means "belonging to God" or "by God." In the bible, this is the name of a leader of the Gershon family.
Boy/Male
Indian
Healthy, Vanity, Breath, Breathing
Girl/Female
Biblical Hebrew
To God, to the mighty.
Male
English
 In the bible, this is the name of the second son of Adam and Eve who was killed by his jealous brother Cain. Anglicized form of Greek Habel, ABEL means "vanity," i.e. "transitory." Anglicized form of Hebrew Hebel, meaning "breath, breathing."
OFF LABEL-USE
OFF LABEL-USE
Girl/Female
Muslim
Girl/Female
Indian
Soul
Girl/Female
Indian, Tamil
God Pray
Girl/Female
Assamese, Bengali, Celebrity, Gujarati, Hindu, Indian, Kannada, Malayalam, Marathi, Sanskrit, Tamil, Telugu
Victorious Goddess Durga
Boy/Male
Hindu
The Moon
Boy/Male
German
Dominant Ruler
Boy/Male
Muslim
Responsible Man
Girl/Female
Arabic, Australian, Indian, Muslim, Parsi, Turkish
Heart-ravishing
Girl/Female
Biblical American English Latin
Iniquity.
Female
English
Pet form of English Josephine, JOSIE means "(God) shall add (another son)."Â
OFF LABEL-USE
OFF LABEL-USE
OFF LABEL-USE
OFF LABEL-USE
OFF LABEL-USE
n.
In mediaeval art, the representation of a band or scroll containing an inscription.
imp. & p. p.
of Libel
imp. & p. p.
of Label
n.
Confused; Babel-like.
v.
A label to show the character or price of goods.
n.
One who labels.
n.
A slip of silk, paper, parchment, etc., affixed to anything, usually by an inscription, the contents, ownership, destination, etc.; as, the label of a bottle or a package.
p. pr. & vb. n.
of Label
p. pr. & vb. n.
of Libel
v. t.
To affix in or on a label.
v. t.
To proceed against by filing a libel, particularly against a ship or goods.
n.
A brass rule with sights, formerly used, in connection with a circumferentor, to take altitudes.
v. t.
To libel mutually.
n.
A writing annexed by way of addition, as a codicil added to a will.
v. t.
To affix a label to; to mark with a name, etc.; as, to label a bottle or a package.
n.
A barrulet, or, rarely, a bendlet, with pendants, or points, usually three, especially used as a mark of cadency to distinguish an eldest or only son while his father is still living.