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Subtype of leukocytes
Monocytes are a type of leukocyte or white blood cell. They are the largest type of leukocyte in the blood and can differentiate into macrophages and
Monocyte
Medical diagnostic method
Monocyte distribution width (MDW) is a cytometry-based parameter that measures the range of variation of monocytes. If the parameter is available, it is
Monocyte_distribution_width
Protein found in humans
The chemokine (C-C motif) ligand 2 (CCL2) is also referred to as monocyte chemoattractant protein 1 (MCP1) and small inducible cytokine A2. CCL2 is a small
CCL2
Type of cells of the immunological system
(monocytes, and lymphocytes (T cells and B cells)). Myeloid cells (myelocytes) include neutrophils, eosinophils, mast cells, basophils, and monocytes.
White_blood_cell
Laboratory test for clinically significant alloantibodies
The monocyte monolayer assay (MMA) is used to determine the clinical significance of alloantibodies produced by blood transfusion recipients. The assay
Monocyte_monolayer_assay
Musical artist
His next two albums ("Monocyte", "Monocyte: The Lapis Coil") were also released under mentioned label, both in 2012. "Monocyte" was created as a concept
Menton_J._Matthews_III
Mammalian protein found in humans
motif) ligand 7 (CCL7) is a small cytokine that was previously called monocyte-chemotactic protein 3 (MCP3). CCL7 is a small protein that belongs to the
CCL7
Medical condition
of monocytes in the bone marrow. There is an overproduction of monocytes that the body does not need in the periphery. These overproduced monocytes interfere
Acute_monocytic_leukemia
Cell that matures into a monocyte
process of hematopoiesis. They are the first developmental stage in the monocyte series leading to a macrophage. Their myeloid cell fate is induced by the
Monoblast
Connective tissue in the spleen
population of monocytes and macrophages. These cords contain half of the mouse body's monocytes as a reserve so that, after tissue injury, these monocytes can move
Cords_of_Billroth
Formation of blood cellular components
Cells of the myeloid lineage, which include granulocytes, megakaryocytes, monocytes, and macrophages, are derived from common myeloid progenitors, and are
Haematopoiesis
Part of the immune system
cells located in reticular connective tissue. The cells are primarily monocytes and macrophages, and they accumulate in lymph nodes and the spleen. The
Mononuclear_phagocyte_system
Protein-coding gene in the species Homo sapiens
gene. The protein is also historically known as serine esterase 1 (SES1), monocyte esterase and cholesterol ester hydrolase (CEH). Three transcript variants
Carboxylesterase_1
Mammalian protein found in humans
immune reaction in the innate immune system response. IL-8, also known as monocyte-derived neutrophil chemotactic factor (MDNCF), has two primary functions
Interleukin_8
Topics referred to by the same term
Marketplace, a former online music market CFU-GEMM, granulocyte-erythrocyte-monocyte-megakaryocyte colony forming unit Gem (disambiguation) This disambiguation
GEMM
One of the two types of white blood cells
several reasons. First, monocytes contain granules, which tend to be fine and weakly stained (see monocyte entry). Second, monocytes and the granulocytes
Agranulocyte
Mammalian protein found in Homo sapiens
produce granulocytes (neutrophils, eosinophils, and basophils) and monocytes. Monocytes exit the circulation and migrate into tissue, whereupon they mature
Granulocyte-macrophage colony-stimulating factor
Granulocyte-macrophage_colony-stimulating_factor
Type of cell
the monocyte lineage, situated between monoblasts and monocytes, and plays a crucial role in immune function and hematopoiesis. The term monocyte specifically
Promonocyte
American immunologist
School of Medicine. During her postdoctoral work, Randolph characterized monocyte differentiation to dendritic cells and macrophages and made advances in
Gwendalyn_J._Randolph
Chemical used for the detection and quantification of bacterial endotoxins
amebocyte lysate test. The monocyte activation test (MAT) is another proposed method to test for endotoxins based on monocytes in human blood. It measures
Limulus_amebocyte_lysate
Protein-coding gene in the species Homo sapiens
or ov-serpins (ovalbumin related serpins) founded by ovalbumin. MNEI (monocyte/neutrophil elastase inhibitor) is the mouse orthologue of human SerpinB1
SERPINB1
Medical condition
chaffeensis. This bacterium is an obligate intracellular pathogen affecting monocytes and macrophages. The most common symptoms are fever, headache, malaise
Human monocytotropic ehrlichiosis
Human_monocytotropic_ehrlichiosis
Type of cytokines secreted by adipose tissue
Members include: Leptin Adiponectin Apelin chemerin interleukin-6 (IL-6) monocyte chemotactic protein-1 (MCP-1) plasminogen activator inhibitor-1 (PAI-1)
Adipokine
Tissue of bone marrow
cells are blood cells that arise from a progenitor cell for granulocytes, monocytes, erythrocytes, or platelets (the common myeloid progenitor, that is, CMP
Myeloid_tissue
Increase in the number of monocytes circulating in the blood
Monocytosis is an increase in the number of monocytes circulating in the blood. Monocytes are white blood cells that give rise to macrophages and dendritic
Monocytosis
Interruption of cardiac blood supply
577–9. ISBN 978-0-7020-3085-7. Woollard KJ, Geissmann F (February 2010). "Monocytes in atherosclerosis: subsets and functions". Nature Reviews. Cardiology
Myocardial_infarction
Abnormal white blood cell inclusion
blue-green cytoplasmic inclusions found in neutrophils and occasionally in monocytes. They appear brightly coloured and refractile when stained with Wright-Giemsa
Critical_green_inclusion
Protein-coding gene in the species Homo sapiens
609509) signals. Expression of IL31RA and OSMR mRNA is induced in activated monocytes, and both mRNAs are constitutively expressed in epithelial cells (Dillon
IL31RA
Protein in human genes
Monocyte to macrophage differentiation factor also known as PAQR11 is a protein that in humans is encoded by the MMD gene. It is a member of the progestin
Monocyte to macrophage differentiation factor
Monocyte_to_macrophage_differentiation_factor
Protein-coding gene in the species Homo sapiens
1994). "Characterization of a novel tumor-derived cytokine. Endothelial-monocyte activating polypeptide II". J Biol Chem. 269 (40): 25106–19. doi:10
SCYE1
Protein-coding gene in the species Homo sapiens
node, bone marrow, colon, and lungs. Soluble SIGLEC-1 is a biomarker of monocyte-macrophage activation in systemic lupus erythematosus (SLE) and other autoimmune
Sialoadhesin
Protein found in humans
affinity - for hemoglobin alone. It also is a marker of cells from the monocyte/macrophage lineage. CD163 functions as innate immune sensor for gram-positive
CD163
Mammalian protein found in mice
chemokine family that has been described in mice. It is also known as monocyte chemotactic protein 5 (MCP-5) and, due to its similarity with the human
CCL12
Medical condition
process known as haematopoiesis. In CMML, there are increased numbers of monocytes and immature blood cells (blasts) in the peripheral blood and bone marrow
Chronic myelomonocytic leukemia
Chronic_myelomonocytic_leukemia
American cardiovascular scientist
Described monocyte recruitment during myocardial infarction and showed a role for a splenic monocyte reservoir as a source of monocytes after myocardial
Filip_Swirski
Cell type
(Colony Forming Unit-Granulocyte/Macrophage), also known as Granulocyte-Monocyte Progenitor (GMP), is a colony forming unit. It is derived from CFU-GEMM
CFU-GM
HIV entry inhibitor discovered in 1986
infected monocyte reservoir to undetectable levels in most of the patients. Elimination of viral reservoirs, such as the persistently infected monocytes or
Peptide_T
Protein-coding gene in humans
innate immune response. Expression is found on myeloid dendritic cells, monocytes, macrophages and B cells. Alternate transcriptional splice variants, encoding
CLEC7A
glomerulus adrenal gland spleen fundus olfactory zone of nasal mucosa monocyte body of pancreas islet of Langerhans n/a More reference expression data
MIR200C
Non-coding RNA in the species Homo sapiens
Human Mouse (ortholog) Top expressed in sural nerve blood body of pancreas monocyte left ventricle stomach body of stomach fundus endometrium fallopian tube
MicroRNA_148a
Medical condition
leukocytes increases due to proliferation and inhibition of granulocyte and monocyte precursors in the bone marrow which is stimulated by several products of
Leukocytosis
Life-threatening response to infection
death) of lymphocytes further worsens the immunosuppression. Neutrophils, monocytes, macrophages, dendritic cells, CD4+ T cells, and B cells all undergo apoptosis
Sepsis
Protein-coding gene in humans
including granulocytes, monocytes, macrophages and dendritic cells. Murine MICL is expressed as dimer on granulocytes, monocytes but also on B lymphocytes
CLEC12A
Mammalian protein found in humans
pathogen-associated molecular pattern (PAMP). It is highly expressed on monocytes and macrophages, and at lower levels on neutrophils and dendritic cells
CD14
Non-coding RNA in the species Homo sapiens
right lobe of thyroid gland muscle of leg bone marrow gastrocnemius muscle monocyte islet of Langerhans human kidney n/a More reference expression data BioGPS
MIR1271
Mammalian protein found in humans
of a receptor for monocyte chemoattractant protein-1 (CCL2), a chemokine which specifically mediates monocyte chemotaxis. Monocyte chemoattractant protein-1
CCR2
the recruitment of inflammation-resolving immune populations, including monocyte-derived macrophages and FoxP3⁺ regulatory T cells, to the CNS, and led
Michal_Schwartz
Topics referred to by the same term
Infectious mononucleosis, also known as glandular fever ("the kissing disease") Monocyte, a type of leukocyte (white blood cell) Monodactylidae, members of which
Mono
Medical condition
almost all blood cells (red blood cells, white blood cells, platelets, monocytes, lymphocytes, etc.). If only two parameters from the complete blood count
Pancytopenia
Type of allergic reaction
cell-mediated response. This response involves the interaction of T cells, monocytes, and macrophages. This reaction is caused when CD4+ Th1 cells recognize
Type_IV_hypersensitivity
Mammalian protein found in humans
procoagulant enzyme. Thrombomodulin is also expressed on human mesothelial cell, monocyte and a dendritic cell subset. In humans, thrombomodulin is encoded by the
Thrombomodulin
Protein-coding gene in the species Homo sapiens
encoded by this gene is an azurophil granule antimicrobial protein, with monocyte chemotactic and antibacterial activity. It is also an important multifunctional
Azurocidin_1
Medical condition
Generalized granuloma annulare is a skin condition of unknown cause, tending to affect women in the fifth and sixth decades, presenting as a diffuse but
Generalized granuloma annulare
Generalized_granuloma_annulare
Technology for detecting biomarkers
Epitope Detection in Monocytes (EDIM) is a technology that uses the innate immune system's mechanisms to detect biomarkers or antigens in immune cells
EDIM_technology
myelomonocytic leukemia. It bears a resemblance to both a myelocyte and monocyte. It is derived from CFU-GM. "Definition of myelomonocyte - NCI Dictionary
Myelomonocyte
Type of white blood cell
derive from circulating monocytes or are established before birth and then maintained during adult life independently of monocytes. By contrast, most of
Macrophage
Protein-coding gene in humans
Top expressed in muscle tissue cell blood somatic cell white blood cell monocyte renal cortex endometrium exocrine gland cervix Top expressed in zone of
DEFB105A
Colony forming unit that generates myeloid cells in the bone marrow
cells or myeloid stem cells. "GEMM" stands for granulocyte, erythrocyte, monocyte, megakaryocyte. The common myeloid progenitor (CMP) and the common lymphoid
CFU-GEMM
Mammalian protein found in Homo sapiens
properties of the alpha M beta 2 integrin in the adherence of neutrophils and monocytes to stimulated endothelium cells, and in the phagocytosis of complement
Integrin_alpha_X
Protein-coding gene in the species Homo sapiens
decision for a common myeloid progenitor (CMP) to differentiate into a monocyte precursor cell. Interferon Consensus Sequence-binding protein (ICSBP) is
IRF8
Protein-coding gene in the species Homo sapiens
Bgee Human Mouse (ortholog) Top expressed in testicle gonad granulocyte monocyte Achilles tendon sural nerve popliteal artery tibial arteries smooth muscle
DEC1
Type of blood cancer
myeloblastic leukemia M0 M1 M2 APL/M3 MP Chronic neutrophilic leukemia Monocyte AML AMoL/M5 Myeloid dendritic cell leukemia CML Philadelphia chromosome
Chronic_myelogenous_leukemia
Protein-coding gene in the species Homo sapiens
expression pattern Bgee Human Mouse (ortholog) Top expressed in granulocyte monocyte blood bone marrow bone marrow cell spleen periodontal fiber trabecular
LST1
responses Macrophage Monocyte Macrophage Macrophagocytus Mφ MΦ MP 20-21 Bacteria Viruses Fungi Cancer cells Cellular debris Histiocyte Monocyte Macrophage Tissue
List_of_immune_cells
Protein-coding gene in the species Homo sapiens
gene in humans (previously FYB). The protein is expressed in T cells, monocytes, mast cells, macrophages, NK cells, but not B cells. FYB is a multifunctional
FYB
pattern Bgee Human Mouse (ortholog) Top expressed in kidney gonad stomach monocyte placenta heart left ventricle intestine lung colon n/a More reference expression
MIR494
Subtype of white blood cell
blood showing red blood cells, several types of white blood cells including lymphocytes, a monocyte, a neutrophil and many small disc-shaped platelets
Lymphocyte
Mammalian protein found in humans
(Cluster of Differentiation 68) is a protein highly expressed by cells in the monocyte lineage (e.g., monocytic phagocytes, osteoclasts), by circulating macrophages
CD68
Protein-coding gene in the species Homo sapiens
blood monocytes and neutrophils, and upregulated by toll-like receptor (TLR) ligands; activation of TREM1 amplifies immune responses. Monocyte-, macrophage-
TREM1
Protein-coding gene in the species Homo sapiens
derangement of the tubular architecture by both myofibroblast buildup and monocyte infiltration Because endogenous BMP-7 is an inhibitor of the TGF-β signaling
Bone_morphogenetic_protein_7
Medical condition
crystalline cholesterol, cholesteryl esters, and phospholipids; cells such as monocyte derived macrophages, T-lymphocytes, and smooth muscle cells. The plaque
Cerebral_atherosclerosis
Macrophages located in the liver
macrophages, which must be continually renewed by circulating monocytes, these monocyte-derived Kupffer cells are capable of self-renewal once a population
Kupffer_cell
Contagious disease caused by SARS-CoV-2
colony-stimulating factor (GM‑CSF) Interferon gamma-induced protein 10 (IP‑10) Monocyte chemoattractant protein 1 (MCP1) Macrophage inflammatory protein 1‑alpha
COVID-19
Blood in circulatory system with round nucleus
These cells consist of lymphocytes (T cells, B cells, NK cells) and monocytes, whereas erythrocytes and platelets have no nuclei, and granulocytes (neutrophils
Peripheral blood mononuclear cell
Peripheral_blood_mononuclear_cell
Type of macrophage
Macrophages are known to originate from bone marrow-derived blood monocytes (monocyte-derived macrophages) or yolk sac progenitors (tissue-resident macrophages)
Tumor-associated_macrophage
Protein-coding gene in the species Homo sapiens
IL-34 increases growth or survival of monocytes. In cancer, IL-34 was shown to drive the migration of monocyte-derived tumor-associated macrophages in
Interleukin_34
Protein-coding gene in humans
Epithelium of choroid plexus epithelium of nasopharynx mononuclear cell monocyte cardia gallbladder Top expressed in otic placode saccule stroma of bone
MCL1
Protein-coding gene in the species Homo sapiens
pattern Bgee Human Mouse (ortholog) Top expressed in islet of Langerhans monocyte skin of leg tibial arteries smooth muscle tissue skin of abdomen ventricular
RRAGC
Protein-coding gene found in humans
cells from which these lymphocytes were derived. It also is found on monocytes and dendritic cells. Further, it is found within the male genital tract
CD52
Tumor derived from histiocytes
cells called histiocytes, which include macrophages, dendritic cells, and monocytes. Yamada R, Komohara Y (2024). "Histiocytic neoplasms: a brief review and
Histiocytic_neoplasm
Immune organ that filters blood
as other antibody-coated cells and pathogens. The red pulp also stores monocytes, which can be mobilized to travel to sites of tissue injury (such as the
Spleen
Protein-coding gene in the species Homo sapiens
anterior pituitary internal globus pallidus blood cerebellar hemisphere monocyte right frontal lobe Top expressed in lumbar subsegment of spinal cord bone
APOL2
Topics referred to by the same term
MCP1 may refer to: Monocyte chemoattractant protein 1 (MCP1 or MCP-1), cytokine also known as CCL2 Mast cell protease 1, enzyme also known as chymase Tennelec
MCP1
Type of tissue in the spleen
large reservoir for monocytes. These monocytes are found in clusters in the Billroth's cords (red pulp cords). The population of monocytes in this reservoir
Red_pulp
Species of bacteria
response as a first-line immune system defence. Phagocytic leukocytes and monocytes infiltrate the site of infection, and antibodies are produced. H. pylori
Helicobacter_pylori
Pseudogene in the species Homo sapiens
testicle bone marrow cell lymph node somatic cell white blood cell blood monocyte tibial nerve tibial arteries skin of leg n/a More reference expression
H2BC12L
Removal of pyrogens from solutions
free CD14 in the serum or bound to the cell surface of macrophages or monocytes). This monomerises the aggregated LPS, as the LPS receptor Toll-like Receptor
Depyrogenation
Early onset muscle loss due to ageing or immobility
protein, tumor necrosis factor, interleukin-8, interleukin-6, granulocyte-monocyte colony-stimulating factor, interferons, and serine protease A1. Changes
Sarcopenia
Mammalian protein found in Homo sapiens
surface of many leukocytes involved in the innate immune system, including monocytes, granulocytes, macrophages, and natural killer cells and subsets of T
Integrin_alpha_M
Protein-coding gene in the species Homo sapiens
(October 1996). "Differential screening identifies genetic markers of monocyte to macrophage maturation". Journal of Leukocyte Biology. 60 (4): 540–545
WARS1
Protein-coding gene in the species Homo sapiens
pattern Bgee Human Mouse (ortholog) Top expressed in granulocyte blood monocyte bone marrow stromal cell of endometrium spleen bone marrow cell trabecular
FOLR3
Mammalian protein found in humans
Chemokine (C-C motif) ligand 8 (CCL8), also known as monocyte chemoattractant protein 2 (MCP2), is a protein that in humans is encoded by the CCL8 gene
CCL8
Protein-coding gene in the species Homo sapiens
encoded by the TREM2 gene. TREM2 is expressed on macrophages, immature monocyte-derived dendritic cells, osteoclasts, and microglia, which are immune cells
TREM2
Human gene
was identified by reactivity with a monoclonal antibody, is present on monocytes, neutrophils, and some T and B lymphocytes. CD300A is recognized by the
CD300A
Protein found in humans
increased expression of CD11b and an enhanced adhesion of circulating monocytes to fibronectin". Diabetes. 53 (8): 1979–1986. doi:10.2337/diabetes.53
ABCC11
They are most often observed in neutrophils, but can also appear in monocytes, lymphocytes, eosinophils. They may appear in patients on immunosuppression
Howell-Jolly body-like inclusions
Howell-Jolly_body-like_inclusions
Protein found in humans
expression pattern Bgee Human Mouse (ortholog) Top expressed in blood monocyte skin of leg bone marrow skin of abdomen islet of Langerhans olfactory zone
Adiponectin_receptor_1
Branch of pathology that studies and diagnoses diseases on the cellular level
plate may cause smearing artifacts, such as the nuclear smearing of this monocyte, shown as tail-like extension of nuclear material. Cervical squamous cells
Cytopathology
Inflammatory disease featuring pain and stiffness
polymyalgia rheumatica includes the activation of dendritic cells and monocytes/macrophages, leading to inflammation in the synovium and bursae of the
Polymyalgia_rheumatica
Disease treatment
tuberculosis. The addition of vitamin D appears to enhance the ability of monocytes and macrophages to kill M. tuberculosis in vitro as well as ameliorating
Management_of_tuberculosis
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