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Protein found in humans
molecules from inside a cell. It is a protein that in humans is encoded by gene ABCC11. The gene is responsible for determination of human cerumen type (wet or
ABCC11
Odor produced by a living animal
be to prevent inbreeding. The ABCC11 gene determines axillary body odor and earwax type. The loss of a functional ABCC11 gene is caused by a 538G>A single-nucleotide
Body_odor
Waxy substance secreted by the ear
T, Ninokata A, Ishikawa T, Kaname T, et al. (March 2006). "A SNP in the ABCC11 gene is the determinant of human earwax type". Nature Genetics. 38 (3):
Earwax
Biochemistry
secretions and normal skin microflora. In addition, androstane steroids and the ABCC11 transporter are essential for most axillary odor. Body odor is a complex
Biochemistry_of_body_odor
People of East Asia
IUP-affiliated Bacho Kiro cave remains. The majority of East Asians have the ABCC11 gene (80-95%), which greatly reduces body odor and codes for dry-type earwax
Ethnic_groups_in_East_Asia
Chemical compound
Apocrine sweat glands produce an S-glutathione conjugate secreted via ABCC11 transporters into vesicles. The conjugate is converted into a S-Cys-Gly-3M3SH
3-Methyl-3-sulfanylhexan-1-ol
Protein-coding gene in the species Homo sapiens
new genes from the human ATP-binding cassette transporter superfamily, ABCC11 and ABCC12, tandemly duplicated on chromosome 16q12". Gene. 273 (1): 89–96
ABCC12
Health problem from genome abnormalities
T, Ninokata A, Ishikawa T, Kaname T, et al. (March 2006). "A SNP in the ABCC11 gene is the determinant of human earwax type". Nature Genetics. 38 (3):
Genetic_disorder
Japanese physician and medical geneticist
research group identified a single nucleotide polymorphism (SNP) in the ABCC11 gene is the determinant of human earwax type. Niikawa obtained his medical
Norio_Niikawa
Cave and archaeological site in Russia
EDAR allele commonly found in modern East Asian populations, the derived ABCC11 allele associated with dry earwax and reduced body odor commonly found in
Chertovy_Vorota_Cave
Genetic diversity in human populations
are relatively small, these differences in certain genes such as duffy, ABCC11, SLC24A5, called ancestry-informative markers (AIMs) nevertheless can be
Human_genetic_variation
Main transmembrane structural unit of ATP-binding cassette transporter proteins
ABCB10; ABCB11; ABCB4; ABCB5; ABCB6; ABCB7; ABCB8; ABCB9; ABCC1; ABCC10; ABCC11; ABCC12; ABCC13; ABCC2; ABCC3; ABCC4; ABCC5; ABCC6; ABCC8; ABCC9; CFTR;
Transmembrane domain of ABC transporters
Transmembrane_domain_of_ABC_transporters
Water-soluble domain of transmembrane ABC transporters
ABCB10; ABCB11; ABCB4; ABCB5; ABCB6; ABCB7; ABCB8; ABCB9; ABCC1; ABCC10; ABCC11; ABCC12; ABCC2; ABCC3; ABCC4; ABCC5; ABCC6; ABCC8; ABCC9; ABCD1; ABCD2;
ATP-binding domain of ABC transporters
ATP-binding_domain_of_ABC_transporters
ABCC8 HGNC:59; Q09428 59 ABCC9 HGNC:60; O60706 60 ABCC10 HGNC:52; Q5T3U5 61 ABCC11 HGNC:14639; Q96J66 62 ABCC12 HGNC:14640; Q96J65 63 ABCD1 HGNC:61; P33897
List of human protein-coding genes 1
List_of_human_protein-coding_genes_1
ABCC11
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