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Medication used to treat diabetes
Metformin, sold under the brand name Glucophage, among others, is the main first-line medication for the treatment of type 2 diabetes, particularly in
Metformin
Pharmaceutical drug
Sitagliptin/metformin, sold under the brand name Janumet among others, is a fixed-dose combination anti-diabetic medication used to treat type 2 diabetes
Sitagliptin/metformin
Diabetes medication
type 2 diabetes as an adjunct to diet and exercise As monotherapy when metformin is considered inappropriate due to intolerance In addition to other medicinal
Dapagliflozin
Two drugs combined to treat diabetes
Dapagliflozin/metformin, sold under the brand name Xigduo Xr among others, is a fixed-dose combination anti-diabetic medication used as an adjunct to
Dapagliflozin/metformin
Pharmaceutical drug
Empagliflozin/metformin, sold under the brand name Synjardy among others, is a fixed-dose combination anti-diabetic medication used to treat type 2 diabetes
Empagliflozin/metformin
Combination drug
Pioglitazone/metformin, sold under the brand name Actoplus Met among others, is a fixed-dose combination anti-diabetic medication used to improve glycemic
Pioglitazone/metformin
Combination drug
Empagliflozin/linagliptin/metformin, sold under the brand name Trijardy XR, is a fixed-dose combination medication used for the treatment of type 2 diabetes
Empagliflozin/linagliptin/metformin
Empagliflozin/linagliptin/metformin
Hormonal disorder affecting the female repoductive system
help regulate menstrual cycles and reduce acne and excess hair growth. Metformin, a common anti-diabetes drug, increases insulin sensitivity. For fertility
Polyendocrine metabolic ovarian syndrome
Polyendocrine_metabolic_ovarian_syndrome
Pharmaceutical drug
Vildagliptin/metformin, sold under the brand name Eucreas among others, is a fixed-dose combination anti-diabetic medication for the treatment of type
Vildagliptin/metformin
Diabetes medication
preferred than metformin or a sulfonylurea. It is taken by mouth. It is also available in the fixed-dose combination medication sitagliptin/metformin (Janumet
Sitagliptin
Form of diabetes mellitus
fat). Treatment may involve exercise, dietary changes, and medication. Metformin is often recommended. Many people may eventually also require insulin
Type_2_diabetes
Combination drug
Glibenclamide/metformin, also known as glyburide/metformin and sold under the brand name Glucovance, is a fixed-dose combination anti-diabetic medication
Glibenclamide/metformin
Anti-diabetic and anti-obesity medication
type 2 diabetes as an adjunct to diet and exercise as monotherapy when metformin is considered inappropriate due to intolerance or contraindications, in
Semaglutide
Drugs that lower blood glucose levels to treat diabetes
approved in 2019, consisting of metformin, saxagliptin, and dapagliflozin. Another triple combination approval for metformin, linagliptin, and empagliflozin
Diabetes_medication
Class of medication
line pharmacological therapy for type 2 diabetes (usually together with metformin), specifically in patients with chronic kidney disease, cardiovascular
SGLT2_inhibitor
Anti-diabetic medication
a second-line therapy for diabetes following first-line therapy with metformin. Its effects on long-term health outcomes like heart disease and life
Liraglutide
Anti-diabetic drug
commonly used in combination with metformin in people whose diabetes cannot adequately be controlled with metformin alone. In April 2016, the U.S. Food
Alogliptin
Anti-obesity medication
Empagliflozin/metformin Gemigliptin/rosuvastatin Glibenclamide (glyburide)/metformin Glimepiride/rosiglitazone Linagliptin/metformin Metformin/acarbose Metformin/ertugliflozin
Orforglipron
Combination drug
Dapagliflozin/saxagliptin/metformin, sold under the brand name Qternmet XR among others, is a fixed-dose combination anti-diabetic medication used as
Dapagliflozin/saxagliptin/metformin
Dapagliflozin/saxagliptin/metformin
Species of flowering plant in the pea family
blood glucose-lowering activity and the foundation for the discovery of metformin, a treatment for managing symptoms of diabetes mellitus. In ancient herbalism
Galega_officinalis
Diabetes medication
nausea and vomiting may occur and seem more pronounced in combination with metformin. Rare but serious adverse events, such as euglycemic diabetic ketoacidosis
Empagliflozin
Chemical compound
monotherapy and as a fixed dose combination with either sitagliptin or with metformin. In the European Union, it was approved in March 2018, for use as a monotherapy
Ertugliflozin
Fixed-dose combination anti-diabetic medication
Canagliflozin/metformin, sold under the brand name Vokanamet among others, is a fixed-dose combination anti-diabetic medication used for the treatment
Canagliflozin/metformin
Chemical compound
not controlled by diet and exercise alone. It is not as good as either metformin or insulin in those who have gestational diabetes. Frequently reported
Glibenclamide
Class of organic compounds used in medicine and agriculture
limited evidence if the combined use of Metformin with Sulphonylurea compared to the combination of Metformin plus another glucose-lowering intervention
Sulfonylurea
Class of drugs used to treat diabetes
Empagliflozin/metformin Gemigliptin/rosuvastatin Glibenclamide (glyburide)/metformin Glimepiride/rosiglitazone Linagliptin/metformin Metformin/acarbose Metformin/ertugliflozin
GLP1_poly-agonist_peptides
Medication
potentially other antidiabetic medication. It is a treatment option after metformin and sulfonylureas. It is given by injection under the skin. Common side
Exenatide
Chemical compound
Agency has also approved a combination of vildagliptin and metformin, vildagliptin/metformin (Eucreas by Novartis) as an oral treatment for type-2 diabetes
Vildagliptin
Gastrointestinal peptide hormone involved in glucose homeostasis
Empagliflozin/metformin Gemigliptin/rosuvastatin Glibenclamide (glyburide)/metformin Glimepiride/rosiglitazone Linagliptin/metformin Metformin/acarbose Metformin/ertugliflozin
Glucagon-like_peptide-1
Pharmaceutical compound
Empagliflozin/metformin Gemigliptin/rosuvastatin Glibenclamide (glyburide)/metformin Glimepiride/rosiglitazone Linagliptin/metformin Metformin/acarbose Metformin/ertugliflozin
Brenipatide
Chemical compound
used for diabetes mellitus or prediabetes treatment. Examples include: Metformin - widely used in treatment of diabetes mellitus type 2 Phenformin - withdrawn
Biguanide
Long-acting insulin
Empagliflozin/metformin Gemigliptin/rosuvastatin Glibenclamide (glyburide)/metformin Glimepiride/rosiglitazone Linagliptin/metformin Metformin/acarbose Metformin/ertugliflozin
Insulin_glargine
Anti-diabetic and anti-obesity medication
Empagliflozin/metformin Gemigliptin/rosuvastatin Glibenclamide (glyburide)/metformin Glimepiride/rosiglitazone Linagliptin/metformin Metformin/acarbose Metformin/ertugliflozin
Tirzepatide
Medication
diabetes. It is regarded as a second-line option compared to metformin, due to metformin's well-established safety and efficacy. Use of glimepiride is
Glimepiride
Chemical compound
anti-diabetic medication used to treat type 2 diabetes. It may be used with metformin, a sulfonylurea, or insulin. Use is recommended together with exercise
Pioglitazone
Pharmaceutical drug classification
Metformin and alogliptin A10BD14 Metformin and repaglinide A10BD15 Metformin and dapagliflozin A10BD16 Metformin and canagliflozin A10BD17 Metformin and
ATC_code_A10
Diabetes medication
in combination with other medicines for type 2 diabetes, in particular metformin, sulfonylureas, thiazolidinediones, and insulin taken concomitantly with
Dulaglutide
GLP1 poly-agonist drug
Empagliflozin/metformin Gemigliptin/rosuvastatin Glibenclamide (glyburide)/metformin Glimepiride/rosiglitazone Linagliptin/metformin Metformin/acarbose Metformin/ertugliflozin
Mazdutide
Enzyme blocker and diabetes treatment drug
Cochrane systematic review found insufficient evidence to suggest that metformin monotherapy reduced all-cause mortality, serious adverse events, cardiovascular
Dipeptidyl peptidase-4 inhibitor
Dipeptidyl_peptidase-4_inhibitor
Series of interconnected biochemical reactions
glycerol from lipolysis. The drug metformin can cause lactic acidosis in patients with kidney failure because metformin inhibits the hepatic gluconeogenesis
Cori_cycle
Rapid-acting man-made insulin
Empagliflozin/metformin Gemigliptin/rosuvastatin Glibenclamide (glyburide)/metformin Glimepiride/rosiglitazone Linagliptin/metformin Metformin/acarbose Metformin/ertugliflozin
Insulin_aspart
Class of chemical compounds
infarction, non-fatal stroke or end-stage renal disease when comparing metformin monotherapy to Thiazolidinedione for treatment of type 2 diabetes. Thiazolidinediones
Thiazolidinedione
Empagliflozin/metformin Gemigliptin/rosuvastatin Glibenclamide (glyburide)/metformin Glimepiride/rosiglitazone Linagliptin/metformin Metformin/acarbose Metformin/ertugliflozin
List of commercially available insulins
List_of_commercially_available_insulins
Chemical compound
Empagliflozin/metformin Gemigliptin/rosuvastatin Glibenclamide (glyburide)/metformin Glimepiride/rosiglitazone Linagliptin/metformin Metformin/acarbose Metformin/ertugliflozin
Retatrutide
Chemical compound
GlaxoSmithKline (GSK) as a stand-alone drug or for use in combination with metformin or with glimepiride. First released in 1999, annual sales peaked at approximately
Rosiglitazone
Chemical compound
Empagliflozin/metformin Gemigliptin/rosuvastatin Glibenclamide (glyburide)/metformin Glimepiride/rosiglitazone Linagliptin/metformin Metformin/acarbose Metformin/ertugliflozin
Lotiglipron
Chemical compound
Empagliflozin/metformin Gemigliptin/rosuvastatin Glibenclamide (glyburide)/metformin Glimepiride/rosiglitazone Linagliptin/metformin Metformin/acarbose Metformin/ertugliflozin
Sotagliflozin
Chemical compound
Empagliflozin/metformin Gemigliptin/rosuvastatin Glibenclamide (glyburide)/metformin Glimepiride/rosiglitazone Linagliptin/metformin Metformin/acarbose Metformin/ertugliflozin
Danuglipron
Medication
Empagliflozin/metformin Gemigliptin/rosuvastatin Glibenclamide (glyburide)/metformin Glimepiride/rosiglitazone Linagliptin/metformin Metformin/acarbose Metformin/ertugliflozin
Dasiglucagon
Chemical compound
by itself, in combination with metformin, in combination with metformin and a sulfonylurea, in combination with metformin and pioglitazone, or in combination
Canagliflozin
Use of insulin protein and analogs as medical treatment
Retrieved 4 January 2023. Foretz M, Guigas B, Viollet B (August 2023). "Metformin: update on mechanisms of action and repurposing potential". Nature Reviews
Insulin_(medication)
Combination drug
Empagliflozin/metformin Gemigliptin/rosuvastatin Glibenclamide (glyburide)/metformin Glimepiride/rosiglitazone Linagliptin/metformin Metformin/acarbose Metformin/ertugliflozin
Insulin_icodec/semaglutide
Ultralong-acting basal insulin analogue
Empagliflozin/metformin Gemigliptin/rosuvastatin Glibenclamide (glyburide)/metformin Glimepiride/rosiglitazone Linagliptin/metformin Metformin/acarbose Metformin/ertugliflozin
Insulin_icodec
Israeli geneticist
genetics influence lifespan. He has also proposed metformin as a tool to target aging and has run the Metformin in Longevity Study (completed May 2018) He is
Nir_Barzilai
Chemical compound
"Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin". The New England Journal of Medicine. 346 (6): 393–403. doi:10.1056/NEJMoa012512
Troglitazone
Vitamin used in animal cell metabolism
proton-pump inhibitors, H2 blockers, or other antacids, and interaction with metformin. Elderly people – due to impaired intestinal absorption – and children
Vitamin_B12
Rapid-acting insuline analog
Empagliflozin/metformin Gemigliptin/rosuvastatin Glibenclamide (glyburide)/metformin Glimepiride/rosiglitazone Linagliptin/metformin Metformin/acarbose Metformin/ertugliflozin
Insulin_lispro
Modified forms of synthetic insulin
of Insulin Tregopil and Its Permeation Enhancer on Pharmacokinetics of Metformin in Healthy Volunteers: Randomized, Open-Label, Placebo-Controlled, Crossover
Insulin_analogue
Diabetes drug
Empagliflozin/metformin Gemigliptin/rosuvastatin Glibenclamide (glyburide)/metformin Glimepiride/rosiglitazone Linagliptin/metformin Metformin/acarbose Metformin/ertugliflozin
Lixisenatide
Diabetes medication
Empagliflozin/metformin Gemigliptin/rosuvastatin Glibenclamide (glyburide)/metformin Glimepiride/rosiglitazone Linagliptin/metformin Metformin/acarbose Metformin/ertugliflozin
Pramlintide
Pharmaceutical compound
Empagliflozin/metformin Gemigliptin/rosuvastatin Glibenclamide (glyburide)/metformin Glimepiride/rosiglitazone Linagliptin/metformin Metformin/acarbose Metformin/ertugliflozin
Conveglipron
Drug used for the treatment of symptoms of metabolic syndrome
Empagliflozin/metformin Gemigliptin/rosuvastatin Glibenclamide (glyburide)/metformin Glimepiride/rosiglitazone Linagliptin/metformin Metformin/acarbose Metformin/ertugliflozin
PPAR_agonist
Chemical compound
oral antidiabetic drug of the biguanide class, chemically related to metformin and phenformin. Buformin was marketed by German pharmaceutical company
Buformin
Antidiabetic medication
controlled trial comparing bexagliflozin to glimepiride as an adjunct to metformin for the treatment of type 2 diabetes in adults". Diabetes, Obesity and
Bexagliflozin
Chemical compound
recalled Chinese "herbal products" containing phenformin. The related drug metformin is considerably safer than phenformin, with three cases of lactic acidosis
Phenformin
Chemical compound
cannot be controlled by proper dietary management and exercise and when metformin has already been tried. National Kidney Foundation (2012 Update) claims
Gliclazide
Chemical compound
conclusive evidence that acarbose, when compared to diet and exercise, metformin, placebo, or no intervention, improved all-cause mortality, reduced or
Acarbose
Ultralong-acting basal insulin analogue
insulin glargine (n=251), in addition to either mealtime insulin aspart, metformin, and/or pioglitazone. Participants in this trial had an average HbA1c
Insulin_degludec
Beta-lactam antibiotic
Cefalexin also interacts with metformin, an antidiabetic drug, and this can lead to higher concentrations of metformin in the body. Histamine H2 receptor
Cefalexin
Chemical compound
its potential use in cancer treatment. Chemically, it is derivative of metformin and a potent oxidative phosphorylation inhibitor and AMP-activated protein
HL156A
Alpha-glucosidase inhibitor
Empagliflozin/metformin Gemigliptin/rosuvastatin Glibenclamide (glyburide)/metformin Glimepiride/rosiglitazone Linagliptin/metformin Metformin/acarbose Metformin/ertugliflozin
Voglibose
Powdered insulin delivered with an inhaler
Empagliflozin/metformin Gemigliptin/rosuvastatin Glibenclamide (glyburide)/metformin Glimepiride/rosiglitazone Linagliptin/metformin Metformin/acarbose Metformin/ertugliflozin
Inhalable_insulin
Chemical compound
Empagliflozin/metformin Gemigliptin/rosuvastatin Glibenclamide (glyburide)/metformin Glimepiride/rosiglitazone Linagliptin/metformin Metformin/acarbose Metformin/ertugliflozin
Saroglitazar
Chemical compound
diabetes. Combination therapy with saxagliptin and metformin was more effective than saxagliptin or metformin monotherapy. When the relative benefits of increasing
Saxagliptin
Medical condition
Toxins (Ethylene glycol, methanol, as well as drugs, such as aspirin, Metformin) The mnemonic for toxins is ACE GIFTs: Aspirin, Cyanide, Ethanolic ketosis
High anion gap metabolic acidosis
High_anion_gap_metabolic_acidosis
Intermediate acting insulin formulation
Empagliflozin/metformin Gemigliptin/rosuvastatin Glibenclamide (glyburide)/metformin Glimepiride/rosiglitazone Linagliptin/metformin Metformin/acarbose Metformin/ertugliflozin
NPH_insulin
Chemical compound
combination therapy of repaglinide together with the generic anti-diabetic drug metformin. This new patent was due to expire June 2018. In January 2011, a federal
Repaglinide
Chemical compound
gemigliptin/metformin and metformin groups. The mean daily doses of metformin at week 24 were 1,699 and 1,868 mg for the gemigliptin/metformin group and
Gemigliptin
Chemical compound
Empagliflozin/metformin Gemigliptin/rosuvastatin Glibenclamide (glyburide)/metformin Glimepiride/rosiglitazone Linagliptin/metformin Metformin/acarbose Metformin/ertugliflozin
Glipizide
Management of diabetes
most common drugs used in T2D, metformin is the drug of choice to help patients lower their blood sugar levels. Metformin is an example of a class of medicine
Diabetes_management
Chemical compound
production of glucagon by the pancreas. It is generally less preferred than metformin and sulfonylureas as an initial treatment. It is taken by mouth. Common
Linagliptin
Chemical compound
samples of the diabetes drug metformin for NDMA. The FDA announcement followed a recall of three versions of metformin in Singapore, and the European
N-Nitrosodimethylamine
Chemical compound
interaction between DWP16001, an sodium–glucose cotransporter 2 inhibitor and metformin in healthy subjects". British Journal of Clinical Pharmacology. 89 (4):
Enavogliflozin
Chemical substance
infarction, non-fatal stroke or end-stage renal disease when comparing metformin monotherapy to meglitinide for the treatment of type 2 diabetes. They
Meglitinide
Historical formulation of insulin as medication
Empagliflozin/metformin Gemigliptin/rosuvastatin Glibenclamide (glyburide)/metformin Glimepiride/rosiglitazone Linagliptin/metformin Metformin/acarbose Metformin/ertugliflozin
Lente_insulin
Medication
Empagliflozin/metformin Gemigliptin/rosuvastatin Glibenclamide (glyburide)/metformin Glimepiride/rosiglitazone Linagliptin/metformin Metformin/acarbose Metformin/ertugliflozin
Dapagliflozin/sitagliptin
Short-acting insulin formulation
Empagliflozin/metformin Gemigliptin/rosuvastatin Glibenclamide (glyburide)/metformin Glimepiride/rosiglitazone Linagliptin/metformin Metformin/acarbose Metformin/ertugliflozin
Regular_insulin
Medication
Empagliflozin/metformin Gemigliptin/rosuvastatin Glibenclamide (glyburide)/metformin Glimepiride/rosiglitazone Linagliptin/metformin Metformin/acarbose Metformin/ertugliflozin
Velagliflozin
Combination drug
Empagliflozin/metformin Gemigliptin/rosuvastatin Glibenclamide (glyburide)/metformin Glimepiride/rosiglitazone Linagliptin/metformin Metformin/acarbose Metformin/ertugliflozin
Sitagliptin/simvastatin
Species of fish native to Southeast Asia
Betta splendens' behavior is metformin, which is a drug doctors prescribe to treat people with type II diabetes. Metformin can enter freshwater and wastewater
Siamese_fighting_fish
Group of endocrine diseases characterized by high blood sugar levels
therapy (insulin injections), while anti-diabetic medications (such as metformin and semaglutide or tirzepatide) and lifestyle modifications can be used
Diabetes
Norwegian pharmaceutical company
facilities in Kragerø. Weifa is one of the world’s largest producers of Metformin hydrochloride and a leading producer of alkaloid opiates. Production facilities
Weifa
Chemical compound
Empagliflozin/metformin Gemigliptin/rosuvastatin Glibenclamide (glyburide)/metformin Glimepiride/rosiglitazone Linagliptin/metformin Metformin/acarbose Metformin/ertugliflozin
Miglitol
Chemical compound
Empagliflozin/metformin Gemigliptin/rosuvastatin Glibenclamide (glyburide)/metformin Glimepiride/rosiglitazone Linagliptin/metformin Metformin/acarbose Metformin/ertugliflozin
Glisoxepide
Chemical compound
Empagliflozin/metformin Gemigliptin/rosuvastatin Glibenclamide (glyburide)/metformin Glimepiride/rosiglitazone Linagliptin/metformin Metformin/acarbose Metformin/ertugliflozin
Retagliptin
Chemical compound
remogliflozin etabonate, either 500 mg or 750 mg BID (twice a day), with metformin 2000 mg BID was safe and effective in patients with type 2 diabetes mellitus
Remogliflozin_etabonate
Biosynthesis of glucose molecules
increased levels of hyperglycemia in the body. The anti-diabetic drug metformin reduces blood glucose primarily through inhibition of gluconeogenesis
Gluconeogenesis
Chemical compound
treatment of metformin is not achieving the expected glycemic goals; though it has been approved for use as a first line treatment when metformin cannot be
Trelagliptin
Chemical compound
alternatives. Research on galegine eventually led to the development of metformin which is used today for treatment of type 2 diabetes. Nitensidine D Oldham
Galegine
Long-acting man-made insulin
Empagliflozin/metformin Gemigliptin/rosuvastatin Glibenclamide (glyburide)/metformin Glimepiride/rosiglitazone Linagliptin/metformin Metformin/acarbose Metformin/ertugliflozin
Insulin_detemir
METFORMIN
METFORMIN
METFORMIN
METFORMIN
METFORMIN
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METFORMIN