AI & ChatGPT searches , social queries for LOGP
Search references for LOGP. Phrases containing LOGP
See searches and references containing LOGP!
Search references for LOGP. Phrases containing LOGP
See searches and references containing LOGP!LOGP
Topics referred to by the same term
LogP may refer to: the logarithm of the partition coefficient, in the physical sciences LogP machine, a model for parallel computation p-adic logarithm
LogP
Parameter used in drug design
instead of the measured LogP or LogD. LiPE is used to compare compounds of different potencies (pIC50s) and lipophilicities (LogP). High potency (high value
Lipophilic_efficiency
The LogP machine is a model for parallel computation. It aims at being more practical than the PRAM model while still allowing for easy analysis of computation
LogP_machine
Chemical information database
Example (Lipinski's Rule of Five): 0:500[mw] 0:5[hbdc] 0:10[hbac] -5:5[logp] Chemical database CAS Common Chemistry - run by the American Chemical Society
PubChem
Benzodiazepine sedative
with LogP (Octanol-Water Partition Coefficient) value of 2,82 and hydrophilic with a TPSA (Topological Polar Surface Area) value of 32.7 Ų. The LogP value
Diazepam
Short chains of 2–50 amino acids
molecular properties used for mapping include molecular weight, lipophilicity (logP and logD), topological polar surface area (TPSA), and hydrogen-bond dynamics
Peptide
Medication used to treat diabetes
lipid solubility of the nonionized species is slight as shown by its low logP value (log(10) of the distribution coefficient of the nonionized form between
Metformin
Chemical compound
The lipophilicity of fluorenol (LogP 2.4) is higher than that of drugs like modafinil (LogP 1.7) and amphetamine (LogP 1.8), suggesting that it may penetrate
Fluorenol
Rule of thumb to predict if a chemical compound is likely to be an orally active drug
PMID 14554012. Free online calculations of Hydrogen bond donor/acceptor, mass and logP using ChemAxon's Marvin and Calculator Plugins – requires Java Calculation
Lipinski's_rule_of_five
Concept in drug design
alcohol), so the logarithm of the octanol-water partition coefficient, known as LogP, is used to predict the solubility of a potential oral drug. This coefficient
Druglikeness
Antiretroviral medication
Property Value Unit Source Molecular Weight 720.9 g/mol logP 3.9 - Water Solubility 0.00126 mg/mL Basic pKa 2.84 - Acidic pKa 13.68 Refractivity 194.59
Ritonavir
Medication, stimulant and decongestant
and Leo54 found that blood-brain barrier penetration is optimal when the LogP values are in the range of 1.5-2.7, with a mean value of 2.1. An analysis
Ephedrine
Ratio of concentrations in a mixture at equilibrium
org. Overview of the many logP and other physical property calculators available commercially and on-line. XLOGP3, a simple LogP estimator used by PubChem
Partition_coefficient
Abstraction of parallel computer architecture
Flink Functional Message passing Task Concurrent Haskell, Concurrent ML LogP machine Synchronous message passing Not specified None Parallel random access
Parallel_programming_model
Chemical compound
partition coefficient in non-polar medium, as characterized by experimental logP 5.284 Myristamine oxide – An analogous compound with a C14 tail Birnie, C
Lauryldimethylamine_oxide
Measure of lipophilicity and hydrophilicity
PMC 1568760. PMID 3905374. Kellogg GE, Abraham DJ (July 2000). "Hydrophobicity: is LogP(o/w) more than the sum of its parts?". European Journal of Medicinal Chemistry
Octanol-water partition coefficient
Octanol-water_partition_coefficient
Online chemistry tool
elemental analysis, names and identifiers (IUPAC name, SMILES, InChI), pKa, logP/logD, and solubility. Chemical Search Structure-based and text-based search
Chemicalize
Predictive chemical model
methods (known as "CLogP" and other variations). It has been shown that the logP of compound can be determined by the sum of its fragments; fragment-based
Quantitative structure–activity relationship
Quantitative_structure–activity_relationship
Sympathomimetic agent
and Leo54 found that blood-brain barrier penetration is optimal when the LogP values are in the range of 1.5-2.7, with the mean value of 2.1. An analysis
Phenylpropanolamine
Synthetic decongestant
and Leo54 found that blood-brain barrier penetration is optimal when the LogP values are in the range of 1.5-2.7, with the mean value of 2.1. An analysis
Pseudoephedrine
Software for drawing chemical structures
Apply styling according to publisher policies Property predictions (pKa, logP, logS, etc) ChemDraw Professional Desktop application Name-to-structure and
ChemDraw
Hypnotic medication
Zopiclone's solubility in water, at room temperature (25 °C) are 0.151 mg/mL. The logP value of zopiclone is 0.8. Zopiclone may be measured in blood, plasma, or
Zopiclone
Hungarian cheminformatics software company
been referenced in cheminformatics studies for predicting pKa values and logP values. Cheminformatics Computational chemistry Molecular modeling Drug discovery
Chemaxon
Beta blocker medication
properties of metoprolol Property Value Unit Source Molecular Weight 267.36 g/mol logP 1.6 - 2.15 - . Melting point 120 °C Boiling point 398 °C Water Solubility
Metoprolol
Antibiotic medication
uncharged state. It is moderately water-soluble (approximately 3 mg/mL), with a logP of 0.55. The oxazolidinone pharmacophore—the chemical "template" essential
Linezolid
Airport in Austria
Pinkafeld Airport (German: Flugplatz Pinkafeld, ICAO: LOGP) is a private use airport located 2 kilometres (1 mi) north-northwest of Pinkafeld, Burgenland
Pinkafeld_Airport
Two dwarf galaxies orbiting the Milky Way
home.insightbb.com. Archived from the original on 2003-04-29. "The (MK, logP) and (Mbol, log P) relations". aa.springer.de. Archived from the original
Magellanic_Clouds
Class of chemical compounds
of the steroid, as measured by the octanol/water partition coefficient (logP), the slower its release from the oily depot at the injection site and the
Steroid_ester
Mathematical structure
Indeed, fixing a reference lattice L, the label of M is given by label(M) = logp |M / pk L| modulo n for k sufficiently large. The vertices of any (n – 1)-simplex
Building_(mathematics)
Biochemical research competition
SAMPL6 Part 1 (host-guest) SAMPL6 Part 2 (logP) Issue 1 SAMPL6 Part 2 (logP) Issue 2 SAMPL7 host-guest SAMPL7 logP (Issue 1, Issue 2, additional article)]
SAMPL_Challenge
Chemical compound
phenylquinone writhing and tail-flick assays. One reason for the high potency is the LogP of 4.57, allowing it to accumulate in fatty tissue such as the brain. AH-7921
U-77891
Software development company based in Toronto, Ontario, Canada
such as NMR spectra and various physico-chemical properties, such as pKa, logP, logD, boiling point, vapor pressure. Early on the development focused on
Advanced Chemistry Development
Advanced_Chemistry_Development
Software application for cheminformatics
descriptors, charge descriptors, and more. Molecular properties: including LogP (octanol-water partition coefficient), molar refractivity, polar surface
AlvaDesc
Experimental dopamine prodrug
and Leo54 found that blood-brain barrier penetration is optimal when the LogP values are in the range of 1.5-2.7, with the mean value of 2.1. An analysis
O,O′-Diacetyldopamine
Synthetic dopamine prodrug
and Leo54 found that blood-brain barrier penetration is optimal when the LogP values are in the range of 1.5-2.7, with the mean value of 2.1. An analysis
O,O′-Dipivaloyldopamine
Class of compounds based upon the β-hydroxyamphetamine structure
and Leo54 found that blood-brain barrier penetration is optimal when the LogP values are in the range of 1.5-2.7, with the mean value of 2.1. An analysis
Substituted β-hydroxyamphetamine
Substituted_β-hydroxyamphetamine
Chemical compound
has also been used. The experimental octanol/water partition coefficient (logP) of estradiol enanthate is 6.7. Estradiol enanthate was first described,
Estradiol_enanthate
Chemical compound
sodium estrone sulfate and estropipate (piperazine estrone sulfate). The logP of E1S is 1.4. Kuhl H (August 2005). "Pharmacology of estrogens and progestogens:
Estrone_sulfate_(medication)
American computer scientist
Parallel Complexity within the LogP Model was based on her work with Karp and others introducing and analyzing the LogP machine, an abstract model of parallel
Eunice_Santos
Binding relation that may employ a morphologically different set of anaphoric forms
LogP projection of the logophoric operator, where its complement 'α' contains the exempt anaphor which the silent logophoric pronoun binds. The LogP projection
Logophoricity
Chemical compound
willardiine PROPERTY VALUE SOURCE Water solubility 13.2 mg/mL ALOGPS logP -0.7 ALOGPS logP -1.3 ChemAxon logS -1.2 ALOGPS pKa (Strongest Acidic) 9.76 ChemAxon
Willardiine
properties of solvents and solutions (solubility, partition coefficient (LogP), vapor–liquid equilibrium (VLE), LLE) with COSMO-RS Semi-empirical modules
Amsterdam_Density_Functional
(Vertridine-Stimulated influx of sodium channels in Neocortical neurons)c LogP (XLogP3 algorithm, Cheng et al., 2007) (—)-Cocaine H 326 ± 106 513 ± 143
List_of_cocaine_analogues
Pharmaceutical compound
between SKF101468 and SKF89124 is shown in Fig. 13. The hydroxy group reduces logP and increases PSA, the influences of the hydroxy group makes logBB decrease
7-Hydroxyropinirole
Type of medication applied to the skin
formulations must present a broad spectrum of bactericidal activity, low logP, compatibility with other excipients, stability, and effectiveness over a
Topical_cream_formulation
Model for designing parallel algorithms
computing Concurrency (computer science) Dataflow programming Grid computing LogP machine Parallel computing Parallel programming model Leslie G. Valiant,
Bulk_synchronous_parallel
Chemical compound
ester of estradiol. The experimental octanol/water partition coefficient (logP) of estradiol cypionate is 6.9. Estradiol cypionate was patented by Upjohn
Estradiol_cypionate
Keeper solvent M.W. (g/mol) Boiling point (˚C) Vapor pressure (Pa) LogP toluene 92.14 110.6 3786.4 2.73 dimethylformamide (DMF) 73.10 153.0 516.0 −1.01
Keeper_(chemistry)
Chemical compound
colourless crystalline solid. The melting point is around 166.5-167.0 °C. The logP is 2.22.[clarification needed] Cyanazine is not very reactive in neutral
Cyanazine
Chemical compound
ester of estradiol. The experimental octanol/water partition coefficient (logP) of estradiol dipropionate is 4.9. Estradiol dipropionate was first synthesized
Estradiol_dipropionate
Triazolobenzodiazepine drug
Interactive image Melting point 171–172.5 °C (339.8–342.5 °F) Solubility in water LogP: 4.16 Soluble in dichloromethane and methanol Salt (mesylate) soluble in
Adinazolam
Undergraduate student body in Vallejo, CA, U.S.
Corps of Cadets Logp
California Maritime Academy Corps of Cadets
California_Maritime_Academy_Corps_of_Cadets
Chemical compound
3-benzoate 17β-n-butyrate. The experimental octanol/water partition coefficient (logP) of EBB is 6.3. EBB, along with a variety of other estradiol esters, was
Estradiol_benzoate_butyrate
Chemical compound
exposure, after rapid deacetylation.) 2′-Acetoxycocaine has a closer to optimum LogP (a square value of 2) for blood–brain barrier penetration (cocaine being
2′-Acetoxycocaine
Pharmaceutical compound
to be able to cross the blood–brain barrier. As an example, its predicted logP is 3.3 to 3.7. In accordance with predictions, compound showed clear centrally
Compound 22 (TAAR1 antagonist)
Compound_22_(TAAR1_antagonist)
Previtamin
7e-14 mg/L at 25°C, indicating very low solubility in water. Its predicted logP values range from 9.66 to 15.27, highlighting its lipophilic nature. In biological
Α-Zeacarotene
Chemical compound
Physical state Solid Solubility Soluble in ethanol, methanol, DMSO, and water Absorption maximum 233, 258, 329, 438 nm Melting point 173-176 °C logP 3.74
Hycanthone
American chemist (1952–2016)
Albert Leo to work on the prediction of octanol-water partition coefficient (LogP) for molecules, which resulted in the software, cLogP, in 1983. The first
David_Weininger
Chemical compound
ester of estradiol. The experimental octanol/water partition coefficient (logP) of estradiol benzoate is 4.7. Estradiol benzoate was one of the first estrogens
Estradiol_benzoate
Chemical compound
conjugates include dehydroepiandrosterone sulfate and pregnenolone sulfate. The logP of E1S is 1.4. E1S is produced via estrogen sulfotransferases from the peripheral
Estrone_sulfate
41861; 15.21528 (Ottenschlag Airport (Ottenschlag)) Pinkafeld Burgenland LOGP Pinkafeld Airport 47°23′12″N 016°06′46″E / 47.38667°N 16.11278°E / 47
List_of_airports_in_Austria
Approximate quantum chemistry model
ISSN 1547-5905. S2CID 103011443. "COSMO-RS: predict activity coefficients, logP, VLE from DFT data". Software for Chemistry & Materials. Retrieved 6 November
COSMO-RS
Chemical compound
ester of estradiol. The experimental octanol/water partition coefficient (logP) of estradiol acetate is 4.2. Estradiol acetate is relatively recent to the
Estradiol_acetate
Chemical compound
than cocaine when administered to mice (likely owing to it having a higher LogP: 2.89 than that of cocaine: 2.62) Note however that the compound 2′-Acetoxycocaine
Salicylmethylecgonine
Chemical compound
centers. Both botryococcane and botryococcenes are non-polar compounds with a logP (Measure of solubility in the non-polar solvent octanol) of approximately
Botryococcenes
LOGP
LOGP
LOGP
LOGP
LOGP
LOGP
LOGP
LOGP
LOGP