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LBX1

  • LBX1

    • Protein-coding gene in the species Homo sapiens

    Transcription factor LBX1 is a protein that in humans is encoded by the LBX1 gene. This gene and the orthologous mouse gene were found by their homology

    LBX1

    LBX1

    LBX1

  • Myogenesis

    • Formation of muscular tissue, particularly during embryonic development

    Associated Genetic Factors: c-Met/HGF and LBX1 Mutations in these genetic factors causes a lack of migration. LBX1 is responsible for the development and

    Myogenesis

    Myogenesis

    Myogenesis

  • Adolescent idiopathic scoliosis

    • Medical condition

    studies is called rs11190870. This SNP was located in an area 75 kb 3' of the LBX1 gene, an intergenic area that also happened to be close to a separate gene

    Adolescent idiopathic scoliosis

    Adolescent idiopathic scoliosis

    Adolescent_idiopathic_scoliosis

  • SOX17

    • Protein-coding gene in the species Homo sapiens

    BARHL1 BARHL2 BARX1 BARX2 BSX DBX 1 2 DLX 1 2 3 4 5 6 EMX 1 2 EN 1 2 HHEX HLX LBX1 LBX2 MSX 1 2 NANOG NKX 2-1 2-2 2-3 2-5 2-9 3-1 3-2 HMX1 HMX2 HMX3 6-1 6-2

    SOX17

    SOX17

    SOX17

  • ATF3

    • Protein-coding gene in humans

    BARHL1 BARHL2 BARX1 BARX2 BSX DBX 1 2 DLX 1 2 3 4 5 6 EMX 1 2 EN 1 2 HHEX HLX LBX1 LBX2 MSX 1 2 NANOG NKX 2-1 2-2 2-3 2-5 2-9 3-1 3-2 HMX1 HMX2 HMX3 6-1 6-2

    ATF3

    ATF3

    ATF3

  • N-Myc

    • Protein-coding gene in the species Homo sapiens

    BARHL1 BARHL2 BARX1 BARX2 BSX DBX 1 2 DLX 1 2 3 4 5 6 EMX 1 2 EN 1 2 HHEX HLX LBX1 LBX2 MSX 1 2 NANOG NKX 2-1 2-2 2-3 2-5 2-9 3-1 3-2 HMX1 HMX2 HMX3 6-1 6-2

    N-Myc

    N-Myc

    N-Myc

  • TRPS1

    • Protein-coding gene in the species Homo sapiens

    BARHL1 BARHL2 BARX1 BARX2 BSX DBX 1 2 DLX 1 2 3 4 5 6 EMX 1 2 EN 1 2 HHEX HLX LBX1 LBX2 MSX 1 2 NANOG NKX 2-1 2-2 2-3 2-5 2-9 3-1 3-2 HMX1 HMX2 HMX3 6-1 6-2

    TRPS1

    TRPS1

    TRPS1

  • GLI2

    • Protein-coding gene in the species Homo sapiens

    BARHL1 BARHL2 BARX1 BARX2 BSX DBX 1 2 DLX 1 2 3 4 5 6 EMX 1 2 EN 1 2 HHEX HLX LBX1 LBX2 MSX 1 2 NANOG NKX 2-1 2-2 2-3 2-5 2-9 3-1 3-2 HMX1 HMX2 HMX3 6-1 6-2

    GLI2

    GLI2

    GLI2

  • SOX18

    • Protein-coding gene in the species Homo sapiens

    BARHL1 BARHL2 BARX1 BARX2 BSX DBX 1 2 DLX 1 2 3 4 5 6 EMX 1 2 EN 1 2 HHEX HLX LBX1 LBX2 MSX 1 2 NANOG NKX 2-1 2-2 2-3 2-5 2-9 3-1 3-2 HMX1 HMX2 HMX3 6-1 6-2

    SOX18

    SOX18

    SOX18

  • GTF2H1

    • Protein-coding gene in the species Homo sapiens

    BARHL1 BARHL2 BARX1 BARX2 BSX DBX 1 2 DLX 1 2 3 4 5 6 EMX 1 2 EN 1 2 HHEX HLX LBX1 LBX2 MSX 1 2 NANOG NKX 2-1 2-2 2-3 2-5 2-9 3-1 3-2 HMX1 HMX2 HMX3 6-1 6-2

    GTF2H1

    GTF2H1

    GTF2H1

  • ZNF274

    • Protein-coding gene in the species Homo sapiens

    BARHL1 BARHL2 BARX1 BARX2 BSX DBX 1 2 DLX 1 2 3 4 5 6 EMX 1 2 EN 1 2 HHEX HLX LBX1 LBX2 MSX 1 2 NANOG NKX 2-1 2-2 2-3 2-5 2-9 3-1 3-2 HMX1 HMX2 HMX3 6-1 6-2

    ZNF274

    ZNF274

    ZNF274

  • Receptor (biochemistry)

    • Protein molecule receiving signals for a cell

    BARHL1 BARHL2 BARX1 BARX2 BSX DBX 1 2 DLX 1 2 3 4 5 6 EMX 1 2 EN 1 2 HHEX HLX LBX1 LBX2 MSX 1 2 NANOG NKX 2-1 2-2 2-3 2-5 2-9 3-1 3-2 HMX1 HMX2 HMX3 6-1 6-2

    Receptor (biochemistry)

    Receptor (biochemistry)

    Receptor_(biochemistry)

  • ASCL1

    • Protein-coding gene in humans

    BARHL1 BARHL2 BARX1 BARX2 BSX DBX 1 2 DLX 1 2 3 4 5 6 EMX 1 2 EN 1 2 HHEX HLX LBX1 LBX2 MSX 1 2 NANOG NKX 2-1 2-2 2-3 2-5 2-9 3-1 3-2 HMX1 HMX2 HMX3 6-1 6-2

    ASCL1

    ASCL1

    ASCL1

  • Receptor tyrosine kinase

    • Class of enzymes

    during myogenesis. A lack of c-met disrupts secondary myogenesis and—as in LBX1—prevents the formation of limb musculature. This local action of FGFs (Fibroblast

    Receptor tyrosine kinase

    Receptor tyrosine kinase

    Receptor_tyrosine_kinase

  • Sex-determining region Y protein

    • Protein that initiates male sex determination in therian mammals

    BARHL1 BARHL2 BARX1 BARX2 BSX DBX 1 2 DLX 1 2 3 4 5 6 EMX 1 2 EN 1 2 HHEX HLX LBX1 LBX2 MSX 1 2 NANOG NKX 2-1 2-2 2-3 2-5 2-9 3-1 3-2 HMX1 HMX2 HMX3 6-1 6-2

    Sex-determining region Y protein

    Sex-determining region Y protein

    Sex-determining_region_Y_protein

  • Ultraconserved element

    • Sections of the genome experiencing minimal changes across species

    Ogilvie JW, Albertsen HM, Ward K (2015-02-12). Fang S (ed.). "Haplotypes at LBX1 have distinct inheritance patterns with opposite effects in adolescent idiopathic

    Ultraconserved element

    Ultraconserved_element

  • EPAS1

    • Protein found in humans

    BARHL1 BARHL2 BARX1 BARX2 BSX DBX 1 2 DLX 1 2 3 4 5 6 EMX 1 2 EN 1 2 HHEX HLX LBX1 LBX2 MSX 1 2 NANOG NKX 2-1 2-2 2-3 2-5 2-9 3-1 3-2 HMX1 HMX2 HMX3 6-1 6-2

    EPAS1

    EPAS1

    EPAS1

  • Zinc finger

    • Small structural protein motif found mostly in transcriptional proteins

    BARHL1 BARHL2 BARX1 BARX2 BSX DBX 1 2 DLX 1 2 3 4 5 6 EMX 1 2 EN 1 2 HHEX HLX LBX1 LBX2 MSX 1 2 NANOG NKX 2-1 2-2 2-3 2-5 2-9 3-1 3-2 HMX1 HMX2 HMX3 6-1 6-2

    Zinc finger

    Zinc finger

    Zinc_finger

  • ZNF300

    • Human protein-coding gene

    BARHL1 BARHL2 BARX1 BARX2 BSX DBX 1 2 DLX 1 2 3 4 5 6 EMX 1 2 EN 1 2 HHEX HLX LBX1 LBX2 MSX 1 2 NANOG NKX 2-1 2-2 2-3 2-5 2-9 3-1 3-2 HMX1 HMX2 HMX3 6-1 6-2

    ZNF300

    ZNF300

    ZNF300

  • Retinoic acid receptor alpha

    • Protein found in humans

    BARHL1 BARHL2 BARX1 BARX2 BSX DBX 1 2 DLX 1 2 3 4 5 6 EMX 1 2 EN 1 2 HHEX HLX LBX1 LBX2 MSX 1 2 NANOG NKX 2-1 2-2 2-3 2-5 2-9 3-1 3-2 HMX1 HMX2 HMX3 6-1 6-2

    Retinoic acid receptor alpha

    Retinoic acid receptor alpha

    Retinoic_acid_receptor_alpha

  • NF-κB

    • Family of transcription factor protein complexes

    BARHL1 BARHL2 BARX1 BARX2 BSX DBX 1 2 DLX 1 2 3 4 5 6 EMX 1 2 EN 1 2 HHEX HLX LBX1 LBX2 MSX 1 2 NANOG NKX 2-1 2-2 2-3 2-5 2-9 3-1 3-2 HMX1 HMX2 HMX3 6-1 6-2

    NF-κB

    NF-κB

    NF-κB

  • CREB

    • Class of proteins

    BARHL1 BARHL2 BARX1 BARX2 BSX DBX 1 2 DLX 1 2 3 4 5 6 EMX 1 2 EN 1 2 HHEX HLX LBX1 LBX2 MSX 1 2 NANOG NKX 2-1 2-2 2-3 2-5 2-9 3-1 3-2 HMX1 HMX2 HMX3 6-1 6-2

    CREB

    CREB

    CREB

  • Peroxisome proliferator-activated receptor alpha

    • Nuclear receptor protein found in humans

    BARHL1 BARHL2 BARX1 BARX2 BSX DBX 1 2 DLX 1 2 3 4 5 6 EMX 1 2 EN 1 2 HHEX HLX LBX1 LBX2 MSX 1 2 NANOG NKX 2-1 2-2 2-3 2-5 2-9 3-1 3-2 HMX1 HMX2 HMX3 6-1 6-2

    Peroxisome proliferator-activated receptor alpha

    Peroxisome proliferator-activated receptor alpha

    Peroxisome_proliferator-activated_receptor_alpha

  • Hypoxia-inducible factor

    • Protein that responds to low oxygen

    BARHL1 BARHL2 BARX1 BARX2 BSX DBX 1 2 DLX 1 2 3 4 5 6 EMX 1 2 EN 1 2 HHEX HLX LBX1 LBX2 MSX 1 2 NANOG NKX 2-1 2-2 2-3 2-5 2-9 3-1 3-2 HMX1 HMX2 HMX3 6-1 6-2

    Hypoxia-inducible factor

    Hypoxia-inducible_factor

  • Protein c-Fos

    • Mammalian protein found in Homo sapiens

    BARHL1 BARHL2 BARX1 BARX2 BSX DBX 1 2 DLX 1 2 3 4 5 6 EMX 1 2 EN 1 2 HHEX HLX LBX1 LBX2 MSX 1 2 NANOG NKX 2-1 2-2 2-3 2-5 2-9 3-1 3-2 HMX1 HMX2 HMX3 6-1 6-2

    Protein c-Fos

    Protein c-Fos

    Protein_c-Fos

  • Estrogen receptor

    • Proteins activated by the hormone estrogen

    BARHL1 BARHL2 BARX1 BARX2 BSX DBX 1 2 DLX 1 2 3 4 5 6 EMX 1 2 EN 1 2 HHEX HLX LBX1 LBX2 MSX 1 2 NANOG NKX 2-1 2-2 2-3 2-5 2-9 3-1 3-2 HMX1 HMX2 HMX3 6-1 6-2

    Estrogen receptor

    Estrogen receptor

    Estrogen_receptor

  • Sigma factor

    • Protein needed for initiation of transcription in prokaryotes

    BARHL1 BARHL2 BARX1 BARX2 BSX DBX 1 2 DLX 1 2 3 4 5 6 EMX 1 2 EN 1 2 HHEX HLX LBX1 LBX2 MSX 1 2 NANOG NKX 2-1 2-2 2-3 2-5 2-9 3-1 3-2 HMX1 HMX2 HMX3 6-1 6-2

    Sigma factor

    Sigma_factor

  • Peroxisome proliferator-activated receptor gamma

    • Nuclear receptor protein found in humans

    BARHL1 BARHL2 BARX1 BARX2 BSX DBX 1 2 DLX 1 2 3 4 5 6 EMX 1 2 EN 1 2 HHEX HLX LBX1 LBX2 MSX 1 2 NANOG NKX 2-1 2-2 2-3 2-5 2-9 3-1 3-2 HMX1 HMX2 HMX3 6-1 6-2

    Peroxisome proliferator-activated receptor gamma

    Peroxisome proliferator-activated receptor gamma

    Peroxisome_proliferator-activated_receptor_gamma

  • Myc

    • Family of regulator genes

    BARHL1 BARHL2 BARX1 BARX2 BSX DBX 1 2 DLX 1 2 3 4 5 6 EMX 1 2 EN 1 2 HHEX HLX LBX1 LBX2 MSX 1 2 NANOG NKX 2-1 2-2 2-3 2-5 2-9 3-1 3-2 HMX1 HMX2 HMX3 6-1 6-2

    Myc

    Myc

  • List of human transcription factors

    • specific TF according to literature or domain structure – No motif [479] LBX1 ENSG00000138136 Homeodomain Known motif – High-throughput in vitro [480]

    List of human transcription factors

    List_of_human_transcription_factors

  • Glucocorticoid receptor

    • Receptor to which cortisol and other glucocorticoids bind

    BARHL1 BARHL2 BARX1 BARX2 BSX DBX 1 2 DLX 1 2 3 4 5 6 EMX 1 2 EN 1 2 HHEX HLX LBX1 LBX2 MSX 1 2 NANOG NKX 2-1 2-2 2-3 2-5 2-9 3-1 3-2 HMX1 HMX2 HMX3 6-1 6-2

    Glucocorticoid receptor

    Glucocorticoid receptor

    Glucocorticoid_receptor

  • SPI1

    • Protein-coding gene in the species Homo sapiens

    BARHL1 BARHL2 BARX1 BARX2 BSX DBX 1 2 DLX 1 2 3 4 5 6 EMX 1 2 EN 1 2 HHEX HLX LBX1 LBX2 MSX 1 2 NANOG NKX 2-1 2-2 2-3 2-5 2-9 3-1 3-2 HMX1 HMX2 HMX3 6-1 6-2

    SPI1

    SPI1

    SPI1

  • STAT3

    • Protein-coding gene in humans

    BARHL1 BARHL2 BARX1 BARX2 BSX DBX 1 2 DLX 1 2 3 4 5 6 EMX 1 2 EN 1 2 HHEX HLX LBX1 LBX2 MSX 1 2 NANOG NKX 2-1 2-2 2-3 2-5 2-9 3-1 3-2 HMX1 HMX2 HMX3 6-1 6-2

    STAT3

    STAT3

    STAT3

  • Twist-related protein 2

    • Protein-coding gene in the species Homo sapiens

    BARHL1 BARHL2 BARX1 BARX2 BSX DBX 1 2 DLX 1 2 3 4 5 6 EMX 1 2 EN 1 2 HHEX HLX LBX1 LBX2 MSX 1 2 NANOG NKX 2-1 2-2 2-3 2-5 2-9 3-1 3-2 HMX1 HMX2 HMX3 6-1 6-2

    Twist-related protein 2

    Twist-related protein 2

    Twist-related_protein_2

  • Androgen receptor

    • Mammalian protein found in humans

    BARHL1 BARHL2 BARX1 BARX2 BSX DBX 1 2 DLX 1 2 3 4 5 6 EMX 1 2 EN 1 2 HHEX HLX LBX1 LBX2 MSX 1 2 NANOG NKX 2-1 2-2 2-3 2-5 2-9 3-1 3-2 HMX1 HMX2 HMX3 6-1 6-2

    Androgen receptor

    Androgen receptor

    Androgen_receptor

  • Estrogen receptor alpha

    • Protein-coding gene in the species Homo sapiens

    BARHL1 BARHL2 BARX1 BARX2 BSX DBX 1 2 DLX 1 2 3 4 5 6 EMX 1 2 EN 1 2 HHEX HLX LBX1 LBX2 MSX 1 2 NANOG NKX 2-1 2-2 2-3 2-5 2-9 3-1 3-2 HMX1 HMX2 HMX3 6-1 6-2

    Estrogen receptor alpha

    Estrogen receptor alpha

    Estrogen_receptor_alpha

  • MADS-box

    • Protein family

    BARHL1 BARHL2 BARX1 BARX2 BSX DBX 1 2 DLX 1 2 3 4 5 6 EMX 1 2 EN 1 2 HHEX HLX LBX1 LBX2 MSX 1 2 NANOG NKX 2-1 2-2 2-3 2-5 2-9 3-1 3-2 HMX1 HMX2 HMX3 6-1 6-2

    MADS-box

    MADS-box

  • GAI (Arabidopsis thaliana gene)

    • Gene in Arabidopsis thaliana

    BARHL1 BARHL2 BARX1 BARX2 BSX DBX 1 2 DLX 1 2 3 4 5 6 EMX 1 2 EN 1 2 HHEX HLX LBX1 LBX2 MSX 1 2 NANOG NKX 2-1 2-2 2-3 2-5 2-9 3-1 3-2 HMX1 HMX2 HMX3 6-1 6-2

    GAI (Arabidopsis thaliana gene)

    GAI_(Arabidopsis_thaliana_gene)

  • Zbtb7

    • Mammalian protein found in Homo sapiens

    BARHL1 BARHL2 BARX1 BARX2 BSX DBX 1 2 DLX 1 2 3 4 5 6 EMX 1 2 EN 1 2 HHEX HLX LBX1 LBX2 MSX 1 2 NANOG NKX 2-1 2-2 2-3 2-5 2-9 3-1 3-2 HMX1 HMX2 HMX3 6-1 6-2

    Zbtb7

    Zbtb7

  • PROX1

    • Protein-coding gene in the species Homo sapiens

    BARHL1 BARHL2 BARX1 BARX2 BSX DBX 1 2 DLX 1 2 3 4 5 6 EMX 1 2 EN 1 2 HHEX HLX LBX1 LBX2 MSX 1 2 NANOG NKX 2-1 2-2 2-3 2-5 2-9 3-1 3-2 HMX1 HMX2 HMX3 6-1 6-2

    PROX1

    PROX1

    PROX1

  • Homeobox

    • DNA pattern affecting anatomy development

    BARHL2; BARX1, BARX2; BSX; DBX1, DBX2; EMX1, EMX2; EN1, EN2; HHEX; HLX1; LBX1, LBX2; MSX1, MSX2; NANOG; NOTO; TLX1, TLX2, TLX3; TSHZ1, TSHZ2, TSHZ3; VAX1

    Homeobox

    Homeobox

    Homeobox

  • Retinoid X receptor

    • Genes on human chromosome 9

    BARHL1 BARHL2 BARX1 BARX2 BSX DBX 1 2 DLX 1 2 3 4 5 6 EMX 1 2 EN 1 2 HHEX HLX LBX1 LBX2 MSX 1 2 NANOG NKX 2-1 2-2 2-3 2-5 2-9 3-1 3-2 HMX1 HMX2 HMX3 6-1 6-2

    Retinoid X receptor

    Retinoid_X_receptor

  • PRDM16

    • Protein-coding gene in the species Homo sapiens

    BARHL1 BARHL2 BARX1 BARX2 BSX DBX 1 2 DLX 1 2 3 4 5 6 EMX 1 2 EN 1 2 HHEX HLX LBX1 LBX2 MSX 1 2 NANOG NKX 2-1 2-2 2-3 2-5 2-9 3-1 3-2 HMX1 HMX2 HMX3 6-1 6-2

    PRDM16

    PRDM16

    PRDM16

  • FOSB

    • Protein

    BARHL1 BARHL2 BARX1 BARX2 BSX DBX 1 2 DLX 1 2 3 4 5 6 EMX 1 2 EN 1 2 HHEX HLX LBX1 LBX2 MSX 1 2 NANOG NKX 2-1 2-2 2-3 2-5 2-9 3-1 3-2 HMX1 HMX2 HMX3 6-1 6-2

    FOSB

    FOSB

    FOSB

  • GATA1

    • Protein-coding gene in humans

    BARHL1 BARHL2 BARX1 BARX2 BSX DBX 1 2 DLX 1 2 3 4 5 6 EMX 1 2 EN 1 2 HHEX HLX LBX1 LBX2 MSX 1 2 NANOG NKX 2-1 2-2 2-3 2-5 2-9 3-1 3-2 HMX1 HMX2 HMX3 6-1 6-2

    GATA1

    GATA1

    GATA1

  • Y-box-binding protein 3

    • Protein-coding gene in humans

    BARHL1 BARHL2 BARX1 BARX2 BSX DBX 1 2 DLX 1 2 3 4 5 6 EMX 1 2 EN 1 2 HHEX HLX LBX1 LBX2 MSX 1 2 NANOG NKX 2-1 2-2 2-3 2-5 2-9 3-1 3-2 HMX1 HMX2 HMX3 6-1 6-2

    Y-box-binding protein 3

    Y-box-binding protein 3

    Y-box-binding_protein_3

  • LHX3

    • Protein-coding gene in the species Homo sapiens

    BARHL1 BARHL2 BARX1 BARX2 BSX DBX 1 2 DLX 1 2 3 4 5 6 EMX 1 2 EN 1 2 HHEX HLX LBX1 LBX2 MSX 1 2 NANOG NKX 2-1 2-2 2-3 2-5 2-9 3-1 3-2 HMX1 HMX2 HMX3 6-1 6-2

    LHX3

    LHX3

    LHX3

  • ELK3

    • Protein-coding gene in humans

    BARHL1 BARHL2 BARX1 BARX2 BSX DBX 1 2 DLX 1 2 3 4 5 6 EMX 1 2 EN 1 2 HHEX HLX LBX1 LBX2 MSX 1 2 NANOG NKX 2-1 2-2 2-3 2-5 2-9 3-1 3-2 HMX1 HMX2 HMX3 6-1 6-2

    ELK3

    ELK3

    ELK3

  • TCF4

    • Protein-coding gene in the species Homo sapiens

    BARHL1 BARHL2 BARX1 BARX2 BSX DBX 1 2 DLX 1 2 3 4 5 6 EMX 1 2 EN 1 2 HHEX HLX LBX1 LBX2 MSX 1 2 NANOG NKX 2-1 2-2 2-3 2-5 2-9 3-1 3-2 HMX1 HMX2 HMX3 6-1 6-2

    TCF4

    TCF4

    TCF4

  • SOX4

    • Protein-coding gene in the species Homo sapiens

    BARHL1 BARHL2 BARX1 BARX2 BSX DBX 1 2 DLX 1 2 3 4 5 6 EMX 1 2 EN 1 2 HHEX HLX LBX1 LBX2 MSX 1 2 NANOG NKX 2-1 2-2 2-3 2-5 2-9 3-1 3-2 HMX1 HMX2 HMX3 6-1 6-2

    SOX4

    SOX4

    SOX4

  • Sterol regulatory element–binding protein 2

    • Protein-coding gene in the species Homo sapiens

    BARHL1 BARHL2 BARX1 BARX2 BSX DBX 1 2 DLX 1 2 3 4 5 6 EMX 1 2 EN 1 2 HHEX HLX LBX1 LBX2 MSX 1 2 NANOG NKX 2-1 2-2 2-3 2-5 2-9 3-1 3-2 HMX1 HMX2 HMX3 6-1 6-2

    Sterol regulatory element–binding protein 2

    Sterol regulatory element–binding protein 2

    Sterol_regulatory_element–binding_protein_2

  • SATB2

    • Protein-coding gene in the species Homo sapiens

    BARHL1 BARHL2 BARX1 BARX2 BSX DBX 1 2 DLX 1 2 3 4 5 6 EMX 1 2 EN 1 2 HHEX HLX LBX1 LBX2 MSX 1 2 NANOG NKX 2-1 2-2 2-3 2-5 2-9 3-1 3-2 HMX1 HMX2 HMX3 6-1 6-2

    SATB2

    SATB2

    SATB2

  • XBP1

    • Protein-coding gene in the species Homo sapiens

    BARHL1 BARHL2 BARX1 BARX2 BSX DBX 1 2 DLX 1 2 3 4 5 6 EMX 1 2 EN 1 2 HHEX HLX LBX1 LBX2 MSX 1 2 NANOG NKX 2-1 2-2 2-3 2-5 2-9 3-1 3-2 HMX1 HMX2 HMX3 6-1 6-2

    XBP1

    XBP1

    XBP1

  • Winged-helix transcription factors

    • Family of proteins

    BARHL1 BARHL2 BARX1 BARX2 BSX DBX 1 2 DLX 1 2 3 4 5 6 EMX 1 2 EN 1 2 HHEX HLX LBX1 LBX2 MSX 1 2 NANOG NKX 2-1 2-2 2-3 2-5 2-9 3-1 3-2 HMX1 HMX2 HMX3 6-1 6-2

    Winged-helix transcription factors

    Winged-helix transcription factors

    Winged-helix_transcription_factors

  • ETS variant 5

    • Protein-coding gene in the species Homo sapiens

    BARHL1 BARHL2 BARX1 BARX2 BSX DBX 1 2 DLX 1 2 3 4 5 6 EMX 1 2 EN 1 2 HHEX HLX LBX1 LBX2 MSX 1 2 NANOG NKX 2-1 2-2 2-3 2-5 2-9 3-1 3-2 HMX1 HMX2 HMX3 6-1 6-2

    ETS variant 5

    ETS variant 5

    ETS_variant_5

  • STAT5

    • Protein family

    BARHL1 BARHL2 BARX1 BARX2 BSX DBX 1 2 DLX 1 2 3 4 5 6 EMX 1 2 EN 1 2 HHEX HLX LBX1 LBX2 MSX 1 2 NANOG NKX 2-1 2-2 2-3 2-5 2-9 3-1 3-2 HMX1 HMX2 HMX3 6-1 6-2

    STAT5

    STAT5

    STAT5

  • FOXP1

    • Protein-coding gene in the species Homo sapiens

    BARHL1 BARHL2 BARX1 BARX2 BSX DBX 1 2 DLX 1 2 3 4 5 6 EMX 1 2 EN 1 2 HHEX HLX LBX1 LBX2 MSX 1 2 NANOG NKX 2-1 2-2 2-3 2-5 2-9 3-1 3-2 HMX1 HMX2 HMX3 6-1 6-2

    FOXP1

    FOXP1

    FOXP1

  • CEBPA

    • Protein-coding gene in humans

    BARHL1 BARHL2 BARX1 BARX2 BSX DBX 1 2 DLX 1 2 3 4 5 6 EMX 1 2 EN 1 2 HHEX HLX LBX1 LBX2 MSX 1 2 NANOG NKX 2-1 2-2 2-3 2-5 2-9 3-1 3-2 HMX1 HMX2 HMX3 6-1 6-2

    CEBPA

    CEBPA

    CEBPA

  • SOX10

    • Transcription factor gene of the SOX family

    BARHL1 BARHL2 BARX1 BARX2 BSX DBX 1 2 DLX 1 2 3 4 5 6 EMX 1 2 EN 1 2 HHEX HLX LBX1 LBX2 MSX 1 2 NANOG NKX 2-1 2-2 2-3 2-5 2-9 3-1 3-2 HMX1 HMX2 HMX3 6-1 6-2

    SOX10

    SOX10

    SOX10

  • MYC

    • Protein-coding gene in the species Homo sapiens

    BARHL1 BARHL2 BARX1 BARX2 BSX DBX 1 2 DLX 1 2 3 4 5 6 EMX 1 2 EN 1 2 HHEX HLX LBX1 LBX2 MSX 1 2 NANOG NKX 2-1 2-2 2-3 2-5 2-9 3-1 3-2 HMX1 HMX2 HMX3 6-1 6-2

    MYC

    MYC

    MYC

  • Heterochromatin protein 1

    • Protein family

    BARHL1 BARHL2 BARX1 BARX2 BSX DBX 1 2 DLX 1 2 3 4 5 6 EMX 1 2 EN 1 2 HHEX HLX LBX1 LBX2 MSX 1 2 NANOG NKX 2-1 2-2 2-3 2-5 2-9 3-1 3-2 HMX1 HMX2 HMX3 6-1 6-2

    Heterochromatin protein 1

    Heterochromatin_protein_1

  • PRDM1

    • Protein-coding gene in the species Homo sapiens

    BARHL1 BARHL2 BARX1 BARX2 BSX DBX 1 2 DLX 1 2 3 4 5 6 EMX 1 2 EN 1 2 HHEX HLX LBX1 LBX2 MSX 1 2 NANOG NKX 2-1 2-2 2-3 2-5 2-9 3-1 3-2 HMX1 HMX2 HMX3 6-1 6-2

    PRDM1

    PRDM1

    PRDM1

  • High-mobility group

    • Group of proteins

    BARHL1 BARHL2 BARX1 BARX2 BSX DBX 1 2 DLX 1 2 3 4 5 6 EMX 1 2 EN 1 2 HHEX HLX LBX1 LBX2 MSX 1 2 NANOG NKX 2-1 2-2 2-3 2-5 2-9 3-1 3-2 HMX1 HMX2 HMX3 6-1 6-2

    High-mobility group

    High-mobility_group

  • Aryl hydrocarbon receptor

    • Vertebrate receptor protein and transcription factor

    BARHL1 BARHL2 BARX1 BARX2 BSX DBX 1 2 DLX 1 2 3 4 5 6 EMX 1 2 EN 1 2 HHEX HLX LBX1 LBX2 MSX 1 2 NANOG NKX 2-1 2-2 2-3 2-5 2-9 3-1 3-2 HMX1 HMX2 HMX3 6-1 6-2

    Aryl hydrocarbon receptor

    Aryl hydrocarbon receptor

    Aryl_hydrocarbon_receptor

  • Retinoic acid receptor

    • Type of nuclear receptor

    BARHL1 BARHL2 BARX1 BARX2 BSX DBX 1 2 DLX 1 2 3 4 5 6 EMX 1 2 EN 1 2 HHEX HLX LBX1 LBX2 MSX 1 2 NANOG NKX 2-1 2-2 2-3 2-5 2-9 3-1 3-2 HMX1 HMX2 HMX3 6-1 6-2

    Retinoic acid receptor

    Retinoic acid receptor

    Retinoic_acid_receptor

  • E2F

    • Family of transcription factors

    BARHL1 BARHL2 BARX1 BARX2 BSX DBX 1 2 DLX 1 2 3 4 5 6 EMX 1 2 EN 1 2 HHEX HLX LBX1 LBX2 MSX 1 2 NANOG NKX 2-1 2-2 2-3 2-5 2-9 3-1 3-2 HMX1 HMX2 HMX3 6-1 6-2

    E2F

    E2F

  • CCAAT-enhancer-binding proteins

    • Protein family

    BARHL1 BARHL2 BARX1 BARX2 BSX DBX 1 2 DLX 1 2 3 4 5 6 EMX 1 2 EN 1 2 HHEX HLX LBX1 LBX2 MSX 1 2 NANOG NKX 2-1 2-2 2-3 2-5 2-9 3-1 3-2 HMX1 HMX2 HMX3 6-1 6-2

    CCAAT-enhancer-binding proteins

    CCAAT-enhancer-binding proteins

    CCAAT-enhancer-binding_proteins

  • General transcription factor

    • Class of protein transcription factors

    BARHL1 BARHL2 BARX1 BARX2 BSX DBX 1 2 DLX 1 2 3 4 5 6 EMX 1 2 EN 1 2 HHEX HLX LBX1 LBX2 MSX 1 2 NANOG NKX 2-1 2-2 2-3 2-5 2-9 3-1 3-2 HMX1 HMX2 HMX3 6-1 6-2

    General transcription factor

    General transcription factor

    General_transcription_factor

  • MNX1

    • Protein-coding gene in the species Homo sapiens

    BARHL1 BARHL2 BARX1 BARX2 BSX DBX 1 2 DLX 1 2 3 4 5 6 EMX 1 2 EN 1 2 HHEX HLX LBX1 LBX2 MSX 1 2 NANOG NKX 2-1 2-2 2-3 2-5 2-9 3-1 3-2 HMX1 HMX2 HMX3 6-1 6-2

    MNX1

    MNX1

    MNX1

  • Catabolite activator protein

    • Trans-acting transcriptional activator

    BARHL1 BARHL2 BARX1 BARX2 BSX DBX 1 2 DLX 1 2 3 4 5 6 EMX 1 2 EN 1 2 HHEX HLX LBX1 LBX2 MSX 1 2 NANOG NKX 2-1 2-2 2-3 2-5 2-9 3-1 3-2 HMX1 HMX2 HMX3 6-1 6-2

    Catabolite activator protein

    Catabolite activator protein

    Catabolite_activator_protein

  • SOX gene family

    • Family of transcription factors

    BARHL1 BARHL2 BARX1 BARX2 BSX DBX 1 2 DLX 1 2 3 4 5 6 EMX 1 2 EN 1 2 HHEX HLX LBX1 LBX2 MSX 1 2 NANOG NKX 2-1 2-2 2-3 2-5 2-9 3-1 3-2 HMX1 HMX2 HMX3 6-1 6-2

    SOX gene family

    SOX_gene_family

  • RBPJ

    • Protein-coding gene in the species Homo sapiens

    BARHL1 BARHL2 BARX1 BARX2 BSX DBX 1 2 DLX 1 2 3 4 5 6 EMX 1 2 EN 1 2 HHEX HLX LBX1 LBX2 MSX 1 2 NANOG NKX 2-1 2-2 2-3 2-5 2-9 3-1 3-2 HMX1 HMX2 HMX3 6-1 6-2

    RBPJ

    RBPJ

    RBPJ

  • BZIP domain

    • Protein domain

    BARHL1 BARHL2 BARX1 BARX2 BSX DBX 1 2 DLX 1 2 3 4 5 6 EMX 1 2 EN 1 2 HHEX HLX LBX1 LBX2 MSX 1 2 NANOG NKX 2-1 2-2 2-3 2-5 2-9 3-1 3-2 HMX1 HMX2 HMX3 6-1 6-2

    BZIP domain

    BZIP domain

    BZIP_domain

  • IRF3

    • Protein-coding gene in the species Homo sapiens

    BARHL1 BARHL2 BARX1 BARX2 BSX DBX 1 2 DLX 1 2 3 4 5 6 EMX 1 2 EN 1 2 HHEX HLX LBX1 LBX2 MSX 1 2 NANOG NKX 2-1 2-2 2-3 2-5 2-9 3-1 3-2 HMX1 HMX2 HMX3 6-1 6-2

    IRF3

    IRF3

    IRF3

  • T-box

    • Genes that affect limb and heart development

    BARHL1 BARHL2 BARX1 BARX2 BSX DBX 1 2 DLX 1 2 3 4 5 6 EMX 1 2 EN 1 2 HHEX HLX LBX1 LBX2 MSX 1 2 NANOG NKX 2-1 2-2 2-3 2-5 2-9 3-1 3-2 HMX1 HMX2 HMX3 6-1 6-2

    T-box

    T-box

    T-box

  • DAX1

    • Protein-coding gene in humans

    BARHL1 BARHL2 BARX1 BARX2 BSX DBX 1 2 DLX 1 2 3 4 5 6 EMX 1 2 EN 1 2 HHEX HLX LBX1 LBX2 MSX 1 2 NANOG NKX 2-1 2-2 2-3 2-5 2-9 3-1 3-2 HMX1 HMX2 HMX3 6-1 6-2

    DAX1

    DAX1

    DAX1

  • IRF5

    • Protein-coding gene in the species Homo sapiens

    BARHL1 BARHL2 BARX1 BARX2 BSX DBX 1 2 DLX 1 2 3 4 5 6 EMX 1 2 EN 1 2 HHEX HLX LBX1 LBX2 MSX 1 2 NANOG NKX 2-1 2-2 2-3 2-5 2-9 3-1 3-2 HMX1 HMX2 HMX3 6-1 6-2

    IRF5

    IRF5

    IRF5

  • Pregnane X receptor

    • Mammalian protein found in Homo sapiens

    BARHL1 BARHL2 BARX1 BARX2 BSX DBX 1 2 DLX 1 2 3 4 5 6 EMX 1 2 EN 1 2 HHEX HLX LBX1 LBX2 MSX 1 2 NANOG NKX 2-1 2-2 2-3 2-5 2-9 3-1 3-2 HMX1 HMX2 HMX3 6-1 6-2

    Pregnane X receptor

    Pregnane X receptor

    Pregnane_X_receptor

  • ZEB1

    • Protein-coding gene in the species Homo sapiens

    BARHL1 BARHL2 BARX1 BARX2 BSX DBX 1 2 DLX 1 2 3 4 5 6 EMX 1 2 EN 1 2 HHEX HLX LBX1 LBX2 MSX 1 2 NANOG NKX 2-1 2-2 2-3 2-5 2-9 3-1 3-2 HMX1 HMX2 HMX3 6-1 6-2

    ZEB1

    ZEB1

    ZEB1

  • DMRT1

    • Protein-coding gene in humans

    BARHL1 BARHL2 BARX1 BARX2 BSX DBX 1 2 DLX 1 2 3 4 5 6 EMX 1 2 EN 1 2 HHEX HLX LBX1 LBX2 MSX 1 2 NANOG NKX 2-1 2-2 2-3 2-5 2-9 3-1 3-2 HMX1 HMX2 HMX3 6-1 6-2

    DMRT1

    DMRT1

    DMRT1

  • NRF1

    • Protein-coding gene in the species Homo sapiens

    BARHL1 BARHL2 BARX1 BARX2 BSX DBX 1 2 DLX 1 2 3 4 5 6 EMX 1 2 EN 1 2 HHEX HLX LBX1 LBX2 MSX 1 2 NANOG NKX 2-1 2-2 2-3 2-5 2-9 3-1 3-2 HMX1 HMX2 HMX3 6-1 6-2

    NRF1

    NRF1

    NRF1

  • YY1

    • Transcriptional repressor protein

    BARHL1 BARHL2 BARX1 BARX2 BSX DBX 1 2 DLX 1 2 3 4 5 6 EMX 1 2 EN 1 2 HHEX HLX LBX1 LBX2 MSX 1 2 NANOG NKX 2-1 2-2 2-3 2-5 2-9 3-1 3-2 HMX1 HMX2 HMX3 6-1 6-2

    YY1

    YY1

    YY1

  • SMAD2

    • Protein found in humans

    BARHL1 BARHL2 BARX1 BARX2 BSX DBX 1 2 DLX 1 2 3 4 5 6 EMX 1 2 EN 1 2 HHEX HLX LBX1 LBX2 MSX 1 2 NANOG NKX 2-1 2-2 2-3 2-5 2-9 3-1 3-2 HMX1 HMX2 HMX3 6-1 6-2

    SMAD2

    SMAD2

    SMAD2

  • Serum response factor

    • Mammalian protein found in Homo sapiens

    BARHL1 BARHL2 BARX1 BARX2 BSX DBX 1 2 DLX 1 2 3 4 5 6 EMX 1 2 EN 1 2 HHEX HLX LBX1 LBX2 MSX 1 2 NANOG NKX 2-1 2-2 2-3 2-5 2-9 3-1 3-2 HMX1 HMX2 HMX3 6-1 6-2

    Serum response factor

    Serum response factor

    Serum_response_factor

  • TLX

    • Protein-coding gene in the species Homo sapiens

    BARHL1 BARHL2 BARX1 BARX2 BSX DBX 1 2 DLX 1 2 3 4 5 6 EMX 1 2 EN 1 2 HHEX HLX LBX1 LBX2 MSX 1 2 NANOG NKX 2-1 2-2 2-3 2-5 2-9 3-1 3-2 HMX1 HMX2 HMX3 6-1 6-2

    TLX

    TLX

    TLX

  • ZNF318

    • Protein-coding gene in humans

    BARHL1 BARHL2 BARX1 BARX2 BSX DBX 1 2 DLX 1 2 3 4 5 6 EMX 1 2 EN 1 2 HHEX HLX LBX1 LBX2 MSX 1 2 NANOG NKX 2-1 2-2 2-3 2-5 2-9 3-1 3-2 HMX1 HMX2 HMX3 6-1 6-2

    ZNF318

    ZNF318

    ZNF318

  • Retinoblastoma protein

    • Mammalian protein found in humans

    BARHL1 BARHL2 BARX1 BARX2 BSX DBX 1 2 DLX 1 2 3 4 5 6 EMX 1 2 EN 1 2 HHEX HLX LBX1 LBX2 MSX 1 2 NANOG NKX 2-1 2-2 2-3 2-5 2-9 3-1 3-2 HMX1 HMX2 HMX3 6-1 6-2

    Retinoblastoma protein

    Retinoblastoma protein

    Retinoblastoma_protein

  • NK2 homeobox 1

    • Mammalian protein found in Homo sapiens

    BARHL1 BARHL2 BARX1 BARX2 BSX DBX 1 2 DLX 1 2 3 4 5 6 EMX 1 2 EN 1 2 HHEX HLX LBX1 LBX2 MSX 1 2 NANOG NKX 2-1 2-2 2-3 2-5 2-9 3-1 3-2 HMX1 HMX2 HMX3 6-1 6-2

    NK2 homeobox 1

    NK2 homeobox 1

    NK2_homeobox_1

  • TATA-binding protein

    • Protein-coding gene in the species Homo sapiens

    BARHL1 BARHL2 BARX1 BARX2 BSX DBX 1 2 DLX 1 2 3 4 5 6 EMX 1 2 EN 1 2 HHEX HLX LBX1 LBX2 MSX 1 2 NANOG NKX 2-1 2-2 2-3 2-5 2-9 3-1 3-2 HMX1 HMX2 HMX3 6-1 6-2

    TATA-binding protein

    TATA-binding protein

    TATA-binding_protein

  • RAR-related orphan receptor gamma

    • Cellular receptor

    BARHL1 BARHL2 BARX1 BARX2 BSX DBX 1 2 DLX 1 2 3 4 5 6 EMX 1 2 EN 1 2 HHEX HLX LBX1 LBX2 MSX 1 2 NANOG NKX 2-1 2-2 2-3 2-5 2-9 3-1 3-2 HMX1 HMX2 HMX3 6-1 6-2

    RAR-related orphan receptor gamma

    RAR-related orphan receptor gamma

    RAR-related_orphan_receptor_gamma

  • PAX8

    • Mammalian protein found in humans

    BARHL1 BARHL2 BARX1 BARX2 BSX DBX 1 2 DLX 1 2 3 4 5 6 EMX 1 2 EN 1 2 HHEX HLX LBX1 LBX2 MSX 1 2 NANOG NKX 2-1 2-2 2-3 2-5 2-9 3-1 3-2 HMX1 HMX2 HMX3 6-1 6-2

    PAX8

    PAX8

    PAX8

  • ZNF202

    • Protein-coding gene in the species Homo sapiens

    BARHL1 BARHL2 BARX1 BARX2 BSX DBX 1 2 DLX 1 2 3 4 5 6 EMX 1 2 EN 1 2 HHEX HLX LBX1 LBX2 MSX 1 2 NANOG NKX 2-1 2-2 2-3 2-5 2-9 3-1 3-2 HMX1 HMX2 HMX3 6-1 6-2

    ZNF202

    ZNF202

    ZNF202

  • GATA4

    • Protein-coding gene in the species Homo sapiens

    BARHL1 BARHL2 BARX1 BARX2 BSX DBX 1 2 DLX 1 2 3 4 5 6 EMX 1 2 EN 1 2 HHEX HLX LBX1 LBX2 MSX 1 2 NANOG NKX 2-1 2-2 2-3 2-5 2-9 3-1 3-2 HMX1 HMX2 HMX3 6-1 6-2

    GATA4

    GATA4

    GATA4

  • HNF1A

    • Protein-coding gene in humans

    BARHL1 BARHL2 BARX1 BARX2 BSX DBX 1 2 DLX 1 2 3 4 5 6 EMX 1 2 EN 1 2 HHEX HLX LBX1 LBX2 MSX 1 2 NANOG NKX 2-1 2-2 2-3 2-5 2-9 3-1 3-2 HMX1 HMX2 HMX3 6-1 6-2

    HNF1A

    HNF1A

    HNF1A

  • Autoimmune regulator

    • Immune system protein

    BARHL1 BARHL2 BARX1 BARX2 BSX DBX 1 2 DLX 1 2 3 4 5 6 EMX 1 2 EN 1 2 HHEX HLX LBX1 LBX2 MSX 1 2 NANOG NKX 2-1 2-2 2-3 2-5 2-9 3-1 3-2 HMX1 HMX2 HMX3 6-1 6-2

    Autoimmune regulator

    Autoimmune regulator

    Autoimmune_regulator

  • RUNX2

    • Protein-coding gene in humans

    BARHL1 BARHL2 BARX1 BARX2 BSX DBX 1 2 DLX 1 2 3 4 5 6 EMX 1 2 EN 1 2 HHEX HLX LBX1 LBX2 MSX 1 2 NANOG NKX 2-1 2-2 2-3 2-5 2-9 3-1 3-2 HMX1 HMX2 HMX3 6-1 6-2

    RUNX2

    RUNX2

    RUNX2

  • NFKB1

    • Protein-coding gene in humans

    BARHL1 BARHL2 BARX1 BARX2 BSX DBX 1 2 DLX 1 2 3 4 5 6 EMX 1 2 EN 1 2 HHEX HLX LBX1 LBX2 MSX 1 2 NANOG NKX 2-1 2-2 2-3 2-5 2-9 3-1 3-2 HMX1 HMX2 HMX3 6-1 6-2

    NFKB1

    NFKB1

    NFKB1

  • Wilms tumor protein

    • Transcription factor gene involved in the urogenital system

    BARHL1 BARHL2 BARX1 BARX2 BSX DBX 1 2 DLX 1 2 3 4 5 6 EMX 1 2 EN 1 2 HHEX HLX LBX1 LBX2 MSX 1 2 NANOG NKX 2-1 2-2 2-3 2-5 2-9 3-1 3-2 HMX1 HMX2 HMX3 6-1 6-2

    Wilms tumor protein

    Wilms tumor protein

    Wilms_tumor_protein

  • PDX1

    • Protein involved in the pancreas and duodenum differentiation

    BARHL1 BARHL2 BARX1 BARX2 BSX DBX 1 2 DLX 1 2 3 4 5 6 EMX 1 2 EN 1 2 HHEX HLX LBX1 LBX2 MSX 1 2 NANOG NKX 2-1 2-2 2-3 2-5 2-9 3-1 3-2 HMX1 HMX2 HMX3 6-1 6-2

    PDX1

    PDX1

    PDX1

  • STAT6

    • Protein and coding gene in humans

    BARHL1 BARHL2 BARX1 BARX2 BSX DBX 1 2 DLX 1 2 3 4 5 6 EMX 1 2 EN 1 2 HHEX HLX LBX1 LBX2 MSX 1 2 NANOG NKX 2-1 2-2 2-3 2-5 2-9 3-1 3-2 HMX1 HMX2 HMX3 6-1 6-2

    STAT6

    STAT6

    STAT6

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