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See searches and references containing INTERMEMBRANE SPACE!INTERMEMBRANE SPACE
Part of a cell
An intermembrane space refers to the region of space which occurs between two or more adjacent plasma membranes within a given cellular organelle. Most
Intermembrane_space
Organelle in eukaryotic cells responsible for respiration
functions. These compartments or regions include the outer membrane, intermembrane space, inner membrane, cristae, and matrix. In addition to supplying cellular
Mitochondria
Plant organelle that conducts photosynthesis
thylakoids and intermembrane space. The protein-rich, alkaline, aqueous fluid within the inner chloroplast membrane and outside of the thylakoid space is called
Chloroplast
Cell structure
mitochondrial membrane which separates the mitochondrial matrix from the intermembrane space. The structure of the inner mitochondrial membrane is extensively
Inner_mitochondrial_membrane
Space within the inner membrane of the mitochondrion
reduced in oxidative phosphorylation to produce ATP. The cytosolic, intermembrane space, compartment has a higher aqueous:protein content of around 3.8 μL/mg
Mitochondrial_matrix
Biological mechanism for routing proteins
membrane complex TOM20/22 to the intermembrane space. In which they will interact with TIM9/10 intermembrane-space protein complex that transfers them
Protein_targeting
Energy-producing metabolic pathway
is used by the electron transport chain to pump protons into the intermembrane space, generating the electrochemical gradient over the inner mitochondrial
Electron_transport_chain
Index of articles associated with the same name
Epidural space Extraperitoneal space Fascial spaces of the head and neck Infratemporal space Intercostal space Intermembrane space Interstitial spaces Mental
Anatomic_space
Protein-coding gene in the species Homo sapiens
from the mitochondrial matrix, across the inner membrane, into the intermembrane space. IMMP2L processes the nuclear encoded protein DIABLO. The gene IMMP2L
IMMP2L
Series of reactions in cellular respiration
ubiquinol to ubiquinone, and the transfer of four protons into the intermembrane space, per two-cycle process. Ubiquinol (QH2) binds to the Qo site of complex
Q_cycle
Metabolic pathway
molecules. In the mitochondria, electrons are transferred within the intermembrane space by the water-soluble electron transfer protein cytochrome c. This
Oxidative_phosphorylation
Energy-carrying molecule in living cells
to aspartate for transport back across the membrane and into the intermembrane space. In oxidative phosphorylation, the passage of electrons from NADH
Adenosine_triphosphate
Class of enzymes
concomitant pumping of 4 protons from the mitochondrial matrix to the intermembrane space: QH2 + 2 cytochrome c (FeIII) + 2 H+ in → Q + 2 cytochrome c (FeII)
Coenzyme Q – cytochrome c reductase
Coenzyme_Q_–_cytochrome_c_reductase
Electrochemical principle that enables cellular respiration
redox transfer step is used to pump protons from the matrix into the intermembrane space, storing energy in the form of a transmembrane electrochemical gradient
Chemiosmosis
Compound active in mitochondria
CPT1). The fatty acylcarnitine ester formed then diffuses across the intermembrane space and enters the matrix by facilitated diffusion through carnitine-acylcarnitine
Carnitine
Biological process to convert light into chemical energy
phospholipid inner membrane, a phospholipid outer membrane, and an intermembrane space. Enclosed by the membrane is an aqueous fluid called the stroma.
Photosynthesis
Protein-coding gene in the species Homo sapiens
are organized in heterooligomeric complexes in the mitochondrial intermembrane space. These proteins mediate the import and insertion of hydrophobic membrane
TIMM10
Fold in the inner membrane of a mitochondrion
stored as NADH and FADH2. The energy is used to pump H+ ions into the intermembrane space, establishing an electrochemical gradient, while electrons are ultimately
Crista
Mammalian protein found in Homo sapiens
encoded in humans by the AK2 gene. The AK2 protein is found in the intermembrane space of the mitochondrion. Adenylate kinases are involved in regulating
AK2
Reactive oxygen species produced by mitochondria
mitochondrial matrix and superoxide dismutase 1 (SOD1) in mitochondrial intermembrane space. Collectively, both superoxide and hydrogen peroxide generated in
Mitochondrial_ROS
Enzyme decomposing hydrogen peroxide
intracellular membrane-bounded organelle focal adhesion mitochondrial intermembrane space peroxisomal membrane peroxisome plasma membrane peroxisomal matrix
Catalase
Protein-coding gene in humans
respiratory chain that catalyzes the transfer of electrons from intermembrane space cytochrome c to molecular oxygen in the matrix and as a consequence
COA6
Protein-coding gene in humans
SOD1 that is targeted to the mitochondria must be inserted into the intermembrane space. There, it forms the disulfide bond, though not metalation, required
SOD1
Genus of carnivorous plants
decouple electron transport from proton pumping. By doing so, the intermembrane space could sequester protons and store them until the ATP is needed. Such
Utricularia
Biochemical system for transporting electrons produced during glycolysis
mitochondrial matrix and intermembrane space. Aspartate aminotransferase in the mitochondrial matrix and intermembrane space. Malate–α-ketoglutarate antiporter
Malate–aspartate_shuttle
matrix-facing leaflet becomes the outer surface of the SMP, and the intermembrane space-facing leaflet faces the lumen of the SMP. As a consequence, the
Submitochondrial_particle
Aerobic respiration enzyme
Rudel T (February 2014). "C1orf163/RESA1 is a novel mitochondrial intermembrane space protein connected to respiratory chain assembly". Journal of Molecular
Cytochrome_c_oxidase
envelope membranes are separated by a gap of 10–20 nm, called the intermembrane space. Within the envelope membranes, in the region called the stroma,
Chloroplast_membrane
Membrane enclosed compartments in chloroplasts and cyanobacteria
lipid bodies. The relatively large distance between the thylakoids provides space for the external light-harvesting antennae, the phycobilisomes. This macrostructure
Thylakoid
proteins that assist in transport of hydrophobic precursors across the intermembrane space in mammalian cells. Both Tim9 and Tim10 form a hexamer, the Tim9-Tim10
Tim9-Tim10_complex
Protein found in humans
c is widely believed to be localised solely in the mitochondrial intermembrane space under normal physiological conditions. The release of cytochrome c
Cytochrome_c
Enzyme found in humans
subsequent movement of the acyl carnitine from the cytosol into the intermembrane space of mitochondria. Three isoforms of CPT1 are currently known: CPT1A
Carnitine palmitoyltransferase I
Carnitine_palmitoyltransferase_I
Protein-coding gene in the species Homo sapiens
are organized in heterooligomeric complexes in the mitochondrial intermembrane space. These proteins mediate the import and insertion of hydrophobic membrane
TIMM9
Protein-coding gene in the species Homo sapiens
are organized in heterooligomeric complexes in the mitochondrial intermembrane space. These proteins mediate the import and insertion of hydrophobic membrane
TIMM10B
Class of enzymes
Mitochondrial creatine kinase (CKm) is present in the mitochondrial intermembrane space, where it regenerates phosphocreatine (PCr) from mitochondrially
Creatine_kinase
Protein-coding gene in the species Homo sapiens
normally a mitochondrial protein localized to the mitochondrial intermembrane space, but it enters the cytosol when cells undergo apoptosis. Through
Diablo_homolog
Protein-coding gene in the species Homo sapiens
kinase binding RNA binding Cellular component membrane mitochondrial intermembrane space lipid droplet nucleoplasm mitochondrial matrix mitochondrion mitochondrial
TRAP1
In plants, the colorless fluid surrounding the grana within the chloroplast
Chloroplast envelope 2.1 Outer membrane 2.2 Intermembrane space 2.3 Inner membrane 3 Thylakoid 3.1 Thylakoid space (lumen) 3.2 Thylakoid membrane 4 Stromal
Stroma_(fluid)
Protein family
the movement of proteins across the outer membrane and into the intermembrane space of the mitochondrion. A major proportion of the proteins required
Translocase of the outer membrane
Translocase_of_the_outer_membrane
Protein-coding gene in the species Homo sapiens
protein import into the mitochondrial matrix with export to the intermembrane space" (PDF). Cell. 68 (6): 1163–75. doi:10.1016/0092-8674(92)90086-R.
GroEL
protein binding Cellular component mitochondrial matrix mitochondrial intermembrane space mitochondrion Biological process sulfur compound metabolic process
Sulfite_oxidase
Peptide hormone
mitochondrial enzyme important for bringing fatty acids into the intermembrane space of the mitochondria for β-oxidation. Glucagon decreases malonyl-CoA
Glucagon
Process by which cells build mitochondrial mass
mitochondria, which include the outer membrane, inner membrane, intermembrane space, and matrix. All proteins will enter the mitochondria by a translocase
Mitochondrial_biogenesis
Use of arsenic trioxide as a medication
(apoptosis-inducing factor), Smac/DIABLO protein, and endonucleases from the intermembrane space of mitochondria into the cytosol. In the cytoplasm, a protein complex
Arsenic_trioxide_(medication)
Chemical compound
acyl-CoA synthetase, 2: translocase, A: outer mitochondrial membrane, B: Intermembrane space, C: inner mitochondrial membrane, D: mitochondrial matrix)
Meldonium
Protein-coding gene in the species Homo sapiens
localizes to the inner mitochondrial membrane and is exposed to the intermembrane space. Mutations in this gene are associated with mitochondrial complex
PET100
Central nervous system disease
by regulating the release of cytochrome c from the mitochondrial intermembrane space. Reactive oxygen species (ROS) are normal byproducts of mitochondrial
Neurodegenerative_disease
Enzyme
electron transport chain, drives the (H+) proton cations from the intermembrane space through the membrane via the FO region of ATP synthase. A portion
ATP_synthase
Biochemical shuttle reaction
membrane. The acyl-carnitine diffuses through the membrane into the intermembrane space for step two. Three types of this enzyme exist in humans: CPT IA
Carnitine_shuttle
Protein-coding gene in the species Homo sapiens
deglutarylase activity Cellular component cytoplasm mitochondrial intermembrane space mitochondrion nucleus cytosol mitochondrial matrix mitochondrial
Sirtuin_5
Mammalian protein found in Homo sapiens
envelope membrane transcription regulator complex mitochondrial intermembrane space sarcoplasmic reticulum mitochondrial outer membrane endoplasmic reticulum
HAX1
Protein found in humans
extracellular space supramolecular fiber soma mitochondrial outer membrane mitochondrial inner membrane mitochondrial intermembrane space mitochondrial
Alpha-synuclein
Series of chemical reactions
from the inner membrane to the intermembrane space. There is a net movement of the citrate from the intermembrane space to the cytosol across the outer
Citrate–malate_shuttle
Protein-coding gene in the species Homo sapiens
binding Cellular component mitochondrial inner membrane mitochondrial intermembrane space mitochondrion respiratory chain complex IV Biological process substantia
COX6B1
Protein-coding gene in the species Homo sapiens
reticulum membrane mitochondrial membranes membrane mitochondrial intermembrane space smooth endoplasmic reticulum membrane endoplasmic reticulum mitochondrion
HSD3B2
Protein-coding gene in the species Homo sapiens
into the trabecular meshwork of the mitochondria. In the extracellular space, it appears in the trabecular meshwork cells through an unconventional mechanism
Myocilin
Intracellular energy shuttle in muscles
opposite direction of phosphocreatine, back towards the mitochondrial intermembrane space where it can be rephosphorylated by creatine phosphokinase. At the
Creatine_phosphate_shuttle
Mammalian protein found in Homo sapiens
oxidoreductase activity Cellular component membrane mitochondrial intermembrane space mitochondrion mitochondrial inner membrane cytosol cytoplasm Biological
Coproporphyrinogen III oxidase
Coproporphyrinogen_III_oxidase
Protein found in humans
a potent protein disaggregase that chaperones the mitochondrial intermembrane space. Mutations in the CLPB gene could cause autosomal recessive metabolic
CLPB
Protein-coding gene in the species Homo sapiens
encoded protein and the TIMM8a protein form a 70 kDa complex in the intermembrane space. This gene is in a head-to-tail orientation with the gene for lamin
TIMM13
Enzyme
activity Cellular component mitochondrial inner membrane mitochondrial intermembrane space intrinsic component of mitochondrial inner membrane membrane mitochondrion
Protoporphyrinogen_oxidase
Mammalian protein found in Homo sapiens
ligase binding Cellular component cytoplasm cytosol mitochondrial intermembrane space nucleus Biological process cellular response to tumor cell response
TXNIP
Highly reactive molecules formed from diatomic oxygen (O2)
chain-dependent generation of superoxide anion and its release into the intermembrane space". The Biochemical Journal. 353 (Pt 2): 411–416. doi:10.1042/0264-6021:3530411
Reactive_oxygen_species
Protein-coding gene in the species Homo sapiens
attach to the IMM, and short isoforms (S-OPA1), which localize to the intermembrane space (IMS) near the outer mitochondrial membrane (OMM). S-OPA1 is formed
Dynamin-like_120_kDa_protein
Protein-coding gene in the species Homo sapiens
mitochondrial respiratory chain complex I membrane mitochondrial intermembrane space myelin sheath mitochondrial inner membrane plasma membrane respiratory
NDUFS1
Family of waxy lipid molecules
mitochondrial outer membrane. This leads to the egress of proteins from the intermembrane space. In the metabolic disease combined malonic and methylmalonic aciduria
Ceramide
which is approximately 0.9 pH units higher than that of inside intermembrane space. Since oxidative phosphorylation must occur inside the mitochondria
Intracellular_pH
Protein-coding gene in the species Homo sapiens
mitochondrial inner membrane integral component of membrane mitochondrial intermembrane space TIM23 mitochondrial import inner membrane translocase complex mitochondrion
TIMM23
Form of programmed cell death
cells are stressed and depends on the release of proteins from the intermembrane space of mitochondria. The extrinsic pathway is activated by extracellular
Apoptosis
Structural element of proteins
lumen of the RER (rough endoplasmic reticulum) and the mitochondrial intermembrane space but not in the cytosol. This is due to the more oxidizing environment
Disulfide_(biochemistry)
Peptide hormone
mitochondrial enzyme necessary for the translocation of fatty acids into the intermembrane space of the mitochondria for fatty acid metabolism. Insulin also influences
Insulin
Mitochondrial protein
pumping of protons from the mitochondrial matrix to the mitochondrial intermembrane space. The energy lost in dissipating the proton gradient via UCPs is not
Uncoupling_protein
Chemical compound used as a herbicide
inner mitochondrial membrane (IMM). Protons are taken up from the intermembrane space and after transport through the IMM, they are released again in the
Dinoseb
Protein-coding gene found in humans
binding Cellular component cytoplasm cytosol membrane mitochondrial intermembrane space mitochondrion neuron projection nucleus mitochondrial respiratory
DJ-1
Class of transport proteins
the matrix and the cytoplasmic sides of the membrane. ADP in the intermembrane space, coming from the cytoplasm, binds the translocase and induces its
Adenine nucleotide translocator
Adenine_nucleotide_translocator
Protein-coding gene in humans
electron transfer activity Cellular component cytoplasm mitochondrial intermembrane space nucleolus nucleus nucleoplasm mitochondrion Biological process methylation
CIAPIN1
cartilaginous (and hepatic) mitochondria, by diffusing from the intermembrane space as a proton carrier back into the mitochondrial matrix, where it
Mechanism of action of aspirin
Mechanism_of_action_of_aspirin
Protein family
maturation of cytochromes c occurs in the periplasm of prokaryotes, the intermembrane space of mitochondria or the stroma of chloroplasts. Several biochemical
Cytochrome_c_family
Protein-coding gene in humans
disassembly in apoptotic cells that is found in the mitochondrial intermembrane space in healthy cells. Induction of apoptosis results in the cleavage
AIFM1
Chemical compound
proton pool and minimizing the changes in pH in the mitochondrial intermembrane space. This function is due to CL's unique structure. As stated above,
Cardiolipin
Protein-coding gene in the species Homo sapiens
lipid binding Cellular component cytoplasm membrane mitochondrial intermembrane space plasma membrane T cell receptor complex mitochondrion immunological
STOML2
Metabolic reaction
ATP synthase acting as a pore, allowing H+ from the mitochondrial intermembrane space to move down its electrochemical gradient into the matrix and coupling
Substrate-level phosphorylation
Substrate-level_phosphorylation
Protein complex involved in the cellular apoptotic process
mitochondrial Ca2+ levels and oxidative stress, leading to the release of intermembrane space proteins. The mPTP has several components, including the adenine
Apoptosome
Protein-coding gene in the species Homo sapiens
membrane-bounded organelle membrane Golgi cisterna mitochondrial intermembrane space plasma membrane Golgi cisterna membrane trans-Golgi network mitochondrion
GOLPH3
Protein family
translated in the cytosol and recruited to the mitochondrial membrane and intermembrane space by its N-terminal mitochondrial localization signal (MLS). Inside
Apoptosis-inducing_factor
Protein-coding gene in the species Homo sapiens
binding Cellular component cytoplasm cytosol membrane mitochondrial intermembrane space mitochondrion perinuclear region of cytoplasm cytoskeleton nucleus
PINK1
DNA located in cellular organelles called chloroplasts
time, but the TIC complex can also retrieve preproteins lost in the intermembrane space. Like the TOC translocon, the TIC translocon has a large core complex
Plastid_DNA
Protein-coding gene in the species Homo sapiens
membrane insertion complex mitochondrial inner membrane mitochondrial intermembrane space Biological process glycerolipid metabolic process ceramide biosynthetic
Acylglycerol kinase, mitochondrial
Acylglycerol_kinase,_mitochondrial
Class of enzymes
the structure of enzymes responsible for oxidative folding in the intermembrane space of the mitochondria; an example of this is mitochondrial IMS import
Protein_disulfide-isomerase
Protein-coding gene in humans
response to stress, the protein translocates from the mitochondrial intermembrane space to the nucleus where it binds to a highly conserved 13 nucleotide
CHCHD2
Protein-coding gene in humans
precursors from aggregation and guide them through the mitochondrial intermembrane space. The TIMM8-TIMM13 complex mediates the import of proteins such as
TIMM8A
Protein encoded by the CYC1 gene
chain. It is formed in the cytosol and targeted to the mitochondrial intermembrane space. Cytochrome c1 belongs to the cytochrome c family of proteins. Cytochrome
Cytochrome_C1
Protein-coding gene in humans
Cellular component cytoplasm mitochondrial matrix mitochondrial intermembrane space nucleolus nucleus focal adhesion mitochondrion Biological process
REXO2
System of signaling molecules within a cell
membrane-associated and diffuse from the plasma membrane into the intermembrane space where they can reach and regulate membrane-associated effector proteins
Second_messenger_system
Protein-coding gene in the species Homo sapiens
complex mitochondrial intermembrane space mitochondrial matrix mitochondrion extracellular exosome axon cytoplasm extracellular space lysosome lysosomal
BLOC1S1
Protein-coding gene in the species Homo sapiens
component membrane BRISC complex microtubule cytoskeleton mitochondrial intermembrane space extracellular exosome mitochondrial inner membrane cytoplasm mitochondrion
Serine hydroxymethyltransferase 2
Serine_hydroxymethyltransferase_2
Protein-coding gene in the species Homo sapiens
membrane mitochondrion intracellular anatomical structure mitochondrial intermembrane space Biological process nucleobase-containing small molecule interconversion
NME4
Gradient of electrochemical potential, usually for an ion that can move across a membrane
membrane. Complexes I, III, and IV pump protons from the matrix to the intermembrane space (IMS); for every electron pair entering the chain, ten protons translocate
Electrochemical_gradient
Protein-coding gene in the species Homo sapiens
Molecular function protein binding Cellular component mitochondrial intermembrane space mitochondrial crista mitochondrion Biological process proton transmembrane
COX6B2
Protein-coding gene in the species Homo sapiens
component of membrane membrane mitochondrial membranes mitochondrial intermembrane space smooth endoplasmic reticulum membrane endoplasmic reticulum mitochondrion
HSD3B1
INTERMEMBRANE SPACE
INTERMEMBRANE SPACE
Girl/Female
Indian, Telugu
Goddess of Space
Boy/Male
Muslim
Open space, Battle field
Boy/Male
Hindu
Space
Boy/Male
Indian
Open space, Battle field
Girl/Female
Biblical
Spaces, places.
Boy/Male
Hindu
Space
Boy/Male
Hindu
Limitless space Avatar incarnation
Girl/Female
Maori
Open spaces.
Surname or Lastname
English
English : habitational name from either of two places in Cheshire. It is possible that the name originally denoted a building where village assemblies were held, named in Old English as ‘meeting-house’, from (ge)mÅt ‘meeting’ + ærn ‘house’, ‘hall’. Other possibilities are that the name derives from Old English (ge)mÅt-rÅ«m ‘meeting space’, or (ge)mÅt-treum ‘assembly trees’.
Girl/Female
Tamil
Antariksha | அஂதரிகà¯à®·
Space, Sky
Antariksha | அஂதரிகà¯à®·
Girl/Female
Gujarati, Hindu, Indian
Star in Space
Girl/Female
Indian, Telugu
Space
Boy/Male
Arabic, Muslim, Pashtun
Battle Field; Open Space
Boy/Male
Hindu
Space
Boy/Male
Tamil
Limitless space Avatar incarnation
Surname or Lastname
English or Scottish
English or Scottish : unexplained.
Boy/Male
Tamil
Antrix | அஂதà¯à®°à¯€à®•à¯à®·
Space
Antrix | அஂதà¯à®°à¯€à®•à¯à®·
Boy/Male
Biblical
Breadth, space, extent.
Girl/Female
Indian, Japanese, Tamil
Space; Star
Surname or Lastname
English
English : occupational name for a wattler, Middle English watelere, i.e. someone who made the panels of interwoven twigs that were used to fill the spaces between the structural timbers of a timber frame building. See also Dauber.
INTERMEMBRANE SPACE
INTERMEMBRANE SPACE
INTERMEMBRANE SPACE
INTERMEMBRANE SPACE
INTERMEMBRANE SPACE
INTERMEMBRANE SPACE
INTERMEMBRANE SPACE