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Protein-coding gene in humans
Homeobox protein Hox-A9 is a protein that in humans is encoded by the HOXA9 gene. In vertebrates, the genes encoding the class of transcription factors
HOXA9
Non-coding RNA in the species Homo sapiens
HOXA10-HOXA9 readthrough is a gene that is unlikely to produce a protein product. This locus represents naturally occurring read-through transcription
HOXA10-HOXA9
Protein complex
KMT2A target genes, thus promoting sustained transcription of genes such as HOXA9 that drive leukemia. Components of the super elongation complex include
Super_elongation_complex
Topics referred to by the same term
in higher vertebrates, or one of the following genes associated with it: HOXA9 HOXA11 HOXA11-AS1 (gene) HOXA13 HOXA, the Hazaribagh Old Xaverians Association
Hoxa
Group of genes
Genes HOXA@ chromosome 7 HOXA1, HOXA2, HOXA3, HOXA4, HOXA5, HOXA6, HOXA7, HOXA9, HOXA10, HOXA11, HOXA13 HOXB@ chromosome 17 HOXB1, HOXB2, HOXB3, HOXB4,
Hox_gene
Paired ducts in the mammalian embryo in the primitive urogenital structures
development of the uterus and cervix, in the MDM. Two additional Hox genes, HoxA9 and HoxA13, specify the development of the Fallopian tube and the upper
Paramesonephric_duct
Protein-coding gene in the species Homo sapiens
Kedinger M, Simon-Assmann P (December 2002). "[Increased expression of HOXA9 gene in Hirschsprung disease]". Gastroenterologie Clinique et Biologique
HOXA4
Protein-coding gene in humans
degradation is HOXA9, which is essential for haematopoietic stem cell maintenance and has been implicated in a subset of myeloid leukemias. The HOXA9 degron lies
CUL4A
Protein-coding gene in the species Homo sapiens
"Single-translocation and double-chimeric transcripts: detection of NUP98-HOXA9 in myeloid leukemias with HOXA11 or HOXA13 breaks of the chromosomal translocation
HOXA13
Protein-coding gene in the species Homo sapiens
Bellocq JP, Kedinger M, Simon-Assmann P (2003). "[Increased expression of HOXA9 gene in Hirschsprung disease]". Gastroenterol. Clin. Biol. 26 (12): 1110–7
HOXD9
Protein found in humans
histocompatibility complex (MHC) on chromosome 6. PBX2 has been shown to interact with HOXA9. ENSG00000237344, ENSG00000236353, ENSG00000232005, ENSG00000225987, ENSG00000206315
PBX2
Protein-coding gene in humans
homeodomain-containing proteins. MEIS1 has been shown to interact with PBX1 and HOXA9. GRCh38: Ensembl release 89: ENSG00000143995 – Ensembl, May 2017 GRCm38:
MEIS1
ENSG00000122592 Homeodomain Known motif – High-throughput in vitro [381] TAATKRV HOXA9 ENSG00000078399 Homeodomain Known motif – High-throughput in vitro [382]
List of human transcription factors
List_of_human_transcription_factors
Protein-coding gene in the species Homo sapiens
nucleoporin-specific FG repeats that activate transcription and mediate NUP98-HOXA9 oncogenicity". Mol. Cell. Biol. 19 (1): 764–76. doi:10.1128/mcb.19.1.764
NUP98
Medical condition
additional ones), Holmes et al. did not find abnormalities in the HOXD10, HOXA9, and HOXC9 genes. They concluded this was part of a brand new (novel) autosomal
Absent tibia-polydactyly-arachnoid cyst syndrome
Absent_tibia-polydactyly-arachnoid_cyst_syndrome
Protein-coding gene in the species Homo sapiens
methylation profiling of ovarian carcinomas and their in vitro models identifies HOXA9, HOXB5, SCGB3A1, and CRABP1 as novel targets". Molecular Cancer. 6 45. doi:10
CRABP1
Human chromosome
transcript 1 protein HOXA@: encoding protein Homeobox a cluster HOXA10-HOXA9: readthrough gene unlikely to produce a protein product HPC4: Prostate cancer
Chromosome_7
Protein found in humans
PMC 358760. PMID 7910944. Shen WF, Rozenfeld S, Kwong A, et al. (1999). "HOXA9 Forms Triple Complexes with PBX2 and MEIS1 in Myeloid Cells". Mol. Cell
PBX3
DNA pattern affecting anatomy development
HOX1) - HOXA@ chromosome 7 HOXA1, HOXA2, HOXA3, HOXA4, HOXA5, HOXA6, HOXA7, HOXA9, HOXA10, HOXA11, HOXA13 HOXB - HOXB@ chromosome 17 HOXB1, HOXB2, HOXB3,
Homeobox
Protein found in humans
Rozenfeld S, Kwong A, Köm ves LG, Lawrence HJ, Largman C (April 1999). "HOXA9 forms triple complexes with PBX2 and MEIS1 in myeloid cells". Molecular
PBX1
Protein-coding gene in the species Homo sapiens
(2004). "A conserved non-homeodomain Hoxa9 isoform interacting with CBP is co-expressed with the 'typical' Hoxa9 protein during embryogenesis". Gene Expr
MEIS2
Protein-coding gene in the species Homo sapiens
Sauvageau G, Nakamura T (2005). "Identification of cooperative genes for NUP98-HOXA9 in myeloid leukemogenesis using a mouse model". Blood. 105 (2): 784–793
DNAL4
Protein-coding gene in the species Homo sapiens
activity. This interaction is best characterized in the co-regulation of HOXA9 gene by SALL4 and MLL in leukemic cells. In mouse ESCs, Sall4 was found
SALL4
Protein-coding gene in the species Homo sapiens
Hirokawa K, Nakamura T (Jul 2001). "Inhibition of myeloid differentiation by Hoxa9, Hoxb8, and Meis homeobox genes". Experimental Hematology. 29 (7): 856–63
HOXB8
involving this gene often lead to leukemia. MLL's target genes include HOXC8, HOXA9, CDKN1B, and C-MYC. MLL also has two binding domains: a Cyp33 RNA-recognition
Proline isomerization in epigenetics
Proline_isomerization_in_epigenetics
RNA family
inhibiting the cell cycle from progressing from G0/G1into S phase. HOXA9, mir-126 modulates HOXA9 expression in haematopoietic cells. HOX genes are important
Mir-126
Gene regulation in autoimmune diseases
at the gene for HOXA9 transcription factor and DNA hypermethylation is observed at the FOXP3 immune response gene promoter region. HOXA9 codes for a protein
Epigenetics of autoimmune disorders
Epigenetics_of_autoimmune_disorders
Protein-coding gene in the species Homo sapiens
homeodomain containing proteins, including HoxA9, Hex/PRH, Hox 11, Bicoid, Emx-2 and Engrailed 2. While HoxA9 promotes mRNA export and translation activities
EIF4E
Protein-coding gene in the species Homo sapiens
fully characterized. TRIP6 has been shown to interact with LPAR2, BCAR1 and HOXA9. GRCh38: Ensembl release 89: ENSG00000087077 – Ensembl, May 2017 GRCm38:
TRIP6
Protein-coding gene in humans
understood. It is thought that ID4 plays a role in the transcription of HOXA9 and CDKN1A which are known to be associated with endometriosis. A genome
ID4
American medical doctor and hematologist
of transcription factors that influence stem cell fate decisions (HOXB4, HOXA9, c-Myb, HIF1A) and has unraveled the pathobiology of several congenital
Kenneth_Kaushansky
HGNC:5106; P20719 7198 HOXA6 HGNC:5107; P31267 7199 HOXA7 HGNC:5108; P31268 7200 HOXA9 HGNC:5109; P31269 7201 HOXA10 HGNC:5100; P31260 7202 HOXA11 HGNC:5101; P31270
List of human protein-coding genes 4
List_of_human_protein-coding_genes_4
1,132-amino acid
molecular mechanism(s) for this is unknown. Some HOXA genes, particularly HOXA9, are upregulated[broken anchor] in these NUTM1 fusion gene-associated ALL
Nuclear protein in testis gene
Nuclear_protein_in_testis_gene
Protein-coding gene in the species Homo sapiens
identified as targets of EZH2-mediated transcriptional repression include HOXA9, HOXC8, MYT1, CDKN2A and retinoic acid target genes. In cancer, EZH2 may
EZH2
Protein-coding gene in the species Homo sapiens
"Single-translocation and double-chimeric transcripts: detection of NUP98-HOXA9 in myeloid leukemias with HOXA11 or HOXA13 breaks of the chromosomal translocation
HOXA11
Non-coding RNA in the species Homo sapiens
colonies. Additionally, Hu et al. demonstrated that the homeobox protein, HOXA9, regulated MIR155HG expression in myeloid cells and that this miRNA played
MiR-155
Protein-coding gene in the species Homo sapiens
progenitor gene expression program centered on HOXA cluster genes, particularly HOXA9 and MEIS1 via its interaction with the BAF complex The translocation of
MN1_(gene)
Protein-coding gene in the species Homo sapiens
methylation profiling of ovarian carcinomas and their in vitro models identifies HOXA9, HOXB5, SCGB3A1, and CRABP1 as novel targets". Molecular Cancer. 6: 45.
SCGB3A1
Protein-coding gene in humans
of hematopoietic self-renewal through epigenetic repression of Hoxa7 and Hoxa9". Leukemia. 31 (3): 712–719. doi:10.1038/leu.2016.240. PMC 5332284. PMID 27554164
RAD21
Protein-coding gene in the species Homo sapiens
15 months. Research has found when BAALC is combined with the oncogene Hoxa9, BAALC blocks myeloid differentiation. This blocking induces leukemogenesis
BAALC
HOXA9
HOXA9
HOXA9
HOXA9
HOXA9
HOXA9
HOXA9
HOXA9
HOXA9