Search references for RAD21. Phrases containing RAD21
See searches and references containing RAD21!RAD21
Protein-coding gene in humans
Double-strand-break repair protein rad21 homolog is a protein that in humans is encoded by the RAD21 gene. RAD21 (also known as Mcd1, Scc1, KIAA0078,
RAD21
Protein-coding gene in the species Homo sapiens
homologous recombination and DNA looping. Cohesin is formed of SMC3, SMC1, RAD21 and either SA1 or SA2. Cohesin has a ring-like arrangement and it is thought
WAPAL
Protein-coding gene in humans
homologous recombination and DNA looping. Cohesin is formed of SMC3, SMC1, RAD21 and either SA1 or SA2. In humans, SMC3 is present in all cohesin complexes
SMC3
Medical condition
mutation/deletion in the RAD21 gene. A 2019 study suggest that beyond its known role in cell division and chromosome organization, RAD21 may also contribute
Sclerocornea
Medical condition
mutated. Since then, additional genes have been found (SMC1A, SMC3 and HDAC8, RAD21) that cause CdLS when changed. In July 2012, the fourth "CdLS gene"—HDAC8—was
Cornelia_de_Lange_syndrome
Protein-coding gene in humans
recombination and DNA looping. In somatic cells, cohesin is formed of SMC1A, SMC3, RAD21 and either SA1 or SA2 whereas in meiosis, cohesin is formed of SMC3, SMC1B
SMC1A
Protein complex that regulates the separation of sister chromatids during cell division
1997. Cohesin is a multi-subunit protein complex, made up of SMC1, SMC3, RAD21 and SCC3 (SA1 or SA2). SMC1 and SMC3 are members of the Structural Maintenance
Cohesin
Medical condition
HLCS, RUNX1, MIR125B2 (which is the gene for microRNA MiR125B2CTCF, STAG2, RAD21, SMC3, SMC1A, NIPBL, SUZ12, PRC2, JAK1, JAK2, JAK3, MPL, KRAS, NRAS, and
Transient myeloproliferative disease
Transient_myeloproliferative_disease
Protein-coding gene in humans
recombination and DNA looping. In somatic cells cohesin is formed of SMC3, SMC1, RAD21 and either SA1 or SA2 whereas in meiosis, cohesin is formed of SMC3, SMC1B
STAG2
Protein-coding gene in the species Homo sapiens
recombination and DNA looping. In somatic cells cohesin is formed of SMC3, SMC1, RAD21 and either SA1 or SA2 whereas in meiosis, cohesin is formed of SMC3, SMC1B
STAG1
Protein-coding gene in the species Homo sapiens
recombination and DNA looping. The core cohesin complex is formed of SMC3, SMC1, RAD21 and either SA1 or SA2. PDS5 associates with WAPL to stimulate the release
PDS5B
Cytoplasmic biomolecular condensates of proteins and RNA occurring in cells under stress
1 RACK1 RACK1 Receptor For Activated C Kinase 1 RAD21 RAD21 Double-strand-break repair protein rad21 homolog RAE1 RAE1 Ribonucleic Acid Export 1 RAN RAN
Stress_granule
recessive Cornelia de Lange syndrome (CDLS) HDAC8, SMC1A, NIPBL, SMA3, RAD21 1:10,000-30,000 Cowden syndrome PTEN 1:200,000 CPO deficiency (coproporphyria)
List_of_genetic_disorders
Mammalian protein found in Homo sapiens
complex. The second step involves cleavage of the cohesin subunit SCC1 (RAD21) by separase, which initiates the final separation of sister chromatids
Separase
SMC2 SMC5 SMC MukB JetC κ-SMC SMC1 SMC4 SMC4 SMC6 SMC MukB JetC kleisin RAD21 CAP-H CAP-H2 Nse4 ScpA MukF JetA HEAT-A NIPBL/Pds5 CAP-D2 CAP-D3 - - - -
SMC_protein
Protein-coding gene in the species Homo sapiens
S2CID 23783563. Porkka KP, Tammela TL, Vessella RL, Visakorpi T (2004). "RAD21 and KIAA0196 at 8q24 are amplified and overexpressed in prostate cancer"
WASHC5
Blood marrow cancer originating in megakaryoblast cells
HLCS, RUNX1, MIR125B2 (which is the gene for microRNA MiR125B2CTCF, STAG2, RAD21, SMC3, SMC1A, NIPBL, SUZ12, PRC2, JAK1, JAK2, JAK3, MPL, KRAS, NRAS, and
Acute megakaryoblastic leukemia
Acute_megakaryoblastic_leukemia
to as cohesinopathies. Genetic alterations in genes NIPBL, SMC1A, SMC3, RAD21 and HDAC8 are associated with Cornelia de Lange Syndrome. The proteins encoded
Establishment of sister chromatid cohesion
Establishment_of_sister_chromatid_cohesion
Protein-coding gene in humans
genes including: TP53, RUNX1, FLT3, ERG, DYRK1A, CHAF1B, HLCS, CTCF, STAG2, RAD21, SMC3, SMC1A, NIPBL, SUZ12, PRC2, JAK1, JAK2, JAK3, MPL, KRAS, NRAS, SH2B3
GATA1
Protein-coding gene in the species Homo sapiens
capable of. Additionally, in somatic cells SMC1B associates with SMC3 and RAD21 in a mitotic cohesin complex which had been thought to only include SMC1α
SMC1B
Definition of scientific term
Aggregates of chromomeres are known as chromonemata. Cohesive proteins SMC3 and hRAD21(plays a role in sister chromatid cohesion) are found within chromomeres
Chromomere
Protein-coding gene in the species Homo sapiens
Gomez L, Fernandez R, Martinez-A C, Barbero JL (June 2002). "STAG2 and Rad21 mammalian mitotic cohesins are implicated in meiosis". EMBO Reports. 3 (6):
STAG3
Protein family
Shugoshin protein is thought to act by protecting two proteins, named Rec8 and Rad21 at the centromeres from protein degradation by the enzyme separase. This
Shugoshin N terminal protein domain
Shugoshin_N_terminal_protein_domain
Protein-coding gene in the species Homo sapiens
ISWI chromatin remodeling protein. SMARCA5 has been shown to interact with RAD21, Histone deacetylase 2, POLE3, SATB1 and BAZ1A. GRCh38: Ensembl release
SMARCA5
Q6WBX8 13352 RAD17 HGNC:9807; O75943 13353 RAD18 HGNC:18278; Q9NS91 13354 RAD21 HGNC:9811; O60216 13355 RAD21L1 HGNC:16271; Q9H4I0 13356 RAD23A HGNC:9812;
List of human protein-coding genes 6
List_of_human_protein-coding_genes_6
Cell cycle checkpoint
form an heterodimer (Smc1p/Smc3p). Scc1p is the homolog in S.cerevisiae of Rad21, first identified as a protein involved in DNA repair in S. pombe. These
Spindle_checkpoint
Protein
Matsusaka T, Morrison C, Vagnarelli P, Hoshi O, Ushiki T, et al. (2001). "Scc1/Rad21/Mcd1 is required for sister chromatid cohesion and kinetochore function
Aurora_kinase_B
Long non-coding RNA transcribed from telomeres
chromatin organization factors CTCF (CCCTC-Binding Factor), Cohesin, and Rad21 - which are known to aid in the recruitment of RNAPII - have also been shown
Telomeric repeat–containing RNA
Telomeric_repeat–containing_RNA
RAD21
RAD21
RAD21
RAD21
RAD21
RAD21
RAD21
RAD21
RAD21