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Medication
Extended-release (or slow-release) formulations of morphine are those whose effect lasts substantially longer than bare morphine, availing for, e.g., one
Extended-release_morphine
Mechanism that delivers a drug with a delay after its administration
formulations of the same drug. For example, orally administered extended-release morphine can enable certain chronic pain patients to take only 1–2 tablets
Modified-release_dosage
Pain medication of the opiate family
(5 mg & 10 mg) of morphine sulfate extended-release 1 milliliter ampoule containing 10 mg of morphine Relative contraindications to morphine include: Respiratory
Morphine
Medication mainly used for depression and smoking cessation
Retrieved 5 May 2020. "Contrave Extended-Release – naltrexone hydrochloride and bupropion hydrochloride tablet, extended-release". DailyMed. 26 April 2019.
Bupropion
Withdrawal symptoms of opioids
instant-release morphine (shorter duration of action), withdrawal symptoms begin 8 to 24 hours after the last dose and persist for 4 to 10 days. For extended-release
Opioid_withdrawal
Gamma-aminobutyric acid analog
its oral bioavailability; when gabapentin was co-administered with oral morphine, the oral bioavailability of a 600 mg dose of gabapentin increased by 50%
Gabapentin
Medication
self-injury is believed to be done to release beta-endorphin, which binds to the same receptors as heroin and morphine. If the "rush" generated by self-injury
Naltrexone
Opioid medication used for pain relief
equivalent to approximately 10 mg morphine IV. Hydromorphone was patented in 1923. Hydromorphone is made from morphine. Hydromorphone is a therapeutic alternative
Hydromorphone
Alpha-adrenergic agonist
non-stimulant pharmacological treatment for ADHD and is USFDA-approved in its extended-release formulation as both a monotherapy and an adjunctive therapy to psychostimulants
Clonidine
Class of depressant drugs derived from barbituric acid
addicts. The pharmacological treatment of barbiturate withdrawal is an extended process often consisting of converting the patient to a long-acting benzodiazepine
Barbiturate
Class of CNS depressant drugs
persist into the next day and are, in general, not recommended. Since the release of nonbenzodiazepines, also known as z-drugs, in 1992 in response to safety
Benzodiazepine
Opioid analgesic and recreational drug
diluted with cutting agents. Black tar heroin is a variable admixture of morphine derivatives—predominantly 6-MAM (6-monoacetylmorphine), which is the result
Heroin
Pharmaceutical company in Cambridge, United Kingdom
abused its dominant position in the market for the supply of sustained release morphine tablets and capsules, contrary to competition law. Napp's subsequent
Napp_Pharmaceuticals
Class of drug
opioid receptors in the brain and other organs to produce a variety of morphine-like effects, including pain relief. The terms opioid and opiate are sometimes
Opioid
Medical condition
used medication interventions in reducing illicit opiate use. An extended-release morphine confers a possible reduction of opioid use and with fewer depressive
Opioid_use_disorder
Opioid analgesic
5 hours for morphine. The length of the half-life of methadone allows for the exhibition of respiratory depressant effects for an extended duration of
Methadone
Medication
excitotoxic neuronal death. Withdrawal from alcohol induces a surge in release of excitatory neurotransmitters like glutamate, which activates NMDARs
Acamprosate
Semi-synthetic opioid
reason dihydrocodeine, ethylmorphine, codeine, opium preparations, and morphine are used to stop diarrhoea and combat irritable bowel syndrome (IBS) in
Dihydrocodeine
Opioid used to treat pain and opioid use disorder
potent than morphine. When used as a transdermal patch, the potency of buprenorphine may be 100 to 115 times greater than that of morphine. Common adverse
Buprenorphine
Chemical stimulant produced by some plants
the central nervous system and peripheral tissues. This results in the release of neurotransmitters such as dopamine, acetylcholine, and norepinephrine
Nicotine
Medical condition
dosage. Changes in the expression of neuropeptides such as corticotropin-releasing hormone and neuropeptide Y may play a role in benzodiazepine dependence
Benzodiazepine_dependence
Need for a drug, whose discontinuation results in withdrawal symptoms
use, corticotropin-releasing factor (CRF) the hypothalamic–pituitary–adrenal axis (HPA axis) and other stress systems in the extended amygdala. This activation
Substance_dependence
Muscle relaxant medication
mono-and-polysynaptic reflexes by acting as an inhibitory ligand, inhibiting the release of excitatory neurotransmitters. Baclofen does not have significant affinity
Baclofen
Type of chewing gum that delivers nicotine to the body
throughout the day, and its reliance on chewing as the mechanism of nicotine release leads to more variable levels of nicotine in the blood than the patch.
Nicotine_gum
Chronic disease
nicotinic acetylcholine receptors in the brain, which subsequently causes the release of dopamine and other neurotransmitters, such as norepinephrine, acetylcholine
Nicotine_dependence
Chemical compound
compliance. Methods to improve compliance include subdermal implants, which release the drug continuously over a period of up to 12 weeks, and supervised administration
Disulfiram
Chemical compound
Methadone Dihydrocodeine Dihydroetorphine Hydromorphone (extended-release) Morphine (extended-release) Opioid antagonists (Naltrexone Nalmefene) Benzodiazepine
Cytisine
Investigational substance-related disorder drugs
Other opioids (opioid agonist therapy) (e.g., dihydrocodeinone, extended-release morphine) – μ-opioid receptor agonists – opioid use disorder Tianeptine
List of investigational substance-related disorder drugs
List_of_investigational_substance-related_disorder_drugs
Drug that inhibits the action of acetylcholine at nicotinic acetylcholine receptors
Methadone Dihydrocodeine Dihydroetorphine Hydromorphone (extended-release) Morphine (extended-release) Opioid antagonists (Naltrexone Nalmefene) Benzodiazepine
Nicotinic_antagonist
Opioid treatment
may increase access to treatment for opioid dependence". FDA.gov (Press release). US: Food and Drug Administration. Archived from the original on September
Buprenorphine/naloxone
CNS depressant medication
these cases solely included Phenibut. Phenibut may mutually potentiate and extend the duration of the effects of other CNS depressants, including anxiolytics
Phenibut
Vaccine in development for nicotine addiction
Methadone Dihydrocodeine Dihydroetorphine Hydromorphone (extended-release) Morphine (extended-release) Opioid antagonists (Naltrexone Nalmefene) Benzodiazepine
TA-NIC
Medical condition
Methadone Dihydrocodeine Dihydroetorphine Hydromorphone (extended-release) Morphine (extended-release) Opioid antagonists (Naltrexone Nalmefene) Benzodiazepine
Alcohol_dependence
Combination medication
regarding Embeda's reduced abuse potential. "Embeda- morphine sufate capsule, extended release". DailyMed. 22 January 2010. Retrieved 7 June 2023. "Medication
Morphine/naltrexone
Drug class
Cheng KI, Wong CS, Sun WZ (September 2023). "Multimodal Analgesia With Extended-Release Dinalbuphine Sebacate for Perioperative Management: Expert Opinion
Κ-Opioid_receptor_agonist
Opioid medication
as a second-line alternative to morphine by mouth for cancer pain. In children between 11 and 16, the extended-release formulation is FDA-approved for
Oxycodone
Supplement and medication used to treat sleep disorders
medication in the United States, with more than 3 million prescriptions. An extended-release pharmaceutical formulation of melatonin is approved under the brand
Melatonin as a medication and supplement
Melatonin_as_a_medication_and_supplement
Chemical compound
(suppression of urea formation), neutralizes alkalinity (ammonia) and continually releases small amounts of formic acid. Cyanamide, under the trade name Dormex, is
Cyanamide
Nicotinic receptor agonist
acetylcholine receptor partial agonist. When activated, this receptor leads to the release of dopamine in the nucleus accumbens, the brain's reward center, thereby
Varenicline
Drug that stimulates a response from the adrenergic receptors
action includes competitive and non-competitive reuptake inhibition and releasing agents. Examples include methylphenidate, atomoxetine, cocaine, and some
Adrenergic_agonist
Drug that causes an adverse reaction to alcohol
inhibit the metabolism of alcohol into acetaldehyde, thereby increasing and extending the effects of alcohol and reducing its toxicity. As such, they can be
Disulfiram-like_drug
Tranquilizer used in Russia for the treatment of alcohol withdrawal syndrom
Methadone Dihydrocodeine Dihydroetorphine Hydromorphone (extended-release) Morphine (extended-release) Opioid antagonists (Naltrexone Nalmefene) Benzodiazepine
Fosenazide
Opioid antagonist
was first reported in a patent in 1974. In the United States, immediate-release injectable nalmefene was approved in 1995, as an antidote for opioid overdose
Nalmefene
Combination drug formulation
many regards, be figuratively thought of as functional inverses of the morphine-like, euphoric and stress-inhibiting endorphins, induce dysphoria and stress-like
Buprenorphine/samidorphan
Receptor antagonist that acts on one or more of the opioid receptors
Jack Crawford's wife after she tries to commit suicide by overdosing on morphine. Theriot, Jonathan; Sabir, Sarah; Azadfard, Mohammadreza (2025), "Opioid
Opioid_antagonist
Opioid antagonist acting at the mu, kappa and delta receptors
Methadone Dihydrocodeine Dihydroetorphine Hydromorphone (extended-release) Morphine (extended-release) Opioid antagonists (Naltrexone Nalmefene) Benzodiazepine
Ondelopran
Chemical compound
ligand, which stimulates dopamine release to a moderate extent when administered alone, but reduces the dopamine release caused by methamphetamine. It also
Lobeline
Medical specialty that deals with the treatment of addiction
abuse Hospital (1901), the Emmanuel Clinic/the Emmanuel movement (1906), morphine maintenance clinics (1919–1924), narcotics farms (1935), Alcoholics Anonymous
Addiction_medicine
Opioid analgesic drug
strong painkiller for humans. It is several thousand times stronger than morphine (between 1000× and 12000× more potent depending what method is used for
Dihydroetorphine
Anti-convulsant, anti-addictive CNS stimulant alkaloid
alkaloids on morphine and cocaine self-administration in rats: relationship to tremorigenic effects and to effects on dopamine release in nucleus accumbens
Ibogamine
Synthetic opioid drug
Methadone Dihydrocodeine Dihydroetorphine Hydromorphone (extended-release) Morphine (extended-release) Opioid antagonists (Naltrexone Nalmefene) Benzodiazepine
Levacetylmethadol
1997 remix album by Michael Jackson
October 20, 2000, it was certified platinum in the US. "Morphine" Excerpt of the track "Morphine". Problems playing this file? See media help. The album
Blood on the Dance Floor: HIStory in the Mix
Blood_on_the_Dance_Floor:_HIStory_in_the_Mix
alcohol can occur over hours, last up to several days, or in the event of extended abuse, even weeks. Due to the long term effects of alcohol abuse, binge
Alcohol_and_society
Antihypertensive drug
Hypertension. 16 (7): 453–457. doi:10.1038/sj.jhh.1001416. PMID 12080428. "Press release: Targacept, Inc. Acquires Marketed Drug To Expand Its CNS Portfolio | Evaluate"
Mecamylamine
Chemical compound
Methadone Dihydrocodeine Dihydroetorphine Hydromorphone (extended-release) Morphine (extended-release) Opioid antagonists (Naltrexone Nalmefene) Benzodiazepine
Bemesetron
Medication used for opioid withdrawal
drug binds to the receptor to exert its activity. Lofexidine inhibits the release of norepinephrine in the central and peripheral nervous system, thereby
Lofexidine
Synthetic opioid
Methadone Dihydrocodeine Dihydroetorphine Hydromorphone (extended-release) Morphine (extended-release) Opioid antagonists (Naltrexone Nalmefene) Benzodiazepine
Levomethadone
Opioid drug used in pain relief
brain and spinal cord. Hydrocodone 10 mg is equivalent to about 10 mg of morphine by mouth. Hydrocodone was patented in 1923, while the long-acting formulation
Hydrocodone
1994 suicide of Nirvana singer and guitarist
typical heroin doses over an extended period) or a "free morphine" assay (a more specialized test that counts only the morphine molecules that have not yet
Suicide_of_Kurt_Cobain
Chemical compound
alkaloids on morphine and cocaine self-administration in rats: relationship to tremorigenic effects and to effects on dopamine release in nucleus accumbens
Tabernanthine
2004 studio album by Mark Sandman
started a record label of the same name. But when they tried to release Sandbox, Morphine's former label Rykodisc filed a lawsuit, claiming they owned several
Sandbox: The Music of Mark Sandman
Sandbox:_The_Music_of_Mark_Sandman
Antialcohol treatment
Methadone Dihydrocodeine Dihydroetorphine Hydromorphone (extended-release) Morphine (extended-release) Opioid antagonists (Naltrexone Nalmefene) Benzodiazepine
GET-73
Pharmaceutical drug classification
Methadone Dihydrocodeine Dihydroetorphine Hydromorphone (extended-release) Morphine (extended-release) Opioid antagonists (Naltrexone Nalmefene) Benzodiazepine
ATC_code_N
Dried latex of the opium poppy containing narcotic compounds
Approximately 12 percent of opium is made up of the analgesic alkaloid morphine, which is processed chemically to produce heroin and other synthetic opioids
Opium
Opioid analgesic of benzenoid class
metabolites. The potency of tapentadol is somewhere between that of tramadol and morphine, with an analgesic efficacy comparable to that of oxycodone despite a lower
Tapentadol
Chemical compound
Methadone Dihydrocodeine Dihydroetorphine Hydromorphone (extended-release) Morphine (extended-release) Opioid antagonists (Naltrexone Nalmefene) Benzodiazepine
DOV-102,677
Alcoholism drug
"Studies of four novel diphenylbutylpiperazinepyridyl derivatives on release and inhibition of reuptake of dopamine, serotonin and noradrenaline by
FG5865
Combination drug formulation
buprenorphine/naltrexone combination attenuates drug-primed reinstatement to cocaine and morphine in rats in a conditioned place preference paradigm" (PDF). Addiction Biology
Buprenorphine/naltrexone
Chemical compound
Methadone Dihydrocodeine Dihydroetorphine Hydromorphone (extended-release) Morphine (extended-release) Opioid antagonists (Naltrexone Nalmefene) Benzodiazepine
Dianicline
Chemical compound
Methadone Dihydrocodeine Dihydroetorphine Hydromorphone (extended-release) Morphine (extended-release) Opioid antagonists (Naltrexone Nalmefene) Benzodiazepine
Radafaxine
Combination drug
Methadone Dihydrocodeine Dihydroetorphine Hydromorphone (extended-release) Morphine (extended-release) Opioid antagonists (Naltrexone Nalmefene) Benzodiazepine
Tetrabamate
Pharmaceutical drug classification
Methadone Dihydrocodeine Dihydroetorphine Hydromorphone (extended-release) Morphine (extended-release) Opioid antagonists (Naltrexone Nalmefene) Benzodiazepine
ATC_code_N07
Chemical compound
Methadone Dihydrocodeine Dihydroetorphine Hydromorphone (extended-release) Morphine (extended-release) Opioid antagonists (Naltrexone Nalmefene) Benzodiazepine
Surinabant
Chemical compound
Methadone Dihydrocodeine Dihydroetorphine Hydromorphone (extended-release) Morphine (extended-release) Opioid antagonists (Naltrexone Nalmefene) Benzodiazepine
Thienorphine
Chemical compound
derived from morphine by replacing the N-methyl group with β-phenethyl. It is around eight to fourteen times more potent than morphine as a result of
N-Phenethylnormorphine
Drug
drugs including morphine, meperidine, fentanyl, methadone and buprenorphine, as well as some otherwise inactive metabolites like morphine-3-glucuronide
(+)-Naloxone
Substance for treatment of alcoholism
"Studies of four novel diphenylbutylpiperazinepyridyl derivatives on release and inhibition of reuptake of dopamine, serotonin and noradrenaline by
FG-5893
Chemical compound
Methadone Dihydrocodeine Dihydroetorphine Hydromorphone (extended-release) Morphine (extended-release) Opioid antagonists (Naltrexone Nalmefene) Benzodiazepine
Calcium_carbimide
2026 film by Nia DaCosta
repeatedly visits him. Kelson deduces that Samson is becoming addicted to the morphine from his blowgun, deliberately allowing himself to be drugged. Samson no
28 Years Later: The Bone Temple
28_Years_Later:_The_Bone_Temple
Discography of Australian rock band DMA's
September 2016). "DMA's share heartbreaking music video for "Step Up the Morphine"". Tone Deaf. Retrieved 7 March 2020. "ARIA Charts – Accreditations – 2024
DMA's_discography
Opioid analgesic drug
30 minutes and lasts about 3–4 hours for immediate-release tablets and 12 hours for extended-release tablets. The elimination half-life of oxymorphone
Oxymorphone
Danish nurse and criminal (born 1984)
given her sick and weak patients lethal doses of morphine and diazepam. The case in the city court extended over 27 days and involved more than 70 witnesses
Christina_Aistrup_Hansen
Irish actress (born 1993 or 1994)
Journey Into Night review – Brian Cox upstaged by Patricia Clarkson's morphine fiend". The Guardian. Retrieved 7 April 2024. Louisa Harland, for her part
Louisa_Harland
Calcium channel blocker medication
signaling in the brain. Diltiazem also enhances the analgesic effect of morphine in animal tests, without increasing respiratory depression, and reduces
Diltiazem
Drug
itself but blocks the antiaggressive effect of 5-HT1B agonists, and alters release of serotonin in the brain, as well as reducing drug-seeking behaviour in
GR-127935
Chemical compound
(R)-coronaridine and (S)-coronaridine can decrease intake of cocaine and morphine in animals and it may have muscle relaxant and hypotensive activity. Coronaridine
Coronaridine
Organic chemical that functions both as a hormone and a neurotransmitter
or change levels of satiation. However, opiate drugs such as heroin and morphine produce increases in expressions of "liking" and "wanting" behaviors. Moreover
Dopamine
Opioid analgesic and antitussive drug
nicocodeine is turned into morphine as noted above. Nicocodeine cough medicines are available as syrups, extended-release syrups, and sublingual drops
Nicocodeine
Synthetic opioid pain medication
immediate-release formulation. On a dose-by-dose basis, tramadol has about one-tenth the potency of morphine (thus 100 mg is commensurate with 10 mg morphine but
Tramadol
maintained ties to the Jackson 5 and Motown. Between 1972 and 1975, Michael released four solo studio albums with Motown: Got to Be There (1972), Ben (1972)
List of songs recorded by Michael Jackson
List_of_songs_recorded_by_Michael_Jackson
screaming. Melissa McCall and Geyer attempt to help him, pumping him full of morphine to no effect. Melissa calls Scott and Kira to the hospital, and Scott siphons
List of Teen Wolf (2011 TV series) secondary characters
List_of_Teen_Wolf_(2011_TV_series)_secondary_characters
Organic compound involved in immune responses
alkaloids, including such drugs as morphine, and curare alkaloids, can displace histamine in granules and cause its release. Antibiotics like polymyxin are
Histamine
American musician (1947–1975)
"Song to the Siren." Buckley died at the age of 28 from a heroin and morphine overdose. He left behind one biological son, Jeff Buckley, who himself
Tim_Buckley
2013 film by David Twohy
Riddick. After they reach the power nodes, Riddick reveals Johns's son's morphine addiction and his attempts to use a child as bait. Diaz attacks Riddick
Riddick_(film)
Chemical compound
inhibitor of serotonin, dopamine, and norepinephrine, and also has some weak releasing activity. In clinical trials pridefine was found to be as efficacious
Pridefine
1971 studio album by the Rolling Stones
Horses". "Sister Morphine", cut during Let It Bleed's sessions earlier in March of that year, had been held over from that release. Much of the recording
Sticky_Fingers
Toxicity due to excessive consumption of opiates
overdose is toxicity due to excessive consumption of opioids, such as morphine, codeine, heroin, fentanyl, tramadol, Oxycodone, and methadone. This preventable
Opioid_overdose
Central nervous system stimulant
immediate-release and extended-release formulations costing US$1.90 for a strip of immediate-release and US$2.90 for a strip of AddWize extended-release Clockwise
Methylphenidate
Form of behavioral dependence involving emotional symptoms
and psychological dependence signs and voluntary morphine consumption in morphine-dependent and morphine-withdrawn rats". Behavioural Pharmacology. 27 (2
Psychological_dependence
"Effects of Alcohol on the Pharmacokinetics of Morphine Sulfate and Naltrexone Hydrochloride Extended Release Capsules". The Journal of Clinical Pharmacology
Dose_dumping
EXTENDED RELEASE-MORPHINE
EXTENDED RELEASE-MORPHINE
EXTENDED RELEASE-MORPHINE
EXTENDED RELEASE-MORPHINE
EXTENDED RELEASE-MORPHINE
EXTENDED RELEASE-MORPHINE
EXTENDED RELEASE-MORPHINE
EXTENDED RELEASE-MORPHINE
EXTENDED RELEASE-MORPHINE