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Protein-coding gene in the species Homo sapiens
Cytochrome P450 4F8 is a protein that in humans is encoded by the CYP4F8 gene. This gene, CYP4F8, encodes a member of the cytochrome P450 superfamily of enzymes
CYP4F8
Protein-coding gene in the species Homo sapiens
long chain fatty acids by recombinant CYP4F8 and CYP4F12 and catalytic importance of Tyr-125 and Gly-328 of CYP4F8". Archives of Biochemistry and Biophysics
CYP4F12
List of Cytochrome P450 enzymes
20-diHETE, EETs to 20-hydroxy-EETs, and lipoxins to 20-hydroxy products. CYP4F8 and CYP4F12 metabolize PUFAs to signaling molecules: they metabolizes EPA
Cytochrome P450 (individual enzymes)
Cytochrome_P450_(individual_enzymes)
Class of compounds
by mammalian, including human, tissues. The same CYPs but also CYP4A1, CYP4F8, and CYP4F12 metabolize eicosapentaenoic acid to five epoxide epoxyeicosatetraenoic
Eicosanoid
P13584 3889 CYP4F2 HGNC:2645; P78329 3890 CYP4F3 HGNC:2646; Q08477 3891 CYP4F8 HGNC:2648; P98187 3892 CYP4F11 HGNC:13265; Q9HBI6 3893 CYP4F12 HGNC:18857;
List of human protein-coding genes 2
List_of_human_protein-coding_genes_2
Chemical compound
smaller amounts of 17S,18R-EEQ. In addition to the cited CYP's, CYP4A11, CYP4F8, CYP4F12, CYP1A1, CYP1A2, and CYP2E1, which are classified as CYP monooxygenase
Epoxyeicosatetraenoic_acid
Set of cytochrome P450 enzymes
CYP2C19, CYP2E1, CYP2J2, CYP2S1, CYP3A4, CYP4F2, CYP4F3A, CYP4F3B, CYP4A11, CYP4F8, and CYP4F12. CYP2C8 and CYP2C9 form particularly large amounts of superoxide
Epoxygenase
Group of chemical compounds
CYP2C18, CYP2E1, CYP4A11, CYP4F8, and CYP4F12 also metabolize DHA to EDPs. CYP2C8, CYP2C18, CYP2E1, CYP2J2, VYP4A11, CYP4F8, and CYP4F12 preferentially
Epoxydocosapentaenoic_acid
Class of fatty acids
are the main producers of EETs although CYP2C9, CYP2C18, CYP3A4, CYP4A11, CYP4F8, and CYP4F12 are capable of producing the EETs and may do so in certain
Epoxyeicosatrienoic_acid
Human enzyme
activities. Other CYP4F subfamily members have related but distinct roles: CYP4F8 and CYP4F12 metabolize prostaglandins and arachidonic acid, while CYP4F11
CYP4F2
Chemical compound
However, CYP2U1 may also contribute to the production of these two HETEs and CYP4F8 can metabolize arachidonic acid to 19-HETE while forming little or no 20-HETE
20-Hydroxyeicosatetraenoic acid
20-Hydroxyeicosatetraenoic_acid
Protein-coding gene in the species Homo sapiens
cytochrome P450 genes on chromosome 19. Another member of this family, CYP4F8, is approximately 18 kb away. Both variants localize on the endoplasmic
CYP4F3
CYP4F8
CYP4F8
CYP4F8
CYP4F8
CYP4F8
CYP4F8
CYP4F8
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CYP4F8