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Increase of the total mass of a cell
Cell growth refers to an increase in the total mass of a cell, including both cytoplasmic, nuclear and organelle volume. Cell growth occurs when the overall
Cell_growth
Biological process of growth and division
exponential increase in cell number and is therefore a rapid mechanism of tissue growth. Cell proliferation requires both cell growth and cell division to occur
Cell_proliferation
Growth of bacterial colonies
the resulting daughter cells are genetically identical to the original cell. Hence, bacterial growth occurs. Both daughter cells from the division do not
Bacterial_growth
Chemical compound
with mice and transplanted tumors (from human lung carcinoma SPC-A1 cells), tumor growth remained suppressed for up to 21 days during treatment with gambogic
Gambogic_acid
Solid, liquid or gel used to grow microorganisms or cells
A growth medium or culture medium is a solid, liquid, or semi-solid designed to support the growth of a population of microorganisms or cells via the
Growth_medium
Process by which cells are grown under controlled conditions
growth factors, hormones, and gases (CO2, O2), and regulates the physio-chemical environment (pH buffer, osmotic pressure, temperature). Most cells require
Cell_culture
Outermost layer of some cells
properties, and form may change during the cell cycle and depend on growth conditions. In most cells, the cell wall is flexible, meaning that it will bend
Cell_wall
Protein found in humans
stimulation by growth hormone (GH). It is a key mediator of anabolic activities in numerous tissues and cells, such as growth hormone-stimulated growth, metabolism
Insulin-like_growth_factor_1
Protein-coding gene in the species Homo sapiens
performs many cellular functions, including the control of cell growth, cell proliferation, cell differentiation, and apoptosis. In humans, TGF-β1 is encoded
TGF_beta_1
Protein-coding gene in mammals
throughout the body including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. FGFs act through a family of four
Fibroblast_growth_factor_21
Tumor cell
for growth and repair. A parent cell divides to form two daughter cells, and these daughter cells are used to build new tissue or to replace cells that
Cancer_cell
Biological process in primates
"Activation and function of the epidermal growth factor receptor and erbB-2 during mammary gland morphogenesis". Cell Growth Differ. 9 (9): 777–85. PMID 9751121
Breast_development
Organelle in eukaryotic cells responsible for respiration
signaling, cellular differentiation, and cell death, as well as maintaining control of the cell cycle and cell growth. Mitochondrial biogenesis is in turn
Mitochondria
Transmembrane protein
proteins. Ostensibly, by halting the signaling cascade in cells that rely on this pathway for growth, tumor proliferation and migration are diminished. Gefitinib
Epidermal growth factor receptor
Epidermal_growth_factor_receptor
Protein that stimulates cell division and differentiation
Epidermal growth factor (EGF) is a protein that stimulates cell growth and differentiation by binding to its receptor, EGFR. Human EGF is 6-kDa and has
Epidermal_growth_factor
Signaling glycoprotein regulating cell proliferation
Platelet-derived growth factor (PDGF) is one among numerous growth factors that regulate cell growth and division. In particular, PDGF plays a significant
Platelet-derived growth factor
Platelet-derived_growth_factor
Protein or other substance that stimulates cellular proliferation
A growth factor is a naturally occurring substance capable of stimulating cell proliferation, wound healing, and occasionally cellular differentiation
Growth_factor
Protein-coding gene in humans
exchanger 2 is a growth-related cell surface protein. It was identified because it reacts with the monoclonal antibody K1 in cells, such as the ovarian
Ecto-NOX disulfide-thiol exchanger 2
Ecto-NOX_disulfide-thiol_exchanger_2
Rate of turnover of molecules in a metabolic pathway
needs of the building blocks and Gibbs free energy in conjunction with cell growth. There is therefore tight regulation of the fluxes through the central
Flux_(metabolism)
Protein involved in blood vessel growth
endothelial growth factor (VEGF, /vɛdʒˈɛf/), originally known as vascular permeability factor (VPF), is a signal protein produced by many cells that stimulates
Vascular endothelial growth factor
Vascular_endothelial_growth_factor
Events leading to cell division
to its division into two daughter cells. These events include the growth of the cell, duplication of its DNA (DNA replication) and some of its organelles
Cell_cycle
Benign or malignant neoplasm involving the stomach
occur within the cell cycle to cause abnormal cell growth. The first error is unscheduled proliferation, which essentially refers to the cell continuing to
Tumors_of_the_stomach
Stem cells that give rise to other blood cells
therapeutically. Hematopoietic stem cells, like all adult stem cells, mostly exist in a state of quiescence, or reversible growth arrest. The altered metabolism
Hematopoietic_stem_cell
Protein-coding gene in the species Homo sapiens
Kleer CG (March 2012). "On how CCN6 suppresses breast cancer growth and invasion". J Cell Commun Signal. 6 (1): 5–10. doi:10.1007/s12079-011-0148-9. PMC 3271195
Cellular communication network factor 6
Cellular_communication_network_factor_6
Underdevelopment of a tissue or organ
hyperplasia generally refers to excessive cell growth later in life. (Atrophy, the wasting away of already existing cells, is technically the direct opposite
Hypoplasia
Gene that has the potential to cause cancer
those cells designated for apoptosis to survive and proliferate instead. Most oncogenes began as proto-oncogenes, normal genes involved in cell growth and
Oncogene
Protein found in humans
adenocarcinoma cell line A549 overexpression of IRS-1 leads to reduced growth. Tumor infiltrating neutrophils have recently been thought to adjust tumor growth and
Insulin_receptor_substrate_1
Informal group of fungi
the asymmetric division process known as budding. With their single-celled growth habit, yeasts can be contrasted with molds, which grow hyphae. Fungal
Yeast
Communications in cell biology
between cells and the extracellular matrix. The loss of communication between cells can result in uncontrollable cell growth and cancer. Stable cell-cell interactions
Cell–cell_interaction
Family of proteins involved in anatomical development
Fibroblast growth factors (FGF) are a family of cell signalling proteins produced by the macrophages. They are involved in a wide variety of processes
Fibroblast_growth_factor
Empirical model of the evolution of a population or biomass over time
was measured during the course of an 8-hour cell growth experiment. The observed pattern of bacterial growth is bi-phasic because two different sugars were
Growth_curve_(biology)
growth rate of the cells within the bioreactor. This is often confused with substrate limitation, which describes environments in which cell growth is
Substrate inhibition in bioreactors
Substrate_inhibition_in_bioreactors
Human immortalised myelogenous leukemia cell line
K562 cells in terms of growth, cell differentiation, and apoptosis. The growth of these leukemic cells are controlled by either initiating cell differentiation
K562_cells
Mass of cells which cannot spread throughout the body
tumors, benign tumors generally have a slower growth rate. Benign tumors have relatively well differentiated cells. They are often surrounded by an outer surface
Benign_tumor
Mammalian protein found in humans
suggests, NGF is involved primarily in the growth, as well as the maintenance, proliferation, and survival of nerve cells (neurons) and is critical for the survival
Nerve_growth_factor
process of growth to maturity. The process begins with fertilization, where an egg released from the ovary of a female is penetrated by a sperm cell from a
Development_of_the_human_body
Inhibition of cell growth and proliferation
Cytostasis (cyto – cell; stasis – stoppage) refers to the inhibition of cell growth and proliferation. A cytostatic agent is a cellular component or drug
Cytostasis
Topics referred to by the same term
up growth in Wiktionary, the free dictionary. Growth may refer to: Auxology, the study of all aspects of human physical growth Bacterial growth Cell growth
Growth
Immunological condition
Mast cell activation syndrome (MCAS) is one type of mast cell activation disorder (MCAD). MCAS is an immunological condition in which mast cells, a type
Mast_cell_activation_syndrome
Chemical compounds that regulate plant growth and development
foliage. Not all plant cells respond to hormones, but those cells that do are programmed to respond at specific points in their growth cycle. The greatest
Plant_hormone
Quality of being toxic to cells
growth and proliferation without causing cell death. Cytotoxic agents can induce a range of cellular responses, including inhibition of cell growth,
Cytotoxicity
Protein-coding gene in the species Homo sapiens
growth factor-1, and Endothelial cell growth factor-1. Gene sequencing revealed that this group was actually the same growth factor and that FGF1 was a member
Fibroblast_growth_factor_1
Human disease that results in excess growth of certain parts of the body
pituitary cells; it permanently switches on the signal that tells the cell to divide and secrete growth hormones. The events within the cell that cause
Acromegaly
Use of stem cells to treat or prevent a disease or condition
Stem-cell therapy uses stem cells to treat or prevent a disease or condition. As of 2024[update], the only FDA-approved therapy using stem cells is hematopoietic
Stem-cell_therapy
Cell line derived from human embryonic kidney cells
HEK 293 cell line has been widely used in research for decades due to its reliable and fast growth and propensity for transfection. The cell line is used
HEK_293_cells
Group of diseases involving cell growth
Cancer is a group of diseases involving uncontrolled cell growth typically resulting in tumors with the potential to invade or spread to other parts of
Cancer
Mammalian protein found in humans
a serine-threonine protein kinase that regulates cell growth, cell proliferation, cell motility, cell survival, protein synthesis, autophagy, and transcription
MTOR
Mammalian protein found in Homo sapiens
response to MET-expressing tumor cells, or actively by stimulating immune cells and altering differentiation/growth of tumor cells. Administering monoclonal
Hepatocyte growth factor receptor
Hepatocyte_growth_factor_receptor
Tumor suppressor gene
activation of the Akt/PKB signaling pathway, an important pathway in cell growth, survival, and proliferation.[citation needed] PTEN protein is primarily
PTEN_(gene)
Growth factor and signaling protein otherwise known as FGF2
variants were isolated: 'basic FGF' (FGF2); Heparin-binding growth factor-2; and Endothelial cell growth factor-2. Gene sequencing revealed that this group is
Fibroblast_growth_factor_2
Protein-coding gene in the species Homo sapiens
components in the cell cycle, which indicates its role in cell growth. Recently, STAU1-mediated post-transcriptional regulation of cell cycle mRNAs showed
STAU1
First subphase of interphase
or growth 1 phase, is the first of four phases of the cell cycle that takes place in eukaryotic cell division. In this part of interphase, the cell synthesizes
G1_phase
Surface on which a plant or animal lives
vertebrate cells that require support for their growth in vitro otherwise they will not grow properly. Such cells are called anchorage-dependent cells. Therefore
Substrate_(biology)
Mammalian protein and protein-coding gene
tyrosine-protein kinase KIT, CD117 (cluster of differentiation 117) or mast/stem cell growth factor receptor (SCFR). Multiple transcript variants encoding different
KIT_gene
Cell signaling pathway
mitogens such as epidermal growth factor (EGF) into signaling events promoting cell growth and proliferation in many mammalian cell types. In a simplified
MAPK/ERK_pathway
Animal flesh produced by culturing cells
meat is produced by culturing animal cells in vitro. This production method involves the molecularly identical growth of animal flesh, outside of a living
Cultured_meat
Phenomenon characterized by the cessation of cell division
events, abnormal cellular growth, oxidative stress, autophagy factors, among many other things. The physiological importance of cell senescence has been attributed
Cellular_senescence
GTP-binding proteins functioning on cell-cycle regulation
overactive signaling inside the cell, even in the absence of incoming signals. Because these signals result in cell growth and division, overactive Ras signaling
Ras_GTPase
Mammalian protein found in Homo sapiens
Hepatocyte growth factor (HGF) or scatter factor (SF) is a paracrine cellular growth, motility and morphogenic factor. It is secreted by mesenchymal cells and
Hepatocyte_growth_factor
Cell surface receptors
Platelet-derived growth factor receptors (PDGF-R) are cell surface tyrosine kinase receptors for members of the platelet-derived growth factor (PDGF) family
Platelet-derived growth factor receptor
Platelet-derived_growth_factor_receptor
Chemical compound
1977, the growth modulating peptide was shown to be a glycyl-L-histidyl-L-lysine. It is proposed that GHK-Cu modulates copper intake into cells. In the
Copper_peptide_GHK-Cu
Tumor or other abnormal growth of tissue
oncology. Prior to the abnormal growth of tissue, such as neoplasia, cells often undergo an abnormal pattern of growth, such as metaplasia or dysplasia
Neoplasm
Type of microRNA
miR-324-5p is a microRNA that functions in cell growth, apoptosis, cancer, epilepsy, neuronal differentiation, psychiatric conditions, cardiac disease
MiR-324-5p
Genus of green algae
threat can be so significant that the cells will coalesce into these eight-cell colonies even in severely limiting growth conditions in order to reduce grazing
Scenedesmus
Effector molecule that inhibits cell growth and promotes cellular differentiation
effector molecules that induce changes in cell chemistry, inhibiting growth and promoting differentiation of cell type. This name has been given to several
Differentiation-inducing factor
Differentiation-inducing_factor
Academic journal
Association for Cancer Research. Prior to September 2002 it was known as Cell Growth & Differentiation. Official website Cell Growth & Differentiation v t e
Molecular_Cancer_Research
Two important groups of soluble factors
B Cell Growth and Differentiation Factors (also known as BCGF and BCDF) are two important groups of soluble factors controlling the life cycle of B cells
B cell growth and differentiation factors
B_cell_growth_and_differentiation_factors
Enzyme
deoxyribosyltransferase, animal growth regulators, blood platelet-derived endothelial cell, growth factors, blood platelet-derived endothelial cell growth factor, deoxythymidine
Thymidine_phosphorylase
Protein-coding gene in the species Homo sapiens
LY (Dec 2001). "Modulation of endothelial cell growth arrest and apoptosis by vascular endothelial growth inhibitor". Circulation Research. 89 (12):
Vascular endothelial growth inhibitor
Vascular_endothelial_growth_inhibitor
Medical condition
helix-loop-helix transcription factors mediate human mesenchymal stem cell growth and commitment". Stem Cells. 27 (10): 2457–68. doi:10.1002/stem.181. PMID 19609939
Barber–Say_syndrome
Gene that inhibits tumorigenic phenotype
directly regulate cell growth by either inhibiting cell cycle progression or inducing apoptosis. Lastly, landscaper genes regulate growth by contributing
Tumor_suppressor_gene
Basic unit of life forms
single cell, the mother cell divides into two daughter cells. This leads to the growth of tissue in multicellular organisms. Prokaryotic cells divide
Cell_(biology)
Type of cellular growth
Diauxic growth, diauxie or diphasic growth is any cell growth characterized by cellular growth in two phases. Diauxic growth, meaning double growth, is caused
Diauxic_growth
Human protein-coding gene
Platelet-derived growth factor receptor A, also termed CD140a, is a receptor located on the surface of a wide range of cell types. The protein is encoded
Platelet-derived growth factor receptor A
Platelet-derived_growth_factor_receptor_A
Plant growth in reaction to gravity and bending of leaves and roots
growth during tropisms mainly involves changes in cell expansion versus changes in cell division, although a role for cell division in tropic growth has
Gravitropism
Type of immune cell
activation and growth of cytotoxic T cells, and in maximizing bactericidal activity of phagocytes such as macrophages and neutrophils. CD4+ cells are mature
T_helper_cell
Development and formation of the human embryo
entails growth from a one-celled zygote to an adult human being. Fertilization occurs when the sperm cell successfully enters and fuses with an egg cell (ovum)
Human_embryonic_development
Protein-coding gene in the species Homo sapiens
expression and thereby reduces breast cancer cell line cell growth. Normal cells and some breast cancer cells have receptors that bind estrogen and progesterone
DACH1
Protein found in humans
the fibroblast growth factor receptor (FGFR) family, which in addition to FGFR1, includes FGFR2, FGFR3, FGFR4, and FGFRL1. FGFR1-4 are cell surface membrane
Fibroblast growth factor receptor 1
Fibroblast_growth_factor_receptor_1
Protein-coding gene in the species Homo sapiens
cytoplasmic protein involved in stress responses, hormone responses, cell growth, and differentiation. In humans, NDRG1 gene is located on the long arm
NDRG1
Biological process
Cell division is the process by which a parent cell divides into two daughter cells. Cell division usually occurs as part of a larger cell cycle in which
Cell_division
Mammalian protein found in Homo sapiens
hematopoietic progenitor cells, such as megakaryocyte progenitors, in vitro. In addition, it works with other cytokines to support the colony growth of BFU-E, CFU-GM
Stem_cell_factor
Direct extension and penetration by cancer cells into neighboring tissues
invasive growth are distinguished based on specific morphological and molecular genetic parameters: single-cell migration and collective cell migration
Invasion_(cancer)
Group of blood-based disorders
characterized by the development and growth of a pre-malignant or malignant population of eosinophils, a type of white blood cell that occupies the bone marrow
Clonal_hypereosinophilia
Tendency of a medical condition to become progressively worse
mechanism of cell transformation. This cell transformation can occur through either "DNA integration or cellular-DNA alteration of growth regulator genes"
Malignancy
Mammalian protein found in humans
with human epidermal growth factor receptor 1, or HER1. The Neu alias of HER2 derives its name from the parent glioblastoma cell line - a type of neural
HER2
Protein involved in blood vessel growth
cell growth, promoting cell migration, and inhibiting apoptosis. Alternatively spliced transcript variants, encoding either freely secreted or cell-associated
Vascular endothelial growth factor A
Vascular_endothelial_growth_factor_A
Unspecialized biological cell that can become specialized
Self-renewal: the ability to go through numerous cycles of cell growth and cell division, known as cell proliferation, while maintaining the undifferentiated
Stem_cell
Skin cancer originating in melanocytes
Human Endogenous Retroviruses (HERVs), Inhibit Cell Growth, and Reduce Invasive Capability in Melanoma Cell Lines". International Journal of Molecular Sciences
Melanoma
Small molecules that inhibit the Hedgehog signaling pathway
cancer stem cell maintenance across cancer types, inhibition of the Hedgehog signaling pathway can be a useful strategy for restricting tumor growth and for
Hedgehog_pathway_inhibitor
Individual living life form
germ-soma specialisation, with some insects reproducing, others not, like cells in an animal's body. The body of a siphonophore, a jelly-like marine animal
Organism
Chemical compound (polypeptide neurotransmitter)
turn, induce SP and the NK1 receptor. SP is particularly excitatory to cell growth and multiplication, via usual, as well as oncogenic drivers. SP is a
Substance_P
Series of molecular interactions within a cell that produces some outcome
through biochemical reactions. They are involved in processes such as cell growth and development. These pathways can trigger the assembly of new molecules
Biological_pathway
Growth of quantities at rate proportional to the current amount
exponential growth indicates constant growth rate, it is frequently assumed that exponentially growing cells are at a steady-state. However, cells can grow
Exponential_growth
Protein-coding gene in the species Homo sapiens
development (alternative names: Glioblastoma-derived T-cell suppressor factor, G-TSF, BSC-1 cell growth inhibitor, Polyergin, Cetermin). It is an extracellular
TGF_beta_2
Class of enzymes
biological cells which enables the separation of daughter cells following cell division. They are involved in cell growth, cell wall metabolism, cell division
Autolysin
Species of alga
the resting cells, which are produced and rapidly accumulated when the environmental conditions become unfavorable for normal cell growth. Examples of
Haematococcus_lacustris
Chemical compound
an electrochemical gradient in the cell wall. The acidity increases from 6 to 4.5-6 and according to the acid growth hypothesis, it ensures the activation
Brassinolide
Formation of cancer
of regulation of tissue growth. In order for a normal cell to transform into a cancer cell, genes that regulate cell growth and differentiation must
Carcinogenesis
Study of cell activity
by the same vesicle. Betts, J. Gordon; et al. (April 25, 2013). "3.5 Cell Growth and Division". Anatomy and Physiology. OpenStax. p. 20. ISBN 978-1-938168-13-0
Cell_physiology
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