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CD44

  • CD44
  • Cell-surface glycoprotein

    The CD44 antigen is a cell-surface glycoprotein involved in cell–cell interactions, cell adhesion and migration. In humans, the CD44 antigen is encoded

    CD44

    CD44

    CD44

  • Hyaluronic acid
  • Physiological molecule and therapeutic drug

    interaction with CD44. Receptor CD44 participates in cell adhesion interactions required by tumor cells. Although hyaluronan binds to receptor CD44, there is

    Hyaluronic acid

    Hyaluronic acid

    Hyaluronic_acid

  • Extracellular matrix
  • Structural support for biological cells

    tumor development. It interacts with a specific transmembrane receptor, CD44. Chitin, a polymer of N-acetyl glucosamine, is not produced by mammals but

    Extracellular matrix

    Extracellular matrix

    Extracellular_matrix

  • Heterogeneous ribonucleoprotein particle
  • Macromolecular complex containing protein and RNA molecules

    proteins. hnRNP has been shown to regulate CD44, a cell-surface glycoprotein, through splicing mechanisms. CD44 is involved in cell-cell interactions and

    Heterogeneous ribonucleoprotein particle

    Heterogeneous ribonucleoprotein particle

    Heterogeneous_ribonucleoprotein_particle

  • Cancer stem cell
  • Cancer cells with features of normal cells

    Both CD44+CD24− and CD44+CD24+ cell populations are tumor initiating cells; however, CSC are most highly enriched using the marker profile CD44+CD49fhiCD133/2hi

    Cancer stem cell

    Cancer stem cell

    Cancer_stem_cell

  • Hyaluronidase
  • Class of enzymes

    cleaving high-molecular weight hyaluronic acid, which is mostly bound to the CD44 receptor. The resulting hyaluronic acid fragments of variable size are then

    Hyaluronidase

    Hyaluronidase

    Hyaluronidase

  • Competing endogenous RNA
  • transcript abundance and accelerates cell growth. The CD44 3'UTR has been shown to regulate expression of the CD44 protein and cell cycle regulation protein, CDC42

    Competing endogenous RNA

    Competing_endogenous_RNA

  • Bivatuzumab
  • Chemical compound

    Bivatuzumab (previously BIWA 4) is a humanized monoclonal antibody against CD44 v6. It is officially described as "immunoglobulin G1 (human-mouse monoclonal

    Bivatuzumab

    Bivatuzumab

  • Indian blood group system
  • Human blood group system

    on the presence or absence of inherited antigens that reside within the CD44 molecule that is expressed on the surface of blood cells. It is named so

    Indian blood group system

    Indian_blood_group_system

  • T cell
  • Type of white blood cell

    neither the CD4 nor CD8 co-receptor. The newly arrived CLP cells are CD4−CD8−CD44+CD25−ckit+ cells, and are termed early thymic progenitor (ETP) cells. These

    T cell

    T cell

    T_cell

  • Mechanotransduction
  • Conversion of mechanical stimulus of a cell into electrochemical activity

    mechanoreceptors include stretch-activated ion channels (SAC), the hyaluronan receptor CD44, annexin V (a collagen type II receptor), and integrin receptors (of which

    Mechanotransduction

    Mechanotransduction

    Mechanotransduction

  • Katherine A. Fitzgerald
  • Irish-born American molecular biologist and virologist

    Fitzgerald, Katherine (1999). Signal transduction processes regulating CD44 expression and CD44-mediated changes in pro-inflammatory gene expression (Thesis).

    Katherine A. Fitzgerald

    Katherine_A._Fitzgerald

  • Memory T cell
  • Subset of T lymphocytes

    (CD62L). Central memory T cells also have intermediate to high expression of CD44. This memory subpopulation is commonly found in the lymph nodes and in the

    Memory T cell

    Memory_T_cell

  • Elachista ornithopodella
  • Species of moth

    303529 EUNIS: 300702 Fauna Europaea: 435520 Fauna Europaea (new): 9ae68c46-cd44-41b1-b381-c2e07e250919 GBIF (old): 1833013 iNaturalist: 1048507 Insecta.pro:

    Elachista ornithopodella

    Elachista ornithopodella

    Elachista_ornithopodella

  • LYVE1
  • Region of a specific protein

    hyaladherin, a protein capable of binding to hyaluronic acid (HA), homologous to CD44, the main HA receptor. In humans it is encoded by the LYVE1 gene. LYVE1 is

    LYVE1

    LYVE1

    LYVE1

  • California's 44th congressional district
  • U.S. House district for California

    RAND California Election Returns: District Definitions California Voter Foundation map - CD44 33°51′N 118°15′W / 33.85°N 118.25°W / 33.85; -118.25

    California's 44th congressional district

    California's 44th congressional district

    California's_44th_congressional_district

  • Human iron metabolism
  • Iron metabolism in the body

    upregulation of CD44, a surface molecule capable of internalizing iron bound to the hyaluronan complex. This alternative pathway, relying on CD44-mediated endocytosis

    Human iron metabolism

    Human iron metabolism

    Human_iron_metabolism

  • Hyaladherin
  • hyaladherins belong to the Link module superfamily, including its main receptor CD44, hyalectans and TSG-6. In addition there is a diverse group of hyaladherins

    Hyaladherin

    Hyaladherin

  • Bivatuzumab mertansine
  • Chemical compound

    Monoclonal antibody Type Whole antibody Source Humanized (from mouse) Target CD44 v6 Clinical data ATC code none Identifiers ChemSpider none  NY (what is this

    Bivatuzumab mertansine

    Bivatuzumab mertansine

    Bivatuzumab_mertansine

  • Glioblastoma
  • Aggressive type of brain cancer

    with neural progenitor cells, both expressing the surface receptor CD133. CD44 can also be used as a cancer stem cell marker in a subset of glioblastoma

    Glioblastoma

    Glioblastoma

    Glioblastoma

  • Pauline Johnson (immunologist)
  • English immunologist and microbiologist

    the mechanisms regulating the interactions of the cell adhesion molecule CD44 with the matrix component, hyaluronan. Her research in 2020 uses mouse models

    Pauline Johnson (immunologist)

    Pauline_Johnson_(immunologist)

  • Central tolerance
  • Elimination of autoreactive lymphocytes by the immune system

    be distinguished by the expression of surface markers CD44 and CD25, with the DN1 cells being CD44+ CD25-. Similarly to the TSPs, the DN1 cells are still

    Central tolerance

    Central_tolerance

  • Thymocyte
  • Premature form of T cells present in the thymus

    are likely the precursors of at least some thymocytes. ELPs are Lineage-CD44+CD25-CD117+ and thus closely resemble ETPs, the earliest progenitors in the

    Thymocyte

    Thymocyte

  • Retinal ganglion cell
  • Type of cell within the eye

    express the cell surface antigen stage-specific embryonic antigen (SSEA)-1 and CD44 will form an inverted V-shape. They will establish the posterior aspect of

    Retinal ganglion cell

    Retinal ganglion cell

    Retinal_ganglion_cell

  • Fibronectin
  • Protein involved in cell adhesion, cell growth, cell migration and differentiation

    fibroblasts and endothelial cells. Fibronectin has been shown to interact with: CD44 COL7A1, LPA, IGFBP3, TNC, and TRIB3. Fetal fibronectin Fibronectin type I

    Fibronectin

    Fibronectin

    Fibronectin

  • CLEC9A
  • Protein-coding gene in humans

    CD32 A B CD33 CD34 CD35 CD36 CD37 CD38 CD39 CD40 CD41 CD42 a b c d CD43 CD44 CD45 CD46 CD47 CD48 CD49 a b c d e f CD50 51–100 CD51 CD52 CD53 CD54 CD55

    CLEC9A

    CLEC9A

    CLEC9A

  • B-cell activating factor
  • Mammalian protein found in Homo sapiens

    CD32 A B CD33 CD34 CD35 CD36 CD37 CD38 CD39 CD40 CD41 CD42 a b c d CD43 CD44 CD45 CD46 CD47 CD48 CD49 a b c d e f CD50 51–100 CD51 CD52 CD53 CD54 CD55

    B-cell activating factor

    B-cell activating factor

    B-cell_activating_factor

  • CEMIP
  • Protein-coding gene in the species Homo sapiens

    bind hyaluronic acid and catalyze its depolymerization independently of CD44 and hyaluronidases. Such function has also been validated in mice. CEMIP

    CEMIP

    CEMIP

    CEMIP

  • Complement receptor 2
  • Protein found in humans

    CD32 A B CD33 CD34 CD35 CD36 CD37 CD38 CD39 CD40 CD41 CD42 a b c d CD43 CD44 CD45 CD46 CD47 CD48 CD49 a b c d e f CD50 51–100 CD51 CD52 CD53 CD54 CD55

    Complement receptor 2

    Complement receptor 2

    Complement_receptor_2

  • CD226
  • Protein found in humans

    CD32 A B CD33 CD34 CD35 CD36 CD37 CD38 CD39 CD40 CD41 CD42 a b c d CD43 CD44 CD45 CD46 CD47 CD48 CD49 a b c d e f CD50 51–100 CD51 CD52 CD53 CD54 CD55

    CD226

    CD226

    CD226

  • CD164
  • Protein found in humans

    CD32 A B CD33 CD34 CD35 CD36 CD37 CD38 CD39 CD40 CD41 CD42 a b c d CD43 CD44 CD45 CD46 CD47 CD48 CD49 a b c d e f CD50 51–100 CD51 CD52 CD53 CD54 CD55

    CD164

    CD164

    CD164

  • Hyaluronan-mediated motility receptor
  • Protein-coding gene in the species Homo sapiens

    is less well studied than the main hyaluronan (HA) receptor, CD44. In contrast to CD44 and other cell-surface receptors which contain the classical membrane

    Hyaluronan-mediated motility receptor

    Hyaluronan-mediated motility receptor

    Hyaluronan-mediated_motility_receptor

  • MMP14
  • Protein-coding gene in the species Homo sapiens

    catalytic activity, MMP14 interacts with cell surface molecules (such as CD44 and integrins) to modulate cell signaling and behavior. Studies in knockout

    MMP14

    MMP14

    MMP14

  • Myofibroblast
  • Cell type with functions of both muscular and fibrous connective tissue

    myofibroblast differentiation pathway have been described, including hyaluronan and CD44 co-receptor activation of EGFR. In many organs like liver, lung, and kidneys

    Myofibroblast

    Myofibroblast

    Myofibroblast

  • Naive T cell
  • T cell which has not yet encountered its cognate antigen

    Chemokine receptor type 7 (CCR7); the absence of the activation markers CD25, CD44 or CD69; and the absence of memory CD45RO isoform. They also express functional

    Naive T cell

    Naive_T_cell

  • List of minor planets: 550001–551000
  • January 19, 2012 Haleakala Pan-STARRS 1  · 1.3 km MPC · JPL 550248 2012 CD44 — January 19, 2012 Kitt Peak Spacewatch H 470 m MPC · JPL 550249 2012 CZ45

    List of minor planets: 550001–551000

    List_of_minor_planets:_550001–551000

  • Sialyl-Lewis X
  • Chemical compound

    O-linked glycan attached to cell surface glycoproteins such as PSGL-1, CD43 or CD44. This sialyl-LewisX-mediated binding to selectins allows circulating leukocytes

    Sialyl-Lewis X

    Sialyl-Lewis X

    Sialyl-Lewis_X

  • Death receptor 4
  • Protein found in humans

    CD32 A B CD33 CD34 CD35 CD36 CD37 CD38 CD39 CD40 CD41 CD42 a b c d CD43 CD44 CD45 CD46 CD47 CD48 CD49 a b c d e f CD50 51–100 CD51 CD52 CD53 CD54 CD55

    Death receptor 4

    Death receptor 4

    Death_receptor_4

  • NKG2
  • Mammalian protein found in Homo sapiens

    CD32 A B CD33 CD34 CD35 CD36 CD37 CD38 CD39 CD40 CD41 CD42 a b c d CD43 CD44 CD45 CD46 CD47 CD48 CD49 a b c d e f CD50 51–100 CD51 CD52 CD53 CD54 CD55

    NKG2

    NKG2

  • Integrin alpha-1
  • Mammalian protein found in Homo sapiens

    CD32 A B CD33 CD34 CD35 CD36 CD37 CD38 CD39 CD40 CD41 CD42 a b c d CD43 CD44 CD45 CD46 CD47 CD48 CD49 a b c d e f CD50 51–100 CD51 CD52 CD53 CD54 CD55

    Integrin alpha-1

    Integrin alpha-1

    Integrin_alpha-1

  • Lupus
  • Autoimmune disease in which the immune system attacks healthy tissue

    isolated from whole blood of people with SLE show reduced expression of CD44 surface molecules involved in the uptake of apoptotic cells. Most of the

    Lupus

    Lupus

    Lupus

  • Angiopoietin-1 receptor
  • Protein-coding gene in the species Homo sapiens

    CD32 A B CD33 CD34 CD35 CD36 CD37 CD38 CD39 CD40 CD41 CD42 a b c d CD43 CD44 CD45 CD46 CD47 CD48 CD49 a b c d e f CD50 51–100 CD51 CD52 CD53 CD54 CD55

    Angiopoietin-1 receptor

    Angiopoietin-1 receptor

    Angiopoietin-1_receptor

  • LY9
  • Protein-coding gene in humans

    CD32 A B CD33 CD34 CD35 CD36 CD37 CD38 CD39 CD40 CD41 CD42 a b c d CD43 CD44 CD45 CD46 CD47 CD48 CD49 a b c d e f CD50 51–100 CD51 CD52 CD53 CD54 CD55

    LY9

    LY9

    LY9

  • Link domain
  • Protein domain

    cell-cell and cell-matrix interactions during inflammation and tumourigenesis; CD44 antigen, the main cell surface receptor for HA. Hyaladherin "Link domain

    Link domain

    Link domain

    Link_domain

  • List of modern Hangul characters in ISO/IEC 2022–compliant national character set standards
  • U+CD39 35-53 — 30-74 45-51 ᄎ+ᅪ+ᆼ 쵀 U+CD40 — 32-14 30-78 45-53 ᄎ+ᅫ+∅ 쵄 U+CD44 — — 30-79 — ᄎ+ᅫ+ᆫ 쵓 U+CD53 — 32-15 — — ᄎ+ᅫ+ᆺ 쵔 U+CD54 — 32-16 — — ᄎ+ᅫ+ᆻ 최

    List of modern Hangul characters in ISO/IEC 2022–compliant national character set standards

    List_of_modern_Hangul_characters_in_ISO/IEC_2022–compliant_national_character_set_standards

  • Gamma secretase
  • Type of protein

    membrane proteins, such as Notch, ErbB4, E-cadherin, N-cadherin, ephrin-B2, or CD44. The gamma secretase complex consists of four individual proteins: PSEN1

    Gamma secretase

    Gamma secretase

    Gamma_secretase

  • Inflammation
  • Physical effects resulting from activation of the immune system

    interstitium bind to extracellular matrix proteins via expressed integrins and CD44 to prevent them from leaving the site. A variety of molecules behave as chemoattractants

    Inflammation

    Inflammation

    Inflammation

  • CD99
  • Protein-coding gene in humans

    CD32 A B CD33 CD34 CD35 CD36 CD37 CD38 CD39 CD40 CD41 CD42 a b c d CD43 CD44 CD45 CD46 CD47 CD48 CD49 a b c d e f CD50 51–100 CD51 CD52 CD53 CD54 CD55

    CD99

    CD99

    CD99

  • Vocal cords
  • Folds of throat tissues that help to create n through vocalization

    but also of an optimal tissue stiffness that allows frequency control. CD44 is a cell surface receptor for HA. Cells such as fibroblasts are responsible

    Vocal cords

    Vocal cords

    Vocal_cords

  • LILRA2
  • Protein-coding gene in the species Homo sapiens

    CD32 A B CD33 CD34 CD35 CD36 CD37 CD38 CD39 CD40 CD41 CD42 a b c d CD43 CD44 CD45 CD46 CD47 CD48 CD49 a b c d e f CD50 51–100 CD51 CD52 CD53 CD54 CD55

    LILRA2

    LILRA2

    LILRA2

  • Epigenetics
  • Study of DNA modifications that do not change its sequence

    Sindikubwabo F, Cañeque T, Lafon A, Versini A, Lombard B, et al. (October 2020). "CD44 regulates epigenetic plasticity by mediating iron endocytosis". Nature Chemistry

    Epigenetics

    Epigenetics

    Epigenetics

  • CD146
  • Protein found in humans

    CD32 A B CD33 CD34 CD35 CD36 CD37 CD38 CD39 CD40 CD41 CD42 a b c d CD43 CD44 CD45 CD46 CD47 CD48 CD49 a b c d e f CD50 51–100 CD51 CD52 CD53 CD54 CD55

    CD146

    CD146

    CD146

  • Lymphopoiesis
  • Process which produces lymphocytes

    lineages (Lin) but expressing high levels of Sca1 and c-kit; HSC also express CD44, low levels of Thy1.1 (CD90), but no IL-7Ra or CD27.[citation needed] This

    Lymphopoiesis

    Lymphopoiesis

  • Tumor hypoxia
  • Situation where tumor cells have been deprived of oxygen

    hyaluronic acid CD44 pathway to target cancer and cancer metastasis has been investigated before; Almoustafa et al. demonstrated that targeting CD44 receptors

    Tumor hypoxia

    Tumor hypoxia

    Tumor_hypoxia

  • Thrombopoietin receptor
  • Protein-coding gene in the species Homo sapiens

    CD32 A B CD33 CD34 CD35 CD36 CD37 CD38 CD39 CD40 CD41 CD42 a b c d CD43 CD44 CD45 CD46 CD47 CD48 CD49 a b c d e f CD50 51–100 CD51 CD52 CD53 CD54 CD55

    Thrombopoietin receptor

    Thrombopoietin receptor

    Thrombopoietin_receptor

  • LILRA3
  • Protein-coding gene in the species Homo sapiens

    CD32 A B CD33 CD34 CD35 CD36 CD37 CD38 CD39 CD40 CD41 CD42 a b c d CD43 CD44 CD45 CD46 CD47 CD48 CD49 a b c d e f CD50 51–100 CD51 CD52 CD53 CD54 CD55

    LILRA3

    LILRA3

    LILRA3

  • Toll-like receptor 1
  • Cell surface receptor found in humans

    CD32 A B CD33 CD34 CD35 CD36 CD37 CD38 CD39 CD40 CD41 CD42 a b c d CD43 CD44 CD45 CD46 CD47 CD48 CD49 a b c d e f CD50 51–100 CD51 CD52 CD53 CD54 CD55

    Toll-like receptor 1

    Toll-like receptor 1

    Toll-like_receptor_1

  • Mucin
  • Glycoprotein

    Perlecan CS Chondroitin sulfate proteoglycans: Aggrecan Neurocan Brevican CD44 CSPG4 CSPG5 Platelet factor 4 Structural maintenance of chromosomes 3 KS

    Mucin

    Mucin

    Mucin

  • Proteoglycan
  • Class of compounds

    Perlecan CS Chondroitin sulfate proteoglycans: Aggrecan Neurocan Brevican CD44 CSPG4 CSPG5 Platelet factor 4 Structural maintenance of chromosomes 3 KS

    Proteoglycan

    Proteoglycan

    Proteoglycan

  • CD24
  • Mammalian protein found in humans

    Ringnér M, Saal LH, Gruvberger-Saal SK, Lövgren K, et al. (2008). "The CD44+/CD24- phenotype is enriched in basal-like breast tumors". Breast Cancer

    CD24

    CD24

    CD24

  • HYAL2
  • Protein-coding gene in the species Homo sapiens

    interactions between HYAL2 and proteins involved in the alternative splicing of CD44 pre-mRNA. Another study published in 2020, described roles for HYAL2 in the

    HYAL2

    HYAL2

    HYAL2

  • Basophil
  • Type of white blood cell

    that basophils may be defined as the cellular population positive for CD13, CD44, CD54, CD63, CD69, CD107a, CD123, CD164, CD193/ CCR3, CD203c, TLR-4, and

    Basophil

    Basophil

    Basophil

  • Toll-like receptor 10
  • Protein-coding gene in the species Homo sapiens

    CD32 A B CD33 CD34 CD35 CD36 CD37 CD38 CD39 CD40 CD41 CD42 a b c d CD43 CD44 CD45 CD46 CD47 CD48 CD49 a b c d e f CD50 51–100 CD51 CD52 CD53 CD54 CD55

    Toll-like receptor 10

    Toll-like receptor 10

    Toll-like_receptor_10

  • ICOSLG
  • Protein-coding gene in the species Homo sapiens

    CD32 A B CD33 CD34 CD35 CD36 CD37 CD38 CD39 CD40 CD41 CD42 a b c d CD43 CD44 CD45 CD46 CD47 CD48 CD49 a b c d e f CD50 51–100 CD51 CD52 CD53 CD54 CD55

    ICOSLG

    ICOSLG

    ICOSLG

  • KHDRBS1
  • Protein-coding gene in the species Homo sapiens

    promoting the inclusion of the variable exon 5 (v5) in CD44 correlating with cell migration potential. CD44 is a cell surface protein whose expression has been

    KHDRBS1

    KHDRBS1

    KHDRBS1

  • Breast cancer stem cell
  • Stem cells that may cause cancer

    key proteins have been deemed as markers for BCSCs: CD44, CD24 and aldehyde dehydrogenase (ALDH). CD44, a cell surface glycoprotein, plays a crucial role

    Breast cancer stem cell

    Breast_cancer_stem_cell

  • Uropod (immunology)
  • and chemotaxis. Uropod membranes generally have high density of CD43 and CD44 and adhesion receptors (ICAM-1, ICAM-3, B1 integrins, and ERM adaptor proteins)

    Uropod (immunology)

    Uropod_(immunology)

  • CXCR3
  • Protein-coding gene in humans

    CD32 A B CD33 CD34 CD35 CD36 CD37 CD38 CD39 CD40 CD41 CD42 a b c d CD43 CD44 CD45 CD46 CD47 CD48 CD49 a b c d e f CD50 51–100 CD51 CD52 CD53 CD54 CD55

    CXCR3

    CXCR3

    CXCR3

  • Crystallopathy
  • Disease caused by accumulation of crystals

    CLEC12A and NETosis). Crystals can attach to membranes via annexin II, CD44, and osteopontin. The most straightforward treatment of crystallopathies

    Crystallopathy

    Crystallopathy

  • Peptidoglycan
  • Polymer in bacterial cell walls

    Perlecan CS Chondroitin sulfate proteoglycans: Aggrecan Neurocan Brevican CD44 CSPG4 CSPG5 Platelet factor 4 Structural maintenance of chromosomes 3 KS

    Peptidoglycan

    Peptidoglycan

  • Interleukin 12 receptor, beta 1 subunit
  • Protein and coding gene in humans

    CD32 A B CD33 CD34 CD35 CD36 CD37 CD38 CD39 CD40 CD41 CD42 a b c d CD43 CD44 CD45 CD46 CD47 CD48 CD49 a b c d e f CD50 51–100 CD51 CD52 CD53 CD54 CD55

    Interleukin 12 receptor, beta 1 subunit

    Interleukin 12 receptor, beta 1 subunit

    Interleukin_12_receptor,_beta_1_subunit

  • LAIR1
  • Protein-coding gene in the species Homo sapiens

    CD32 A B CD33 CD34 CD35 CD36 CD37 CD38 CD39 CD40 CD41 CD42 a b c d CD43 CD44 CD45 CD46 CD47 CD48 CD49 a b c d e f CD50 51–100 CD51 CD52 CD53 CD54 CD55

    LAIR1

    LAIR1

    LAIR1

  • ATP1B3
  • Protein-coding gene in the species Homo sapiens

    CD32 A B CD33 CD34 CD35 CD36 CD37 CD38 CD39 CD40 CD41 CD42 a b c d CD43 CD44 CD45 CD46 CD47 CD48 CD49 a b c d e f CD50 51–100 CD51 CD52 CD53 CD54 CD55

    ATP1B3

    ATP1B3

    ATP1B3

  • CD320
  • Human gene

    CD32 A B CD33 CD34 CD35 CD36 CD37 CD38 CD39 CD40 CD41 CD42 a b c d CD43 CD44 CD45 CD46 CD47 CD48 CD49 a b c d e f CD50 51–100 CD51 CD52 CD53 CD54 CD55

    CD320

    CD320

    CD320

  • DHRS7B
  • Protein-coding gene in the species Homo sapiens

    disorder. In breast cancer cells expressing CD44 and CD24, DHRS7B expression was observed to be down regulated. CD44 is an antigen found on the surface of most

    DHRS7B

    DHRS7B

    DHRS7B

  • Moesin
  • Protein-coding gene in the species Homo sapiens

    positively charged amino acid cluster in the juxta-membrane cytoplasmic domain of CD44, CD43, and ICAM-2". J. Cell Biol. 140 (4): 885–95. doi:10.1083/jcb.140.4

    Moesin

    Moesin

    Moesin

  • Chondroitin sulfate proteoglycan
  • CSPG5 SMC3 (CSPG6, structural maintenance of chromosomes 3) Brevican (CSPG7) CD44 (CSPG8, cluster of differentiation 44) Phosphacan Neurocan, brevican, versican

    Chondroitin sulfate proteoglycan

    Chondroitin sulfate proteoglycan

    Chondroitin_sulfate_proteoglycan

  • Integrin alpha 3
  • Mammalian protein found in Homo sapiens

    CD32 A B CD33 CD34 CD35 CD36 CD37 CD38 CD39 CD40 CD41 CD42 a b c d CD43 CD44 CD45 CD46 CD47 CD48 CD49 a b c d e f CD50 51–100 CD51 CD52 CD53 CD54 CD55

    Integrin alpha 3

    Integrin alpha 3

    Integrin_alpha_3

  • Write-in candidate
  • Political term

    (November) 2012 5 SD3, SD9, SD33, AD15, AD31 0 36.0% 23.4% 13.2% 2014 16 CD23, CD44, BOE3, SD16, SD22, SD36, AD5, AD14, AD21, AD31, AD41, AD51, AD60, AD67, AD75

    Write-in candidate

    Write-in_candidate

  • Carcinoembryonic antigen
  • Biochemistry concept

    Alves CS, Konstantopoulos K (June 2008). "Carcinoembryonic antigen and CD44 variant isoforms cooperate to mediate colon carcinoma cell adhesion to E-

    Carcinoembryonic antigen

    Carcinoembryonic antigen

    Carcinoembryonic_antigen

  • Tyrosin-protein kinase Lck
  • Lymphocyte protein

    lymphoblastic leukemias. Lck has been shown to interact with: ADAM15, CD2, CD44, CD4, COUP-TFII, DLG1, NOTCH1, PIK3CA, PTPN6, PTPRC, UNC119, SYK, UBE3A,

    Tyrosin-protein kinase Lck

    Tyrosin-protein kinase Lck

    Tyrosin-protein_kinase_Lck

  • Intraepithelial lymphocyte
  • Found in the epithelial layer of mucosal linings

    undergo a post-thymic differentiation. These cells express activation markers (CD44, CD69) and unlike natural TCR+IELs express CD2, CD5, CD28, LFA-1, and Thy1

    Intraepithelial lymphocyte

    Intraepithelial lymphocyte

    Intraepithelial_lymphocyte

  • Glycoprotein
  • Protein with oligosaccharide modifications

    Perlecan CS Chondroitin sulfate proteoglycans: Aggrecan Neurocan Brevican CD44 CSPG4 CSPG5 Platelet factor 4 Structural maintenance of chromosomes 3 KS

    Glycoprotein

    Glycoprotein

    Glycoprotein

  • HAS2
  • Protein-coding gene in the species Homo sapiens

    addition, the interaction of hyaluronic acid with the leukocyte receptor CD44 is important in tissue-specific homing by leukocytes, and overexpression

    HAS2

    HAS2

    HAS2

  • Outline of immunology
  • Overview of and topical guide to immunology

    (MAdCAM-1) CD44 Carcinoembryonic antigens CEACAM1 CEACAM3 CEACAM4 CEACAM5 CEACAM6 CEACAM7 CEACAM8 CEACAM16 CEACAM18 CEACAM19 CEACAM20 CEACAM21 CD24 CD44 CD146

    Outline of immunology

    Outline_of_immunology

  • SMARCA4
  • Protein-coding gene in the species Homo sapiens

    bind BRCA1, as well as regulate the expression of the tumorigenic protein CD44. BRG1 works to activate or repress transcription. Having functional BRG1

    SMARCA4

    SMARCA4

    SMARCA4

  • Phillip Allen Sharp
  • American geneticist and molecular biologist

    031. PMID 16483934. Cheng C.; Sharp P.A. (January 2006). "Regulation of CD44 Alternative Splicing by SRm160 and its Potential Role in Tumor Cell Invasion"

    Phillip Allen Sharp

    Phillip Allen Sharp

    Phillip_Allen_Sharp

  • T. S. Wiley
  • PMID 9846203. Formby, Bent; T.S. Wiley (1999). "Bcl-2, survivin and variant CD44 v7-v10 are downregulated and p53 is upregulated in breast cancer cells by

    T. S. Wiley

    T._S._Wiley

  • Osteopontin
  • Mammalian protein found in Homo sapiens

    exact mechanisms of osteopontin signaling in PDAC are unknown, it binds to CD44 and integrins to trigger processes such as tumor progression and complement

    Osteopontin

    Osteopontin

    Osteopontin

  • Ironomycin
  • Chemical compound

    tumour cells (breast PDX), more efficiently that salinomycin and Docetaxel. CD44 mediating iron endocytosis prevails in the mesenchymal state of cancer cells

    Ironomycin

    Ironomycin

    Ironomycin

  • Dental follicle
  • Anatomical entity

    follicle cell cultures. Typical markers expressed within these cells include, CD44 and STRO1. Both Cell migration capacity and cell proliferation capacity of

    Dental follicle

    Dental follicle

    Dental_follicle

  • Lymphatic endothelium
  • Jones, Margaret; Jackson, David G. (1999). "LYVE-1, a new homologue of the CD44 glycoprotein, is a lymph-specific receptor for hyaluronan 1". The Journal

    Lymphatic endothelium

    Lymphatic_endothelium

  • MTDH
  • Protein-coding gene in the species Homo sapiens

    cells, MTDH has been shown to affect alternative splicing of genes such as CD44, which may also be associated with prostate cancer progression. LSF/TFCP2

    MTDH

    MTDH

    MTDH

  • Glycosaminoglycan
  • Polysaccharides found in animal tissue

    surface interactions involving hyaluronan are its well-known coupling with CD44, which may be related to tumor progression, and also with RHAMM (Hyaluronan-mediated

    Glycosaminoglycan

    Glycosaminoglycan

    Glycosaminoglycan

  • CD74
  • Mammalian protein found in humans

    chain can enhance stimulation of T cell responses through interaction with CD44". Cell. 74 (2): 257–268. doi:10.1016/0092-8674(93)90417-O. PMID 8343954.

    CD74

    CD74

    CD74

  • Macrophage migration inhibitory factor
  • Protein-coding gene in the species Homo sapiens

    MIF binds to CD74, inducing its phosphorylation and the recruitment of CD44 which then activates non-receptor tyrosine kinases, leading ultimately to

    Macrophage migration inhibitory factor

    Macrophage migration inhibitory factor

    Macrophage_migration_inhibitory_factor

  • Versican
  • Protein-coding gene in the species Homo sapiens

    P-selectin, and CD44 is also mediated by the interaction of CS chains of versican with the carbohydrate-binding domain of these molecules. Both CD44 and L-selectin

    Versican

    Versican

    Versican

  • Hyaluronan synthase
  • Class of enzymes

    from the primary tumor mass and if HA associates with receptors such as CD44, the activation of Rho GTPases can promote EMT of the cancer cells. During

    Hyaluronan synthase

    Hyaluronan synthase

    Hyaluronan_synthase

  • EMP3
  • Protein-coding gene in the species Homo sapiens

    progression correlated with glioblastoma (GBM). Reduction in EMP3 expression in CD44-high GBM cell lines promotes apoptosis of the cancer cell lines and disables

    EMP3

    EMP3

    EMP3

  • CD43
  • Mammalian protein found in humans

    positively charged amino acid cluster in the juxta-membrane cytoplasmic domain of CD44, CD43, and ICAM-2". J. Cell Biol. 140 (4): 885–95. doi:10.1083/jcb.140.4

    CD43

    CD43

    CD43

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