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Chemical compound
2-Thiouracil is a chemical derivative of uracil in which the oxygen atom in the 2-position of the ring is substituted by sulfur. It is classified as a
2-Thiouracil
Index of chemical compounds with the same name
Thiouracil may refer to: 2-Thiouracil 4-Thiouracil This set index article lists chemical compounds articles associated with the same name. If an internal
Thiouracil
Beta blocker drug
beta blockers at usual doses carry an unacceptable risk of provoking type 2 diabetes. Propranolol is not recommended for the treatment of high blood pressure
Propranolol
Enzyme expressed mainly in the thyroid gland
Hidaka H (Jul 1976). "Effect of antithyroid agents 6-propyl-2-thiouracil and 1-methyl-2-mercaptoimidazole on human thyroid iodine peroxidase". The Journal
Thyroid_peroxidase
Thyroid hormone medication
Constitution and Synthesis of Desiodo-Thyroxine". The Biochemical Journal. 20 (2): 300–313. doi:10.1042/bj0200300. PMC 1251714. PMID 16743659. DrugBank DB00451
Levothyroxine
Chemical compound
triiodothyronine (T3). These compounds inhibit 5'deiodinase (5'DID-1 and 5'DID-2) enzymes, which catalyse T4-T3 conversion in the thyroid cell, liver, kidney
Iopanoic_acid
Chemical compound
treat a patient with the condition. He later published evidence that thiouracil was more effective and began a search for analogues with higher potency
Thiamazole
Chemical element with atomic number 34 (Se)
known isotopes. Selenium compounds commonly exist in the oxidation states −2, +2, +4, and +6. It is a nonmetal (more rarely considered a metalloid) with
Selenium
Chemical compound
Institutes of Health. 14 March 2024. Archived from the original on 2 April 2024. Retrieved 2 April 2024. "Rezdiffra EPAR". ema.europa.eu. European Medicines
Resmetirom
Index of chemical compounds with the same molecular formula
(molar mass: 128.15 g/mol, exact mass: 128.0044 u) may refer to: 2-Thiouracil 4-Thiouracil This set index page lists chemical structure articles associated
C4H4N2OS
Organosulfur compounds with an >NC(=S)N< structure
with the formula S=C(NR2)2 and structure R2N−C(=S)−NR2. The parent member of this class of compounds is thiourea (S=C(NH2)2). Substituted thioureas are
Thioureas
Isotope of iodine
(which is soon reduced to iodide). 131I is a fission product with a yield of 2.878% from uranium-235, and can be released in nuclear weapons tests and nuclear
Iodine-131
Chemical element with atomic number 53 (I)
purification the iodine is packed. 2 HI + Cl2 → I2↑ + 2 HCl I2 + 2 H2O + SO2 → 2 HI + H2SO4 2 HI + Cl2 → I2↓ + 2 HCl These sources ensure that Chile
Iodine
Class of organic compounds
characteristally hydrolyze to give the amide: RC(S)NH2 + H2O + Hg(O2CCH3)2 → RC(O)NH2 + 2 HO2CCH3 + HgS In qualitative inorganic analysis, thioacetamide is in
Thioamide
Hormones produced by the thyroid gland
triiodothyronine, or both. It is a common disorder that affects approximately 2% of women and 0.2% of men. Thyrotoxicosis is often used interchangeably with hyperthyroidism
Thyroid_hormones
future hold?". Indian Journal of Endocrinology and Metabolism. 16 (Suppl 2): S159–S161. doi:10.4103/2230-8210.104029. ISSN 2230-8210. PMC 3603016. PMID 23565368
Thyromimetic
Chemical compound
(March 2012). "Thyroid emergencies". The Medical Clinics of North America. 96 (2): 385–403. doi:10.1016/j.mcna.2012.01.015. PMID 22443982. Altshuler LL, Bauer
Liothyronine
Medication used to treat hyperthyroidism
chemotherapy; antithyroid compounds; synthesis of 5- and 6-substituted 2-thiouracils from beta-oxoesters and thiourea". Journal of the American Chemical
Propylthiouracil
Chemical compound
Carbimazole Genistein Methimazole Methylthiouracil Propylthiouracil 2-Thiouracil Thiourea DIOTooltip Iodothyronine deiodinase Inhibitors: Dexpropranolol
Liotrix
Medication used for hyperthyroidism
Carbimazole Genistein Methimazole Methylthiouracil Propylthiouracil 2-Thiouracil Thiourea DIOTooltip Iodothyronine deiodinase Inhibitors: Dexpropranolol
Carbimazole
Chemical compound
Thioharnstoff und Acetessigäther". Justus Liebigs Annalen der Chemie. 236 (1–2): 1–32. doi:10.1002/jlac.18862360102. Vorbrüggen H, Ruh-Pohlenz C (April 2004)
Methylthiouracil
Amino acid
nomenclature possible?". Biochemical Education. 26 (2): 116–118. doi:10.1016/S0307-4412(97)00167-2. Hunter T (2012-09-19). "Why nature chose phosphate
Tyrosine
Type of cellular receptor that facilitates taste
Common bitter ligands include cycloheximide, denatonium, PROP (6-n-propyl-2-thiouracil), PTC (phenylthiocarbamide), and β-glucopyranosides. Signal transduction
Taste_receptor
Classification of agents that are possibly carcinogenic to humans
Tetrachlorvinphos Tetrahydrofuran Tetranitromethane Thioacetamide 4,4'-Thiodianiline 2-Thiouracil Titanium dioxide Toluene diisocyanates Toxaphene (Polychlorinated camphenes)
IARC_group_2B
Chemical compound
development of resmetirom (MGL-3196)". Expert Opinion on Investigational Drugs. 29 (2): 99–101. doi:10.1080/13543784.2020.1708899. ISSN 1354-3784. PMID 31868036
VK2809
Chemical compound
Carbimazole Genistein Methimazole Methylthiouracil Propylthiouracil 2-Thiouracil Thiourea DIOTooltip Iodothyronine deiodinase Inhibitors: Dexpropranolol
Ipodate_sodium
Chemical compound
cardiometabolic patients: a double-blind randomized controlled trial". PLOS ONE. 9 (2) e86890. Bibcode:2014PLoSO...986890V. doi:10.1371/journal.pone.0086890. PMC 3931609
Omzotirome
Ion, and compounds containing the ion
quaternary ammonium cations or other ions, for example, nitronium cation (NO+2). The term perchlorate can also describe perchlorate esters or covalent perchlorates
Perchlorate
Mammalian protein found in Homo sapiens
"Iodine metabolism and thyroid physiology: current concepts". Thyroid. 7 (2): 177–181. doi:10.1089/thy.1997.7.177. PMID 9133680. Chen I, Lui F (2022)
Sodium/iodide_cotransporter
Chemical compound
Carbimazole Genistein Methimazole Methylthiouracil Propylthiouracil 2-Thiouracil Thiourea DIOTooltip Iodothyronine deiodinase Inhibitors: Dexpropranolol
Dextrothyroxine
Organosulfur compound (S=C(NH2)2)
2-dibromoethane: C2H4Br2 + 2 SC(NH2)2 → [C2H4(SC(NH2)2)2]Br2 [C2H4(SC(NH2)2)2]Br2 + 2 KOH → C2H4(SH)2 + 2 OC(NH2)2 + 2 KBr Like other thioamides, thiourea
Thiourea
Chemical compound
T3 is about 2.5 days. The half-life of T4 is about 6.5 days. T3 levels start to rise 45 minutes after administration and peak at about 2.5 hours. Although
Triiodothyronine
Chemical compound
a blood-red solution forms mainly due to the formation of [Fe(NCS)(H2O)5]2+, i.e. pentaaqua(thiocyanato-N)iron(III). Lesser amounts of other hydrated
Thiocyanate
Thiocyanates". In Saul Patai (ed.). Cyanates and Their Thio Derivatives: Part 2, Volume 2. PATAI'S Chemistry of Functional Groups. pp. 619–818. doi:10.1002/9780470771532
Organic_thiocyanates
Chemical compound
cases and a review of the literature". Israel Journal of Medical Sciences. 2 (4): 453–6. PMID 4290684. Woenckhaus, U.; Girlich, C. (2005). "Therapie und
Potassium_perchlorate
Chemical compound
to give the isoflavone. The enzymes involved are isoflavonoid synthase and 2-hydroxyisoflavanone dehydratase. naringenin Synthase 2,4',5,7-
Genistein
Chemical compound
4-Thiouracil is a heterocyclic organic compound having a pyrimidine skeleton. It is a derivative of the nucleobase uracil with a sulfur instead of oxygen
4-Thiouracil
Pharmaceutical compound
development by Autobahn Therapeutics. As of December 2025, it is in phase 2 clinical trials for treatment of major depressive disorder and bipolar depression
Elunetirom
Chemical compound
Carbimazole Genistein Methimazole Methylthiouracil Propylthiouracil 2-Thiouracil Thiourea DIOTooltip Iodothyronine deiodinase Inhibitors: Dexpropranolol
Benzylthiouracil
Chemical compound
issues warning on products containing Tiratricol (TRIAC)" (Press release). Health Canada. 2 December 1999. Retrieved 8 August 2007. Portal: Medicine
Tiratricol
Mammalian protein found in Homo sapiens
The Journal of Clinical Endocrinology and Metabolism. 73 (2): 262–267. doi:10.1210/jcem-73-2-262. PMID 1906892. Li P, Janssen OE, Takeda K, Bertenshaw
Thyroxine-binding_globulin
Chemical compound
Carbimazole Genistein Methimazole Methylthiouracil Propylthiouracil 2-Thiouracil Thiourea DIOTooltip Iodothyronine deiodinase Inhibitors: Dexpropranolol
TERN-501
Chemical compound
and questions about the future". Expert Opinion on Therapeutic Targets. 20 (2): 145–149. doi:10.1517/14728222.2016.1090429. ISSN 1744-7631. PMID 26565124
Sobetirome
Serum protein related to amyloid diseases
a new transthyretin (prealbumin) variant". Br Heart J. 70 (2): 111–5. doi:10.1136/hrt.70.2.111. PMC 1025267. PMID 8038017. Blanco-Jerez CR, Jiménez-Escrig
Transthyretin
Chemical compound
compounds and dietary habits. Much of this work has focused on 6-propyl-2-thiouracil (PROP), a compound related to PTC that has lower toxicity. A supertaster
Phenylthiocarbamide
Protein produced and used by the thyroid
PMC 9254275. PMID 35544053. Rousset BL, Dupuy C, Miot F, Dumont J (2000). "Chapter 2 Thyroid Hormone Synthesis and Secretion". In Feingold KR, Anawalt B, Boyce
Thyroglobulin
Thyroid gland prepared for medical use
thyroid B.P.?". Lancet. 1 (7172): 329–332. doi:10.1016/s0140-6736(61)91498-2. PMID 13764789. Catz B, Ginsburg E, Salenger S (January 1962). "Clinically
Desiccated_thyroid_extract
Pharmaceutical drug
Cheng, Long; Huang, Yidan; Rao, Wanglin; Shi, Honglu; Li, Jingya (October 2, 2024). "Potential therapeutic strategies for MASH: from preclinical to clinical
ASC41
Nuclear protein
corepressor proteins such as nuclear receptor co-repressor 1 (N-CoR) and 2 (N-CoR2). While these cofactors are present, TR binds HREs in a transcriptionally
Thyroid_hormone_receptor
Protein-coding gene in the species Homo sapiens
Cheong JH, Lee YC, Meltzer PS, Lee JW (Nov 1999). "A nuclear factor, ASC-2, as a cancer-amplified transcriptional coactivator essential for ligand-dependent
Thyroid hormone receptor alpha
Thyroid_hormone_receptor_alpha
Class of enzymes
insertion sequence (SECIS), be present to bind with SECIS binding protein-2 (SBP-2), which binds with elongation factor EFsec. The translation of selenocysteine
Iodothyronine_deiodinase
Protein-coding gene in the species Homo sapiens
beta (TR-beta) also known as nuclear receptor subfamily 1, group A, member 2 (NR1A2), is a nuclear receptor protein that in humans is encoded by the THRB
Thyroid_hormone_receptor_beta
Chemical compound or ion
electrode potential for TcO− 4/TcO 2 is only +0.738 V in acidic solution, as compared to +1.695 V for MnO− 4/MnO 2. Because of its diminished oxidizing
Pertechnetate
Hormone antagonist acting upon thyroid hormones
reaction which generally resolves on cessation of drug. It occurs in about 0.2 to 0.3% of cases treated with antithyroid drugs. Other side effects include
Antithyroid_agent
Chemical compound
future hold?". Indian Journal of Endocrinology and Metabolism. 16 (Suppl 2): S159–S161. doi:10.4103/2230-8210.104029. ISSN 2230-8210. PMC 3603016. PMID 23565368
Eprotirome
Chemicals regulated in the United States
Thiodicarb 59669-26-0 Thioguanine 154-42-7 Thiophanate methyl 23564-05-8 2-Thiouracil 141-90-2 Thiourea 62-56-6 Thorium dioxide 1314-20-1 Tobacco, oral use of
California Proposition 65 list of chemicals
California_Proposition_65_list_of_chemicals
Chemical compound of RNA
acid: C4H4O4 + NH2CONH2 → C4H4N2O2 + 2 H2O + CO Uracil can also be synthesized by a double decomposition of thiouracil in aqueous chloroacetic acid. Photodehydrogenation
Uracil
Chemical compound
disproportionation processes: TcO 4 − + e − ⟶ TcO 4 2 − 2 TcO 4 2 − ⟶ TcO 4 − + Tc V 2 Tc V ⟶ TcO 4 2 − + Tc IV Tc V + TcO 4 2 − ⟶ Tc IV + TcO 4 − {\displaystyle {\begin{array}{l}{\ce
Sodium_pertechnetate
Chemical compound
are active site (binding site for 1-ethoxymethyl-5-ethyl-6-phenylthio-2-thiouracil) and Foscarnet (also known as phosphonoformic acid) binding site of the
Calanolide_A
Endocrine gland in the neck
throughout the mid twentieth century, including the use of radioactive iodine, thiouracil and fine needle aspiration. Either Aetius in the sixth century CE or Persian
Thyroid
Chemical compound
4-Thiouridine is an atypical nucleoside formed with the 4-thiouracil base found in transfer RNA (tRNA). Its biosynthesis has been determined. The IUPAC
4-Thiouridine
Inflammation of the parotid glands
neoplastic processes. Rarely, drugs such as iodides, phenylbutazone, thiouracil, isoproterenol, heavy metals, sulfisoxazole, and phenothiazines cause
Parotitis
for fluorescent labeling occurred in 1971 with a 4-thiouridine and 4-thiouracil. This research along with others, which included various types of direct
Aminoallyl_nucleotide
Chemical compound
estrogens. In addition, amphenone B inhibits the production of thyroxine by a thiouracil-like mechanism, specifically via inhibition of organic binding of iodine
Amphenone_B
reflex inhibitory fibers" "Treatment of thyrotoxicosis with thiourea and thiouracil" "Demonstrated that soil bacteria can destroy pathogenic bacteria" "Work
List of nominees for the Nobel Prize in Physiology or Medicine (1940–1949)
List_of_nominees_for_the_Nobel_Prize_in_Physiology_or_Medicine_(1940–1949)
DNA structure
invasion through the simultaneous formation of diaminopurine (D) and thiouracil (Us) which substitute for adenine and thymine, respectively. The pc PNA
Triple-stranded_DNA
English doctor
Grainger A, Gregson DA, Pemberton HS. Thiouracil in the Treatment of Thyrotoxicosis. British Medical Journal. 1945 Sep 15; 2(4419):343–345. Pemberton HS. Sign
Hugh_Pemberton_(physician)
American physician
Bissell, Grosvenor W.; Peters, Jean B. (1944). "Anatomical Effects of Thiouracil". Endocrinology. 34 (5): 317–328. doi:10.1210/endo-34-5-317. Lloyd, Charles
Robert_Hardin_Williams
Photochemical technique
photodissociation spectroscopy of iodide ion–thiouracil clusters". Physical Chemistry Chemical Physics. 23 (2): 1021–1030. Bibcode:2021PCCP...23.1021U. doi:10
Photochemical_action_plots
MeSH D03.383.742.698.875.700 – pentoxyl MeSH D03.383.742.698.875.842 – thiouracil MeSH D03.383.742.698.875.842.455 – methylthiouracil MeSH D03.383.742.698
List_of_MeSH_codes_(D03)
2 THIOURACIL
2 THIOURACIL
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2 THIOURACIL
2 THIOURACIL
2 THIOURACIL
2 THIOURACIL
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