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WNT11

  • WNT11
  • Protein-coding gene in the species Homo sapiens

    Protein Wnt-11 is a protein that in humans is encoded by the WNT11 gene. The WNT gene family consists of structurally related genes that encode secreted

    WNT11

    WNT11

    WNT11

  • Wnt signaling pathway
  • Group of signal transduction pathways involved in embryonic development

    WNT5B, WNT6, WNT7A, WNT7B, WNT8A, WNT8B, WNT9A, WNT9B, WNT10A, WNT10B, WNT11, WNT16 Mus musculus (Identical proteins as in H. sapiens) Wnt1, Wnt2, Wnt2B

    Wnt signaling pathway

    Wnt_signaling_pathway

  • Carl-Philipp Heisenberg
  • German biologist

    Derek L.; Smith, James C.; Wilson, Stephen W. (May 2000). "Silberblick/Wnt11 mediates convergent extension movements during zebrafish gastrulation".

    Carl-Philipp Heisenberg

    Carl-Philipp_Heisenberg

  • Xenopus
  • Genus of amphibians

    specification and morphogenesis by antagonizing both canonical and noncanonical Wnt11 signaling". Genes & Development. 22 (21): 3050–3063. doi:10.1101/gad.1687308

    Xenopus

    Xenopus

    Xenopus

  • Protein Wnt-9B
  • Protein-coding gene in the species Homo sapiens

    of the Wolffian duct in early male and female embryos. In the embryos, Wnt11 is expressed at the branching points of the kidney tubules while WNT9B is

    Protein Wnt-9B

    Protein Wnt-9B

    Protein_Wnt-9B

  • Symmetry breaking and cortical rotation
  • microtubules, which transport the maternal dorsalizing factors, such as wnt11 mRNA, wnt5a mRNA, and Dishevelled protein. A series of experiments utilizing

    Symmetry breaking and cortical rotation

    Symmetry_breaking_and_cortical_rotation

  • Retinal precursor cells
  • Type of cell in the human eye

    suggested to play a role in precursor cell maintenance. In contrast to Fz4, Wnt11 is localized in the center of the developing retina and is suggested to

    Retinal precursor cells

    Retinal precursor cells

    Retinal_precursor_cells

  • Paneth cell
  • Anti-microbial epithelial cell of the small intestine

    cell renewal. They express the canonical Wnt ligands: Wnt3a, Wnt9b, and Wnt11, which bind to Frizzled receptors on intestinal stem cells to drive β-catenin/Tcf

    Paneth cell

    Paneth cell

    Paneth_cell

  • SMAD3
  • Protein-coding gene in humans

    the developmental genes regulated by this pathway include FGF1, NGF, and WNT11 as well as stem/progenitor cell associated genes CD34 and CXCR4. The activity

    SMAD3

    SMAD3

    SMAD3

  • Jeff Wrana
  • Cancer researcher

    protein in cancer-associated fibroblasts induced exosomal trafficking of Wnt11 to cancer cells, promoting metastasis through induction of the core planar

    Jeff Wrana

    Jeff_Wrana

  • SPRY2
  • Protein-coding gene in the species Homo sapiens

    proteins regulate ureteric branching by coordinating reciprocal epithelial Wnt11, mesenchymal Gdnf and stromal Fgf7 signalling during kidney development"

    SPRY2

    SPRY2

    SPRY2

  • List of human protein-coding genes 9
  • O14905 18356 WNT10A HGNC:13829; Q9GZT5 18357 WNT10B HGNC:12775; O00744 18358 WNT11 HGNC:12776; O96014 18359 WNT16 HGNC:16267; Q9UBV4 18360 WRAP53 HGNC:25522;

    List of human protein-coding genes 9

    List_of_human_protein-coding_genes_9

  • Jim Cuthbert Smith
  • British scientist (born 1954)

    Stemple, Derek L.; Smith, James C.; Wilson, Stephen W. (2000). "Silberblick/Wnt11 mediates convergent extension movements during zebrafish gastrulation".

    Jim Cuthbert Smith

    Jim Cuthbert Smith

    Jim_Cuthbert_Smith

  • Embryoid body
  • Three-dimensional aggregate of pluripotent stem cells

    regulates embryonic stem cell fate via differential expression of WNT5a and WNT11". Proceedings of the National Academy of Sciences. 106 (40): 16978–16983

    Embryoid body

    Embryoid body

    Embryoid_body

  • Gremlin (protein)
  • Inhibitor protein in the TGF beta signaling pathway

    "Reduction of BMP4 activity by gremlin 1 enables ureteric bud outgrowth and GDNF/WNT11 feedback signalling during kidney branching morphogenesis". Development

    Gremlin (protein)

    Gremlin_(protein)

  • Makoto Furutani-Seiki
  • Japanese molecular biologist

    Takahiro; Kitagawa, Daiju; Kondoh, Hisato (2010-07-01). "Negative regulation of wnt11 expression by Jnk signaling during zebrafish gastrulation". Journal of Cellular

    Makoto Furutani-Seiki

    Makoto_Furutani-Seiki

  • Regional differentiation
  • Identification of different areas of development in an early embryo

    Birsoy B, Yan D, Asashima M, Wylie C, Lin X, Heasman J (2005). "Maternal wnt11 activates the canonical wnt signaling pathway required for axis formation

    Regional differentiation

    Regional_differentiation

  • EVI5L
  • Protein-coding gene in the species Homo sapiens

    required for cardiac progenitor cell differentiation and positively-regulates Wnt11/AP-1 signalling in zebrafish". Cilia. 1 (Suppl 1) O6. doi:10.1186/2046-2530-1-S1-O6

    EVI5L

    EVI5L

    EVI5L

  • Immune system contribution to regeneration
  • tissue repair and remodeling. Key ligands expressed by macrophages Wnt5a and Wnt11 enhance the expression of the VEGF inhibitory receptor Flt1 so that blocking

    Immune system contribution to regeneration

    Immune_system_contribution_to_regeneration

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