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Protein-coding gene in the species Homo sapiens
WD repeat-containing protein 11 (WDR11) also known as bromodomain and WD repeat-containing protein 2 (BRWD2) is a protein that in humans is encoded by
WD repeat-containing protein 11
WD_repeat-containing_protein_11
Protein-coding gene in humans
WD repeat and coiled coil containing protein (WDCP) is a protein which in humans is encoded by the WDCP gene. The function of the protein is not completely
WD repeat and coiled coil containing protein
WD_repeat_and_coiled_coil_containing_protein
Protein-coding gene in humans
Bromodomain and WD repeat-containing protein 3 is a protein that in humans is encoded by the BRWD3 gene. The protein encoded by this gene contains a bromodomain
Bromodomain and WD repeat-containing protein 3
Bromodomain_and_WD_repeat-containing_protein_3
Protein-coding gene in the species Homo sapiens
Methylosome protein 50 is a protein that in humans is encoded by the WDR77 gene. WD repeat-containing protein 77 has been shown to interact with CTDP1
WD repeat-containing protein 77
WD_repeat-containing_protein_77
Protein-coding gene in the species Homo sapiens
WD repeat containing planar cell polarity effector is a protein that in humans is encoded by the WDPCP gene. This gene encodes a cytoplasmic WD40 repeat
WD repeat containing planar cell polarity effector
WD_repeat_containing_planar_cell_polarity_effector
Protein-coding gene in the species Homo sapiens
F-box/WD repeat-containing protein 1A (FBXW1A) also known as βTrCP1 or Fbxw1 or hsSlimb or pIkappaBalpha-E3 receptor subunit is a protein that in humans
F-box/WD repeat-containing protein 1A
F-box/WD_repeat-containing_protein_1A
Protein-coding gene in the species Homo sapiens
WD repeat-containing protein 3 is a protein that in humans is encoded by the WDR3 gene. This gene encodes a nuclear protein containing 10 WD repeats. WD
WDR3
Topics referred to by the same term
chick development WD repeat-containing protein 11 (HH14) Search for "hh14" or "hh-14" on Wikipedia. All pages with titles containing HH-14 All pages with
HH14
Protein-coding gene in the species Danio rerio
11 also known as WD Repeat Domain 23 (WDR23) is a protein that in humans is encoded by the DCAF11 gene. DCAF11 is a WD40 repeat protein, containing seven
DCAF11
Protein family
A leucine-rich repeat (LRR) is a protein structural motif that forms an α/β horseshoe fold. It is composed of repeating 20–30 amino acid stretches that
Leucine-rich_repeat
Protein-coding gene in humans
CCDC120 contains a 120bp repeat near the 3' end. CCDC120 has 3 identifiable paralogs in humans, FERM Domain Containing 4A, FERM domain Containing 4B, and
Coiled-coil domain containing protein 120
Coiled-coil_domain_containing_protein_120
Protein-coding gene in the species Homo sapiens
WD repeat-containing protein 46 also known as WD repeat-containing protein BING4 is a protein that in humans is encoded by the WDR46 gene. The name is
WDR46
Protein-coding gene in the species Homo sapiens
WD repeat-containing protein 1 is a protein that in humans is encoded by the WDR1 gene. This gene encodes a protein containing 9 WD repeats. WD repeats
WDR1
WD repeat and FYVE domain-containing protein 3 (WDFY3), also known as Autophagy-linked FYVE protein (ALFY), is a large protein encoded by the WDFY3 gene
WDFY3
Protein-coding gene in the species Homo sapiens
WD repeat-containing protein 24 is a protein that in humans is encoded by the WDR24 gene. GRCh38: Ensembl release 89: ENSG00000127580 – Ensembl, May 2017
WDR24
Protein-coding gene in the species Homo sapiens
WD repeat domain phosphoinositide-interacting protein 3 (WIPI-3), also known as WD repeat-containing protein 45-like is a protein that in humans is encoded
WDR45L
WD40-repeat-containing protein
F-box-like/WD repeat-containing protein TBL1XR1 is a protein that in humans is encoded by the TBL1XR1 gene. The protein encoded by this gene has sequence
TBL1XR1
Protein-coding gene in the species Homo sapiens
G-protein beta-subunit-like polypeptide which is a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino
GNB1L
Protein-coding gene in the species Homo sapiens
WD repeat-containing protein 62 is a protein that in humans is encoded by the WDR62 gene. WDR62 is a scaffold protein and interacts with different kinases
WDR62
Protein-coding gene in the species Homo sapiens
WD repeat domain 57 (U5 snRNP specific), also known as WDR57, is a gene found in many organisms, including, but not limited to Homo sapiens, Gallus gallus
WDR57
Human gene
WDR88 (WD repeat containing protein 88) is a protein, which in humans, is encoded by the gene WDR88. It consists of seven WD40 repeats, which form a seven-bladed
WDR88
Protein-coding gene in the species Homo sapiens
The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different
KDM2A
Protein-coding gene in the species Homo sapiens
WD repeat domain phosphoinositide-interacting protein 1 (WIPI-1), also known as Atg18 protein homolog (ATG18) and WD40 repeat protein interacting with
WIPI1
Protein-coding gene in the species Homo sapiens
The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different
FBXO11
Protein-coding gene in the species Homo sapiens
NACHT and WD repeat domain containing 1, is a gene found in vertebrates, which encodes a protein that contains a NACHT domain and a WD40 repeat domain.
NWD1
Protein-coding gene in the species Homo sapiens
F-box/WD repeat-containing protein 10 is a protein that in humans is encoded by the FBXW10 gene. Members of the F-box protein family, such as FBXW10,
FBXW10
Protein-coding gene in the species Homo sapiens
Glutamate-rich WD repeat-containing protein 1 is a WD40 repeat protein (containing five WD40 repeat motifs) that in humans is encoded by the GRWD1 gene
GRWD1
Protein-coding gene in the species Homo sapiens
Intraflagellar transport protein 80 homolog (IFT80), also known as WD repeat-containing protein 56, is a protein that in humans is encoded by the IFT80
IFT80
Protein-coding gene in the species Homo sapiens
Dreyfuss G (Feb 2002). "Gemin5, a novel WD repeat protein component of the SMN complex that binds Sm proteins". J Biol Chem. 277 (7): 5631–6. doi:10.1074/jbc
Gem-associated_protein_5
Protein-coding gene in the species Homo sapiens
The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different
FBXO24
Protein-coding gene in the species Homo sapiens
F-box/WD repeat-containing protein 2 is a protein that in humans is encoded by the FBXW2 gene. F-box proteins are an expanding family of eukaryotic proteins
FBXW2
Protein-coding gene in the species Homo sapiens
Dystrophia myotonica WD repeat-containing protein is a protein that in humans is encoded by the DMWD gene. GRCh38: Ensembl release 89: ENSG00000185800
DMWD_(gene)
Human chromosome
WBP1: WW domain-binding protein 1 WDCP: WD Repeat and Coiled Coil Containing Protein WDPCP: encoding protein Wd repeat containing planar cell polarity effector
Chromosome_2
Protein-coding gene in the species Homo sapiens
WD repeat and SOCS box-containing protein 1 is a protein that in humans is encoded by the WSB1 gene. This gene encodes a member of the WD-protein subfamily
WSB1
Protein-coding gene in the species Homo sapiens
WD repeat-containing protein 26 is a protein that in humans is encoded by the WDR26 gene. This gene encodes a member of the WD repeat protein family.
WDR26
Protein-coding gene in the species Homo sapiens
WD repeat-containing protein 68 is a protein that in humans is encoded by the DCAF7 gene. WDR68 has been shown to interact with DYRK1A. GRCm38: Ensembl
WDR68
Human chromosome
protein BACH1 BRWD1: encoding bromodomain and WD repeat-containing protein 1 BTG3: encoding protein BTG3 C21orf58: encoding uncharacterized protein C21orf58
Chromosome_21
Pathogenic type of misfolded protein
Murdoch H, Dennis MJ, Hall GA, Bott R, Crabb WD, et al. (May 2009). "Decontamination of prion protein (BSE301V) using a genetically engineered protease"
Prion
Protein-coding gene in the species Homo sapiens
The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different
FBXL5
Protein kinase found in humans
The LRRK2 gene encodes a protein with an armadillo repeats (ARM) region, an ankyrin repeat (ANK) region, a leucine-rich repeat (LRR) domain, a kinase domain
LRRK2
Protein-coding gene in the species Homo sapiens
A, Paushkin S, et al. (Mar 2002). "A novel WD repeat protein component of the methylosome binds Sm proteins". J. Biol. Chem. 277 (10): 8243–7. doi:10.1074/jbc
Protein arginine methyltransferase 5
Protein_arginine_methyltransferase_5
Protein-coding gene in the species Homo sapiens
The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different
FBXO6
Protein-coding gene in the species Homo sapiens
WD repeat-containing protein 44 is a protein that in humans is encoded by the WDR44 gene. GRCh38: Ensembl release 89: ENSG00000131725 – Ensembl, May 2017
WDR44
Protein-coding gene in the species Homo sapiens
exons. WDR12 is a member of the WD repeat WDR12/YTM1 family and contains 7 WD repeats. Each WD repeat typically contains a C-terminal tryptophan-aspartic
WDR12
Investigational Parkinson's disease drugs
(AKST-6021) – plasma protein fraction and neurogenesis stimulant [34] ION-859 (BIIB-094; ION859; IONIS-BIIB7Rx) – leucine-rich repeat kinase 2 (LRRK2) inhibitor
List of investigational Parkinson's disease drugs
List_of_investigational_Parkinson's_disease_drugs
Human chromosome
TTC28: encoding protein tetratricopeptide repeat domain 28 TTLL1: encoding enzyme probable tubulin polyglutamylase TTLL1 XRCC6: encoding protein Ku70 The following
Chromosome_22
the X chromosome in Drosophila and encodes for the relatively large WD-repeat protein, rabconnectin-3A. Rabconnectin-3A is involved in Notch signalling
Rabconnectin-3A
Human chromosome
encoding protein Tectonin beta-propeller repeat containing 1 TMED4: transmembrane emp24 domain-containing protein 4 TMEM130: transmembrane protein 130 TMEM196
Chromosome_7
Protein-coding gene in the species Homo sapiens
WD40 repeat-containing protein SMU1 is a protein that in humans is encoded by the SMU1 gene. GRCh38: Ensembl release 89: ENSG00000122692 – Ensembl, May
SMU1
Protein-coding gene in the species Homo sapiens
WD repeat domain phosphoinositide-interacting protein 2 is a protein that in humans is encoded by the WIPI2 gene. WD40 repeat proteins are key components
WIPI2
Members of the coronin family, such as CORO1B, are WD repeat-containing actin-binding proteins that regulate cell motility. A mammalian coronin enriches
CORO1B
Protein-coding gene in the species Homo sapiens
The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different
FBXO2
Toroid protein structure formed from beta sheets
Nambudripad R, Smith TF (September 1994). "The ancient regulatory-protein family of WD-repeat proteins". Nature. 371 (6495): 297–300. Bibcode:1994Natur.371..297N
Beta-propeller
Rare genetic disorder
avolition. The WDR26 gene provides instructions for making the WD repeat-containing protein 26 (WDR26), which is produced by most human cells. One of WDR26's
Skraban–Deardorff_syndrome
Human chromosome
synthase-interacting protein NWD1: NACHT and WD repeat domain containing 1. OLFM2: encoding protein Olfactomedin 2 OSCAR: encoding protein Osteoclast-associated
Chromosome_19
Protein-coding gene in the species Homo sapiens
addition, the protein contains a furin-like cysteine-rich region. Furin-like repeat domains have been found in a variety of eukaryotic proteins involved in
R-spondin_3
Mammalian protein found in Homo sapiens
repeat domain. Upon binding cytochrome c and dATP, this protein forms an oligomeric apoptosome. The apoptosome binds and cleaves Procaspase-9 protein
APAF1
Protein-coding gene in the species Homo sapiens
"Core Histones and HIRIP3, a Novel Histone-Binding Protein, Directly Interact with WD Repeat Protein HIRA". Mol. Cell. Biol. 18 (9). UNITED STATES: 5546–56
HIST1H2BK
Protein-coding gene in humans
spliceosome, and contains seven WD repeats, which function in protein-protein interactions. This protein has a sequence similarity to yeast Prp17 protein, which
CDC40
Protein family
SNARE proteins (soluble NSF attachment protein receptors) are a large protein family consisting of at least 24 members in yeasts and more than 60 members
SNARE_protein
Protein family
Drosophila. Each of these genes secretes a protein containing protein-protein interaction regions with leucine-rich repeats and EFGs. Slit2 is mainly expressed
Slit_(protein)
Protein-coding gene in the species Homo sapiens
repeat containing protein 2; also known as Fbxw11 or HOS) is a protein that in humans is encoded by the FBXW11 (F-box and WD repeat domain containing
FBXW11
Protein in animal cells
Dreyfuss G (February 2002). "Gemin5, a novel WD repeat protein component of the SMN complex that binds Sm proteins". The Journal of Biological Chemistry. 277
Survival_of_motor_neuron
Protein-coding gene in the species Homo sapiens
Bittner M, Kolanus W, Schuster A, Holzmann B (October 1998). "The human WD repeat protein WAIT-1 specifically interacts with the cytoplasmic tails of beta7-integrins"
Receptor for activated C kinase 1
Receptor_for_activated_C_kinase_1
Protein-coding gene in the species Homo sapiens
The protein encoded by this gene is a member of the FG repeat containing nucleoporins and is localized to the nuclear pore central plug. This protein associates
Nuclear_pore_glycoprotein_p62
Mammalian protein found in humans
regulatory domain of CBS contains a tandem repeat of two CBS domains of β-α-β-β-α, a secondary structure motif found in other proteins. CBS has a C-terminal
Cystathionine_beta_synthase
Protein-coding gene in the species Homo sapiens
WD repeat-containing protein 37 is a protein that in humans is encoded by the WDR37 gene. This gene encodes a member of the WD repeat protein family.
WDR37
Protein containing at least one F-box domain
(illustrated in the Figure) and WD repeats, which are thought to mediate interactions with SCF substrates. F-box proteins have also been associated with
F-box_protein
Protein-coding gene in the species Homo sapiens
The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different
FBXO9
Protein-coding gene in the species Homo sapiens
enhances the binding of the protein. The name of the domain arises due to the occurrence of leucine as well as, arginine repeats periodically on the α-helix
Myocilin
Protein-coding gene in the species Homo sapiens
WD repeat containing protein 53 (WDR53) is a protein encoded by the WDR53 gene that has been identified in the human genome by the Human Genome Project
WDR53
Mammalian protein found in Homo sapiens
2 different isoforms. CTDP1 has been shown to interact with WD repeat-containing protein 77, GTF2F1 and POLR2A. ENSG00000060069 GRCh38: Ensembl release
CTDP1
Type of genetic component
contain genes for reverse transcriptase, RNA-binding protein, nuclease, and sometimes ribonuclease H domain but they lack the long terminal repeats.
Retrotransposon
Protein family
sequence contains seven WD repeat motifs of about 40 amino acids, each highly conserved and possessing the Trp-Asp dipeptide that gives the repeat its name
G_beta-gamma_complex
Protein-coding gene in the species Homo sapiens
Calothy G, Monneron A (Aug 1996). "A novel calmodulin-binding protein, belonging to the WD-repeat family, is localized in dendrites of a subset of CNS neurons"
STRN
Oxygen-delivering blood cell and the most common type of blood cell
iron-containing biomolecule that can bind oxygen. It is responsible for the red color of the cells and the blood. Each human red blood cell contains approximately
Red_blood_cell
Protein-coding gene in the species Homo sapiens
WD repeat-containing protein 90 is a protein that, in humans, is encoded by the WDR90 gene (16p13.3). This human protein is 1750 amino acids, and has a
WDR90
Protein found in humans
Apolipoprotein B (ApoB) is a protein that in humans is encoded by the APOB gene. Its measurement is commonly used to detect the risk of atherosclerotic
Apolipoprotein_B
Protein-coding gene in the species Homo sapiens
to F-box proteins (proteins containing an F-box motif), such as cyclin F, S-phase kinase-associated protein 2, and other regulatory proteins involved
S-phase kinase-associated protein 1
S-phase_kinase-associated_protein_1
Gene known for its role in breast cancer
modules or as multiple tandem repeats containing two domains. Both of these possibilities can occur in a single protein in a variety of different conformations
BRCA1
Cytoplasmic biomolecular condensates of proteins and RNA occurring in cells under stress
stress granules are biomolecular condensates in the cytosol composed of proteins and RNA that assemble into 0.1–2 μm membraneless organelles when the cell
Stress_granule
Nambudripad R, Smith TF (September 1994). "The ancient regulatory-protein family of WD-repeat proteins". Nature. 371 (6495): 297–300. Bibcode:1994Natur.371..297N
EMC1
Protein-coding gene in the species Homo sapiens
Blanchette-Mackie EJ, Strauss JF (November 2002). "A sperm-associated WD repeat protein orthologous to Chlamydomonas PF20 associates with Spag6, the mammalian
Sperm-associated_antigen_6
Mammalian protein found in Homo sapiens
Bittner M, Kolanus W, Schuster A, Holzmann B (October 1998). "The human WD repeat protein WAIT-1 specifically interacts with the cytoplasmic tails of beta7-integrins"
Integrin_beta_2
Protein-coding gene in the species Homo sapiens
and validated alternative polyadenylation sites. CORO6 protein sequence contains WD-40 repeats. WD40 domain is a structural motif found in Eukaryotes
CORO6
Protein-coding gene in the species Homo sapiens
Bittner M, Kolanus W, Schuster A, Holzmann B (Nov 1998). "The human WD repeat protein WAIT-1 specifically interacts with the cytoplasmic tails of beta7-integrins"
Polycomb_protein_EED
Human gene and protein
"Core histones and HIRIP3, a novel histone-binding protein, directly interact with WD repeat protein HIRA". Mol. Cell. Biol. 18 (9): 5546–56. doi:10.1128/MCB
HIRA
Protein-coding gene in the species Homo sapiens
find in repeat studies. Members of the SLITRK family, such as SLITRK1, are integral membrane proteins with 2 N-terminal leucine-rich repeat (LRR) domains
SLITRK1
Protein-coding gene in the species Homo sapiens
M, Dreyfuss G (2002). "Gemin5, a novel WD repeat protein component of the SMN complex that binds Sm proteins". J. Biol. Chem. 277 (7): 5631–6. doi:10
Gem-associated_protein_4
Protein-coding gene in the species Homo sapiens
Dreyfuss G (February 2002). "Gemin5, a novel WD repeat protein component of the SMN complex that binds Sm proteins". The Journal of Biological Chemistry. 277
DDX20
Molecule that carries genetic information
cells, telomeres are usually lengths of single-stranded DNA containing several thousand repeats of a simple TTAGGG sequence. These guanine-rich sequences
DNA
Cytosolic multiprotein complex that mediates the activation of Caspase 1
oligomerization domain and leucine-rich repeat-containing receptors), AIM2 (absent in melanoma 2), IFI16 (IFN-inducible protein 16), and pyrin. Through their caspase
Inflammasome
Protein-coding gene in the species Homo sapiens
Jeon AH, Hwang SG, Chun JS, Lee CW (September 2004). "WD repeat-containing mitotic checkpoint proteins act as transcriptional repressors during interphase"
BUB3
Protein family
PMID 16258276. Cerna D, Wilson DK (2005). "The structure of Sif2p, a WD repeat protein functioning in the SET3 corepressor complex". J Mol Biol. 351 (4):
LisH_domain
Protein-coding gene in humans
DNA excision repair protein ERCC-8 is a protein that in humans is encoded by the ERCC8 gene. This gene encodes a WD repeat protein, which interacts with
ERCC8
Sequence in a genome
Geng Y, Zheng R, Chakraborty A, Freeman B, et al. (October 2010). "A WD-repeat protein stabilizes ORC binding to chromatin". Molecular Cell. 40 (1): 99–111
Origin_of_replication
Protein-coding gene in the species Homo sapiens
re-form (Figure 2). The WRAP53β protein is highly evolutionary conserved, with homologs (confined to its WD40 repeats) in vertebrates, invertebrates,
WRAP53
Protein-coding gene in the species Homo sapiens
Dreyfuss G (Feb 2002). "Gemin5, a novel WD repeat protein component of the SMN complex that binds Sm proteins". The Journal of Biological Chemistry. 277
Small nuclear ribonucleoprotein D1
Small_nuclear_ribonucleoprotein_D1
Medical condition
Sensorineural Deafness CAused by a Deletion Involving OA1 and a Novel Gene Containing WD-40 Repeats". The American Journal of Human Genetics. 64 (6): 1604–1616. doi:10
Ocular albinism late onset sensorineural deafness
Ocular_albinism_late_onset_sensorineural_deafness
Protein found in humans
sites, can be divided into 30 short consensus repeats (SCRs) (also known as complement control protein repeats (CCPs) or sushi domains), each having 60 to
Complement_receptor_1
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