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VINTAFOLIDE

  • Vintafolide

    • Chemical compound

    Vintafolide is an investigational targeted cancer therapeutic currently under development by Endocyte and Merck & Co. It is a small molecule drug conjugate

    Vintafolide

    Vintafolide

    Vintafolide

  • Technetium (99mTc) etarfolatide

    • Chemical compound

    together with the corresponding small molecule drug conjugate (SMDC) vintafolide in a Phase 3 study in platinum-resistant ovarian cancer and in a Phase

    Technetium (99mTc) etarfolatide

    Technetium (99mTc) etarfolatide

    Technetium_(99mTc)_etarfolatide

  • Endocyte

    • American pharmaceutical company

    polycystic kidney disease/ADPKDor PKD). Endocyte’s lead drug candidate is vintafolide, an investigational targeted cancer therapeutic in late-stage development

    Endocyte

    Endocyte

  • Ovarian cancer

    • Cancer originating in or on the ovary

    exacerbate bowel disease, leading to fistulae or bowel perforation. Vintafolide, which consists of an antifolate conjugated with vinblastine, is also

    Ovarian cancer

    Ovarian cancer

    Ovarian_cancer

  • Small molecule drug conjugate

    • and generate SMDCs for different diseases. The most advanced SMDC is vintafolide, a derivative of the anti-mitotic chemotherapy drug vinblastine which

    Small molecule drug conjugate

    Small_molecule_drug_conjugate

  • Targeted therapy

    • Type of therapy

    chronic lymphocytic leukemia, and Waldenström's macroglobulinemia. Vintafolide is a small molecule drug conjugate consisting of a small molecule targeting

    Targeted therapy

    Targeted therapy

    Targeted_therapy

  • ATC code L01

    • Pharmaceutical drug classification

    Vincristine L01CA03 Vindesine L01CA04 Vinorelbine L01CA05 Vinflunine L01CA06 Vintafolide L01CB01 Etoposide L01CB02 Teniposide L01CC01 Demecolcine L01CD01 Paclitaxel

    ATC code L01

    ATC_code_L01

  • List of compounds with carbon numbers 50+

    • 124853-83-4 C86H97Cl3N10O26 oritavancin 171099-57-3 C86H109N21O26S2 vintafolide 742092-03-1 C86H128O2 menaquinone-15 106347-61-9 C86H144O40 crocosmioside

    List of compounds with carbon numbers 50+

    List_of_compounds_with_carbon_numbers_50+

  • Purdue Research Park

    • Research park network in Indiana, United States

    AgroSciences Endocyte Endocyte, a pharmaceutical company, is developing EC145 (Vintafolide), a candidate drug for use in chemotherapy-resistant patients with non-small-cell

    Purdue Research Park

    Purdue_Research_Park

  • Folate targeting

    • conjugates have entered clinical trials for the treatment of cancer: Vintafolide (EC145) represents a novel water-soluble FA conjugate of the powerful

    Folate targeting

    Folate_targeting

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