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Area of tissue in the eye
The trabecular meshwork is an area of tissue in the eye located around the base of the cornea, near the ciliary body, and is responsible for draining
Trabecular_meshwork
Tissue element that supports or anchors a framework of parts within a body or organ
corpus spongiosum) or providing a cell filter (as in the trabecular meshwork of the eye). Trabecular bone, also called cancellous bone, is porous bone composed
Trabecula
Group of eye diseases related to poor retinal and nerve perfusion
provides nutrients. The aqueous humor normally drains through the trabecular meshwork. In open-angle glaucoma, the drainage is impeded, causing the build
Glaucoma
Eye muscle which is used for focussing
which insert into the trabecular meshwork in the anterior chamber of the eye, cause an increase and decrease in the meshwork pore size, respectively
Ciliary_muscle
Topics referred to by the same term
Meshwork may refer to: Mesh work Mesh networking Trabecular meshwork, an area of tissue in the eye Meshwork (album), 1995 album by German band X Marks
Meshwork
Protein-coding gene in the species Homo sapiens
Myocilin, trabecular meshwork inducible glucocorticoid response (TIGR), also known as MYOC, is a protein which in humans is encoded by the MYOC gene.
Myocilin
Lymphatic-like vessel in the eye
nearest to the aqueous humor, it is covered and held open by the trabecular meshwork. This creates outflow resistance against the aqueous humor. While
Schlemm's_canal
Fluid in the anterior segment of the eye
and glucose) for the avascular ocular tissues; posterior cornea, trabecular meshwork, lens, and anterior vitreous. May serve to transport ascorbate in
Aqueous_humour
Surgical removal of trabecular tissue in the eye
glaucoma to relieve intraocular pressure by removing part of the eye's trabecular meshwork and adjacent structures. It is the most common glaucoma surgery performed
Trabeculectomy
Measure of bone texture
number of trabeculae, increased inter-trabecular distance, and a loss connectivity of the trabecular meshwork. Moreover, reduction of cortical bone thickness
Trabecular_bone_score
Space in the eye
inflammatory signs in the anterior chamber. In glaucoma, blockage of the trabecular meshwork prevents the normal outflow of aqueous humour, resulting in increased
Anterior_chamber_of_eyeball
Medical condition
less pliable degenerated red blood cells (ghost cells) block the trabecular meshwork and increase the pressure inside eyes. The ghost cells develop within
Ghost_cell_glaucoma
Type of eye surgery
Trabeculectomy is a guarded filtering procedure that removes part of the trabecular meshwork. Full thickness procedures include sclerectomy, posterior lip sclerectomy
Glaucoma_surgery
Medication used to treat glaucoma and dry mouth
activating cholinergic receptors of the muscarinic type which cause the trabecular meshwork to open and the aqueous humor to drain from the eye. Pilocarpine
Pilocarpine
Medical condition
ocular and extraocular, such as in the anterior chamber structures, trabecular meshwork, central disc, zonular fibres, anterior hyaloid membrane, pupillary
Pseudoexfoliation_syndrome
Surgical instrument for glaucoma surgery
surgical management of adult, juvenile, and infantile glaucoma. The trabecular meshwork is a major site of resistance to aqueous humor outflow. As angle
Trabectome
Cranial nerve connecting the eye to the brain
pressure that damages the optic nerve as it exits the eyeball. The trabecular meshwork assists the drainage of aqueous humor fluid. The presence of excess
Optic_nerve
Colored part of an eye
in front of the root of the iris is the region referred to as the trabecular meshwork, through which the aqueous humour constantly drains out of the eye
Iris_(anatomy)
Annular structure composed of collagen in the human eye
lens) of the ciliary muscle, and is attached posteriorly to the trabecular meshwork. Open-angle glaucoma (OAG) and closed-angle glaucoma (CAG) may be
Scleral_spur
Part of eye
of the eye located between the cornea and iris which contains the trabecular meshwork. The size of this angle is an important determinant of the rate aqueous
Anterior_chamber_angle
via an internal approach through the trabecular meshwork into Schlemm's Canal, bypassing the trabecular meshwork and facilitating flow of aqueous from
Minimally invasive glaucoma surgery
Minimally_invasive_glaucoma_surgery
Dark coloration of the eye
structures. Overproduction of pigment by these cells can block the trabecular meshwork through which fluid drains from the eye. The increased fluid in the
Ocular_melanosis
Eye structure
eye Fibrous tunic (outer) Sclera Episcleral layer Schlemm's canal Trabecular meshwork Cornea Limbus layers Epithelium Bowman's Stroma Dua's layer Descemet's
Lens_(vertebrate_anatomy)
Part of the eye's ciliary body
eye Fibrous tunic (outer) Sclera Episcleral layer Schlemm's canal Trabecular meshwork Cornea Limbus layers Epithelium Bowman's Stroma Dua's layer Descemet's
Pars_plana
Part of the nervous system
eye Fibrous tunic (outer) Sclera Episcleral layer Schlemm's canal Trabecular meshwork Cornea Limbus layers Epithelium Bowman's Stroma Dua's layer Descemet's
Sensory_nervous_system
Removal of opacified lens from the eye
angle between the iris and cornea, blocking drainage through the trabecular meshwork and causing an increase in intraocular pressure. Mechanical pupillary
Cataract_surgery
Laser treatment for open angle glaucoma or ocular hypertension
Specifically, an argon laser is used to improve drainage through the eye's trabecular meshwork, from which the aqueous humour drains. This helps reduce intraocular
Trabeculoplasty
Body position lying flat on the back with the feet slightly above the head
visualise the inferior trabecular meshwork. Some joysticking of the globe may be required with an appropriate goniolens to bring the meshwork into view.[citation
Trendelenburg_position
Protein-coding gene in the species Homo sapiens
BMP5 is inhibited by chordin and noggin. It is expressed in the trabecular meshwork and optic nerve head and may have a role in the development and normal
Bone_morphogenetic_protein_5
Medical condition
where surgeons cut into the eye's drainage angle to access the trabecular meshwork, using a gonioscope for visibility. If the drainage angle isn't clearly
Primary_congenital_glaucoma
List of Surgical Removals
the tonsils. Trabeculectomy is the removal of part of the eye's trabecular meshwork as a treatment for glaucoma. Tumorectomy is the surgical removal
List_of_-ectomies
Eye condition
nitrate or non-nitrate vasodilators induces relaxation of the bovine trabecular meshwork and ciliary muscle". Since spasm of accommodation is a result of
Spasm_of_accommodation
Sensory organ of vision
flow; 6. Pupil, 7. Corneosclera or Fibrous tunic with 8. Cornea, 9. Trabecular meshwork and Schlemm's canal. 10. Corneal limbus and 11. Sclera; 12. Conjunctiva
Human_eye
Fluid pressure inside the eye
drainage of aqueous humour by the ciliary body and its drainage via the trabecular meshwork and uveoscleral outflow. The reason for this is that the vitreous
Intraocular_pressure
Genetic condition involving hearing loss and depigmentation
tissue of the eye, such as the stroma of the iris and cornea and the trabecular meshwork, and melanocytes, including those in the stroma of the iris that
Waardenburg_syndrome
Viscoelatic materials used in ophthalmic surgery to maintain eye shape
of the large molecules of the OVD causing reduced outflow in the trabecular meshwork. Various drugs have been used to limit pressure spikes, and while
Ophthalmic viscosurgical device
Ophthalmic_viscosurgical_device
Contraction of ciliary muscle
can cause pseudomyopia. Cyclospasm may also exert tensions on the trabecular meshwork, opening the pores and facilitating outflow of the aqueous humour
Cyclospasm
Accumulation of pigment cells within the eye's internal fluid
in the anterior chamber in such a way that they begin to clog the trabecular meshwork (the major site of aqueous humour drainage), which can in turn prevent
Pigment_dispersion_syndrome
Protein-coding gene in the species Homo sapiens
to toxic substance visual perception blood vessel morphogenesis trabecular meshwork development negative regulation of NF-kappaB transcription factor
CYP1B1
Drug used in narrow angle glaucoma
muscarinic receptors in the eye, which constricts the pupil and opens the trabecular meshwork to facilitate aqueous humor outflow. It was used as a topical drop
Aceclidine
Minimally invasive glaucoma surgery
laser trabeculostomy (ELT) is a procedure to create holes in the trabecular meshwork to reduce intraocular pressure. It uses a XeCl 308 nm excimer laser
Excimer_laser_trabeculostomy
Front third of the eye
Aqueous humour flow; 6. Pupil, 7. Corneosclera with 8. Cornea, 9. Trabecular meshwork and Schlemm's canal. 10. Corneal limbus and 11. Sclera; 12. Conjunctiva
Anterior_segment_of_eyeball
Line of the cornea of the eye
Gonioscopy of the anterior chamber angle. Labeled structures: 1. Schwalbe's line, 2. Trabecular meshwork (TM), 3. Scleral spur, 4. Ciliary body, 5. Iris
Schwalbe's_line
Organ of the lymphatic system
i.e., a meshwork or fibers called reticulum with white blood cells enmeshed in it. The regions where there are few cells within the meshwork are known
Lymph_node
Glaucoma caused by uveitis or its treatments
peripheral anterior synechiae (PAS), or adhesions between the iris and trabecular meshwork, the tissue responsible for draining aqueous humour from the eye
Uveitic_glaucoma
Drug class
changes in extracellular matrix and to widening of spaces within the trabecular meshwork. This work led to the development of prodrugs of PGF2α, including
Prostaglandin_analogue
Medical condition
eventually goes out of the eye through the connective tissue called trabecular meshwork. In healthy eyes, the drainage and the secretion of aqueous humor
Tunnel_vision
Chemical compound
ongoing. As of 2019 it was thought that bimatoprost worked via the trabecular meshwork and uveoscleral pathways. Bimatoprost is well absorbed through the
Bimatoprost
Where rod and cone of the eye terminate
eye Fibrous tunic (outer) Sclera Episcleral layer Schlemm's canal Trabecular meshwork Cornea Limbus layers Epithelium Bowman's Stroma Dua's layer Descemet's
Ora_serrata
Type of substances designed to affect the nervous system
in outflow of aqueous humor by widening Schlemm's canal and the trabecular meshwork, lowering the intraocular pressure of patients with glaucoma. The
Autonomic_drug
Fourth layer of cornea( first being the outermost and sixth being the innermost)
eye Fibrous tunic (outer) Sclera Episcleral layer Schlemm's canal Trabecular meshwork Cornea Limbus layers Epithelium Bowman's Stroma Dua's layer Descemet's
Dua's_layer
Chemical compound
uveoscleral outflow while the nitrous oxide increases outflow via the trabecular meshwork. The most common side effects include conjunctival (eye) redness
Latanoprostene_bunod
Disorder of the human eye
of a mature cataract. The leaked lens material may obstruct the trabecular meshwork leading to decreased aqueous humor outflow and increased intraocular
Lens_induced_glaucomas
Chemical compound
of drainage tissues and decreased outflow resistance in e.g. the trabecular meshwork. Latrunculin B causes marked and dose-dependent reductions in pollen
Latrunculin
Chemical compound
aqueous humor production or inadequate drainage of the humor via the trabecular meshwork. Inhibition of carbonic anhydrase in the ciliary processes of the
Brinzolamide
Eye disorder
vitreous flow resulting from inflammation in the structures of the trabecular meshwork, and the sedimentation of inflamed cells. Specifically for viral
Secondary_glaucoma
Region of the eyeball between the iris and lens
in anterior bowing of the peripheral iris and obstruction of the trabecular meshwork. This may result in an acute attack of angle closure glaucoma. Surgical
Posterior_chamber_of_eyeball
Measurement of the angle between an eye's iris and cornea
chamber. A wide angle allows sufficient drainage of humour through the trabecular meshwork (unless obstructed), whereas a narrow angle may impede the drainage
Gonioscopy
Medical condition
Schwalbe's line, which can be thin or thick and extend over the trabecular meshwork, obscuring the scleral spur and even pulling the iris and producing
Axenfeld–Rieger_syndrome
Protein-coding gene in the species Homo sapiens
transcription by RNA polymerase II transcription, DNA-templated trabecular meshwork development camera-type eye development regulation of transcription
FOXE3
Protein and coding gene in humans
"The identification of myocilin-associated proteins in the human trabecular meshwork". Exp. Eye Res. 82 (6): 1046–52. doi:10.1016/j.exer.2005.09.016.
CKM_(gene)
Topics referred to by the same term
TIGR plant transcript assembly database TIGR plant repeat database Trabecular meshwork inducible glucocorticoid response (TIGR) or MYOC, a human gene Tandem
Tigr
Protein-coding gene in the species Homo sapiens
(Jul 1999). "Multiple cyclic nucleotide phosphodiesterases in human trabecular meshwork cells" (PDF). Investigative Ophthalmology & Visual Science. 40 (8):
PDE4A
Medical condition
abnormal cells retain their ability to divide and extend onto the trabecular meshwork to cause glaucoma in up to 40% of cases. Corneal dystrophy Albrecht
Posterior polymorphous corneal dystrophy
Posterior_polymorphous_corneal_dystrophy
Protein found in humans
Schneemann A (2003). "Optineurin gene expression level in human trabecular meshwork does not change in response to pressure elevation". Ophthalmic Research
Optineurin
Medical condition
Davidorf suggested that the elevated IOP may be due to obstruction of trabecular meshwork by pigmented cells representing photoreceptor outer segments from
Schwartz–Matsuo_syndrome
Italian medical researcher
significantly higher levels of 8-hydroxy-2′-deoxyguanosine (8-OH-dG) in the trabecular meshwork of eyes of glaucoma patients. In similar research, he examined the
Alberto_Izzotti
Medical condition
enters the eye through the ciliary body and exits the eye through the trabecular meshwork. Whether macular surgery or vitrectomy contributes to an increased
Ocular_hypertension
parenteral nutrition – TP-38 immunotoxin – tPA – TPA – Trabecular cancer – Trabecular meshwork – Transabdominal ultrasound – Transcutaneous electric nerve
Index_of_oncology_articles
Form of minimally invasive surgery used in ophthalmology
first successful use of photodisruption was in 1972, on a case of trabecular meshwork. Photodisruption came to wide use in the early 1980s for the treatment
Photodisruption
Chemical compound
affects intraocular pressure, or IOP, "by directly acting on the trabecular meshwork, thereby increasing conventional outflow through the Schlemm’s canal
Ripasudil
Combination drug
pressure in the eye by increased draining of aqueous humor via the trabecular meshwork. Timolol is a nonselective beta blocker, which lowers eye pressure
Bimatoprost/timolol
Chemical compound
kinase. This appears to increase outflow of aqueous humor through the trabecular meshwork, and also to reduce pressure in the veins of the episcleral layer
Netarsudil
Protein-coding gene in the species Homo sapiens
"Mitochondrial defects and dysfunction in calcium regulation in glaucomatous trabecular meshwork cells". Investigative Ophthalmology & Visual Science. 49 (11): 4912–22
PPIF
Protein highly abundant in the cochlea and vestibule of the inner ear
have been reported in this gene. Cochlin has been identified in the trabecular meshwork (TM) of glaucoma patients, but not in healthy controls. The TM is
Cochlin
Type of eye surgery procedure
eye's intraocular pressure (IOP). The device works by bypassing the trabecular meshwork and redirecting the outflow of aqueous humour through a small tube
Glaucoma_valve
Protein-coding gene in the species Homo sapiens
that the stimulation of FP receptors located on Ciliary muscle and trabecular meshwork cells of the eye widens the drainage channels (termed the uveoscleral
Prostaglandin_F_receptor
Protein-coding gene in the species Homo sapiens
Raymond V, et al. (2003). "Gene expression profile of the human trabecular meshwork: NEIBank sequence tag analysis". Invest. Ophthalmol. Vis. Sci. 44
BRD7
Technique of surgical cataract extraction
OVDs can cause raised intraocular pressure (IOP) by blocking the trabecular meshwork until they dissipate. IOP spikes can cause damage to the optic nerve
Manual small incision cataract surgery
Manual_small_incision_cataract_surgery
Gene of the species Homo sapiens
"The identification of myocilin-associated proteins in the human trabecular meshwork". Exp. Eye Res. 82 (6): 1046–52. doi:10.1016/j.exer.2005.09.016.
CAP1
Protein-coding gene in the species Homo sapiens
Lam DS, Pang CP (May 2008). "Gene expression profiles of human trabecular meshwork cells induced by triamcinolone and dexamethasone". Investigative
SOX30
Medical condition
proliferates onto the iris forming a membrane that then obstructs the trabecular meshwork, leading to iris distortion. Nodule formation can also occur when
Iridocorneal endothelial syndrome
Iridocorneal_endothelial_syndrome
Protein-coding gene in the species Homo sapiens
(1999). "Multiple cyclic nucleotide phosphodiesterases in human trabecular meshwork cells". Invest. Ophthalmol. Vis. Sci. 40 (8): 1745–52. PMID 10393044
PDE7A
American-Hungarian physicist
micron-resolution OCT imaging, it is possible to precisely identify the trabecular meshwork and create precise drainage pathways that connect the anterior chamber
Tibor_Juhasz
Protein-coding gene in the species Homo sapiens
S, Malyukova I (Jun 2003). "Gene expression profile of the human trabecular meshwork: NEIBank sequence tag analysis". Investigative Ophthalmology & Visual
RERE
Protein-coding gene in the species Homo sapiens
"The identification of myocilin-associated proteins in the human trabecular meshwork". Exp. Eye Res. 82 (6): 1046–52. doi:10.1016/j.exer.2005.09.016.
Far upstream element–binding protein 1
Far_upstream_element–binding_protein_1
Protein-coding gene in the species Homo sapiens
Raymond V, et al. (2003). "Gene expression profile of the human trabecular meshwork: NEIBank sequence tag analysis". Invest. Ophthalmol. Vis. Sci. 44
Olfactomedin_2
Protein-coding gene in the species Homo sapiens
Raymond V; et al. (2003). "Gene expression profile of the human trabecular meshwork: NEIBank sequence tag analysis". Invest. Ophthalmol. Vis. Sci. 44
ZNF33A
American ophthalmologist
(1960-10-01). "The Limbal Area*: With Particular Reference to the Trabecular Meshwork in Health and Disease the XIV Francis I. Proctor Lecture". American
Georgiana_Dvorak-Theobald
cerebellum tooth torcular herophili torso torticollis torus trabecula trabecular meshwork trachea tract of Lissauer tractus solitarius tragus transverse cervical
Index_of_anatomy_articles
Protein-coding gene in the species Homo sapiens
Malyukova I (June 2003). "Gene expression profile of the human trabecular meshwork: NEIBank sequence tag analysis". Investigative Ophthalmology & Visual
ALDH7A1
MeSH A09.371.060.217.659 – limbus corneae MeSH A09.371.060.932 – trabecular meshwork MeSH A09.371.337.338 – eyelashes MeSH A09.371.337.614 – meibomian
List_of_MeSH_codes_(A09)
Protein-coding gene in the species Homo sapiens
Raymond V, et al. (2003). "Gene expression profile of the human trabecular meshwork: NEIBank sequence tag analysis". Invest. Ophthalmol. Vis. Sci. 44
LRP10
Protein-coding gene in the species Homo sapiens
"The identification of myocilin-associated proteins in the human trabecular meshwork". Experimental Eye Research. 82 (6): 1046–1052. doi:10.1016/j.exer
Olfactomedin-like_3
Protein-coding gene in the species Homo sapiens
localize to distinct foci in the nucleoplasm, to the nuclear rim, and to meshwork-like structures throughout the cytoplasm. This gene is thought to be involved
RAE1
Protein-coding gene in the species Homo sapiens
Raymond V, et al. (2003). "Gene expression profile of the human trabecular meshwork: NEIBank sequence tag analysis". Invest. Ophthalmol. Vis. Sci. 44
RRAGB
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