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Chemical compound
Thienamycin (also known as thienpenem) is one of the most potent naturally produced antibiotics known thus far, discovered in Streptomyces cattleya in
Thienamycin
Carbapenem antibiotic
stable version of the natural product thienamycin, which is produced by the bacterium Streptomyces cattleya. Thienamycin has antibacterial activity, but is
Imipenem
Ertapenem Faropenem Imipenem Meropenem Panipenem Razupenem Tebipenem pivoxil Thienamycin Aztreonam Tigemonam Nocardicin A Tabtoxinine β-lactam (does not inhibit
List_of_β-lactam_antibiotics
Class of highly effective antibiotic agents
antibiotics were originally developed at Merck & Co. from the carbapenem thienamycin, a naturally derived product of Streptomyces cattleya. Concern has arisen
Carbapenem
Species of bacterium
is a Gram-positive bacterium which makes cephamycin, penicillin and thienamycin. The bacterium expresses a fluorinase enzyme, and the organism has been
Streptomyces_cattleya
English chemist and science writer
chemistry he had developed, included the synthesis of the natural products thienamycin, nonactin, and sparteine. Fleming, Ian; Woodward, R. B. (1973). "A synthesis
Ian_Fleming_(chemist)
Chemical compound
(1986). "Biosynthesis of fluorothreonine and fluoroacetic acid by the thienamycin producer, Streptomyces cattleya". The Journal of Antibiotics. 39 (2):
4-Fluoro-L-threonine
Microbe with cell wall mostly removed
spheroplasts. This screen enabled the discovery of fosfomycin, cephamycin C, thienamycin and several carbapenems. Specially prepared giant spheroplasts of Gram-negative
Spheroplast
Kropp H, Sundelof JG, Hajdu R, Kahan FM (July 1982). "Metabolism of thienamycin and related carbapenem antibiotics by the renal dipeptidase, dehydropeptidase"
Membrane_dipeptidase
MeSH D02.065.589.099.124 – carbapenems MeSH D02.065.589.099.124.300 – thienamycins MeSH D02.065.589.099.124.300.500 – imipenem MeSH D02.065.589.099.249
List_of_MeSH_codes_(D02)
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